CN104147387A - Traditional Chinese medicinal preparation for treating cerebral thrombosis - Google Patents
Traditional Chinese medicinal preparation for treating cerebral thrombosis Download PDFInfo
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- CN104147387A CN104147387A CN201410397758.3A CN201410397758A CN104147387A CN 104147387 A CN104147387 A CN 104147387A CN 201410397758 A CN201410397758 A CN 201410397758A CN 104147387 A CN104147387 A CN 104147387A
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Abstract
The invention relates to a traditional Chinese medicinal preparation, and in particular to a traditional Chinese medicinal preparation for treating cerebral thrombosis and a preparation method thereof. The traditional Chinese medicinal preparation is prepared from the following Chinese herbal medicinal materials by weight: 10-15 parts of the root of kudzu vine, 10-15 parts of rhizoma gastrodiae, 10-15 parts of ginkgo fruit, 10-15 parts of Chinese angelica, 10-15 parts of Ligusticum wallichii, 10-15 parts of Erigeron breviscapus, 5-7 parts of hawthorn, 1-2 parts of garlic, 3-5 parts of peach kernel and 3-5 parts of the root of red-rooted salvia. The preparation method is as below: weighing traditional Chinese medicinal raw materials according to the prescription and adding the raw materials into a container; adding water to immerge the materials and soaking for 25 to 30 min; then adding water to a level 2-4 cm higher than the material surface; decocting to a boiling state with strong fire and then decocting with slow fire for 30-40 min, and taking a filtrate; and then adding water to a level 2-4 cm higher than the material surface, decocting to a boiling state with strong fire and then decocting with slow fire for 30-40 min; then removing the slag to obtain the filtrate; and merging the filtrates. The preparation has the characteristics of clearing and activating the channels and collaterals, promoting blood circulation to remove blood stasis, expanding brain blood vessel, reducing vascular resistance, improving cerebral circulation, increasing blood flow, and improving the immune function of the patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of cerebral thrombosis and preparation method thereof.
Background technology
Cerebral thrombosis is a kind of common cerebrovascular disease, it is mainly because the tremulous pulse of supply brain makes luminal stenosis, obturation because of atherosclerosis etc. self pathological changes, or form thrombosis on narrow basis, cause the local acute blood flow interruption of brain, hypoxic-ischemic and softening downright bad, occur corresponding neurological symptom.The morbidity crowd of cerebral thrombosis is mainly 45 years old above middle-aged and elderly people, and wherein male is slightly more than women.Clinical manifestation after cerebral thrombosis morbidity is mainly facial hemiparalysis, slurred speech, numbness of hands and feet, severe patient hemiplegia, can't take care of oneself.Once patient's morbidity, the probability of fatality rate and trouble sequela is very high.
Doctor trained in Western medicine thinks, the origin cause of formation of cerebral thrombosis is endothelial cell damage, the change of the change of blood fluidised form and blood itself, blood is condensed in blood vessel or blood in some composition there is the phenomenon of sticky collection.The Western medicine of existing treatment cerebral thrombosis mainly take thrombolytic, dilute blood, prevent that cerebral edema is as main, although these medicines can play the effect for the treatment of to a certain extent, all exist long, the problem such as the slow and cure rate of taking effect the is low course for the treatment of.
The traditional Chinese medical science thinks, the main cause of cerebral thrombosis morbidity be patient's deficiency of qi and blood usually, the heart, liver, the dirty imbalance of YIN and YANG of kidney three, and QI-blood circulation is obstructed, and skin muscle arteries and veins loses in moistening foster and causes.Differential diagnosis in tcm thinks that extreme hyperactivity of the liver-yang, obstruction of collateral caused by windphlegm, the hot internal organs reality of expectorant, blood stasis due to qi deficiency, stirring of wind due to deficiency of YIN, wind-fire cover key, phlegm-fire and close that key, phlegm-damp cover key, vigour decays for main reason.
At present, the Western medicine for the treatment of cerebral thrombosis is a lot, but most drug therapeutic effect is poor, and also has the shortcomings such as treatment cost is high, side effect is large, even affects patient health when serious.
Summary of the invention
In order to solve above the deficiencies in the prior art, the Chinese medicine of the treatment cerebral thrombosis that the invention provides a kind of short treating period, instant effect, can cure, has wide potential applicability in clinical practice.
A kind of Chinese medicine preparation for the treatment of cerebral thrombosis of the present invention, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Puerariae 10-15 part, Rhizoma Gastrodiae 10-15 part, ginkgo nut 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Chuanxiong 10-15 part, Herba Erigerontis 10-15 part, Fructus Crataegi 5-7 part, Bulbus Allii 1-2 part, Semen Persicae 3-5 part, Radix Salviae Miltiorrhizae 3-5 part.
Preferred version is as follows: according to parts by weight meter, formulated by following raw material of Chinese medicine: 13 parts of Radix Puerariaes, 13 parts, Rhizoma Gastrodiae, 13 parts of ginkgo nuts, 13 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 13 parts of Herba Erigerontiss, 6 parts of Fructus Crataegis, 1 part, Bulbus Allii, 4 parts, Semen Persicae, 4 parts of Radix Salviae Miltiorrhizaes.
A kind of preparation method for the treatment of the Chinese medicine preparation of cerebral thrombosis, according to formula, take raw material of Chinese medicine and join in container, adding water and cover powder and soak 25-30 minute, then adding water and do not have powder 2-4 centimetre, decoct with high heat to boiling and use again slow fire boiling 30-40 minute instead, get filtrate; And then add water and do not have powder 2-4 centimetre, decoct with high heat to boiling and use again slow fire boiling 30-40 minute instead, then to remove slag and get filtrate, twice filtrate merges.
While taking, each 250ml, sooner or later respectively once.
The Chinese medicine of this treatment cerebral thrombosis has dispelling wind and removing obstruction in the collateral, blood circulation promoting and blood stasis dispelling, kidney tonifying marrow facilitating, promoting the circulation of QI to relieve pain, removing heat from blood, hemostasis, enhancing capillary resistance and improves the effect of vascular fragility.Within 30 days, be a course for the treatment of, symptom the lighter can cure 1 course for the treatment of, and severe one can be cured 2～3 courses for the treatment of.The effective percentage of this Chinese medicine reaches 100%, the feature that have that toxic and side effects is little, short treating period, instant effect, cure rate are high, does not recur after more.
Pharmacology analysis:
Radix Puerariae: can blood circulation promoting and blood stasis dispelling, mind tranquilizing and the heart calming, suppressing the hyperactive liver and subsiding YANG, be improved heart and brain circulation, the effect that increases cerebral blood flow and reduce blood pressure;
Rhizoma Gastrodiae: there is the effect of suppressing the hyperactive liver and subsiding YANG and relieving spasm by subduing liver-wind, can improve cerebral blood perfusion and improve brain microcirculation, blood pressure lowering, blood fat reducing, and can pain relieving spasmolytic;
Ginkgo nut: the flat sweet in the mouth of property is pained, enters lung kidney channel, the gas of astringing the lung, relieving asthma and cough, eliminates the phlegm, the effect such as cough-relieving, lung moistening, Dingchuan;
Radix Angelicae Sinensis: the function that having enriches blood invigorates blood circulation, removing blood stasis nourishes blood, can blood circulation promoting and blood stasis dispelling, can blood vessel dilating, all cards of blood deficiency; Menoxenia; Amenorrhea, dysmenorrhea; Lump in the abdomen knot is poly-, metrorrhagia; Asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome; Numbness of the skin, dryness of the intestine dyschezia; Heavy, ulcer sores after bloody dysentery; Injury from falling down;
Rhizoma Chuanxiong: have the function of vital energy regualting and blood circulation-promoting, can expand cardiovascular and cerebrovascular vessel, improve microcirculation, promote the recovery of brain function, pungent loose temperature is logical, can blood circulation promoting and blood stasis dispelling, and again can promoting the circulation of QI to relieve pain, for " the gas medicine in blood ", the sensible QI and blood effect of tool, therefore control the breast side of body, all pains of abdominal part of qi depression to blood stasis;
Herba Erigerontis: energy dredge the meridian passage and blood circulation promoting and blood stasis dispelling, expansion of cerebral vascular, reduction vascular resistance, improve cerebral circulation, increase heart and brain blood flow, improve immunologic function, cold in nature, micro-hardship, Gan Wenxin, have the effect of the removing toxic substances of being slightly cold, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, anti-inflammatory analgetic;
Fructus Crataegi: blood vessel dilating, increase cardiovascular and cerebrovascular vessel blood flow, reduce the effect of blood fat and slight blood pressure lowering, spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, include the materials such as saccharide, protein, fat, vitamin C, carotene, starch, malic acid, the acid of structure rafter, calcium and ferrum, there is the effect of blood fat reducing, blood pressure;
Bulbus Allii: acrid in the mouth warm in nature is flat; Enter taste lung meridian.Blood vessel dilating, increases cardiovascular and cerebrovascular vessel blood flow, reduces the effect of blood fat and slight blood pressure lowering;
Semen Persicae: lump in the abdomen caking, lung abscess acute appendicitis, tumbling down is grieved, amenorrhea dysmenorrhea, puerperal, the stasis of blood waited disease bitterly, benefiting QI for activating blood circulation, disperse blood stasis and dredge collateral, expansion cardiovascular and cerebrovascular vessel, blood fat reducing, bitter but sweet flavor and property are flat, can enter conscience large intestine, and blood circulation promoting and blood stasis dispelling effect is very wide, availablely control the various worn-out diseases of stagnation of blood stasis;
Radix Salviae Miltiorrhizae: bitter in the mouth, be slightly cold, enter the heart, Liver Channel.Promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind, relieving restlessness is calmed the nerves;
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.Energy dredge the meridian passage and blood circulation promoting and blood stasis dispelling, expansion of cerebral vascular, reduction vascular resistance, improve cerebral circulation, increases heart and brain blood flow, improves the feature of patient's immunologic function.
Efficacy evaluation:
Cure: symptom and sign disappears completely;
Effective: symptom and sign before alleviates;
Invalid: symptom and sign is front without improving with treatment.
Collect 100 routine cerebral thrombus patients, male 65 examples, female's 35 examples; Age 40-81 year, average 55 years old; 100 routine patients for the treatment of are divided into matched group 50 people and experimental group 50 people, and vertical shelves stay looks in addition Statistical Comparison, and matched group is treated with routine of western medicine, experimental group Drug therapy of the present invention, patient takes preparation of the present invention and treats, each 250ml, sooner or later each once, serve on 3 months.Statistical result is as follows:
Table 1: matched group curative effect situation
Table 2: experimental group curative effect situation
Clinical cure 48 examples, account for 96%; Effective 50 examples, invalid 0 example, total effective rate is 100%.
Below enumerate several model cases:
Case 1: Liu, man, 53 years old, ill 2 years of cerebral thrombosis, mouthful eye is crooked left, aphasia rope, takes medicine of the present invention after the course for the treatment of, and facial hemiparalysis symptom alleviates, and trick activity recovers, and also can speak, continue to take medicine after half a year, transference cure, follows up a case by regular visits to half a year, without recurrence.
Case 2: field, female, 66 years old, ill 1 year of cerebral thrombosis, right lower limb is lost consciousness, and the right hand yet activity is not agile, and in palm, there is cinerous cloud form speckle, take medicine of the present invention after 3 courses for the treatment of, trick activity recovers, and cinerous cloud form speckle disappears, continue to take medicine after half a year, transference cure, follows up a case by regular visits to half a year, without recurrence.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
Treat a Chinese medicine preparation for cerebral thrombosis, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: 10 parts of Radix Puerariaes, 10 parts, Rhizoma Gastrodiae, 10 parts of ginkgo nuts, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 10 parts of Herba Erigerontiss, 5 parts of Fructus Crataegis, 1 part, Bulbus Allii, 3 parts, Semen Persicae, 3 parts of Radix Salviae Miltiorrhizaes.
Embodiment 2:
Treat a Chinese medicine preparation for cerebral thrombosis, according to parts by weight meter, formulated by following raw material of Chinese medicine: 15 parts of Radix Puerariaes, 15 parts, Rhizoma Gastrodiae, 15 parts of ginkgo nuts, 5 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 15 parts of Herba Erigerontiss, 7 parts of Fructus Crataegis, 2 parts, Bulbus Allii, 5 parts, Semen Persicae, 5 parts of Radix Salviae Miltiorrhizaes.
Embodiment 3:
Treat a Chinese medicine preparation for cerebral thrombosis, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: 13 parts of Radix Puerariaes, 13 parts, Rhizoma Gastrodiae, 13 parts of ginkgo nuts, 13 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 13 parts of Herba Erigerontiss, 6 parts of Fructus Crataegis, 1 part, Bulbus Allii, 4 parts, Semen Persicae, 4 parts of Radix Salviae Miltiorrhizaes.
Embodiment 4:
Embodiment 1 prepares Chinese medicine preparation in accordance with the following methods: according to formula, take raw material of Chinese medicine and join in container, adding water and cover powder and soak 25 minutes, then adding water and do not have 2 centimetres of powder, decocting with high heat to boiling and use slow fire boiling instead 30 minutes again, getting filtrate; And then add water and do not have 2 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 30 minutes, then to remove slag and get filtrate, twice filtrate merges.
Embodiment 5:
Embodiment 2 prepares Chinese medicine preparation in accordance with the following methods: according to formula, take raw material of Chinese medicine and join in container, adding water and cover powder and soak 30 minutes, then adding water and do not have 4 centimetres of powder, decocting with high heat to boiling and use slow fire boiling instead 40 minutes again, getting filtrate; And then add water and do not have 4 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 40 minutes, then to remove slag and get filtrate, twice filtrate merges.
Embodiment 6:
Embodiment 3 prepares Chinese medicine preparation in accordance with the following methods: according to formula, take raw material of Chinese medicine and join in container, adding water and cover powder and soak 27 minutes, then adding water and do not have 3 centimetres of powder, decocting with high heat to boiling and use slow fire boiling instead 35 minutes again, getting filtrate; And then add water and do not have 3 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 35 minutes, then to remove slag and get filtrate, twice filtrate merges.
Claims (3)
1. a Chinese medicine preparation for the treatment of cerebral thrombosis, it is characterized in that: according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Puerariae 10-15 part, Rhizoma Gastrodiae 10-15 part, ginkgo nut 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Chuanxiong 10-15 part, Herba Erigerontis 10-15 part, Fructus Crataegi 5-7 part, Bulbus Allii 1-2 part, Semen Persicae 3-5 part, Radix Salviae Miltiorrhizae 3-5 part.
2. a kind of Chinese medicine preparation for the treatment of cerebral thrombosis according to claim 1, it is characterized in that: according to parts by weight meter, formulated by following raw material of Chinese medicine: 13 parts of Radix Puerariaes, 13 parts, Rhizoma Gastrodiae, 13 parts of ginkgo nuts, 13 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 13 parts of Herba Erigerontiss, 6 parts of Fructus Crataegis, 1 part, Bulbus Allii, 4 parts, Semen Persicae, 4 parts of Radix Salviae Miltiorrhizaes.
3. the preparation method of the Chinese medicine preparation of a treatment cerebral thrombosis claimed in claim 1, it is characterized in that: according to formula, take raw material of Chinese medicine and join in container, add water and cover powder immersion 25-30 minute, add again water and do not have powder 2-4 centimetre, decoct with high heat to boiling and use again slow fire boiling 30-40 minute instead, get filtrate; And then add water and do not have powder 2-4 centimetre, decoct with high heat to boiling and use again slow fire boiling 30-40 minute instead, then to remove slag and get filtrate, twice filtrate merges.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474301A (en) * | 2014-11-25 | 2015-04-01 | 孙莉莉 | Traditional Chinese medicine preparation for treating cerebral thrombosis and preparation method thereof |
| CN106138532A (en) * | 2016-08-04 | 2016-11-23 | 马畅 | The inducing resuscitation for the treatment of cerebral infarction is removed obstacles Chinese medicine and preparation method thereof |
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| CN1390594A (en) * | 2002-07-30 | 2003-01-15 | 成都国嘉药物研究所 | Mixture for improving blood circulation |
| CN1640484A (en) * | 2004-11-16 | 2005-07-20 | 安徽科创中药天然药物研究所有限责任公司 | Chinese medicine soft capsule Naodesheng and its preparing method |
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- 2014-08-13 CN CN201410397758.3A patent/CN104147387A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1390594A (en) * | 2002-07-30 | 2003-01-15 | 成都国嘉药物研究所 | Mixture for improving blood circulation |
| CN1640484A (en) * | 2004-11-16 | 2005-07-20 | 安徽科创中药天然药物研究所有限责任公司 | Chinese medicine soft capsule Naodesheng and its preparing method |
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| 牙韩华等: "脑血栓的溶栓治疗及中医治疗状况", 《右江民族医学院学报》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474301A (en) * | 2014-11-25 | 2015-04-01 | 孙莉莉 | Traditional Chinese medicine preparation for treating cerebral thrombosis and preparation method thereof |
| CN106138532A (en) * | 2016-08-04 | 2016-11-23 | 马畅 | The inducing resuscitation for the treatment of cerebral infarction is removed obstacles Chinese medicine and preparation method thereof |
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Application publication date: 20141119 |
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