CN104161871B - Tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine and preparation method thereof - Google Patents
Tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of tinea capitis (tinea alba) external and rub painting medicated wine and preparation method thereof with the hands, take off the primary raw material stating weight proportion to be prepared from: Retinervus Luffae Fructus 20 parts, Radix Saposhnikoviae 10 parts, Fructus Gardeniae 17 parts, Radix Platycodonis 9 parts, 10 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 65 parts, Camphora 1.8 parts, Borneolum Syntheticum 2.1 parts, brandy 500 parts.This product is on the basis of summing up forefathers' experience, with reference to modern pharmacological research, can effectively improve skin of head microcirculating state, impel telangiectasis, blood circulation promoting, activate hair follicle vigor, strengthen that scalp is multiple slimly exchanges penetrating power with hair follicle, thus make hair follicle restore funcitons again, absorb required nutrient, reach the object for the treatment of tinea capitis (tinea alba).
Description
Technical field
The present invention relates to traditional Chinese medicine field.Particularly relate to and rub painting medicated wine and preparation method thereof with the hands for tinea capitis (tinea alba) external.
Background technology
Tinea capitis is equivalent to the tinea alba of doctor trained in Western medicine, is a kind of tinea mostly occurred at head, and with de-white scales, then hair fractures and comes off into the dermatophytosis infectious disease that tinea alba is feature for a long time.Clinical manifestation is the raw white scales of scalp, alopecia becomes tinea alba to be the dermatophytosis infectious disease of Clinical symptoms.Tinea alba mainly infects caused by Microsporum ferrugineum in China.Often cause popular at cities and towns nursery school or primary school.Being all almost childhood onset, is many with boy especially.Pathological changes is coated with patch that is circular or difform canescence squama from the beginning of, scalp, and little person is as bean, and large person, as money, is with the passing of time spread, and expands in flakes.Hair dries up, and easily fractures, and is easy to dial Jiang, and not pain, most from scalp 0.2-0.8cm place; Hair fractures voluntarily, and length is uneven.Medical science is taught, and educating net, to collect the hair be organized in close to scalp dry peripheral, often have canescence mycoclena around.Conscious pruritus.Site of pathological change is in the majority with the crown, occipitalia, but an edge place is not generally involved.Adolescence can spontaneous recovery, newly sends out regeneration, preventing from scar.But also there is a few patients, though symptom significantly alleviates, also may become Adult chronic Hairdresser ringworm, become the source of infection in family.Primary disease is recorded head and is seen the Sui Dynasty " General Treatise on the Cause and Symptoms of Diseases ".Have in Ming Dynasty's " Waike Zhengzong, Orthodox Manual of External Diseases " and explicitly point out its paathogenic factor and the route of infection.Later all families are all thought caused by contagion.Tinea capitis is many to be caused by mutual immediate contagion; Or because accumulateing in damp-heat in the spleen and stomach, wet Sheng is pruritus stream juice then, intenseness of heat is then given birth to dry humorously, failure of skin and muscle to be nourished, so that skin gives birth to white scales, shrivelled the coming off of hair forms.
The medicine for the treatment of tinea capitis is a lot, and as griseofulvin, daktarin, clotrimazole, Herba Senecionis Dianthui etc., but therapeutic effect is all undesirable, and costly, toxic and corrosivity, has certain damage to skin, and treatment time is long, and cure rate is low, weak effect.Life-time service easily causes body damage, immunity degradation.
For the problem of above-mentioned hair growth promoting, the Chinese patent literature of publication number CN103908575A (application number 201410162166.3) discloses one and treats tinea capitis, Chinese medicinal ointment of tinea alba and preparation method thereof, it is by being mainly prepared from by following raw materials in parts by weight number ratio: Radix Pulsatillae 9-15 part, Limax 20-30 part, Cortex Meliae 6-12 part, Pericarpium Citri grandis 3-9 part, Semen Ginkgo 3-9 part, Rhizoma Osmundae 3-9 part, opal 3-9 part, Cortex Phellodendri 3-9 part, Rhizoma Polygonati 9-15 part, Rhizoma et radix veratri (Radix Rhizoma Veratri) 0.2-0.6 part, Indigo Naturalis 2-6 part, Semen Lepidii (Semen Descurainiae) 3-9 part, Radix Angelicae Dahuricae 3-9 part, Nicotiana tabacum L. 9-15 part, Folium Melo 9-15 part.The Chinese patent literature of publication number CN103156815A (application number 201110415991.6) discloses a kind of dispersible tablet formulation for tinea alba disease, and it is by being mainly prepared from by following raw materials in parts by weight number ratio: liranaftate 20 parts, glycerol 100 parts, sodium carboxymethyl cellulose 28 parts, cutaneous permeable agent 20 parts, ethanol 200 parts.The Chinese patent literature of publication number 101342251A (application number 200810139076.7) discloses a kind of external used medicine for the treatment of tinea capitis.It is prepared from by following raw materials in parts by weight number ratio: Flos Carthami 12-18 part, Radix Saposhnikoviae 15-20 part, Alumen 10-18 part, sulfur 9-15 part, Rhizoma Coptidis 6-18 part, Pericarpium Zanthoxyli 12-20 part, Camphora 6-9 part, Calomelas 6-12 part, Indigo Naturalis 6-12 part, Herba Polygoni cymosi 6-9 part.The method for the treatment of tinea capitis (tinea alba) at present is both at home and abroad more, as western medicine, and herbal treatment, but therapeutic effect is all undesirable, and costly, toxic and corrosivity, have certain damage to skin, treatment time is long, and cure rate is low, weak effect.Life-time service easily causes body damage, immunity degradation.
Summary of the invention
For the deficiencies in the prior art, add oral drugs and be rich in hormone more, easily cause body metabolism disorderly, even Secondary cases fungus, viral infection, and hair transplant all can cause the deep lesions of hair follicle to a certain extent, cortex is totally disrupted, and cannot repair.An object of the present invention is that the external providing one effectively can treat tinea capitis (tinea alba) is rubbed with the hands and is coated with medicated wine, adopts medical material comparatively common in the localities as raw material, with low cost.There is therapeutic effect good, have no side effect, the advantage that treatment cost is low.The preparation method being coated with medicated wine is rubbed in the external that another object of the present invention is just to provide above-mentioned tinea capitis (tinea alba) with the hands.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, takes off the primary raw material stating weight proportion and is prepared from: Retinervus Luffae Fructus 16-25 part, Radix Saposhnikoviae 8-12 part, Fructus Gardeniae 12-22 part, Radix Platycodonis 6-12 part, Pericarpium Zanthoxyli 5-15 part, fresh Flos Celosiae Cristatae 50-80 part, Camphora 0.5-3.0 part, Borneolum Syntheticum 1.2-3.0 part, and brandy 400-600 part (preferred, brandy 450-550 part, be more preferably, brandy 500 parts).
Tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, preferred scheme is, take off the primary raw material stating weight proportion to be prepared from: Retinervus Luffae Fructus 18-22 part, Radix Saposhnikoviae 9-11 part, Fructus Gardeniae 15-19 part, Radix Platycodonis 8-10 part, Pericarpium Zanthoxyli 8-12 part, fresh Flos Celosiae Cristatae 60-70 part, Camphora 1.5-2.0 part, Borneolum Syntheticum 1.9-2.3 part, brandy 450-550 part.
Tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, and the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Retinervus Luffae Fructus 20 parts, Radix Saposhnikoviae 10 parts, Fructus Gardeniae 17 parts, Radix Platycodonis 9 parts, 10 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 65 parts, Camphora 1.8 parts, Borneolum Syntheticum 2.1 parts, brandy 500 parts.
The preparation method being coated with medicated wine is rubbed in above-mentioned tinea capitis (tinea alba) external with the hands, and step is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, and 10-25 days is soaked in sealing, and every day shakes;
(2) add proper honey to stir, continue fermentation 10-25 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
According to preparation method recited above: the concentration of step (1) brandy is 50 °-70 ° (preferred concentration is 55 °-65 °, and being more preferably concentration is 60 °).
According to preparation method recited above: shake step (1) every day (preferred every day shakes 3-6 time, is more preferably and shakes 5 every day).
According to preparation method recited above: 10-25 days (preferred 12-18 days is more preferably 15 days) is soaked in step (1) sealing.
According to preparation method recited above: step (2) adds Mel (consumption of preferred Mel is the 5%-7% of brandy quality, is more preferably 6%).
According to preparation method recited above: step (2) fermentation 10-25 days (preferred 12-18 days is more preferably 15 days).
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
The present invention compared with prior art, need not take medicine, and without hospitalization, makes simple and convenient, has no side effect.Select common Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis, Pericarpium Zanthoxyli, Flos Celosiae Cristatae and brandy, and Camphora and Borneolum Syntheticum, with low cost, compatibility is reasonable, easy to use, and have skin moistening and to invigorate blood circulation, promote effect of hair growth promoting, Be very effective, has good curative effect.
The pharmacological effect of each crude drug is respectively:
Retinervus Luffae Fructus: sweet in the mouth is flat.Return lung, stomach, Liver Channel.Main chemical compositions is xylan and cellulose, also may contain mannan, galactan and lignin etc.The particular matters such as the saponins in the middle of Fructus Luffae, luffein, lymphatic temperament, wood glue, citrulline, xylan and interferon have certain special role.Contained by prevent the vitamin B1 of skin aging, the compositions such as the vitamin C of skin whitening, can protect skin, eliminate speckle, making skin pure white, delicate, is rare cosmetic good merchantable brand, therefore Sucus Luffae has the title of " beauty's water ".Have that dysmenorrhea is active, effect of removing heat-phlegm.Control pain in chest and hypochondrium, stomachache, lumbago, lung-heat productive cough, carbuncle, anal fistula.
Radix Saposhnikoviae: acrid in the mouth, sweet, warm.Return liver, spleen, urinary bladder channel.Main chemical compositions is volatile oil, mannitol, bitterness glycoside etc.Fresh RADIX SAPOSHINOKOVIAE from Northeast press liquor is tested in vitro, has certain antibacterial action to bacillus pyocyaneus and staphylococcus aureus.Kind also has certain antibacterial action without the Radix Saposhnikoviae decoct of qualification to Hemolytic streptococcus and dysentery bacterium.Radix Saposhnikoviae also has inducing diaphoresis to dispel wind, and victory is wet, effect of relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Radix Platycodonis: nature and flavor: bitter, pungent is flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Fructus Gardeniae: bitter in the mouth, cold.GUIXIN, liver, lung, stomach warp.Main chemical compositions is for containing flavonoid gardenin, pectin, tannin, crocin, crocetin, PEARLITOL 25C, nonacosane, cupreol.The another glycoside containing the smelly formaldehyde structure of multiple tool ring: gardenoside, geniposide pool element-1-glycoside, lattice Tegosept P-1-β-D-gentiobioside and shanzhiside in a small amount.There is heat clearing away, pathogenic fire purging, effect of removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.
Pericarpium Zanthoxyli: acrid in the mouth, temperature, poisonous.Return spleen, stomach, kidney channel.Main chemical compositions Pericarpium Zanthoxyli fruit containing volatile oil 0.7%(Guizhou produce), 2 ~ 4%(Gansu produce), 4 ~ 9%(Guangdong produce).Containing Geraniol, limonene, cumic alcohol etc. in volatile oil.Fruit is still containing sterol, unsaturated organic acid etc.Contained Geraniol, low dose can suppress the spontaneous activity of rat.To isolated rabbit small intestinal, act on non-constant during low concentration.Sometimes have slightly but motion more of a specified duration is hyperfunction, heavy dose then suppresses bowel movement.Geraniol has anthelmintic action to Cavia porcellus ascarid.According to another report, the rare alcohol liquid of Pericarpium Zanthoxyli has local anesthesia effect, and in the topical anesthesia of rabbit cornea, effect is slightly weak compared with tetracaine; In the infiltration anesthesia of Cavia porcellus, effect is better than procaine.There is warming middle-JIAO to relieve pain, effect of killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.
Fresh Flos Celosiae Cristatae: sweet in the mouth, puckery, cool in nature.Return liver, large intestine channel.Main chemical compositions is containing Kaempferitrin, amaranth glycoside, pinitol and volume potassium nitrate.Containing the multivitamin such as protein, fat, folic acid, pantothenic acid, vitamin B1, B2, B4, B12, C, D, E, K, and Kaempferitrin, amaranth glycoside, pinite, pinitol, potassium nitrate, 21 seed amino acids, 13 kinds of trace element and more than 51 kinds natural and enzyme cofactor, wherein in seed, protein content, up to 73%, can supplement the deficiency of grain content.There is astringing to arrest bleeding, leukorrhagia stopping, effect of dysentery relieving.For spitting blood, metrorrhagia, has blood in stool, hemorrhoidal bleeding, leucorrhea with red and white discharge, and chronic dysentery is more than.
Camphora: main component is pure gum camphor is a kind of terpenoid organic compound.There is orifice opening, qi stagnation removing, ward off foul, killing parasites for relieving itching, reducing swelling and alleviating pain effect, cure mainly the symptoms such as scabies pruritus, traumatic pain, toothache.Oleum Camphora forms primarily of various terpenoid.The continuous rectification under vacuum of general multi-tower type, obtains Gum Camphor and various essential oil (as cineole, linalool, Oleum Pini outer coffin, safrole) and side-product (as white camphor oil, red camphor oil, blue camphor oil) in conjunction with techniques such as freezing, distillations.
Borneolum Syntheticum: this product is the fresh skill of canella Camphor tree, leaf is through extracting the crystallization of being processed into.Acrid in the mouth, hardship, cool in nature.There is refreshment of having one's ideas straightened out, effect of clearing away heat to alleviate pain.Faint for calentura kind dusk, convulsion, apoplexy syncope due to accumulation of phlegm, infantile convulsion expectorant fan, sore throat toothache, order carbuncle sore infections, conjunctival congestion.
Brandy: be the high-quality famous brand of wine that a kind of wine is brewageed through distillation, by people are liked, its alcohol content about 40% ~ 50%.Custom is being raw material with Fructus Vitis viniferae, and the wine through fermentation, distillation, storage, allotment is called brandy.Brandy beauty and skin care good merchantable brand, has special skin effect using brandy as the skin protection cosmetics of additive.With brandy bathing, the blood circulation improving skin, reach the effect of beauty and skin care.In shampoo, add a little brandy, limit side washing massaging scalp, adheres to for a long time, and hair can be made no longer to come off.
The present invention, based on pathogeny and the treatment by Chinese herbs principle of tinea capitis (tinea alba), with reference to modern pharmacological research, selects the medicine of blood circulation promoting and blood stasis dispelling, removing toxic substances parasite killing, can killing parasites for relieving itching, the object of dispeling the wind and reaching and treating tinea capitis (tinea alba) of detoxifying.
Technical advantage of the present invention is also embodied in:
1, tinea capitis of the present invention (tinea alba) external is rubbed with the hands and is coated with medicated wine, can effectively improve skin of head microcirculating state, impel telangiectasis, blood circulation promoting, activate hair follicle vigor, strengthen that scalp is multiple slimly exchanges penetrating power with hair follicle, thus make hair follicle restore funcitons again, absorb required nutrient, reach the object of hair restoration.
2, the present invention is directed to the alopecia caused by tinea capitis (tinea alba), reasonable disposition, can alopecia be suppressed, promote hair regeneration, cultivate and improve germinal cell activity and hair follicle environment; Character is gentle, and safety non-toxic, to skin without any stimulation.
3, selected materials is all Chinese medicine material, has no side effect; Also there is the effect of nutrition and moist hair simultaneously.
4, medicated wine of the present invention have rapid-action, Transdermal absorption power strong, with the advantage such as skin affinity is good, physical stability is good, steady quality, technique are simple.
5, medicine source is easy to get, with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, takes off and states primary raw material and be prepared from (every part of 25g): Retinervus Luffae Fructus 16 parts, Radix Saposhnikoviae 8 parts, Fructus Gardeniae 12 parts, Radix Platycodonis 6 parts, 5 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 50 parts, Camphora 0.5 part, Borneolum Syntheticum 1.2 parts, brandy 400 parts.
The preparation process that painting medicated wine is rubbed in tinea capitis (tinea alba) external with the hands is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, sealing immersion 10 days, and every day shakes;
(2) add proper honey to stir, continue fermentation 10 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
model case one:zhao XX, female, 27 years old, Anshan, liaoning Province people, scalp squama speckle, broke and sends out two weeks, conscious local pruritus.Check: right top scalp has a diameter to be about the circular skin lesion district of 4cm.Hair 0.2 ~ 0.5cm place on scalp fractures, and disconnected undesirable root of sending out is shown in there is canescence squama sheath, and hair around loosens easily to be pulled out.After auris dextra, skin has a diameter to be about the circular erythema of 1cm, and border is clear, and edge is protuberance slightly, and there is fines on surface.Get disease and add the direct microscopy of 10% potassium hydroxide solution, see and have a large amount of fungus sporidiole to be zyklopisch arrangement around root of hair.Be diagnosed as tinea alba.
Once accidental, Mrs Zhao has heard that from colleague there the external of tinea capitis of the present invention (tinea alba) is rubbed with the hands and has been coated with medicated wine, after she has carefully studied several raw material of the present invention, admits especially.So determine to make a try, after using the external of embodiment 1 gained tinea capitis (tinea alba) to rub with the hands to be coated with a course for the treatment of of medicated wine, alopecia decreases; Continue to use tinea capitis (tinea alba) external of embodiment 1 gained to rub with the hands and be coated with a course for the treatment of of medicated wine, the place of tinea alba starts to grow hair; Adhere to using tinea capitis (tinea alba) external of embodiment 1 gained to rub the time being coated with 4 courses for the treatment of of medicated wine with the hands, on head, two major parts tinea alba disappears substantially, and it is not only black but also close that hair is grown.Adhere to using tinea capitis (tinea alba) external of embodiment 1 gained to rub with the hands and be coated with 6 courses for the treatment of of medicated wine, the place of tinea alba is thoroughly long good.Till now, all pass by more than 1 year, tinea alba recurred never again.
embodiment 2tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, takes off and states primary raw material and be prepared from (every part of 10g): Retinervus Luffae Fructus 25 parts, Radix Saposhnikoviae 12 parts, Fructus Gardeniae 22 parts, Radix Platycodonis 12 parts, 15 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 80 parts, Camphora 3.0 parts, Borneolum Syntheticum 3.0 parts, brandy 600 parts.
The preparation process that painting medicated wine is rubbed in tinea capitis (tinea alba) external with the hands is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, sealing immersion 25 days, and every day shakes;
(2) add proper honey to stir, continue fermentation 25 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
model case two:open XX, 17 years old, female, student, family had cat and dog.Like playing with cat and dog.Private prosecution had a pitch-black beautiful hair originally, a period of time WA finds pillow covering towel is scattered a little hair, be not present to the mind at the beginning, afterwards, find on living room floors, toilet is the hair dropped everywhere, hair on head is more and more rare, alopecia is also very abnormal, and scalp itch, feels that Things are in a bad way.So have purchased shampoo and the hair conditioner of some anticreep anti-avulsions voluntarily, but DeGrain, and alopecia still continues.Patient uses western medicine instead again, and rub with the hands simultaneously and be coated with some ointment, kindred circumstances does not take a turn for the better.Find on inspection, the visible 7 place 10 ~ 15cm diameter circular canescence scaling patches of head, hair is fractureing apart from scalp 4--8cm place, disconnected root of hair have mycoclena around, send out, in bright green fluorescence by filtration ultraviolet lamps irradiates disease.Be diagnosed as " tinea alba ".After having understood tinea capitis of the present invention (tinea alba) external stranding painting medicated wine and its raw material prescription, she has determined to make a try.When tinea capitis (tinea alba) external of use embodiment 2 gained is rubbed with the hands and is coated with medicated wine similar 2 courses for the treatment of, skin lesion disappears, and hair growth is good, filters Burdick lamp inspection, and without bright green fluorescence, she is very happiness.Continue to use tinea capitis (tinea alba) external of embodiment 2 gained to rub the time being coated with medicated wine about 4 courses for the treatment of with the hands, dense shiny black before hair has recovered again.Recurrence of following up a case by regular visits to that so far there are no.
embodiment 3tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, takes off and states primary raw material and be prepared from (every part of 20g): Retinervus Luffae Fructus 18 parts, Radix Saposhnikoviae 9 parts, Fructus Gardeniae 15 parts, Radix Platycodonis 8 parts, 8 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 60 parts, Camphora 1.5 parts, Borneolum Syntheticum 1.9 parts, brandy 450 parts.
The preparation process that painting medicated wine is rubbed in tinea capitis (tinea alba) external with the hands is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, sealing immersion 12 days, and every day shakes;
(2) add proper honey to stir, continue fermentation 12 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
model case three:king XX, man, 50 years old, people from the middle part of Fujian Province, Sichuan.Mr. Wang has opened an auto repair shop, well can not note health owing to working at ordinary times, normal with a face streaming with sweatly tired again.Cause head infection fungus, cause tinea alba.Be that head has one piece of white macula at first, white macula expanded, spread to surrounding afterwards, and fell scurf from level to level, and lesion hair dries up, frangibility, gradually alopecia.One when having a symptom above, and Mr. Wang just goes to hospital to check, is diagnosed as tinea alba.So, start with western medicine, but DeGrain.Rear Mr. Wang is smeared with external-applied ointment again, and result is undesirable equally.Through checking the tinea alba being diagnosed as fungal infection and causing.
Just when Mr. Wang is downhearted, tinea capitis of the present invention (tinea alba) external that allowed him recognize of accidental chance is rubbed with the hands and is coated with medicated wine, have the attitude of trying in arms, Mr. Wang brings into use tinea capitis (tinea alba) external of the embodiment of the present invention 3 gained to rub painting medicated wine with the hands, less than two weeks, symptom was obviously improved, and it is black again that alopecia director makes new advances, hair hard again, scalp is not in pruritus.Continue to use tinea capitis (tinea alba) external of the embodiment of the present invention 3 gained to rub with the hands and be coated with 3 courses for the treatment of of medicated wine, white macula disappears, hair looks not only black but also close, does not a bit see the vestige of alopecia, adheres to that again using tinea capitis (tinea alba) external of the embodiment of the present invention 3 gained to rub painting medicated wine with the hands consolidates 2 courses for the treatment of.In the return visit in later stage, do not recur again.
embodiment 4tinea capitis (tinea alba) external is rubbed with the hands and is coated with medicated wine, takes off and states primary raw material and be prepared from (every part of 10g): Retinervus Luffae Fructus 22 parts, Radix Saposhnikoviae 11 parts, Fructus Gardeniae 19 parts, Radix Platycodonis 10 parts, 12 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 70 parts, Camphora 2.0 parts, Borneolum Syntheticum 2.3 parts, brandy 550 parts.
The preparation process that painting medicated wine is rubbed in tinea capitis (tinea alba) external with the hands is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, sealing immersion 18 days, and every day shakes;
(2) add proper honey to stir, continue fermentation 18 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
embodiment 5the external of tinea capitis (tinea alba) is rubbed with the hands and is coated with medicated wine, takes off to state primary raw material and be prepared from (every part of 20g): Retinervus Luffae Fructus 20 parts, Radix Saposhnikoviae 10 parts, Fructus Gardeniae 17 parts, Radix Platycodonis 9 parts, 10 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 65 parts, Camphora 1.8 parts, Borneolum Syntheticum 2.1 parts, brandy 500 parts.
The preparation process that painting medicated wine is rubbed in tinea capitis (tinea alba) external with the hands is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, sealing immersion 15 days, and every day shakes;
(2) add proper honey to stir, continue fermentation 15 days, filter and remove residue, get upper strata clarification medicated liquor;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
Using method: dip medicated wine with absorbent cotton and put it on the skin, every day 3-5 time, 10 days courses for the treatment of.
test example:in order to verify that the drug effect being coated with medicated wine is rubbed in tinea capitis (tinea alba) external of embodiment 5 gained with the hands, We conducted contrast test.Tinea alba patient 300 people is selected in experiment, and be divided into matched group and administration group randomly, every panel size is identical, is respectively 150 people.Administration group: our every days same equal time, use under square one absorbent cotton dip tinea capitis (tinea alba) external of embodiment 5 gained rub with the hands be coated with medicated wine put it on the skin, every day 3-5 time, 10 days courses for the treatment of.Matched group: with administration group under identical time and environment, uses the medicine (example hydrochloric acid terbinafine spray, griseofulvin etc.) of other treatment tinea alba, every day 3-5 time, 10 days courses for the treatment of.And observe simultaneously, record the natural on-off cycles of hair growth situation of every group patient.Curative effect situation criterion: cure: white macula disappears, and grows not only black but also dense hair, depilation phenomenon disappears.Effective: to grow some hairs, but also there is white macula a little.Invalid: white macula phenomenon is not eased even more seriously or the later stage recurs again.Wherein effective percentage comprise cure and effective.
Result is as shown in table 1:
Table 1
efficacy analysis:as can be seen from Table 1, use tinea capitis (tinea alba) external of embodiment 5 gained to rub the experimental group being coated with medicated wine with the hands and only have 2 people invalid, and matched group is invalid up to 34 people.And use tinea capitis (tinea alba) external of embodiment 5 gained to rub the cure rate of painting medicated wine with the hands up to 80%, total effective rate reaches 99%, and the cure rate of matched group only reaches 59%.Experiment show to use tinea capitis (tinea alba) external of embodiment 5 gained to rub with the hands and be coated with medicated wine compared with using the medicine of other treatment tinea alba, its curative effect increases substantially, and cure rate significantly promotes.
During taking, self-induction symptom variation is as shown in table 2:
Table 2
Significantly can find out from table 2, use tinea capitis (tinea alba) external of the embodiment of the present invention 5 gained to rub with the hands and be coated with the effect highly significant of medicated wine for treatment tinea capitis (tinea alba), Most patients symptom after 6 courses for the treatment of of medication is clearly better.In administration group, Most patients is taking 10 days, and more than 55% white macula disappears, and without pruritus, sick becomes gloss, root of hair is sturdy.Malaise symptoms improves; Take 20 days, more than 72% disease is improved or is disappeared; Take 30 days, the white macula of more than 94% disappears, and some patients self-induction is fully recovered.Tinea capitis of the present invention (tinea alba) external is rubbed with the hands and is coated with that medicated wine has good blood circulation promoting and blood stasis dispelling, killing parasites for relieving itching, removing toxic substances are dispeled the wind, promotion of blood circulation, improve hair follicle nutrition, hair follicle stimulating growth, promote new effect sending out regeneration.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.All any amendments done within the spirit and principles in the present invention, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. the preparation method being coated with medicated wine is rubbed in tinea capitis external with the hands, it is characterized in that, takes off the raw material stating weight proportion: Retinervus Luffae Fructus 20 parts, Radix Saposhnikoviae 10 parts, Fructus Gardeniae 17 parts, Radix Platycodonis 9 parts, 10 parts, Pericarpium Zanthoxyli, fresh Flos Celosiae Cristatae 65 parts, Camphora 1.8 parts, Borneolum Syntheticum 2.1 parts, brandy 500 parts; Step is as follows:
(1) Retinervus Luffae Fructus, Radix Saposhnikoviae, Fructus Gardeniae, Radix Platycodonis and Pericarpium Zanthoxyli are put into airtight cotton bag, fresh Flos Celosiae Cristatae tears up, and is together placed in airtight non iron container, adds brandy, and 12-18 days is soaked in sealing, and every day shakes 3-6 time; The concentration of brandy is 55 °-65 °;
(2) add proper honey to stir, continue fermentation 12-18 days, filter and remove residue, get upper strata clarification medicated liquor; The consumption of Mel is the 5%-7% of brandy quality;
(3) Camphora and Borneolum Syntheticum are ground, join in the medicated liquor of step (2) gained, sterile packaged.
2. preparation method according to claim 1, is characterized in that: the concentration of step (1) brandy is 60 °.
3. preparation method according to claim 1, is characterized in that: step (1) every day shakes 5 times.
4. preparation method according to claim 1, is characterized in that: step (1) sealing immersion 15 days.
5. preparation method according to claim 1, is characterized in that: the consumption of step (2) Mel is 6% of brandy quality.
6. preparation method according to claim 1, is characterized in that: step (2) fermentation 15 days.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264585A (en) * | 2000-01-01 | 2000-08-30 | 姚红军 | Exterior-applied Chinese-medicinal liniment for treating alopecia areata, seborrheic alopecia and bald |
| CN101342251A (en) * | 2008-08-29 | 2009-01-14 | 李金伟 | Externally used medicament for treating scald head |
| CN101716282A (en) * | 2009-12-23 | 2010-06-02 | 泰一和浦（北京）中医药研究院有限公司 | External Chinese medicinal composition with functions of hair loss prevention, hair strengthening and hair protection and preparation method thereof |
| CN102106943A (en) * | 2011-02-23 | 2011-06-29 | 徐海彬 | Liniment for treating alopecia and preparation method thereof |
| CN103495074A (en) * | 2013-08-26 | 2014-01-08 | 许其树 | Traditional Chinese medicine composition for treating favus of the scalp |
| CN103784508A (en) * | 2012-12-23 | 2014-05-14 | 徐化利 | Chinese medicinal formula for promoting hair growth |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP3908245B2 (en) * | 2004-08-06 | 2007-04-25 | ピアス株式会社 | Hair nourishing agent |
| JP2013193985A (en) * | 2012-03-19 | 2013-09-30 | Kao Corp | Hair tonic |
-
2014
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264585A (en) * | 2000-01-01 | 2000-08-30 | 姚红军 | Exterior-applied Chinese-medicinal liniment for treating alopecia areata, seborrheic alopecia and bald |
| CN101342251A (en) * | 2008-08-29 | 2009-01-14 | 李金伟 | Externally used medicament for treating scald head |
| CN101716282A (en) * | 2009-12-23 | 2010-06-02 | 泰一和浦（北京）中医药研究院有限公司 | External Chinese medicinal composition with functions of hair loss prevention, hair strengthening and hair protection and preparation method thereof |
| CN102106943A (en) * | 2011-02-23 | 2011-06-29 | 徐海彬 | Liniment for treating alopecia and preparation method thereof |
| CN103784508A (en) * | 2012-12-23 | 2014-05-14 | 徐化利 | Chinese medicinal formula for promoting hair growth |
| CN103495074A (en) * | 2013-08-26 | 2014-01-08 | 许其树 | Traditional Chinese medicine composition for treating favus of the scalp |
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