CN104187012A - Preprocessing wall-breaking method for Chinese herbal medicines for feeding - Google Patents
Preprocessing wall-breaking method for Chinese herbal medicines for feeding Download PDFInfo
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- CN104187012A CN104187012A CN201410271863.2A CN201410271863A CN104187012A CN 104187012 A CN104187012 A CN 104187012A CN 201410271863 A CN201410271863 A CN 201410271863A CN 104187012 A CN104187012 A CN 104187012A
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Abstract
A preprocessing wall-breaking method for Chinese herbal medicines for feeding comprises the following steps: (1) crushing Chinese herbal medicines and sieving by a 40-60 mesh sieve, so as to obtain a Chinese herbal medicine powder; (2) spreading water into the sieved Chinese herbal medicine powder with stirring, so as to enable the water content to be 85-90% and guarantee water to be uniformly dispersed in the Chinese herbal medicine powder, putting the Chinese herbal medicine powder subjected to water spreading into a sealed jar, and controlling the volume of the naturally piled powder to be 50-60% of the volume of the sealed jar; (3) sealing the sealed jar, vacuumizing the jar and keeping for 15-20 min, then filling the jar with nitrogen for pressurizing and keeping for 15-20 min, and repeating for 3-4 times; and (4) drying at a low temperature to have the water content of 60-70%, and adding cellulase for enzymatic hydrolysis for 6-8 h. The method is simple and practicable, is easy to operate, does not need expensive equipment and raw materials, is low in cost and excellent in wall breaking effect, and is applicable to large-scale industrialized production.
Description
Technical field
The present invention relates to fowl poultry field of Chinese herbal medicine technology, especially relate to a kind of preprocess method of fowl poultry Chinese herbal medicine.
Background technology
Chinese herbal medicine is the general name of Chinese medicine and herbal medicine.Chinese medicine refers under traditional Chinese veterinary medicine theoretical direction, be applied to the natural drug of clinical prevention disease, and herbal medicine refers to the plant-based medicine of the disease preventing and treating that animal doctor among the people continues to use or region spreads.Chinese herbal feed additive refers to that the traditional theory of relation between the property of medicine (flat, cold, cool, warm, heat), flavour of a drug (pungent, sour, bitter, sweet, one-tenth) and the thing taking natural Chinese medicinal herb is basis, taking modern animal nutrition and thremmatology theory as guidance, and actual in conjunction with producing, single or compound Chinese herb feed additive or the mixed feeding agent of developing.Its function is to prevent and cure diseases, promotes certain physiological action of animal or improves organismic internal environment, thereby the production performance of raising animal is that the producer creates more economic benefits.
There is certain difference with the application of mankind's Chinese herbal medicine in the application of feed Chinese herbal medicine, in the time that the mankind apply Chinese herbal medicine, can not be with the application of full medicine, and use after can only adopting certain brewing method effective component extracting, but this method can increase cost while being applied in feed greatly.According to the feature of feed, in animal and fowl fodder, can add the full medicine of Chinese herbal medicine, can reduce like this processing cost, but we know, Chinese herbal medicine is as herbaceous plant, its root, stem and leaf all contains a large amount of cell membranes, and the main component of cell membrane is cellulosic and pectic substance, and these compositions not only can strengthen pulverizing difficulty, cause the increase of processing cost, also can limit smashing fineness, cause the low of animal absorptivity, so just can only be by increasing consumption with the lower absorptivity of balance.
When these problems make Chinese herbal medicine as feed addictive, dosage is often bigger than normal, generally all 1 ~ 2%, if the consumption of pine needle meal is up to 5%, has not only increased product cost, wastes medicine, and affects palatability and the nutrition-allocated proportion of feed.Solution is except seeking little, the effective Chinese herbal medicine of consumption as feed addictive, mainly should the cell membrane of Chinese herbal medicine abolish aspect seeking breakthrough.
Cell membrane for Chinese herbal medicine is abolished technology, has at present comminution by gas stream, enzymatic isolation method etc.Wherein comminution by gas stream has good shell-broken effect to duricrust Chinese herbal medicine, but need to use large-scale airflow machine, expensive, make the Chinese herbal medicine after broken wall also very expensive, be difficult at feed with promoting the use of in medicine, although and enzymatic isolation method cost is low, enzyme be difficult to effectively the to degrade cell membrane of Chinese herbal medicine, enzymolysis efficiency is low, makes pretreated Chinese herbal medicine still have the difficult problem absorbing.
Summary of the invention
The problems referred to above that exist for prior art, the applicant provides a kind of feeding Chinese herbal medicine pretreatment wall-breaking method.This method is simple and practical, and easily operation, does not need expensive equipment and raw material, and with low cost, shell-broken effect excellence, is applicable to large-scale industrial production.
Technical scheme of the present invention is as follows:
A kind of feeding Chinese herbal medicine pretreatment wall-breaking method, comprises the steps:
(1) Chinese herbal medicine powder was broken to 40 ~ 60 mesh sieves, obtained herbal powder;
(2) in the herbal powder after sieving, sprinkle water while stirring, making its water content is 85 ~ 90%, and moisture is uniformly dispersed in herbal powder; Herbal powder after watering is put into hermetically sealed can, and the volume of described powder natural packing accounts for 50 ~ 60% of hermetically sealed can volume;
(3) hermetically sealed can is sealed, vacuumize wherein, vacuum is-0.5Mpa ~-1.2Mpa to keep 15 ~ 20 minutes; Then be filled with wherein nitrogen pressurization, pressure is 0.5Mpa ~ 1.2Mpa, keeps 15 ~ 20 minutes; 3 ~ 4 times so repeatedly;
(4) herbal powder low temperature drying step (4) being obtained, to water content 60 ~ 70%, adds cellulase to carry out enzymolysis, 6 ~ 8 hours time.
When step (3) vacuumizes and pressurizes, to hermetically sealed can heating, temperature is 25 ~ 40 DEG C.Temperature to hermetically sealed can heating is higher, and the pressure vacuumizing is higher, and the pressure of pressurization is lower, and the retention time is shorter.
Described in step (4), the mass ratio of cellulase and herbal powder is 0.6 ~ 0.8g:50g.The enzyme work of cellulase described in step (4) is 13000 ~ 40000 u/g.Described in step (4), the temperature of low temperature drying is 40 ~ 60 DEG C.
Wherein 40 object powder particle sizes are 420 microns, and 60 object powder particle sizes are 250 microns.
The technique effect that the present invention is useful is:
Method provided by the present invention is without expensive device, only need a Roughpulverizer, a pressure-resistant seal tank that can vacuumize to produce, in processing procedure except cellulase, do not need other chemical reagent and biological raw material, the cost of whole preprocessing process is very low, even medium-sized and small enterprises also can be easy to use.
The destroyed sporoderm-broken rate of cell membrane of the Chinese herbal medicine that this method processing obtains passes through determination of cell count at 85 ~ 97%(), if while needing service efficiency higher, only need to do vacuumize several times and pressurize more, or the temperature that vacuumizes and pressurize raises, or extend the time that vacuumizes and pressurize, or prolongation enzymolysis time, can bring up to sporoderm-broken rate more than 97%, be very easy to regulate.
This can add according to the addition on tcm theory Chinese herbal medicine after treatment, without ensureing drug effect by strengthening addition, not only save Chinese herbal medicine resource, and enter refuse in fowl carcass still less, metabolism, the toxin expelling burden of fowl poultry are alleviated, reduce toxin deposition, reduced to a certain extent side effects of pharmaceutical drugs.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is specifically described.
Embodiment 1
This feeding cordate houttuynia pretreatment wall-breaking method comprises the steps:
(1) herba houttuyniae powder was broken to 40 mesh sieves, obtained Heartleaf Houttuynia Herb;
(2) in the Heartleaf Houttuynia Herb after sieving, sprinkle water while stirring, making its water content is 90%, and moisture is uniformly dispersed in Heartleaf Houttuynia Herb; Heartleaf Houttuynia Herb after watering is put into hermetically sealed can, and the volume of powder natural packing accounts for 60% of hermetically sealed can volume;
(3) hermetically sealed can is sealed, vacuumize wherein, vacuum is-1.2Mpa to keep 15 minutes; Then be filled with wherein nitrogen pressurization, pressure is 1.2Mpa, keeps 15 minutes; 4 times so repeatedly; When vacuumizing and pressurizeing, to hermetically sealed can heating, temperature is 25 DEG C;
(4) Heartleaf Houttuynia Herb step (4) being obtained to water content 70%, adds cellulase to carry out enzymolysis at 40 DEG C of low temperature dryings, and 8 hours time, the mass ratio of its cellulase and Heartleaf Houttuynia Herb is 0.8g:50g, and the enzyme work of cellulase is 13000 u/g.
Adopt cell counting, choose Chinese herbal medicine and the complete Chinese herbal medicine of pretreatment broken wall of the unprocessed mistake of equal in quality, be configured to respectively the suspension that concentration is identical, the identical volume of respectively asking for, be placed on slide, counting under the microscope, has the cell quantity of cell membrane in the Chinese herbal medicine of (having the cell quantity in the Chinese herbal medicine after the cell quantity-pretreatment of cell membrane with cell membrane in the Chinese herbal medicine of unprocessed mistake)/unprocessed mistake, obtain sporoderm-broken rate.
The sporoderm-broken rate that embodiment 1 processes gained cordate houttuynia is 85%.
Embodiment 2
This feeding cortex albiziae pretreatment wall-breaking method comprises the steps:
(1) cortex albiziae was crushed to 60 mesh sieves, obtained Silktree Albizia Bark;
(2) in the Silktree Albizia Bark after sieving, sprinkle water while stirring, making its water content is 85%, and moisture is uniformly dispersed in Silktree Albizia Bark; Silktree Albizia Bark after watering is put into hermetically sealed can, and the volume of powder natural packing accounts for 50% of hermetically sealed can volume;
(3) hermetically sealed can is sealed, vacuumize wherein, vacuum is-0.5Mpa to keep 20 minutes; Then be filled with wherein nitrogen pressurization, pressure is 0.5MpaMpa, keeps 20 minutes; 3 times so repeatedly; When vacuumizing and pressurizeing, to hermetically sealed can heating, temperature is 30 DEG C;
(4) Silktree Albizia Bark step (4) being obtained to water content 60%, adds cellulase to carry out enzymolysis at 50 DEG C of low temperature dryings, and 7 hours time, the mass ratio of its cellulase and Silktree Albizia Bark is 0.6g:50g, and the enzyme work of cellulase is 40000 u/g.
The sporoderm-broken rate that embodiment 12 processes gained cortex albiziae is 92%.
Embodiment 3
This feeding Radix Glycyrrhizae pretreatment wall-breaking method comprises the steps:
(1) licorice powder was broken to 40 mesh sieves, obtained Radix Glycyrrhizae powder;
(2) in the Radix Glycyrrhizae powder after sieving, sprinkle water while stirring, making its water content is 90%, and moisture is uniformly dispersed in Radix Glycyrrhizae powder; Radix Glycyrrhizae powder after watering is put into hermetically sealed can, and the volume of powder natural packing accounts for 60% of hermetically sealed can volume;
(3) hermetically sealed can is sealed, vacuumize wherein, vacuum is-0.8Mpa to keep 20 minutes; Then be filled with wherein nitrogen pressurization, pressure is 0.8Mpa, keeps 20 minutes; 3 times so repeatedly; When vacuumizing and pressurizeing, to hermetically sealed can heating, temperature is 40 DEG C;
(4) Radix Glycyrrhizae powder step (4) being obtained to water content 60%, adds cellulase to carry out enzymolysis at 60 DEG C of low temperature dryings, and 6 hours time, the mass ratio of its cellulase and Radix Glycyrrhizae powder is 0.8g:50g, and the enzyme work of cellulase is 40000 u/g.
The sporoderm-broken rate that embodiment 3 processes gained Radix Glycyrrhizae is 97%.
The manufacturer of embodiment 1 ~ 3 cellulase used is: Lu Guang bio tech ltd, Shanghai.
Comparative example 1 ~ 3: get cordate houttuynia and pulverize 40 orders, get cortex albiziae and be crushed to 60 orders, extracting liquorice is crushed to 40 orders, processes without any other, and respectively as a comparison case 1 ~ 3.
Test example 1: smashing capability
Embodiment 1 ~ 3 and comparative example 1 ~ 3 are dried respectively at 60 ~ 70 DEG C, then get respectively 100g and put into atomizer and pulverize 5 minutes, the material obtaining is sieved, thereby obtain the distribution of particle sizes of every kind of material.Concrete data are shown in Table 1.
Table 1(unit: g)
Can see from the data of table 1, the smashing capability of embodiment is significantly improved than comparative example, and this shows that enzyme processing can improve the smashing capability of Chinese herbal medicine.
Test example 2: water leaching rate
Leaching refers to and utilizes suitable solvent dissolving method, the process from bulk drug (comprising animal, plant and mineral substance), solubility active ingredient being leached.It is a blanket important basic operation during Chinese medicine preparation is produced.The size of leaching rate is also the important indicator of Chinese herbal medicine result quality.
Water-soluble extractives determination method: hot dipping, get test sample accurately weighed, to put in conical flask, precision adds water, close plug, weighed weight, left standstill after 1 hour, connected reflux condensing tube, was heated to boiling, and kept micro-and boil 1 hour.After letting cool, take off conical flask, close plug, more weighed weight, water is supplied the weight of less loss, shakes up, with dry filter filtration.Precision measures filtrate, puts in the evaporating dish that is dried to constant weight, in water-bath after evaporate to dryness, in 105 DEG C dry 3 hours, put in drier rapid accurately weighed weight cooling 30 minutes, unless otherwise specified, calculate the content (%) of water-soluble extractives in test sample with dry product.
Condition determination adopts: get the material of 30g, in 37 DEG C of water, soak 5 hours.The data of the water leaching rate of embodiment 1 ~ 3 and comparative example 1 ~ 3 are as shown in table 2.
Table 2(unit: g)
Can see from the data of table 2, the water leaching rate of embodiment is significantly improved than comparative example, and this shows will be higher than non-enzyme processing sample through its water leaching rate of enzyme sample after treatment.
Claims (6)
1. a feeding Chinese herbal medicine pretreatment wall-breaking method, is characterized in that comprising the steps:
(1) Chinese herbal medicine powder was broken to 40 ~ 60 mesh sieves, obtained herbal powder;
(2) in the herbal powder after sieving, sprinkle water while stirring, making its water content is 85 ~ 90%, and moisture is uniformly dispersed in herbal powder; Herbal powder after watering is put into hermetically sealed can, and the volume of described powder natural packing accounts for 50 ~ 60% of hermetically sealed can volume;
(3) hermetically sealed can is sealed, vacuumize wherein, vacuum is-0.5Mpa ~-1.2Mpa to keep 15 ~ 20 minutes; Then be filled with wherein nitrogen pressurization, pressure is 0.5Mpa ~ 1.2Mpa, keeps 15 ~ 20 minutes; 3 ~ 4 times so repeatedly;
(4) herbal powder low temperature drying step (4) being obtained, to water content 60 ~ 70%, adds cellulase to carry out enzymolysis, 6 ~ 8 hours time.
2. feeding Chinese herbal medicine pretreatment wall-breaking method according to claim 1, while it is characterized in that step (3) vacuumizes and pressurizes, to hermetically sealed can heating, temperature is 25 ~ 40 DEG C.
3. feeding Chinese herbal medicine pretreatment wall-breaking method according to claim 2, is characterized in that the temperature heating to hermetically sealed can is higher, and the pressure vacuumizing is higher, and the pressure of pressurization is lower, and the retention time is shorter.
4. feeding Chinese herbal medicine pretreatment wall-breaking method according to claim 1, is characterized in that the mass ratio of cellulase described in step (4) and herbal powder is 0.6 ~ 0.8g:50g.
5. feeding Chinese herbal medicine pretreatment wall-breaking method according to claim 1, the enzyme work that it is characterized in that cellulase described in step (4) is 13000 ~ 40000 u/g.
6. feeding Chinese herbal medicine pretreatment wall-breaking method according to claim 1, the temperature that it is characterized in that low temperature drying described in step (4) is 40 ~ 60 DEG C.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106721140A (en) * | 2016-11-25 | 2017-05-31 | 周福弟 | It is a kind of raise feeder for goat and goat fatten method |
| CN110591891A (en) * | 2019-09-25 | 2019-12-20 | 广西中医药大学 | Little algae cell broken wall machine |
| CN111454767A (en) * | 2020-04-27 | 2020-07-28 | 合肥学院 | Method for extracting folium artemisiae argyi essential oil |
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| CN102552554A (en) * | 2011-12-23 | 2012-07-11 | 广州市娇兰化妆品有限公司 | Chinese medicinal extract with anti-allergic effect as well as preparation method and application thereof |
| CN103349637A (en) * | 2013-07-31 | 2013-10-16 | 广州市娇兰化妆品有限公司 | Compound traditional Chinese medicine extract with effects of whitening and moisturizing, preparation method and application thereof |
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2014
- 2014-06-18 CN CN201410271863.2A patent/CN104187012A/en active Pending
Patent Citations (3)
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| CN102552554A (en) * | 2011-12-23 | 2012-07-11 | 广州市娇兰化妆品有限公司 | Chinese medicinal extract with anti-allergic effect as well as preparation method and application thereof |
| CN103349637A (en) * | 2013-07-31 | 2013-10-16 | 广州市娇兰化妆品有限公司 | Compound traditional Chinese medicine extract with effects of whitening and moisturizing, preparation method and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106721140A (en) * | 2016-11-25 | 2017-05-31 | 周福弟 | It is a kind of raise feeder for goat and goat fatten method |
| CN110591891A (en) * | 2019-09-25 | 2019-12-20 | 广西中医药大学 | Little algae cell broken wall machine |
| CN111454767A (en) * | 2020-04-27 | 2020-07-28 | 合肥学院 | Method for extracting folium artemisiae argyi essential oil |
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