CN104010628A - 一种包裹ly294002的药物制剂 - Google Patents

一种包裹ly294002的药物制剂 Download PDF

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Publication number
CN104010628A
CN104010628A CN201280064823.XA CN201280064823A CN104010628A CN 104010628 A CN104010628 A CN 104010628A CN 201280064823 A CN201280064823 A CN 201280064823A CN 104010628 A CN104010628 A CN 104010628A
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CN
China
Prior art keywords
pharmaceutical preparation
parcel
acid
phosphatide
preparation
Prior art date
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Pending
Application number
CN201280064823.XA
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English (en)
Inventor
张文芳
戴杰
陆翔
谢日清
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Suzhou Nanocrystal Pharma Co ltd
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Suzhou Nanocrystal Pharma Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Suzhou Nanocrystal Pharma Co ltd filed Critical Suzhou Nanocrystal Pharma Co ltd
Priority to CN201280064823.XA priority Critical patent/CN104010628A/zh
Publication of CN104010628A publication Critical patent/CN104010628A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明公开了一种包裹LY294002的药物制剂，LY294002包裹在药物辅料中，药物与辅料的重量比为：1∶1-1∶20，有效控制了LY294002的释放，可以制成临床上治疗PI3K活性相关障碍疾病的药物，尤其是可以用来治疗淋巴系统肿瘤以及治疗淋巴系统肿瘤转移。

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CN201280064823.XA 2011-12-30 2012-04-13 一种包裹ly294002的药物制剂 Pending CN104010628A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201280064823.XA CN104010628A (zh) 2011-12-30 2012-04-13 一种包裹ly294002的药物制剂

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201110453641 2011-12-30
CN201110453641.9 2011-12-30
CN201280064823.XA CN104010628A (zh) 2011-12-30 2012-04-13 一种包裹ly294002的药物制剂
PCT/CN2012/000500 WO2013097266A1 (zh) 2011-12-30 2012-04-13 一种包裹ly294002的药物制剂

Publications (1)

Publication Number Publication Date
CN104010628A true CN104010628A (zh) 2014-08-27

Family

ID=48696307

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280064823.XA Pending CN104010628A (zh) 2011-12-30 2012-04-13 一种包裹ly294002的药物制剂

Country Status (2)

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CN (1) CN104010628A (zh)
WO (1) WO2013097266A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514317A (zh) * 2020-04-09 2020-08-11 温州医科大学附属第一医院 一种淋巴系统双模态成像造影剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1846679A (zh) * 2006-01-23 2006-10-18 济南帅华医药科技有限公司 含氨甲喋呤及其增效剂的缓释注射剂
WO2007120897A2 (en) * 2006-04-13 2007-10-25 The Trustees Of Columbia University In The City Of New York Compositions and intraluminal devices for inhibiting vascular stenosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005051229A2 (en) * 2003-11-24 2005-06-09 Avantec Vascular Corporation Devices delivering therapeutic agents and methods regarding the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1846679A (zh) * 2006-01-23 2006-10-18 济南帅华医药科技有限公司 含氨甲喋呤及其增效剂的缓释注射剂
WO2007120897A2 (en) * 2006-04-13 2007-10-25 The Trustees Of Columbia University In The City Of New York Compositions and intraluminal devices for inhibiting vascular stenosis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HARFOUCHE R.,ET AL.: "nanoparticle-mediated targeting of phosphatidylinositol-3-kinase signaling inhibits angiogenesis", 《ANGIOGENESIS》 *
杨雪峰 等: "纳米乳给药系统的应用", 《广东农业科学》 *
谢霞 等: "LY294002对SGC7901/VCR细胞VCR耐药逆转作用的研究", 《重庆医学》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514317A (zh) * 2020-04-09 2020-08-11 温州医科大学附属第一医院 一种淋巴系统双模态成像造影剂
CN111514317B (zh) * 2020-04-09 2022-08-19 温州医科大学附属第一医院 一种淋巴系统双模态成像造影剂

Also Published As

Publication number Publication date
WO2013097266A1 (zh) 2013-07-04

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Application publication date: 20140827