CN104043066B - Chinese herbal extract for promoting hair growth and hair blacking and improving dandruff and application thereof - Google Patents
Chinese herbal extract for promoting hair growth and hair blacking and improving dandruff and application thereof Download PDFInfo
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- CN104043066B CN104043066B CN201310081198.6A CN201310081198A CN104043066B CN 104043066 B CN104043066 B CN 104043066B CN 201310081198 A CN201310081198 A CN 201310081198A CN 104043066 B CN104043066 B CN 104043066B
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Abstract
The invention discloses a Chinese herbal extract for promoting hair growth and hair blacking and improving dandruff and application thereof. The extract is obtained by extraction of bulk drugs containing ginseng, American ginseng, polygonum multiflorum, rhubarb, dodder and other 57 traditional Chinese medicines. Specifically, each of the traditional Chinese medicines accounts for 0.5wt%-30wt%, and the total composition of the traditional Chinese medicines is 100wt%. The bulk drugs are grinded into powder, the powder is mixed with an organic solvent and water, and then extraction is carried out to obtain the Chinese herbal extract. After extraction, the bulk drugs can release a restoration leading factor, which can promote cell activation and has the function of promoting cell proliferation. Thus, the Chinese herbal extract provided by the invention can be applied to activation of hair follicle cells, activation of melanin cells and other aspects, and can be used as a skin, hair follicle and hair medicine related to the fields, or can be used as an active and auxiliary component of cosmeceutical products associated with the fields.
Description
Technical field
The present invention relates to a kind of Chinese herbal medicine extract, more particularly to a kind of being applied to promote hair growth promoting, hair color and improve scalp
The Chinese herbal medicine extract of bits, with the function of promoting cell activation and hypertrophy.
Background technology
Hair for human, except it is warming, protection scalp function in addition to, also with the work for making appearance expression attractive in appearance
With.And due to by the disease such as heredity, hormone hormone, hyperthyroidism, lupus erythematosus, syphilis or health factor
Impact can cause hair gradually to drop；And scalp infection or the inflammation such as tinea capitis, folliculitises, contact atopic dermatitis, can also produce
Send out.In addition, various bodies and produced by psychological factor pressure also can all affect growing up healthy and sound or causing alopecia for hair.Extremely
In hoary-headed reason, the origin cause of formation medically studied is mainly the melanin in hair follicle with caused by aging reduction.Also have
Because drinking and eating irregularly, pressure is excessive, and external force caused by, such as it is excessive or it is abnormal it is whole scald, injury is produced to hair.
In addition disease is likely to cause poliosis, such as anemia.No doubt have at present many medical skill for aforementioned alopecia and poliosis with
And medicine, but for the Chinese herbal medicine extract of the present invention, in prior art, there is no any disclosure or enlightenment.
Whether the health of hair is considered as the whether healthy sign of painstaking effort by the traditional Chinese medical science.It is taken as that the imbalance of painstaking effort function for
The impact of hair is very huge, therefore have " though beard and hair eyebrow all hairs, and the main the five internal organs of institute are different, it is, in the heart, to report fire of moxibustion to send out "
Saying, although for this kind of phenomenon has described in ancient books but due to having no rigorous scientific research and excess syndrome at that time therefore logical
Often use a kind of medicament for nourishing painstaking effort, such as Radix Polygoni Multiflori, Fructus Ligustri Lucidi etc. for the promotion growth and experience succession of hair,
Then it has been gradually added into excess syndrome with scientific progress to enrich the intension of Chinese Traditional Medicine.Although it is aforementioned point out ancient books in record
For the medical material for promoting natural on-off cycles of hair growth, and also it is no lack of in Chinese herbal medicine and there are many medical materials that can promote natural on-off cycles of hair growth, but must
With appropriate proportioning, the effectiveness of Chinese herbal medicine could must be more lifted.
The content of the invention
For the problem in the presence of prior art, the invention provides one kind can promote hair growth promoting, hair color and improve head
The Chinese herbal medicine extract of scurf, the extract are obtained by extraction from the crude drug including following Chinese herbal medicine：Radix Ginseng, the West
Ginseng, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei, Semen Cuscutae, Radix Polygalae, Herba Menthae, Herba Moslae, Fructus Ligustri Lucidi, Cortex Fraxini, Flos Caryophylli, Rhizoma Zingiberiss, Fructus Alpiniae Oxyphyllae, the Rhizoma Atractylodis Macrocephalae, Fructus Tribuli,
Herba Portulacae, Semen Armeniacae Amarum, Fructus Rubi, Semen Sesami Nigrum, Semen Platycladi, Fructus Aurantii, Pericarpium Citri Reticulatae, Herba Spirodelae, Radix Achyranthis Bidentatae, Radix Et Rhizoma Nardostachyos, Fructus Gleditsia, the Radix Astragali, Cortex Mori, perfume (or spice)
Attached, Poria, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Cnidii, Gao sheets, Cortex Cinnamomi, Radix Morindae Officinaliss, Radix Rubiae, Rhizoma Gastrodiae, Herba Dendrobii, Fructus Schisandrae Chinensis, Flos Magnoliae, Rhizoma Alismatis, king
Do not stay row, Fructus Corni, Herba Lophatheri, Fructus Jujubae, Semen Ziziphi Spinosae, Herba Cistanches, Radix Dipsaci, Radix Codonopsis, Semen Plantaginiss, Herba Cynomorii, Radix Ampelopsis, Herba Epimedii,
Cortex Lycii, Rhizoma Nelumbiniss and the Cortex Eucommiae；
Percetage by weight in crude drug shared by each taste Chinese medicine is 0.5wt% to 30wt%, and the total composition of each taste medicine is
100wt%, crude drug grind to form powder, and prepare described Chinese herbal medicine extract by any one in following method：
(1) crude drug for grinding to form powder accounts for 20wt%, accounts for dipropylene glycol (DPG, Dipropylene glycol)
3.6wt%, accounts for 5.2wt% with Isopropanediol (IPG, 1,2-Propylene Glycol), with Propylene Glycol (PG, Propylene
Glycol 4.8wt%) is accounted for, and 2.3wt% is accounted for butanediol (1,3BG, 1,3Butylene lycol), with Sorbitol
(Sorbitol) 3.5wt% is accounted for, and 4.2wt% is accounted for sorbeth -30 (Sorbeth-30), it is the crude drug, dipropylene glycol, different
Propylene Glycol, Propylene Glycol, butanediol, Sorbitol, each error allows 5% to the percentage by weight of sorbeth -3, is mended with water
To 100%；At 60 ± 5 DEG C, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(2) crude drug for grinding to form powder accounts for 20wt%, accounts for dipropylene glycol (DPG, Dipropylene glycol)
50wt%, the crude drug, each error allows 5% to the percentage by weight of dipropylene glycol, is mended to 100% with water；At 60 ± 5 DEG C
Under, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(3) crude drug for grinding to form powder accounts for 20wt%, accounts for Isopropanediol (IPG, 1,2-Propylene Glycol)
50wt%, the crude drug, the respective error of the percentage by weight of Isopropanediol allow 5%, are mended to 100% with water；At 60 ± 5 DEG C
Under, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(4) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Propylene Glycol (PG, Propylene Glycol),
The crude drug, each error allows 5% to the percentage by weight of Propylene Glycol, is mended to 100% with water；At 60 ± 5 DEG C, heating 1 ±
0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(5) crude drug for grinding to form powder accounts for 20wt%, accounts for butanediol (1,3BG, 1,3Butylene lycol)
50wt%, the crude drug, each error allows 5% to the percentage by weight of butanediol, is mended to 100% with water；At 60 ± 5 DEG C,
Heating 1 ± 0.5 hour, filters, obtains final product Chinese herbal medicine extract；Or
(6) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Sorbitol (Sorbitol), the crude drug,
Each error allows 5% to the percentage by weight of Sorbitol, is mended to 100% with water；At 60 ± 5 DEG C, heat 1 ± 0.5 hour,
Filter, obtain final product Chinese herbal medicine extract；Or
(7) crude drug for grinding to form powder accounts for 20wt%, and sorbeth -30 (Sorbeth-30) accounts for 50wt%, the original
Expect medicine, each error allows 5% to the percentage by weight of sorbeth -30, mended to 100% with water；At 60 ± 5 DEG C, heating 1
± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(8) crude drug for grinding to form powder accounts for 20wt%, with the ethanol that the concentration that percetage by weight is 80wt% is 58%
Mutually mix；At 83.4 ± 5 DEG C, heat 1 ± 0.5 hour, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase
Subtract and make summation be 100%, filter, obtain final product Chinese herbal medicine extract；Or
(9) crude drug for grinding to form powder accounts for 20wt%, with the ethanol that the concentration that percetage by weight is 80wt% is 58%
Mutually mix, soak 30 ± 5 days, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase and decrease and make the summation be
100%, filter, obtain final product Chinese herbal medicine extract.
Using said herbal medicine composition by rational proportion, the extract for preparing has promotion cell activation to the present invention
And the function of hypertrophy, what which discharged answer educates the applicable scope of the leading factor includes：Activation hair follicle cell, for example, promote hair follicle
The growth of cell, hypertrophy hair, treatment of dandruff, treatment alopecia；Activation melanocyte, for example, promote the life of melanocyte
Long, light color hair dark colorization.Therefore the application in the medicine for processing above-mentioned condition is prepared, the scope of the present invention is also also belonged to.
Therefore, further, the present invention proposes described promotion hair growth promoting, hair color and improves the Chinese herbal medicine extract of the dandruff
Application in the medicine for promoting hair growth promoting is prepared.And
It is described to promote hair growth promoting, hair color and improve the Chinese herbal medicine extract of the dandruff in preparing and promoting hair blackening medicine
Application.And
It is described to promote hair growth promoting, hair color and improve the Chinese herbal medicine extract of the dandruff to improve in dandruff medicine preparing
Using.
Specific embodiment
Present disclosure, characteristic and embodiment are illustrated below, so that those skilled in the art have more to enter to the present invention
One step understands.
The present invention relates to a kind of promote hair growth promoting, hair color and improve the Chinese herbal medicine extract of the dandruff, including：
Radix Ginseng：The effect purpose of Radix Ginseng be soothe the nerves, stop palpitate with fear, thus extraction Radix Ginseng composition be used as medicine, to improve spiritual pressure
The alopecia factor that power causes.
Radix Panacis Quinquefolii：The effect purpose of Radix Panacis Quinquefolii is YIN nourishing and QI supplementing, and the mind calming and mentality promoting, convulsion, paroxysmal pain are antipyretic, therefore extraction west
The composition of Radix Panacis Quinquefolii is used as medicine, and improves the alopecia factor that stress causes.
Radix Polygoni Multiflori：The effect purpose of Radix Polygoni Multiflori is sent out for black moustache, therefore the composition of extraction Radix Polygoni Multiflori is used as medicine, and improves and degenerates what is caused
Poliosis factor.
Radix Et Rhizoma Rhei：The effect purpose of Radix Et Rhizoma Rhei is lower blood stasis, except cold and heat, breaks lump, therefore the composition of extraction Radix Et Rhizoma Rhei is used as medicine, with profit association
Effect is helped, improves the problem of hair.
Semen Cuscutae：Semen Cuscutae its effect purpose is for can be deficient to tonification helpful, therefore the composition of extraction Semen Cuscutae is used as medicine, and changes
It is apt to because of deficient caused hair factor.
Radix Polygalae：The effect purpose of Radix Polygalae is the problem that can improve wind syndrome of head, therefore the composition of extraction Radix Polygalae is used as medicine, and improves wind syndrome of head and draws
The hair factor for rising.
Herba Menthae：The effect purpose of Herba Menthae to improve cold wind syndrome of head, refresh oneself except the problem of wind heat, therefore extraction Herba Menthae into
Medicine is divided into, is improved because of the factor of hair caused by wind heat.
Herba Moslae：The effect purpose of Herba Moslae is to improve the rare problem of children hair, therefore the composition of extraction Herba Moslae is used as medicine, and changes
The factor that kind natural on-off cycles of hair growth is stagnated.
Fructus Ligustri Lucidi：The effect purpose of Fructus Ligustri Lucidi is black problem of can turning white again, therefore the composition of extraction Fructus Ligustri Lucidi is used as medicine, and improves
The problem turned white.
Cortex Fraxini：The effect purpose of Cortex Fraxini is to improve the problem turned white, therefore the composition of extraction Cortex Fraxini is used as medicine, what improvement was turned white
Problem.
Flos Caryophylli：The effect purpose of Flos Caryophylli be can be coated in the hair follicle for take out poliosis in can give birth to the problem of hair color, therefore extraction fourth
Fragrant composition is used as medicine, and improves hair and degenerates and promote the reducing/regenerating hair color factor.
Rhizoma Zingiberiss：The effect purpose of Rhizoma Zingiberiss is gas of dispeling cold, and controls hemiplegia, therefore the composition of extraction Rhizoma Zingiberiss is used as medicine, to help improve head
Question is inscribed.
Fructus Alpiniae Oxyphyllae：The effect purpose of Fructus Alpiniae Oxyphyllae be qi-restoratives regulating QI, benefiting vital QI for tranquillizing, thus extraction Fructus Alpiniae Oxyphyllae composition be used as medicine, with
Help improve hair problem.
The Rhizoma Atractylodis Macrocephalae：The effect purpose of the Rhizoma Atractylodis Macrocephalae is dehumidifying qi invigorating functions, therefore the composition of the extraction Rhizoma Atractylodis Macrocephalae is used as medicine, to help improve hair
Effect.
Fructus Tribuli：The effect purpose of Fructus Tribuli is to improve children's head sore, therefore the composition of extraction Fructus Tribuli is used as medicine, and improves head sore and has an itch
Caused hair problem.
Herba Portulacae：The effect purpose of Herba Portulacae is bald in vain to improve exudative dermatitis, and the detumescence of scattered blood, therefore the composition of extraction Herba Portulacae
It is used as medicine, hair problem is improved with profit.
Semen Armeniacae Amarum：The effect purpose of Semen Armeniacae Amarum is all wind of head and the problem for improving skin ulcer Carbuncle scabies, therefore extracts the composition of Semen Armeniacae Amarum
It is used as medicine, helps improve hair problem.
Fructus Rubi：The effect purpose of Fructus Rubi sends out not white for order, therefore the composition of extraction Fructus Rubi is used as medicine, and assists order to send out not white
Problem.
Semen Sesami Nigrum：The effect purpose of Semen Sesami Nigrum falls to improve head alopecia, therefore the composition of extraction Semen Sesami Nigrum is used as medicine, and helps improve
Hair problem.
Semen Platycladi：The effect purpose of Semen Platycladi for improve palpitation with fear and can QI invigorating, therefore extraction Semen Platycladi composition be used as medicine, help
Improve the problem of hair.
Fructus Aurantii：The effect purpose of Fructus Aurantii is to improve skin pruritus due to wind pathogen, therefore the composition of extraction Fructus Aurantii is used as medicine, and assists because pruritus due to wind pathogen is drawn
The hair problem for rising.
Pericarpium Citri Reticulatae：The effect purpose of Pericarpium Citri Reticulatae is the therapeutic method to keep the adverse QI flowing downwards of deodorizing, qi-regulating removing obstruction for relieving pain, therefore the composition of extraction Pericarpium Citri Reticulatae is used as medicine, to manage
Gas eliminating stagnation and improve the problem of hair.
Herba Spirodelae：The effect purpose of Herba Spirodelae for can long beard and hair, therefore extraction Herba Spirodelae composition be used as medicine, help growth promoting beard and hair.
Radix Achyranthis Bidentatae：Hair is white to improve for the effect purpose of Radix Achyranthis Bidentatae, therefore the composition of extraction Radix Achyranthis Bidentatae is used as medicine, and helps improve hair
In vain.
Radix Et Rhizoma Nardostachyos：The effect purpose of Radix Et Rhizoma Nardostachyos is regulating the flow of QI to alleviate depression, therefore the composition of extraction Radix Et Rhizoma Nardostachyos is used as medicine, and with sharp synergism, changes
Kind hair problem.
Fructus Gleditsia：The effect purpose of Fructus Gleditsia is to eliminate wind syndrome of head, therefore the composition of extraction Fructus Gleditsia is used as medicine, and assist to improve hair and ask
Topic.
The Radix Astragali：The effect purpose of the Radix Astragali is beneficial fur, therefore the composition of the extraction Radix Astragali is used as medicine, and helps improve hair problem.
Cortex Mori：The effect purpose of Cortex Mori is tonify deficiency benefit health, and improves that hair is withered, thus extraction Cortex Mori into being divided into
Medicine, with sharp synergism, improves the problem of hair.
Rhizoma Cyperi：The effect purpose of Rhizoma Cyperi to make us the long man of QI invigorating and improving polarization wind syndrome of head, therefore extraction Rhizoma Cyperi into being divided into
Medicine, helps and long man.
Poria：The effect purpose of Poria be nourishing YIN QI invigorating, beneficial skin, thus extraction Poria composition be used as medicine, help improve head
The problem sent out.
Radix Ophiopogonis：The effect purpose of Radix Ophiopogonis is the heating of row disease, manic, headache when improving, therefore the composition for extracting Radix Ophiopogonis is used as medicine, with
Profit helps improve hair problem.
Rhizoma Polygonati：The effect purpose of Rhizoma Polygonati is the problem for mending five kinds of strain and seven kinds of impairment, therefore the composition of extraction Rhizoma Polygonati is used as medicine, and improves head with profit
Question is inscribed.
Fructus Cnidii：The effect purpose of Fructus Cnidii be except stagnated QI, therefore extraction Fructus Cnidii composition be used as medicine, hair is improved with profit and is asked
Topic.
Gao sheets：The effect purpose of Gao sheets is to treat arthralgia pain, therefore the composition of extraction Gao sheets is used as medicine, and with sharp synergism, improves head
Question is inscribed.
Cortex Cinnamomi：The effect purpose of Cortex Cinnamomi is to treat because of the problem of the headache caused by coldheat complex, thus extraction Cortex Cinnamomi into being divided into
Medicine, improves hair problem with profit.
Radix Morindae Officinaliss：The effect purpose of Radix Morindae Officinaliss can help to treat head urticaria to improve a wind cutting, thus extraction Radix Morindae Officinaliss into
Medicine is divided into, hair problem is improved with profit.
Radix Rubiae：The effect purpose of Radix Rubiae is to improve cold-damp numbness, promoting blood circulation promoting the circulation of blood, qualcomm meridian, therefore the composition of extraction Radix Rubiae is used as medicine,
With sharp synergism, and improve the problem of hair.
Rhizoma Gastrodiae：The effect purpose of Rhizoma Gastrodiae is to improve rheumatic arthralgia and treating dizziness and headache, therefore the composition of extraction Rhizoma Gastrodiae is used as medicine, with
Profit helps improve hair problem.
Herba Dendrobii：The effect purpose of Herba Dendrobii is to improve by skin wind and cold arthralgia pain, therefore the composition of extraction Herba Dendrobii is used as medicine, with profit improvement
Hair problem.
Fructus Schisandrae Chinensis：The effect purpose of Fructus Schisandrae Chinensis be QI invigorating, heat extraction, thus extraction Fructus Schisandrae Chinensis composition be used as medicine, with profit assistance change
Kind hair problem.
Flos Magnoliae：The effect purpose of Flos Magnoliae is to improve wind syndrome of head headache, therefore the composition of extraction Flos Magnoliae is used as medicine, with sharp synergism,
Improve the problem of hair.
Rhizoma Alismatis：The effect purpose of Rhizoma Alismatis is to improve anemofrigid-damp arthralgia, dizzy and tonifying deficiency, therefore the composition of extraction Rhizoma Alismatis is used as medicine,
Hair problem is helped improve with profit.
Semen Vaccariae：The effect purpose of Semen Vaccariae to improve wind syndrome of head, the dandruff, therefore extraction Semen Vaccariae into being divided into
Medicine, improves hair problem with profit.
Fructus Corni：To treat wind syndrome of head, except wind cutting gas one by one, therefore the composition of extraction Fructus Corni is used as medicine the effect purpose of Fructus Corni,
The problem of hair is helped improve with profit.
Herba Lophatheri：The effect purpose of Herba Lophatheri is refrigeration function, therefore the composition of extraction Herba Lophatheri is used as medicine, and assists to make with profit
With improving hair problem.
Fructus Jujubae：The effect purpose of Fructus Jujubae is and negative and positive, and adjusts the effect of Rong Wei, therefore the composition of extraction Fructus Jujubae is used as medicine, with profit
Improve hair problem.
Semen Ziziphi Spinosae：The effect purpose of Semen Ziziphi Spinosae is to improve sweating due to debility excessive thirst, therefore the composition of extraction Semen Ziziphi Spinosae is used as medicine, with profit improvement
Hair problem.
Herba Cistanches：The effect purpose of Herba Cistanches is to treat five kinds of strain and seven kinds of impairment, therefore the composition of extraction Herba Cistanches is used as medicine, and assists to make with profit
With improving hair problem.
Radix Dipsaci：The effect purpose of Radix Dipsaci is various temperature poison of dispelling, promoting blood circulation, therefore the composition of extraction Radix Dipsaci is used as medicine, and is changed with profit
Kind hair problem.
Radix Codonopsis：The effect purpose of Radix Codonopsis is invigorating the spleen and replenishing QI, therefore the composition of extraction Radix Codonopsis is used as medicine, and with sharp synergism, changes
Kind hair problem.
Semen Plantaginiss：The effect purpose of Semen Plantaginiss is wind-dispelling poison, and except arthralgia chiefly caused by damp pathogen, therefore the composition of extraction Semen Plantaginiss is used as medicine, with profit association
Effect is helped, improves hair problem.
Herba Cynomorii：The effect purpose of Herba Cynomorii is Gan Wenbuyin, beneficial essence Xing Yang, therefore the composition of extraction Herba Cynomorii is used as medicine, with profit assistance
Effect, improves hair problem.
Radix Ampelopsis：The effect purpose of Radix Ampelopsis be eliminating stagnation gas, pain relieving heat extraction, thus extraction Radix Ampelopsis composition be used as medicine, with profit assist make
With improving hair problem.
Herba Epimedii：The effect purpose of Herba Epimedii is to improve all wind and cold dampnesss, therefore the composition of extraction Herba Epimedii is used as medicine, with profit
Synergism, improves hair problem.
Cortex Lycii：The effect purpose of Cortex Lycii is to help except rheumatism numbness, therefore the composition of extraction Cortex Lycii is used as medicine, and helps change
The problem of kind hair.
Rhizoma Nelumbiniss：The effect purpose of Rhizoma Nelumbiniss for can scattered blood stasis, therefore extraction Rhizoma Nelumbiniss composition be used as medicine, with sharp synergism, change
Kind hair problem.
The Cortex Eucommiae：The effect purpose of the Cortex Eucommiae is invigorating the spleen and replenishing QI, therefore the composition of the extraction Cortex Eucommiae is used as medicine, and with sharp synergism, changes
Kind hair problem.
Percetage by weight in crude drug shared by each taste Chinese medicine is 0.5wt% to 30wt%, and the total composition of each taste medicine is
100wt%, crude drug grind to form powder, and prepare described Chinese herbal medicine extract by any one in following method：
(1) crude drug for grinding to form powder accounts for 20wt%, accounts for dipropylene glycol (DPG, Dipropylene glycol)
3.6wt%, accounts for 5.2wt% with Isopropanediol (IPG, 1,2-Propylene Glycol), with Propylene Glycol (PG, Propylene
Glycol 4.8wt%) is accounted for, and 2.3wt% is accounted for butanediol (1,3BG, 1,3Butylene lycol), with Sorbitol
(Sorbitol) 3.5wt% is accounted for, and 4.2wt% is accounted for sorbeth -30 (Sorbeth-30), it is the crude drug, dipropylene glycol, different
Propylene Glycol, Propylene Glycol, butanediol, Sorbitol, each error allows 5wt% to the percentage by weight of sorbeth -3, with water
Mend to 100%；At 60 ± 5 DEG C, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(2) crude drug for grinding to form powder accounts for 20wt%, accounts for dipropylene glycol (DPG, Dipropylene glycol)
50wt%, the crude drug, each error allows 5% to the percentage by weight of dipropylene glycol, is mended to 100% with water；At 60 ± 5 DEG C
Under, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(3) crude drug for grinding to form powder accounts for 20wt%, accounts for Isopropanediol (IPG, 1,2-Propylene Glycol)
50wt%, the crude drug, the respective error of the percentage by weight of Isopropanediol allow 5%, are mended to 100% with water；At 60 ± 5 DEG C
Under, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(4) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Propylene Glycol (PG, Propylene Glycol),
The crude drug, each error allows 5% to the percentage by weight of Propylene Glycol, is mended to 100% with water；At 60 ± 5 DEG C, heating 1 ±
0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(5) crude drug for grinding to form powder accounts for 20wt%, accounts for butanediol (1,3BG, 1,3Butylene lycol)
50wt%, the crude drug, each error allows 5% to the percentage by weight of butanediol, is mended to 100% with water；At 60 ± 5 DEG C,
Heating 1 ± 0.5 hour, filters, obtains final product Chinese herbal medicine extract；Or
(6) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Sorbitol (Sorbitol), the crude drug,
Each error allows 5% to the percentage by weight of Sorbitol, is mended to 100% with water；At 60 ± 5 DEG C, heat 1 ± 0.5 hour,
Filter, obtain final product Chinese herbal medicine extract；Or
(7) crude drug for grinding to form powder accounts for 20wt%, and sorbeth -30 (Sorbeth-30) accounts for 50wt%, the original
Expect medicine, each error allows 5% to the percentage by weight of sorbeth -30, mended to 100% with water；At 60 ± 5 DEG C, heating 1
± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(8) crude drug for grinding to form powder accounts for 20wt%, with the ethanol that the concentration that percetage by weight is 80wt% is 58%
Mutually mix；At 83.4 ± 5 DEG C, heat 1 ± 0.5 hour, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase
Subtract and make summation be 100%, filter, obtain final product Chinese herbal medicine extract；Or
(9) crude drug for grinding to form powder accounts for 20wt%, with the ethanol that the concentration that percetage by weight is 80wt% is 58%
Mutually mix, soak 30 ± 5 days, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase and decrease and make the summation be
100%, filter, obtain final product Chinese herbal medicine extract.
Preferably, the filtration described in aforementioned 1-9 kinds method, be with 1000 mesh more than careful filtration.
Above medical material its extract be can promote the growth of hair follicle cell, hypertrophy hair, treatment of dandruff, treatment alopecia and
Promote growth, the light color hair dark colorization of melanocyte, therefore preparation also belongs to this in the application of the medicine for processing above-mentioned condition
Within invention protection domain." hair follicle cell (follicle) " is that the bourse for existing and being surrounded on around root of hair is thin
Born of the same parents, with the function of controlling hair growth；When hair growth to regular period, the hair follicle of root of hair dwindles into rod by cylindric
During shape, hair follicle gradually atrophy, hair come off therewith, and after one section of resting stage, hair follicle cell is simultaneously enlivened, reconstructed hair follicles once again,
Breed regeneration new hair." alopecia (Alopecia) " comes off for hair of scalp is abnormal, its induction factor have hormonal disorder,
Disease generation, Inheritance, malnutrition, emotional factor, mental pressure, endocrine imbalance, receive treatment of cancer etc., lead
Cause abnormal alopecia.
" melanocyte (melanocyte) " is a kind of zooblast, is contained within melanin or its similar pigment,
Generally in epiderm skin with eyes tunica uvea (uvea of iris behind).Melanocyte homoiothermous, except energy
Manufacture melanin, can also manufacture the pigments such as some yellow, redness, and the melanocyte of poikilothermal animal is only capable of manufacturing single black
Element.The metabolism of melanocyte is if subjected to suppression and destruction, easily diseases induced.Except the colour system of skin, eyes and hair
Outside relevant with melanocyte, any speckle on melanotic nevus, freckle or skin, and have direct correlation with black cell.
" dandruff (dandruff) " is aging, peeling formation for the cutin cortex cell on scalp top layer, generally thin slice
Shape.Cornu cutaneum cell plastid proliferation rate is too fast right overhead, smegma is crossed Sheng, resides in the scurf Bacillus (Pityrosporumovale) hypertrophy ... of hair follicle
Deng can all produce excessive epidermis cell and be deposited in epidermal area.
Effect：
Refer to shown in adnexa one, adnexa one is three user point after the Chinese herbal medicine extract treatment using the present invention
The state do not tested in different time points.
Mr. A：Patient's alopecia for many years, hair floss and dilute, head oligotrichosis, using the Chinese herbal medicine of the present invention
Extract is treated, and head smears the Chinese herbal medicine extract of the present invention, and three times a day, at the top of 2 months back of medication, hair has growth
Phenomenon, three times a day, at the top of 4 months back of medication, rare hair gradually becomes dense.
Mr. B：Crown alopecia, it is existing for many years, hair floss and dilute, head oligotrichosis, using the medium-height grass of the present invention
Medicine extract is treated, and three times a day, at the top of 3 months back of medication, hair has growth phenomenon, three times a day, 5 months back of medication
The rare hair in top gradually becomes dense.
Mr. C：Crown alopecia, existing head is without hair.Treated using the Chinese herbal medicine extract of the present invention, head smears this
The Chinese herbal medicine extract of invention, three times a day, has many hairs to occur at the top of 3 first quarter moon back of medication.
Result above shows that the present invention has a significant effect.
Smeared on skin of head using the Chinese herbal medicine extract of the present invention, can be observed to promote hair growth and head
The effect that scurf is cured, therefore can illustrate that aforementioned extract has the function of activation hair follicle cell, and can be applicable to be manufactured into and have
Promote hair follicle cell growth and hypertrophy hair and treatment alopecia, cure the medical extract of the effects such as the dandruff.
Smeared on the skin of head surface that the hair because of aging bleaches using the Chinese herbal medicine extract of the present invention, it is considerable
Observe the phenomenon that the hair growth of poliosis reduction, black or dark color increases.Originally because aging occurs the work of dermal melanin cell
Property reduce or dead, but original hair follicle cell still continuous action and grow poliosis, therefore can illustrate that extract of the present invention has
Activating skin melanocyte, and can be applicable to be manufactured into the work such as the growth of promotion melanocyte and light color hair dark colorization
Medical extract.
In brief, those skilled in the art will be understood that extract provided by the present invention can apply to, and activate hair
Bladder cell, for example, promote hair follicle cell growth, hypertrophy hair, treatment alopecia, treatment of dandruff；Activation melanocyte, for example
Promote the aspects such as growth, the light color hair dark colorization of melanocyte.So as to aforementioned extract processes aforementioned various shapes in preparation
Application in the medicine of condition, also in the covered category of the present invention.
Furthermore, though this case category Chinese herbal medicine association area invention, contained chemistry in inventor's understanding extract of the present invention
By associated mechanisms, composition, Economic and Trade Commission detect that composition therein, testing result at least include in finding herb extract kind of the invention
Following composition, these compositions, though its effect has no direct correlation with the patentability of the invention of this case Chinese herbal medicine attribute, are only explained
It is bright its be various chemical substances synthesis result, therefore every characteristic not with regard to its composition, be used as and further explaining, only sieve
Row are disclosed.
In sum, this case should meet patentability, above-mentioned cited example, only presently preferred embodiments of the present invention,
When can not with its limit the scope of the present invention.The impartial change made according to scope of the present invention patent and modification, all should be still
Remain within the scope of the patent.
Claims (4)
1. a kind of to promote hair growth promoting, hair color and improve the Chinese herbal medicine extract of the dandruff, the extract is from by following Chinese herbal medicine group
Into crude drug in be obtained by extraction：Radix Ginseng, Radix Panacis Quinquefolii, Radix Polygoni Multiflori, Radix Et Rhizoma Rhei, Semen Cuscutae, Radix Polygalae, Herba Menthae, Herba Moslae, Fructus Ligustri Lucidi,
It is Cortex Fraxini, Flos Caryophylli, Rhizoma Zingiberiss, Fructus Alpiniae Oxyphyllae, the Rhizoma Atractylodis Macrocephalae, Fructus Tribuli, Herba Portulacae, Semen Armeniacae Amarum, Fructus Rubi, Semen Sesami Nigrum, Semen Platycladi, Fructus Aurantii, Pericarpium Citri Reticulatae, floating
Duckweed, Radix Achyranthis Bidentatae, Radix Et Rhizoma Nardostachyos, Fructus Gleditsia, the Radix Astragali, Cortex Mori, Rhizoma Cyperi, Poria, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Cnidii, Gao sheets, Cortex Cinnamomi, Radix Morindae Officinaliss, madder
Grass, Rhizoma Gastrodiae, Herba Dendrobii, Fructus Schisandrae Chinensis, Flos Magnoliae, Rhizoma Alismatis, Semen Vaccariae, Fructus Corni, Herba Lophatheri, Fructus Jujubae, Semen Ziziphi Spinosae, Herba Cistanches, Radix Dipsaci,
Radix Codonopsis, Semen Plantaginiss, Herba Cynomorii, Radix Ampelopsis, Herba Epimedii, Cortex Lycii, Rhizoma Nelumbiniss and the Cortex Eucommiae；
Percetage by weight in crude drug shared by each taste Chinese medicine is 0.5wt% to 30wt%, and the total composition of each taste medicine is
100wt%, crude drug grind to form powder, and prepare described Chinese herbal medicine extract by any one in following method：
(1) crude drug for grinding to form powder accounts for 20wt%, accounts for dipropylene glycol (DPG, Dipropylene glycol)
3.6wt%, accounts for 5.2wt% with Isopropanediol (IPG, 1,2-Propylene Glycol), with Propylene Glycol (PG, Propylene
Glycol 4.8wt%) is accounted for, and 2.3wt% is accounted for butanediol (1,3BG, 1,3Butylene lycol), with Sorbitol
(Sorbitol) 3.5wt% is accounted for, and 4.2wt% is accounted for sorbeth -30 (Sorbeth-30), it is the crude drug, dipropylene glycol, different
Propylene Glycol, Propylene Glycol, butanediol, Sorbitol, each error allows 5% to the percentage by weight of sorbeth -3, is mended with water
To 100%；At 60 ± 5 DEG C, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(2) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with dipropylene glycol (DPG, Dipropylene glycol),
The crude drug, each error allows 5% to the percentage by weight of dipropylene glycol, is mended to 100% with water；At 60 ± 5 DEG C, heating 1
± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(3) crude drug for grinding to form powder accounts for 20wt%, accounts for Isopropanediol (IPG, 1,2-Propylene Glycol)
50wt%, the crude drug, the respective error of the percentage by weight of Isopropanediol allow 5%, are mended to 100% with water；At 60 ± 5 DEG C
Under, heat 1 ± 0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(4) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Propylene Glycol (PG, Propylene Glycol), the original
Expect medicine, each error allows 5% to the percentage by weight of Propylene Glycol, mended to 100% with water；At 60 ± 5 DEG C, heating 1 ± 0.5 is little
When, filter, obtain final product Chinese herbal medicine extract；Or
(5) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with butanediol (1,3BG, 1,3Butylene lycol),
The crude drug, each error allows 5% to the percentage by weight of butanediol, is mended to 100% with water；At 60 ± 5 DEG C, heating 1 ±
0.5 hour, filter, obtain final product Chinese herbal medicine extract；Or
(6) crude drug for grinding to form powder accounts for 20wt%, accounts for 50wt% with Sorbitol (Sorbitol), the crude drug, Pyrusussuriensiss
Each error allows 5% to the percentage by weight of sugar alcohol, is mended to 100% with water；At 60 ± 5 DEG C, heat 1 ± 0.5 hour, mistake
Filter, obtains final product Chinese herbal medicine extract；Or
(7) crude drug for grinding to form powder accounts for 20wt%, and sorbeth -30 (Sorbeth-30) accounts for 50wt%, the crude drug,
Each error allows 5% to the percentage by weight of sorbeth -30, is mended to 100% with water；At 60 ± 5 DEG C, heating 1 ± 0.5
Hour, filter, obtain final product Chinese herbal medicine extract；Or
(8) crude drug for grinding to form powder accounts for 20wt%, mutually mixes with the ethanol that the concentration that percetage by weight is 80wt% is 58%；
At 83.4 ± 5 DEG C, heat 1 ± 0.5 hour, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase and decrease and
Make summation be 100%, filter, obtain final product Chinese herbal medicine extract；Or
(9) crude drug for grinding to form powder accounts for 20wt%, mutually mixes with the ethanol that the concentration that percetage by weight is 80wt% is 58%,
Immersion 30 ± 5 days, crude drug, each error allows 5% to the percentage by weight of ethanol, mutually increase and decrease and make summation for 100%, mistake
Filter, obtains final product Chinese herbal medicine extract.
2. promoting hair growth promoting, hair color and improving the Chinese herbal medicine extract of the dandruff described in claim 1 promotes hair growth promoting preparing
Application in medicine.
3. promoting hair growth promoting, hair color and improving the Chinese herbal medicine extract of the dandruff described in claim 1 promotes hair to become preparing
Application in black powder thing.
4. promoting hair growth promoting, hair color and improving the Chinese herbal medicine extract of the dandruff described in claim 1 improves the dandruff in preparation
Application in medicine.
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| CN104688616B (en) * | 2014-09-25 | 2018-01-12 | 朱绍华 | White hair is contaminated to black pure plant hair colouring methods and hair dyeing product |
| CN104706557A (en) * | 2015-03-31 | 2015-06-17 | 深圳市诗碧曼科技有限公司 | Hair conditioner essence |
| CN105030581A (en) * | 2015-06-29 | 2015-11-11 | 柳州弘天科技有限公司 | Traditional Chinese medicinal shampoo |
| CN105231739B (en) * | 2015-09-25 | 2016-08-17 | 邱君杰 | A kind of medicated pillow of blacking hair and nourishing face |
| CN105311345A (en) * | 2015-11-27 | 2016-02-10 | 劳冠阳 | Medicine for removing dandruff |
| CN107007528A (en) * | 2017-04-07 | 2017-08-04 | 陈海燕 | A kind of hair growth liquor and preparation method thereof |
| CN107184034A (en) * | 2017-06-07 | 2017-09-22 | 宋东宁 | A kind of health care pillow and pillow for blackening hair |
| CN107158151A (en) * | 2017-07-20 | 2017-09-15 | 广州市粤波医院（有限合伙） | It is a kind of to treat Chinese medicine preparation of white hair and preparation method thereof |
| CN107854401A (en) * | 2017-12-18 | 2018-03-30 | 深圳市诗碧曼科技有限公司 | A kind of hairdressing Essence |
| CN108066274B (en) * | 2018-01-25 | 2021-03-30 | 深圳市大鳄生物科技股份有限公司 | Hair blackening compound and preparation method and application thereof |
| CN108324846A (en) * | 2018-03-28 | 2018-07-27 | 霸州市巨隆生物科技有限公司 | A kind of Chinese medicine composition of hair care and nourishing |
| CN112999280B (en) * | 2021-02-08 | 2022-04-15 | 华南农业大学 | Pericarpium citri reticulatae extracting solution, preparation method and application thereof |
| CN115708796A (en) * | 2022-11-30 | 2023-02-24 | 广州楚颜化妆品有限公司 | Herbal composition for changing white hair into black hair and preparation method thereof |
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| TWI368515B (en) * | 2006-06-16 | 2012-07-21 | Brion Res Inst Of Taiwan | Medical herb composition for promoting the growth of mammal's hairs and the manufacturing method thereof |
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