CN104068420A - Fishbone powder effervescent tablet - Google Patents
Fishbone powder effervescent tablet Download PDFInfo
- Publication number
- CN104068420A CN104068420A CN201310099910.5A CN201310099910A CN104068420A CN 104068420 A CN104068420 A CN 104068420A CN 201310099910 A CN201310099910 A CN 201310099910A CN 104068420 A CN104068420 A CN 104068420A
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- CN
- China
- Prior art keywords
- effervescent tablet
- fishbone dust
- calcium
- acid
- counted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000007938 effervescent tablet Substances 0.000 title claims abstract description 24
- 239000000843 powder Substances 0.000 title abstract 4
- 239000000428 dust Substances 0.000 claims description 33
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 18
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 10
- 239000005720 sucrose Substances 0.000 claims description 10
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 6
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 6
- 235000015165 citric acid Nutrition 0.000 claims description 6
- 239000000576 food coloring agent Substances 0.000 claims description 6
- 235000011090 malic acid Nutrition 0.000 claims description 6
- 239000001630 malic acid Substances 0.000 claims description 6
- 235000019166 vitamin D Nutrition 0.000 claims description 6
- 239000011710 vitamin D Substances 0.000 claims description 6
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 6
- 229940046008 vitamin d Drugs 0.000 claims description 6
- 235000005979 Citrus limon Nutrition 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 239000000853 adhesive Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 claims description 5
- 239000008116 calcium stearate Substances 0.000 claims description 5
- 235000013539 calcium stearate Nutrition 0.000 claims description 5
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 5
- 239000000314 lubricant Substances 0.000 claims description 5
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 4
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical group CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 4
- 108010011485 Aspartame Proteins 0.000 claims description 4
- 235000016068 Berberis vulgaris Nutrition 0.000 claims description 4
- 241000335053 Beta vulgaris Species 0.000 claims description 4
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 4
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 4
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims description 4
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 4
- 239000000605 aspartame Substances 0.000 claims description 4
- 235000010357 aspartame Nutrition 0.000 claims description 4
- 229960003438 aspartame Drugs 0.000 claims description 4
- 235000013734 beta-carotene Nutrition 0.000 claims description 4
- 239000011648 beta-carotene Substances 0.000 claims description 4
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims description 4
- 229960002747 betacarotene Drugs 0.000 claims description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 4
- 229940085605 saccharin sodium Drugs 0.000 claims description 4
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 4
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 4
- 239000011975 tartaric acid Substances 0.000 claims description 4
- 235000002906 tartaric acid Nutrition 0.000 claims description 4
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims description 4
- MIDXCONKKJTLDX-UHFFFAOYSA-N 3,5-dimethylcyclopentane-1,2-dione Chemical compound CC1CC(C)C(=O)C1=O MIDXCONKKJTLDX-UHFFFAOYSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- 235000013736 caramel Nutrition 0.000 claims description 3
- 239000003086 colorant Substances 0.000 claims description 3
- 239000000377 silicon dioxide Substances 0.000 claims description 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- 235000011054 acetic acid Nutrition 0.000 claims description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 2
- 239000002002 slurry Substances 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- 229960004793 sucrose Drugs 0.000 claims description 2
- 244000248349 Citrus limon Species 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 22
- 239000011575 calcium Substances 0.000 abstract description 22
- 229910052791 calcium Inorganic materials 0.000 abstract description 22
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 18
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract description 11
- 229910052742 iron Inorganic materials 0.000 abstract description 11
- 239000011777 magnesium Substances 0.000 abstract description 11
- 229910052749 magnesium Inorganic materials 0.000 abstract description 11
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 7
- 239000011701 zinc Substances 0.000 abstract description 7
- 229910052725 zinc Inorganic materials 0.000 abstract description 7
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract description 3
- 239000011574 phosphorus Substances 0.000 abstract description 3
- 229910052698 phosphorus Inorganic materials 0.000 abstract description 3
- 239000013589 supplement Substances 0.000 abstract description 3
- 239000003826 tablet Substances 0.000 abstract description 3
- 230000009747 swallowing Effects 0.000 abstract description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 10
- 238000009835 boiling Methods 0.000 description 10
- 239000002245 particle Substances 0.000 description 9
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 8
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 8
- 229910001424 calcium ion Inorganic materials 0.000 description 8
- 238000001035 drying Methods 0.000 description 8
- 229910001425 magnesium ion Inorganic materials 0.000 description 8
- 238000002156 mixing Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 239000012467 final product Substances 0.000 description 5
- 239000004519 grease Substances 0.000 description 5
- 238000002791 soaking Methods 0.000 description 5
- 229910000029 sodium carbonate Inorganic materials 0.000 description 5
- 239000007779 soft material Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- 235000020985 whole grains Nutrition 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 244000131522 Citrus pyriformis Species 0.000 description 4
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 4
- 238000000921 elemental analysis Methods 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- -1 iron ion Chemical class 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 235000013305 food Nutrition 0.000 description 3
- 241000220223 Fragaria Species 0.000 description 2
- 235000016623 Fragaria vesca Nutrition 0.000 description 2
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 239000007968 orange flavor Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000001054 red pigment Substances 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/20—Fish extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to an effervescent tablet, particularly to a fishbone powder effervescent tablet. According to the tablet disclosed by the invention, purely natural fishbone powder is used as a main calcium source, and the purely natural fishbone powder can supplement elements required by a human body, such as calcium, phosphorus, magnesium, iron and zinc; and at the same time, the manner of the effervescent tablet is adopted, so that the effervescent tablet is convenient to take, the mouth feel of the effervescent tablet is good, and the effervescent tablet is especially suitable for old people, children, pregnant women, patients who have difficulties in swallowing, and the patients with poor gastroenteric functions.
Description
Technical field
The present invention relates to a kind of effervescent tablet, particularly a kind of fishbone dust effervescent tablet.
Background technology
Each age groups calcium intake every day that Chinese Soclety of Nutrition is recommended is at 800mg/ days, but combining the 4th " national nutrition and the health survey " conclusion of carrying out according to Ministry of Health of the People's Republic of China, Ministry of Science & Technique of PRC, National Bureau of Statistics of the People's Republic of China shows, China resident's actual intake is less than 400mg/ days, other nutrients of comparing, Gai Shi China resident comparatively lacks.
Calcium supplementing product is on the market multifarious, but the calcium carbonate that most of product is all originated taking mineral is as main calcium source, compared to the calcium carbonate in mineral source, calcium supplementing product taking fishbone dust as main calcium source, more meet the psychological needs that people pursue natural food, health products, in fish-bone, also contain the element that the needed by human body such as a considerable amount of phosphorus, magnesium, iron, zinc are wanted simultaneously, better than simple effect of supplemented calcium.
Simultaneously, the various leisure food made from fish-bone are also a lot of on the market, but as snacks, be difficult to control the content of taking in calcium, too much absorption calcium may cause increase and cylinder electrolyte unbalance that calculi in vivo generates, therefore, develop a kind of health food taking fishbone dust as primary raw material that has fixed dosage and have market potential demand.
Summary of the invention
The technical problem to be solved in the present invention is: a kind of fishbone dust effervescent tablet and preparation method thereof is provided.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of fishbone dust effervescent tablet, is characterized in that every 1000 are grouped into by following one-tenth:
Fishbone dust 500-1500g
Acid source 250-1000g
Glidant 5-10g
Lubricant 10-40g
Flavouring 1-20g
Adhesive 50-200g
Described acid source is selected from the organic or inorganic acid of food stage, and preferred, acid source of the present invention is selected from phosphoric acid, acetic acid, citric acid, malic acid or tartaric acid;
Described glidant is selected from silica or talcum powder;
Described lubricant is selected from dolomol or calcium stearate;
Described flavouring is selected from one or more in Steviosin, Aspartame, saccharin sodium or sucrose;
Described adhesive is selected from starch slurry, sodium carboxymethylcellulose, Hydroxypropyl methylcellulose or PVP.
Preferably, in every effervescent tablet, also contain the vitamin D of 100-300 international unit
3.
Preferably, in every effervescent tablet, also contain the food coloring of 0.01-2mg; Described food coloring can be natural such as beta carotene, beet red, caramel colorant etc., or artificial synthetic as lemon yellow, lure red, sunset yellow, light blue etc.
The flavoring essence that also contains 0.01-2mg in preferred every effervescent tablet, the selection of flavoring essence can be determined according to food coloring, for example beta carotene collocation orange flavor, beet red collocation strawberry essence, caramel colorant collocation lemon extract etc.
Described fishbone dust is commercially available prod, also can prepare voluntarily, and the step of preparation is as follows voluntarily:
The soaking in sodium carbonate solution 30-60min of 10-50g/L for fish-bone, to remove smelling removal and to remove part grease, after washing again under the pressure of 0.1-0.15MPa boiling 5-10min with slaking and softening fish-bone, the fish-bone that boiling completes is placed in drying box dry 30min at 100 DEG C, pulverize afterwards, cross 200 mesh sieves.The fishbone dust particle obtaining through 200 mesh sieves, disintegration better effects if, and do not need additionally to add filler.
The step of film-making is as follows:
After fishbone dust, adhesive and the flavouring of getting respective amount mixes, add 55% ethanol water and make neither too hard, nor too soft soft material, granulate, whole grain, in particle, add glidant and lubricant, optionally add vitamin D simultaneously
3and/or food coloring, and flavoring essence, mix rear compressing tablet, sterilize and get final product.
The invention has the beneficial effects as follows: the present invention has adopted the fishbone dust of pure natural as main calcium source, except supplement calcium, can also supplement the element that the needed by human body such as phosphorus, magnesium, iron, zinc are wanted.Adopt the form of effervescent tablet simultaneously, taking convenience, mouthfeel is better, tablet is water-soluble after effervesce disintegration, can promote calcium dissolving and absorption in vivo, especially be applicable to old man, child, pregnant woman, the difficulty of swallowing and the poor patient of gastrointestinal function, can reduce medicine to GI burden, wherein old man, child, the pregnant woman colony more to calcium demand just.
Detailed description of the invention
Now in conjunction with specific embodiments, the present invention is further detailed explanation.
Embodiment 1
Adopt self-control fishbone dust, the soaking in sodium carbonate solution 30min of 50g/L for fish-bone, to remove smelling removal and to remove part grease, after washing again under the pressure of 0.15MPa boiling 5min with slaking and softening fish-bone, the fish-bone that boiling completes is placed in drying box dry 30min at 100 DEG C, pulverize afterwards, cross 200 mesh sieves.Results of elemental analyses shows that in fishbone dust, calcium content is counted 152g/kg with calcium ion, and content of magnesium is counted 3g/kg with magnesium ion, and zinc content is counted 98mg/kg with zinc ion, and iron content is counted 49mg/kg with iron ion.
Get fishbone dust 1000g, malic acid 600g, saccharin sodium 0.8g and sucrose 0.2g, after mixing, get 100g sodium carboxymethylcellulose and be made into ethanolic solution, fishbone dust, malic acid, saccharin sodium and sucrose are made to neither too hard, nor too soft soft material, granulation, whole grain, in particle, add talcum powder 10g and calcium stearate 20g, after mixing, be pressed into 1000, sterilize and get final product.Every calcium content is counted 152mg with calcium ion, and content of magnesium is counted 3mg with magnesium ion.
Embodiment 2
Adopt self-control fishbone dust, the soaking in sodium carbonate solution 60min of 10g/L for fish-bone, to remove smelling removal and to remove part grease, after washing again under the pressure of 0.1MPa boiling 5min with slaking and softening fish-bone, the fish-bone that boiling completes is placed in drying box dry 30min at 100 DEG C, pulverize afterwards, cross 200 mesh sieves.Results of elemental analyses shows that in fishbone dust, calcium content is counted 152g/kg with calcium ion, and content of magnesium is counted 3g/kg with magnesium ion, and zinc content is counted 98mg/kg with zinc ion, and iron content is counted 49mg/kg with iron ion.
Get fishbone dust 500g, malic acid 250g, Steviosin 1.0g and sucrose 9.0g, after mixing, get 50g sodium carboxymethylcellulose and be made into ethanolic solution, after being mixed, fishbone dust, malic acid, Steviosin and sucrose makes neither too hard, nor too soft soft material, granulate, be dried, 0.1g lemon extract is dissolved in ethanol, is evenly sprayed on the particle of drying, whole grain, in particle, add silica 5g, dolomol 10g and lemon yellow 0.1g, after mixing, be pressed into 1000, sterilize and get final product.Every calcium content is counted 76mg with calcium ion, and content of magnesium is counted 1.5mg with magnesium ion.
Embodiment 3
Adopt self-control fishbone dust, the soaking in sodium carbonate solution 30min of 50g/L for fish-bone, to remove smelling removal and to remove part grease, after washing again under the pressure of 0.15MPa boiling 5min with slaking and softening fish-bone, the fish-bone that boiling completes is placed in drying box dry 30min at 100 DEG C, pulverize afterwards, cross 200 mesh sieves.Results of elemental analyses shows that in fishbone dust, calcium content is counted 152g/kg with calcium ion, and content of magnesium is counted 3g/kg with magnesium ion, and zinc content is counted 98mg/kg with zinc ion, and iron content is counted 49mg/kg with iron ion.
Get fishbone dust 800g, citric acid 700g, Aspartame 2.5g and sucrose 2.5g, after mixing, get 100g hydroxypropyl cellulose and be made into ethanolic solution, after being mixed, fishbone dust, citric acid, Aspartame and sucrose makes neither too hard, nor too soft soft material, granulate, be dried, 0.5g orange flavor is dissolved in ethanol, evenly be sprayed on the particle of drying, whole grain, adds talcum powder 8g, calcium stearate 24g, beta carotene 2g and 2.5mg vitamin D in particle
3, after mixing, be pressed into 1000, sterilize and get final product.Every calcium content is counted 121mg with calcium ion, and content of magnesium is counted 2.4mg with magnesium ion, vitamin D
3100 international units.
Embodiment 4
Adopt self-control fishbone dust, the soaking in sodium carbonate solution 30min of 50g/L for fish-bone, to remove smelling removal and to remove part grease, after washing again under the pressure of 0.15MPa boiling 5min with slaking and softening fish-bone, the fish-bone that boiling completes is placed in drying box dry 30min at 100 DEG C, pulverize afterwards, cross 200 mesh sieves.Results of elemental analyses shows that in fishbone dust, calcium content is counted 152g/kg with calcium ion, and content of magnesium is counted 3g/kg with magnesium ion, and zinc content is counted 98mg/kg with zinc ion, and iron content is counted 49mg/kg with iron ion.
Get fishbone dust 1500g, tartaric acid 300g, citric acid 700g, Steviosin 5.0g and sucrose 15.0g, after mixing, get 200g hydroxypropyl cellulose and be made into ethanolic solution, after being mixed, fishbone dust, citric acid, tartaric acid, Steviosin and sucrose makes neither too hard, nor too soft soft material, granulate, be dried, 1.0g strawberry essence is dissolved in ethanol, evenly be sprayed at whole grain on the particle of drying, in particle, add talcum powder 8g, calcium stearate 24g, beet red pigment 1.5g and 7.5mg vitamin D
3, after mixing, be pressed into 1000, sterilize and get final product.Every calcium content is counted 181mg with calcium ion, and content of magnesium is counted 4.0mg with magnesium ion, vitamin D
3300 international units.
Claims (5)
1. a fishbone dust effervescent tablet, is characterized in that every 1000 are grouped into by following one-tenth:
Fishbone dust 500-1500g
Acid source 250-1000g
Glidant 5-10g
Lubricant 10-40g
Flavouring 1-20g
Adhesive 50-200g
Described acid source is selected from one or more in acetic acid, citric acid, malic acid, tartaric acid;
Described glidant is selected from silica or talcum powder;
Described lubricant is selected from dolomol or calcium stearate;
Described flavouring is selected from one or more in Steviosin, Aspartame, saccharin sodium or sucrose;
Described adhesive is selected from starch slurry, sodium carboxymethylcellulose, Hydroxypropyl methylcellulose or PVP.
2. fishbone dust effervescent tablet as described in claim 1, is characterized in that also containing in every effervescent tablet the vitamin D of 100-300 international unit
3.
3. the fishbone dust effervescent tablet described in claim 1 or 2, is characterized in that also containing in every effervescent tablet the food coloring of 0.01-2mg.
4. fishbone dust effervescent tablet as described in claim 3, is characterized in that described food coloring is beta carotene, beet red, caramel colorant or lemon yellow.
5. fishbone dust effervescent tablet as described in claim 3, is characterized in that also containing in every effervescent tablet the essence of 0.01-2mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310099910.5A CN104068420A (en) | 2013-03-27 | 2013-03-27 | Fishbone powder effervescent tablet |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310099910.5A CN104068420A (en) | 2013-03-27 | 2013-03-27 | Fishbone powder effervescent tablet |
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| CN104068420A true CN104068420A (en) | 2014-10-01 |
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| CN201310099910.5A Pending CN104068420A (en) | 2013-03-27 | 2013-03-27 | Fishbone powder effervescent tablet |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020263207A3 (en) * | 2019-06-24 | 2021-10-07 | Yaşar Üni̇versi̇tesi̇ | Gluten/gluten free pasta enriched with fish meat and fishbone powder |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091324A (en) * | 2011-03-15 | 2011-06-15 | 徐世祥 | Calcium for nourishing bones |
| CN102293253A (en) * | 2011-07-07 | 2011-12-28 | 天津农学院 | Preparation method of fishbone calcium milk tablets |
| CN102716149A (en) * | 2011-12-22 | 2012-10-10 | 邵爱霞 | Calcium carbonate-D3 effervescent tablet and preparation method thereof |
-
2013
- 2013-03-27 CN CN201310099910.5A patent/CN104068420A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091324A (en) * | 2011-03-15 | 2011-06-15 | 徐世祥 | Calcium for nourishing bones |
| CN102293253A (en) * | 2011-07-07 | 2011-12-28 | 天津农学院 | Preparation method of fishbone calcium milk tablets |
| CN102716149A (en) * | 2011-12-22 | 2012-10-10 | 邵爱霞 | Calcium carbonate-D3 effervescent tablet and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020263207A3 (en) * | 2019-06-24 | 2021-10-07 | Yaşar Üni̇versi̇tesi̇ | Gluten/gluten free pasta enriched with fish meat and fishbone powder |
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Application publication date: 20141001 |