CN104027501A - Blood circulation promoting and detoxifying preparation for secondary internal hemorrhoids and preparation method thereof - Google Patents
Blood circulation promoting and detoxifying preparation for secondary internal hemorrhoids and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a blood circulation promoting and detoxifying preparation for secondary internal hemorrhoids. The preparation is prepared from the following main raw materials in parts by weight: 6-15 parts of Chinese angelica, 3-9 parts of coptis, 6-15 parts of poncirus trifoliate, 6-12 parts of pagoda tree pods, 6-15 parts of schizonepeta, 9-25 parts of red bean, 30-50 parts of carbonized sanguisorba root, 3-6 parts of raw rhubarb, 6-12 parts of meat simmering nutmeg, 5-9 parts of bunge cherry seeds, 6-12 parts of alisma (stir-fried), 8-15 parts of almond and 18-30 parts of purslane. The preparation based on the principle of treating internal hemorrhoids Chinese medicine is scientific in formula and convenient in use and carrying, has the effects of promoting blood circulation and detoxifying, and can be used for effectively treating the secondary internal hemorrhoids. Moreover, the preparation disclosed by the invention also has the excellent effects that the selected materials are all traditional Chinese medicinal materials, so that the preparation does not have any toxic or side effects; medicament sources are readily available, and the cost of the medicinal materials is low, so that the burden of patients can be lightened.
Description
Technical field
The invention discloses a kind of preparation, particularly a kind of the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation and method for making.The invention belongs to Chinese medicine field.
background technology
Hemorrhoid are a kind of commonly encountered diseases that are positioned at anus position.Hemorrhoid can be divided into internal hemorrhoid, external hemorrhoid and mixed hemorrhoid.Blood stasis is positioned at be called " internal hemorrhoid " of anus the inside mucosa, is called " external hemorrhoid " near being positioned at anal orifice inner side, and what the two had is called " mixed hemorrhoid ".More than internal hemorrhoid is born in tooth trace and anus 3cm place.In " surgery great achievement hemorrhoid ", say: " internal hemorrhoid, anus in, is defecated hemorrhage as arrow, separates to finish with hands and presses, and side enters for a good while." point out that internal hemorrhoid, taking hemorrhage and deviate from as cardinal symptom, mostly is painless soft lump.Internal hemorrhoid is the highest commonly encountered diseases of sickness rate in all hemorrhoid.
Internal hemorrhoid is one more common in hemorrhoid, also larger to the harm of human body.According to the difference of the pathological change of internal hemorrhoid and development degree, often internal hemorrhoid is divided into clinically to three phases.First phase internal hemorrhoid symptom is lighter, and under sight glass, visible mucosa is the nodositas differing in size, and matter is soft, and color is red; While referring to inspection, the softness of pressing, mucous membrane surface is very thin, is easily frayed and hemorrhage when stool, and stool is normal to be with blood or to bleed, because of blood stasis small volume, therefore do not deviate from outside anus.Second phase, internal hemorrhoid was attached most importance to compared with first phase, and blood stasis is larger, hemorrhoid mucosal tissue weakness, while exerting oneself defecation, blood stasis emerges in outside anus, can get back to voluntarily after an action of the bowels anal, when stool, excrement piece friction hemorrhoid mucomembranous surface, causes and has blood in stool, and does not have blood in stool and can be toilet paper band blood, bleeds, penetrates blood not etc.StageⅢhemorrhoid is the late stage of internal hemorrhoid.Owing to suffering from the internal hemorrhoid time longer, blood stasis increases, after an action of the bowels blood stasis emerge in anus outer, even cough, exert oneself, walk and also can emerge in outside anus when work, must send anal back to hands, or just can send anal back to after rest.
Second phase, internal hemorrhoid was serious compared with first phase internal hemorrhoid, and blood stasis is larger, protuberance, and when defecation, Zhi core is deviate from outside anus, and Hui Na voluntarily after an action of the bowels hemorrhagely after an action of the bowels reduces than the initial stage.The second phase clinical symptoms performance of internal hemorrhoid mainly contains: 1. have blood in stool: in defecation or hemorrhage after an action of the bowels, color is scarlet, and stool surface is with a small amount of blood sometimes, or toilet paper is incarnadined, sometimes for bleeding or penetrating blood.Due to feces galling mucosa, or too exert oneself during because of defecation, intravascular pressure increases, so that cirso-angiorrhexis, has spurting hemorrhage just time.2. deviate from: because blood stasis volume increases, being subject to the extruding of feces when defecation, making it separate and deviate from outside anus with flesh layer gradually, is that 1--2 blood stasis is deviate from simultaneously sometimes, is whole blood stasis sometimes and deviates from simultaneously with mucous membrane of rectum.Only in the time of defecation, deviate from first, after an action of the bowels can self-resetting.Symptom, compared with severe one, needs after deviating to return with hand push, or lies up, and can reset.Serious symptom person, deviating from during except defecation, all firmly, walking, cough, sneeze, squat down etc., all may deviate from.3. pain: simple internal hemorrhoid, generally without pain, sometimes only feel podex falling inflation or difficult defecation.As inflammation struttuer, in hemorrhoid, there are thrombosis or incarceration, there is pain; As deviate from not reset person in time, pain increases the weight of; As there is incarceration, and there is the necrosis of festering, cause anus edge inflammation edema, sharp ache, patient's uneasy in either sitting or lying.4. mucus flows out: mucous membrane of rectum is subject to the stimulation of blood stasis for a long time, causes secretions increase; Late period, internal hemorrhoid, because of Sphincter ani chalasia, often had secretions to be flowed out by anus.When the lighter defecates, flow out, severe one does not also flow out when defecation naturally, pollutes underwear, and patient is extremely inconvenient.In the time that internal hemorrhoid is deviate from, secretions is more.5. pruritus: because of secretions or the stimulation of deviating from blood stasis, make anus moist unclean around, eczema and pruritus occur, scratch where it itches sometimes because internal hemorrhoid is deviate from and caused because of reflection.In addition, internal hemorrhoid also can cause some complication: 1, have blood in stool, bleed and serious spray blood all will cause iron deficiency anemia.2,, because secretions increase overflows outside anus, not only pollution clothes, also easily causes pain eczema, for female patient, also will cause the outbreak of some gynaecopathias etc.3, constipation, constipation due to dry stool, be easy to squeeze and hinder blood stasis so that have blood in stool, very painful when patient Chang Yin defecation, so bear by force inconvenience, makes stool drier, so repeatedly, forms vicious cycle.4, have blood in stool, this vicious cycle of pain and constipation, make people's anorexia, cause the not normal and malnutrition of the not normal and whole human body balance of spleen and stomach function, easily cause the generations such as hepatorenal disease, chronic colitis, anal fistula, intestinal cancer.Therefore, internal hemorrhoid causes great threat to people healthy, after checking out and suffering from hemorrhoid, and actively partner treatment.
Application publication number is CN 103520510A(application number 201310513279.9) Chinese patent literature a kind of by name " a kind of Chinese medicine composition for the treatment of internal hemorrhoid and preparation method thereof " disclosed, this Chinese medicine composition is made up of Radix Rehmanniae 12 ~ 17g, Radix Paeoniae Rubra 7 ~ 10g, Radix Angelicae Sinensis 6 ~ 9g, Poria 8 ~ 13g, Radix Scutellariae 6 ~ 9g, Flos Sophorae 8 ~ 10g, Radix Sanguisorbae 7 ~ 11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6 ~ 9g, the Rhizoma Atractylodis Macrocephalae 6 ~ 10g, Radix Glycyrrhizae 4 ~ 7g, Radix Saposhnikoviae 7 ~ 10g, Cortex Moutan 8 ~ 11g.Application publication number is CN 103655962A(application number 201310683312.2) Chinese patent literature a kind of by name " a kind of Chinese drugs agentia for the treatment of internal hemorrhoid " disclosed, it is by 8～15 parts of Flos Sauropi changiani leaf, 6～12 parts of Fructus Mumes, 12～18 parts of Galla Chinensiss, 8～14 parts of Radix Sophorae Flavescentiss, 10～15 parts of Rhizoma Belamcandae, 12～18 parts of stir-baked SQUAMA MANITISs, 8～12 parts of Fructus Cannabiss, 7～11 parts of Cortex Moutans, 10～20 parts of compositions of Flos Chrysanthemi.
In a word, Chinese medicine is being obtained certain effect aspect treatment internal hemorrhoid, but also has some problems: the medicine effect for the treatment of at present internal hemorrhoid is not good enough, can not fundamentally treat internal hemorrhoid, can not effect a radical cure, and the medicine having also can have side effects.
Summary of the invention
In order to make up the deficiencies in the prior art, one of object of the present invention is to provide one to prepare simple, easy to use, portable the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation of the present invention can, for the reason of internal hemorrhoid, fundamentally be cured internal hemorrhoid, has effect of promoting blood circulation and detoxication.
Another object of the present invention is to provide the preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation.
Technical scheme of the present invention is:
Second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 6-15 part, Rhizoma Coptidis 3-9 part, JUKE 6-15 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Semen Phaseoli 9-25 part, charred Radix Sanguisorbae 30-50 part, Radix Et Rhizoma Rhei 3-6 part, Semen Myristicae 6-12 part, Semen Pruni 5-9 part, Rhizoma Alismatis (stir-fry) 6-12 part, Semen Armeniacae Amarum 8-15 part, Herba Portulacae 18-30 part.
Second phase internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 8-12 part, Rhizoma Coptidis 5-7 part, JUKE 9-11 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Semen Phaseoli 15-19 part, charred Radix Sanguisorbae 35-45 part, Radix Et Rhizoma Rhei 4-5 part, Semen Myristicae 7-11 part, Semen Pruni 6-8 part, Rhizoma Alismatis (stir-fry) 8-10 part, Semen Armeniacae Amarum 10-12 part, Herba Portulacae 22-26 part.
Second phase internal hemorrhoid promoting blood circulation and detoxication preparation, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from: 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Coptidis, 10 parts of JUKE, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 17 parts of Semen Phaseolis, 40 parts of charred Radix Sanguisorbae, 4.5 parts of Radix Et Rhizoma Rhei, 9 parts of Semen Myristicae, 7 parts of Semen Prunis, 9 parts of Rhizoma Alismatis (stir-fry), 11 parts, Semen Armeniacae Amarum, 24 parts of Herba Portulacaes.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 8-16 hour, boil 15-45 minute with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 20-60 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 80-120 mesh sieve;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 0.6-1.4 hour after mixing, water consumption be crude drug gross weight 3-5 doubly, filter, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (2) is placed in Oleum Sesami and soaks 10-14 hour (preferably 12 hours).
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (2) boils 20-40 minute (preferably 30 minutes) with marmite with slow fire.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (2) medicine oil temperature is down to 30-50 DEG C (preferably 40 DEG C).
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (3) is crossed 90-110 mesh sieve (preferably 100 mesh sieves).
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (4) decocts with water 0.8-1.2 hour (preferably 1 hour).
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preferred scheme is that step (4) water consumption is doubly (preferably 4 times) of 3.5-4.5 of crude drug gross weight.
Best using method: for making the present invention reach best therapeutic effect, make unguentum, every day 2 times, be applied in right amount affected part, 5 days courses for the treatment of in sooner or later getting.
The pharmacological effect of each crude drug is respectively:
Radix Angelicae Sinensis: base is former: be the dry root of umbelliferae angelica.Nature and flavor: sweet, acrid, warm.Gui Jing: return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Cure mainly: for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Rhizoma Coptidis: base is former: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.Nature and flavor: hardship, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly: tie mutually damp and hot middle resistance, feeling of fullness vomiting for cold and heat.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
JUKE: have another name called that Tielizhai, passeris montani saturati are not squatted, Fructus Aurantii, JUKE is the dry mature fruit of rutaceae Citrus aurantium Linn., fragrant circle and trifoliate orange etc.Nature and flavor: cold nature, bitter in the mouth, acid, be the traditional authentic medicinal herbs of China.Effect: the function with dispelling the stagnated QI removing food stagnancy.Cure mainly: cure mainly the diseases such as food stagnation, the breast abdomen stagnation of QI, distending pain dysentery, constipation, uterine prolapse, gastroptosis, proctoptosis.
The Fructus Sophorae: base is former: this product is the dry mature fruit of leguminous plant Chinese scholartree.Nature and flavor: hardship, cold.Gui Jing: return liver, large intestine channel.Effect: clearing away heat-fire, cooling blood for hemostasis.Cure mainly: have blood in stool for intestinal heat, hemorrhoid are swollen hemorrhage, liver-heat headache, dizzy conjunctival congestion.
Herba Schizonepetae: base is former: this product is the dry aerial parts of labiate Herba Schizonepetae.Nature and flavor: acrid in the mouth, tepor.Gui Jing: return lung, Liver Channel.Effect: the loose wind that induces sweat, rash.Cure mainly: for flu, headache, measles, rubella, skin infection from the beginning of.
Semen Phaseoli: base is former: be the dry mature seed of leguminous plant Semen Phaseoli or Semen Phaseoli.Nature and flavor: sweet, sour, flat.Gui Jing: GUIXIN, small intestine meridian.Effect: inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.Cure mainly: for edema distension, beriberi limb is swollen, jaundice dark coloured urine, rheumatism pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
Charred Radix Sanguisorbae: be the root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.Nature and flavor: bitter in the mouth, acid; Cold; Nontoxic.Gui Jing: return liver, lung, kidney, large intestine channel.Effect: cooling blood for hemostasis, heat-clearing and toxic substances removing.Cure mainly: control haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
Radix Et Rhizoma Rhei: nature and flavor: bitter in the mouth; Cold in nature.Gui Jing: return stomach, large intestine, liver, spleen channel.Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: stagnant for Gastrointestinal excess heat, constipation.
Semen Myristicae: another name: character used in proper names and in rendering some foreign names is arrested and strangled, Fructus Amomi Rotundus, flesh fruit, top meat, semen myristicae, bundle ground, fiber crops are lost.Nature and flavor: acrid in the mouth, temperature.Gui Jing: return spleen, stomach, large intestine channel.Effect: warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents.Cure mainly: for Deficiency and coldness of spleen and stomach, incessant chronic diarrhea, abdominal distention, lack of appetite vomiting.
Semen Pruni: base is former: be the dry mature seed of rosaceous plant Prunus humilis, strongly fragrant Lee or Prunus pedunculata Maxim..Nature and flavor: pungent, bitter, sweet, flat.Gui Jing: return spleen, large intestine, small intestine meridian.Effect: moisturize laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Cure mainly: for intestine-dryness due to consumption of fluid. stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
Rhizoma Alismatis: base is former: be the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis.Nature and flavor: sweet in the mouth, cold.Gui Jing: return kidney, urinary bladder channel.Effect: diuresis, clearing away damp-heat.Cure mainly: for dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Semen Armeniacae Amarum: bitter in the mouth, tepor.Effect: relieving cough and asthma, loosening bowel to relieve constipation.Cure mainly: for cough due to consumptive disease, asthma, breast abdomen is against vexed; Dryness of the intestine constipation, constipation with dry stool.
Herba Portulacae: base is former: be the dry aerial parts of portulacaceous plant Herba Portulacae.Nature and flavor: acid, cold.Gui Jing: return liver, large intestine channel.Effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: for toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis.
The principle of preparation of the present invention based on traditional Chinese medical herbal treatment internal hemorrhoid, prescription science, easy to use, be easy to carry, there is effect of promoting blood circulation and detoxication, can effectively treat the second stage of internal hemorrhoid.In addition, excellent results of the present invention also shows: selected materials is Chinese medicine material, without any side effects; Medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from (getting 5g for every part): 6 parts of Radix Angelicae Sinensis, 3 parts of Rhizoma Coptidis, 6 parts of JUKE, 6 parts of the Fructuss Sophorae, 6 parts of Herba Schizonepetae, 9 parts of Semen Phaseolis, 30 parts of charred Radix Sanguisorbae, 3 parts of Radix Et Rhizoma Rhei, 6 parts of Semen Myristicae, 5 parts of Semen Prunis, 6 parts of Rhizoma Alismatis (stir-fry), 8 parts, Semen Armeniacae Amarum, 18 parts of Herba Portulacaes.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 8 hours, boil 15 minutes with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 20 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 80 mesh sieves;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 0.6 hour after mixing, water consumption is 3 times of crude drug gross weight, filters, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
model case one:grandson XX, man, 23 years old, university students.Patient's readme has suffered from hemorrhoid for a long time, but also not serious, just occasional has bloodstain in finding just, As time goes on, hemorrhoid are serious before recently, hurt like hell when defecation, has the symptom of bleeding and produce, but also sensation hemorrhoid is deviate from outside anus, so remove examination in hospital, be diagnosed as the second stage of internal hemorrhoid, take some medicines that hospital opens, effect is undesirable.Use this to implement 1 gained second phase internal hemorrhoid promoting blood circulation and detoxication preparation, adopt every day 2 times, be applied in right amount affected part, 5 days courses for the treatment of in sooner or later getting.Use 2 days, patient's pain relief, malaise symptoms is alleviated; Use 3 days, patient's main story of having blood in stool disappears, and Zhi core is deviate from the outer symptom of anus and also disappeared; Continue to use 2 days, patient's symptom that feels uneasy disappears completely.
embodiment 2second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from (getting 10g for every part): 15 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Coptidis, 15 parts of JUKE, 12 parts of the Fructuss Sophorae, 15 parts of Herba Schizonepetae, 25 parts of Semen Phaseolis, 50 parts of charred Radix Sanguisorbae, 6 parts of Radix Et Rhizoma Rhei, 12 parts of Semen Myristicae, 9 parts of Semen Prunis, 12 parts of Rhizoma Alismatis (stir-fry), 15 parts, Semen Armeniacae Amarum, 30 parts of Herba Portulacaes.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 16 hours, boil 45 minutes with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 60 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 120 mesh sieves;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 1.4 hours after mixing, water consumption is 5 times of crude drug gross weight, filters, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
embodiment 3second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from (getting 15g for every part): 8 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Coptidis, 9 parts of JUKE, 8 parts of the Fructuss Sophorae, 9 parts of Herba Schizonepetae, 15 parts of Semen Phaseolis, 35 parts of charred Radix Sanguisorbae, 4 parts of Radix Et Rhizoma Rhei, 7 parts of Semen Myristicae, 6 parts of Semen Prunis, 8 parts of Rhizoma Alismatis (stir-fry), 10 parts, Semen Armeniacae Amarum, 22 parts of Herba Portulacaes.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 10 hours, boil 20 minutes with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 30 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 90 mesh sieves;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 0.8 hour after mixing, water consumption is 3.5 times of crude drug gross weight, filters, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
model case two: Dong XX, man, 36 years old, teacher.Abnormal defecation difficulty is closely felt in patient's readme, and often feels that anus place has mucus to flow out, and has pain when defecation, just middle band blood, and color is scarlet, and sometimes has the symptom of bleeding, and is diagnosed as on inspection the second stage of internal hemorrhoid.Use 3 gained second phase of the present embodiment internal hemorrhoid promoting blood circulation and detoxication preparation, adopt every day 2 times, be applied in right amount affected part, 5 days courses for the treatment of in sooner or later getting.Use 1 day, patient's symptom that feels uneasy all alleviates to some extent; Use 3 days, patient's transference cure of having blood in stool, bleed, when defecation, pain alleviates; Continue to use 3 days the recovery from illness of patient's self-induction.
embodiment 4second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from (getting 20g for every part): 12 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Coptidis, 11 parts of JUKE, 10 parts of the Fructuss Sophorae, 11 parts of Herba Schizonepetae, 19 parts of Semen Phaseolis, 45 parts of charred Radix Sanguisorbae, 5 parts of Radix Et Rhizoma Rhei, 11 parts of Semen Myristicae, 8 parts of Semen Prunis, 10 parts of Rhizoma Alismatis (stir-fry), 12 parts, Semen Armeniacae Amarum, 26 parts of Herba Portulacaes.
The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 14 hours, boil 40 minutes with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 50 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 110 mesh sieves;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 1.2 hours after mixing, water consumption is 4.5 times of crude drug gross weight, filters, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
model case three: Zhao XX, man, 43 years old.When patient's readme unknown cause defecation, relatively require great effort, even with bloodstain in just, due to originally thinking and getting angry, but after a period of time, disease increases the weight of, and anus place pruritus is hard to bear, just in bloodstain increase before, and special pain, takes medicine treatment, invalid.Use 4 gained second phase of the present embodiment internal hemorrhoid promoting blood circulation and detoxication preparation, adopt every day 2 times, be applied in right amount affected part, 5 days courses for the treatment of in sooner or later getting.Use 2 days, patient's pruritus alleviates, pain relief; Use 4 days, patient's symptom of having blood in stool alleviates, and pruritus disappears; Continue to use 2 days, patient's malaise symptoms disappears completely, self-induction recovery from illness.
embodiment 5second phase internal hemorrhoid promoting blood circulation and detoxication preparation, takes off the primary raw material of stating weight proportion and is prepared from (getting 30g for every part): 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Coptidis, 10 parts of JUKE, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 17 parts of Semen Phaseolis, 40 parts of charred Radix Sanguisorbae, 4.5 parts of Radix Et Rhizoma Rhei, 9 parts of Semen Myristicae, 7 parts of Semen Prunis, 9 parts of Rhizoma Alismatis (stir-fry), 11 parts, Semen Armeniacae Amarum, 24 parts of Herba Portulacaes.The preparation method of above-mentioned the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, preparation process is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 12 hours, boil 30 minutes with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 40 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 100 mesh sieves;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 1 hour after mixing, water consumption is 4 times of crude drug gross weight, filters, it is 1.36-1.38(50 DEG C that filtrate is concentrated into relative density) clear paste;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
experimental example 1the clinical practice of embodiment 5 gained second phase internal hemorrhoid promoting blood circulation and detoxication preparation: in February, 2007-2009 year August, screen 200 routine patients in 6 hospitals, wherein women's 107 examples, male's 93 examples.Test 3 days before, carries out Continuous Observation to this crowd, records symptom and variation, be divided at random two groups, experimental group and matched group, experimental group is taken embodiment 5 products obtained therefroms, and matched group is taken other medicine (conventional medicine such as MAYINGLONGZHICHUANGGAO, ZHICHUAN SHUAN, YUNNAN BAIYAO ZHICHUANG GAO).Using method is: every day 2 times, be applied in right amount affected part, 5 days courses for the treatment of in sooner or later getting.Curative effect situation criterion: cure: use a course for the treatment of of this product, patient without mucus flow out, have blood in stool, the symptom such as pain, malaise symptoms disappears completely; Effective: use a course for the treatment of of this product, pruritus, pain symptom alleviate, malaise symptoms alleviates or part disappears; Invalid: use a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
The compliance test result of table 1: embodiment 5 gained second phase internal hemorrhoid promoting blood circulation and detoxication preparation
Therapeutic effect: cure 72 examples (72%), effective 23 examples (23%), invalid 5 examples (5%), total effective rate 95%.Successful is better than matched group.
Between the operating period, self-induction symptom and other symptom variation are as shown in table 2.
Table 2:
Oleum Sesami has effect of loosening bowel to relieve constipation, removing toxic substances, granulation promoting, can effectively treat dryness of the intestine constipation, ulcer, skin ulcer swollen etc.The present invention selects Oleum Sesami soak medicine, make medicine can better its effect of performance, there is the effect of promoting blood circulation and detoxication, remarkable to the second stage of internal hemorrhoid treatment effect.Use 1 day, more than 52% patient's symptom is improved, pain relief, and Zhi core is deviate from transference cure; Use 3 days, more than 72% patient's malaise symptoms improves, the transference cure of having blood in stool, and pain alleviates; Use 5 days, more than 95% patient's malaise symptoms improves, the recovery from illness of some patients were self-induction.Experimental group uses 5 days, and effective percentage can reach 95%, and matched group is only 72%.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 6-15 part, Rhizoma Coptidis 3-9 part, JUKE 6-15 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Semen Phaseoli 9-25 part, charred Radix Sanguisorbae 30-50 part, Radix Et Rhizoma Rhei 3-6 part, Semen Myristicae 6-12 part, Semen Pruni 5-9 part, Rhizoma Alismatis (stir-fry) 6-12 part, Semen Armeniacae Amarum 8-15 part, Herba Portulacae 18-30 part.
2. the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 8-12 part, Rhizoma Coptidis 5-7 part, JUKE 9-11 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Semen Phaseoli 15-19 part, charred Radix Sanguisorbae 35-45 part, Radix Et Rhizoma Rhei 4-5 part, Semen Myristicae 7-11 part, Semen Pruni 6-8 part, Rhizoma Alismatis (stir-fry) 8-10 part, Semen Armeniacae Amarum 10-12 part, Herba Portulacae 22-26 part.
3. the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Coptidis, 10 parts of JUKE, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 17 parts of Semen Phaseolis, 40 parts of charred Radix Sanguisorbae, 4.5 parts of Radix Et Rhizoma Rhei, 9 parts of Semen Myristicae, 7 parts of Semen Prunis, 9 parts of Rhizoma Alismatis (stir-fry), 11 parts, Semen Armeniacae Amarum, 24 parts of Herba Portulacaes.
4. according to the preparation method of the arbitrary described the second stage of internal hemorrhoid promoting blood circulation and detoxication preparation of claim 1-3, it is characterized in that, step is as follows:
(1) Semen Armeniacae Amarum is mashed, be ground into Semen Armeniacae Amarum mud;
(2) Radix Angelicae Sinensis, the Fructus Sophorae, Radix Et Rhizoma Rhei and Rhizoma Alismatis (stir-fry) are placed in to Oleum Sesami and soak 8-16 hour, boil 15-45 minute with slow fire with marmite, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure that to wait afterwards medicine oil temperature to be down to 20-60 DEG C of elimination medicinal residues for subsequent use;
(3) JUKE, charred Radix Sanguisorbae and Semen Myristicae mixed powder are broken into fine powder, cross 80-120 mesh sieve;
(4) will Rhizoma Coptidis, Herba Schizonepetae, Semen Phaseoli, Semen Pruni and Herba Portulacae decoct with water 0.6-1.4 hour after mixing, water consumption be crude drug gross weight 3-5 doubly, filter, filtrate is concentrated into the clear paste that relative density is 1.36-1.38;
(5) step (2)-(4) gains are mixed, add step (1) gained Semen Armeniacae Amarum mud, stir, be concentrated in right amount, obtain preparation unguentum.
5. preparation method according to claim 4, is characterized in that: step (2) is placed in Oleum Sesami and soaks 10-14 hour (preferably 12 hours).
6. preparation method according to claim 4, is characterized in that: step (2) boils 20-40 minute (preferably 30 minutes) with marmite with slow fire.
7. preparation method according to claim 4, is characterized in that: step (2) medicine oil temperature is down to 30-50 DEG C (preferably 40 DEG C).
8. preparation method according to claim 4, is characterized in that: step (3) is crossed 90-110 mesh sieve (preferably 100 mesh sieves).
9. preparation method according to claim 4, is characterized in that: step (4) decocts with water 0.8-1.2 hour (preferably 1 hour).
10. preparation method according to claim 4, is characterized in that: step (4) water consumption is doubly (preferably 4 times) of 3.5-4.5 of crude drug gross weight.
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