CN108159176A - A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of pill medicine for treating degenerative osteoarthropathy according to the understanding mechanism of Chinese traditional treatment degenerative osteoarthropathy, each component and its mass parts ratio of the drug are as follows：30~100g of Radix Angelicae Pubescentis, 120~360g of prepared rehmannia root, 60~120g of the root of Chinese clematis, 50~160g of Herba Epimedii, 150~300g of the root of bidentate achyranthes, 60~150g of rhizoma cibotii, 80~160g of Radix Salviae Miltiorrhizae, 150~300g of the rhizome of davallia, 100~160g of teasel root, 100~350g of yellow Stilbene, 60~100g of psoralea corylifolia, 100~160g of Ramulus Taxilli, 50~120g of Rhizoma Chuanxiong, 100~160g of Caulis Spatholobi, 80~160g of Radix Angelicae Sinensis, 15~70g of Radix Aucklandiae, 30~70g of frankincense, 50~250g of myrrh, 80~160g of peach kernel；Drug provided by the invention is a good Chinese prescription.

Description

A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating degenerative osteoarthropathy, especially It is the field of the pill medicine used for degenerative osteoarthropathy patient and preparation method thereof.

Background technology

It is shown according to document：Degenerative osteoarthropathy is also known as osteoarthritis, degenerative arthritis, senescent arthritis, hypertrophy Property arthritis, be a kind of retrogression pathological changes, be due to increasing age, obesity, strain, wound, joint birth defect, joint deformity etc. Articular cartilage degeneration damage, joint margins and subchondral bone reactive hyperplasia caused by factors.This disease is more common in person in middle and old age Crowd is apt to occur in weight-bearing joints and the more joint of activity（Such as, cervical vertebra, lumbar vertebrae, knee joint, hip joint etc.）.Excessively bear a heavy burden Or these joints are used, the generation that degeneration can be promoted to change.Clinical manifestation is arthralgia, tenderness, the deadlock slowly developed Firmly, arthroncus, limitation of activity and joint deformity etc..

Clinical manifestation：Cardinal symptom is arthralgia, is often rest pain, pain, activity a moment occurs after showing as rest Alleviate, but after hyperactivity, pain is aggravated again.Another symptom is anchylosis, and when often occurring getting up in the morning or daytime closes After section keeps certain position for a long time.It checks the swelling of affected joints visible joint, tenderness, there is abrasive feel or " clicker " when movable Sound, serious patient can have muscular atrophy and joint deformity.

So, it is art technology with regard to how to find a kind of Chinese medicine composition that can effectively treat degenerative osteoarthropathy The problem of personnel are urgently to be resolved.

Invention content

With the continuous development of China's traditional Chinese medicine, on treatment degenerative osteoarthropathy, people gradually appreciate The advantages of Chinese traditional treatment degenerative osteoarthropathy, and good effect, advantages, the needle such as quick, toxic side effect is small over the course for the treatment of To the present situation of existing western medical treatment degenerative osteoarthropathy, degeneration Bones and joints are treated the purpose of the invention is to provide a kind of The pill medicine of disease, to solve the problems, such as that degenerative osteoarthropathy patient gets well early.The drug is with common Chinese medicine For raw material, by selecting rational drug and mass parts ratio, above-mentioned degenerative osteoarthropathy can be effectively treated.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：A kind of degeneration bone for the treatment of is provided to close Save pill medicine of disease and preparation method thereof, which is characterized in that each component and mass parts of the drug are than as follows：

30~100g of Radix Angelicae Pubescentis, 120~360g of prepared rehmannia root, 60~120g of the root of Chinese clematis, 50~160g of Herba Epimedii, 150~300g of the root of bidentate achyranthes, 60~150g of rhizoma cibotii, 80~160g of Radix Salviae Miltiorrhizae, 150~300g of the rhizome of davallia, 100~160g of teasel root, 100~350g of yellow Stilbene, psoralea corylifolia 60~100g, 100~160g of Ramulus Taxilli, 50~120g of Rhizoma Chuanxiong, 100~160g of Caulis Spatholobi, 80~160g of Radix Angelicae Sinensis, Radix Aucklandiae 15~ 70g, 30~70g of frankincense, 50~250g of myrrh, 80~160g of peach kernel, auxiliary material：Appropriate starch.

A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof, which is characterized in that the drug it is each A component and mass parts are than as follows：

36~90g of Radix Angelicae Pubescentis, 135~320g of prepared rehmannia root, 70~105g of the root of Chinese clematis, 56~140g of Herba Epimedii, 180~260g of the root of bidentate achyranthes, 70~130g of rhizoma cibotii, 90~140g of Radix Salviae Miltiorrhizae, 180~260g of the rhizome of davallia, 115~140g of teasel root, 115~320g of yellow Stilbene, psoralea corylifolia 70~90g, 115~140g of Ramulus Taxilli, 56~105g of Rhizoma Chuanxiong, 115~140g of Caulis Spatholobi, 90~140g of Radix Angelicae Sinensis, Radix Aucklandiae 18~ 60g, 36~60g of frankincense, 56~220g of myrrh, 90~140g of peach kernel, auxiliary material：Appropriate starch.

A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof, which is characterized in that the drug it is each A component and mass parts are than as follows：

Radix Angelicae Pubescentis 80g, prepared rehmannia root 280g, root of Chinese clematis 95g, Herba Epimedii 120g, root of bidentate achyranthes 230g, rhizoma cibotii 118g, Radix Salviae Miltiorrhizae 120g, the rhizome of davallia 230g, teasel root 120g, yellow Stilbene 260g, psoralea corylifolia 80g, Ramulus Taxilli 120g, Rhizoma Chuanxiong 95g, Caulis Spatholobi 120g, Radix Angelicae Sinensis 120g, Radix Aucklandiae 52g, frankincense 52g, myrrh 200g, peach kernel 120g, auxiliary material：Appropriate starch.

A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof, which is characterized in that the method includes Following steps are prepared：

A, it in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and drying, is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese kmedicine bolus agent according to tradition after ground superfine myrrh object and starch sieving, is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, disinfection, sub-bottle dress Sealing.

A kind of pill medicine for treating degenerative osteoarthropathy and preparation method thereof, which is characterized in that the instructions of taking For：By the pill medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, dosage 5.5g/ times, and warm water is sent after meal Clothes, while pauciarticular heavy burden and excessive significantly activity should be subtracted）.15 days as a treatment course, 1~2 course for the treatment of of taking medicine, symptom Gradually mitigate.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Radix Angelicae Pubescentis, nature and flavor：Pungent, bitter, tepor has the effect of dispelling wind and eliminating dampness, numbness relieving and pain relieving, for treating wind-cold-dampness arthralgia, waist and knee pain Bitterly, few the moon volt wind headache；

Prepared rehmannia root, nature and flavor：Sweet, tepor has the effect of nourishing yin and supplementing blood, beneficial to spirit and marrow, for treating the deficiency of liver-yin and kidney-yin, waist and knee acid Soft, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizziness, tinnitus, Poliosis；

The root of Chinese clematis, nature and flavor：It is acrid flavour, salty, warm-natured, have wind-damp dispelling, degrading the channel the effect of, for treating arthralgia pain due to rheumatism, limbs Numbness, muscle arteries and veins contraction, joint stuffiness；

Herba Epimedii, nature and flavor：Xin Gan, temperature have the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, are not lifted for treating impotence, urine leaching The diseases such as drip, muscles and bones contraction urgency, hemiplegia, waist-leg weakness, arthralgia pain due to rheumatism, four limbs are meciless；

The root of bidentate achyranthes, nature and flavor：It is bitter, sour, mild-natured, there is filling liver kidney, strengthening the bones and muscles, invigorate blood circulation, draw enemy state（Fire) downlink, inducing diuresis for treating strangurtia it Effect, for treat soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhoea, postpartum abdominal pain due to blood stasis, note of the ancient Chinese lump in the abdomen, placenta retension, heat gonorrhea, Blood strangury, traumatic injury, Carbuncle swells dislikes sore, abscess of throat；

Rhizoma cibotii, nature and flavor：It is bitter, sweet, warm, have filling liver kidney, strong spinal column, wind-damp dispelling the effect of, for treat soreness and weakness of waist and knees, lower limb without Power, arthralgia pain due to rheumatism；

Radix Salviae Miltiorrhizae, nature and flavor：Bitter, cold nature have the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, are used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

The rhizome of davallia, nature and flavor：It is bitter, warm-natured, there is the effect of kidney tonifying, promoting blood circulation, hemostasis, for treating kidney deficiency chronic diarrhea and pain in the back, rheumatism The diseases such as numbness pain, dentalgia, tinnitus, the bruise sudden strain of a muscle, bone fracture, appendicitis, alopecia areata, corn；

Teasel root, nature and flavor：Bitter, pungent, tepor has filling liver kidney, strengthening the bones and muscles, continuous injured, stops the effect of uterine bleeding, for treating waist and knee acid Soft, arthralgia pain due to rheumatism, uterine bleeding, threatened abortion, injury from falling down, prepared RADIX DIPSACI with yellow rice wine are chiefly used in arthralgia pain due to rheumatism, injury from falling down, and prepared RADIX DIPSACI with salt solution is chiefly used in waist and knee It is aching and limp；

Yellow Stilbene, nature and flavor：Sweet, tepor has the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Psoralea corylifolia, nature and flavor：Acrid, bitter, warm, have warming kidney and enhancing yang, receive gas, antidiarrheal the effect of, for treat impotence and seminal emission, the enuresis urine Frequently, waist and knee crymodynia, deficiency of the kidney and dyspnea, Diarrhoea, the diseases such as external application curing vitiligo, alopecia areata；

Ramulus Taxilli, nature and flavor：It is bitter, sweet, flat, there is the effect of filling liver kidney, strengthening the bones and muscles, wind-damp dispelling, tocolysis member, for treating rheumatism numbness Bitterly, the diseases such as soreness and weakness of waist and knees, muscles and bones is powerless, uterine bleeding warp is more, blood leaking in gestation, fetal irritability, hypertension；

Rhizoma Chuanxiong, nature and flavor：It is pungent, warm, there is the effect of wet promote breath and open depression, method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, lump in the abdomen abdominal pain, chest side of body thorn Bitterly, tumbling and swelling, arthralgia pain due to rheumatism；

Caulis Spatholobi, nature and flavor：It is bitter, micro-sweet, warm-natured, there is the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation, for treat it is numb in every limb, Quadriplegia, arthralgia pain due to rheumatism, women have through diseases such as uncomfortable, dysmenorrhoea, amenorrhoeas；

Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type abdominal pain, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury；

Radix Aucklandiae, nature and flavor：Acrid, bitter, warm, have promoting qi circulation and relieving pain, effect of reinforcing spleen to promote digestion, for treat chest gastral cavity distending pain, weight after rush down dysentery, Dyspepsia, do not feel like eating, roasted RADIX AUCKLANDIAE reality intestines antidiarrheal, for stomachache of having loose bowels；

Frankincense, nature and flavor：Acrid, bitter, warm has the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation, for treating chest impediment and cardialgia, stomach Gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore；

Myrrh, nature and flavor：It is bitter, flat, there is the effect of removing blood stasis and analgesics, externally used detumescence myogenic, for treating swell and ache for falling dozen extravasated blood, ulcer Swelling and pain, all pains of chest and abdomen, the external curing open sore part such as do not restrain at the diseases long；

Peach kernel, nature and flavor：Bitter sweet is put down, nontoxic, has the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis Store the diseases such as blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood.

Drug of the present invention is the principle based on Chinese traditional treatment degenerative osteoarthropathy, from the disease according to degenerative osteoarthropathy Reason mechanism and pharmacological action are thought：With regard to degenerative osteoarthropathy, each raw material herbal medicine efficacy in drug provided by the present invention is total to It plays, has good therapeutic effect to above-mentioned disease.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned degenerative osteoarthropathy, using the formula The medicine effect of preparation is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention Specific embodiment be described in further detail：

Embodiment 1：

A kind of pill medicine for treating degenerative osteoarthropathy, which is characterized in that each component and the mass parts ratio of the drug It is as follows：

Radix Angelicae Pubescentis 80g, prepared rehmannia root 280g, root of Chinese clematis 95g, Herba Epimedii 120g, root of bidentate achyranthes 230g, rhizoma cibotii 118g, Radix Salviae Miltiorrhizae 120g, the rhizome of davallia 230g, teasel root 120g, yellow Stilbene 260g, psoralea corylifolia 80g, Ramulus Taxilli 120g, Rhizoma Chuanxiong 95g, Caulis Spatholobi 120g, Radix Angelicae Sinensis 120g, Radix Aucklandiae 52g, frankincense 52g, myrrh 200g, peach kernel 120g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of pill medicine for treating degenerative osteoarthropathy, which is characterized in that each component and the mass parts ratio of the drug It is as follows：

Radix Angelicae Pubescentis 90g, prepared rehmannia root 320g, root of Chinese clematis 105g, Herba Epimedii 140g, root of bidentate achyranthes 260g, rhizoma cibotii 130g, Radix Salviae Miltiorrhizae 140g, bone are broken Mend 260g, teasel root 140g, yellow Stilbene 320g, psoralea corylifolia 90g, Ramulus Taxilli 140g, Rhizoma Chuanxiong 105g, Caulis Spatholobi 140g, Radix Angelicae Sinensis 140g, wood Fragrant 60g, frankincense 60g, myrrh 220g, peach kernel 140g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of pill medicine for treating degenerative osteoarthropathy, which is characterized in that each component and the mass parts ratio of the drug It is as follows：

Radix Angelicae Pubescentis 100g, prepared rehmannia root 360g, root of Chinese clematis 120g, Herba Epimedii 160g, root of bidentate achyranthes 300g, rhizoma cibotii 150g, Radix Salviae Miltiorrhizae 160g, bone are broken Mend 300g, teasel root 160g, yellow Stilbene 350g, psoralea corylifolia 100g, Ramulus Taxilli 160g, Rhizoma Chuanxiong 120g, Caulis Spatholobi 160g, Radix Angelicae Sinensis 160g, Radix Aucklandiae 70g, frankincense 70g, myrrh 250g, peach kernel 160g, auxiliary material：Appropriate starch.

Model case：

Through clinical conditions degenerative osteoarthropathy patient totally 1109, the age is 609, only 500 of 61 years old or more It is less than 61 years old.What symptom gradually mitigated in 1109 patients has 811, effective 221, invalid 77.Total effective rate Up to 93%.

Claims (3)

1. a kind of pill medicine for treating degenerative osteoarthropathy, which is characterized in that each component and mass parts of the drug Than as follows：

30~100g of Radix Angelicae Pubescentis, 120~360g of prepared rehmannia root, 60~120g of the root of Chinese clematis, 50~160g of Herba Epimedii, 150~300g of the root of bidentate achyranthes, 60~150g of rhizoma cibotii, 80~160g of Radix Salviae Miltiorrhizae, 150~300g of the rhizome of davallia, 100~160g of teasel root, 100~350g of yellow Stilbene, psoralea corylifolia 60~100g, 100~160g of Ramulus Taxilli, 50~120g of Rhizoma Chuanxiong, 100~160g of Caulis Spatholobi, 80~160g of Radix Angelicae Sinensis, Radix Aucklandiae 15~ 70g, 30~70g of frankincense, 50~250g of myrrh, 80~160g of peach kernel, auxiliary material：Appropriate starch.

2. it is according to claim 1 treatment degenerative osteoarthropathy pill medicine, which is characterized in that the drug it is each A component and mass parts are than as follows：

36~90g of Radix Angelicae Pubescentis, 135~320g of prepared rehmannia root, 70~105g of the root of Chinese clematis, 56~140g of Herba Epimedii, 180~260g of the root of bidentate achyranthes, 70~130g of rhizoma cibotii, 90~140g of Radix Salviae Miltiorrhizae, 180~260g of the rhizome of davallia, 115~140g of teasel root, 115~320g of yellow Stilbene, psoralea corylifolia 70~90g, 115~140g of Ramulus Taxilli, 56~105g of Rhizoma Chuanxiong, 115~140g of Caulis Spatholobi, 90~140g of Radix Angelicae Sinensis, Radix Aucklandiae 18~ 60g, 36~60g of frankincense, 56~220g of myrrh, 90~140g of peach kernel, auxiliary material：Appropriate starch.

3. the pill medicine of the treatment degenerative osteoarthropathy according to claim 1 to 2, which is characterized in that the drug Each component and mass parts than as follows：

Radix Angelicae Pubescentis 80g, prepared rehmannia root 280g, root of Chinese clematis 95g, Herba Epimedii 120g, root of bidentate achyranthes 230g, rhizoma cibotii 118g, Radix Salviae Miltiorrhizae 120g, the rhizome of davallia 230g, teasel root 120g, yellow Stilbene 260g, psoralea corylifolia 80g, Ramulus Taxilli 120g, Rhizoma Chuanxiong 95g, Caulis Spatholobi 120g, Radix Angelicae Sinensis 120g, Radix Aucklandiae 52g, frankincense 52g, myrrh 200g, peach kernel 120g, auxiliary material：Appropriate starch.