CN104147455A - Preparation for treating ocular myasthenia gravis - Google Patents
Preparation for treating ocular myasthenia gravis Download PDFInfo
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- CN104147455A CN104147455A CN201410425742.9A CN201410425742A CN104147455A CN 104147455 A CN104147455 A CN 104147455A CN 201410425742 A CN201410425742 A CN 201410425742A CN 104147455 A CN104147455 A CN 104147455A
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Abstract
The invention relates to improvement of a traditional Chinese medicine preparation for treating ocular myasthenia gravis and provides a traditional Chinese medicine preparation, which is low in cost and is good in curative effect, for treating the ocular myasthenia gravis. A technical scheme in the invention is described as follows: the traditional Chinese medicine preparation consists following components: 15-60 parts of radix codonopsis, 20-60 parts of astragalus membranaceus, 5-10 parts of mix-fried radix glycyrrhizae, 10-20 parts of atractylodes macrocephala koidz, 10-30 parts of poria cocos, 10-20 parts of rhizoma cimicifugae, 10-20 parts of bupleurum, 10-15 parts of fructus lycii, 10-30 parts of angelica sinensis and 10-15 parts of pericarpium citri reticulatae 10-25 parts of semen cuscutae, 10-30 parts of coix seeds, 10-20 parts of malt, 10-15 parts of Chinese yam and 10-20 parts of pulp of cornus.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of improvement of Chinese medicine preparation for the treatment of ocular myasthenia gravis.
Background technology
Myasthenia gravis is a kind of acquired autoimmune disease of neuromuscular junction propagation function obstacle, impaired mainly due to acetylcholinergic receptor on nerve-muscle postsynaptic membrane due to.Often with blepharoptosis, primary symptom of diplopia, clinical ocular type, whole body type, acute severe type, tardy serious symptom type, amyotrophy type 5 types of being divided into of doctor trained in Western medicine, wherein ocular type is through treatment prognosis the best, the methods such as hormone, immunosuppressant, anticholinergic medicine, plasmapheresis, thymusectomy that adopt at present more, but these methods courses for the treatment of is long, expense is high, side effect is large, and easily recurrence, doctor trained in Western medicine does not have a kind of effective therapy up to now.Myasthenia gravis belongs to the traditional Chinese medical science " myopathy " category, because deficiency of spleen-QI and stomach-QI mostly is common pattern of syndrome, for myasthenia gravis (doctor trained in Western medicine typing: ocular type; Chinese medical discrimination: syndrome of deficiency of spleen qi and stomach qi), disease sees that order eyeball rotates ineffective with the ptosis or companion stravismus, diplopia, and companion sees extremity asthenia, and deficiency of QI with disinclination to talk, breathes hard uncomfortable in chest, indigestion and loss of appetite lack of appetite, pale tongue, white and thin fur, deep pulse person's curative effect is good.
Summary of the invention
The kind that the object of this invention is to provide a kind of with low cost, good effect, taking effect property is treated the Chinese medicine preparation of ocular myasthenia gravis.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of ocular myasthenia gravis, it is to be made up of the material of following weight proportioning: 20～60 parts of the Radixs Astragali, 15～60 parts of Radix Codonopsis, 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～30 parts, Poria, 10～20 parts of Rhizoma Cimicifugaes, 10～20 parts of Radix Bupleuri, 10～15 parts of Fructus Lycii, 10～30 parts of Radix Angelicae Sinensis, 10～15 parts of Pericarpium Citri Reticulataes, 10～25 parts of Semen Cuscutae, 10～30 parts of Semen Coiciss, 10～20 parts, Fructus Hordei Germinatus, 10～15 parts of Rhizomadioscoreae, 10～20 parts of Fructus Corni, 5～10 parts of Radix Glycyrrhizae Preparatas.
Preferably, the medicament for the treatment of ocular myasthenia gravis of the present invention is to be made up of the material of following weight proportioning: 30 parts of the Radixs Astragali, 25 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 15 parts of Rhizoma Cimicifugaes, 12 parts of Radix Bupleuri, 12 parts of Fructus Lycii, 15 parts of Radix Angelicae Sinensis, 12 parts of Pericarpium Citri Reticulataes, 20 parts of Semen Cuscutae, 15 parts of Semen Coiciss, 15 parts, Fructus Hordei Germinatus, 10 parts of Rhizomadioscoreae, 10 parts of Fructus Corni, 5 parts of Radix Glycyrrhizae Preparatas.
Preferably, the medicament for the treatment of ocular myasthenia gravis of the present invention is to be made up of the material of following weight proportioning: 24 parts of Radix Codonopsis, 31 parts of the Radixs Astragali, 5 parts of Radix Glycyrrhizae Preparatas, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 21 parts, Poria, 15 parts of Rhizoma Cimicifugaes, 12 parts of Radix Bupleuri, 12 parts of Fructus Lycii, 15 parts of Radix Angelicae Sinensis, 12 parts of Pericarpium Citri Reticulataes, 21 parts of Semen Cuscutae, 18 parts of Semen Coiciss, 15 parts, Fructus Hordei Germinatus, 10 parts of Rhizomadioscoreae, 17 parts of Fructus Corni.
More preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.
Whole compositions of the medicament for the treatment of ocular myasthenia gravis of the present invention are all natural materials, and safety is better, and curative effect is clear and definite, are suitable for large-scale promotion clinically.
Detailed description of the invention
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for the present invention instead of limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment 1 decoction of the present invention
Take 30 grams of the Radixs Astragali, 25 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams, Poria, 15 grams of Rhizoma Cimicifugaes, 12 grams of Radix Bupleuri, 12 grams of Fructus Lycii, 15 grams of Radix Angelicae Sinensis, 12 grams of Pericarpium Citri Reticulataes, 20 grams of Semen Cuscutae, 15 grams of Semen Coiciss, 15 grams, Fructus Hordei Germinatus, 10 grams of Rhizomadioscoreae, 10 grams of Fructus Corni, 5 grams of Radix Glycyrrhizae Preparatas, add 1000 milliliters, water, and cold water is fried boiling 20 minutes, filter, obtain decoction of the present invention.
Embodiment 2 decoction of the present invention
Take 30 grams of the Radixs Astragali, 25 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams, Poria, 15 grams of Rhizoma Cimicifugaes, 12 grams of Radix Bupleuri, 12 grams of Fructus Lycii, 15 grams of Radix Angelicae Sinensis, 12 grams of Pericarpium Citri Reticulataes, 20 grams of Semen Cuscutae, 15 grams of Semen Coiciss, 15 grams, Fructus Hordei Germinatus, 10 grams of Rhizomadioscoreae, 10 grams of Fructus Corni, 5 grams of Radix Glycyrrhizae Preparatas, add 1000 milliliters, water, and cold water is fried boiling 20 minutes, filter, obtain decoction of the present invention.
Experimental example
Chinese medicine of the present invention is extensive in clinical practice for many years.Treat 25 routine ocular myasthenia gravis patients, make a definite diagnosis with go to the hospital neostigmine or the edrophonium chloride test positive in Jun Jing county.Wherein male 9 examples, the age is in 20-60 year, and average 35 years old, female's 16 examples, the age was 20-40 year, average 28 years old.
Use the decoction making in embodiment 1 to treat, 1 dose of every day, day takes 4 times, each 150～200ml.
Curative effect determinate standard:
Cure: the unable symptom and sign of the eye muscle such as blepharoptosis, diplopia disappears nothing morbidity in 1 year.
Effective: clinical symptoms is obviously improved, slight blepharoptosis or diplopia, slight on daily life impact;
Effective: clinical symptoms is improved, and to a certain degree affects daily life;
Invalid: clinical symptoms is unchanged or increase the weight of.
Through the treatment of a course for the treatment of (2 months), 25 routine ocular myasthenia gravis patient 23 examples are cured, and 1 routine patient is effective, and 1 routine patient is effective, and during whole treatment, does not observe obvious untoward reaction.
Claims (4)
1. a medicament for the treatment of ocular myasthenia gravis, is characterized in that, it is to be made up of the material of following weight proportioning: 15～60 parts of Radix Codonopsis, 20～60 parts of the Radixs Astragali, 5～10 parts of Radix Glycyrrhizae Preparatas, 10～20 parts of the Rhizoma Atractylodis Macrocephalaes, 10～30 parts, Poria, 10～20 parts of Rhizoma Cimicifugaes, 10～20 parts of Radix Bupleuri, 10～15 parts of Fructus Lycii, 10～30 parts of Radix Angelicae Sinensis, 10～15 parts of Pericarpium Citri Reticulataes, 5～10 parts of Radix Glycyrrhizae Preparatas, 10～25 parts of Semen Cuscutae, 10～30 parts of Semen Coiciss, 10～20 parts, Fructus Hordei Germinatus, 10～15 parts of Rhizomadioscoreae, 10～20 parts of Fructus Corni.
2. the medicament for the treatment of ocular myasthenia gravis according to claim 1, is characterized in that, it is to be made up of the material of following weight proportioning: 25 parts of Radix Codonopsis, 30 parts of the Radixs Astragali,, 15 parts of 5 parts of Rhizoma Atractylodis Macrocephalaes of Radix Glycyrrhizae Preparata, 20 parts, Poria, 15 parts of Rhizoma Cimicifugaes, 12 parts of Radix Bupleuri, 12 parts of Fructus Lycii, 15 parts of Radix Angelicae Sinensis, 12 parts of Pericarpium Citri Reticulataes, 20 parts of Semen Cuscutae, 15 parts of Semen Coiciss, 15 parts, Fructus Hordei Germinatus, 10 parts of Rhizomadioscoreae, 10 parts of Fructus Corni.
3. the medicament for the treatment of ocular myasthenia gravis according to claim 1, is characterized in that, it is to be made up of the material of following weight proportioning: 24 parts of Radix Codonopsis, 31 parts of the Radixs Astragali, 5 parts of Radix Glycyrrhizae Preparatas, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 21 parts, Poria, 15 parts of Rhizoma Cimicifugaes, 12 parts of Radix Bupleuri, 12 parts of Fructus Lycii, 15 parts of Radix Angelicae Sinensis, 12 parts of Pericarpium Citri Reticulataes, 21 parts of Semen Cuscutae, 18 parts of Semen Coiciss, 15 parts, Fructus Hordei Germinatus, 10 parts of Rhizomadioscoreae, 17 parts of Fructus Corni.
4. the medicament for the treatment of ocular myasthenia gravis according to claim 1, is characterized in that, described medicament can be tablet, dispersible tablet, capsule or decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410425742.9A CN104147455A (en) | 2014-08-27 | 2014-08-27 | Preparation for treating ocular myasthenia gravis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410425742.9A CN104147455A (en) | 2014-08-27 | 2014-08-27 | Preparation for treating ocular myasthenia gravis |
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| CN104147455A true CN104147455A (en) | 2014-11-19 |
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| CN201410425742.9A Pending CN104147455A (en) | 2014-08-27 | 2014-08-27 | Preparation for treating ocular myasthenia gravis |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288561A (en) * | 2015-11-30 | 2016-02-03 | 吕翠云 | Traditional Chinese medicine composition for treating eye myasthenia gravis |
| CN105497334A (en) * | 2015-12-31 | 2016-04-20 | 张鹏 | Chinese patent medicine for treating myasthenia gravis and preparation method thereof |
| CN106236917A (en) * | 2016-09-07 | 2016-12-21 | 吴永峰 | A kind of Chinese medicine treating myasthenia gravis |
| CN108653526A (en) * | 2018-07-13 | 2018-10-16 | 乞国艳 | The prescription of Chinese traditional treatment myasthenia gravis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1966033A (en) * | 2006-09-26 | 2007-05-23 | 方利泉 | Medicament for treating eyelid ptosis and myasthenia gravis and method for preparing same |
-
2014
- 2014-08-27 CN CN201410425742.9A patent/CN104147455A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1966033A (en) * | 2006-09-26 | 2007-05-23 | 方利泉 | Medicament for treating eyelid ptosis and myasthenia gravis and method for preparing same |
Non-Patent Citations (2)
| Title |
|---|
| 刘建萌: "补中益气汤重用黄芪治疗重症肌无力25例临床观察", 《辽宁中医杂志》 * |
| 孙伯青: "加味补中益气汤治疗"眼肌型重症肌无力"", 《甘肃中医》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288561A (en) * | 2015-11-30 | 2016-02-03 | 吕翠云 | Traditional Chinese medicine composition for treating eye myasthenia gravis |
| CN105497334A (en) * | 2015-12-31 | 2016-04-20 | 张鹏 | Chinese patent medicine for treating myasthenia gravis and preparation method thereof |
| CN106236917A (en) * | 2016-09-07 | 2016-12-21 | 吴永峰 | A kind of Chinese medicine treating myasthenia gravis |
| CN108653526A (en) * | 2018-07-13 | 2018-10-16 | 乞国艳 | The prescription of Chinese traditional treatment myasthenia gravis |
| CN108653526B (en) * | 2018-07-13 | 2021-03-16 | 乞国艳 | Traditional Chinese medicine formula for treating myasthenia gravis |
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