CN104069409A - Pharmaceutical composition for relieving cough and asthma - Google Patents

Pharmaceutical composition for relieving cough and asthma Download PDF

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Publication number
CN104069409A
CN104069409A CN201410281608.6A CN201410281608A CN104069409A CN 104069409 A CN104069409 A CN 104069409A CN 201410281608 A CN201410281608 A CN 201410281608A CN 104069409 A CN104069409 A CN 104069409A
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parts
pharmaceutical composition
asthma
folium
fructus
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CN201410281608.6A
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蔡卓慧
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Abstract

The invention discloses a pharmaceutical composition for relieving cough and asthma. The pharmaceutical composition consists of the following materials: 6-18 parts of semen armeniacae amarae, 6-18 parts of perilla fruits, 15-28 parts of radix stemonae, 15-28 parts of tussilago farfara, 10-24 parts of aster, 10-24 parts of birthwort, 10-24 parts of loquat leaves, 6-18 parts of white mulberry root-barks, 8-16 parts of semen lepidii, 2-10 parts of ginkgoes, 2-10 parts of ginkgoes, 2-10 parts of ardisia japonica, 2-10 parts of flos daturae, 8-16 parts of physochlaina macrophylla, 15-28 parts of folium rhododendri daurici, 22-38 parts of thorny elaeagnus leaves, and 10-24 parts of momordica grosvenori. A dosage form of the pharmaceutical composition can be medically acceptable dosage forms such as capsule, tablet, spray and decoction, wherein the preparation method for the dosage forms and dosage amount of auxiliary materials are carried out according to the normal process. The pharmaceutical composition disclosed by the invention overcomes the defects of the existing drugs for relieving cough and asthma; the pharmaceutical composition with good effects for treating bronchitis and asthmatic bronchitis is provided, curative effect temperature and toxic and side effect are relatively lower.

Description

A kind of pharmaceutical composition of relieving cough and asthma
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of pharmaceutical composition of relieving cough and asthma.
Background technology
Bronchitis, asthmatic bronchitis are a kind of commonly encountered diseases, frequently-occurring disease.The common sympton of asthmatic patient be paroxysmally pant, the symptom such as out of breath, uncomfortable in chest or cough, small number of patients also may be taking chest pain as main manifestations.The risk factor of asthma comprises host factor (inherited genetic factors) and two aspects of environmental factors.Inherited genetic factors can embody with it a lot of patients, in the middle of most patients' relatives (have relationship by blood, nearly three generations people), asthma (recurrent cough, pant) or other anaphylactic diseases (allergic rhinitis, atopic dermatitis) medical history can be traced back to.Most of asthmatic patients belong to allergic constitution, itself may be with allergic rhinitis and atopic dermatitis, or allergen (acarid, pollen, house pet, mycete etc.) to common air-borne transmission, some food (nut, milk, Semen arachidis hypogaeae, seafood etc.), drug allergy etc.
In the recent decade, the U.S., Britain, Australia, the national asthma prevalence such as New Zealand and mortality rate are on the rise, approximately there are 100,000,000 asthmatic patients in the whole world, become the main chronic disease of one of serious threat public health, the prevalence of China's asthma is about 1%, and child Ke Da 3% approximately has 1,000 ten thousand above asthmatic patients according to the measuring and calculating whole nation.Asthma is to affect the able-bodied important diseases of people, treatment not in time, lack of standardization, asthma may be fatal, therefore treats in time asthma extremely important.Of the prior art, medical circle is mainly with western medicine, but chemicals mostly has some side effect.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition of relieving cough and asthma, this medicine has effect of relieving cough and asthma, can be good at treating asthma, and without recurrence effect.
The technical scheme of the pharmaceutical composition of a kind of relieving cough and asthma of the present invention is achieved in that a kind of pharmaceutical composition of relieving cough and asthma, in weight portion, its component is: 6~18 parts of Semen Armeniacae Amarums, 6~18 parts of Fructus Perillaes, 15~28 parts of the Radixs Stemonae, 15~28 parts of Flos Farfaraees, 10~24 parts of Radix Asteriss, 10~24 parts of Fructus Aristolochiaes, 10~24 parts of Folium Eriobotryaes, 6~18 parts of Cortex Mori, 8~16 parts of careless Li, 2~10 parts of Semen Ginkgoes, 2~10 parts of Herba Ardisiae Japonicaes, 2~10 parts of Flos Daturaes, 8~16 parts of Radix Physochlainae, 15~28 parts of Folium Rhododendri Daurici, 22~38 parts of Folium Elaeagnves, 10~24 parts of Fructus Momordicaes.
And the weight portion of described pharmaceutical composition is preferably: 8~12 parts of Semen Armeniacae Amarums, 8~12 parts of Fructus Perillaes, 18~24 parts of the Radixs Stemonae, 18~24 parts of Flos Farfaraees, 12~18 parts of Radix Asteriss, 12~18 parts of Fructus Aristolochiaes, 12~18 parts of Folium Eriobotryaes, 8~12 parts of Cortex Mori, 10~14 parts of careless Li, 4~8 parts of Semen Ginkgoes, 4~8 parts of Herba Ardisiae Japonicaes, 4~8 parts of Flos Daturaes, 10~14 parts of Radix Physochlainae, 18~24 parts of Folium Rhododendri Daurici, 26~32 parts of Folium Elaeagnves, 12~18 parts of Fructus Momordicaes.
Optimum weight part of described pharmaceutical composition is: 9 parts of Semen Armeniacae Amarums, 9 parts of Fructus Perillaes, 20 parts of the Radixs Stemonae, 20 parts of Flos Farfaraees, 15 parts of Radix Asteriss, 15 parts of Fructus Aristolochiaes, 15 parts of Folium Eriobotryaes, 9 parts of Cortex Mori, 12 parts of careless Li, 6 parts of Semen Ginkgoes, 6 parts of Herba Ardisiae Japonicaes, 6 parts of Flos Daturaes, 12 parts of Radix Physochlainae, 20 parts of Folium Rhododendri Daurici, 30 parts of Folium Elaeagnves, 15 parts of Fructus Momordicaes.
The dosage form of pharmaceutical composition of the present invention can be the medically acceptable dosage forms such as capsule, tablet, spray, decoction, and their preparation method, supplementary product consumption are undertaken by existing common process.
The present invention also comprises the application of aforementioned pharmaceutical compositions in the medicine of preparing relieving cough and asthma.
In pharmaceutical composition prescription of the present invention:
Semen Armeniacae Amarum: slightly poisonous, respectful falling has a surname concurrently among waste gas and send out the merit of lung qi and reach relieving cough and asthma, and relieving cough and asthma power is strong, can plant cough with asthma in Zhiduo County with card compatibility.
Fructus Perillae: relatively lowering the adverse-rising QI to resolve phlegm, relieving cough and asthma.
The Radix Stemonae: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.
Flos Farfarae: nourishing the lung to keep the adverse QI downward, antitussive reduces phlegm; Control cough with dyspnea and pant, sore throat.
Radix Asteris: nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.Main cough; Deficiency of the lung chronic cough; Consumptive lung disease lung abscess; Cough vomiting bloody pus; Dysuria.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.
Fructus Aristolochiae: lung heat clearing sending down the abnormal ascending QI, relieving cough and asthma, the bowel relieving hemorrhoid that disappear; For dyspnea and cough due to lung-heat, sputum mixed with blood, the hot hemorrhoidal bleeding of intestinal, swelling and pain of hemorrhoid.
Folium Eriobotryae: cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastropyretic vomiting, hiccup.
Cortex Mori: Gan Han, enters lung meridian.There is inducing diuresis to remove edema, repair effect of cicatrix.
Grass Li: the specially soft antiasthmatic-antitussive of water in eliminating the pathogens from the lung, doublely rush down stool, cure mainly accumulation and obstruction of sputum, must not breath with cough and equal excess syndrome sleeping, difficulty in urination and defecation, and the power of inducing diuresis to remove edema is stronger.
Semen Ginkgo: relatively astringing lung-QI and dissipating phlegm Dingchuan, again can astringent therapy leukorrhagia stopping, reducing urination.
Herba Ardisiae Japonicae: expelling phlegm for arresting cough effect is more remarkable, again can eliminating damp-heat, invigorates blood circulation and controls silt.
Flos Daturae: being anesthesia antitussive and antiasthmatic medicine, and being good at narcotic analgesic, is the medicine of Chinese drug anesthesia, and can relieving convulsion.
Radix Physochlainae: relieving cough and asthma, again can warming the lung to eliminate phlegm.
Folium Rhododendri Daurici: relatively expelling phlegm for arresting cough.
Folium Elaeagni: can stop blooding again, removing toxic substances.
Fructus Momordicae: relatively removing heat from the lung and relieving sorethroat, preventing phlegm from forming and stopping coughing, and can loosening bowel to relieve constipation.
Semen Armeniacae Amarum in the present invention formula, Fructus Perillae can sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation; The Radix Stemonae, Flos Farfarae, Radix Asteris are gentle not dry, are longer than nourishing the lung to keep the adverse QI downward cough-relieving, for cough, and Exogenous and internal injuries, cold and heat and asthenia and sthenia, all can use by compatibility; Fructus Aristolochiae, the Folium Eriobotryae lung that can disappear reduces phlegm, relieving cough and asthma; Cortex Mori, careless Li can eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema; Semen Ginkgo, Herba Ardisiae Japonicae, Flos Daturae, Radix Physochlainae, Folium Rhododendri Daurici, Folium Elaeagni, Fructus Momordicae can relieving cough and asthma formula combination, can effectively treat asthma, cough, bronchitis.The present invention fills a prescription proves effective percentage 100% through clinical practice, cure rate 85%, this pharmaceutical composition is that inventor is according to theory of Chinese medical science and sum up the technical scheme of science practicality out in long-term practice in conjunction with secret prescription handed down in the family from generation to generation, having followed the principle of strengthening vital QI to eliminate pathogenic factors, treating both the principal and secondary aspects of a disease, is collection antiinflammatory, heat-clearing and toxic substances removing, spleen reinforcing kidney, sharp lung qi, pharmaceutical composition that relieving cough and asthma is integrated, asthma is had to good therapeutical effect, rapid-action, without recurrence, stable curative effect; The present invention is pure Chinese medicinal preparation, determined curative effect, and toxic and side effects is relatively little, particularly has significant curative effect for senile, intractable cough illness, can remove to greatest extent the misery that cough illness is brought to them.
The present invention takes this medicine through 30 patients, and its clinical statistics data and criterion of therapeutical effect are: symptomatology disappears for curing, and cough and asthma symptom alleviate as effectively.Medication process is taken 3 times every day, each serving with 80~120mL, continuous 15 days.Result has 26 patients to cure, and 4 patients are effective, and total effective rate is 100%.
Detailed description of the invention
Embodiment 1
Semen Armeniacae Amarum 60g, Fructus Perillae 60g, Radix Stemonae 150g, Flos Farfarae 150g, Radix Asteris 100g, Fructus Aristolochiae 100g, Folium Eriobotryae 100g, Cortex Mori 60g, careless Li 80g, Semen Ginkgo 20g, Herba Ardisiae Japonicae 20g, Flos Daturae 20g, Radix Physochlainae 80g, Folium Rhododendri Daurici 150g, Folium Elaeagni 220g, Fructus Momordicae 100g.
Preparation method: take above each raw material by proportional quantity, add 4 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 20 minutes, then uses slow fire boiling 20 minutes, filters, and decoction liquor is poured in container for the first time; Add water for the second time 2 times and measure, intense fire decocts boiling 20 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time; Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, technique is made decoction routinely.
Embodiment 2
Semen Armeniacae Amarum 180g, Fructus Perillae 180g, Radix Stemonae 280g, Flos Farfarae 280g, Radix Asteris 240g, Fructus Aristolochiae 240g, Folium Eriobotryae 240g, Cortex Mori 180g, careless Li 160g, Semen Ginkgo 100g, Herba Ardisiae Japonicae 100g, Flos Daturae 100g, Radix Physochlainae 160g, Folium Rhododendri Daurici 280g, Folium Elaeagni 380g, Fructus Momordicae 240g.
Preparation method: take above each raw material by proportional quantity, add 5 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 25 minutes, then uses slow fire boiling 30 minutes, filters, and decoction liquor is poured in container for the first time; Add water for the second time 3 times and measure, intense fire decocts boiling 25 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time; Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, filtrate is concentrated into relative density be 1.30 extractum of (75 DEG C time survey), adds the cane sugar powder of conventional amount used, mixes granulation.
Embodiment 3
Semen Armeniacae Amarum 80g, Fructus Perillae 80g, Radix Stemonae 180g, Flos Farfarae 180g, Radix Asteris 120g, Fructus Aristolochiae 120g, Folium Eriobotryae 120g, Cortex Mori 80g, careless Li 100g, Semen Ginkgo 40g, Herba Ardisiae Japonicae 40g, Flos Daturae 40g, Radix Physochlainae 100g, Folium Rhododendri Daurici 180g, Folium Elaeagni 260g, Fructus Momordicae 120g.
Preparation method: take above each raw material by proportional quantity, dry, pulverize, cross 80 mesh sieves, soak 2 months with 60 degree rice wine 50kg, filter and remove residue, gets supernatant and adds the penetrating agent of conventional amount used and antiseptic to shake even spray.
Embodiment 4
Semen Armeniacae Amarum 120g, Fructus Perillae 120g, Radix Stemonae 240g, Flos Farfarae 240g, Radix Asteris 180g, Fructus Aristolochiae 180g, Folium Eriobotryae 180g, Cortex Mori 120g, careless Li 140g, Semen Ginkgo 80g, Herba Ardisiae Japonicae 80g, Flos Daturae 80g, Radix Physochlainae 140g, Folium Rhododendri Daurici 240g, Folium Elaeagni 320g, Fructus Momordicae 180g.
Preparation method: take above each raw material by proportional quantity, add 5 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 25 minutes, then uses slow fire boiling 30 minutes, filters, and decoction liquor is poured in container for the first time; Add water for the second time 3 times and measure, intense fire decocts boiling 25 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time; Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, filtrate is concentrated into relative density be 1.30 extractum of (75 DEG C time survey), adds the magnesium stearate adjuvant of conventional amount used, and technique becomes tablet routinely, specification 0.5g/ sheet.
Embodiment 5
Semen Armeniacae Amarum 90g, Fructus Perillae 90g, Radix Stemonae 200g, Flos Farfarae 200g, Radix Asteris 150g, Fructus Aristolochiae 150g, Folium Eriobotryae 150g, Cortex Mori 90g, careless Li 120g, Semen Ginkgo 60g, Herba Ardisiae Japonicae 60g, Flos Daturae 60g, Radix Physochlainae 120g, Folium Rhododendri Daurici 200g, Folium Elaeagni 300g, Fructus Momordicae 150g.
Preparation method: take above each raw material by proportional quantity, add 5 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 25 minutes, then uses slow fire boiling 30 minutes, filters, and decoction liquor is poured in container for the first time; Add water for the second time 3 times and measure, intense fire decocts boiling 25 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time; Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, filtrate is concentrated into relative density be 1.30 extractum of (75 DEG C time survey), adds the dextrin adjuvant of conventional amount used, and technique routinely, makes capsule, 0.5g/ grain.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.

Claims (4)

1. the pharmaceutical composition of a relieving cough and asthma, it is characterized in that, in weight portion, its component is: 6~18 parts of Semen Armeniacae Amarums, 6~18 parts of Fructus Perillaes, 15~28 parts of the Radixs Stemonae, 15~28 parts of Flos Farfaraees, 10~24 parts of Radix Asteriss, 10~24 parts of Fructus Aristolochiaes, 10~24 parts of Folium Eriobotryaes, 6~18 parts of Cortex Mori, 8~16 parts of careless Li, 2~10 parts of Semen Ginkgoes, 2~10 parts of Herba Ardisiae Japonicaes, 2~10 parts of Flos Daturaes, 8~16 parts of Radix Physochlainae, 15~28 parts of Folium Rhododendri Daurici, 22~38 parts of Folium Elaeagnves, 10~24 parts of Fructus Momordicaes.
2. pharmaceutical composition as claimed in claim 1, it is characterized in that, the weight portion of described component is: 8~12 parts of Semen Armeniacae Amarums, 8~12 parts of Fructus Perillaes, 18~24 parts of the Radixs Stemonae, 18~24 parts of Flos Farfaraees, 12~18 parts of Radix Asteriss, 12~18 parts of Fructus Aristolochiaes, 12~18 parts of Folium Eriobotryaes, 8~12 parts of Cortex Mori, 10~14 parts of careless Li, 4~8 parts of Semen Ginkgoes, 4~8 parts of Herba Ardisiae Japonicaes, 4~8 parts of Flos Daturaes, 10~14 parts of Radix Physochlainae, 18~24 parts of Folium Rhododendri Daurici, 26~32 parts of Folium Elaeagnves, 12~18 parts of Fructus Momordicaes.
3. pharmaceutical composition as claimed in claim 2, it is characterized in that, the weight portion of described component is: 9 parts of Semen Armeniacae Amarums, 9 parts of Fructus Perillaes, 20 parts of the Radixs Stemonae, 20 parts of Flos Farfaraees, 15 parts of Radix Asteriss, 15 parts of Fructus Aristolochiaes, 15 parts of Folium Eriobotryaes, 9 parts of Cortex Mori, 12 parts of careless Li, 6 parts of Semen Ginkgoes, 6 parts of Herba Ardisiae Japonicaes, 6 parts of Flos Daturaes, 12 parts of Radix Physochlainae, 20 parts of Folium Rhododendri Daurici, 30 parts of Folium Elaeagnves, 15 parts of Fructus Momordicaes.
4. the application of the pharmaceutical composition described in any one in the medicine of preparing relieving cough and asthma in claim 1~3.
CN201410281608.6A 2014-06-23 2014-06-23 Pharmaceutical composition for relieving cough and asthma Pending CN104069409A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758761A (en) * 2015-03-26 2015-07-08 王军红 Traditional Chinese medicine composition for treating bronchial asthma
CN105125837A (en) * 2015-09-29 2015-12-09 路宏燕 Spray relieving asthma of bronchial asthma attack and preparation method thereof
CN105255656A (en) * 2015-11-18 2016-01-20 蒋丽红 Wine yeast and preparation method thereof
CN105816766A (en) * 2016-04-20 2016-08-03 袁贯丽 Traditional Chinese medicine composition for relieving cough and asthma and preparation method of traditional Chinese medicine composition
CN108967594A (en) * 2018-08-31 2018-12-11 安徽绿月茶业有限公司 A kind of relieving cough and asthma green tea tea bag and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758761A (en) * 2015-03-26 2015-07-08 王军红 Traditional Chinese medicine composition for treating bronchial asthma
CN105125837A (en) * 2015-09-29 2015-12-09 路宏燕 Spray relieving asthma of bronchial asthma attack and preparation method thereof
CN105255656A (en) * 2015-11-18 2016-01-20 蒋丽红 Wine yeast and preparation method thereof
CN105816766A (en) * 2016-04-20 2016-08-03 袁贯丽 Traditional Chinese medicine composition for relieving cough and asthma and preparation method of traditional Chinese medicine composition
CN108967594A (en) * 2018-08-31 2018-12-11 安徽绿月茶业有限公司 A kind of relieving cough and asthma green tea tea bag and preparation method thereof

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