CN104173344A - Novel therapy for treating piles by means of painless injection - Google Patents
Novel therapy for treating piles by means of painless injection Download PDFInfo
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- CN104173344A CN104173344A CN201410476245.1A CN201410476245A CN104173344A CN 104173344 A CN104173344 A CN 104173344A CN 201410476245 A CN201410476245 A CN 201410476245A CN 104173344 A CN104173344 A CN 104173344A
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- injection
- hemorrhoid
- methylene blue
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Abstract
The invention discloses a novel therapy for treating piles by means of painless injection. Injection used in the novel therapy is characterized by being prepared from the following raw materials in proportion by weight: 2ml of 2% lidocaine hydrochloride, 2ml of 0.75% bupivacaine hydrochloride, 2ml of 25% vitamin c injection, 3ml of 2.5% PNG, 0.2ml of epinephrine, 1ml of 1% methylenum coeruleum for injection, and a solution containing 0.09% of methylenum coeruleum. The injection is injected into mucosa at the raised highest point of each haemorrhoid, the haemorrhoids are injected one by one irrespective of quantity, the dose is 1-10ml for one patient each time (according to the sizes and quantity of the haemorrhoids), the curative effect of the novel therapy is superior to the curative effect of the product for treating the piles in the market at present, and the product is simple, convenient, cheap, strong in curative effect and has better effect than traditional similar products.
Description
Technical field
The present invention relates to a kind of new therapy for the treatment of painless injection hemorrhoid, belong to Western medicine field.
Technical background
Hemorrhoid are divided into internal hemorrhoid, external hemorrhoid, mixed hemorrhoid by the difference of happening part.There is a jagged visible line in the junction of anal canal skin and rectal mucosa anal canal pectinate line.Is internal hemorrhoid more than pectinate line, supporting structure, venous plexus and arteriovenous anastomosis Zhi Fasheng pathological change or the displacement of anus pad, coating rectal mucosa, because internal sphincter shrinks, anus pad is divided into three, left side, forward right side, right lateral side with Y type ditch, and therefore internal hemorrhoid is common in left side, forward right side and right lateral side; Below pectinate line, be external hemorrhoid, coating anal canal mucosa, can be divided into connective tissue external hemorrhoid, varicosis external hemorrhoid, thrombosed external hemorrhoid; What have internal hemorrhoid and external hemorrhoid concurrently is mixed hemorrhoid, is that internal hemorrhoid merges by venous plexus and corresponding external hemorrhoid, i.e. coincideing of upper and lower venous plexus, and mixed hemorrhoid is deviate from outside anus, while being plum blossom-shaped, is called annular hemorrhoid, if by sphincter incarceration, forms strangulated hemorrhoid.
Summary of the invention
Object of the present invention is just to provide a kind of new therapy of painless injection hemorrhoid.
Western medicine preparation of the present invention and preparation method thereof, it be by: following Western medicine is made, by 2% lidocaine hydrochloride, 0.75% bupivacaine hydrochloride, 25% vitamin c injection, 2.5%PNG, epinephrine, injection 1% methylene blue, be made into containing Western medicine such as methylene blue solutions and make by following scheme, medicine each component consumption of the present invention is: by 2% lidocaine hydrochloride 2ml, 0.75% bupivacaine hydrochloride 2ml, 25% vitamin c injection 2ml, 2.5%PNG3ml, epinephrine 0.2ml, injection 1% methylene blue 1ml, be made into the solution containing methylene blue 0.09%.
Detailed description of the invention
A kind of new therapy for the treatment of painless injection hemorrhoid of the present invention, it be by: following Western medicine is made, by 2% lidocaine hydrochloride, 0.75% bupivacaine hydrochloride, 25% vitamin c injection, 2.5%PNG, epinephrine, injection 1% methylene blue, be made into containing methylene blue solution, make by following scheme:
1, medicine each component consumption of the present invention is preferably:
By 2% lidocaine hydrochloride 2ml, 0.75% bupivacaine hydrochloride 2ml, 25% vitamin c injection 2ml, 2.5%PNG3ml, epinephrine 0.2ml, injection 1% methylene blue 1ml, be made into the solution containing methylene blue 0.09%.
2, the method for medication:
After injection, one, the second stage of internal hemorrhoid and hypertrophy hemorrhoid fully recover about ten days, stageⅢhemorrhoid was fully recovered about 20 days, and mixed hemorrhoid varicosis hemorrhoid were fully recovered about one month.
3. select the standard of case:
Internal hemorrhoid, external hemorrhoid, mixed hemorrhoid have the patient of above-mentioned symptom, all, as the standard of selecting case, treat.
4. diagnostic criteria:
Silent Neuritis archorrhagia is the modal symptoms of hemorrhoid, and prolapsus is the performance that hemorrhoid further increase, and many and archorrhagia exists simultaneously.Uncomplicated hemorrhoid generally there will not be obvious pain, only show as the uncomfortable or slight dull pain of anus after an action of the bowels of the falling inflation of anal orifice, and while suffering from external hemorrhoid or mixed hemorrhoid, anus mouth can produce the soft skin tag of Silent Neuritis around, one or more, substantially can not bring discomfort.When hemorrhoid continue to emerge in outside anus, due to the stimulation of secretions, anal skin there will be the even diabrosis of humidity, pruritus, pain.Internal hemorrhoid is that surface is covered by mucosa, is positioned at tooth trace top, is formed by hemorrhoid angular vein clump, is common in center, left side, right front and right back 3 places, often has blood in stool and prolapses history.External hemorrhoid is that surface is covered by skin, is positioned at tooth trace below, is formed by the outer venous plexus of hemorrhoid, common are thrombosed external hemorrhoid, connective tissue external hemorrhoid (skin tag), varicosis external hemorrhoid and inflammatory external hemorrhoid.Mixed hemorrhoid is near tooth trace, for mucocutaneous boundary tissue covers, is formed with internal hemorrhoid and external hemorrhoid two specific characters by the vein communicating that coincide each other between hemorrhoid angular vein and the outer venous plexus of hemorrhoid.
5: therapeutic scheme:
By 2% lidocaine hydrochloride 2ml, 0.75% bupivacaine hydrochloride 2ml, 25% vitamin C injection 2ml, 2.5%PNG3ml, epinephrine 0.2ml, injection 1% methylene blue 1ml, be made into the solution containing methylene blue 0.09%.Inject under the mucosa of blood stasis protuberance peak, no matter blood stasis is how many, all noted one by one, 1ml～10ml of dose one people (according to blood stasis size and how many).
6. efficacy assessment standard:
Curative effect: after injection, one, the second stage of internal hemorrhoid and hypertrophy hemorrhoid fully recover about ten days, stageⅢhemorrhoid was fully recovered about 20 days, and mixed hemorrhoid varicosis hemorrhoid were fully recovered about one month.In whole therapeutic process, patient does not have obvious pain.Contraindication: be 1. associated with the serious primary disease such as the organ such as serious cardiovascular, Liver and kidney and hemopoietic system; 2. there are epilepsy history, severe diabetes mellitus, tumor disease; 3. the patient irritated to methylene blue, lignocaine, bupivacaine, promethazine etc.The pharmacological action of hemorrhoid is cured in injection: according to relevant scholar, think by experiment: " hemorrhoid are that mucous membrane of anal canal changes a kind of characteristic symptom that produces, its reason is mainly attributed to weakening and the anxiety hyperemia of mucous membrane of anal canal of blood vessel mucosa fixation, can suppress to reflexive the tension force of anal canal, weaken sphincteral supporting function ", promethazine has stronger antiallergic, stable, hypotensive effect, and can strengthen the effect of anesthetics, after internal hemorrhoid injection sclerotherapy PNG, can directly reduce the anxiety hyperemia of anal orifice and rectal intestine mucosa, adding of benefit (cloth is many) caine may strengthen this effect, this injection injects blood stasis makes blood stasis full, may there is the mucous membrane of rectum of making tissue and produce aseptic inflammation, the infiltration of this medicine is dissolved blood stasis gradually, downright bad, come off, wound spontaneous recovery, thereby reach the object for the treatment of blood stasis.Vitamin C has the function of antiinflammatory, antiallergic and sclerosants.Be expelled to after blood stasis, stimulate the quiet arterial intima of hemorrhoid, promote its hypertrophy, occluding vascular gradually, makes it sclerosis, and the supply of occlude blood to hemorrhoid comes off the downright bad atrophy of blood stasis, and with promethazine combination among the strong ones, effect is distinguished.
The pharmacological action of long-acting analgesic: methylene blue is a kind of basic stain, and there is to stronger affinity in nervous tissue, after local injection, acts on some teleneuron, has obvious local analgesia effect, and effect can reach 1-3 week, is good long-acting analgesic medicine.Lignocaine and bupivacaine all can be blocked the pessimal stimulus conduction of focus to central nervous system, are conducive to alleviate local pain.Lignocaine is rapid-action, but action time is short; And bupivacaine onset is slow, but long action time.Two medicines are combined utilization, have complementary advantages, and bring out the best in each other.Meanwhile, this two medicine can remove again after methylene blue injection initial several hours burn sample pain reaction.Adrenergic adding, can shrink blood capillary, stop medicinal liquid to spread to whole body, reduce the side effect of medicine to human body, improve local drug level, the allergy that can prevent again other drug simultaneously.No matter external hemorrhoid below pectinate line, be traditional operation or injection, all can cause edema and pain, solves postoperative the having an intense pain of hemorrhoid, is the problem that the doctor of anorectal section makes great efforts to probe into.Some doctors divide some in crissum injection long-acting analgesic, remove the problem of postoperative severe pain.But this method, has not only increased patient's misery, also increased the probability infecting, and the method that the author adopts is maximized favourable factors and minimized unfavourable ones, thoroughly remove the problem of severe pain after hemorrhoid injection, be worthy to be popularized.
7. statistical procedures:
Select the treatment standard of cases to there being the clinical check results such as internal hemorrhoid, external hemorrhoid, mixed hemorrhoid to show according to above-mentioned 3: 860 people adopt the new therapy of the painless hemorrhoid for the treatment of that the present invention makes, wherein male 378 people, female 292 people, the oldest person 65 years old, reckling 25 years old, average 45 years old; The elder of the course of disease 10 years.Add up 2 courses for the treatment of as follows: cure 850 people, and effective 830 people, invalid 20 people, total effective rate 97.64% does not find that there is any toxic and side effects during medication, safe and reliable.
8. conclusion
100 routine clinical experiment results demonstrations, the new therapy that this kind treated painless injection hemorrhoid is the modal symptoms of hemorrhoid to Silent Neuritis archorrhagia, and prolapsus is the performances that hemorrhoid further increase, and many and archorrhagia exists simultaneously.Uncomplicated hemorrhoid generally there will not be obvious pain, only show as the uncomfortable or slight dull pain of anus after an action of the bowels of the falling inflation of anal orifice, and while suffering from external hemorrhoid or mixed hemorrhoid, anus mouth can produce the soft skin tag of Silent Neuritis around, one or more, substantially can not bring discomfort.When hemorrhoid continue to emerge in outside anus, due to the stimulation of secretions, anal skin there will be the even diabrosis of humidity, pruritus, pain.Inject this kind of Western medicine and have significant curative effect, its symptomes complice curative effect total effective rate is respectively 97.8%.Comprehensive Correlation Chinese medicinal ointment determined curative effect, easy to use, and in application process, do not find obvious adverse reaction and have no side effect.
Claims (2)
1. treat the new therapy of painless injection hemorrhoid for one kind, it is characterized in that: be to be made by following Western medicine, by 2% lidocaine hydrochloride, 0.75% bupivacaine hydrochloride, 25% vitamin c injection, 2.5%PNG, epinephrine, injection 1% methylene blue, be made into containing tens kinds of Western medicine such as methylene blue solutions.
2. a kind of new therapy for the treatment of painless injection hemorrhoid according to claim 1, it is characterized in that: be to press row weight proportion to make, by 2% lidocaine hydrochloride 2ml, 0.75% bupivacaine hydrochloride 2ml, 25% vitamin c injection 2ml, 2.5%PNG3ml epinephrine 0.2ml, injection 1% methylene blue 1ml, be made into the solution containing methylene blue 0.09%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410476245.1A CN104173344A (en) | 2014-09-18 | 2014-09-18 | Novel therapy for treating piles by means of painless injection |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410476245.1A CN104173344A (en) | 2014-09-18 | 2014-09-18 | Novel therapy for treating piles by means of painless injection |
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| CN104173344A true CN104173344A (en) | 2014-12-03 |
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| CN201410476245.1A Pending CN104173344A (en) | 2014-09-18 | 2014-09-18 | Novel therapy for treating piles by means of painless injection |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171045A (en) * | 1994-11-09 | 1998-01-21 | 怀特霍尔实验室有限公司 | Hemorrhoidal compositions and method of use |
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- 2014-09-18 CN CN201410476245.1A patent/CN104173344A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171045A (en) * | 1994-11-09 | 1998-01-21 | 怀特霍尔实验室有限公司 | Hemorrhoidal compositions and method of use |
Non-Patent Citations (7)
| Title |
|---|
| 乔小磊: "亚甲蓝混合液局部封闭治疗混合痔外剥内扎术后疼痛的临床疗效观察", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
| 张晓刚等: "局麻药中加人肾上腺素的临床应用", 《中国医学创新》 * |
| 张晓刚等: "局麻药中加入肾上腺素的临床应用", 《中国医学创新》 * |
| 李作富: "25%维生素C治疗痔核疗效显著", 《中国医院药学杂志》 * |
| 李作富: "25%维生素C治疗痔核疗效显著", 《江西医药》 * |
| 雷宝余: "非普注射液治疗内痔、静脉曲张性混合痔62例", 《辽宁中医杂志》 * |
| 黄大庞: "《药食同源治百病①》", 31 October 2012 * |
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Application publication date: 20141203 |