CN104082537A - Medicine feed additive for promoting growth of weaned piglets and improving immune function - Google Patents
Medicine feed additive for promoting growth of weaned piglets and improving immune function Download PDFInfo
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- CN104082537A CN104082537A CN201410230973.4A CN201410230973A CN104082537A CN 104082537 A CN104082537 A CN 104082537A CN 201410230973 A CN201410230973 A CN 201410230973A CN 104082537 A CN104082537 A CN 104082537A
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Abstract
A provided medicine feed additive for promoting growth of weaned piglets and improving immune function comprises the bulk drugs: radix campanumoea javanicae, semen euryales, garlic, fructus crataegi, acanthopanacis senticosi radix et rhizomaseu caulis, corni fructus, root of przewalsk euonymus, siegesbeckiae Herba, root or herb of rose mallow, achillea alpina, concretio silicea bambusae, aster ageratoides, ootheca mantidis, fructus broussonetiae, dioscoreae spongiosae rhizoma, dendrobii caulis, fructus citri sarcodactylis, radix panacis quinquefolii, fructus litseae, radix curcumae, hippophae fructus, scutellariae radix, coriolus, herb of oblongleaf betony, saururi herba and balanophora involucrate. The medicinal feed additive is capable of promoting metabolism of piglets, promoting growth, improving production performance, improving immunity of piglet bodies and preventing diseases, and is capable of preventing medicine residue in piglet bodies and free of toxic and side effects compared with antibiotics, hormones, chemical synthetic drugs.
Description
Technical field
The present invention relates to traditional Chinese medicine technical field, relate in particular to a kind of for promoting the medicated feed additive of weanling pig growth and raising immunity function.
Background technology
Weanling pig is called again child care pig, refers to that the rear 3-5 of birth weans to the piglet of 10 weeks age grade sections age in week.Under natural conditions, weaned piglet is progressive process, conventionally needs 17 weeks.Under modern raising pattern, for improving sow utilization rate, weaned piglet age in days shifts to an earlier date thereupon, causes piglet that a series of physiological change occurs: diarrhea rate and the death rate raise, premunition declines, poor growth is stagnated.
In modern intensive Swine Production, extensively adopt early weaned technology, piglet leaves after sow, at feeding environment and nutrition flip-flop, again gregarious, set up under the effect of the undesirable elements such as new order of grade, easily occurring stress syndrome taking poor growth and diarrhoea as the early weaning piglet of principal character.Because this disease has higher incidence and the death rate, heavy losses are brought to pig industry.
At present, in animal husbandry is produced, generally adopt and in feed, add antibiotic, hormone, chemical synthetic drugs etc. are prevented and treated livestock and poultry diarrhea, long-term these materials that use, not only easily cause that pathogenic microorganism produces drug resistance, the problems such as animal immunizing power decline and deterioration in quality, these materials are at livestock and poultry meat, milk, residual caused food safety question in egg and edibility internal organ, and in the animal body that causes of antibiotic bacterial drug resistance to the transfer of human disease bacterium, all cause the great attention of national governments, and legislation is made restriction to the use of these materials, therefore becoming, the exploitation of natural resources enjoy popular confidence.
Chinese herbal medicine is to be taken at nature and to have kept its natural structure and bioactive natural drug, its source is abundant, with low cost, and effect extensively, both contained nutriment, and there is again the calmness of calming the nerves, the short digestion of stomach invigorating, vital energy regualting and blood circulation-promoting, support smart help, expelling parasite health care and the effect of preventing and curing diseases.In feed industry, Application and Development Chinese herb feed additive replaces antibiotic and chemical synthetic drug, is extremely important.
Chinese herbal medicine has medicine and nutrition double action concurrently as feed addictive, and both preventable diseases can improve again production performance.From the theory analysis of modern pharmacology and nutrition, Chinese herbal medicine is containing bioactivators such as anti-(pressing down) bacterium composition, alkaloid, polysaccharide, two classes, volatile oil, boots matter and organic acids, also contain amino acid, mineral matter, vitamin, unknown growth regulator and the pigment of some simultaneously, thereby can, by the effect of antibacterial material and immunologic active material, improve the premunition of body.The utilization rate that improves nutriment, has promoted the performance of breeding performonce fo animals.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for promoting weanling pig growth and improving the medicated feed additive of immunity function and the feed that comprises this feed addictive, adopt this medicated feed additive can promote piglet metabolism, promote growth and development, improve production performance, the immunity that improves piglet body, disease preventing and treating, with respect to antibiotic, hormone, chemical synthetic drug, it can prevent at piglet drug disposition residual, has no side effect.
For solving the problems of the technologies described above, the invention provides a kind ofly for promoting weanling pig growth and improving the medicated feed additive of immunity function, its bulk drug comprises Companumoea root, Gorgon fruit, garlic, hawthorn, wilsonii, Fructus Corni, Assorted Chinese Herbal Tea, Herba Siegesbeckiae, Rose Mallow Root, milfoil, Tabasheer, Aster ageratoides, mantis egg-case, Paper mulberry Fruit, continuous Bi moss, the stem of noble dendrobium, Buddha's hand, American Ginseng, piper cubeba, root tuber of aromatic turmeric, sea-buckthorn, the root of large-flowered skullcap, rainbow conk, oblongleaf betony herb or root, saururus chinensis and involucrate balanophora herb.
Wherein, in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 30g～40g, Gorgon fruit 25g～35g, garlic 20g～30g, hawthorn 20g～30g, wilsonii 30g～40g, Fructus Corni 35g～45g, Assorted Chinese Herbal Tea 15g～25g, Herba Siegesbeckiae 10g～20g, Rose Mallow Root 20g～30g, milfoil 20g～30g, Tabasheer 25g～35g, Aster ageratoides 15g～25g, mantis egg-case 20g～30g, Paper mulberry Fruit 20g～30g, continuous Bi moss 10g～20g, stem of noble dendrobium 15g～25g, Buddha's hand 10g～20g, American Ginseng 55g～65g, piper cubeba 15g～25g, root tuber of aromatic turmeric 20g～30g, sea-buckthorn 20g～30g, root of large-flowered skullcap 35g～45g, rainbow conk 15g～25g, oblongleaf betony herb or root 20g～30g, saururus chinensis 15g～25g and involucrate balanophora herb 10g～20g.
Wherein, in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 33g～37g, Gorgon fruit 28g～32g, garlic 23g～27g, hawthorn 23g～27g, wilsonii 33g～37g, Fructus Corni 38g～42g, Assorted Chinese Herbal Tea 18g～22g, Herba Siegesbeckiae 13g～17g, Rose Mallow Root 23g～27g, milfoil 23g～27g, Tabasheer 28g～32g, Aster ageratoides 18g～22g, mantis egg-case 23g～27g, Paper mulberry Fruit 23g～27g, continuous Bi moss 13g～17g, stem of noble dendrobium 18g～22g, Buddha's hand 13g～17g, American Ginseng 58g～62g, piper cubeba 18g～22g, root tuber of aromatic turmeric 23g～27g, sea-buckthorn 23g～27g, root of large-flowered skullcap 38g～42g, rainbow conk 18g～22g, oblongleaf betony herb or root 23g～27g, saururus chinensis 18g～22g and involucrate balanophora herb 13g～17g.
Wherein, in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 35g, Gorgon fruit 30g, garlic 25g, hawthorn 25g, wilsonii 35g, Fructus Corni 40g, Assorted Chinese Herbal Tea 20g, Herba Siegesbeckiae 15g, Rose Mallow Root 25g, milfoil 25g, Tabasheer 30g, Aster ageratoides 20g, mantis egg-case 25g, Paper mulberry Fruit 25g, continuous Bi moss 15g, stem of noble dendrobium 20g, Buddha's hand 15g, American Ginseng 60g, piper cubeba 20g, root tuber of aromatic turmeric 25g, sea-buckthorn 25g, root of large-flowered skullcap 40g, rainbow conk 20g, oblongleaf betony herb or root 25g, saururus chinensis 20g and involucrate balanophora herb 15g.
The present invention also provides the preparation method of said medicine feed addictive, is specially:
Each bulk drug is ground into respectively to powder, sends into stirrer for mixing, obtain mixture, every 100g mixture, adds the water of 500g～600g, boils 3～4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boil 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, and the concentrated aqueous solvent of removing, pulverizes, dry, obtain dry powder, be medicated feed additive.
It is a kind of for promoting the feed of weanling pig growth and raising immunity function that the present invention also provides, and its raw material comprises corn, dregs of beans, salt, fish meal, soya-bean oil, methionine, lysine, tryptophan, VitAVitE, vitamin C and above-mentioned for promoting the medicated feed additive of weanling pig growth and raising immunity function.
Wherein, in described feed, the weight portion of each raw material is respectively corn 280 weight portion～320 weight portions, dregs of beans 140 weight portion～160 weight portions, salt 3 weight portion～5 weight portions, fish meal 30 weight portion～40 weight portions, soya-bean oil 20 weight portion～30 weight portions, methionine 1 weight portion～3 weight portion, lysine 1 weight portion～3 weight portion, tryptophan 1 weight portion～3 weight portion, dehydroretinol weight portion～4 weight portion, vitamin E2 weight portion～4 weight portion, Catergen weight portion～4 weight portion, Chinese traditional medicine feed addictive 55 weight portion～65 weight portions.
Wherein, in described feed, the weight portion of each raw material is respectively corn 300 weight portions, dregs of beans 150 weight portions, salt 4 weight portions, fish meal 35 weight portions, soya-bean oil 25 weight portions, methionine 2 weight portions, lysine 2 weight portions, tryptophan 2 weight portions, 3-Hydroxyretinol weight portion, vitamin E 3 weight portions, vitamin C 3 weight portions, medicated feed additive 60 weight portions.
The present invention also provides the preparation method of above-mentioned feed, comprising:
The first step, prepares described medicated feed additive;
Second step, puts into fodder mixing machine together with the described medicated feed additive that other raw material components in feedstuff and the first step are obtained, and continuous uniform stirred after 1～3 hour, put into pulverizer and pulverized, and obtained feed.
Beneficial effect of the present invention:
The medicated feed additive that the present invention adopts can promote piglet metabolism, promotes growth and development, improves production performance, the immunity that improves piglet body, disease preventing and treating, with respect to antibiotic, hormone, chemical synthetic drug, it can prevent at piglet drug disposition residual, has no side effect.
Detailed description of the invention
The invention provides a kind ofly for promoting weanling pig growth and improving the medicated feed additive of immunity function, its bulk drug comprises Companumoea root, Gorgon fruit, garlic, hawthorn, wilsonii, Fructus Corni, Assorted Chinese Herbal Tea, Herba Siegesbeckiae, Rose Mallow Root, milfoil, Tabasheer, Aster ageratoides, mantis egg-case, Paper mulberry Fruit, continuous Bi moss, the stem of noble dendrobium, Buddha's hand, American Ginseng, piper cubeba, root tuber of aromatic turmeric, sea-buckthorn, the root of large-flowered skullcap, rainbow conk, oblongleaf betony herb or root, saururus chinensis and involucrate balanophora herb.
Described medicated feed additive is further preferably only made up of above-mentioned raw materials medicine.
In described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 30g～40g, Gorgon fruit 25g～35g, garlic 20g～30g, hawthorn 20g～30g, wilsonii 30g～40g, Fructus Corni 35g～45g, Assorted Chinese Herbal Tea 15g～25g, Herba Siegesbeckiae 10g～20g, Rose Mallow Root 20g～30g, milfoil 20g～30g, Tabasheer 25g～35g, Aster ageratoides 15g～25g, mantis egg-case 20g～30g, Paper mulberry Fruit 20g～30g, continuous Bi moss 10g～20g, stem of noble dendrobium 15g～25g, Buddha's hand 10g～20g, American Ginseng 55g～65g, piper cubeba 15g～25g, root tuber of aromatic turmeric 20g～30g, sea-buckthorn 20g～30g, root of large-flowered skullcap 35g～45g, rainbow conk 15g～25g, oblongleaf betony herb or root 20g～30g, saururus chinensis 15g～25g and involucrate balanophora herb 10g～20g.
Further preferably, in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 33g～37g, Gorgon fruit 28g～32g, garlic 23g～27g, hawthorn 23g～27g, wilsonii 33g～37g, Fructus Corni 38g～42g, Assorted Chinese Herbal Tea 18g～22g, Herba Siegesbeckiae 13g～17g, Rose Mallow Root 23g～27g, milfoil 23g～27g, Tabasheer 28g～32g, Aster ageratoides 18g～22g, mantis egg-case 23g～27g, Paper mulberry Fruit 23g～27g, continuous Bi moss 13g～17g, stem of noble dendrobium 18g～22g, Buddha's hand 13g～17g, American Ginseng 58g～62g, piper cubeba 18g～22g, root tuber of aromatic turmeric 23g～27g, sea-buckthorn 23g～27g, root of large-flowered skullcap 38g～42g, rainbow conk 18g～22g, oblongleaf betony herb or root 23g～27g, saururus chinensis 18g～22g and involucrate balanophora herb 13g～17g.
Have most choosing, in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 35g, Gorgon fruit 30g, garlic 25g, hawthorn 25g, wilsonii 35g, Fructus Corni 40g, Assorted Chinese Herbal Tea 20g, Herba Siegesbeckiae 15g, Rose Mallow Root 25g, milfoil 25g, Tabasheer 30g, Aster ageratoides 20g, mantis egg-case 25g, Paper mulberry Fruit 25g, continuous Bi moss 15g, stem of noble dendrobium 20g, Buddha's hand 15g, American Ginseng 60g, piper cubeba 20g, root tuber of aromatic turmeric 25g, sea-buckthorn 25g, root of large-flowered skullcap 40g, rainbow conk 20g, oblongleaf betony herb or root 25g, saururus chinensis 20g and involucrate balanophora herb 15g.
Each bulk drug pharmacology is as follows:
Companumoea root: latin name radix campanumoea javanicae is the root of Campanulaceae leopard platymiscium Campanumoea javanica and leopard, and taste is sweet, property is put down, and returns lung, the spleen channel, has strengthening the spleen and replenishing qi, tonifies the lung to relieve cough, effect of lactogenesis, cures mainly the empty internal injury of labor, and the deficiency of vital energy is weak, palpitaition, hidrosis, splenasthenic diarrhea, leukorrhea, milk rareness, the cards such as insufficiency of the spleen cough.Gorgon fruit:
Garlic: warm in nature, taste is pungent flat; Enter spleen, stomach, lung channel, have in temperature help digestion, effect of row stagnant gas, warming spleen and stomach, long-pending, the removing toxic substances of disappearing, desinsection, cure mainly eating accumulation, coldness and pain in the epigastrium, oedema turgor, have loose bowels, the card such as dysentery, malaria, pertussis, swollen ulcer drug, white bald tinea sore, snake bite and insect sting and hookworm, pinworm.
Hawthorn: taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of faling apart, is mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn is the staple for the treatment of indigestion, hawthorn can increase the secretion of peptic digest enzyme, promotes digestion; Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc. are had to obvious inhibitory action.
Wilsonii: be root, rhizome or the cauline leaf of studies on plants of Acanthopanax Miq. in Araliaceae wilsonii, latin name Acanthopanacis Senticosi Radix et Rhizomaseu Caulis, taste is pungent, bitter, micro-sweet, warm in nature, enter spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is thin and weak, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
Fructus Corni: latin name corni fructus, taste acid, puckery, slightly warm in nature, enter liver, kidney channel, have tonify the liver and kidney, effect that arresting seminal emission, arrest sweating take off admittedly, be mainly used in soreness and weakness of waist and knees, the dizziness and tinnitus of the deficiency of liver-yin and kidney-yin, liver-yang hyperactivity, impotence, essence is closed the cards such as not solid seminal emission, involuntary emission, metrostaxis.
Assorted Chinese Herbal Tea: bitter, pungent, cold nature, has the stasis of blood of dispelling menstruation regulating, and the effect of removing obstruction in channels to relieve pain cures mainly the cards such as irregular menstruation, postpartum abdominal pain, treating swelling and pain by traumatic injury, hemiplegia.
Herba Siegesbeckiae: latin name Siegesbeckiae Herba, taste is cold, pungent, bitter, returns Liver Channel, kidney channel, has wines used as antirheumatic, sharp joint, effect of removing toxic substances, cures mainly the cards such as arthralgia due to wind-dampness, muscles and bones are unable, soreness and weakness of waist and knees, quadriplegia, hemiplegia, the wet sore of rubella.
Rose Mallow Root: taste is sweet, light, property is flat, enters the heart, lung channel, has expelling wind and removing dampness, and clearing heat and detoxicating effect, cures mainly cold, fever, arthralgia due to wind-dampness, dysentery, oedema, leukorrhea, spits blood, and carbuncle is swollen, traumatism and bleeding, venomous snake bite, acute infantile convulsions, lockjaw, asthma, the cards such as stomachache cold after delivery.
Milfoil: taste is pungent; Bitter; Property flat temperature, there is wind-expelling pain-stopping; Effect of promoting blood circulation and detoxication, cures mainly cold, fever; Wind pain; Toothache; Arthralgia due to wind-dampness; Blood stasis is through closing; Belly lump in the abdomen; Traumatic injury; Venomous snake bite; The cards such as carbuncle sore tumefacting virus.
Tabasheer: taste is sweet, cold in nature, there is clear heat and eliminate phlegm, effect of cool heart arresting convulsion, cures mainly pyreticosis coma delirium, and apoplexy phlegm fan in silence, twitch, epilepsy by child convulsion.The cards such as phlegm-heat cough.
Aster ageratoides: bitter, pungent, cool in nature, have clearing heat and detoxicatingly, effect of the cool blood that eliminates the phlegm, cures mainly cold, fever, tonsillitis, bronchitis, hepatitis, enteritis, heat is drenched, the carbuncle serious case of furuncle that swells, the cards such as snake bite and insect sting.
Mantis egg-case: latin name Ootheca Mantidis, become sweet, flat, return liver, kidney, urinary bladder channel, there is kidney tonifying, astringent or styptic treatment for spontaneous sweating, effect of only losing, cure mainly the card such as infantile enuresis, frequent urination at night, seminal emission premature ejaculation, impotence of the insufficiency of the kidney yang, not only help but also inducing astrigency, be tonify the kidney and support yang, the good medicine of controlling nocturnal emission with astringent drugs contracting urine.Emission and spermatorrhea, the enuresis, frequent micturition, impotence due to all kidney yang deficiencies, vital essence mistake are admittedly sterile, all can select the especially suitable enuresis, frequent micturition.
Paper mulberry Fruit: taste is sweet, cold in nature, return liver, kidney channel, there is kidney tonifying clearing liver, effect of improving eyesight diuresis, cures mainly kidney deficiency and liver, soreness and weakness of waist and knees, consumptive disease hectic fever due to yin, has a dizzy spell, the card such as oedema turgor.
Continuous Bi moss: latin name Dioscoreae Spongiosae Rhizoma, property is flat, and bitter, returns kidney, stomach warp, has dampness removing and goes turbidly, and effect of the wind and relieving paralysis of dispelling, for cards such as gonorrhoea gonorrhoea, leukorrhea, damp and hot sore, waist knee numbness pains.
The stem of noble dendrobium: latin name Dendrobii Caulis, cold nature, taste is sweet, returns stomach, kidney channel, has reinforcing stomach reg fluid, and nourishing Yin and clearing heat effect cures mainly the moon and hinders body fluid deficiency, dry polydipsia, food is few retches, abnormal heat after being ill, order is the not clear card that waits secretly.
Buddha's hand: taste is pungent, bitter, warm in nature, returns liver, stomach, lung channel, has soothing the liver promoting the circulation of qi, and in the effect of reducing phlegm, for the distending pain in the chest and hypochondrium of stagnation of QI due to depression of the liver, liver-stomach disharmony, the taste stagnation of the circulation of vital energy, vomits and dislikes food and wait less card.
American Ginseng: sweet, the micro-hardship of taste, cool in nature, the thoughts of returning home, lung, kidney channel, have boosting qi and nourishing yin, and effect of clearing heat and promoting fluid cures mainly the deficiency of vital energy thanks to cloudy, and interior heat, coughs and breathes heavily phlegm blood, and abnormal heat is tired tired, quenches one's thirst, dryness of the mouth and throat.
Piper cubeba: warm in nature, taste is pungent, returns spleen, stomach, kidney, urinary bladder channel, has warming spleen and stomach for dispelling cold, and effect of promoting qi circulation and relieving pain is vomitted for stomach cold contrary, coldness and pain in the epigastrium, cold hernia stomachache, the cards such as stagnancy of cold-damp.
Root tuber of aromatic turmeric: taste is pungent, bitter, cold in nature, returns liver, the heart, lung channel, has regulating qi to disperse stagnation, heart fire-clearing upset-relieving, and effect of normalizing gallbladder to cure jaundice, cures mainly through closing dysmenorrhoea, chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy is gone mad, the red card that waits of jaundice urine.
Sea-buckthorn: latin name Hippophae Fructus, taste acid; Puckery; Warm in nature, have relieving cough and reducing sputum; Stomach strengthening and digestion promoting; Effect of promoting blood circulation to remove blood stasis.Cure mainly coughing with a lot of sputum; Pulmonary abscess; Indigestion; Dyspeptic abdominalgia; Stomachache; Enteritis; Amenorrhoea; Fall and beat the swollen card that waits of the stasis of blood.
The root of large-flowered skullcap: latin name Scutellariae Radix, bitter, cold in nature, enters the heart, lung, stomach, courage, large intestine channel, has heat-clearing and damp-drying drug, and purging intense heat and detonicating is antiabortive, the effect of hemostasis, the diarrhoea, dysentery, jaundice, the heat that are mainly used in due to damp and hot are drenched; Cough with lung heat, thirsty pharyngalgia, also can be used for fetal movement with fever, and hot malicious fire-evil is invaded the swollen card of sore carbuncle poison of excessive skin.
Rainbow conk: latin name Coriolus, taste is sweet, light, and cold nature is returned liver; Spleen; Lung channel, has invigorating spleen to remove dampness; Relieving cough and asthma; Clearing heat and detoxicating; Antineoplastic effect, cures mainly CAH; Cirrhosis; Chronic bronchitis; Infantile spasm bronchitis; Abscess of throat; Kinds of tumors; Rheumatoid arthritis; The cards such as leukaemia.
Oblongleaf betony herb or root: be herb or the root of the oval leaf wood of Labiatae betony, taste is pungent, micro-sweet, warm in nature, has tonifying Qi, effect of hemostasis, cures mainly weakly after being ill, and the deficiency of vital energy is weak, protracted dysentery, the cards such as traumatism and bleeding.
Saururus chinensis: latin name Saururi Herba, taste is sweet, pungent, cold in nature, returns lung, urinary bladder channel, has clearing away heat and promoting diuresis; Effect of removing toxicity for detumescence, cures mainly heat and drenches; Blood drenches; Oedema; Beriberi; Jaundice; Dysentery; Under band; Carbuncle sore tumefacting virus; Eczema; The cards such as snake bite.
Involucrate balanophora herb: bitter, puckery, cold in nature, return lung, stomach, Liver Channel, have and moisten the lung and relieve the cough, promoting the circulation of qi stomach invigorating, clearing heat and promoting diuresis, cooling blood and hemostasis, effect of the puckery essence of kidney tonifying, address cough with lung heat, wrist abdomen pain, jaundice, traumatic injury, spitting of blood, irregular menstruation, uterine bleeding, traumatism and bleeding, giddy, the cards such as seminal emission.
The present invention also provides the preparation method of said medicine feed addictive, is specially:
Each bulk drug is ground into respectively to powder, sends into stirrer for mixing, obtain mixture, every 100g mixture, adds the water of 500g～600g, boils 3～4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boil 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, and the concentrated aqueous solvent of removing, pulverizes, dry, obtain dry powder, be medicated feed additive.
It is a kind of for promoting the feed of weanling pig growth and raising immunity function that the present invention also provides, and its raw material comprises corn, dregs of beans, salt, fish meal, soya-bean oil, methionine, lysine, tryptophan, VitAVitE, vitamin C and above-mentioned for promoting the medicated feed additive of weanling pig growth and raising immunity function.
Further, described feed is only made up of above-mentioned raw materials.
Further, in described feed, the weight portion of each raw material is respectively corn 280 weight portion～320 weight portions, dregs of beans 140 weight portion～160 weight portions, salt 3 weight portion～5 weight portions, fish meal 30 weight portion～40 weight portions, soya-bean oil 20 weight portion～30 weight portions, methionine 1 weight portion～3 weight portion, lysine 1 weight portion～3 weight portion, tryptophan 1 weight portion～3 weight portion, dehydroretinol weight portion～4 weight portion, vitamin E2 weight portion～4 weight portion, Catergen weight portion～4 weight portion, Chinese traditional medicine feed addictive 55 weight portion～65 weight portions.
Further, in described feed, the weight portion of each raw material is respectively corn 300 weight portions, dregs of beans 150 weight portions, salt 4 weight portions, fish meal 35 weight portions, soya-bean oil 25 weight portions, methionine 2 weight portions, lysine 2 weight portions, tryptophan 2 weight portions, 3-Hydroxyretinol weight portion, vitamin E 3 weight portions, vitamin C 3 weight portions, medicated feed additive 60 weight portions.
The present invention also provides the preparation method of above-mentioned feed, comprising:
The first step, prepares described medicated feed additive;
Second step, puts into fodder mixing machine together with the described medicated feed additive that other raw material components in feedstuff and the first step are obtained, and continuous uniform stirred after 1～3 hour, put into pulverizer and pulverized, and obtained feed.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 medicated feed additive 1
By Companumoea root 35g, Gorgon fruit 30g, garlic 25g, hawthorn 25g, wilsonii 35g, Fructus Corni 40g, Assorted Chinese Herbal Tea 20g, Herba Siegesbeckiae 15g, Rose Mallow Root 25g, milfoil 25g, Tabasheer 30g, Aster ageratoides 20g, mantis egg-case 25g, Paper mulberry Fruit 25g, continuous Bi moss 15g, stem of noble dendrobium 20g, Buddha's hand 15g, American Ginseng 60g, piper cubeba 20g, root tuber of aromatic turmeric 25g, sea-buckthorn 25g, root of large-flowered skullcap 40g, rainbow conk 20g, oblongleaf betony herb or root 25g, saururus chinensis 20g and involucrate balanophora herb 15g are ground into respectively powder, send into stirrer for mixing, obtain mixture, every 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boil 2 hours, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, the concentrated aqueous solvent of removing, pulverize, dry, obtain dry powder, be medicated feed additive 1.
Embodiment 2 medicated feed additives 2
By Companumoea root 33g, Gorgon fruit 28g, garlic 23g, hawthorn 23g, wilsonii 33g, Fructus Corni 38
g, Assorted Chinese Herbal Tea 18g, Herba Siegesbeckiae 13g, Rose Mallow Root 23g, milfoil 23g, Tabasheer 28g, Aster ageratoides 18g, mantis egg-case 23g, Paper mulberry Fruit 23g, continuous Bi moss 13g, stem of noble dendrobium 18g, Buddha's hand 13g, American Ginseng 58g, piper cubeba 18g, root tuber of aromatic turmeric 23g, sea-buckthorn 23g, root of large-flowered skullcap 38g, rainbow conk 18g, oblongleaf betony herb or root 23g, saururus chinensis 18g and involucrate balanophora herb 13g are ground into respectively powder, send into stirrer for mixing, obtain mixture, every 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boil 2 hours, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, the concentrated aqueous solvent of removing, pulverize, dry, obtain dry powder, be medicated feed additive 2.
Embodiment 3 medicated feed additives 3
By Companumoea root 37g, Gorgon fruit 32g, garlic 27g, hawthorn 27g, wilsonii 37g, Fructus Corni 42g, Assorted Chinese Herbal Tea 22g, Herba Siegesbeckiae 17g, Rose Mallow Root 27g, milfoil 27g, Tabasheer 32g, Aster ageratoides 22g, mantis egg-case 27g, Paper mulberry Fruit 27g, continuous Bi moss 13g, stem of noble dendrobium 22g, Buddha's hand 17g, American Ginseng 62g, piper cubeba 22g, root tuber of aromatic turmeric 27g, sea-buckthorn 27g, root of large-flowered skullcap 42g, rainbow conk 22g, oblongleaf betony herb or root 27g, saururus chinensis 22g and involucrate balanophora herb 17g are ground into respectively powder, send into stirrer for mixing, obtain mixture, every 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boil 2 hours, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, the concentrated aqueous solvent of removing, pulverize, dry, obtain dry powder, be medicated feed additive 3.
Embodiment 4 toxicology tests
Acute toxicity testing
Select 20 of Kunming mouses, female half and half, body weight (20+2) g, provided by Qingdao City's Experimental Animal Center, medicated feed additive 1 prepared by embodiment 1 is dissolved in distilled water, is prepared into the solution of 1g/ml, gavage mouse, through preliminary experiment, fail to detect the LD of oral administration
50therefore, survey its maximal tolerance dose, with the administration volume of 2.0ml/10g body weight, gavage 2 times/d, interval 6h, gives observation post administration 7d, record animal dead and toxicity symptom, when experiment finishes, by all animals processing, dissect, visually observe each main organs lesion tissue situation, gavage for 2 times after 140g crude drug/kg, animal activity, feed water inlet does not show any abnormalities, and observes 7d animal dead, and gross necropsy has no the obviously abnormal of main organs tissue.
Long term toxicity test
Select 40 male SD rats, weight (180 ± 20) g, provided by Qingdao City's Experimental Animal Center, be divided at random 2 groups, blank group and Chinese drug-treated group, every group 20, blank group gives distilled water, the medicated feed additive 1 that Chinese drug-treated group is prepared embodiment 1 is dissolved in distilled water, be prepared into the solution of 1g/ml, gavage rat, the amount of gavaging is 50g crude drug/kg, on every Mondays to gastric infusion 1 time in morning Saturday, 180d continuously, administration volume is 2mL/100g body weight, observe rat general state every day before administration and during administration, sign, food ration, drinking-water and ight soil situation.When administration 90d, after last administration 24h, each group extracts 6, male and female half and half; When 180d, after last administration 24h, each group extracts 6, male and female half and half; After drug withdrawal, 30d respectively organizes and extracts 6, male and female half and half, anaesthetize with urethane, get blood from abdominal aortic, each group is all killed and gets animal, checks hematology and blood parameters, gets after blood, amass wealth by heavy taxation at once core, the internal organs such as liver,kidney,spleen, lung, adrenal gland, thyroid gland, thymus gland, testis, ovary, uterus, brain, prostate weigh, according to weight calculator official weight coefficient and make pathological examination.
On inspection, during successive administration, activity, body weight, food ration, stool and the hair luster degree no abnormality seen of animal, it is dead that animal has no, naked eyes have no obvious pathology, the inspection of each group rat peripheral hemogram is all in normal range (NR), and the raw tea index of blood is all in normal range (NR), and Chinese drug-treated group Rats Organs and Tissues coefficient does not have significant difference compared with blank group.
Show through toxicology test, Chinese medicine composition feed addictive provided by the invention is nontoxic.
The preparation of embodiment 5 feeds
Medicated feed additive 6kg prepared by corn 30kg, dregs of beans 15kg, salt 0.4kg, fish meal 3.5kg, soya-bean oil 2.5kg, methionine 0.2kg, lysine 0.2kg, tryptophan 0.2kg, vitamin A 0.3kg, vitamin E 0.3kg, vitamin C 0.3kg, embodiment 1 puts into fodder mixing machine together, continuous uniform stirred after 2 hours, put into pulverizer and pulverize, obtain feed 1.
Embodiment 6
Test feed
Feed 1 prepared by effect group feeding embodiment 5; The feed of control group feeding is similar to feed 1, and difference is not add medicated feed additive 1 prepared by embodiment 1, but on the basis of feed 1, adds aureomycin 200g and olaquindox 150g.
Test pig: select parity close, average weight is about 10kg, 210 of the identical towering hybridization of DLY two weanling pigs of kind are as test pig.Be divided at random two groups, control group is fed the basic diet of above-mentioned interpolation aureomycin and olaquindox, feed 1 prepared by effect group feeding embodiment 5.Preliminary trial period 7, is large, experimental period 53, point child care I stage (23 days) and child care II stage (30 days).
Testing index
Production performance: record the situations such as test pig appetite, spirit, ight soil, morbidity every day, weigh and record each group of every daily material consumption.In on-test, child care I stage, child care II stage, while end, weigh on an empty stomach by head, statistics daily gain, material anharmonic ratio.
Immune indexes: the collection of blood sample and processing: when the every one-phase of each processed group finishes, adopt at random 6, took a blood sample the concrete time for 7: 00～10: 00 same day of blood sampling, and every at every turn from vena cava anterior blood sampling 5ml, is placed to and separates out after serum, 3000rpm, centrifugal 15min, draws supernatant, is distributed into inner wrapping,-20 DEG C of preservations, Serum Indexes to be done is measured.
Measure immune indexes and method: immunoglobulin (Ig) (IgG, IgM, IgA) and complement (C
3, C
4) employing end-point method, determining instrument is XD811 semi-automatic biochemical analyzer (upper Hisoon reaches medical apparatus corporation, Ltd and produces), reagent is provided by Zhejiang Province Yilikang Bioisystech Co., Ltd.
Serum interleukin 2 adopts ELISA method, and pig IL-2 kit is by Altru Biomedicines, Inc. of the U.S. and Canadian Fulda Biomedicines, Inc. Joint Production, and Beijing Bang Ding Biomedicines, Inc. provides.
Data processing
Data processing
Measurement data adopts
represent, between group, relatively adopt x
2inspection, all data all adopt the processing of SPSS12.0 statistical software.
Result and discussion
The impact of medicated feed additive on piglet growth performance, the results are shown in Table 1.
The impact of table 1 medicated feed additive on piglet growth performance
As can be seen from Table 1, adopt the pig of the effect group of Chinese medicine feed addictive to show good production performance, can replace to a certain extent antibiotic, chemical synthetic drug, its price of deed rate is higher.
The impact of medicated feed additive on piglet immunological globulin, the results are shown in Table 2.
The impact of table 2 medicated feed additive on piglet immunological globulin
| Project | Group | The child care I stage | The child care II stage |
| IgG(g/L) | Effect group | 4.292±0.315 | 4.976±0.261 |
| ? | Control group | 3.133±0.296 | 3.952±0.179 |
| IgM(g/L) | Effect group | 0.586±0.049 | 0.661±0.053 |
| ? | Control group | 0.492±0.038 | 0.530±0.041 |
| IgA(g/L) | Effect group | 0.736±0.029 | 0.781±0.035 |
| ? | Control group | 0.701±0.025 | 0.722±0.034 |
Immunoglobulin (Ig) be animal be subject in body, to produce after antigenic stimulus can with the interactional class globulin of antigentic specificity.Wherein, IgG has antibacterial, antivirus action, and can neutralize a toxin and make it lose toxicity, conditioning, aggegation and Precipitation Antigen, the most important in humoral immunity; IgM combines with complement after body is subject to pathogen infection, dissolves pathogen; IgA is except performance antibiosis and antiviral functions, the local mucous membrane immunity such as body respiratory tract, alimentary canal are also played to important " barrier " effect, by table 2, we can find out, IgG, the IgM of the piglet serum of effect group and IgA raising amount will be apparently higher than control groups.
Medicated premix is to piglet SC C
3, C
4impact, the results are shown in Table 3.
Table 3 medicated premix is to piglet SC C
3, C
4impact
| Project | Group | The child care I stage | The child care II stage |
| C 3(g/L) | Effect group | 0.437±0.029 | 0.551±0.039 |
| ? | Control group | 0.368±0.021 | 0.423±0.031 |
| C 34(g/L) | Effect group | 0.069±0.012 | 0.093±0.013 |
| ? | Control group | 0.041±0.016 | 0.058±0.009 |
Complement is the chief component of body specific immunity, participates in immune response and the homeostatic function of body protective, assists antibody and phagocyte pathogenic microbe killing; improve the non-specific anti-infectious function of body; by table 3, we can find out, the C of the piglet serum of effect group
3, C
4content raising amount will be apparently higher than control group.
The impact of medicated premix on interleukin 2, the results are shown in Table 4
The affect unit of table 4 medicated premix on interleukin 2: pg/ml
| Group | The child care I stage | The child care II stage |
| Effect group | 35.367±0.813 | 38.267±0.730 |
| Control group | 32.173±0.639 | 33.517±0.706 |
Interleukin 2 is the factor that is produced and promoted T lymphocyte growth by the T lymphocyte activating, and it is the key link that ensures the normal immunologic function of body, can, by impelling clone's property propagation of a certain specific T cell colony, pass through T
hthe raising of cell number and function strengthens overall function.Mammal research shows, interleukin 2 promotes a large amount of propagation of thymus gland and secretion, promote the performance of B cell proliferation and expression and function, utilize activity of interleukin-2 to detect to reflect lymphocytic function, the particularly function of T cell, increasingly for the research of immunologic function, by table 4, we can find out, the IL-2 Content raising amount of the piglet serum of effect group will be apparently higher than control group.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing amendment, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the restriction of the present invention being made to other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (5)
1. for promoting a medicated feed additive for weanling pig growth and raising immunity function, it is characterized in that: bulk drug comprises Companumoea root, Gorgon fruit, garlic, hawthorn, wilsonii, Fructus Corni, Assorted Chinese Herbal Tea, Herba Siegesbeckiae, Rose Mallow Root, milfoil, Tabasheer, Aster ageratoides, mantis egg-case, Paper mulberry Fruit, continuous Bi moss, the stem of noble dendrobium, Buddha's hand, American Ginseng, piper cubeba, root tuber of aromatic turmeric, sea-buckthorn, the root of large-flowered skullcap, rainbow conk, oblongleaf betony herb or root, saururus chinensis and involucrate balanophora herb.
2. medicated feed additive as claimed in claim 1, it is characterized in that: in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 30g～40g, Gorgon fruit 25g～35g, garlic 20g～30g, hawthorn 20g～30g, wilsonii 30g～40g, Fructus Corni 35g～45g, Assorted Chinese Herbal Tea 15g～25g, Herba Siegesbeckiae 10g～20g, Rose Mallow Root 20g～30g, milfoil 20g～30g, Tabasheer 25g～35g, Aster ageratoides 15g～25g, mantis egg-case 20g～30g, Paper mulberry Fruit 20g～30g, continuous Bi moss 10g～20g, stem of noble dendrobium 15g～25g, Buddha's hand 10g～20g, American Ginseng 55g～65g, piper cubeba 15g～25g, root tuber of aromatic turmeric 20g～30g, sea-buckthorn 20g～30g, root of large-flowered skullcap 35g～45g, rainbow conk 15g～25g, oblongleaf betony herb or root 20g～30g, saururus chinensis 15g～25g and involucrate balanophora herb 10g～20g.
3. medicated feed additive as claimed in claim 1 or 2, it is characterized in that: in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 33g～37g, Gorgon fruit 28g～32g, garlic 23g～27g, hawthorn 23g～27g, wilsonii 33g～37g, Fructus Corni 38g～42g, Assorted Chinese Herbal Tea 18g～22g, Herba Siegesbeckiae 13g～17g, Rose Mallow Root 23g～27g, milfoil 23g～27g, Tabasheer 28g～32g, Aster ageratoides 18g～22g, mantis egg-case 23g～27g, Paper mulberry Fruit 23g～27g, continuous Bi moss 13g～17g, stem of noble dendrobium 18g～22g, Buddha's hand 13g～17g, American Ginseng 58g～62g, piper cubeba 18g～22g, root tuber of aromatic turmeric 23g～27g, sea-buckthorn 23g～27g, root of large-flowered skullcap 38g～42g, rainbow conk 18g～22g, oblongleaf betony herb or root 23g～27g, saururus chinensis 18g～22g and involucrate balanophora herb 13g～17g.
4. the medicated feed additive as described in claims 1 to 3, it is characterized in that: in described medicated feed additive, the weight of each bulk drug is respectively Companumoea root 35g, Gorgon fruit 30g, garlic 25g, hawthorn 25g, wilsonii 35g, Fructus Corni 40g, Assorted Chinese Herbal Tea 20g, Herba Siegesbeckiae 15g, Rose Mallow Root 25g, milfoil 25g, Tabasheer 30g, Aster ageratoides 20g, mantis egg-case 25g, Paper mulberry Fruit 25g, continuous Bi moss 15g, stem of noble dendrobium 20g, Buddha's hand 15g, American Ginseng 60g, piper cubeba 20g, root tuber of aromatic turmeric 25g, sea-buckthorn 25g, root of large-flowered skullcap 40g, rainbow conk 20g, oblongleaf betony herb or root 25g, saururus chinensis 20g and involucrate balanophora herb 15g.
5. the preparation method of medicated feed additive described in claim 1 to 4, is characterized in that:
Each bulk drug is ground into respectively to powder, sends into stirrer for mixing, obtain mixture, every 100g mixture, adds the water of 500g～600g, boils 3～4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boil 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, and the concentrated aqueous solvent of removing, pulverizes, dry, obtain dry powder, be medicated feed additive.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106071229A (en) * | 2016-06-21 | 2016-11-09 | 山东新希望六和集团有限公司 | A kind of winter raises pigs and uses feed additive |
| CN114343056A (en) * | 2022-01-04 | 2022-04-15 | 江西省农业科学院畜牧兽医研究所 | Omics type Chinese herbal medicine functional substitution antibody composition for weaned piglets and preparation method and application thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791046A (en) * | 2010-04-06 | 2010-08-04 | 许雪姣 | Compound feed for piglets |
| CN102239972A (en) * | 2011-08-11 | 2011-11-16 | 上海交通大学 | Traditional Chinese medicine feed additive used to improve immunity and resist parasitic infection of weaned piglets and preparation and use method thereof |
| CN103120726A (en) * | 2013-02-28 | 2013-05-29 | 河南科技大学 | Traditional Chinese medicine composition for improving weaned pig growth performance and preparation method thereof |
| CN103141711A (en) * | 2013-04-02 | 2013-06-12 | 山东新希望六和集团有限公司 | Feed for improving immunity of piglets and preparation method of feed |
| CN103355556A (en) * | 2013-08-05 | 2013-10-23 | 山东新希望六和集团有限公司 | Corn type mixed feed for weaned pig and preparation method thereof |
| CN103734547A (en) * | 2014-01-27 | 2014-04-23 | 山东新希望六和集团有限公司 | Pig feed for promoting growth of piglets and Chinese medicine additive and preparing method of pig feed and Chinese medicine additive |
| CN103750037A (en) * | 2014-01-10 | 2014-04-30 | 重庆木犴生猪养殖有限公司 | Piglet feed additive and preparation method thereof |
-
2014
- 2014-05-28 CN CN201410230973.4A patent/CN104082537B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791046A (en) * | 2010-04-06 | 2010-08-04 | 许雪姣 | Compound feed for piglets |
| CN102239972A (en) * | 2011-08-11 | 2011-11-16 | 上海交通大学 | Traditional Chinese medicine feed additive used to improve immunity and resist parasitic infection of weaned piglets and preparation and use method thereof |
| CN103120726A (en) * | 2013-02-28 | 2013-05-29 | 河南科技大学 | Traditional Chinese medicine composition for improving weaned pig growth performance and preparation method thereof |
| CN103141711A (en) * | 2013-04-02 | 2013-06-12 | 山东新希望六和集团有限公司 | Feed for improving immunity of piglets and preparation method of feed |
| CN103355556A (en) * | 2013-08-05 | 2013-10-23 | 山东新希望六和集团有限公司 | Corn type mixed feed for weaned pig and preparation method thereof |
| CN103750037A (en) * | 2014-01-10 | 2014-04-30 | 重庆木犴生猪养殖有限公司 | Piglet feed additive and preparation method thereof |
| CN103734547A (en) * | 2014-01-27 | 2014-04-23 | 山东新希望六和集团有限公司 | Pig feed for promoting growth of piglets and Chinese medicine additive and preparing method of pig feed and Chinese medicine additive |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106071229A (en) * | 2016-06-21 | 2016-11-09 | 山东新希望六和集团有限公司 | A kind of winter raises pigs and uses feed additive |
| CN114343056A (en) * | 2022-01-04 | 2022-04-15 | 江西省农业科学院畜牧兽医研究所 | Omics type Chinese herbal medicine functional substitution antibody composition for weaned piglets and preparation method and application thereof |
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Denomination of invention: Medicine feed additive for promoting growth of weaned piglets and improving immune function Effective date of registration: 20200115 Granted publication date: 20160608 Pledgee: Bank of Communications Ltd. Jiangxi branch Pledgor: JIANGXI GAOSHENG ANIMAL HEALTH CARE PRODUCTS LTD. Registration number: Y2020360000004 |
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Date of cancellation: 20230802 Granted publication date: 20160608 Pledgee: Bank of Communications Ltd. Jiangxi branch Pledgor: JIANGXI GAOSHENG ANIMAL HEALTH CARE PRODUCTS LTD. Registration number: Y2020360000004 |
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