CN104066444A - 微粒疫苗制剂 - Google Patents

微粒疫苗制剂 Download PDF

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Publication number
CN104066444A
CN104066444A CN201280055234.5A CN201280055234A CN104066444A CN 104066444 A CN104066444 A CN 104066444A CN 201280055234 A CN201280055234 A CN 201280055234A CN 104066444 A CN104066444 A CN 104066444A
Authority
CN
China
Prior art keywords
antigen
seq
antigens
vaccine formulation
clauses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280055234.5A
Other languages
English (en)
Chinese (zh)
Inventor
F.贝杜-阿多
G.孔
E.雅各布森
C.默瑟
K.约翰逊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PDS Biotechnology Corp
Original Assignee
PDS Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PDS Biotechnology Corp filed Critical PDS Biotechnology Corp
Priority to CN201910145079.XA priority Critical patent/CN110075292A/zh
Publication of CN104066444A publication Critical patent/CN104066444A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CN201280055234.5A 2011-09-12 2012-09-12 微粒疫苗制剂 Pending CN104066444A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910145079.XA CN110075292A (zh) 2011-09-12 2012-09-12 微粒疫苗制剂

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161533512P 2011-09-12 2011-09-12
US61/533,512 2011-09-12
PCT/US2012/054786 WO2013039989A1 (en) 2011-09-12 2012-09-12 Particluate vaccine formulations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910145079.XA Division CN110075292A (zh) 2011-09-12 2012-09-12 微粒疫苗制剂

Publications (1)

Publication Number Publication Date
CN104066444A true CN104066444A (zh) 2014-09-24

Family

ID=47883670

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201280055234.5A Pending CN104066444A (zh) 2011-09-12 2012-09-12 微粒疫苗制剂
CN201910145079.XA Pending CN110075292A (zh) 2011-09-12 2012-09-12 微粒疫苗制剂

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201910145079.XA Pending CN110075292A (zh) 2011-09-12 2012-09-12 微粒疫苗制剂

Country Status (8)

Country Link
US (2) US20150110823A1 (enrdf_load_stackoverflow)
EP (1) EP2755680B1 (enrdf_load_stackoverflow)
JP (2) JP6600459B2 (enrdf_load_stackoverflow)
CN (2) CN104066444A (enrdf_load_stackoverflow)
ES (1) ES2689799T3 (enrdf_load_stackoverflow)
PL (1) PL2755680T3 (enrdf_load_stackoverflow)
TW (1) TWI673062B (enrdf_load_stackoverflow)
WO (1) WO2013039989A1 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113557035A (zh) * 2019-01-12 2021-10-26 卫理公会医院 自组装肽纳米颗粒和其用途

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
AU2009236306B2 (en) 2008-04-17 2015-04-02 Pds Biotechnology Corporation Stimulation of an immune response by enantiomers of cationic lipids
JP6600459B2 (ja) * 2011-09-12 2019-10-30 ピーディーエス バイオテクノロジー コーポレイション 粒子状ワクチン製剤
RU2649365C2 (ru) 2012-06-15 2018-04-02 ПиДиЭс БАЙОТЕКНОЛОДЖИ КОРПОРЭЙШН Вакцинные композиции с катионными липидами и способы применения
AU2013317805B2 (en) 2012-09-21 2018-07-26 Pds Biotechnology Corporation Improved vaccine compositions and methods of use
US11612652B2 (en) 2015-11-13 2023-03-28 Pds Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
EP3522908A4 (en) * 2016-10-05 2020-06-24 PDS Biotechnology Corporation INNOVATIVE HPV16 NON-HLA-RESTRICTED T-CELL VACCINES, COMPOSITIONS AND METHODS FOR USE THEREOF
WO2018067822A1 (en) * 2016-10-05 2018-04-12 Pds Biotechnology Corporation Methods to alter the tumor microenvironment for effective cancer immunotherapy
WO2021085696A1 (ko) * 2019-11-01 2021-05-06 한국과학기술원 작은 지질 나노 입자 및 이를 포함하는 암 백신
JPWO2023145749A1 (enrdf_load_stackoverflow) * 2022-01-27 2023-08-03
EP4511061A1 (en) 2022-04-22 2025-02-26 Universitat Autònoma de Barcelona Immunogenic composition with protein micro- and nanoparticles

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1909918A (zh) * 2004-02-20 2007-02-07 中国农业大学 T细胞免疫反应抑制剂
US20100221223A1 (en) * 2002-09-30 2010-09-02 Astellas Pharma Inc. Immune response induction method
CN102137675A (zh) * 2008-04-17 2011-07-27 Pds生物科技公司 通过阳离子脂质的对映体刺激免疫应答

Family Cites Families (14)

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US6183745B1 (en) * 1990-12-12 2001-02-06 The University Of Queensland Subunit papilloma virus vaccine and peptides for use therein
AUPM500494A0 (en) * 1994-04-12 1994-05-05 Minister For Agriculture & Rural Affairs For The State Of New South Wales, The Composition for use in increasing mucosal immunity
CA2227065A1 (en) * 1995-07-21 1997-02-06 Rhone-Poulenc Rorer Pharmaceuticals Inc. Adeno-associated viral liposomes and their use in transfecting dendritic cells to stimulate specific immunity
FR2794370B1 (fr) * 1999-06-03 2003-10-17 Biovector Therapeutics Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination
US20020187105A1 (en) * 2001-02-01 2002-12-12 Yiyu Zou Polymer combinations that result in stabilized aerosols for gene delivery to the lungs
EP2481422A3 (en) * 2003-09-03 2013-04-03 Dendritherapeutics, Inc. Multiplex vaccines
US7303881B2 (en) * 2004-04-30 2007-12-04 Pds Biotechnology Corporation Antigen delivery compositions and methods of use
DE102004057303A1 (de) * 2004-11-26 2006-06-01 Merck Patent Gmbh Stabile Kristallmodifikationen von DOTAP Chlorid
WO2007022152A2 (en) * 2005-08-15 2007-02-22 The Research Foundation Of State University Of New York Lipid nano particulates containing antigens as cancer vaccines
CA2630220C (en) * 2005-11-22 2020-10-13 Doris Coit Norovirus and sapovirus antigens
JP2007238559A (ja) * 2006-03-10 2007-09-20 Nagoya City Univ 未成熟樹状細胞活性化剤及びその使用
US8877206B2 (en) * 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
WO2011109294A1 (en) * 2010-03-01 2011-09-09 Dicerna Pharmaceuticals, Inc. Lipid delivery formulations
JP6600459B2 (ja) * 2011-09-12 2019-10-30 ピーディーエス バイオテクノロジー コーポレイション 粒子状ワクチン製剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100221223A1 (en) * 2002-09-30 2010-09-02 Astellas Pharma Inc. Immune response induction method
CN1909918A (zh) * 2004-02-20 2007-02-07 中国农业大学 T细胞免疫反应抑制剂
CN102137675A (zh) * 2008-04-17 2011-07-27 Pds生物科技公司 通过阳离子脂质的对映体刺激免疫应答

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113557035A (zh) * 2019-01-12 2021-10-26 卫理公会医院 自组装肽纳米颗粒和其用途
CN113557035B (zh) * 2019-01-12 2025-09-05 卫理公会医院 自组装肽纳米颗粒和其用途

Also Published As

Publication number Publication date
EP2755680B1 (en) 2018-07-04
EP2755680A1 (en) 2014-07-23
JP6600459B2 (ja) 2019-10-30
PL2755680T3 (pl) 2019-03-29
CN110075292A (zh) 2019-08-02
ES2689799T3 (es) 2018-11-15
WO2013039989A1 (en) 2013-03-21
EP2755680A4 (en) 2015-04-15
JP2014527965A (ja) 2014-10-23
JP2018065821A (ja) 2018-04-26
US20190275145A1 (en) 2019-09-12
US20150110823A1 (en) 2015-04-23
TW201317001A (zh) 2013-05-01
TWI673062B (zh) 2019-10-01

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20140924

RJ01 Rejection of invention patent application after publication