CN104042855B - A kind of Chinese medicine composition for treating spur and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating spur and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating spur, is made up of Smilacina japonica, careless chinaroot greenbrier, paniculate swallowwort, Cocculus trilobus, levisticum, bark of ash, Aconitum Szechenyianum Gay and the taste bulk drug of radix glycyrrhizae eight.In addition, the invention also discloses the preparation method of the Chinese medicine composition.The present invention has the effect of activating blood circulation and reducing swelling, wind-expelling pain-stopping using Smilacina japonica as monarch drug in a prescription；Paniculate swallowwort and bark of ash are ministerial drug, and paniculate swallowwort has the effect of clearing damp removing toxic substances, sedation-analgesia, and bark of ash has the effect of wind-damp dispelling, clearing away damp-heat, stopping numbness pain；Careless chinaroot greenbrier, Aconitum Szechenyianum Gay, Cocculus trilobus and levisticum are adjutant, careless chinaroot greenbrier dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, Aconitum Szechenyianum Gay promoting blood circulation, dispeling wind and dehumidification, alleviating pain and detumescence, root of fangji wind-expelling pain-stopping, levisticum expelling wind and eliminating dampness, eliminating cold to stop pain；Radix glycyrrhizae has the effect of controlling vital organs of the human body fever and chills perverse trend, hard muscles and bones, slow healthy tendency to make medicine.All medicines share, promoting blood circulation and removing obstruction in channels, wind-expelling pain-stopping is focused on, for osteoproliferation, rheumatic arthritis, rheumatalgia has special efficacy.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine composition for treating spur and preparation method thereof.
Background technology
Spur is being commonly called as osteoproliferation, also known as bone wart, is common disease, the frequently-occurring disease of person in middle and old age.With advancing age,
The cartilage in joint is gradually degenerated, and the elasticity reduction of cell, Bones and joints are unconsciously being worn, and especially activity is larger
Neck, waist, knee joint, heel, the articular cartilage of damage are difficult to repair when no blood vessel supplies nutrition, at this moment in articular cartilage
Peripheral blood recycle ratio it is more vigorous, just occur compensatory cartilage increase, this is the predecessor of osteoproliferation.Increase over time
Raw cartilage is again by calcification, and here it is osteoproliferation.It is a kind of natural aging phenomenon, general long spur means that the ridge of this person
Vertebra enters the ageing step.
Spur is not the patent of elder person, because work kenel changes, the necessary sitting of many people, long station, if adding appearance
Gesture is incorrect, it is easy to which cartilage ages phenomenon gently just occurs for the age, and induces the generation of spur.Spur mostly occurs in cervical vertebra
And lumbar vertebrae, wrist, joint, heel can also occur.Spur can cause sciatica, disc herniation, spinal canal stenosis, degeneration
Property arthritis, can cause when serious people can not walk and activity, had a strong impact on the quality of life of people.Doctor trained in Western medicine is sick still to this at present
Without effective medicine, the medicine of some antipyretic-antalgics can be taken frequently with anti symptom treatment, during such as pain；When numb, B races can be selected
Vitamin medicaments；Arthroncus has hydrops, and person can give the local extraction therapy such as hydrops or partial closure.But it facts have proved this
A little treatment methods are undesirable and cure the symptoms, not the disease, and the state of an illness easily recurs.Other ultraviolet therapy, massage, traction, acupuncture, massage,
It is simply interim to eliminate local oedema and inflammation, spur treatment is tightly helped out.
The traditional Chinese medical science thinks that spur is that channels and collaterals block caused by qi depression to blood stasis, wind-cold damp pathogen.Cold-evil stagnates spasm, and damp evil adhesive aggregation is not
To change, cause the passages through which vital energy circulates such as waist-leg to be obstructed, QI-blood circulation is not smooth or falls servant's wound, damages passages through which vital energy circulates qi and blood, or because prolonged illness QI-blood circulation is not smooth,
Cause meridian qi and blood retardance obstructed and pathogenic.
The content of the invention
The technical problems to be solved by the invention are to be directed to above-mentioned the deficiencies in the prior art, there is provided one kind is for hyperostosis
It is raw, rheumatic arthritis, the Chinese medicine composition of the specific treatment spur of rheumatalgia.The Chinese medicine composition using Smilacina japonica as monarch drug in a prescription,
Paniculate swallowwort and bark of ash are ministerial drug, and careless chinaroot greenbrier, Aconitum Szechenyianum Gay, Cocculus trilobus and levisticum are adjutant, and radix glycyrrhizae all medicines share, focuses on to make medicine
Promoting blood circulation and removing obstruction in channels, wind-expelling pain-stopping, for osteoproliferation, rheumatic arthritis, rheumatalgia has special efficacy.
In order to solve the above technical problems, the technical solution adopted by the present invention is：A kind of Chinese medicine composition for treating spur, its
It is characterised by, is made up of the bulk drug of following parts by weight：80-120 parts of Smilacina japonica, careless 100-140 parts of chinaroot greenbrier, paniculate swallowwort 140-
180 parts, 90-120 parts of Cocculus trilobus, 45-65 parts of levisticum, 45-65 parts of bark of ash, 5-15 parts of Aconitum Szechenyianum Gay, 45-65 parts of radix glycyrrhizae.
A kind of above-mentioned Chinese medicine composition for treating spur, is made up of the bulk drug of following parts by weight：Smilacina japonica 90-110
Part, careless 110-130 parts of chinaroot greenbrier, 150-170 parts of paniculate swallowwort, 100-110 parts of Cocculus trilobus, 50-60 parts of levisticum, bark of ash 50-60
Part, 8-12 parts of Aconitum Szechenyianum Gay, 50-60 parts of radix glycyrrhizae.
A kind of above-mentioned Chinese medicine composition for treating spur, is made up of the bulk drug of following parts by weight：100 parts of Smilacina japonica, grass
120 parts of chinaroot greenbrier, 159.75 parts of paniculate swallowwort, 106.5 parts of Cocculus trilobus, 53.25 parts of levisticum, 53.25 parts of bark of ash, 10 parts of Aconitum Szechenyianum Gay are sweet
53.25 parts of grass.
In addition, present invention also offers a kind of method for preparing above-mentioned Chinese medicine composition, it is characterised in that this method includes
Following steps：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 3~4, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, tablet, capsule or pill is made after mixing according to a conventional method.
The parts by weight can be gram, two, jin, the weight metering unit such as kilogram, ton.
Smilacina japonica：Nature and flavor " sweetness and bitterness temperature, nontoxic ", micro-pungent temperature, Return liver spleen, kidney channel, fill blood, strengthen the bone, wind-damp dispelling, only numbness
Bitterly, for treating internal lesion caused by overexertion, migraine and general headache, traumatic injury, arthralgia pain due to rheumatism, nameless gall.
Careless chinaroot greenbrier：It is sweet, slight bitter, puckery, put down.Return liver and kidney channel.Dampness removing removes turbid, wind expelling stagnation removing, detoxifies and dissipates the stasis of blood.
Paniculate swallowwort：It is pungent, temperature.Return liver, stomach.Wind-dispelling, dampness elimination, analgesic are antipruritic.For arthralgia pain due to rheumatism, turgor of having a stomachache, tooth
Bitterly, pain in the back, the pain of injury caused by falling and tumbling, rubella, eczema.
Cocculus trilobus：Dispelling wind and eliminating dampness, clearing and activating the channels and collaterals, removing toxicity for detumescence.Arthralgia pain due to rheumatism is cured mainly, oedema, urine leaching pain, amenorrhoea, is fallen
Beat damage, abscess of throat, sore swollen toxin, eczema, venomous snake bite.
Levisticum：It is pungent, bitter, tepor.Return kidney, bladder warp.Dispelling wind and eliminating dampness, numbness relieving and pain relieving.For wind-cold-dampness arthralgia, lumbocrural pain,
Few the moon volt wind headache, chill hold wet headache under the arm.
Bark of ash：It is pungent, it is bitter, put down.Return stomach, liver, gallbladder channel.Wind-damp dispelling, clearing away damp-heat, stopping numbness pain, reducing the asthenic fever.For arthralgia pain due to rheumatism,
Apoplexy and hemiplegia, muscle arteries and veins contraction, skeletal pain, jaundice with damp-heat pathogen, osteopyrexia and fever, infantile malnutrition generates heat.
Aconitum Szechenyianum Gay：Toil, heat.Promoting blood circulation, dispeling wind and dehumidification, alleviating pain and detumescence.Traumatic injury is controlled, rheumatic arthritis, is had a toothache,
Dyspeptic abdominalgia, dysmenorrhes, carbuncle swells, pernio.
Radix glycyrrhizae：It is sweet, put down.The thoughts of returning home, lung, spleen, stomach.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, reconcile all
Medicine.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, abirritant
It is thing toxicity, strong.
The present invention has advantages below compared with prior art：
1st, the present invention is prepared using pure Chinese medicine, is had no toxic side effect, and formula is simple, curative effect is reliable, preparation technology is simple, production
Cost is low, and for osteoproliferation, rheumatic arthritis, rheumatalgia has special efficacy.
2nd, Chinese medicine composition of the invention has the effect of activating blood circulation and reducing swelling, wind-expelling pain-stopping using Smilacina japonica as monarch drug in a prescription；Paniculate swallowwort and
Bark of ash is ministerial drug, and paniculate swallowwort has the effect of clearing damp removing toxic substances, sedation-analgesia, and bark of ash has wind-damp dispelling, clearing away damp-heat, the work(of stopping numbness pain
Effect；Careless chinaroot greenbrier, Aconitum Szechenyianum Gay, Cocculus trilobus and levisticum are adjutant, careless chinaroot greenbrier dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, Aconitum Szechenyianum Gay promoting blood circulation, are driven
Wind dehumidifies, alleviating pain and detumescence, root of fangji wind-expelling pain-stopping, levisticum expelling wind and eliminating dampness, eliminating cold to stop pain；Radix glycyrrhizae has to make medicine and controls the vital organs of the human body
The effect of fever and chills perverse trend, hard muscles and bones, slow healthy tendency.All medicines share, promoting blood circulation and removing obstruction in channels, wind-expelling pain-stopping is focused on, for osteoproliferation, rheumatism
Property arthritis, rheumatalgia have special efficacy.
Below by embodiment, technical scheme is described in further detail.
Embodiment
Embodiment 1
The Chinese medicine composition of the treatment spur of the present embodiment, is made up of following bulk drug：Smilacina japonica 80g, careless chinaroot greenbrier 100g, Xu
Long minister in ancient times 140g, Cocculus trilobus 90g, levisticum 45g, bark of ash 45g, Aconitum Szechenyianum Gay 5g, radix glycyrrhizae 45g.
The preparation method of the Chinese medicine composition of the treatment spur of the present embodiment is：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 3, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, pelletized after mixing, dry, be made 1000, produce the pill for the treatment of spur.
The usage and dosage of the pill of the treatment spur of the present embodiment：Once two grains, 3 times a day, warm water takes.
Embodiment 2
The Chinese medicine composition of the treatment spur of the present embodiment, is made up of following bulk drug：Smilacina japonica 120kg, careless chinaroot greenbrier
140kg, paniculate swallowwort 180kg, Cocculus trilobus 120kg, levisticum 65kg, bark of ash 65kg, Aconitum Szechenyianum Gay 15kg, radix glycyrrhizae 65kg.
The preparation method of the Chinese medicine composition of the treatment spur of the present embodiment is：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 4, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, tablet is made after mixing according to a conventional method, 1400000 altogether, produces the tablet for treating spur.
The usage and dosage of the tablet of the treatment spur of the present embodiment：One time 2,3 times a day, warm water takes.
Embodiment 3
The Chinese medicine composition of the treatment spur of the present embodiment, is made up of following bulk drug：Smilacina japonica 90g, careless chinaroot greenbrier 110g, Xu
Long minister in ancient times 150g, Cocculus trilobus 110g, levisticum 50g, bark of ash 60g, Aconitum Szechenyianum Gay 12g, radix glycyrrhizae 50g.
The preparation method of the Chinese medicine composition of the treatment spur of the present embodiment is：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 3.5, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, capsule is made after mixing according to a conventional method, 1100 altogether, produces the capsule for treating spur.
The usage and dosage of the capsule of the treatment spur of the present embodiment：Once two grains, 3 times a day, warm water takes.
Embodiment 4
The Chinese medicine composition of the treatment spur of the present embodiment, is made up of following bulk drug：Smilacina japonica 110g, careless chinaroot greenbrier 130g,
Paniculate swallowwort 170g, Cocculus trilobus 100g, levisticum 60g, bark of ash 50g, Aconitum Szechenyianum Gay 8g, radix glycyrrhizae 60g.
The preparation method of the Chinese medicine composition of the treatment spur of the present embodiment is：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 3.5, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, pelletized after mixing, dry, be made 1300, produce the pill for the treatment of spur.
The usage and dosage of the pill of the treatment spur of the present embodiment：Once two grains, 3 times a day, warm water takes.
Embodiment 5
The Chinese medicine composition of the treatment spur of the present embodiment, is made up of following bulk drug：Smilacina japonica 100g, careless chinaroot greenbrier 120g,
Paniculate swallowwort 159.75g, Cocculus trilobus 106.5g, levisticum 53.25g, bark of ash 53.25g, Aconitum Szechenyianum Gay 10g, radix glycyrrhizae 53.25g.
The preparation method of the Chinese medicine composition of the treatment spur of the present embodiment is：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: extraction is added water to cook after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water
For 8 times of bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, and second of amount of water is bark of ash, careless greenbrier
5 times of chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, with hydrochloric acid by the pH of decoction to be decocted before decocting every time
Value regulation 3.5, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
Step 3: the Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay that are ground into fine powder is added in step 1 into thick paste described in step 2
And levisticum, pelletized after mixing, dry, be made 1200, produce the pill for the treatment of spur.
The usage and dosage of the pill of the treatment spur of the present embodiment：Once two grains, 3 times a day, warm water takes.
Curative effect determinate standard：It is effective：Neck lumbar vertebrae local pain, dizziness, limbs pain and numb disappearance, knee joint locally ache
Pain disappears, and joint motion and walking with load function return to normal.Effectively：Above-mentioned each joint symptoms substantially mitigate.It is invalid：Respectively
Joint symptoms are without mitigating or have exacerbation.
General clinical data：Clinical observation case totally 280, treatment group 200, control group 80.Wherein, treatment group：
Take capsule 60 of the present invention；Take Tablets 60；Take pill 80 of the present invention.Control group 80 is taken often
Advise medicine bony spur tablet.Treatment group see the table below with control group curative effect comparative result：
The treatment group of table 1 and control group Comparison of therapeutic
As shown in table 1, clinical observation case 280 of the present invention, wherein treatment group 200, control group 80.Treatment group adopts
With capsule of the present invention, tablet and pill, wherein taking capsule 60, orally, once two grains, 3 times a day, warm water takes；Clothes
With 60, tablet, orally, one time 2,3 times a day, warm water takes；Pill 80 is taken, orally, once two grains, 3 times a day, temperature
Water delivery service；Control group is treated using conventional medicine bony spur tablet, the administration of conventional amount used shown in usage by specification.Treatment one month
Afterwards, compared with control group general curative effect, its result is for treatment group：Capsule 60 is taken in treatment group, effective 55, is accounted for
91.7%, effective 5,8.3% is accounted for, total effective rate 100%；60, tablet is taken in treatment group, effective 52, accounts for 86.7%,
Effective 8,13.3% is accounted for, total effective rate 100%；Pill 80 is taken in treatment group, effective 78, accounts for 97.5%, effective 2
Example, accounts for 2.5%, total effective rate 100%；Control group 80 takes bony spur tablet, effective 30, accounts for 37.5%, effective 30, accounts for
37.5%, invalid 20, account for 25%, total effective rate 75%, it is effective it is mostly be slight patient, and easily recurred after treating.Two groups
Comparing curative effect, there were significant differences.The present invention is using Smilacina japonica as monarch drug in a prescription, and paniculate swallowwort and bark of ash are ministerial drug, careless chinaroot greenbrier, Aconitum Szechenyianum Gay, Cocculus trilobus
It is adjutant with levisticum, radix glycyrrhizae all medicines share, focuses on promoting blood circulation and removing obstruction in channels, wind-expelling pain-stopping, for osteoproliferation, rheumatic is closed to make medicine
Section is scorching, and rheumatalgia has special efficacy, is adapted to marketing drugs to promote.
Model case
Case 1
Li Zequan, man, 65 years old, peasant, pain in the back 10 years, it is diagnosed as waist 2,3 through X-ray film making and bores osteoproliferation (spur), clothes
With guci pills, Fenbid, pain can be slowed down, but be recurred again after being discontinued, after use Chinese medicine composition of the present invention instead, took the same day, pain
Pain mitigates, and pain disappears substantially after one week, even served 2 months, and film making check, hyperplasia disappears, and functional rehabilitation is normal.
Case 2
Huang Chuanzhou, man, falls before 58 years old, 10 years from tree, causes the serious contusion of lumbar vertebrae to be allowed firmly with fracture, civilian hospital
Plank bed lies low rest two months, and takes Dieda Wan, but because other reasonses only lie low rest less than January, so far waist pain,
Rainy days is more very.Arrive hospital afterwards to make film inspection, it is seen that lumbar vertebrae 3,4 interbody spaces narrow, edge blurry, are diagnosed as lumbar vertebrae bone increasing
Raw (spur).Through taking Chinese medicine composition of the present invention 2 months, pain disappears；X pieces are checked, and gap broadens, clear-cut margin, made a definite diagnosis
Recovery from illness.
It is described above, only it is presently preferred embodiments of the present invention, any restrictions is not done to the present invention, it is every according to invention skill
Any simple modification, change and the equivalent structure change that art is substantially made to above example, still fall within the technology of the present invention
In the protection domain of scheme.
Claims (2)
1. a kind of Chinese medicine composition for treating spur, it is characterised in that be made up of the bulk drug of following parts by weight：100 parts of Smilacina japonica,
Careless 120 parts of chinaroot greenbrier, 159.75 parts of paniculate swallowwort, 106.5 parts of Cocculus trilobus, 53.25 parts of levisticum, 53.25 parts of bark of ash, 10 parts of Aconitum Szechenyianum Gay,
53.25 parts of radix glycyrrhizae.
A kind of 2. method for preparing Chinese medicine composition as claimed in claim 1, it is characterised in that this method comprises the following steps：
Step 1: Smilacina japonica, paniculate swallowwort, Aconitum Szechenyianum Gay and levisticum are ground into fine powder respectively；
Step 2: adding water to cook extraction after bark of ash, careless chinaroot greenbrier, Cocculus trilobus and radix glycyrrhizae are mixed twice, first time amount of water is the Qin
Macrophylla, careless chinaroot greenbrier, 8 times of Cocculus trilobus and radix glycyrrhizae gross mass, decocting time is 2 hours, second of amount of water be bark of ash, careless chinaroot greenbrier,
5 times of Cocculus trilobus and radix glycyrrhizae gross mass, decocting time are 2 hours, are adjusted the pH value for treating decoction liquor with hydrochloric acid before decocting every time
Section 3~4, merging filtrate after filtration, it is concentrated into 50 DEG C and measures the thick paste that relative density is 1.30；
The Smilacina japonica of fine powder, paniculate swallowwort, Aconitum Szechenyianum Gay and solely are ground into Step 3: being added into thick paste described in step 2 in step 1
It is living, tablet, capsule or pill is made after mixing according to a conventional method.
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