CN1116046C - Injection for curing primary varix of lower limb - Google Patents

Abstract

The present invention relates to an injection used for treating primary varicose vein of lower limbs, which is composed of the components with the proportion by weight: 15 portions of medical sodium chloride and 0.5 portion of lidocaine. The composition is reasonable and novel. The results of 500 examples of clinical tests prove that the present invention has the advantages of obvious and exact treatment effect, one time cure rate which is as high as 91.2%, no toxic or side effect, no complications, low expense, etc.

Description

The injection of treatment primary varicosis of lower extremities

The present invention relates to a kind of injection that primary varicosis of lower extremities is used for the treatment of.

Primary varicosis of lower extremities is a kind of commonly encountered diseases frequently-occurring disease, according to relevant bibliographical information, south Weir sickness rate is 53%, Spain, France and New Zealand respectively are 40%, and Canada and Israel respectively are 20%, and the U.S. has 2,400 ten thousand patients approximately, and its cause of disease mainly is owing to venous valvular incompetence or stands prudent for a long time, make the intravenous increased pressure, or cold water stimulating causes.When the patient stood, the vein of lower limb expansion formed vein group tortuous, that wriggle, makes the pars affecta skin protuberance, and the shank position is more serious than thigh position; Crouch or after lower limb raised, the vein of varicose just disappeared when the patient is flat.The ill initial stage, to suffer from limb and often expand and the mild pain sense with acid, the later stage, atrophoderma appearred in regular meeting, pigmentation, symptoms such as scleroma and stasis dermatitis, chronic ulcer appear in skin, subcutaneous tissue.

At present, be used for the treatment of oral medicine being arranged and suffering from limb intravenous injection medicine of above-mentioned disease.Sodium morrhuate is domestic a kind of injection drug commonly used, the bad grasp of this pharmaceutical quantities, and weak curative effect, side effect is big, and through clinical practice (30 example), none routine one-time cure is injected at most 7 times as a result, also not complete obiteration, injection volume is big.Serious to vascular stimulation, injection back pain increases the weight of, and lasts up to for 2 weeks, occurs with allergic symptom individually.One patient Ms Zhang is wherein arranged, 38 years old, left lower extremity constitutional great saphenous varicose vein, use the 5ml sodium morrhuate and do to suffer from the shot of limb cirso-, the shank serious swelling can not be walked with descending and be reached half surplus month as a result, and the swelling that just disappears was treated in swelling half surplus year through 8 months.

The objective of the invention is to solve problems of the prior art, and provide a kind of dosage little, no complication, the one-time cure rate height has no side effect, the injection of the primary varicosis of lower extremities treatment usefulness that relapse rate is low.

Technical scheme of the present invention is based on understanding and Therapeutic Principle to primary varicosis of lower extremities mechanism, and it is main being beneficial to suffer from limb cirso-sclerosis of blood vessels, is the auxilliary medicament composing prescription that carries out with local anesthesia.

A kind of injection for the treatment of primary varicosis of lower extremities is characterized in that being made of sodium chloride medical sodium chloride and lignocaine: lignocaine=15: 0.5 (weight).

The injection of treatment primary varicosis of lower extremities provided by the invention shows through clinical effectiveness, has one-time cure rate up to 91.2%, in 12 months relapse rate low, have no side effect, no complication occurs, the prescription novelty, evident in efficacy definite, advantage such as expense is low.

The application of the injection that treatment primary varicosis of lower extremities provided by the invention is used:

Make the patient stand the vein of its varicose is fully swelled, hitch huckle with tourniquet, allow the patient sit down then or flat crouching, thrust the hypomere of the cirso-of protuberance with scalp acupuncture, use immobilization with adhesive tape, lift the trouble limb, unclamp tourniquet, the blood in the emptying cirso-, be tourniquet in the cirso-epimere again, lift lower limb and become 45 degree to push away medicine, twine Elastic bandage to proximal part, twine upper end always to cirso-by far-end.Its dosage is decided by state of an illness weight, is generally 5～15ml.

As mentioned above with the injection of treatment primary varicosis of lower extremities of the present invention, inject the cirso-of emptying, use the Elastic bandage pressure dressing, make medicinal liquid stimulate blood vessel wall to form aseptic chemistry inflammation, the blood vessel wall adhesion, remained blood forms thrombosis, whole cirso-vascular fibrosis after the machineization, inaccessible become dead space, make the blood can't adverse current and disappear.As seen 30 days above-mentioned Elastic bandages of disassemble are suffered from the limb cirso-and are disappeared.The atrophoderma that the ill later stage occurs, pigmentation, symptoms such as skin, hypodermic scleroma and stasis dermatitis fade away.

The present invention is through the clinical observation of 500 routine systems, and select medical history, the state of an illness, year make, sex and 30 suitable examples of former Therapeutic Method (sodium morrhuate) are matched group, wherein male 210 examples, women 290 examples, 20～78 years old age, the course of disease 1～36 year.Cure the disease as stated above.

Consumption: 5～15ml/ time, be generally 5ml/ time, heavily trouble can suitably increase consumption.Its clinical test results such as table 1.

Table 1 injection injection cirso-of the present invention is cured situation

	Case load	Once cure (example)	Secondary is cured (example)	Cure (example) three times	Cure (example) 4～7 times	Recurrence (example) in 12 months	Remarks
								Test group	500	456	28	16	0	7
Matched group	30	0	11	14	5	20

Test statistics shows: with injection of the present invention the patient of 500 routine primary varicosis of lower extremities is done therapeutic test, obtain significant curative effect, once cure and account for 91.2%, the secondary healing accounts for 5.6%, three healing and accounts for 3.2%, cures to recur in back 12 months to account for 1.4%, having no side effect, do not have complication occurs, the prescription novelty, determined curative effect, expense is low.

Points for attention:

Injection provided by the invention is to suffering from serious hypertension, heart disease, glomerulonephritis, the nephrotic syndrome, deep vein thrombosis of lower extremity, the seriously infull person's forbidding of dark vein valve function.

Embodiment 1

Get medical sodium chloride (Sodiam Chlotide) 150g, lignocaine (Lidocaine) hydrochlorate 5g places beaker, add a small amount of water for injection, after fully stirring makes it to dissolve fully, use filtering with microporous membrane, add the injection water to 1000ml from filter membrane, stir, be sub-packed in the 10ml peace bottle, in 100 ℃ of sterilizations 30 minutes, cool off stand-by.

Claims (1)

1, a kind of injection for the treatment of primary varicosis of lower extremities is characterized in that being mixed with by 15: 0.5 weight ratios with medical sodium chloride, lignocaine, and its quality concentration expressed in percentage by volume sodium chloride is 15%, and lignocaine is 0.5%.