CN104069240B - The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy - Google Patents
The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy Download PDFInfo
- Publication number
- CN104069240B CN104069240B CN201410286973.6A CN201410286973A CN104069240B CN 104069240 B CN104069240 B CN 104069240B CN 201410286973 A CN201410286973 A CN 201410286973A CN 104069240 B CN104069240 B CN 104069240B
- Authority
- CN
- China
- Prior art keywords
- herb
- chinese medical
- patient
- chemotherapy
- oral cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses the Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy. Chemotherapeutics suppresses hemopoietic function of bone marrow, and leucocyte is declined, and patient's resistance reduces, add gastrointestinal reaction, salivary secretion reduces, and oral cavity self-cleaning action weakens, bacterium in oral cavity rapidly breeding, fermentation, acid production strengthen, cause oral mucosa impaired and form canker sore. The present invention selects to have Chinese medicine Brittle Falsepimpernel Herb, smallleaf desmodium herb, pilosella-leaved drymoglossum herb, star, Thymifoious Euphorbia Herb, the catchweed bedstraw herb of heat-clearing and damp-drying drug, removing toxic substances, makes GARG, and through clinical testing, the treatment group ulcer incidence of disease is starkly lower than control group, and treatment cost is low, and side effect is little.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to due to a kind of Prophylactic chemotherapyThe Chinese medical collutory of stomatitis.
Background technology
One of modal complication when stomatitis is malignant tumor patient chemotherapy, not onlyAffect patient's feed, even hinder next step treatment, as infect, also can drawPlay the serious consequences such as septicemia. I find through clinical observation for many years, in utilizationDue to medicine GARG Prophylactic chemotherapy, stomatitis has good curative effect.
Summary of the invention
The object of this invention is to provide the Chinese medicine of stomatitis due to a kind of Prophylactic chemotherapy containing garglingLiquid. Chemotherapeutics suppresses hemopoietic function of bone marrow, leucocyte is declined, patient's resistanceReduce, add gastrointestinal reaction, patient's feed, drinking-water reduce, and salivary secretion reduces,Oral cavity self-cleaning action weakens, and bacterium is breeding rapidly in oral cavity, fermentation, acid productionStrengthen, intraoral microenvironment changes, and has weakened the defense function in oral cavity, mouthfulChamber pH value reduces and causes oral mucosa impaired and form canker sore. The traditional Chinese medical science is thought disputeRaw sore is that heat is taken advantage of heart spleen because internal organs heat is contained, and gas rushes due to the dispute, and controlling should heat-clearingEliminating dampness, removing toxic substances are main.
The object of the invention is to be achieved through the following technical solutions this Prophylactic chemotherapy instituteThe Chinese medical collutory that causes stomatitis is made up of the Chinese medicine of following weight portion: Brittle Falsepimpernel Herb 3-9 part,Smallleaf desmodium herb 9-15 part, pilosella-leaved drymoglossum herb 15-30 part, star 7-10 part, Thymifoious Euphorbia Herb25-30 part, catchweed bedstraw herb 10-15 part.
Preferred: 6 parts of Brittle Falsepimpernel Herbs, 12 parts of smallleaf desmodium herbs, 22.5 parts of pilosella-leaved drymoglossum herbs, plum blossom8.5 parts of grass, 27 parts of Thymifoious Euphorbia Herbs, 12.5 parts of catchweed bedstraw herbs
Preparation method: make decoction by traditional preparation method's decocting.
Fang Zhong: Brittle Falsepimpernel Herb, smallleaf desmodium herb, pilosella-leaved drymoglossum herb: clearing heat and promoting diuresis, removing toxic substances; Star,Thymifoious Euphorbia Herb: clearing heat and cooling blood, removing toxicity for detumescence; Catchweed bedstraw herb: clearing away damp-heat, eliminating stasis to subdue swelling.
Clinical data
1. physical data in January, 2010-2012 are accepted chemotherapy in hospital in my section year JuneTumour patient 64 examples, male 30 examples, female's 34 examples, 31 years old～68 years old age, average year42 years old age; Wherein, malignant lymphoma 34 examples, breast cancer 28 examples, lung cancer 2 examples, allPatient all makes a definite diagnosis through pathologic finding. Chemotherapy regimen: malignant lymphoma gives CHOP (ringPhosphamide, vincristine, adriamycin, prednisone); Breast cancer gives CMF (ring phosphinylidyneAmine, methotrexate (MTX), fluorouracil), lung cancer give CAP (endoxan, adriamycin,Cis-platinum) scheme chemotherapy. Chemotherapeutics consumption and usage operative norm scheme. By 64 examplesPatient is divided into treatment group and control group at random, every group of each 32 examples, two groups of patient genders,Age, sick kind, chemotherapy regimen used, health are learned by statistics and are processed without statisticsMeaning, has comparativity.
2. diagnostic criteria 0 is spent: oral mucosa is normal. I degree: oral mucosa occurs redSpot, pain; II degree: erythema, ulcer appear in oral mucosa, can enter general diet;III degree: oral mucosa ulcer, can only eat by influent stream; IV degree: occur ulcer, patient is notCan feed.
3. the routine patient of methods for the treatment of treatment group 32 starts to use the present invention from chemotherapy first dayDescribed Chinese medical collutory, take Brittle Falsepimpernel Herb 6g, smallleaf desmodium herb 12g, pilosella-leaved drymoglossum herb 22.5g,Star 8.5g, Thymifoious Euphorbia Herb 27g, catchweed bedstraw herb 12.5g, 400ml～500ml adds waterDecoct into 200ml～300ml, dress aseptic bottle is for subsequent use. Gargle every day 5 times, three after the mealAnd respectively gargle once for 10 o'clock, 16 o'clock. The method of gargling: advise patient at every turn to suck gargle30ml, containing gargling 3min, and with tongue in tooth, cheek, each stirring of palate, after bulging gargling, spue,To chemotherapy one end cycle. Control group 32 examples contain and gargle with Dobell's solution, time, sideThe same experimental group of method. Two groups of patients equal every day is early, respectively brush teeth 1 evening, smoking cessation, wine andPungent irritable food. Make regular check on oral cavity and have or not ulcer and other discomforts, once go outExisting ulcer, except continuing to gargle by above-mentioned time and method, stops early, brush teeth evening, changesDo MC each 1 time sooner or later, ulcer surface ice-glazed sulphur is loose, observes at any time ulcer surface healingSituation, listens attentively to patient main suit.
4. the scorching incidence of two groups of patient's mouths for the treatment of results adopts χ2Inspection, treatment groupStomatitis incidence (9.38%) is starkly lower than control group (25%), and two groups relatively have systemMeter is learned meaning (P < 0.01). Concrete correction data is in table 1.
The table 1 liang scorching incidence comparison of group patient's mouth
Note: with treatment group comparison, P < 0.05.
5. bad reaction: bad reaction does not occur during treatment, and patient all can tolerate.
Detailed description of the invention
Embodiment mono-: take Brittle Falsepimpernel Herb 6g, smallleaf desmodium herb 12g, pilosella-leaved drymoglossum herb 22.5g, plum blossomGrass 8.5g, Thymifoious Euphorbia Herb 27g, catchweed bedstraw herb 12.5g, by traditional preparation method's decoctingMake decoction.
Embodiment bis-: take Brittle Falsepimpernel Herb 3g, smallleaf desmodium herb 9g, pilosella-leaved drymoglossum herb 15g, star10g, Thymifoious Euphorbia Herb 25g, catchweed bedstraw herb 15g, make by traditional preparation method's decoctingDecoction.
Embodiment tri-: take Brittle Falsepimpernel Herb 9g, smallleaf desmodium herb 15g, pilosella-leaved drymoglossum herb 30g, star7g, Thymifoious Euphorbia Herb 30g, catchweed bedstraw herb 10g, make soup by traditional preparation method's decoctingAgent.
Claims (1)
1. a Chinese medical collutory for stomatitis due to Prophylactic chemotherapy, is characterized in that thisChinese medical collutory is made up of the Chinese medicine of following weight: Brittle Falsepimpernel Herb 6g, smallleaf desmodium herb 12g, embraceTree lotus 22.5g, star 8.5g, Thymifoious Euphorbia Herb 27g, catchweed bedstraw herb 12.5g, by passingPreparation method's decocting of system is made decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410286973.6A CN104069240B (en) | 2014-06-16 | 2014-06-16 | The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410286973.6A CN104069240B (en) | 2014-06-16 | 2014-06-16 | The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104069240A CN104069240A (en) | 2014-10-01 |
| CN104069240B true CN104069240B (en) | 2016-05-04 |
Family
ID=51591106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410286973.6A Expired - Fee Related CN104069240B (en) | 2014-06-16 | 2014-06-16 | The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104069240B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667090A (en) * | 2015-02-26 | 2015-06-03 | 姜自远 | Traditional Chinese medicine preparation for preventing toxic and side effects caused by breast cancer chemotherapy |
| CN105362529A (en) * | 2015-11-19 | 2016-03-02 | 隋汝德 | Traditional Chinese medicine mouthwash for treating chemoradiotherapy-induced oral ulcers |
| CN106880660A (en) * | 2017-04-07 | 2017-06-23 | 佳木斯大学 | A kind of medicine for treating canker sore, stomatitis and its preparation method and application |
| CN111011309A (en) * | 2020-03-03 | 2020-04-17 | 江西中医药大学 | Method for establishing chemotherapy drug induced rat oral ulcer model and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361898A (en) * | 2008-09-27 | 2009-02-11 | 郑培秋 | Chinese herbal medicine gargle for preventing and treating AIDS stomatitis |
| CN102688347A (en) * | 2012-06-11 | 2012-09-26 | 张松波 | Traditional Chinese medicine preparation for treating oral inflammation and preparation method thereof |
| CN103656284A (en) * | 2013-11-29 | 2014-03-26 | 周晨 | Traditional Chinese medicine formula for treating oral inflammation |
-
2014
- 2014-06-16 CN CN201410286973.6A patent/CN104069240B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361898A (en) * | 2008-09-27 | 2009-02-11 | 郑培秋 | Chinese herbal medicine gargle for preventing and treating AIDS stomatitis |
| CN102688347A (en) * | 2012-06-11 | 2012-09-26 | 张松波 | Traditional Chinese medicine preparation for treating oral inflammation and preparation method thereof |
| CN103656284A (en) * | 2013-11-29 | 2014-03-26 | 周晨 | Traditional Chinese medicine formula for treating oral inflammation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104069240A (en) | 2014-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101095736B (en) | Chinese traditional medicine composition for treating acute and chronic pharyngitis, tonsillitis and method of making the same | |
| CN104069240B (en) | The Chinese medical collutory of stomatitis due to a kind of Prophylactic chemotherapy | |
| CN103734442A (en) | Dendrobium officinale candy | |
| CN102861199A (en) | Traditional Chinese medicine composition for treating gastroesophageal reflux disease and preparation method | |
| CN105213991B (en) | Traditional Chinese medicine composition for treating gastroesophageal reflux disease | |
| CN103238710A (en) | Food healthcare tea granules for protecting gastric mucosa | |
| CN103638447B (en) | A kind of Chinese medicine composition and application thereof for the treatment of cholecystitis | |
| CN104815311A (en) | Traditional Chinese medicine composition for treating pregnancy sickness and preparation method thereof | |
| CN104524253B (en) | A kind of Chinese medicine composition for treating pregnancy period and women breast-feeding their children's toothache | |
| CN104547125A (en) | Gastrointestinal drug and application thereof | |
| CN102772522A (en) | Traditional Chinese medicine decoction for treating liver-fire epistaxis | |
| CN103238716A (en) | Health tea granules capable of clearing heat from throat | |
| CN103157002B (en) | Pure traditional Chinese medicine composition for treating diabetes mellitus and preparation method for same | |
| CN102755507A (en) | Traditional Chinese medicine decoction for treating acute bronchitis caused by wind dryness damaging lung | |
| CN102657716A (en) | Anti-aging traditional Chinese medicine composition and preparation method thereof | |
| CN102669351A (en) | Liver-nourishing tea electuary for preventing alcoholic liver | |
| CN105998720A (en) | Chinese medicinal preparation for treatment of children bronchial pneumonia and preparation method | |
| CN101607061A (en) | A kind of drug regimen of protecting gastric mucosa and preparation method thereof | |
| CN106692836A (en) | Medicine for preventing and treating stomach upset | |
| CN104587249B (en) | A kind of Chinese medicine composition with the effect of clearing away the lungheat and moisturizing relieving sore-throat and its preparation method and application | |
| CN104666677A (en) | Medicinal composition granule having functions of lowering blood sugar and preparation method thereof | |
| CN104547613A (en) | Application of medicine composition in preparing medicine curing hypertensive nephropathy | |
| CN103877307B (en) | A kind of pharmaceutical composition for preventing and treating chemotherapy induced stomatitis and its application | |
| CN114425075A (en) | New application of Xiaochaihu granules in preventing and treating infantile indigestion with food retention | |
| CN1249949A (en) | Oral Chinese medicine liquid for treating chronic superficial gastritis and its preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Liu Yulian Inventor after: Tian Hongrong Inventor before: Liu Yulian |
|
| CB03 | Change of inventor or designer information | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160504 Termination date: 20180616 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |