CN104173311B - Process for coating traditional Chinese medicine pills for treating diabetes - Google Patents

Process for coating traditional Chinese medicine pills for treating diabetes Download PDF

Info

Publication number
CN104173311B
CN104173311B CN201410388464.4A CN201410388464A CN104173311B CN 104173311 B CN104173311 B CN 104173311B CN 201410388464 A CN201410388464 A CN 201410388464A CN 104173311 B CN104173311 B CN 104173311B
Authority
CN
China
Prior art keywords
coating
pill
coating pan
plain ball
charcoal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410388464.4A
Other languages
Chinese (zh)
Other versions
CN104173311A (en
Inventor
陈慧泼
杨德庆
张宁
宋敏
彭岚
熊开鹏
蒋丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHENGDU JIUZHITANG JINDING PHARMACEUTICAL Co Ltd
Original Assignee
CHENGDU JIUZHITANG JINDING PHARMACEUTICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHENGDU JIUZHITANG JINDING PHARMACEUTICAL Co Ltd filed Critical CHENGDU JIUZHITANG JINDING PHARMACEUTICAL Co Ltd
Priority to CN201410388464.4A priority Critical patent/CN104173311B/en
Publication of CN104173311A publication Critical patent/CN104173311A/en
Application granted granted Critical
Publication of CN104173311B publication Critical patent/CN104173311B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a process for coating traditional Chinese medicine pills for treating diabetes. The method sequentially comprises the following steps: adding uncoated pills into an obliquely arranged sugar-coating pot; starting the sugar-coating pot, and adding ethanol solution into the sugar-coating pot to wet the surfaces of the uncoated pills; adding talcum powder which accounts for 0.5-1.5 percent of the total weight of the uncoated pills into the sugar-coating pot; adding medicinal carbon which accounts for 0.5-1.2 percent of the total weight of the uncoated pills into the sugar-coating pot; adding the ethanol solution into the sugar-coating pot again for wetting the medicinal carbon layer and the talcum powder layer coating the surfaces of the uncoated pills; adding medicinal carbon which accounts for 0.1-0.2 percent of the total weight of the uncoated pills into the sugar-coating pot, and continuously rotating the sugar-coating pot for 2-4 hours for polishing so as to obtain coated pills; and drying the prepared coated pills. The process is wholly simple, easy to implement and low in cost, the coating does not have any toxic or side effect, the coated pills are round, uniform and bright in color, weight increment of the coated pills is slight, and the dose of pills taken by patients can be reduced.

Description

A kind of medicine pill art for coating treating diabetes
Technical field
The present invention relates to medicine pill preparation technology, specifically a kind of medicine pill art for coating treating diabetes.
Background technology
In the therapeutic process of diabetes, because Chinese medicine composition blood sugar reducing function steadily and Small side effects and favored.For Be easy to take and quantify to produce, typically by the Chinese medicine composition for the treatment of diabetes sequentially pass through dispensing, extractions, concentration, receipts cream, Be dried, dry cream is pulverized, always mix, soft material processed, refining medicine, pill, even up, plain ball is dried, sieve ball, coating polishing, coated pill are dry and It is prepared into pill after selecting ball.Typically by the way of sugar coating and film coating, wherein, bag is thin to during plain ball coating for prior art Film clothing has high demands to the hardness of plain ball, friability and surface smoothness, and coating process condition requires harsh, coating material price Height, and sugar coating is big to adjuvant demand, the pill after coating can increase weight more, increases the dose of patient, and high cost, Tedious process, the use of syrup is also unfavorable for that diabeticss are taken.
Content of the invention
It is an object of the invention to overcoming the deficiencies in the prior art, there is provided a kind of medicine pill coating treating diabetes Technique, its operation is simple, it is easy to accomplish, low cost, after coating pill rounding uniformly, weightening less, gloss and color and luster good, can increase The compliance of patient.
The present invention solves the above problems and is achieved through the following technical solutions: a kind of medicine pill bag treating diabetes Clothing technique, comprises the following steps:
In step one, the coating pan that the addition of plain ball is obliquely installed;
Step 2, startup coating pan, and add the ethanol solution profit of concentration of volume percent 10%~60% into coating pan Wet softening element ball surface;
Step 3, after plain ball moistened surface softens, add in it plain ball gross weight 0.5%~1.5% into coating pan Pulvis Talci;
Step 4, after Pulvis Talci after plain ball surface distributed is uniform, add in it plain ball gross weight 0.5% into coating pan ~1.2% medicinal charcoal;
Step 5, fully stick to behind pill surface after medicinal charcoal, add concentration of volume percent again into coating pan 10%~60% ethanol solution moistening is coated on medicinal layer of charcoal and the Talcum bisque on plain ball surface;
After step 6, the medicinal layer of charcoal after plain ball surface and Talcum bisque moistening, then add plain ball in it into coating pan The medicinal charcoal of gross weight 0.1%~0.2%, then keeps coating pan to obtain coated pill after being rotated further polishing 2~4h;
Step 7, by be obtained coated pill be dried.Wherein, medicinal charcoal adopts the plant of the pure natural such as coconut husk, shell, timber Activation furnace gets through pyrolysis, is coated as main coating material with it, safe without toxic side effect, will not give Patient increases burden and is used, and because using the use that completely avoid syrup during its coating, so particularly suitable In diabeticss.
In the present invention, Pulvis Talci mainly has two effects, and an effect is anti-stick, and another effect is filling pill surface, Make pill smooth surface smooth, reduce pill in follow-up frictional force when rolling bag charcoal clothing, improve mobility of particle.The present invention Through twice plus ethanol solution operation and twice plus medicinal charcoal operation during application, wherein, add ethanol solution for the first time and there are two Effect, one is to reduce the too strong viscosity of pill, prevents adhesion between pill, two is to adhere on plain ball for the ease of Pulvis Talci;The Secondary addition ethanol solution be in order that in coating pan pill during rolling friction, Talcum bisque and medicinal layer of charcoal can be more The adhesion of medicinal charcoal when closely adhering to, and being easy to add medicinal charcoal again.The present invention is for the first time plus medicinal charcoal is in order in Talcum Charcoal clothing is formed on bisque, adds the pill after medicinal charcoal can make coating for second more smooth.The present invention limits talcous use Measure 0.5%~1.5% for ball gross weight plain in coating pan, after adding Pulvis Talci, adhesion between pill, and can be all in coating pan Even smoothly roll.The present invention limit for the first time plus during medicinal charcoal medicinal charcoal consumption as coating pan in element ball gross weight 0.5%~ 1.2%, it forms one layer of uniform charcoal clothing after can guarantee that interpolation medicinal charcoal on the Talcum layer of pill.
The gradient of coating pan influences whether the upset of pill, and gradient is too small or excessive, and pill all cannot overturn, and does not have Have through effectively overturning, the pill after coating just can not reach smooth effect, and the folder of coating pan and horizontal plane Also result in pill when angle is larger and spill coating pan.In order to ensure that in coating pan, pill can normally overturn and prevent pill from splashing, Further, described coating pan and the angle of horizontal plane are 35 °~45 °.
If the rotating speed of coating pan is too low, the movement velocity of pill is low, frictional force and impact force that in coating pan, pill is subject to All less, the charcoal clothing layer of bag pill out not only not consolidation, and pill can also cannot be carried out effectively rolling, pill each Angle does not have uniform stressed and adhesion adjuvant, and leads to rough whole, has no gloss, color and luster, or even also piebaldism;If sugar-coat Pot rotating speed excessive, the frictional force that in coating pan, pill is subject to is all larger with impact force, pill as eccentricity excessive and with The rotation of coating pan rotates together, is not also effectively rolled, and bag pill out does not equally reach the effect of smooth rounding Really.In order to ensure that in coating pan, pill effectively rolls, further, the rotating speed of described coating pan is 20~46r/min.
Although Pulvis Talci has no toxic side effect, it is the adjuvant having no therapeutical effect, in order to control making of cost and patient Consumption, further, the talcous weight adding in described step 3 is 0.7% of plain ball gross weight in coating pan.
Although medicinal charcoal also has no toxic side effect, it is also the adjuvant having no therapeutical effect, in order to control cost and patient Usage amount, further, the weight adding medicinal charcoal in described step 4 is 0.75% of plain ball gross weight in coating pan.
Further, the weight adding medicinal charcoal in described step 6 is 0.15% of plain ball gross weight in coating pan.
Further, in described step 7, coated pill drying is carried out in microwave vacuum dryer, and wherein, microwave vacuum is done The design temperature of dry machine is 65~80 DEG C, and vacuum is all higher than -0.07mpa, is dried and is less than 9% to coated pill water content.Existing The drying commonly used heated-air circulation oven drying air fan circulation air supply mode of pill, i.e. wind regime when technology prepares coated pill By circulation air supply motor drive, via heater heating, the hot blast sent via air channel to drying baker interior room, then will use after Air sucks air channel becomes wind regime recirculation, and heating uses, so repeatedly.The shortcoming of this drying means is: heat is from pill Outside gradually internally conduct heat to reach dry purpose, slow drying speed, pill internal/external heating is uneven, is easily caused drying Pill splits ball, the outward appearance of impact pill afterwards, and needs operator periodically to turn over medicine, high labor intensive, and quality index is unstable.This Bright dry run adopts microwave vacuum dryer, and drying process, product quality are more controllable, have that uniform drying is quick, sterilization, The advantages of efficient energy-saving.
Further, the concentration of volume percent of the ethanol solution adding in described step 2 and step 5 is 20%, institute The weight stating the ethanol solution adding in step 2 is 3% of plain ball gross weight in coating pan, the ethanol adding in described step 5 The weight of solution is 1.75% of plain ball gross weight in coating pan.The present invention limit in step 2 add concentration of volume percent as The consumption of 20% ethanol solution is 3% of plain ball gross weight in coating pan, is avoided that plain ball fails enough moistenings and softens and lead The medicinal charcoal that adds in Pulvis Talci that cause can not add in the uniform adhesion step 3 of pill surface and step 4 is it is ensured that bag charcoal clothing The uniformity, and be avoided that plain ball to overbate and the phenomenon such as viscous ball or even pill deformation occur;The present invention limits in step 5 The consumption adding the ethanol solution that concentration of volume percent is 20% is 1.75% of plain ball gross weight in coating pan, and it is used for moistening Talcum bisque and medicinal layer of charcoal, for adding medicinal charcoal to provide condition in step 6, and are avoided that Talcum bisque and medicinal layer of charcoal mistake Degree softens and the phenomenon such as viscous ball or even pill deformation occurs.
In sum, the method have the advantages that (1) prior art carrys out moistening ball frequently with water often in coating Medicine, but because treat diabetes the universal viscosity of medicine pill stronger, meet water after viscosity increase, if add water moistening when add water very little not Soften pill surface enough to moistening, if the too many water that adds water can immerse inside pill, the tactile water layer viscosity of pill can increase, and therefore can Need substantial amounts of dried powder to fill and anti-stick, otherwise coatings will be led to coarse because of inter-adhesive between pill and not Smooth, and the utilization of a large amount of dried powder, also can affect the disintegrate of pill, for this problem, the present invention takes and uses volume basis Carry out moistening pill than the ethanol solution for 10% ~ 60%, ethanol solution viscosity itself is less, can solve and meet asking of water viscosity increase Topic, also greatly reduces the consumption of each adjuvant.Moistening pill is carried out according to water, the used in amounts of water is more than during present invention application 8%, Pulvis Talci need to be more than 2%, and the used in amounts of medicinal charcoal is more than 1.5%, and adopts concentration of volume percent 10%~60% ethanol solution Carry out moistening pill, talcous consumption can lower 65%, and the consumption of medicinal charcoal can reduce by 40%, and the consumption of ethanol solution can only account for The 59% of water consumption.
(2) after being dried for traditional art for coating coating, coatings peeling easy to crack, or even there is splitting the problem of ball, this Number of times and each consumption that invention is added by strict control wetting agent (ethanol solution of the 10% ~ 60% of indication of the present invention), To control the content of wetting agent in coated pill, it is to avoid when being dried because of the evaporation of wetting agent, pill significantly shrinks and occur Charcoal clothing layer cracking even splits the phenomenon of ball it is ensured that the smooth degree of coated pill, also greatly shortens coated pill simultaneously Drying time, that is, save the energy and also shortened the production cycle.
(3) present invention is directed to the micro-judgment that traditional art for coating is based entirely on technical staff, arbitrarily adds supplementary product consumption, Lead to supplementary product consumption big, and the big problem of coating quality difference between different batches, will be each auxiliary on the premise of ensureing coating effect The consumption of material controls in minimum zone, and not only coating effect is good, and pill weightening is few, and whole coating during present invention application The selection of process adjuvant and usage and dosage only need to reference to fixed technological process carry out just can, solve coating process pair simultaneously The requirement of operator's experience and degree of dependence, it is to avoid the uneven problem of different batches coating quality, make whole coating mistake Journey more mechanization, automatization.
(4) present invention entirety operation is simple, and simple operation is time saving and energy saving, and the present invention adopts medicinal charcoal as coating material, And adding Pulvis Talci and ethanol solution as adjuvant, three kinds of materials all have no toxic side effect, and then make the coating of present invention preparation Safe without toxic side effect, no sugar add, and suitable diabeticss are taken, and because medicinal charcoal, Pulvis Talci and ethanol solution are all low Honest and clean it is easy to get so that the coating low cost of the present invention.
(5) enrobing processes of the present invention are carried out in coating pan, and in coating process, coating pan remains that rotation makes pill enter Row rolling friction, after adding medicinal charcoal second, pill is rotated further polishing 2~4h in coating pan, by pill between continue Frictional impact power, make after coating pill rounding uniformly, uniform color, gloss polished bright, increase the compliance of patient.
(6) present invention is carried out to consumption while reaching corresponding effect in guarantee Pulvis Talci, medicinal charcoal and ethanol solution Strict restriction, increases weight after pill coating few, can reduce the dose of patient.
Specific embodiment
With reference to embodiment, the present invention is done with detailed description further, but embodiments of the present invention are not limited to This.
Embodiment 1:
A kind of medicine pill art for coating treating diabetes, the following steps including carrying out successively: add into coating pan Enter plain ball, plain ball moistened surface softens, plain ball Surface coating Talcum bisque, Pulvis Talci layer surface coat medicinal layer of charcoal, moistening element The Talcum bisque on ball surface and medicinal layer of charcoal, add medicinal charcoal and coated pill and coated pill are obtained are dried.Wherein, to sugar-coat Plain ball is added to specifically include following steps in pot: the plain ball that particle diameter is 6.0~6.8mm to be cooled to room temperature, weighs, be subsequently adding In the coating pan being obliquely installed that horizontal plane constitutes 35 ° of angles.Plain ball moistened surface softening specifically includes following steps: starts Coating pan makes it with the rotational speed of 46r/min, adds the ethanol solution of concentration of volume percent 20% into coating pan, wherein, The consumption of ethanol solution is 3% of plain ball gross weight in coating pan, and with the rotation of coating pan, the abundant moistening of ethanol solution softens Plain ball surface.Plain ball Surface coating Talcum bisque specifically includes following steps: after plain ball moistened surface softens, into coating pan Add the Pulvis Talci of plain ball gross weight 1.5% in it, with the rotation of coating pan, Pulvis Talci sticks to plain ball surface.Talcum bisque The medicinal layer of charcoal of Surface coating specifically includes following steps: after Pulvis Talci after plain ball surface distributed is uniform, adds into coating pan The medicinal charcoal of plain ball gross weight 1.2% in it, in coating pan, pill constantly rolls in it and phase mutual friction is hit tightly, medicinal charcoal Adhere to Pulvis Talci layer surface.
The Talcum bisque on moistening element ball surface and medicinal layer of charcoal specifically include following operating procedure: treat that medicinal charcoal fully adheres to After the Pulvis Talci layer surface of pill, add the ethanol solution moistening cladding of concentration of volume percent 20% again into coating pan In medicinal layer of charcoal and the Talcum bisque on plain ball surface, wherein, the consumption of ethanol solution is plain ball gross weight in coating pan 1.75%.Add medicinal charcoal and prepared coated pill specifically includes following steps: treat medicinal layer of charcoal and the Talcum bisque profit on plain ball surface After wet, then add in it medicinal charcoal of plain ball gross weight 0.2% into coating pan, be rotated further coating pan polishing 4 hours, make ball Medicine constantly rolls in coating pan, and phase mutual friction is hit tightly.Coated pill drying specifically includes following steps: coated pill is placed in microwave It is dried in vacuum drier and obtains medicinal finished product, wherein, the design temperature of microwave vacuum dryer is 80 DEG C, and vacuum is equal It is more than -0.07mpa, be dried and be less than 9% to coated pill water content.
The coated pill being obtained using the present embodiment, rounding is uniform, and bright has no toxic side effect, and pill weightening is few.
Embodiment 2:
A kind of medicine pill art for coating treating diabetes, the following steps including carrying out successively: add into coating pan Enter plain ball, plain ball moistened surface softens, plain ball Surface coating Talcum bisque, Pulvis Talci layer surface coat medicinal layer of charcoal, moistening element The Talcum bisque on ball surface and medicinal layer of charcoal, add medicinal charcoal and coated pill and coated pill are obtained are dried.Wherein, to sugar-coat Plain ball is added to specifically include following steps in pot: the plain ball that particle diameter is 6.0~6.8mm to be cooled to room temperature, weighs, be subsequently adding In the coating pan being obliquely installed of horizontal plane structure angle at 45 °.Plain ball moistened surface softening specifically includes following steps: starts Coating pan makes it with the rotational speed of 33r/min, adds the ethanol solution of concentration of volume percent 10% into coating pan, wherein, The consumption of ethanol solution is 3% of plain ball gross weight in coating pan, and with the rotation of coating pan, the abundant moistening of ethanol solution softens Plain ball surface.Plain ball Surface coating Talcum bisque specifically includes following steps: after plain ball moistened surface softens, into coating pan Add the Pulvis Talci of plain ball gross weight 1.0% in it, with the rotation of coating pan, Pulvis Talci sticks to plain ball surface.Talcum bisque The medicinal layer of charcoal of Surface coating specifically includes following steps: after Pulvis Talci after plain ball surface distributed is uniform, adds into coating pan The medicinal charcoal of plain ball gross weight 0.75% in it, in coating pan, pill constantly rolls in it and phase mutual friction is hit tightly, medicinal charcoal Adhere to Pulvis Talci layer surface.
The Talcum bisque on moistening element ball surface and medicinal layer of charcoal specifically include following operating procedure: treat that medicinal charcoal fully adheres to After the Pulvis Talci layer surface of pill, add the ethanol solution moistening cladding of concentration of volume percent 10% again into coating pan In medicinal layer of charcoal and the Talcum bisque on plain ball surface, wherein, the consumption of ethanol solution is plain ball gross weight in coating pan 1.75%.Add medicinal charcoal and prepared coated pill specifically includes following steps: treat medicinal layer of charcoal and the Talcum bisque profit on plain ball surface After wet, then add in it medicinal charcoal of plain ball gross weight 0.15% into coating pan, be rotated further coating pan polishing 2 hours, make ball Medicine constantly rolls in coating pan, and phase mutual friction is hit tightly.Coated pill drying specifically includes following steps: coated pill is placed in microwave It is dried in vacuum drier and obtains medicinal finished product, wherein, the design temperature of microwave vacuum dryer is 50 DEG C, vacuum It is all higher than -0.07mpa, be dried and be less than 9% to coated pill water content.
The coated pill being obtained using the present embodiment, rounding is uniform, and bright has no toxic side effect, and pill weightening is few.
Embodiment 3:
A kind of medicine pill art for coating treating diabetes, the following steps including carrying out successively: add into coating pan Enter plain ball, plain ball moistened surface softens, plain ball Surface coating Talcum bisque, Pulvis Talci layer surface coat medicinal layer of charcoal, moistening element The Talcum bisque on ball surface and medicinal layer of charcoal, add medicinal charcoal and coated pill and coated pill are obtained are dried.Wherein, to sugar-coat Plain ball is added to specifically include following steps in pot: the plain ball that particle diameter is 6.0~6.8mm to be cooled to room temperature, weighs, be subsequently adding In the coating pan being obliquely installed that horizontal plane constitutes 40 ° of angles.Plain ball moistened surface softening specifically includes following steps: starts Coating pan makes it with the rotational speed of 20r/min, adds the ethanol solution of concentration of volume percent 60% into coating pan, wherein, The consumption of ethanol solution is 3% of plain ball gross weight in coating pan, and with the rotation of coating pan, the abundant moistening of ethanol solution softens Plain ball surface.Plain ball Surface coating Talcum bisque specifically includes following steps: after plain ball moistened surface softens, into coating pan Add the Pulvis Talci of plain ball gross weight 0.5% in it, with the rotation of coating pan, Pulvis Talci sticks to plain ball surface.Talcum bisque The medicinal layer of charcoal of Surface coating specifically includes following steps: after Pulvis Talci after plain ball surface distributed is uniform, adds into coating pan The medicinal charcoal of plain ball gross weight 0.5% in it, in coating pan, pill constantly rolls in it and phase mutual friction is hit tightly, medicinal charcoal Adhere to Pulvis Talci layer surface.
The Talcum bisque on moistening element ball surface and medicinal layer of charcoal specifically include following operating procedure: treat that medicinal charcoal fully adheres to After the Pulvis Talci layer surface of pill, add the ethanol solution moistening cladding of concentration of volume percent 60% again into coating pan In medicinal layer of charcoal and the Talcum bisque on plain ball surface, wherein, the consumption of ethanol solution is plain ball gross weight in coating pan 1.75%.Add medicinal charcoal and prepared coated pill specifically includes following steps: treat medicinal layer of charcoal and the Talcum bisque profit on plain ball surface After wet, then add in it medicinal charcoal of plain ball gross weight 0.1% into coating pan, be rotated further coating pan polishing 3 hours, make ball Medicine constantly rolls in coating pan, and phase mutual friction is hit tightly.Coated pill drying specifically includes following steps: coated pill is placed in microwave It is dried in vacuum drier and obtains medicinal finished product, wherein, the design temperature of microwave vacuum dryer is 35 DEG C, vacuum It is all higher than -0.07mpa, be dried and be less than 9% to coated pill water content.
The coated pill being obtained using the present embodiment, rounding is uniform, and bright has no toxic side effect, and pill weightening is few.
As described above, the present invention can preferably be realized.

Claims (8)

1. a kind of medicine pill art for coating treating diabetes is it is characterised in that comprise the following steps:
In step one, the coating pan that the addition of plain ball is obliquely installed;
Step 2, startup coating pan, and the ethanol solution moistening of addition concentration of volume percent 10%~60% is soft into coating pan Change plain ball surface;
Step 3, after plain ball moistened surface softens, add in it Talcum of plain ball gross weight 0.5%~1.5% into coating pan Powder;
Step 4, after Pulvis Talci after plain ball surface distributed is uniform, add into coating pan in it plain ball gross weight 0.5%~ 1.2% medicinal charcoal;
Step 5, fully stick to behind pill surface after medicinal charcoal, add into coating pan again concentration of volume percent 10%~ 60% ethanol solution moistening is coated on medicinal layer of charcoal and the Talcum bisque on plain ball surface;
After step 6, the medicinal layer of charcoal after plain ball surface and Talcum bisque moistening, then add plain ball gross weight in it into coating pan The medicinal charcoal of amount 0.1%~0.2%, then keeps coating pan to obtain coated pill after being rotated further polishing 2~4h;
Step 7, by be obtained coated pill be dried.
2. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described sugar-coat Pot is 35 °~45 ° with the angle of horizontal plane.
3. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described sugar-coat The rotating speed of pot is 20~46r/min.
4. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described step The talcous weight adding in three is 0.7% of plain ball gross weight in coating pan.
5. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described step The weight adding medicinal charcoal in four is 0.75% of plain ball gross weight in coating pan.
6. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described step The weight adding medicinal charcoal in six is 0.15% of plain ball gross weight in coating pan.
7. a kind of medicine pill art for coating treating diabetes according to claim 1 is it is characterised in that described step In seven, coated pill drying is carried out in microwave vacuum dryer, and wherein, the design temperature of microwave vacuum dryer is 35~80 DEG C, vacuum is all higher than -0.07mpa, is dried and is less than 9% to coated pill water content.
8. a kind of medicine pill art for coating treating diabetes according to any one in claim 1~7, its feature It is, the concentration of volume percent of the ethanol solution adding in described step 2 and step 5 is 20%, add in described step 2 The weight of the ethanol solution entering is 3% of plain ball gross weight in coating pan, and the weight of the ethanol solution adding in described step 5 is The 1.75% of plain ball gross weight in coating pan.
CN201410388464.4A 2014-08-08 2014-08-08 Process for coating traditional Chinese medicine pills for treating diabetes Active CN104173311B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410388464.4A CN104173311B (en) 2014-08-08 2014-08-08 Process for coating traditional Chinese medicine pills for treating diabetes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410388464.4A CN104173311B (en) 2014-08-08 2014-08-08 Process for coating traditional Chinese medicine pills for treating diabetes

Publications (2)

Publication Number Publication Date
CN104173311A CN104173311A (en) 2014-12-03
CN104173311B true CN104173311B (en) 2017-01-25

Family

ID=51954845

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410388464.4A Active CN104173311B (en) 2014-08-08 2014-08-08 Process for coating traditional Chinese medicine pills for treating diabetes

Country Status (1)

Country Link
CN (1) CN104173311B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115054584A (en) * 2022-07-08 2022-09-16 上海和黄药业有限公司 Coating composition for traditional Chinese medicine pills

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103623211A (en) * 2013-11-29 2014-03-12 成都九芝堂金鼎药业有限公司 Preparation method of traditional Chinese medicinal pills for treating diabetes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103623211A (en) * 2013-11-29 2014-03-12 成都九芝堂金鼎药业有限公司 Preparation method of traditional Chinese medicinal pills for treating diabetes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
自制"降糖丸"的包炭衣方法;王慧敏 等;《职业与健康》;20010131;第17卷(第1期);第129-130页 *

Also Published As

Publication number Publication date
CN104173311A (en) 2014-12-03

Similar Documents

Publication Publication Date Title
CN104017693B (en) The production technique of a kind of dried orange peel fermented glutinous rice
CN102021841A (en) Manufacture method of far infrared technological shell fabric
CN104173311B (en) Process for coating traditional Chinese medicine pills for treating diabetes
CN102138970A (en) Method for preparing compound salvia tablet
CN102133251B (en) Processing method for improving ginsenosides content in radix ginseng rubra
CN102772517B (en) Preparation method of guizhi fuling capsules
CN101579449A (en) Method for preparing oleum viticis negundo dripping pills
CN102919482A (en) Peanut sesame seed candy and preparation method thereof
CN106561864A (en) Tea leaf cell disruption processing method
CN104434870B (en) A kind of enteric gelatin hollow capsule and preparation method thereof
CN103880402B (en) A kind of preparation method of high emissivity far infrared health care boccaro ceramics
CN109953970A (en) A kind of method of dragee coatings program optimization
CN201519303U (en) Chufa-type coating pan
CN201864943U (en) Gluing device of glass fiber cloth
CN105560296A (en) Wax mud for hot compress and physiotherapy
CN102885881A (en) Liver heat removing film coated tablet and preparation method thereof
CN207590014U (en) Tealeaves vial-type roasting machine
CN104606477A (en) Fire-clearing jasmine and radix ophiopogonis film-coated tablets and preparation method thereof
CN105919964A (en) Coating method of black coating solid preparation
CN109832323A (en) A kind of preparation method of low grease content fried dough twist
CN212347186U (en) Coating equipment
CN203408258U (en) Medicinal sugar coating machine
CN206150381U (en) Nine layers of boiling device for cake
CN205718406U (en) A kind of comprehensive stoving rack of capsule
CN111821188A (en) Coating equipment and method and preparation method of heart disease treating pills

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant