CN104116885A - Composition for assisting hyperglycemic capsules and preparation method thereof - Google Patents
Composition for assisting hyperglycemic capsules and preparation method thereof Download PDFInfo
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- CN104116885A CN104116885A CN201410382144.8A CN201410382144A CN104116885A CN 104116885 A CN104116885 A CN 104116885A CN 201410382144 A CN201410382144 A CN 201410382144A CN 104116885 A CN104116885 A CN 104116885A
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Abstract
The invention relates to a composition for assisting hyperglycemic capsules and a preparation method thereof. The preparation method is characterized by comprising the following steps: weighing the following components in parts by weight: 13-22 parts of gingko leaf, 15-20 parts of kelp, 16-19 parts of mulberry, 14-19 parts of fructus lycii, 10-15 parts of chrysanthemum, 8-12 parts of yam, 3-8 parts of salviae miltiorrhizae and 4-10 parts of apocynum venetum, and preparing a medicinal liquid for later use by a traditional Chinese medical decoction method; combining the medicinal liquids, putting in a triple-effect vacuum high-energy evaporation concentrator, reducing pressure, heating to 80 DEG C, and concentrating to a thick liquid or paste; putting into a drying oven, heating to 60 DEG C, drying for 4 hours under a constant-temperature condition, crushing, screening and filling into capsules; and sterilizing to prepare a finished product.
Description
Technical field
The invention belongs to Chinese medicine health-care medicine technical field, particularly a kind of assembly of auxiliary hyperglycemic capsule and manufacture method.
Background technology
Hyperglycemia refer to when (sugar-free and any sugary food intake in 8 hours) blood glucose on an empty stomach higher than normal range 4.0-6.1mmol/L or after the meal two hours blood glucoses higher than 7.8mmol/L normal range.Under normal circumstances, human body can guarantee that the source of blood glucose and outlet keep balance, make blood glucose maintain certain level by hormonal regulation and this two large regulating system of neuroregulation.But under the combined effect of inherited genetic factors (as diabetes family history) and environmental factors (as irrational meals, obesity etc.), two large regulatory functions get muddled, and just there will be the rising of blood sugar level.Short time, disposable hyperglycemia to human body without grievous injury.Yet long-term hyperglycemia can make each histoorgan generation pathological changes of whole body, causes the generation of acute and chronic complication.As pancreatic function exhaustion, dehydration, electrolyte disturbance, malnutrition, resistance decline, impaired renal function, neuropathy, retinopathy etc.
Diabetes are the commonly encountered diseases that affect human health and life, belong to endocrine metabolism systemic disease, take hyperglycemia as outstanding feature, occur clinically excessive thirst, polyuria, polydipsia, polyphagia, tired, become thin, the performance such as glucose in urine.Blood sugar increasing, glucose in urine increases, and can cause osmotic diuresis, thereby causes the symptom of polyuria; Blood sugar increasing, large quantity of moisture are lost, and blood osmotic pressure also can correspondingly raise, and high blood oozes thirst center that can Hypothalamic Stimulation, thereby causes symptom thirsty, polydipsia; Due to the relative or absolute shortage of insulin, cause glucose in body not to be utilized, protein and fat consumption increase, thus cause weak, lose weight; For the sugar of recovering damage, maintain body activity, need many feeds; This has just formed typically " three-many-one-little " symptom.The order of severity of the polydipsia of diabetic, polyuria symptom and the state of an illness is proportional.In addition, it should be noted that patient eats manyly, blood glucose is just higher, loses sugar also more in urine, and hunger sensation is also just more severe, has finally caused vicious cycle.Each country almost in the whole world, onset diabetes rate is all rising.This disease is the main cause that causes blind, renal failure, amputation, heart disease and stroke.According to interrelated data, show, China's diabetes city sickness rate higher than rural area 1-4 doubly, produce sugared regional diabetes prevalence higher than 2 times, Fei Chantang district, as can be seen here, people's dietary habit and diabetes have much relations, have a liking for for a long time food sweet food or absorb exquisite starch, higher fatty acid, high heat, high protein, not only easily cause obesity, more make blood glucose be in for a long time higher state, be acknowledged as the independent hazard factor of diabetes.
Along with improving constantly of social development and people's living standard, the sickness rate of countries in the world diabetes (DM) is all rising.Under the organization leadership of diabetology branch of 2007-2008 Nian Chinese Medical Association, the people more than 40,000 in the 20 years old above crowd in domestic 14 cities and towns is investigated, result shows that the prevalence of diabetes is 9.7%, and prediabetes is 15.5%.This result has reflected the prevalence situation of the current diabetes of China more objectively, and this also shows that China is the country that diabetics number is maximum.In recent years, people's rhythm of life rapid growth, life and at heart pressure strengthen, diet fast food gradually in addition, the problems such as hyperlipemia and hyperglycemia are constantly perplexing modern.
Therefore, the health food of auxiliary hyperglycemic function has the wide market demand.
China's Chinese medicine thinks that diabetes mellitus pathogenesis is mainly that the deficiency of YIN is scorching, the deficiency of YIN for this, scorching be mark, the disease being located in the lung stomach kidney three is dirty, can interact, i.e. so-called upper, middle and lower three types of diabetes, corresponding lung stomach kidney three is dirty respectively." but though three types of diabetes one card has dividing of upper, middle and lower, in fact do not get over yin deficiency yang hyperactivity, the solid heat in Tianjin is excessive ".Must be empty as for prolonged illness, impairment of both QI and YIN, yin-yang all loss, even drills that to send out deteriorated case numerous.Knowledge is deaf blind, pulmonary tuberculosis Fu Xian, and edema is pale, yang hyperactivity apoplexy, two is just not normal etc.
It is that primary raw material is made the health food with auxiliary hyperglycemic function that this patent adopts Folium Ginkgo, Thallus Laminariae (Thallus Eckloniae), Fructus Mori, Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, Herba Apocyni veneti on the basis of traditional medicine theory and modern medicine study.
Folium Ginkgo: sweet-bitter flavor, puckery flat, enters the heart, lung, spleen channel.The useful heart is astringed the lung, removing dampness antidiarrheal, the astringing intestine to stop diarrhea of invigorating blood circulation, and cures mainly obstruction of qi in the chest and cardialgia; The phlegmatic cough of breathing with cough; Dysentery.
Thallus Laminariae (Thallus Eckloniae): bitter in the mouth, cold in nature, nontoxic.Return liver, stomach, kidney channel.Hard masses softening and resolving, detumescencing diuresis, relaxing the bowels with lubricant drugs expectorant; Main scrofula, goiter, dysphagic, (Epileptic is ruined) hernia beriberi edema, for goiter, scrofula, painful and swollen testis, phlegm retention edema.
Fructus Mori: sweet in the mouth acid, cold nature, enters the heart, liver, kidney channel.There is nourishing blood to expel wind, tranquillizing and allaying excitement, face skin nourishing intelligence promoting, black hair improving eyesight, can lead to vim and vigour, prevent treating constipation.
Fructus Lycii: sweet in the mouth is flat.Return liver, kidney, lung meridian.Nourishing the liver, nourishing kidney, lung moistening.Conventional it treat hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, quench one's thirst, the disease such as seminal emission.
Flos Chrysanthemi: taste return through: pungent, sweet, bitter, micro-Huang.Return lung, Liver Channel.Dispelling wind and heat pathogens, liver heat removing and eyesight improving.For wind heat exterior syndrome, epidemic febrile disease is from the beginning of, conjunctival congestion and swelling pain, and order is secretly dim-sighted, the vertigo.
Rhizoma Dioscoreae: taste is flat, sweet, nontoxic.Enter lung, spleen, kidney, stomach.Spleen invigorating, thick the intestines and stomach, tonifying the lung, kidney tonifying.Cure mainly diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, seminal emission leukorrhagia, frequent micturition, quenches one's thirst, uterine prolapse.
Radix Salviae Miltiorrhizae: property is bitter, is slightly cold.GUIXIN, Liver Channel.There is promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, the effect of nourishing blood to tranquillize the mind.
Herba Apocyni veneti: nature and flavor are sweet, bitter, cool, return Liver Channel.There is the effects such as suppressing liver-YANG, heat clearing away, diuresis.
This product has tonifying speen and tonifying kidney, drying dampness to eliminate phlegm, and blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN, blood fat reducingization is turbid, the effect of tranquilizing by nourishing the heart.Eight taste Chinese medicines share, can reduce by diet irregular, the harm that life stress is heavy and high fat high-carbonhydrate diet causes human body, simultaneously to visceral dysfunction, the hyperglycemia that the scorching grade of the deficiency of YIN causes all has health-care effect.It is the health food of desirable auxiliary hyperglycemic.
In sum, this product has the health care of auxiliary hyperglycemic.
Summary of the invention
The assembly of auxiliary hyperglycemic capsule and making, composition content (weight) is:
Folium Ginkgo 13-22 part, Thallus Laminariae (Thallus Eckloniae) 15-20 part, Fructus Mori 16-19 part, Fructus Lycii 14-19 part, Flos Chrysanthemi 10-15 part, Rhizoma Dioscoreae 8-12 part, Radix Salviae Miltiorrhizae 3-8 part, Herba Apocyni veneti 4-10 part, through selected, be then processed into capsule by a series of processors by said medicine.
The best content (weight) that forms of the present invention is:
17 parts of Folium Ginkgos, 17 parts of Thallus Laminariae (Thallus Eckloniae)s, 17 parts, Fructus Mori, 17 parts of Fructus Lycii, 12 parts of Flos Chrysanthemis, 10 parts of Rhizoma Dioscoreaes, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Herba Apocyni venetis.
Described a kind of auxiliary hyperglycemic capsule its preparation method is:
1, extract
A, extraction for the first time: Folium Ginkgo 13-22 part, Thallus Laminariae (Thallus Eckloniae) 15-20 part, Fructus Mori 16-19 part, Fructus Lycii 14-19 part, Flos Chrysanthemi 10-15 part, Rhizoma Dioscoreae 8-12 part, Radix Salviae Miltiorrhizae 3-8 part, Herba Apocyni veneti 4-10 part, after cleaning with clear water, be placed in BT-2 rustless steel and extract still, add after 10 times of tap waters, room temperature soaks 1 hour, being heated to 80 ℃ of constant temperature extracts 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use.
B, extraction for the second time: toward extracting the tap water that adds 6 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, pressure filtration, filtrate for later use.
C, extraction for the third time: toward extracting the tap water that adds 3 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, filters filtrate for later use.
2, concentrated
The extracting solution of three extractions is merged, be placed in B-500 type triple effect vacuum high energy evaporation concentrator, decompression (negative 200mmHg), is heated to 80 ℃ and is concentrated into magma.Standby.
3, the preparation of dry powder
In 100,000 grades of dust proof workshops, operate, thick paste is mixed and is placed in drying baker, be heated to 60 ℃, under constant temperature, be dried 4 hours.
4, pelletize, filled capsules
Material by mix homogeneously, is placed in drying equipment, under 70-80 ℃ of condition, is dried 24 hours, is then placed in pulverizer and pulverizes, 80 mesh sieves that sieve, filled capsules.
5, sterilizing
By packaged capsule radiation sterilization.
6, check, finished product, warehouse-in.
Auxiliary hyperglycemic capsule of the present invention has good function of blood sugar reduction, by clinical trial, shows, has good blood sugar lowering ability.
the specific embodiment
Embodiment mono-:
A, extraction for the first time: 17 parts of Folium Ginkgos, 17 parts of Thallus Laminariae (Thallus Eckloniae)s, 17 parts, Fructus Mori, 17 parts of Fructus Lycii, 12 parts of Flos Chrysanthemis, 10 parts of Rhizoma Dioscoreaes, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Herba Apocyni venetis.After cleaning with clear water, be placed in BT-2 rustless steel and extract still, add after 10 times of tap waters, room temperature soaks 1 hour, is heated to 80 constant temperature and extracts 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use.
B, extraction for the second time: toward extracting the tap water that adds 6 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, pressure filtration, filtrate for later use.
C, extraction for the third time: toward extracting the tap water that adds 3 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, filters filtrate for later use.
Three extracting solution are merged, be placed in B-500 type triple effect vacuum high energy evaporation concentrator, decompression (negative 200mmHg), is heated to 80 ℃ and is concentrated into magma.Standby.
A, in 100,000 grades of dust proof workshops, operate, thick paste is mixed and is placed in drying baker, be heated to 60 ℃, under constant temperature dry 4 hours.
B, by the material of mix homogeneously, put in drying equipment, under 70-80 condition dry 4 hours, be then placed in pulverizer and pulverize, the 80 ℃ of mesh sieves that sieve, filled capsules.
C, by packaged capsule radiation sterilization.
D, check, finished product, warehouse-in.
Claims (7)
1. the present invention relates to a kind of assembly and manufacture method of auxiliary hyperglycemic capsule, mainly by Folium Ginkgo, Thallus Laminariae (Thallus Eckloniae), Fructus Mori, Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, formed, it is characterized in that: combination raw materials formula according to quality proportioning is: Folium Ginkgo 13-22 part, Thallus Laminariae (Thallus Eckloniae) 15-20 part, Fructus Mori 16-19 part, Fructus Lycii 14-19 part, Flos Chrysanthemi 10-15 part, Rhizoma Dioscoreae 8-12 part, Radix Salviae Miltiorrhizae 3-8 part, Herba Apocyni veneti 4-10 part; After rationally assembly, through three times, extract, once concentration, pulverizes and sieves after being dried, and is packed into capsule, obtains finished capsule product after sterilizing.
2. according to the assembly of a kind of auxiliary hyperglycemic capsule described in claim 1, it is characterized in that: its best group proportioning according to quality proportioning is: 17 parts of Folium Ginkgos, 17 parts of Thallus Laminariae (Thallus Eckloniae)s, 17 parts, Fructus Mori, 17 parts of Fructus Lycii, 12 parts of Flos Chrysanthemis, 10 parts of Rhizoma Dioscoreaes, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Herba Apocyni venetis.
3. according to the manufacture method of a kind of auxiliary hyperglycemic capsule described in claim 1, it is characterized in that: preparation process is A, extracts for the first time: by Folium Ginkgo 13-22 part, Thallus Laminariae (Thallus Eckloniae) 15-20 part, Fructus Mori 16-19 part, Fructus Lycii 14-19 part, Flos Chrysanthemi 10-15 part, after Rhizoma Dioscoreae 8-12 part, Radix Salviae Miltiorrhizae 3-8 part, Herba Apocyni veneti 4-10 part are cleaned with clear water, be placed in BT-2 rustless steel and extract still, add after 10 times of tap waters, room temperature soaks 1 hour, being heated to 80 ℃ of constant temperature extracts 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use; B, extraction for the second time: toward extracting the tap water that adds 6 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, pressure filtration, filtrate for later use; C, extraction for the third time: toward extracting the tap water that adds 3 times of amounts in still, be heated to 80 ℃ of constant temperature and extract 1 hour, separation and Extraction liquid, filters filtrate for later use.
4. according to the manufacture method of a kind of auxiliary hyperglycemic capsule described in claim 2 and claim 3, it is characterized in that: three extracting solution are merged, be placed in B-500 type triple effect vacuum high energy evaporation concentrator, decompression (negative 200mmHg), be heated to 80 ℃ and be concentrated into magma, standby.
5. according to the manufacture method of a kind of auxiliary hyperglycemic capsule described in claim 3 and claim 4, it is characterized in that: in 100,000 grades of dust proof workshops, operate, thick paste is mixed and is placed in drying baker, be heated to 60 ℃, under constant temperature, be dried 4 hours.
6. according to the manufacture method of a kind of auxiliary hyperglycemic capsule described in claim 1, it is characterized in that: by the material of mix homogeneously, put in drying equipment, under 70-80 ℃ of condition, be dried 4 hours, be then placed in pulverizer and pulverize, 80 mesh sieves that sieve, filled capsules.
7. according to the manufacture method of a kind of auxiliary hyperglycemic capsule described in claim 1, it is characterized in that: by packaged capsule irradiation sterilization, check, finished product, warehouse-in.
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| CN201410382144.8A CN104116885A (en) | 2014-08-06 | 2014-08-06 | Composition for assisting hyperglycemic capsules and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010000070A (en) * | 2000-01-11 | 2001-01-05 | 김찬호 | Agents for diabetes and the manufacturing method thereof |
| CN1931281A (en) * | 2006-09-22 | 2007-03-21 | 海丝克（河南）生物科技有限公司 | Prepn process of capsule for lowering blood lipid, blood sugar and blood pressure |
| CN101062339A (en) * | 2007-05-23 | 2007-10-31 | 魏荣祥 | Medicine for treating diabetes |
-
2014
- 2014-08-06 CN CN201410382144.8A patent/CN104116885A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010000070A (en) * | 2000-01-11 | 2001-01-05 | 김찬호 | Agents for diabetes and the manufacturing method thereof |
| CN1931281A (en) * | 2006-09-22 | 2007-03-21 | 海丝克（河南）生物科技有限公司 | Prepn process of capsule for lowering blood lipid, blood sugar and blood pressure |
| CN101062339A (en) * | 2007-05-23 | 2007-10-31 | 魏荣祥 | Medicine for treating diabetes |
Non-Patent Citations (2)
| Title |
|---|
| 杨安婷等: "中医中药治疗糖尿病60例观察", 《黑龙江医药》 * |
| 河南海丝克生物科技股份有限公司: "银杏桑菊胶囊", 《河南海丝克生物科技股份有限公司官方网站》 * |
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