CN104161193A - Feed for improving breed capability of cyprinoids - Google Patents
Feed for improving breed capability of cyprinoids Download PDFInfo
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- CN104161193A CN104161193A CN201410322053.5A CN201410322053A CN104161193A CN 104161193 A CN104161193 A CN 104161193A CN 201410322053 A CN201410322053 A CN 201410322053A CN 104161193 A CN104161193 A CN 104161193A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
Abstract
The invention provides a feed for improving breed capability of cyprinoids. The materials of the feed comprise choline chloride, inositol, vitamin C, fish meal, soybean meal, bran, monocalcium phosphate, yeast powder, sodium alginate, methionine, threonine, salt, copper lysine, manganese sulfate and a traditional Chinese medicine additive prepared from mangnolia officinalis, eupatorium fortunei, companumoea root, suchow mosla herb, gentiana macrophylla, Chinese sage herb, radix paeoniae alba, parasitic loranthus, Chinese yam, franzenbach rhubarb root and rhizome, galangal, caulis polygoni multiflori, radix pseudostellariae, anisetree bark, asparagus cochinchinensis, pepperweed seed, radix stemonae and cistanche deserticola. When cyprinoids are fed with the feed provided by the invention, the breed capability of the cyprinoids can be improved, the immunity and disease-resistant accommodative strength of the bodies of the cyprinoids are enhanced without any toxic or side effects or any harm to the human bodies.
Description
Technical field
The present invention relates to field of feed, relate in particular to a kind of for improving the feed of carp production performance.
background technology
Carp another name carp cripple, carp, formal name used at school
cyprinus carpio, be under the jurisdiction of Cypriniformes Cyprinidae, be that Asia originates in temperate zone fresh water fish, like living in the rivers and creeks of warm lake on Plain or sluggish flow.Carp is the same with most fresh-water fishes to be belonged to without stomach fingerling, and enteron aisle is carefully short, and rate of metabolism is fast, therefore eating habit is for eating less diligent food.Carp is the omnivorousness demersal fishes of high-output stress-resistance, is one of traditional freshwater aquiculture kind of China, is also to cultivate in the world one of fish the most widely.Because its delicious meat is delicate, thorn is few, moderate cost, nutritious, very popular, have the good reputation of " first of chinese carp ".
In recent years, along with the high density intensivization development of aquaculture, the breaking out to culture fishery and brought massive losses on a large scale of disease.And the current antibiotic generally using has the drawbacks such as animal immunizing power, polluted water and the medicament residue of reduction.Antibiotic a large amount of use can cause that the water environment degradation, soil pollution in aquaculture old liberated area is serious, pathogenic microorganism produces drug resistance, aquatic products quality declines, the residual a series of serious problems such as exceed standard of medicine.Therefore, seek can substitute antibiotics green feed additive be current culture fishery urgent problem.
Chinese herbal medicine natural plants additive is a kind of green feed additive with bright prospects, it have natural, efficient, toxic and side effect is little, the resistance to the action of a drug not significantly, aboundresources and the advantage such as performance is various, when improving aquatic livestock production performance and efficiency of feed utilization, there is again immunoregulation effect, and can fully guarantee the health of human body, having medical and trophism double action concurrently, is that chemical synthesis feed addictive is incomparable.Improve the production performance of cultured fishes, strengthen immunity and the disease-resistant adjusting power of fish body simultaneously, taking to rely mainly on prevention is to make the not sick or few sick key factor of fish.
Natural plants contains abundant organic principle, wherein the multiple compounds such as plant polyose, flavonoids can participate in the various physiological metabolisms of body, has to regulate immunity of organism, suppress tumour, delay senility, hypoglycemic, radioresistance, anti-bacteria and anti-virus, adjusting blood fat, improve the several functions such as the speed of growth.Natural plant extracts (flavonoids, polysaccharide) is just shown up prominently in the application in aquatic products field, and it has become focus as the research and development of Novel fish feed addictive in China.
The present invention takes full advantage of medical and the trophism double action that Chinese herbal feed additive has, a kind of feed that contains Chinese herbal feed additive has been proposed, by giving this feed of carp feeding, can improve the production performance of fish, strengthen immunity and the disease-resistant adjusting power of fish body, and it can not bring any toxic and side effect, to human body without any injury.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of feed for improving the Chinese herbal feed additive of carp production performance and containing this feed addictive, by this feed of feeding, can improve the production performance of carp, strengthen immunity and the disease-resistant adjusting power of fish body, and it can not bring any toxic and side effect, to human body without any injury.
For solving the problems of the technologies described above, the invention provides a kind ofly for improving the Chinese herbal feed additive of carp production performance, its bulk drug comprises the bark of official magnolia, eupatorium, Companumoea root, suchow mosla herb, bark of ash, salvia chinensis, the root of herbaceous peony, parasitic loranthus, Chinese yam, franzenbach rhubarb root and rhizome, galangal, the vine of multiflower knotweed, radix pseudostellariae, anisetree bark, asparagus fern, lepidium seed, the tuber of stemona, saline cistanche and the coptis.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bark of official magnolia 10 weight portion～20 weight portions, eupatorium 10 weight portion～20 weight portions, Companumoea root 20 weight portion～30 weight portions, suchow mosla herb 15 weight portion～25 weight portions, bark of ash 25 weight portion～35 weight portions, salvia chinensis 15 weight portion～25 weight portions, the root of herbaceous peony 20 weight portion～30 weight portions, parasitic loranthus 25 weight portion～35 weight portions, Chinese yam 25 weight portion～35 weight portions, franzenbach rhubarb root and rhizome 25 weight portion～35 weight portions, galangal 10 weight portion～20 weight portions, the vine of multiflower knotweed 20 weight portion～30 weight portions, radix pseudostellariae 35 weight portion～45 weight portions, anisetree bark 15 weight portion～25 weight portions, asparagus fern 30 weight portion～40 weight portions, lepidium seed 20 weight portion～30 weight portions, the tuber of stemona 25 weight portion～35 weight portions, saline cistanche 20 weight portion～30 weight portions and the coptis 35 weight portion～45 weight portions.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bark of official magnolia 13 weight portion～17 weight portions, eupatorium 13 weight portion～17 weight portions, Companumoea root 23 weight portion～27 weight portions, suchow mosla herb 18 weight portion～22 weight portions, bark of ash 28 weight portion～32 weight portions, salvia chinensis 18 weight portion～22 weight portions, the root of herbaceous peony 23 weight portion～27 weight portions, parasitic loranthus 28 weight portion～32 weight portions, Chinese yam 28 weight portion～32 weight portions, franzenbach rhubarb root and rhizome 28 weight portion～32 weight portions, galangal 13 weight portion～17 weight portions, the vine of multiflower knotweed 23 weight portion～27 weight portions, radix pseudostellariae 38 weight portion～42 weight portions, anisetree bark 18 weight portion～22 weight portions, asparagus fern 33 weight portion～37 weight portions, lepidium seed 23 weight portion～27 weight portions, the tuber of stemona 28 weight portion～32 weight portions, saline cistanche 23 weight portion～27 weight portions and the coptis 38 weight portion～42 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese herbal feed additive, be specially each bulk drug of described Chinese herbal feed additive is uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, add the water with respect to 4 ~ 6 times of powder qualities, soak 4 ~ 8 hours, then decoct 2 ~ 4 hours, concoction is poured out, again add the water with respect to 2 ~ 4 times of powder qualities, decoct 1 hour ~ 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive.
It is a kind of for improving the feed of carp production performance that the present invention also provides, and its raw material comprises above-mentioned for improving Chinese herbal feed additive, Choline Chloride, inositol, vitamin C, fish meal, dregs of beans, wheat bran, calcium dihydrogen phosphate, dusty yeast, sodium alginate, methionine, threonine, salt, Copper lysinate and the manganese sulfate of carp production performance.
Wherein, the weight portion of described each raw material is respectively described Chinese herbal feed additive 10 weight portion～20 weight portions, Choline Chloride 0.2 weight portion～0.5 weight portion, inositol 0.2 weight portion～0.5 weight portion, vitamin C 0.2 weight portion～0.5 weight portion, fish meal 35 weight portion～45 weight portions, dregs of beans 20 weight portion～30 weight portions, wheat bran 15 weight portion～25 weight portions, calcium dihydrogen phosphate 1.5 weight portion～2.5 weight portions, dusty yeast 3 weight portion～5 weight portions, sodium alginate 0.5 weight portion～1 weight portion, methionine 0.3 weight portion～0.6 weight portion, threonine 0.3 weight portion～0.6 weight portion, salt 0.5 weight portion～1 weight portion, Copper lysinate 0.1 weight portion～0.3 weight portion, manganese sulfate 0.1 weight portion～0.3 weight portion.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, prepares described Chinese herbal feed additive according to method above;
Second step, it is even that the Chinese herbal feed additive that the first step is obtained and other each components in described feed are sent into stirrer for mixing in proportion;
The 3rd step, the material mixing carries out modified, and temperature is controlled at 90 ~ 95 ℃, and modulating time 55 ~ 65 seconds is granulated subsequently, and cooling, pellet composition is cooling, and temperature is controlled at 20 ~ 25 ℃, packing.
Beneficial effect of the present invention:
The invention provides the feed for improving the Chinese herbal feed additive of carp production performance and containing this feed addictive, by this feed of feeding, can improve the production performance of carp, strengthen immunity and the disease-resistant adjusting power of fish body, and it can not bring any toxic and side effect, to human body without any injury.
The specific embodiment
The invention provides a kind ofly for improving the Chinese herbal feed additive of carp production performance, its bulk drug comprises the bark of official magnolia, eupatorium, Companumoea root, suchow mosla herb, bark of ash, salvia chinensis, the root of herbaceous peony, parasitic loranthus, Chinese yam, franzenbach rhubarb root and rhizome, galangal, the vine of multiflower knotweed, radix pseudostellariae, anisetree bark, asparagus fern, lepidium seed, the tuber of stemona, saline cistanche and the coptis.
Further, described Chinese herbal feed additive only consists of above-mentioned raw materials medicine.
The pharmacology of described each bulk drug is as follows:
The bark of official magnolia: bitter, pungent, warm in nature, return the spleen channel; Stomach warp; Large intestine channel, has promoting the circulation of qi and disappears long-pending; Eliminating dampness is except full; The effect of relieving asthma, cures mainly stagnation of QI due to dyspepsia; Abdominal distention constipation; Damp retention in middle-jiao, gastral cavity ruffian is vomited and diarrhoea; Phlegm is stopped up the circulation of vital energy in the wrong direction; The fullness sensation in chest card such as breath with cough.
Eupatorium: taste is pungent, property is flat, returns spleen, stomach, lung channel, has expelling summer-heat and damp, ward off dirty and in effect, cure mainly summer-heat and damp, fever and chills headache, accumulates in moistening, gastral cavity ruffian is not hungry, n and V is sweet greasy in mouthful, disappears and truly waits card.
Companumoea root: latin name
radix campanumoea javanicae, be the root of Campanulaceae leopard platymiscium Campanumoea javanica and leopard, taste is sweet, and property is flat, returns lung, the spleen channel, have strengthening the spleen and replenishing qi, tonify the lung to relieve cough, the effect of lactogenesis, cures mainly the empty internal injury of labor, and the deficiency of vital energy is weak, palpitaition, hidrosis, splenasthenic diarrhea, leukorrhea, milk is rare, the cards such as insufficiency of the spleen cough.
Suchow mosla herb: warm in nature, taste is pungent, has dispelling summer-heat to relieve superficies syndrome, the effect of regulating qi-flowing for relieving pain, cures mainly flu, heatstroke, eruptive disease, peratodynia, the cards such as abscess of throat.
Bark of ash: latin name
gentianae Macrophyllae Radix, taste is pungent, bitter, and cold nature is returned stomach warp, Liver Channel, gallbladder channel, has wines used as antirheumatic, relaxing muscles and tendons network, the effect of clearind deficient heat, cures mainly arthralgia due to wind-dampness, the contraction of muscle arteries and veins, joint is ached, afternoon tidal fever, the cards such as infantile malnutrition heating.
Salvia chinensis: the herb of Labiatae clary Salvia chinensis, Latin literary fame
salvia, taste is pungent, bitter, cold nature, have promoting blood circulation and removing blood stasis, clearing heat and promoting diuresis, the effect of mass dissipating and swelling eliminating, cures mainly dysmenorrhoea, under humid tropics, cirrhosis, liver cancer, has blood in stool, jaundice with damp-heat pathogen, treating rheumatic ostealgia, falling the swollen card that waits of injuring.
The root of herbaceous peony: latin name
paeoniae Radix Alba, bitter, acid, cool in nature, enter liver, the spleen channel, there is nourishing blood and liver, slow middle pain relieving, astringe yin is received the effect of sweat, cures mainly chest abdomen pain over the hypochondriac region, rushes down dysentery stomachache, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, is with inferior card.
Parasitic loranthus: bitter, sweet, property is flat, enters liver, kidney channel, have the effect of filling liver kidney, strengthening the bones and muscles, wines used as antirheumatic, antiabortive unit, for the soreness of waist pain due to kidney deficiency and liver, muscles and bones impotence is soft, the foot and knee being feeble, kidney deficiency and liver, essence and blood is empty to be lost, the fetal irritability of liability to be abortion, the cards such as waist abdomen pain.
Chinese yam: latin name
dioscoreae rhizoma, taste is sweet, property is flat, enters lung, spleen, stomach warp, has tonifying spleen nourishing the stomach, beneficial lung reinforces the kidney, the effect of nourishing Yin and promoting production of body fluid, cure mainly weakness of the spleen and the stomach, the card such as it is poor that the food of the dysfunction of the spleen in transport is received less, the vexed diarrhoea of gastral cavity.
Franzenbach rhubarb root and rhizome: latin name
radix et Rhizome Rhei Franzenbachii, be the root and rhizome of polygonaceae plant rheum rhabarbarum, bitter; Cold in nature, return stomach; Large intestine channel, has the removing toxic substances of purging heat; The effect of the cool blood stasis of blood, cures mainly jaundice with damp-heat pathogen; Dysentery; Through closing stomachache; Hematemesis and epistaxis; Fall and beat stasis of blood pain; The carbuncle serious case of furuncle that swells; The erosion of mucous membrane in the oral cavity; The cards such as burn and scald.
Galangal: taste is pungent, hot in nature, return spleen, stomach warp, there is warming stomach for dispelling cold, the effect of the pain relieving that helps digestion.For coldness and pain in the epigastrium, gastrofrigid vomiting, the cards such as belch acid regurgitation.
The vine of multiflower knotweed: taste is sweet, property is flat, and the thoughts of returning home, Liver Channel, have nourishing blood and tranquilization, and the effect of dispelling wind and removing obstruction in the meridians, cures mainly insomnia and dreamful sleep, deficiency of blood bodily pain, arthralgia due to wind-dampness; The cards such as pruitus.
Radix pseudostellariae: sweet, the micro-hardship of taste, property is flat, enters spleen, lung channel, has air making-up and spleen enlivening, the effect that moistening lung is promoted the production of body fluid, for the few burnout of food of deficiency-weakness of spleen-QI, deficiency of stomach-Yin, the beneficial temper of energy, nourishing stomach-YIN, many for the deficiency syndrome of the lung cough caused by dryness of deficiency of vital energy Tianjin wound and palpitaition egersis, abnormal heat sweat, can nourishing generate fluid.
Anisetree bark: latin name
magnoliaceae, taste is micro-pungent, puckery, warm in nature, returns bladder, kidney channel, have dispel rheumatism, the effect of promoting qi circulation and relieving pain, cure mainly the cards such as arthralgia due to wind-dampness, qi-stagnating abdominalgia, married woman's bellyache in menstrual period.
Asparagus fern: taste is sweet, bitter, cold in nature, returns lung, kidney channel, has nourishing yin to moisten dryness, the effect that clearing lung-heat is promoted the production of body fluid, cures mainly cough caused by dryness-heat, and deficiency of Yin labor is coughed, fire excess from yin deficiency, the abscess of throat of seminal emission, premature ejaculation and flaring up of deficient fire that kidney essense is not solid, pyreticosis Tianjin wound is thirsty, the interior heat cards such as the dry constipation of intestines of quenching one's thirst.
Lepidium seed: taste is pungent, hardship, cold in nature, return lung channel, the heart channel of Hang-Shaoyin, Liver Channel, stomach warp, urinary bladder channel, there is purging the lung of pathogenic fire sending down abnormally ascending, eliminating phlegm and relieving asthma, inducing diuresis for removing edema, let out by evil effect, cure mainly the dyspnea and cough with excessive sputum that sputum is stopped up lung, lung carbuncle, oedema, chest abdomen ponding, difficult urination, chronic cor pulmonale, the card such as breathing heavily of heart failure is swollen, scrofula tuberculosis.
The tuber of stemona: taste is sweet, bitter, slightly warm in nature enters lung channel, have and moisten the lung and relieve the cough, the effect of delousing desinsection, tuber of stemona temperature embellishes but not dry, and property is kept and is not walked, the merit that has out again drop-down gas, be mainly used in new all coughing for a long time, be especially suitable for the hot chronic cough person of labor, the modern times are used for preventing and treating the cough of chronic bronchitis, the dry cough of pulmonary tuberculosis, the cards such as pertussis.
Saline cistanche: be the fleshy stem of Orobanchaceae Cistanche deserticola Vegetable meat desert cistanche and Cistanche tubulosa, latin name
herba cistanches, taste is sweet, salty, warm in nature, enters kidney, large intestine channel, there are kidney-replenishing, benefiting essence-blood, the effect relaxing bowel, for decline of kidney-YANG, the impotence and premature ejaculation of asthenia of essence and blood, infertile, soreness of waist and knee joint, Hiccough and deaf, frequent micturition urine number, the intestines of the suffering from a deficiency of the kidney deficiency of blood in dry and postpartum, the cards such as constipation that body fluid deficiency after being ill.
The coptis: bitter, cold in nature, enter the heart, lung, courage, stomach, large intestine channel, there is heat-clearing and damp-drying drug, purging intense heat and detonicating, the effect of cooling blood for improving eyesight, is usually used in treating the fire of removing the heart-fire warp, the dysphoria and insomnia that internal heat is prosperous, and the high fever coma of warm heat disease, the card such as vexed, thirsty.
In described Chinese medicine, the weight portion of each bulk drug is respectively the bark of official magnolia 10 weight portion～20 weight portions, eupatorium 10 weight portion～20 weight portions, Companumoea root 20 weight portion～30 weight portions, suchow mosla herb 15 weight portion～25 weight portions, bark of ash 25 weight portion～35 weight portions, salvia chinensis 15 weight portion～25 weight portions, the root of herbaceous peony 20 weight portion～30 weight portions, parasitic loranthus 25 weight portion～35 weight portions, Chinese yam 25 weight portion～35 weight portions, franzenbach rhubarb root and rhizome 25 weight portion～35 weight portions, galangal 10 weight portion～20 weight portions, the vine of multiflower knotweed 20 weight portion～30 weight portions, radix pseudostellariae 35 weight portion～45 weight portions, anisetree bark 15 weight portion～25 weight portions, asparagus fern 30 weight portion～40 weight portions, lepidium seed 20 weight portion～30 weight portions, the tuber of stemona 25 weight portion～35 weight portions, saline cistanche 20 weight portion～30 weight portions and the coptis 35 weight portion～45 weight portions.
Further preferably, in described Chinese medicine, the weight portion of each bulk drug is respectively the bark of official magnolia 13 weight portion～17 weight portions, eupatorium 13 weight portion～17 weight portions, Companumoea root 23 weight portion～27 weight portions, suchow mosla herb 18 weight portion～22 weight portions, bark of ash 28 weight portion～32 weight portions, salvia chinensis 18 weight portion～22 weight portions, the root of herbaceous peony 23 weight portion～27 weight portions, parasitic loranthus 28 weight portion～32 weight portions, Chinese yam 28 weight portion～32 weight portions, franzenbach rhubarb root and rhizome 28 weight portion～32 weight portions, galangal 13 weight portion～17 weight portions, the vine of multiflower knotweed 23 weight portion～27 weight portions, radix pseudostellariae 38 weight portion～42 weight portions, anisetree bark 18 weight portion～22 weight portions, asparagus fern 33 weight portion～37 weight portions, lepidium seed 23 weight portion～27 weight portions, the tuber of stemona 28 weight portion～32 weight portions, saline cistanche 23 weight portion～27 weight portions and the coptis 38 weight portion～42 weight portions.
Most preferably, in described Chinese medicine, the weight portion of each bulk drug is respectively the bark of official magnolia 15 weight portions, eupatorium 15 weight portions, Companumoea root 25 weight portions, suchow mosla herb 20 weight portions, bark of ash 30 weight portions, salvia chinensis 20 weight portions, the root of herbaceous peony 25 weight portions, parasitic loranthus 30 weight portions, Chinese yam 30 weight portions, franzenbach rhubarb root and rhizome 30 weight portions, galangal 15 weight portions, the vine of multiflower knotweed 25 weight portions, radix pseudostellariae 40 weight portions, anisetree bark 20 weight portions, asparagus fern 35 weight portions, lepidium seed 25 weight portions, the tuber of stemona 30 weight portions, saline cistanche 25 weight portions and the coptis 40 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese herbal feed additive, be specially each bulk drug of described Chinese herbal feed additive is uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, add the water with respect to 4 ~ 6 times of powder qualities, soak 4 ~ 8 hours, then decoct 2 ~ 4 hours, concoction is poured out, again add the water with respect to 2 ~ 4 times of powder qualities, decoct 1 hour ~ 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive.
It is a kind of for improving the feed of carp production performance that the present invention also provides, and its raw material comprises above-mentioned for improving Chinese herbal feed additive, Choline Chloride, inositol, vitamin C, fish meal, dregs of beans, wheat bran, calcium dihydrogen phosphate, dusty yeast, sodium alginate, methionine, threonine, salt, Copper lysinate and the manganese sulfate of carp production performance.
The weight portion of described each raw material is respectively described Chinese herbal feed additive 10 weight portion～20 weight portions, Choline Chloride 0.2 weight portion～0.5 weight portion, inositol 0.2 weight portion～0.5 weight portion, vitamin C 0.2 weight portion～0.5 weight portion, fish meal 35 weight portion～45 weight portions, dregs of beans 20 weight portion～30 weight portions, wheat bran 15 weight portion～25 weight portions, calcium dihydrogen phosphate 1.5 weight portion～2.5 weight portions, dusty yeast 3 weight portion～5 weight portions, sodium alginate 0.5 weight portion～1 weight portion, methionine 0.3 weight portion～0.6 weight portion, threonine 0.3 weight portion～0.6 weight portion, salt 0.5 weight portion～1 weight portion, Copper lysinate 0.1 weight portion～0.3 weight portion, manganese sulfate 0.1 weight portion～0.3 weight portion.
Further, the weight portion of described each raw material is respectively described Chinese herbal feed additive 15 weight portions, Choline Chloride 0.3 weight portion, inositol 0.3 weight portion, vitamin C 0.3 weight portion, fish meal 40 weight portions, dregs of beans 25 weight portions, wheat bran 20 weight portions, calcium dihydrogen phosphate 2 weight portions, dusty yeast 4 weight portions, sodium alginate 0.8 weight portion, methionine 0.5 weight portion, threonine 0.5 weight portion, salt 1 weight portion, Copper lysinate 0.2 weight portion, manganese sulfate 0.2 weight portion.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, prepares described Chinese herbal feed additive according to method above;
Second step, it is even that the Chinese herbal feed additive that the first step is obtained and other each components in described feed are sent into stirrer for mixing in proportion;
The 3rd step, the material mixing carries out modified, and temperature is controlled at 90 ~ 95 ℃, and modulating time 55 ~ 65 seconds is granulated subsequently, and cooling, pellet composition is cooling, and temperature is controlled at 20 ~ 25 ℃, packing.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese herbal feed additive 1
Bark of official magnolia 15g, eupatorium 15g, Companumoea root 25g, suchow mosla herb 20g, bark of ash 30g, salvia chinensis 20g, root of herbaceous peony 25g, parasitic loranthus 30g, Chinese yam 30g, franzenbach rhubarb root and rhizome 30g, galangal 15g, vine of multiflower knotweed 25g, radix pseudostellariae 40g, anisetree bark 20g, asparagus fern 35g, lepidium seed 25g, tuber of stemona 30g, saline cistanche 25g and coptis 40g are uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, the water that adds 2.5kg, soak 6 hours, then decoct 3 hours, concoction is poured out, the water that again adds 1.5kg, decoct 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive 1.
Embodiment 2 Chinese herbal feed additives 2
Bark of official magnolia 13g, eupatorium 13g, Companumoea root 23g, suchow mosla herb 18g, bark of ash 28g, salvia chinensis 18g, root of herbaceous peony 23g, parasitic loranthus 28g, Chinese yam 28g, franzenbach rhubarb root and rhizome 28g, galangal 13g, vine of multiflower knotweed 23g, radix pseudostellariae 38g, anisetree bark 18g, asparagus fern 33g, lepidium seed 23g, tuber of stemona 28g, saline cistanche 23g and coptis 38g are uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, the water that adds 2.5kg, soak 6 hours, then decoct 3 hours, concoction is poured out, the water that again adds 1.5kg, decoct 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive 2.
Embodiment 3 Chinese herbal feed additives 3
Bark of official magnolia 17g, eupatorium 17g, Companumoea root 27g, suchow mosla herb 22g, bark of ash 32g, salvia chinensis 22g, root of herbaceous peony 27g, parasitic loranthus 32g, Chinese yam 32g, franzenbach rhubarb root and rhizome 32g, galangal 17g, vine of multiflower knotweed 27g, radix pseudostellariae 42g, anisetree bark 22g, asparagus fern 37g, lepidium seed 27g, tuber of stemona 32g, saline cistanche 27g and coptis 42g are uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, the water that adds 2.5kg, soak 6 hours, then decoct 3 hours, concoction is poured out, the water that again adds 1.5kg, decoct 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive 3.
Embodiment 4 toxicology tests
Acute toxicity test
With reference to < < medicine registration management way > > and < < Chinese medicine, natural drug studies on acute toxicity technological guidance principle > > requirement, mouse stomach (ig) the administration the acute toxicity tests of the Chinese herbal feed additive 1 of the embodiment of the present invention 1 preparation is as follows: under maximum administration capacity and maximum administration concentration condition, after mouse ig Chinese herbal feed additive 213.16g of the present invention (crude drug)/kg, animal shows the phenomenons such as activity reduces to some extent, gradually recover subsequently normal.Test 40 routine animals without death.After administration, after approximately 1 hour, mouse behavior, movable basic recovery are normally.In the observation period of 14 days, body weight gain is normal afterwards, shows no obvious abnormalities symptom.
Long term toxicity test
With reference to < < medicine registration management way > > and < < Chinese medicine, natural drug long term toxicity investigative technique guideline > > requirement, carried out the long term toxicity test research of rodent SD rat oral gavage administration, result is as follows:
120 of SD rats, test minute high dose group (25.2 (crude drug) g/kg), middle dosage group (12.6g (crude drug)/kg), low dose group (8.9g (crude drug)/kg) and blank group (purified water), 30 of every treated animals, male and female half and half.Method of administration is gastric infusion, and once a day, administration is 6 days weekly, and the test period is 24 weeks.Each test group 1/3 animal should be observed the variation of 4 week convalescence.General status, changes of weight, food ration, blood cytology and biochemical index, gross anatomy and the histopathological examination of animal by the long term toxicity test requirement of new drug, have been observed.
In administration 24 time-of-weeks, it is abnormal that the high, medium and low dosage treated animal of medicine is showed no evident act, and ordinary circumstance is good, during administration without animal dead.Hematology, blood biochemical, prothrombin time, organ coefficient and the Histopathology of 1 month after administration 3 months, 6 months and drug withdrawal checked.Hematology, prothrombin time result show, all find no the Novel presentation relevant to medicine; Blood biochemical is learned result and is shown, the glutamic-pyruvic transaminase of administration animal after 3 months reduces, administration after 6 months creatinine reduce, after administration, sodium, potassium, chlorine ion concentration slightly fluctuate, and recover normal during to convalescence, think this result abiology meaning; Organ coefficient result shows, administration is buck low dose group liver coefficient, Spleen coefficient increase after 6 months, during convalescence, respectively organize each organ coefficient of rat and dirty brain than all in normal range (NR), think that this possibility of result and medicine are relevant through hepatic metabolism, this reaction is reversible with recoverable; Histopathologic examination's result shows, to each important organ of rat, all there is not the pathological change relevant to medicine in this medicine, although each treated animal is degree of taking a favourable turn interstitial lung inflammation all, there is slight fatty liver in indivedual animals, because the pathological change of administration group does not obviously surpass control group, and in conjunction with hematological indices, blood biochemical, learning the experimental results such as index, gross anatomy observation and organ coefficient comprehensively thinks, above-mentioned pathological change and medicine are without obvious correlation, and other each organs and tissues is showed no obvious abnormalities change.
Through to 6 months long term toxicity tests of rat, have no and obviously relevant serious toxicity reaction of medicine, to evaluate on the whole, Chinese medicine preparation of the present invention can safety applications, and this medicine non-toxic is 8.9g crude drug/kg.
The preparation of embodiment 5 feeds 1
The Chinese herbal feed additive 1.5kg that embodiment 1 is obtained, Choline Chloride 0.03kg, inositol 0.03kg, vitamin C 0.03kg, fish meal 4kg, dregs of beans 2.5kg, wheat bran 2kg, calcium dihydrogen phosphate 0.2kg, dusty yeast 0.4kg, sodium alginate 0.08kg, methionine 0.05kg, threonine 0.05kg, salt 0.1kg, Copper lysinate 0.02kg, it is even that manganese sulfate 0.02kg sends into stirrer for mixing, the material mixing is carried out modified, temperature is controlled at 95 ℃, modulating time 65 seconds, granulate subsequently, cooling, pellet composition is cooling, temperature is controlled at 20 ℃, packing.
The preparation of comparative example 1 feed 2
By Choline Chloride 0.03kg, inositol 0.03kg, vitamin C 0.03kg, fish meal 4kg, dregs of beans 2.5kg, wheat bran 2kg, calcium dihydrogen phosphate 0.2kg, dusty yeast 0.4kg, sodium alginate 0.08kg, methionine 0.05kg, threonine 0.05kg, salt 0.1kg, Copper lysinate 0.02kg, that manganese sulfate 0.02kg sends into stirrer for mixing is even, the material mixing is carried out modified, temperature is controlled at 95 ℃, modulating time 65 seconds, granulate subsequently, cooling, pellet composition is cooling, temperature is controlled at 20 ℃, packing.
Embodiment 6 raising data
Feed:
Test group adopts the feed 1 of embodiment 5 preparations, and control group adopts the feed 2 of comparative example 1 preparation.
Experiment fish and feeding and management:
Healthy 1 carp in age (No. 3, Beijing) fingerling, is provided by steep River Reservoir culture experiment base.Experiment fish is totally 200 tails, within random minute, supports in 2 aquariums, and adaptability was raised and train after 2 weeks, started experiment.An aquarium is for test group, and another aquarium is for control group, every group of 100 tail carps.Raise 120 d.The water temperature of experimental session, at 19.4 ~ 26.8 ℃, has circulation filter pump and inflator pump, refreshes the water periodically and cleans filter pulp, maintains dissolved oxygen at 5.7 ~ 7. 9 mg/L, and pH value, 6. 1 ~ 8. 0, is controlled ammonia (NH
3) concentration be less than 0. 02 mg/L, control nitrite (NO
2 -) content be less than 0.20 mg/L.
Growth performance is measured
In experiment, start and finish (front 1 d that experiment finishes stops throwing something and feeding), with electronic balance, claim fish body weight (being accurate to 0. 01 g), calculate feed coefficient, feed conversion rate, the relative weight gain rate and instantaneous rate of body weight gain.
During feed coefficient (FCR)=cultivation, throw in feed gross weight/(cultivation finishes macrura reevesii gross weight-beginning macrura reevesii gross weight)
Feed conversion rate (FUE)=cultivation fish has a net increase of weight/food consumption total amount * 100%
The relative weight gain rate (RWG)=cultivation fish has a net increase of weight/cultivation and starts macrura reevesii gross weight * 100%
Instantaneous rate of body weight gain (SGR)=(lnW
t-lnW
0)/t * 100%, W in formula
tfor cultivation finishes macrura reevesii weight; W
0for cultivation starts macrura reevesii weight; T is feeding time (d).
Statistical disposition
Experimental data represents with " average ± standard error ", difference statistics between organizing with t check.
Result
Carp growth Performance Ratio, the results are shown in Table 1.
Table 1 carp growth Performance Ratio
As can be seen from Table 1, test group feed coefficient declines than control group, has significant difference (P<0. 05).The instantaneous rate of body weight gain of test group improves 70. 83% than control group, and Chinese herbal feed additive is to the growth promoting effect of carp remarkable (P<0. 05).
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (9)
1. for improving a Chinese herbal feed additive for carp production performance, it is characterized in that: bulk drug comprises the bark of official magnolia, eupatorium, Companumoea root, suchow mosla herb, bark of ash, salvia chinensis, the root of herbaceous peony, parasitic loranthus, Chinese yam, franzenbach rhubarb root and rhizome, galangal, the vine of multiflower knotweed, radix pseudostellariae, anisetree bark, asparagus fern, lepidium seed, the tuber of stemona, saline cistanche and the coptis.
2. Chinese herbal feed additive as claimed in claim 1, it is characterized in that: the weight portion of each bulk drug is respectively the bark of official magnolia 10 weight portion～20 weight portions, eupatorium 10 weight portion～20 weight portions, Companumoea root 20 weight portion～30 weight portions, suchow mosla herb 15 weight portion～25 weight portions, bark of ash 25 weight portion～35 weight portions, salvia chinensis 15 weight portion～25 weight portions, the root of herbaceous peony 20 weight portion～30 weight portions, parasitic loranthus 25 weight portion～35 weight portions, Chinese yam 25 weight portion～35 weight portions, franzenbach rhubarb root and rhizome 25 weight portion～35 weight portions, galangal 10 weight portion～20 weight portions, the vine of multiflower knotweed 20 weight portion～30 weight portions, radix pseudostellariae 35 weight portion～45 weight portions, anisetree bark 15 weight portion～25 weight portions, asparagus fern 30 weight portion～40 weight portions, lepidium seed 20 weight portion～30 weight portions, the tuber of stemona 25 weight portion～35 weight portions, saline cistanche 20 weight portion～30 weight portions and the coptis 35 weight portion～45 weight portions.
3. Chinese herbal feed additive as claimed in claim 1 or 2, it is characterized in that: the weight portion of each bulk drug is respectively the bark of official magnolia 13 weight portion～17 weight portions, eupatorium 13 weight portion～17 weight portions, Companumoea root 23 weight portion～27 weight portions, suchow mosla herb 18 weight portion～22 weight portions, bark of ash 28 weight portion～32 weight portions, salvia chinensis 18 weight portion～22 weight portions, the root of herbaceous peony 23 weight portion～27 weight portions, parasitic loranthus 28 weight portion～32 weight portions, Chinese yam 28 weight portion～32 weight portions, franzenbach rhubarb root and rhizome 28 weight portion～32 weight portions, galangal 13 weight portion～17 weight portions, the vine of multiflower knotweed 23 weight portion～27 weight portions, radix pseudostellariae 38 weight portion～42 weight portions, anisetree bark 18 weight portion～22 weight portions, asparagus fern 33 weight portion～37 weight portions, lepidium seed 23 weight portion～27 weight portions, the tuber of stemona 28 weight portion～32 weight portions, saline cistanche 23 weight portion～27 weight portions and the coptis 38 weight portion～42 weight portions.
4. the preparation method of Chinese herbal feed additive described in claim 1 to 4, it is characterized in that: each bulk drug of described Chinese herbal feed additive is uniformly mixed, send in pulverizer and pulverize, be screened into 20 object powder, put into subsequently saucepan, add the water with respect to 4 ~ 6 times of powder qualities, soak 4 ~ 8 hours, then decoct 2 ~ 4 hours, concoction is poured out, again add the water with respect to 2 ~ 4 times of powder qualities, decoct 1 hour ~ 2 hours, filter, the concoction obtaining and the concoction obtaining above mixing will be filtered, reduced pressure concentration is except anhydrating, dry, pulverize, be screened into 20 object powder, obtain described Chinese herbal feed additive.
5. for improving a feed for carp production performance, it is characterized in that: raw material comprises Chinese herbal feed additive, Choline Chloride, inositol, vitamin C, fish meal, dregs of beans, wheat bran, calcium dihydrogen phosphate, dusty yeast, sodium alginate, methionine, threonine, salt, Copper lysinate and the manganese sulfate for improving carp production performance.
6. feed as claimed in claim 5, is characterized in that: the bulk drug of described Chinese herbal feed additive comprises the bark of official magnolia, eupatorium, Companumoea root, suchow mosla herb, bark of ash, salvia chinensis, the root of herbaceous peony, parasitic loranthus, Chinese yam, franzenbach rhubarb root and rhizome, galangal, the vine of multiflower knotweed, radix pseudostellariae, anisetree bark, asparagus fern, lepidium seed, the tuber of stemona, saline cistanche and the coptis.
7. the feed as described in claim 5 or 6, it is characterized in that: the weight portion of each bulk drug of described Chinese herbal feed additive is respectively the bark of official magnolia 10 weight portion～20 weight portions, eupatorium 10 weight portion～20 weight portions, Companumoea root 20 weight portion～30 weight portions, suchow mosla herb 15 weight portion～25 weight portions, bark of ash 25 weight portion～35 weight portions, salvia chinensis 15 weight portion～25 weight portions, the root of herbaceous peony 20 weight portion～30 weight portions, parasitic loranthus 25 weight portion～35 weight portions, Chinese yam 25 weight portion～35 weight portions, franzenbach rhubarb root and rhizome 25 weight portion～35 weight portions, galangal 10 weight portion～20 weight portions, the vine of multiflower knotweed 20 weight portion～30 weight portions, radix pseudostellariae 35 weight portion～45 weight portions, anisetree bark 15 weight portion～25 weight portions, asparagus fern 30 weight portion～40 weight portions, lepidium seed 20 weight portion～30 weight portions, the tuber of stemona 25 weight portion～35 weight portions, saline cistanche 20 weight portion～30 weight portions and the coptis 35 weight portion～45 weight portions.
8. the feed as described in claim 5 to 7, it is characterized in that: the weight portion of described each raw material is respectively described Chinese herbal feed additive 10 weight portion～20 weight portions, Choline Chloride 0.2 weight portion～0.5 weight portion, inositol 0.2 weight portion～0.5 weight portion, vitamin C 0.2 weight portion～0.5 weight portion, fish meal 35 weight portion～45 weight portions, dregs of beans 20 weight portion～30 weight portions, wheat bran 15 weight portion～25 weight portions, calcium dihydrogen phosphate 1.5 weight portion～2.5 weight portions, dusty yeast 3 weight portion～5 weight portions, sodium alginate 0.5 weight portion～1 weight portion, methionine 0.3 weight portion～0.6 weight portion, threonine 0.3 weight portion～0.6 weight portion, salt 0.5 weight portion～1 weight portion, Copper lysinate 0.1 weight portion～0.3 weight portion, manganese sulfate 0.1 weight portion～0.3 weight portion.
9. the preparation method of feed described in claim 5 to 8, is characterized in that:
The first step, prepares described Chinese herbal feed additive in accordance with the method for claim 4;
Second step, it is even that the Chinese herbal feed additive that the first step is obtained and other each components in described feed are sent into stirrer for mixing in proportion;
The 3rd step, the material mixing carries out modified, and temperature is controlled at 90 ~ 95 ℃, and modulating time 55 ~ 65 seconds is granulated subsequently, and cooling, pellet composition is cooling, and temperature is controlled at 20 ~ 25 ℃, packing.
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