CN104173979A - Heat clearing and cold dispelling traditional Chinese medicine composition for cold cough and preparation method thereof - Google Patents

Abstract

The invention discloses a heat clearing and cold dispelling traditional Chinese medicine composition for cold cough. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 18-25 parts of yam, 6-12 parts of peppermint, 9-15 parts of ophiopogon root, 5-12 parts of Veronica sibirica, 6-12 parts of honeysuckle flower, 4-9 parts of anemarrhena rhizome, 5-15 parts of dahurian angelica, 2-6 parts of anemone, 3-9 parts of prepared liquorice root, 2-6 parts of ginger, 6-12 parts of Chinese date, 5-15 parts of purple perilla leaf, 3-12 parts of balloon flower root, 9-16 parts of peucedanum root, 9-13 parts of burdock fruit, 6-12 parts of schizonepeta spike, 4-9 parts of chastetree fruit, 3-6 parts of Adenophora trachelioides, 6-15 parts of notoperygium root, 4-14 parts of ledebouriella root, 6-15 parts of cocklebur fruit, 5-14 parts of forsythia fruit, 12-20 parts of radix isatidis, 5-12 parts of bupleurum root, 3-9 parts of scutellaria root, 5-12 parts of Lythrum salicaria and 6-18 parts of kudzu root. The traditional Chinese medicine composition is prepared based on the research of extensive literatures and clinical trials, and is remarkable in treatment effect.

Description

Chinese medicine composition and the preparation method of cold cough heat clearing away cold expelling

Technical field

The present invention relates to Chinese medicine field, particularly relate to a kind of Chinese medicine composition and preparation method of cold cough heat clearing away cold expelling.

Background technology

The generation of flu is empty mainly due to body, and resistance against diseases weakens, and when weather drastic change, human body is defended external work and can be adapted to, and pathogen is taken advantage of a weak point in opponent's defence and entered by fur, mouth and nose, causes that a series of lungs defend symptom, betides more winter.Flu is a kind of common disease, approximately has 70% by infecting virus, to cause.Generally within 1-3 days after being infected, just there will be nasal obstruction, sneeze, rhinorrhea, pharyngeal discomfort, tussicula, heating etc., temperature just differs.Flu is divided into the types such as wind and cold, wind heat, heat-damp in summer, exterior cold and interior heat on tcm clinical practice.Anemofrigid cold, general fever is lighter, does not perspire, and has and is afraid of cold performance of being afraid of cold, and flows in addition clear water nasal mucus simultaneously, and cough, sneeze are a burst of, the clear rare easy expectoration of expectorant, the symptom of thin white fur of tongue.Anemopyretic cold is due to evil criminal's table, the lung qi of wind heat become estranged.Symptoms is felt sick for heating is heavy, micro-, distending pain in the head, have antiperspirant, red swelling and pain of throat, cough, expectorant is sticky or yellow, nasal obstruction yellow thick nasal discharge, thirst and liking drink, the tip of the tongue limit are red, the micro-Huang of white and thin fur.Summer-heat damp cold main manifestations is heating, dizzy, distending pain, lassitude from head to foot, with the disease such as uncomfortable in chest, nauseating.Exterior cold and interior heat flu has another name called fire wrapped by cold, and, headache sticky, irritated mainly with fever with aversion to cold, cough and asthma, expectorant Huang is primary symptom.

Cough is the common sudden symptom of a kind of respiratory tract, cough is caused by inflammation, foreign body, physics or chemical irritation by trachea, bronchial mucosa or pleura, Closure states of glottis before this during cough, respiratory muscle shrinks, intrapulmonic pressure raises, then glottis opens, and pulmonary air is spouting, is conventionally accompanied by sound.Cough has the protective effect of removing respiratory tract foreign body and secretions.If cough does not stop, by acute, transfer to chronicly, usually to patient, bring larger misery, as uncomfortable in chest, itching throat, breathe etc.Cough is a very common symptom, and almost everyone lives through the worry of cough, and especially season in severe winter, a lot of old men, child and patient Lian Menye dare not go out, and have greatly affected quality of life.The reason of cough is comparatively complicated, comprises acute and chronic bronchitis, pneumonia, Respirovirus or antibacterial infection, cough variant asthma, upper respiratory tract cough syndrome etc.The cough being caused as acute bronchitis, pneumonia etc. by acute respiratory infection is generally acute cough, antibiotic therapy through a couple of days can be cured very soon, chronic cough as cough variant asthma often repeatedly outbreak and protracted course of disease, have a strong impact on patient's working and learning, even affect patient's quality of life.With regard to chronic cough, cough variant asthma is more more common than chronic bronchitis.Cough variant asthma is called allergic bronchitis or allergic cough in the past, to take chronic cough as unique clinical symptoms, can occur in any age level, but more easily occur in child and women, main manifestations is zest, the refractory dry cough of outbreak repeatedly, and usually cough is more than for no reason at all, and sustainable some months is the several years even, very easily mistaken diagnosis is that bronchitis is used various antibiotic and cough suppressing medicine, but is often of no curative effect.Cough variant asthma is also usually with the symptom of the allergic rhinitis such as sneeze, snivel and nasal obstruction frequently, at asthma commitment, nearly 5-6% be take persistence cough as cardinal symptom, mostly occur in night or morning, normal for irritable cough, be now often misdiagnosed as bronchitis.The current pathogeny to cough variant asthma, Most scholars thinks that with the mechanism of typical asthma be consistent, is a kind of airway allergy inflammation.The order of severity that is only course advancement degree difference or airway inflammation differs.

Cough is the autoprotection mechanism that air flue mucosa is removed external substance or mucus, secretions.Cough receptor comprises two large classes: A δ fiber, and belong to fast adjusting and extend receptor, mainly concentrate on knuckle, the stimulation of slightly being touched or suck dust reacts; C fiber, that its tip is positioned at is pharyngeal, bronchial tree and alveolar, mainly to chemical irritation thing, as captopril, some inflammatory mediator (as Kallidin I) etc. reacts, also be subject to the stimulation of some mechanical force, the release of the contained neuropeptide material of C fiber (as Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) can strengthen the activation of A δ fiber again simultaneously.After sensor is upset, by vagus nerve, import medullary substance coughing centre into, and then by nervus centrifugalis, make diaphram, Intercostal muscle, pharynx produce corresponding cough action.

At present, the Chinese medicine for the treatment of cold cough has a lot, but specific aim is not strong, for the problems referred to above, the patent documentation of publication number CN103157030A (application number 201310086504.5) discloses a kind of Chinese medicine composition of coughing after infantile common cold for the treatment of, this Chinese medicine composition is the ingredients by following weight portion: Folium Mori 3-9 part, Flos Chrysanthemi 3-9 part, Radix Platycodonis 3-9 part, Fructus Forsythiae 4-14 part, Semen Armeniacae Amarum (parched) 3-9 part, Rhizoma Phragmitis 15-25 part, Flos Lonicerae 10-20 part, Folium Isatidis 7-17 part, Radix Peucedani 3-9 part, Bulbus Fritillariae Thunbergii 4-14 part, Radix Asteris 3-9 part, Flos Farfarae 3-9 part, Bulbus Lilii 3-9 part, Radix Glycyrrhizae 2-6 part.Publication number CN 103860983A(application number 201210524569.9) patent documentation discloses a kind of Chinese medicine that is used for the treatment of the cough that causes of flu, and it is to be made by the raw material of following parts by weight: Cortex Mori 10-20, Radix Scutellariae 10-20, Radix Stemonae 10-20, Radix Asteris 10-20, Radix Glycyrrhizae 5-10, Herba Schizonepetae 10-20, Radix Saposhnikoviae 10-20, Rhizoma Et Radix Notopterygii 10-20, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10-20, Radix Peucedani 10-20, Poria 10-20, Rhizoma Chuanxiong 10-20, Radix Platycodonis 10-20, Pericarpium Citri Reticulatae 10-20.Publication number CN 103961612A(application number 201410137943.9) patent documentation discloses a kind of flu for the treatment of, cough, pharyngitis, asthma, the Chinese and Western pill of pulmonary carcinoma, raw material by following weight proportion is made: Guangdong Herba Artemisiae Anomalae (four seasons dish) 300g-600g, Herba Scutellariae Barbatae 200g-400g, Ganoderma 200g-400g, Herba Taraxaci 200g-400g, Fructus Schisandrae Chinensis 150g-300g, Rhizoma Atractylodis Macrocephalae 150g-300g, XIAKUQIU 150g-300g, Herba Agrimoniae 150g-300g, Foliole banyan dips dry 150g-300g, Radix Glycyrrhizae dips dry 150g-300g, Radix Scutellariae 100g-200g, Fructus Anisi Stellati 100g-200g, Radix Stemonae 100g-200g, Fructus Aurantii Immaturus 100g-200g, Radix Angelicae Dahuricae 100g-200g, Poria 100g-200g, Western medicine (acetylspiramycin tablet, terbutaline sulphate sheet, tea Xin Namin sheet) every object dosage is 50% of Western medicine common dose during proportioning.

The prior art that comprises above-mentioned patent documentation also comes with some shortcomings, and the specific aim of most of technology is all indefinite, and curative effect is undesirable, and much medicine easily allows patient produce dependent form, needs further to improve and improve.

Summary of the invention

For the deficiencies in the prior art, one of object of the present invention is to provide a kind of Chinese medicine composition of preparing simple, taking convenience, portable cold cough heat clearing away cold expelling, this Chinese medicine composition is formulated in conjunction with clinical practice for many years, evident in efficacy to various acute and chronic cold cough diseases.Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

The Chinese medicine composition of cold cough heat clearing away cold expelling, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Dioscoreae 18-25 part; Herba Menthae 6-12 part; Radix Ophiopogonis 9-15 part; Leptandra sibirica 5-12 part; Flos Lonicerae 6-12 part; Rhizoma Anemarrhenae 4-9 part; Radix Angelicae Dahuricae 5-15 part; Rhizoma Anemones Altaicae 2-6 part; Radix Glycyrrhizae Preparata 3-9 part; Rhizoma Zingiberis Recens 2-6 part; Fructus Jujubae 6-12 part; Folium Perillae 5-15 part; Radix Platycodonis 3-12 part; Radix Peucedani 9-16 part; Fructus Arctii 9-13 part; Herba Schizonepetae 6-12 part; Fructus Viticis 4-9 part; Radix Adenophorae Trachelioidis 3-6 part (preferred ， Radix Adenophorae Trachelioidis 3.5-5.5 part; 3.8 parts of the ， Radix Adenophorae Trachelioidis being more preferably); Rhizoma Et Radix Notopterygii 6-15 part; Radix Saposhnikoviae 4-14 part; Fructus Xanthii 6-15 part; Fructus Forsythiae 5-14 part; Radix Isatidis 12-20 part; Radix Bupleuri 5-12 part; Radix Scutellariae 3-9 part; Herba Lythri Salicariae 5-12 part; Radix Puerariae 6-18 part.

The Chinese medicine composition of cold cough heat clearing away cold expelling, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Dioscoreae 20-23 part; Herba Menthae 8-10 part; Radix Ophiopogonis 11-13 part; Leptandra sibirica 7-10 part; Flos Lonicerae 8-10 part; Rhizoma Anemarrhenae 5-8 part; Radix Angelicae Dahuricae 8-12 part; Rhizoma Anemones Altaicae 3-5 part; Radix Glycyrrhizae Preparata 5-7 part; Rhizoma Zingiberis Recens 3-5 part; Fructus Jujubae 8-10 part; Folium Perillae 8-12 part; Radix Platycodonis 6-9 part; Radix Peucedani 11-14 part; Fructus Arctii 10-12 part; Herba Schizonepetae 8-10 part; Fructus Viticis 5-8 part; Radix Adenophorae Trachelioidis 4-5 part; Rhizoma Et Radix Notopterygii 9-12 part; Radix Saposhnikoviae 7-11 part; Fructus Xanthii 9-12 part; Fructus Forsythiae 8-11 part; Radix Isatidis 15-17 part; Radix Bupleuri 7-10 part; Radix Scutellariae 5-7 part; Herba Lythri Salicariae 7-10 part; Radix Puerariae 9-15 part.The Chinese medicine composition of cold cough heat clearing away cold expelling, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from :22 parts of Rhizoma Dioscoreaes; 9 parts of Herba Menthaes; 12 parts of Radix Ophiopogonis; 8 parts of Leptandra sibiricas; 9 parts of Flos Loniceraes; 6 parts of the Rhizoma Anemarrhenaes; 10 parts of the Radixs Angelicae Dahuricae; 4 parts of Rhizoma Anemones Altaicaes; 6 parts of Radix Glycyrrhizae Preparatas; 4 parts, Rhizoma Zingiberis Recens; 9 parts, Fructus Jujubae; 10 parts of Folium Perillaes; 8 parts of Radix Platycodoniss; 12 parts of Radix Peucedanis; 11 parts of Fructus Arctiis; 9 parts of Herba Schizonepetaes; 6 parts of Fructus Viticises; 4.5 parts of Radix Adenophorae Trachelioidis; 11 parts of Rhizoma Et Radix Notopterygiis; 9 parts of Radix Saposhnikoviaes; 11 parts of Fructus Xanthii; 10 parts of Fructus Forsythiaes; 16 parts of Radix Isatidis; 8 parts of Radix Bupleuri; 6 parts of Radix Scutellariaes; 8 parts of Herba Lythri Salicariae; 12 parts of Radix Puerariaes.

The present invention also provides the preparation method of above-mentioned Chinese medicine composition being made to pharmaceutically acceptable powder, decoction, unguentum and pill.

The preparation method of the Chinese medicine composition composition powders of described cold cough heat clearing away cold expelling, step is as follows:

(1) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(2) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, together with step (1) gains, be ground into altogether fine powder, cross 140-180 mesh sieve (preferably 150-170 mesh sieve, is more preferably 160 mesh sieves);

(3) Herba Menthae, Radix Ophiopogonis, Leptandra sibirica, Flos Lonicerae, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens, Folium Perillae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Fructus Forsythiae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae, Herba Lythri Salicariae and Radix Puerariae are Tumblied Dry, being placed in pulverizer pulverizes, cross 160-200 mesh sieve (preferably 170-190 mesh sieve, is more preferably 180 mesh sieves);

(4) by the fine powder mixing and stirring of step (2)-(3) gained, the powder that gets product, carries out sterile packaged by the specification pharmaceutically accepted.

Instructions of taking: get 8-10g at every turn, be placed in tea bag, soak by the warm water of 50 ℃ of left and right, take after meal every day 3 times, 2 days courses for the treatment of half an hour.

The preparation method of the Chinese medicine composition decoction of described cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) step (5) gained filtrate is added to ethanol, ethanol consumption is 0.5-1.5 times (preferably 0.75-1.25 times of filtrate weight, be more preferably 1 times), standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filters, filtrate recycling ethanol alcohol are also concentrated into 3/4-1/2 (the preferred 2/3-7/12 of original volume, be more preferably 5/8), sterile packaged, obtains decoction.

Instructions of taking: each 15-20ml, with the warm water delivery service of 35 ℃ of left and right, takes every day 2-3 time, 2 days courses for the treatment of after meal half an hour.

The preparation method of the Chinese medicine composition unguentum of described cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate to standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filter, filtrate recycling ethanol is also condensed into the thick paste that relative density is 1.2-1.4 (preferably 1.25-1.35, is more preferably 1.3) at 45 ℃, obtains unguentum.

The preparation method of above-mentioned Chinese medicine composition unguentum, step (6) ethanol consumption is 0.5-1.5 times (preferably 0.75-1.25 doubly, is more preferably 1 times) of filtrate quality.

Instructions of taking: get 6-10ml at every turn, take after the warm water dilution with 35 ℃ of left and right, take after meal every day 3 times, 2 days courses for the treatment of half an hour.

The preparation method of the Chinese medicine composition pill of described cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate, standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filters, filtrate recycling ethanol is also condensed into the thick paste that relative density is 1.2-1.4 (preferred 1.25-1.35 at 45 ℃, be more preferably 1.3), be modulated into loose soft material of light pressure, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder.

(7) Mel is placed in pot, with slow fire, tempers, wait Mel to endure to thick, then mix the medicated powder of step (6) gained, fully mix into ointment thoroughly, by traditional Chinese medical science tradition pill method, make pill, obtain pill.

The preparation method of above-mentioned Chinese medicine composition pill, step (6) ethanol consumption is 0.5-1.5 times (preferably 0.75-1.25 doubly, is more preferably 1 times) of filtrate quality.

The preparation method of above-mentioned Chinese medicine composition pill, step (7) is joined 0.4-0.6 kilogram of Mel (preferably per kilogram medicated powder is joined 0.45-0.55 kilogram of Mel, is more preferably per kilogram medicated powder and joins 0.5 kilogram of Mel) by per kilogram medicated powder.

Instructions of taking: each 10-15 ball, with the warm boiled water of 35 ℃ of left and right, take after meal every day 3 times, 2 days courses for the treatment of half an hour.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.Dry rhizome for Dioscoreaceae plant Rhizoma Dioscoreae.There is spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating, for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.

Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.Dry aerial parts for labiate Herba Menthae.There is dispelling wind-heat, refresh oneself, the effect of rash.For anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, order skin ulcer, rubella, measles, breast side of body feeling of distension and oppression.

Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature.GUIXIN, lung, stomach warp.Another name Radix Ophiopogonis is the liliaceous plant dried root of Radix Ophiopogonis.There is YIN nourishing and the production of body fluid promoting, the effect that lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Leptandra sibirica: acrid in the mouth, micro-hardship, cold in nature.Root and herb for Scrophulariaceae Herba veronicastri villosuli platymiscium Leptandra sibirica.Herb contains phenolic acids: Hesperetic acid, 3,4-dimethoxy cinnamic acid.Also contain 3-O-acetyloleanolic acid, PEARLITOL 25C daucosterol etc.The sugary glycoside of root: glycosides in rice, aucubin, the different Resina Ferulae acyl of 6-deoxidation-8-Harpagide etc.Seed contains fatty acid: brown Palm acid, stearic acid, oleic acid, linoleic acid etc.There is expelling wind and removing dampness, the effect of heat-clearing and toxic substances removing.For cold anemopyretic, laryngopharynx swelling and pain.Parotitis, rheumatic arthralgia, Serpentis hinders worm.

Flos Lonicerae: sweet in the mouth, cold in nature.Return lung, the heart, stomach warp.For caprifoliaceae plant dry flower or the first flower of opening of band of Radix Ophiopogonis.There is heat-clearing and toxic substances removing, the effect of wind-heat dissipating.For carbuncle furuncle. sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.

The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Dry rhizome for the liliaceous plant Rhizoma Anemarrhenae.There is clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.

The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Return stomach, large intestine, lung meridian.Dry root for the samphire Radix Angelicae Dahuricae or Radix angelicae dahuricae.There is loose wind dehumidifying, understand things pain-stopping, the effect of detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.

Rhizoma Anemones Altaicae: acrid in the mouth, warm in nature.GUIXIN, liver, spleen channel.Rhizome for Ranunculaceae thimbleweed anemone altaica.Rhizome fatty acids: Palmic acid, succinic acid, 5-hydroxylevulinic acid, hexadecanoic acid and 9,12-octadecadienoic acid, Anemonin etc.Have waking up the patient from unconsciousness by dissipating phlegm, expelling wind and removing dampness, helps digestion and is amusing, the effect of removing toxic substances.For calentura coma, epilepsy, deafness with qi stagnation, dreaminess is forgetful, rheumatic arthralgia, gastral cavity uncomfortable in chest is swollen, carbuncle, scabies.

Radix Glycyrrhizae Preparata: sweet in the mouth, property is flat.GUIXIN.Lung, spleen, stomach warp.Preparation process product for Radix Glycyrrhizae.There is Anew Issue Plate stomach function regulating, the effect of Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.

Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature.Return lung, spleen, stomach warp.Fresh rhizome for zingiber.There is the cold expelling of inducing sweat, warming middle-JIAO to arrest vomiting, the effect of preventing phlegm from forming and stopping coughing.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough.

Fructus Jujubae: sweet in the mouth, warm in nature.Return spleen, stomach warp.Dry mature fruit for Rhamnaceae plant Fructus Jujubae.There is invigorating the spleen and replenishing QI, the effect of nourishing blood to tranquillize the mind.For the empty lack of appetite of board, weak loose stool, woman hysteria.

Folium Perillae: acrid in the mouth, warm in nature.Return lung, spleen channel.Dried leaves or band twig for labiate Folium Perillae.There is the cold expelling of inducing sweat, the effect of relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy, fish Eriocheir sinensis is poisoning.

Radix Platycodonis: bitter in the mouth, pungent, property is flat.Return lung meridian.Dry root for Campanulaceae Radix Platycodonis.Have lung qi dispersing, sore-throat relieving, eliminates the phlegm, the effect of evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.

Radix Peucedani: bitter in the mouth, pungent, cold nature.Return lung meridian.Dry root for samphire Peucedanum praeruptorum DUNN.There is loose wind heat clearing away, the effect of lowering the adverse-rising QI to resolve phlegm.For cough due to pathogenic wind-heat's abundant expectoration, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.

Fructus Arctii: acrid in the mouth, hardship, cold in nature.Attach to the lung and stomach meridians.Dry mature fruit for feverfew Fructus Arctii.There is dispelling wind and heat pathogens, lung qi dispersing rash, the effect of resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, the cheek erysipelas of itching, carbuncle sore tumefacting virus.

Herba Schizonepetae: acrid in the mouth, slightly warm in nature.Return lung, Liver Channel.Dry spica for labiate Herba Schizonepetae.There is the loose wind that induces sweat, the effect of rash.For flu, headache, measles, rubella, skin infection from the beginning of.

Fructus Viticis: acrid in the mouth, hardship, cold nature.Return bladder, liver, stomach warp.Dry mature fruit for Verbenaceae Vitex rotundifolia or wild pepper.There is dispelling wind and heat pathogens, the clear sharp head's effect.For anemopyretic cold headache, gingivitis, the many tear of conjunctival congestion, poor vision, has a dizzy spell.

Radix Adenophorae Trachelioidis: taste is dry, cold in nature.Return lung, spleen channel.Root for campanulaceae Lady bell plant Radix Adenophorae Trachelioidis, slender lobule Radix Adenophorae Trachelioidis.There is moistening the lung and resolving the phlegm, the effect of heat-clearing and toxic substances removing.For xeropulmonary cough, laryngopharynx swelling and pain, quenches one's thirst, furuncle carbuncle sore, drug intoxication.

Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Dry rhizome and root for samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.There is cold expelling, dispel the wind, dehumidifying, the effect of pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.

Radix Saposhnikoviae: acrid in the mouth, sweet, warm in nature.Return bladder, liver, spleen channel.Dry root for umbelliferae Saposhnikovia divaricata.Have inducing diaphoresis to dispel wind, victory is wet, the effect of relieving convulsion.For headache due to common cold. rheumatic arthralgia, rubella pruritus, tetanus.

Fructus Xanthii: acrid in the mouth, hardship, warm in nature.Return lung meridian.Fruit for the drying and ripening band involucre of feverfew Herba Xanthii.There is loose wind dehumidifying, the effect of clearing the nasal passage.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.

Fructus Forsythiae: bitter in the mouth, cold nature.Return lung, the heart, small intestine meridian.Dry fruit for Oleaceae plants Fructus Forsythiae.There is heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.

Radix Isatidis: bitter in the mouth, cold in nature.GUIXIN, stomach warp.Dry root for cruciferae isatis.There is heat-clearing and toxic substances removing, the effect of removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.

Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.Dry root for umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..There is reconciling superficies and interior, soothing the liver, the effect of yang invigorating.For cold, fever. alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.

Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Dry root for labiate Radix Scutellariae.There is heat clearing and damp drying, rush down people's removing toxic substances, hemostasis, antiabortive effect.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.

Herba Lythri Salicariae: bitter in the mouth, cold in nature.Having another name called Purple Loosestrife, Herba pteridis vittatae, careless to tooth, is the herb of Lythraceae Lythrum plant Herba Lythri Salicariae.Herb is containing Salicarin, choline, gallotannin, orientin, chlorogenic acid etc.According to modern pharmacological research, find, this medical instrument has blood sugar lowering, antibacterial, heat-clearing and toxic substances removing, anastaltic effect, for hyperglycemia, spits blood, and epistaxis, has loose bowels, and skin infection festers etc.

Radix Puerariae: sweet in the mouth, pungent, cool in nature.Return spleen, stomach warp.For the dry root of legume pueraria lobata, practise and claim Herba Gelsemii Elegantis.There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, the effect of yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.

The Chinese medicine composition that the present invention treats cold cough heat clearing away cold expelling has to induce sweat and dries, QI invigorating cough-relieving, and the effect of relieving cough and resolving phlegm, can effectively treat cold cough.The present invention can avoid life-time service medicine therapy to tend to produce various side effect and dependency in addition, and draws materials as food common in daily life, cheap.

Technical advantage of the present invention is mainly reflected in:

1. the present invention can avoid life-time service medicine therapy to tend to produce various side effect and dependency.

2. the principle of medicament of the present invention based on traditional Chinese medical herbal treatment, is to make on the basis of having studied lot of documents, pharmacology work and clinical trial, and effect is remarkable.

3. this medicament selected materials great majority are Chinese medicine material, have no side effect, and have advantages of nontoxic no pain, have avoided the hardship of having an injection, taking medicine.

4. medical material medicine source is easy to get, with low cost, can not bring large financial burden to patient.

The specific embodiment

Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not limited to this.

embodiment 1the Chinese medicine composition of cold cough heat clearing away cold expelling, takes off the primary raw material of stating weight proportion and is prepared from (getting 20g for every part): 18 parts of Rhizoma Dioscoreaes; 6 parts of Herba Menthaes; 9 parts of Radix Ophiopogonis; 5 parts of Leptandra sibiricas; 6 parts of Flos Loniceraes; 4 parts of the Rhizoma Anemarrhenaes; 5 parts of the Radixs Angelicae Dahuricae; 2 parts of Rhizoma Anemones Altaicaes; 3 parts of Radix Glycyrrhizae Preparatas; 2 parts, Rhizoma Zingiberis Recens; 6 parts, Fructus Jujubae; 5 parts of Folium Perillaes; 3 parts of Radix Platycodoniss; 9 parts of Radix Peucedanis; 9 parts of Fructus Arctiis; 6 parts of Herba Schizonepetaes; 4 parts of Fructus Viticises; 3 parts of Radix Adenophorae Trachelioidis; 6 parts of Rhizoma Et Radix Notopterygiis; 4 parts of Radix Saposhnikoviaes; 6 parts of Fructus Xanthii; 5 parts of Fructus Forsythiaes; 12 parts of Radix Isatidis; 5 parts of Radix Bupleuri; 3 parts of Radix Scutellariaes; 5 parts of Herba Lythri Salicariae; 6 parts of Radix Puerariaes.

The preparation method of the Chinese medicine composition composition powders of above-mentioned cold cough heat clearing away cold expelling, step is as follows:

(1) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(2) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, together with step (1) gains, be ground into fine powder, cross 160 mesh sieves;

(3) Herba Menthae, Radix Ophiopogonis, Leptandra sibirica, Flos Lonicerae, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens, Folium Perillae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Fructus Forsythiae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae, Herba Lythri Salicariae and Radix Puerariae are Tumblied Dry, be placed in pulverizer and pulverize, cross 180 mesh sieves;

(4) by the fine powder mixing and stirring of step (2)-(3) gained, the powder that gets product, carries out sterile packaged by the specification pharmaceutically accepted.

Instructions of taking: get 10g at every turn, be placed in tea bag, soak by the warm water of 50 ℃ of left and right, take after meal every day 3 times, 2 days courses for the treatment of half an hour.

model case oneold XX, female, 62 years old, people from Dezhou City Shandong Province.On August 1st, 2011, because flu causes cough, throat pain, flushing while coughing, expectorant is few, bitterly draw two sides of body while coughing, T37.5 ℃, P90 beat/min, BP120/70mmHg, pharyngeal congestion, not enlargement of bilateral amygdala, two pulmonary respiration sounds are clear, rule, together without noise, after hospital treatment, turns into repeatedly, the medicine that uses various relieving cough and resolving phlegm over three months, symptom has no improvement.When the state of an illness continues to 2 wheat harvesting period, pharyngeal congestion edema, antiadoncus, rabat shows two increased bronchovascular shadows, and just has many years ago chronic pharyngitis and frequent cough medical history, just aggravation in recent years, develops into cureless disease.

Afterwards, asked about the Chinese medicine composition of cold cough heat clearing away cold expelling of the present invention, take the Chinese medicine composition composition powders of embodiment 1 gained cold cough heat clearing away cold expelling after 1 course for the treatment of, the symptom of laryngopharynx swelling and pain, dizziness headache obviously alleviates, and the symptom of cough also alleviates to some extent.Adhere to that the Chinese medicine composition composition powders of taking embodiment 1 gained cold cough heat clearing away cold expelling is after 1 course for the treatment of, the swell symptom of sense, the sense of throat congestion and swelling pain, nasal obstruction of headache all disappears, and only has slight cough.Continue to take the Chinese medicine composition composition powders of embodiment 1 gained cold cough heat clearing away cold expelling and consolidate 1 course for the treatment of, the symptom of cough also disappears substantially, and it is fine that complexion becomes.In the following up a case by regular visits to of later stage, learn recovery from illness.

embodiment 2the Chinese medicine composition of cold cough heat clearing away cold expelling, takes off the primary raw material of stating weight proportion and is prepared from (every part of 10g): 20 parts of Rhizoma Dioscoreaes; 8 parts of Herba Menthaes; 11 parts of Radix Ophiopogonis; 7 parts of Leptandra sibiricas; 8 parts of Flos Loniceraes; 5 parts of the Rhizoma Anemarrhenaes; 8 parts of the Radixs Angelicae Dahuricae; 3 parts of Rhizoma Anemones Altaicaes; 5 parts of Radix Glycyrrhizae Preparatas; 3 parts, Rhizoma Zingiberis Recens; 8 parts, Fructus Jujubae; 8 parts of Folium Perillaes; 6 parts of Radix Platycodoniss; 11 parts of Radix Peucedanis; 10 parts of Fructus Arctiis; 8 parts of Herba Schizonepetaes; 5 parts of Fructus Viticises; Radix Adenophorae Trachelioidis 4-part; 9 parts of Rhizoma Et Radix Notopterygiis; 7 parts of Radix Saposhnikoviaes; 9 parts of Fructus Xanthii; 8 parts of Fructus Forsythiaes; 15 parts of Radix Isatidis; 7 parts of Radix Bupleuri; 5 parts of Radix Scutellariaes; 7 parts of Herba Lythri Salicariae; 9 parts of Radix Puerariaes.

The preparation method of the Chinese medicine composition decoction of above-mentioned cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 100 mesh sieves, then by suitable quantity of water, soak, be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 6min, packs air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 60 mesh sieves, gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 2 days, be placed in marmite, add water, moderate heat decocts 30 minutes;

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 40 minutes at every turn, twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) step (5) gained filtrate is added to ethanol, ethanol consumption is 15 times of filtrate weight, standing 5 hours, filter, and filtrate recycling ethanol alcohol are also concentrated into 1/2 of original volume, and sterile packaged, obtains decoction.

Instructions of taking: each 20ml, with the warm water delivery service of 35 ℃ of left and right, takes every day 3 times, 2 days courses for the treatment of after meal half an hour.

model case twoopen XX, man, 68 years old, Accessories during Binzhou, Shandong Province from Huimin County.Because suffering from cold, occur ictally panting, laryngopharynx swelling and pain, gurgling with sputum, certainly take coldrex, symptom has no obviously and alleviates, uncomfortable in chest, cough, cough up yellow sticky expectorant, difficulty in expectorating, body temperature and blood pressure are normal, audible and wheezing sound between not good enough, the orthopnea larynx of spirit, two lungs are covered with wheezing sound, by X line, show that two lungs become excessive inflated condition, toward there being bronchial asthma 20 years, obstinate is used the treatment of antiinflammatory Apophlegmatisant, all without positive effect at every turn while showing effect.Each outbreak is got up one month at least, at most the several months, continues for two more than ten years, lives among misery for a long time.

Its children hear that the curative effect of Chinese medicine composition of cold cough heat clearing away cold expelling of the present invention is fine, so bought 1 the course for the treatment of embodiment 2 gained cold cough heat clearing away cold expelling Chinese medicine composition decoction, taken after this 1 course for the treatment of, the symptom of headache feeling of fullness in the head, laryngopharynx swelling and pain is just eased.See this curative effect, bought again 1 the course for the treatment of embodiment 2 gained cold cough heat clearing away cold expelling Chinese medicine composition decoction, after having taken, laryngopharynx swelling and pain, the transference cure such as uncomfortable in chest, cough also obviously alleviates, 2 courses for the treatment of of Chinese medicine composition decoction of continuing to take embodiment 2 gained cold cough heat clearing away cold expelling, various malaise symptoms all disappear.Later stage learns without recurrence in following up a case by regular visits to.

embodiment 3the Chinese medicine composition of cold cough heat clearing away cold expelling, takes off the primary raw material of stating weight proportion and is prepared from (getting 5g for every part): 23 parts of Rhizoma Dioscoreaes; 10 parts of Herba Menthaes; 13 parts of Radix Ophiopogonis; 10 parts of Leptandra sibiricas; 10 parts of Flos Loniceraes; 8 parts of the Rhizoma Anemarrhenaes; 12 parts of the Radixs Angelicae Dahuricae; 5 parts of Rhizoma Anemones Altaicaes; 7 parts of Radix Glycyrrhizae Preparatas; 5 parts, Rhizoma Zingiberis Recens; 10 parts, Fructus Jujubae; 12 parts of Folium Perillaes; 9 parts of Radix Platycodoniss; 14 parts of Radix Peucedanis; 12 parts of Fructus Arctiis; 10 parts of Herba Schizonepetaes; 8 parts of Fructus Viticises; 5 parts of Radix Adenophorae Trachelioidis; 12 parts of Rhizoma Et Radix Notopterygiis; 11 parts of Radix Saposhnikoviaes; 12 parts of Fructus Xanthii; 11 parts of Fructus Forsythiaes; 17 parts of Radix Isatidis; 10 parts of Radix Bupleuri; 7 parts of Radix Scutellariaes; 10 parts of Herba Lythri Salicariae; 15 parts of Radix Puerariaes.The preparation method of the Chinese medicine composition unguentum of above-mentioned cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 100 mesh sieves, then by suitable quantity of water, soak, be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 6min, packs air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 60 mesh sieves, gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 2 days, be placed in marmite, add water, moderate heat decocts 30 minutes;

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 40 minutes at every turn, twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate, standing 5 hours, filter, filtrate recycling ethanol to be condensed into relative density at 45 ℃ be 1.3 thick paste, obtains unguentum.

model case threeking XX, female, 18 years old, student, people from Lixia District, Jinan City, Shandong Province.Because there is panting, cough, cough up the sticky expectorant of white, companion's vomiting and nausea in the flu of suffering from cold.Be in and use CHUANBEI PIPA GAO and multiple preventing phlegm from forming and stopping coughing medicine without improvement, disease opinion is panted, coughs serious, and spirit is not good enough, and blood pressure and body temperature are normal, 88 beats/min of hearts rate, and routine blood test is normal, and rabat shows: the bright increase of two lungs, two lower field textures increase.In hospital, use Western medicine and hormone therapy without being clearly better.

Its mother has heard that unintentionally the Chinese medicine composition of cold cough heat clearing away cold expelling of the present invention is evident in efficacy, so buy the Chinese medicine composition unguentum of the embodiment 3 gained cold cough heat clearing away cold expelling of 1 course for the treatment of, after having taken, the symptom of slight chill, cough, headache, nasal obstruction, the turbid tears of stream, pharyngalgia is all eased.See this curative effect, so buy again 1 course for the treatment of, consolidate, taken rear various malaise symptoms and disappeared, self-induction recovery from illness.

embodiment 4the Chinese medicine composition of cold cough heat clearing away cold expelling, takes off the primary raw material of stating weight proportion and is prepared from (getting 10g for every part): 22 parts of Rhizoma Dioscoreaes; 9 parts of Herba Menthaes; 12 parts of Radix Ophiopogonis; 8 parts of Leptandra sibiricas; 9 parts of Flos Loniceraes; 6 parts of the Rhizoma Anemarrhenaes; 10 parts of the Radixs Angelicae Dahuricae; 4 parts of Rhizoma Anemones Altaicaes; 6 parts of Radix Glycyrrhizae Preparatas; 4 parts, Rhizoma Zingiberis Recens; 9 parts, Fructus Jujubae; 10 parts of Folium Perillaes; 8 parts of Radix Platycodoniss; 12 parts of Radix Peucedanis; 11 parts of Fructus Arctiis; 9 parts of Herba Schizonepetaes; 6 parts of Fructus Viticises; 4.5 parts of Radix Adenophorae Trachelioidis; 11 parts of Rhizoma Et Radix Notopterygiis; 9 parts of Radix Saposhnikoviaes; 11 parts of Fructus Xanthii; 10 parts of Fructus Forsythiaes; 16 parts of Radix Isatidis; 8 parts of Radix Bupleuri; 6 parts of Radix Scutellariaes; 8 parts of Herba Lythri Salicariae; 12 parts of Radix Puerariaes.

The preparation method of the Chinese medicine composition pill of above-mentioned cold cough heat clearing away cold expelling, step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 100 mesh sieves, then by suitable quantity of water, soak, be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 6min, packs air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 60 mesh sieves, gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 2 days, be placed in marmite, add water, moderate heat decocts 30 minutes;

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 40 minutes at every turn, twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate, standing 5 hours, filter, filtrate recycling ethanol to be condensed into relative density at 45 ℃ be 1.3 thick paste, is modulated into loose soft material of light pressure, crosses 100 mesh sieves, dries, and pulverizes, and obtains medicated powder.

(7) Mel is placed in pot, with slow fire, tempers, wait Mel to endure to thick, then mix the medicated powder of step (6) gained, fully mix into ointment thoroughly, by traditional Chinese medical science tradition pill method, make pill, obtain pill.

Instructions of taking: each 15 balls, with the warm boiled water of 35 ℃ of left and right, take after meal every day 3 times, 2 days courses for the treatment of half an hour.

test examplethe clinical practice of the Chinese medicine composition pill of embodiment 4 gained cold cough heat clearing away cold expelling: in April, 2010-2012 year April, screen 200 routine cold cough patients in 3 hospitals, women's 100 examples wherein, male's 100 examples.Test 2 weeks before, carries out Continuous Observation to this crowd, records symptom and variation, is divided at random two groups of experimental group and matched group.Using method is: experimental group is taken the Chinese medicine composition pill of embodiment 4 gained cold cough heat clearing away cold expelling, and each 15 balls, with the warm boiled water of 35 ℃ of left and right, are taken after meal half an hour, every day 3 times, 2 days courses for the treatment of; Matched group is taken other medicine (as GANMAO RUANJIAONANG and Folium Eriobotryae cough syrup), takes half an hour after meal, and every day 3 times, each 1 capsule and 10ml Folium Eriobotryae cough syrup, with the warm boiled water of 35 ℃ of left and right.Curative effect determinate standard: cure: drug administration after 3 courses for the treatment of malaise symptoms disappear completely; Effective: drug administration after 3 courses for the treatment of malaise symptoms alleviate or part disappears, energy and muscle power strengthen; Invalid: drug administration is the recurrence of unchanged or later stage of malaise symptoms after 3 courses for the treatment of.Wherein, effectively comprise healing and effective.Result is as shown in table 1.

Table 1

Therapeutic effect: as can be seen from Table 1, take the cure rate of Chinese medicine composition pill of embodiment 4 gained cold cough heat clearing away cold expelling up to 83%, effective percentage 98%, inefficiency is only 2%; And the cure rate of taking other drug only 36%, effective percentage only has 86%, and inefficiency is up to 14%.Can find out: the successful of taking the Chinese medicine composition pill of embodiment 4 gained cold cough heat clearing away cold expelling is better than taking the effect of other cold medicines.

                            

Table 2

the ratio that during medication, cardinal symptom is eased (XX% represents)

By table 2, also found out significantly, in the alleviation of various symptoms, use the Chinese medicine composition pill of the embodiment of the present invention 4 gained cold cough heat clearing away cold expelling more remarkable than the effect of taking other drug.Wherein, take 1 course for the treatment of of Chinese medicine composition pill of the embodiment of the present invention 4 gained cold cough heat clearing away cold expelling, more than 51% patient feels to take a turn for the better to some extent, and malaise symptoms improves, and matched group only has 32% patient to alleviate to some extent; 2 courses for the treatment of of Chinese medicine composition pill of taking the embodiment of the present invention 4 gained cold cough heat clearing away cold expelling, more than 72% patient feels to take a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen, and matched group only has 56% patient to alleviate to some extent; Take 3 courses for the treatment of of Chinese medicine composition pill of the embodiment of the present invention 4 gained cold cough heat clearing away cold expelling, more than 97% patient feels to take a turn for the better to some extent, appetite obviously strengthens, malaise symptoms improves or disappears, spirit, muscle power strengthen, some patients were self-induction is without malaise symptoms, and matched group only has 78% patient to alleviate to some extent.Can infer the Chinese medicine composition better efficacy of cold cough heat clearing away cold expelling of the present invention, be a kind of medicament of more satisfactory treatment cold cough.

It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or obtain undoubtedly according to the written description of file, all should think the claimed scope of this patent.

Claims (10)

1. the Chinese medicine composition of cold cough heat clearing away cold expelling, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Dioscoreae 18-25 part; Herba Menthae 6-12 part; Radix Ophiopogonis 9-15 part; Leptandra sibirica 5-12 part; Flos Lonicerae 6-12 part; Rhizoma Anemarrhenae 4-9 part; Radix Angelicae Dahuricae 5-15 part; Rhizoma Anemones Altaicae 2-6 part; Radix Glycyrrhizae Preparata 3-9 part; Rhizoma Zingiberis Recens 2-6 part; Fructus Jujubae 6-12 part; Folium Perillae 5-15 part; Radix Platycodonis 3-12 part; Radix Peucedani 9-16 part; Fructus Arctii 9-13 part; Herba Schizonepetae 6-12 part; Fructus Viticis 4-9 part; Radix Adenophorae Trachelioidis 3-6 part; Rhizoma Et Radix Notopterygii 6-15 part; Radix Saposhnikoviae 4-14 part; Fructus Xanthii 6-15 part; Fructus Forsythiae 5-14 part; Radix Isatidis 12-20 part; Radix Bupleuri 5-12 part; Radix Scutellariae 3-9 part; Herba Lythri Salicariae 5-12 part; Radix Puerariae 6-18 part.

2. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Rhizoma Dioscoreae 20-23 part; Herba Menthae 8-10 part; Radix Ophiopogonis 11-13 part; Leptandra sibirica 7-10 part; Flos Lonicerae 8-10 part; Rhizoma Anemarrhenae 5-8 part; Radix Angelicae Dahuricae 8-12 part; Rhizoma Anemones Altaicae 3-5 part; Radix Glycyrrhizae Preparata 5-7 part; Rhizoma Zingiberis Recens 3-5 part; Fructus Jujubae 8-10 part; Folium Perillae 8-12 part; Radix Platycodonis 6-9 part; Radix Peucedani 11-14 part; Fructus Arctii 10-12 part; Herba Schizonepetae 8-10 part; Fructus Viticis 5-8 part; Radix Adenophorae Trachelioidis 4-5 part; Rhizoma Et Radix Notopterygii 9-12 part; Radix Saposhnikoviae 7-11 part; Fructus Xanthii 9-12 part; Fructus Forsythiae 8-11 part; Radix Isatidis 15-17 part; Radix Bupleuri 7-10 part; Radix Scutellariae 5-7 part; Herba Lythri Salicariae 7-10 part; Radix Puerariae 9-15 part.

3. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 22 parts of Rhizoma Dioscoreaes; 9 parts of Herba Menthaes; 12 parts of Radix Ophiopogonis; 8 parts of Leptandra sibiricas; 9 parts of Flos Loniceraes; 6 parts of the Rhizoma Anemarrhenaes; 10 parts of the Radixs Angelicae Dahuricae; 4 parts of Rhizoma Anemones Altaicaes; 6 parts of Radix Glycyrrhizae Preparatas; 4 parts, Rhizoma Zingiberis Recens; 9 parts, Fructus Jujubae; 10 parts of Folium Perillaes; 8 parts of Radix Platycodoniss; 12 parts of Radix Peucedanis; 11 parts of Fructus Arctiis; 9 parts of Herba Schizonepetaes; 6 parts of Fructus Viticises; 4.5 parts of Radix Adenophorae Trachelioidis; 11 parts of Rhizoma Et Radix Notopterygiis; 9 parts of Radix Saposhnikoviaes; 11 parts of Fructus Xanthii; 10 parts of Fructus Forsythiaes; 16 parts of Radix Isatidis; 8 parts of Radix Bupleuri; 6 parts of Radix Scutellariaes; 8 parts of Herba Lythri Salicariae; 12 parts of Radix Puerariaes.

4. according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, this Chinese medicine composition is made to pharmaceutically acceptable powder, decoction, unguentum and pill.

5. Chinese medicine composition according to claim 4, is characterized in that, the preparation method of described powder, and step is as follows:

(1) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(2) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, together with step (1) gains, be ground into altogether fine powder, cross 140-180 mesh sieve (preferably 150-170 mesh sieve, is more preferably 160 mesh sieves);

(3) Herba Menthae, Radix Ophiopogonis, Leptandra sibirica, Flos Lonicerae, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Radix Glycyrrhizae Preparata, Rhizoma Zingiberis Recens, Folium Perillae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Fructus Forsythiae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae, Herba Lythri Salicariae and Radix Puerariae are Tumblied Dry, being placed in pulverizer pulverizes, cross 160-200 mesh sieve (preferably 170-190 mesh sieve, is more preferably 180 mesh sieves);

(4) by the fine powder mixing and stirring of step (2)-(3) gained, the powder that gets product, carries out sterile packaged by the specification pharmaceutically accepted.

6. Chinese medicine composition according to claim 4, is characterized in that, the preparation method of described decoction, and step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) step (5) gained filtrate is added to ethanol, ethanol consumption is 0.5-1.5 times (preferably 0.75-1.25 times of filtrate weight, be more preferably 1 times), standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filters, filtrate recycling ethanol alcohol are also concentrated into 3/4-1/2 (the preferred 2/3-7/12 of original volume, be more preferably 5/8), sterile packaged, obtains decoction.

7. Chinese medicine composition according to claim 4, is characterized in that, the preparation method of described unguentum, and step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate to standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filter, filtrate recycling ethanol is also condensed into the thick paste that relative density is 1.2-1.4 (preferably 1.25-1.35, is more preferably 1.3) at 45 ℃, obtains unguentum.

8. Chinese medicine composition according to claim 4, is characterized in that, the preparation method of described pill, and step is as follows:

(1) Herba Menthae and Flos Lonicerae are broken into coarse powder, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), then with suitable quantity of water immersion, (the consumption standard of preferred water was for soaking medicated powder 1-2cm, be more preferably 1.5cm), be placed in distillator, pass into vapor distillation, volatile oil and water are together distilled, collect distillate, after distillate is cooling, divides and get oil reservoir, oil reservoir is heated to 100 ℃, sterilization 4-8min(preferred 5-7min, is more preferably 6min), pack air-tight bottle into after cooling standby;

(2) Fructus Xanthii is placed in preheated container, fries to surperficial buff and thorn burntly with moderate heat, inner taking-up when light yellow dried in the air coolly, grinds deburring;

(3) Fructus Jujubae and Rhizoma Dioscoreae are placed in to marmite, fry to 5 sixty percent ripe, will be ground into altogether fine powder with step (2) gains, cross 40-80 mesh sieve (preferably 50-70 mesh sieve, is more preferably 60 mesh sieves), gained medicated powder is stand-by with cotton parcel;

(4) Radix Ophiopogonis, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Rhizoma Anemones Altaicae, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, Radix Adenophorae Trachelioidis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Isatidis, Radix Bupleuri, Radix Scutellariae and Radix Puerariae are placed in to glass container, soak 1-3 days (preferred 1.5-2.5 days, be more preferably 2 days), be placed in marmite, add water, moderate heat decocts 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes);

(5) Leptandra sibirica, Radix Glycyrrhizae Preparata, Folium Perillae, Fructus Arctii, Herba Schizonepetae, Fructus Viticis, Fructus Forsythiae, Herba Lythri Salicariae and step (3) gains are placed in to the marmite of step (4), add water, decoct twice, boil 30-50 minute (preferred 35-45 minute at every turn, be more preferably 40 minutes), twice filtrate merges, and splashes into the volatile oil of step (1) gained;

(6) ethanol is added in step (5) gained filtrate, standing 3-7 hour (preferably 4-6 hour, is more preferably 5 hours), filters, filtrate recycling ethanol is also condensed into the thick paste that relative density is 1.2-1.4 (preferred 1.25-1.35 at 45 ℃, be more preferably 1.3), be modulated into loose soft material of light pressure, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;

(7) Mel is placed in pot, with slow fire, tempers, wait Mel to endure to thick, then mix the medicated powder of step (6) gained, fully mix into ointment thoroughly, by traditional Chinese medical science tradition pill method, make pill, obtain pill.

9. according to the preparation method of claim 7 and Chinese medicine composition unguentum claimed in claim 8 and pill, it is characterized in that: step (6) ethanol consumption is 0.5-1.5 times (preferably 0.75-1.25 doubly, is more preferably 1 times) of filtrate quality.

10. the preparation method of Chinese medicine composition pill according to claim 8, it is characterized in that: step (7) is joined 0.4-0.6 kilogram of Mel (preferably per kilogram medicated powder is joined 0.45-0.55 kilogram of Mel, is more preferably per kilogram medicated powder and joins 0.5 kilogram of Mel) by per kilogram medicated powder.