CN104012971A - 改善记忆力的保健食品 - Google Patents
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- A—HUMAN NECESSITIES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
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Abstract
本发明涉及一种改善记忆力的保健食品，是一种以中药为原料药制备的改善记忆力的保健食品。本发明包括下列质量比例的原料：益智仁60-90份、西洋参90-120份、灵芝孢子粉30-60份、银杏叶40-80份、远志40-80份、丹参25-40份。本发明可以以常规的中药制剂方法制备成任何一种常用口服剂型，如颗粒剂、片剂、胶囊剂、口服液等。本发明的保健食品具有辅助改善记忆力的功能。
Description
技术领域
本发明属于生物医药领域，具体涉及一种改善记忆力的保健食品。
背景技术
记忆是脑的一种功能或一种属性，并且是一个多阶段的动态神经过程。一般认为，记忆是指获得的信息或经验在脑内储存和提取的神经活动过程。自古以来，记忆一直是人们十分关注的课题，当前仍是神经生物学研究的热点。记忆力对于生活是非常重要的，如果一个人总是遗忘事情，对他的生活与工作会带来很大的影响。
记忆力减退属于中医“健忘”、“喜忘”、“多忘”、“好忘”等病范畴，是脑功能减退的重要症状。中医认为“心藏神、肝藏魂、肺藏魄、脾藏意、肾藏志”，人的思维活动和五脏均有非常密切的关系。此外，“脑为元神之府”，脑髓盈满，则耳目聪明，精力充沛；脑髓空虚，可出现记忆减退。其病性有虚实之分，虚者多是心虚、肾虚、脾虚、气血衰少和脑髓不足；实者多为瘀血、痰浊、肝气郁滞、心经浊火。
目前市场上的辅助改善记忆的保健食品主要含有如下功效成分：
(1)脂类
脂类可以促进脑细胞发育和神经髓鞘的形成，并保证其维持良好的功能。不饱和脂肪酸、磷脂、胆固醇等脂类是构成细胞膜的基本成分，DHA等是健脑的重要物质，磷脂代谢后分解出胆碱，后者是合成乙酰胆碱的重要原料。
(2)蛋白质和氨基酸类
脑细胞的代谢需要靠蛋白质来维持大脑的各种运动状态。参与神经传导、负责信息传递的化学物质——神经递质也是由蛋白质的分解产物氨基酸或其衍生物所构成的。氨基酸的平衡是维持大脑正常活动与功能的重要条件。
(3)矿物质和微量元素
钙、镁、钠、钾等协同维持神经的应激性。缺钙可影响信息的神经传导，使神经、肌肉的兴奋性失调，人就会变得敏感，情绪不稳定，注意力难以集中，脑力工作不易持久。磷是脑力活动中的重要元素之一，参与生物氧化、调节能量和物质代谢。磷是构成卵磷脂、脑磷 脂等的重要成分，对维护大脑和神经细胞的结构与功能起着十分重要的作用。铁可使红细胞运氧的能力加强，脑组织供氧充足。人体缺锌会影响智力，妨碍正常的学习记忆功能。
(4)维生素
维生素是维护身体健康，提高智力活动的重要营养素之一。如维生素C能保护生物膜，是保护脑功能的重要物质。B族维生素尤其是维生素B1参与碳水化物代谢，产生能量，保证神经系统的正常功能。维生素E能维持脑细胞活力，并能预防脑细胞衰退及脑力疲劳。
(5)中草药
中药中的茯苓、酸枣仁、龙眼、枸杞、红景天、五味子等均有补脑功效。银杏叶可以改善脑部血液循环，具有加速人的反应能力、提高记忆力和集中精力的功效，人参皂苷可以增强对血氧的利用率，促进学习记忆。
发明内容
随着人民生活水平的提高，探讨中医药对亚健康的调治思路，寻找有助于亚健康者的方药越来越重要。
综合本领域现有技术以及存在的问题，本发明的目的在于提供一种改善记忆力的保健食品。
为达到上述目的，本发明包括下列质量比例的原料：益智仁60-90份、西洋参90-120份、灵芝孢子粉30-60份、银杏叶40-80份、远志40-80份、丹参25-40份。
本发明的保健食品，在上述原料的基础的上，加入适当的食用或药用辅料，可以以常规的中药制剂方法制备成任何一种常用口服剂型，如颗粒剂、片剂、胶囊剂、口服液等。本发明的保健食品具有辅助改善记忆力的功能。
具体实施方式
实施例1.
取益智仁70g、西洋参100g、灵芝孢子粉45g、银杏叶60g、远志60g、丹参30g，粉碎后用8倍乙醇回流提取，过滤，残渣再用10倍水提取，合并两次提取液，浓缩，喷雾干燥，加入糊精等制成颗粒剂。
下面采用实验进一步介绍本发明改善记忆力的作用。
实验方法：取健康雄性小白鼠，分为给药组、空白组和模型对照组，空白对照组和模型对照组灌服等溶剂的蒸馏水，给药7天，末次给药后30min，除正常对照组腹腔注射生理盐水外，其余各组均腹腔注射东莨菪碱5mg/kg，10min后进行跳台法训练。24小时后测试，记录5min内小鼠的跳下潜伏期和错误次数。
实验结果：与正常对照组相比，模型对照组小鼠记忆明显衰退，表现为错误次数增加，潜伏期缩短。与模型组比较，给药组的能使小鼠错误次数明显减少，潜伏期明显延长。表明本发明可以改善东莨菪碱所致小鼠记忆障碍，本发明具有辅助改善记忆的功能。
表.本发明对东莨菪碱所致记忆获得障碍动物记忆改善作用
与模型对照组比较*P﹤0.05，与空白对照组比较#P﹤0.05 。
Claims (1)
1.改善记忆力的保健食品，其特征在于，包括下列质量比例的原料：益智仁60-90份、西洋参90-120份、灵芝孢子粉30-60份、银杏叶40-80份、远志40-80份、丹参25-40份。
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