CN104056230A - Traditional Chinese medicinal composition for treating heart-spleen deficiency type insomnia - Google Patents
Traditional Chinese medicinal composition for treating heart-spleen deficiency type insomnia Download PDFInfo
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- CN104056230A CN104056230A CN201410288686.9A CN201410288686A CN104056230A CN 104056230 A CN104056230 A CN 104056230A CN 201410288686 A CN201410288686 A CN 201410288686A CN 104056230 A CN104056230 A CN 104056230A
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating insomnia. The composition is prepared from astragalus membranaceus, Chinese angelica, cinnamon, roasted liquorice, ginseng, longan pulp, fried jujube kernel, Chinese date and other traditional Chinese medicinal materials. The medicinal materials are treated by a traditional decoction method to obtain decoction for patients; the astragalus membranaceus and the longan pulp are monarch drugs to play the effects of tonifying heart and spleen, as well as nourishing blood and tranquilizing the mind; the medicinal materials are compatible to play the effects of nourishing spleen-qi, and nourishing heart blood to tranquilize the mind, so that the traditional Chinese medicinal composition has an excellent curative effect on insomnia caused by heart-spleen deficiency.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition of Cure for insomnia.
Background technology
Insomnia refers to fall asleep and maybe cannot keep sleep state, causes not having enough sleep.Claim again DIMS (D1MS), for a variety of causes causes that difficulty falling asleep, Depth of sleep or frequency are too short, early awakening and the length of one's sleep not enough or of poor quality etc., be a kind of commonly encountered diseases.Insomnia tends to bring great misery and psychological burden to patient, can damage other every aspects of health because of abuse insomnia drug again, though do not belong to critical illness, but hinder people orthobiosis, work, study and health, and can increase the weight of or bring out the diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy.Obstinate insomnia, brings long-term misery to patient, even forms the dependence to the medicine of sleeping peacefully, and long-term taking is slept peacefully, medicine can cause iatrogenic disease, is therefore one of major disease of facing of human needs.
In existing Therapeutic Method, generally adopt sleeping pill to help patient and fall asleep, but the sleep of taking after sleeping pill is different from physiologic sleep, but passive sleep.Therefore, even if fall asleep whole night after taking medicine, wake up and still can feel tired, as mentioned above simultaneously, because sleeping pill is general in vivo mostly through liver, renal metabolism, long-term taking can increase the burden of Liver and kidney, have also can cause liver enlargement, hepatalgia, jaundice, edema, albuminuria, hematuria and feel sick, hepatic and renal function injure and the intestines and stomach reaction such as abdominal distention, inappetence, constipation.Some sleeping pill also can cause lassitude, the hypophrenia, and the accumulate poisoning symptoms such as blood pressure drops even cause respiratory and circulatory function obstacle situation, and therefore unsuitable life-time service also cannot fundamentally play the object of Cure for insomnia.The traditional Chinese medical science thinks that insomnia can be divided into five types, and wherein deficiency of both the heart and spleen is very common one type, and therefore how carrying out Cure for insomnia in conjunction with this disease becomes one of present problem that needs solution.
Summary of the invention
The many weak points that exist for existing medicament for treating insomnia, inventor is in conjunction with motherland's traditional medical theory, for type of deficiency of both the heart and spleen, insomnia provides a kind of Chinese medicine composition of brand-new Cure for insomnia, adopt the Radix Astragali, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Glycyrrhizae Preparata, Radix Ginseng, Arillus Longan, Semen Ziziphi Spinosae (parched), the Chinese crude drugs such as Fructus Jujubae, adopt traditional water decocting method to obtain medicinal liquid for patient, wherein taking the Radix Astragali and Arillus Longan as monarch drug, play invigorating the heart and spleen, the drug effect of nourishing blood to tranquillize the mind, all medicines share and can better play enriching spleen-QI, the effect of blood to calm the nerves of nourishing heart, the insomnia causing because of deficiency of both the heart and spleen is had to splendid curative effect.
The present invention for insomnia be mainly by deficiency of both the heart and spleen, due to insufficiency of vital energy and blood: heart storing spirit and main blood, the main think of of spleen and the blood of uniting is pondered over overstrain, damage heart spleen; Taste are source of generating QI and blood, insufficiency of the spleen weakness of QI insufficiency of blood, the heart without support, can not house mind, thus be difficult for falling asleep, dreaming often and waking easily, palpitation and amnesia; Deficiency of qi and blood, clear YANG failing to ascend, can not on give in brain, have a dizzy spell.Blood deficiency can not go up flourish in face, therefore lustreless complexion; Dysfunction of the spleen in transportation, inability of food and drink to be digested and transported, poor appetite, abdominal distention loose stool; The insufficiency of blood deficiency of vital energy, thus lassitude, extremity asthenia, thready and weak pulse; For above-mentioned disease, inventor forms in conjunction with the Traditional Chinese Medicine theoretical configuration of curing the disease.
The each component of this medicine is according to weight portion meter, and its proportioning is: Radix Astragali 13-15 part, Radix Angelicae Sinensis 10-12 part, Cortex Cinnamomi 6-8 part, Radix Glycyrrhizae Preparata 6-8 part, Radix Ginseng 4-6 part, Poria cum Radix Pini 10-12 part, Rhizoma Chuanxiong 8-10 part, Radix Aucklandiae 5-6 part, Rhizoma Atractylodis Macrocephalae 12-13 part, Radix Polygalae 7-9 part, Rhizoma Zingiberis Recens 6-9 part, Arillus Longan 11-14 part, Semen Ziziphi Spinosae (parched) 12-15 part, Fructus Jujubae 7-9 part.
Further, inventor is optimized for prescription:
15 parts of the Radixs Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Cinnamomis, 6 parts of Radix Glycyrrhizae Preparatas, 6 parts of Radix Ginsengs, 12 parts of Poria cum Radix Pinis, 9 parts of Rhizoma Chuanxiongs, 6 parts of the Radix Aucklandiae, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Radix Polygalaes, 6 parts, Rhizoma Zingiberis Recens, 12 parts of Arillus Longans, 15 parts of Semen Ziziphi Spinosae (parched)s, 9 parts, Fructus Jujubae.
In said components, the sweet tepor of the Radix Astragali, returns lung, spleen channel, invigorating the spleen and replenishing QI; The sweet temperature of Arillus Longan, GUIXIN, spleen channel, can enriching spleen-QI, and the blood that can nourish heart again, to calm the nerves, is monarch drug altogether;
Radix Ginseng, the sweet temperature gas supplementing of the Rhizoma Atractylodis Macrocephalae, match with the Radix Astragali, strengthens the merit of invigorating the spleen and replenishing QI; The sweet pungent tepor of Radix Angelicae Sinensis, nourishing blood and nutrient QI, with Arillus Longan phase 5, increases the effect that reinforcing the heart is nourished blood, and is ministerial drug;
Poria cum Radix Pini, Semen Ziziphi Spinosae, Radix Polygalae mind tranquilizing and the heart calming; Muxiangliqi is amusing, and Rhizoma Chuanxiong blood-activating and qi-promoting, with benefiting qi and nourishing blood medicine compatibility, tonify without causing stagnation, is mended and do not hindered stomach; Cortex Cinnamomi is pungent sweet and hot, enters spleen, kidney, the heart, Liver Channel, can mend fire supporing yang, and promoting the flow of QI-blood by warming the meridian, with the drugs for tonifying Qi and blood such as the Radix Astragali, Arillus Longan phase 5, is inspired QI and blood growth, is all adjuvant drug.
Radix Glycyrrhizae Preparata air making-up and spleen enlivening, coordinating the actions of various ingredients in a prescription, for making medicine; With Rhizoma Zingiberis Recens, Fructus Jujubae the spleen and stomach regulating, conveniently take as a means of biochemistry.
By adjusting the proportioning between each component, make full side's monarch clearly demarcated, compatibility purpose is rigorous simultaneously, play invigorating the spleen and replenishing QI, effect that reinforcing the heart is nourished blood simultaneously can the spleen and stomach regulating, reduces side effects of pharmaceutical drugs, and finally for type of deficiency of both the heart and spleen, insomnia has good curative effect.
Compared with prior art, the present invention has strengthened the effectiveness, particularly Rhizoma Chuanxiong of prescription blood-activating and qi-promoting and adding and dose control of Cortex Cinnamomi, has realized above-mentioned effect, has filled up the blank of prior art.
The concrete decocting method of said medicine is: the medicine of recipe quantity is placed in to marmite, adds water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then added water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
Amount of liquid in above-mentioned preparation method converts while being 1g according to weight portion in prescription.
The medicinal liquid patient who adopts said method to obtain can directly take, and without the side effect of similar Western medicine, can make that patient is relieved to take.
In sum, prescription provided by the present invention, select medicine evident in efficacy to coordinate patent medicine, full side's monarch is clearly demarcated, and compatibility purpose is rigorous, plays invigorating the heart and spleen, the drug effect of nourishing blood to tranquillize the mind, all medicines share and can better play enriching spleen-QI, and the effect of blood to calm the nerves of nourishing heart, has splendid curative effect to the insomnia causing because of deficiency of both the heart and spleen.
Detailed description of the invention
Embodiment 1
A medicine for Cure for insomnia, the each component of this medicine is according to weight portion meter, and its proportioning is: 15 parts of the Radixs Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Cinnamomis, 6 parts of Radix Glycyrrhizae Preparatas, 6 parts of Radix Ginsengs, 12 parts of Poria cum Radix Pinis, 9 parts of Rhizoma Chuanxiongs, 6 parts of the Radix Aucklandiae, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Radix Polygalaes, 6 parts, Rhizoma Zingiberis Recens, 12 parts of Arillus Longans, 15 parts of Semen Ziziphi Spinosae (parched)s, 9 parts, Fructus Jujubae; Every part of 1g;
By decocting method be:
The medicine of recipe quantity is placed in to marmite, adds water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then add water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
Embodiment 2
A medicine for Cure for insomnia, the each component of this medicine is according to weight portion meter, and its proportioning is: 13 parts of the Radixs Astragali, 10 parts of Radix Angelicae Sinensis, 7 parts of Cortex Cinnamomis, 8 parts of Radix Glycyrrhizae Preparatas, 4 parts of Radix Ginsengs, 10 parts of Poria cum Radix Pinis, 10 parts of Rhizoma Chuanxiongs, 6 parts of the Radix Aucklandiae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts of Radix Polygalaes, 7 parts, Rhizoma Zingiberis Recens, 11 parts of Arillus Longans, 12 parts of Semen Ziziphi Spinosae (parched)s, 7 parts, Fructus Jujubae; Every part of 1g;
By decocting method be:
The medicine of recipe quantity is placed in to marmite, adds water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then add water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
Embodiment 3
A medicine for Cure for insomnia, the each component of this medicine is according to weight portion meter, and its proportioning is: 14 parts of the Radixs Astragali, 11 parts of Radix Angelicae Sinensis, 8 parts of Cortex Cinnamomis, 7 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Ginsengs, 11 parts of Poria cum Radix Pinis, 8 parts of Rhizoma Chuanxiongs, 5 parts of the Radix Aucklandiae, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Radix Polygalaes, 8 parts, Rhizoma Zingiberis Recens, 14 parts of Arillus Longans, 13 parts of Semen Ziziphi Spinosae (parched)s, 8 parts, Fructus Jujubae; Every part of 1g;
By decocting method be:
The medicine of recipe quantity is placed in to marmite, adds water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then add water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
Embodiment 4
A medicine for Cure for insomnia, the each component of this medicine is according to weight portion meter, and its proportioning is: 15 parts of the Radixs Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Cinnamomis, 6 parts of Radix Glycyrrhizae Preparatas, 6 parts of Radix Ginsengs, 12 parts of Poria cum Radix Pinis, 9 parts of Rhizoma Chuanxiongs, 6 parts of the Radix Aucklandiae, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Radix Polygalaes, 9 parts, Rhizoma Zingiberis Recens, 13 parts of Arillus Longans, 14 parts of Semen Ziziphi Spinosae (parched)s, 8 parts, Fructus Jujubae; Every part of 1g;
By decocting method be:
The medicine of recipe quantity is placed in to marmite, adds water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then add water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
Experimental example
Choose patient medical history totally 60 examples.Be divided at random treatment group 30 examples, matched group 30 examples.
In " traditional Chinese medical science disease Standardization of diagnosis and curative effect (1994) " that wherein patient works out with reference to State Administration of Traditional Chinese Medicine, the diagnostic criteria of " being insomnia ", is all defined as type of deficiency of both the heart and spleen and is insomnia, namely type of deficiency of both the heart and spleen insomnia.
The medicine that treatment group adopts embodiment 1 to obtain is treated, and every day, potion was taken at twice;
Matched group adopts the each 2mg of Chinese mugwort department mile logical sequence, 1 time on the one;
Be 6 weeks medicine time;
Criterion is as follows:
(1) clinical recovery: recover normal or Nighttime sleep the length of one's sleep more than 6 hours, sleep deep, hale and hearty after waking up;
(2) effective: sleep is clearly better, increase the length of one's sleep more than 3 hours, Depth of sleep increases;
(3) effective: symptom alleviates, increase less than 3 hour before the length of one's sleep;
(4) invalid: after treatment, insomnia is not improved or the anti-severe one that adds.
The evaluation of clinical curative effect of taking medicine after 6 weeks is as following table:
Known by above-mentioned data, for type of deficiency of both the heart and spleen, insomnia has splendid curative effect to Chinese medicine provided by the present invention, for adopting the matched group of western medicine, medicine effective percentage of the present invention is higher, and can fundamentally cure insomnia and realize clinical recovery, and in matched group, do not have recovery from illness case, the effect that cannot reach recovery from illness only can realize alleviating of symptom, visible Western medicine only can play the effect of curing the symptoms, not the disease for the treatment of insomnia, far apart with medicine effect provided by the present invention, and medicine of the present invention is free from side effects, the drug dependence that there is no a similar Chinese mugwort department mile logical sequence with after can be not repeatedly.
Claims (3)
1. a Chinese medicine composition for the treatment of type of deficiency of both the heart and spleen insomnia, is characterized in that: the each component of this medicine is according to weight portion meter, and its proportioning is: Radix Astragali 13-15 part, Radix Angelicae Sinensis 10-12 part, Cortex Cinnamomi 6-8 part, Radix Glycyrrhizae Preparata 6-8 part, Radix Ginseng 4-6 part, Poria cum Radix Pini 10-12 part, Rhizoma Chuanxiong 8-10 part, Radix Aucklandiae 5-6 part, Rhizoma Atractylodis Macrocephalae 12-13 part, Radix Polygalae 7-9 part, Rhizoma Zingiberis Recens 6-9 part, Arillus Longan 11-14 part, Semen Ziziphi Spinosae (parched) 12-15 part, Fructus Jujubae 7-9 part.
2. Chinese medicine composition according to claim 1, is characterized in that: the each component of this medicine is according to weight portion meter, and its proportioning is: 15 parts of the Radixs Astragali, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Cinnamomis, 6 parts of Radix Glycyrrhizae Preparatas, 6 parts of Radix Ginsengs, 12 parts of Poria cum Radix Pinis, 9 parts of Rhizoma Chuanxiongs, 6 parts of the Radix Aucklandiae, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Radix Polygalaes, 6 parts, Rhizoma Zingiberis Recens, 12 parts of Arillus Longans, 15 parts of Semen Ziziphi Spinosae (parched)s, 9 parts, Fructus Jujubae.
3. the method for Chinese medicine composition described in processing claim 1, is characterized in that: its step is as follows:
By in prescription every part be 1g, the medicine of recipe quantity is placed in to marmite, add water and cover powder 2cm, soak 20 minutes, when slow fire boiling is 100ml to medicinal liquid surplus, medicinal liquid is poured out, and then add water and cover powder 2cm, slow fire boiling to medicinal liquid surplus is 50ml; Get final product elimination medicinal residues, merge and filter gained medicinal liquid acquisition target medicinal liquid for twice.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108607040A (en) * | 2018-06-21 | 2018-10-02 | 浙江美丽禾生物科技有限公司 | A kind of Chinese medicine preparation and preparation method for treating postpartum insomnia |
| CN112439038A (en) * | 2019-09-04 | 2021-03-05 | 王忠民 | Medicine for quickly improving sleep |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1823992A (en) * | 2005-12-15 | 2006-08-30 | 北京阜康仁生物制药科技有限公司 | Ginseny spleen invigorating preparation and its new preparation method |
| WO2012027882A1 (en) * | 2010-08-30 | 2012-03-08 | 河北以岭医药研究院有限公司 | Pharmaceutical composition for treating insomnia and preparation method thereof |
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2014
- 2014-06-26 CN CN201410288686.9A patent/CN104056230B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1823992A (en) * | 2005-12-15 | 2006-08-30 | 北京阜康仁生物制药科技有限公司 | Ginseny spleen invigorating preparation and its new preparation method |
| WO2012027882A1 (en) * | 2010-08-30 | 2012-03-08 | 河北以岭医药研究院有限公司 | Pharmaceutical composition for treating insomnia and preparation method thereof |
Non-Patent Citations (3)
| Title |
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| 刘启泉: "《袖珍方剂手册》", 31 March 1996, 河北科学技术出版社 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108607040A (en) * | 2018-06-21 | 2018-10-02 | 浙江美丽禾生物科技有限公司 | A kind of Chinese medicine preparation and preparation method for treating postpartum insomnia |
| CN112439038A (en) * | 2019-09-04 | 2021-03-05 | 王忠民 | Medicine for quickly improving sleep |
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