CN104127857A - Fish oil soft capsule and preparation method thereof - Google Patents

Fish oil soft capsule and preparation method thereof Download PDF

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Publication number
CN104127857A
CN104127857A CN201410303291.1A CN201410303291A CN104127857A CN 104127857 A CN104127857 A CN 104127857A CN 201410303291 A CN201410303291 A CN 201410303291A CN 104127857 A CN104127857 A CN 104127857A
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Prior art keywords
parts
fish oil
soft capsule
preparation
content
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CN201410303291.1A
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Chinese (zh)
Inventor
孙伟楼
谢静莉
冯之涛
刘凌
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JIANGSU WEILOU BIOLOGICAL TECHNOLOGY Co Ltd
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JIANGSU WEILOU BIOLOGICAL TECHNOLOGY Co Ltd
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Priority to CN201410303291.1A priority Critical patent/CN104127857A/en
Publication of CN104127857A publication Critical patent/CN104127857A/en
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Abstract

The invention discloses a fish oil soft capsule and a preparation method thereof, and belongs to the field of medicinal and health food, and the fish oil soft capsule includes a content and a capsule shell; the contents includes the following components by weight: 60 to 100 parts of fish oil, 1-5 parts of vitamin C, 5-8 parts of vegetable oil, 2-4 parts of arginine, 1-2.5 parts of dihydroxy phenyl ethylamine, 2-5.5 parts of soybean protein powder, 3-6 parts of pectin, and 1-3 parts of beewax; the preparation method includes the following steps: (1) the content preparation; (2) the capsule shell preparation; and (3) the soft capsule preparation. The prepared fish oil soft capsule is free of fishy taste, convenient in carrying and eating, and long in shelf life cycle; and the fish oil soft capsule can play the medical and health care function after eating and can promote human health.

Description

A kind of fish oil soft capsule and preparation method thereof
Technical field
The present invention relates to a kind of fish oil soft capsule and preparation method thereof, belong to medicines and health protection field of food.
Background technology
Fish oil is the general designation of oily substance in fish body; it comprises body oil, liver oil and cerebrol; main fish oil is a kind of oils and fats extracting from greasiness Fish; being rich in ω-3 is polyunsaturated fatty acid; main composition is DHA(docosahexenoic acid) and EPA(eicosapentaenoic acid); DHA is a kind of special unsaturated fatty acid; there is the factor of activating brain cell; EPA is a kind of unsaturated fatty acid equally; contain the multiple sanguimotor protection factor that is easy to, therefore fish oil has antiinflammatory, regulates the health-care effecies such as blood fat.Fish oil under room temperature is liquid, has a fish like smell; Containing two keys, extremely responsive to light, heat and oxygen in DHA and EPA, conventionally need low temperature, lucifuge sealing to preserve, above-mentioned defect has restricted the application of fish oil aspect health care of food greatly.
Traditional fish oil has stench taste, in extractive process, the first step, first through deodorization processing, lacks necessary seal approach in subsequent process conventionally, causes the fish oil of preparation easily oxidized, functional component DHA and EPA in fish oil are ineffective, have reduced the nutritive value of fish oil.
Summary of the invention
The problem existing for above-mentioned prior art, the invention provides a kind of fish oil soft capsule and preparation method thereof, and the fish oil soft capsule of preparation is without fishlike smell, easy for carrying and eating, and the cycle of guaranteeing the quality is long; Medical treatment, the health-care effect that after edible, can bring into play fish oil, promote health.
To achieve these goals, a kind of fish oil soft capsule that the present invention adopts, comprises content and softgel shell, by weight, described content comprises following component, 60 ~ 100 parts, fish oil, 1 ~ 5 part of vitamin C, 5 ~ 8 parts of vegetable oil, arginase 12 ~ 4 part, 1 ~ 2.5 part, dihydroxy benzenes ethamine, 2 ~ 5.5 parts, soybean protein powder, 3 ~ 6 parts of pectin, 1 ~ 3 part, Cera Flava.
Further, the weight ratio of content and softgel shell is 60:1 ~ 3.
Preferably, fish oil is the one of tunny fish oil, salmon fish oil, sturgeon oil or pilchard oil.
Further, softgel shell comprises 20 ~ 50 parts, gelatin, 5 ~ 15 parts of glycerol, 10 ~ 20 parts of propolis, 10 ~ 50 parts, water.
Preferably, content comprises 75 parts, fish oil, 2 parts of vitamin Cs, 6 parts of vegetable oil, 3.5 parts of arginine, 1.7 parts, dihydroxy benzenes ethamine, 4 parts, soybean protein powder, 4.5 parts of pectin, 2 parts, Cera Flava; Described softgel shell comprises 35 parts, gelatin, 7 parts of glycerol, 30 parts, water, 14.5 parts of propolis.
The present invention also provides a kind of preparation method of fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 5 ~ 8 parts, 60 ~ 100 parts, fish oil, vegetable oil and be dissolved in 85 ~ 90% ethanol, in stirring, add arginase 12 ~ 4 part, 1 ~ 2.5 part, dihydroxy benzenes ethamine, 2 ~ 5.5 parts, soybean protein powder, 3 ~ 6 parts of pectin, 1 ~ 3 part, Cera Flava, under airtight condition, stir 2 ~ 5h, after leaving standstill 30 ~ 60min, solution filter obtains filter cake, and after washing, vacuum drying obtains capsule 's content;
(2) preparation of softgel shell: take by weight 20 ~ 50 parts, gelatin, 5 ~ 15 parts of glycerol, 10 ~ 20 parts of propolis, 10 ~ 50 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 30 ~ 45 DEG C of heat insulation tanks and be incubated after 1 ~ 4h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:1 ~ 3 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Preferably, in step (1), take 6.5 parts, 75 parts, fish oil, vegetable oil and be dissolved in 90% ethanol, in stirring, add 3.3 parts of arginine, 1.6 parts, dihydroxy benzenes ethamine, 3.5 parts, soybean protein powder, 4.2 parts of pectin, 1.6 parts, Cera Flava.
Further, the vacuum drying condition in step (1) is 40 ~ 50 DEG C of temperature, and pressure is 0.5 ~ 3MPa, and the time is 1 ~ 2.5h.
Preferably, in step (2), take 32 parts, gelatin, 7 parts of glycerol, 14 parts of propolis, 40 parts, water.
Preferably, in step (3), content and softgel shell carry out fill by the weight ratio of 60:1.8.
Fish oil soft capsule provided by the invention, by fish oil, vitamin C, vegetable oil, arginine, dihydroxy benzenes ethamine, soybean protein powder, pectin, Cera Flava component content thing, fish oil wherein has antiinflammatory, regulates effect of blood fat; Arginine can improve blood flow effectively, stops the formation of thrombosis, and the sickness rate that reduces the cardiovascular disease such as coronary heart disease, hypertension, myocardial infarction, arteriosclerosis is had to special effect; Dihydroxy benzenes ethamine, function is bowel relieving stomach, treats constipation, and has clearing heat and moistening lung, effect such as excessive thirst, replenishing essence marrow, alcoholic intoxication only; Soybean protein can reduce hypercholesterolemia patient's blood fat and the adverse effect of cholesterol to heart, the combined effect of foregoing thing, the effect that enters performance after human body and regulate blood fat.
The present invention makes softgel shell by gelatin, glycerol, propolis, water, can effectively stop fishlike smell volatilization, avoid affecting the edible of people, this fish oil soft capsule preparation method is simple, in preparation process, fish oil is in air-proof condition, avoided effective ingredient DHA(docosahexenoic acid in fish oil) and EPA(eicosapentaenoic acid) oxidation deactivation, medical, health-care effect is remarkable; Fish oil soft capsule of the present invention is easy for carrying and eating, and the cycle of guaranteeing the quality is long.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment mono-
A preparation method for fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 5 parts of 60 parts of tunny fish oils, vegetable oil and be dissolved in 85% ethanol, in stirring, add arginase 12 part, 1 part, dihydroxy benzenes ethamine, 2 parts, soybean protein powder, 3 parts of pectin, 1 part, Cera Flava, stirs 2h under airtight condition, and after standing 30min, solution filter obtains filter cake, after washing, be 40 DEG C in temperature, under the condition that pressure is 0.5MPa, after dry 2.5h, obtain capsule 's content;
(2) preparation of softgel shell: take by weight 20 parts, gelatin, 5 parts of glycerol, 10 parts of propolis, 10 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 30 DEG C of heat insulation tanks and be incubated after 1h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:1 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Embodiment bis-
A preparation method for fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 8 parts of 100 parts of salmon fish oil, vegetable oil and be dissolved in 90% ethanol, in stirring, add 4 parts of arginine, 2.5 parts, dihydroxy benzenes ethamine, 5.5 parts, soybean protein powder, 6 parts of pectin, 3 parts, Cera Flava, stirs 5h under airtight condition, and after standing 60min, solution filter obtains filter cake, after washing, be 50 DEG C in temperature, under the condition that pressure is 3MPa, after dry 1h, obtain capsule 's content;
(2) preparation of softgel shell: take by weight 50 parts, gelatin, 15 parts of glycerol, 20 parts of propolis, 50 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 45 DEG C of heat insulation tanks and be incubated after 4h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:3 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Embodiment tri-
A preparation method for fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 6.5 parts of 80 parts of sturgeon oils, vegetable oil and be dissolved in 87% ethanol, in stirring, add 3 parts of arginine, 1.8 parts, dihydroxy benzenes ethamine, 4 parts, soybean protein powder, 4.5 parts of pectin, 2 parts, Cera Flava, stirs 3.5h under airtight condition, and after standing 45min, solution filter obtains filter cake, after washing, be 45 DEG C in temperature, under the condition that pressure is 2MPa, after dry 1.5h, obtain capsule 's content;
(2) preparation of softgel shell: take by weight 35 parts, gelatin, 6 parts of glycerol, 15 parts of propolis, 30 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 37 DEG C of heat insulation tanks and be incubated after 2.5h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:2 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Embodiment tetra-
A preparation method for fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 6.5 parts of 75 parts of pilchard oils, vegetable oil and be dissolved in 90% ethanol, in stirring, add 3.3 parts of arginine, 1.6 parts, dihydroxy benzenes ethamine, 3.5 parts, soybean protein powder, 4.2 parts of pectin, 1.6 parts, Cera Flava, stirs 3h under airtight condition, and after standing 45min, solution filter obtains filter cake, after washing, be 42 DEG C in temperature, under the condition that pressure is 2.5MPa, after dry 1.6h, obtain capsule 's content;
(2) preparation of softgel shell: take by weight 32 parts, gelatin, 7 parts of glycerol, 14 parts of propolis, 40 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 36 DEG C of heat insulation tanks and be incubated after 3h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:1.8 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Embodiment five
A preparation method for fish oil soft capsule, comprises the following steps,
(1) preparation of content: take by weight 6 parts of 85 parts of salmon fish oil, vegetable oil and be dissolved in 85% ethanol, in stirring, add arginase 12 .5 part, 1.5 parts, dihydroxy benzenes ethamine, 4.5 parts, soybean protein powder, 4 parts of pectin, 1.5 parts, Cera Flava, stirs 3.5h under airtight condition, and after standing 45min, solution filter obtains filter cake, after washing, be 45 DEG C in temperature, under the condition that pressure is 0.5MPa, after dry 2.5h, obtain capsule 's content;
(2) preparation of softgel shell: take by weight 50 parts, gelatin, 5 parts of glycerol, 14 parts of propolis, 35 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 35 DEG C of heat insulation tanks and be incubated after 3.5h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:1.2 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
Fish oil prepared by the present invention in closed state, has been avoided functional component DHA and the EPA oxidation deactivation in fish oil in the course of processing, and the content of capsule comprises the effective ingredient of multiple adjusting blood fat simultaneously, after taking, can play good medical treatment, health-care effect.This fish oil soft capsule preparation process simple, capsule is easy for carrying and eating, the time of guaranteeing the quality is long.

Claims (10)

1. a fish oil soft capsule, comprises content and softgel shell, it is characterized in that, by weight, described content comprises following component, 60 ~ 100 parts, fish oil, 1 ~ 5 part of vitamin C, 5 ~ 8 parts of vegetable oil, arginase 12 ~ 4 part, 1 ~ 2.5 part, dihydroxy benzenes ethamine, 2 ~ 5.5 parts, soybean protein powder, 3 ~ 6 parts of pectin, 1 ~ 3 part, Cera Flava.
2. fish oil soft capsule according to claim 1, is characterized in that, described content and the weight ratio of softgel shell are 60:1 ~ 3.
3. fish oil soft capsule according to claim 1, is characterized in that, described fish oil is the one of tunny fish oil, salmon fish oil, sturgeon oil or pilchard oil.
4. fish oil soft capsule according to claim 1 and 2, is characterized in that, by weight, described softgel shell comprises 20 ~ 50 parts, gelatin, 5 ~ 15 parts of glycerol, 10 ~ 20 parts of propolis, 10 ~ 50 parts, water.
5. fish oil soft capsule according to claim 4, is characterized in that, by weight, described content comprises 75 parts, fish oil, 2 parts of vitamin Cs, 6 parts of vegetable oil, 3.5 parts of arginine, 1.7 parts, dihydroxy benzenes ethamine, 4 parts, soybean protein powder, 4.5 parts of pectin, 2 parts, Cera Flava; Described softgel shell comprises 35 parts, gelatin, 7 parts of glycerol, 30 parts, water, 14.5 parts of propolis.
6. a preparation method for fish oil soft capsule, is characterized in that, comprise the following steps,
(1) preparation of content: take by weight 5 ~ 8 parts, 60 ~ 100 parts, fish oil, vegetable oil and be dissolved in 85 ~ 90% ethanol, in stirring, add arginase 12 ~ 4 part, 1 ~ 2.5 part, dihydroxy benzenes ethamine, 2 ~ 5.5 parts, soybean protein powder, 3 ~ 6 parts of pectin, 1 ~ 3 part, Cera Flava, under airtight condition, stir 2 ~ 5h, after leaving standstill 30 ~ 60min, solution filter obtains filter cake, and after washing, vacuum drying obtains capsule 's content;
(2) preparation of softgel shell: take by weight 20 ~ 50 parts, gelatin, 5 ~ 15 parts of glycerol, 10 ~ 20 parts of propolis, 10 ~ 50 parts, water, in being placed in glue tank, heat up and be stirred to after thawing, obtain homogenizing glue, glue sieves, filters and to obtain refining glue, be placed in again 30 ~ 45 DEG C of heat insulation tanks and be incubated after 1 ~ 4h, refining glue is made to the softgel shell of soft capsule by capsule machine;
(3) preparation of soft capsule: the ratio that is 60:1 ~ 3 according to the weight ratio of content and softgel shell, step (1) is made to content and add in the softgel shell of step (2) by filling machine, make fish oil soft capsule.
7. the preparation method of fish oil soft capsule according to claim 6, it is characterized in that, by weight, in described step (1), taking 6.5 parts, 75 parts, fish oil, vegetable oil is dissolved in 90% ethanol, in stirring, add 3.3 parts of arginine, 1.6 parts, dihydroxy benzenes ethamine, 3.5 parts, soybean protein powder, 4.2 parts of pectin, 1.6 parts, Cera Flava.
8. according to the preparation method of the fish oil soft capsule described in claim 6 or 7, it is characterized in that, the vacuum drying condition in described step (1) is 40 ~ 50 DEG C of temperature, and pressure is 0.5 ~ 3MPa, and the time is 1 ~ 2.5h.
9. according to the preparation method of the fish oil soft capsule described in claim 6 or 7, it is characterized in that, by weight, in described step (2), take 32 parts, gelatin, 7 parts of glycerol, 14 parts of propolis, 40 parts, water.
10. the preparation method of fish oil soft capsule according to claim 6, is characterized in that, in described step (3), content and softgel shell carry out fill by the weight ratio of 60:1.8.
CN201410303291.1A 2014-06-30 2014-06-30 Fish oil soft capsule and preparation method thereof Pending CN104127857A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108175102A (en) * 2017-11-28 2018-06-19 芜湖市诺康生物科技有限公司 A kind of preparation method of cod liver oil soft capsule
CN110613137A (en) * 2019-09-30 2019-12-27 威海金思力生物科技股份有限公司 Fish oil soft capsule and preparation method thereof
CN110839881A (en) * 2019-11-26 2020-02-28 康道生物(南通)有限公司 Ganoderma lucidum spore oil lycopene soft capsule and preparation process thereof
CN112890197A (en) * 2021-03-10 2021-06-04 湖南文理学院 Fish oil product with health promotion effect

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108175102A (en) * 2017-11-28 2018-06-19 芜湖市诺康生物科技有限公司 A kind of preparation method of cod liver oil soft capsule
CN110613137A (en) * 2019-09-30 2019-12-27 威海金思力生物科技股份有限公司 Fish oil soft capsule and preparation method thereof
CN110839881A (en) * 2019-11-26 2020-02-28 康道生物(南通)有限公司 Ganoderma lucidum spore oil lycopene soft capsule and preparation process thereof
CN112890197A (en) * 2021-03-10 2021-06-04 湖南文理学院 Fish oil product with health promotion effect

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