CN104010628A - 一种包裹ly294002的药物制剂 - Google Patents
一种包裹ly294002的药物制剂 Download PDFInfo
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- CN104010628A CN104010628A CN201280064823.XA CN201280064823A CN104010628A CN 104010628 A CN104010628 A CN 104010628A CN 201280064823 A CN201280064823 A CN 201280064823A CN 104010628 A CN104010628 A CN 104010628A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
本发明公开了一种包裹LY294002的药物制剂,LY294002包裹在药物辅料中,药物与辅料的重量比为:1∶1-1∶20,有效控制了LY294002的释放,可以制成临床上治疗PI3K活性相关障碍疾病的药物,尤其是可以用来治疗淋巴系统肿瘤以及治疗淋巴系统肿瘤转移。
Description
PCT国内申请,说明书已公开。
Claims (1)
- PCT国内申请,权利要求书已公开。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201280064823.XA CN104010628A (zh) | 2011-12-30 | 2012-04-13 | 一种包裹ly294002的药物制剂 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110453641.9 | 2011-12-30 | ||
CN201110453641 | 2011-12-30 | ||
PCT/CN2012/000500 WO2013097266A1 (zh) | 2011-12-30 | 2012-04-13 | 一种包裹ly294002的药物制剂 |
CN201280064823.XA CN104010628A (zh) | 2011-12-30 | 2012-04-13 | 一种包裹ly294002的药物制剂 |
Publications (1)
Publication Number | Publication Date |
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CN104010628A true CN104010628A (zh) | 2014-08-27 |
Family
ID=48696307
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201280064823.XA Pending CN104010628A (zh) | 2011-12-30 | 2012-04-13 | 一种包裹ly294002的药物制剂 |
Country Status (2)
Country | Link |
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CN (1) | CN104010628A (zh) |
WO (1) | WO2013097266A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111514317A (zh) * | 2020-04-09 | 2020-08-11 | 温州医科大学附属第一医院 | 一种淋巴系统双模态成像造影剂 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1846679A (zh) * | 2006-01-23 | 2006-10-18 | 济南帅华医药科技有限公司 | 含氨甲喋呤及其增效剂的缓释注射剂 |
WO2007120897A2 (en) * | 2006-04-13 | 2007-10-25 | The Trustees Of Columbia University In The City Of New York | Compositions and intraluminal devices for inhibiting vascular stenosis |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005051229A2 (en) * | 2003-11-24 | 2005-06-09 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
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2012
- 2012-04-13 WO PCT/CN2012/000500 patent/WO2013097266A1/zh active Application Filing
- 2012-04-13 CN CN201280064823.XA patent/CN104010628A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1846679A (zh) * | 2006-01-23 | 2006-10-18 | 济南帅华医药科技有限公司 | 含氨甲喋呤及其增效剂的缓释注射剂 |
WO2007120897A2 (en) * | 2006-04-13 | 2007-10-25 | The Trustees Of Columbia University In The City Of New York | Compositions and intraluminal devices for inhibiting vascular stenosis |
Non-Patent Citations (3)
Title |
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HARFOUCHE R.,ET AL.: "nanoparticle-mediated targeting of phosphatidylinositol-3-kinase signaling inhibits angiogenesis", 《ANGIOGENESIS》 * |
杨雪峰 等: "纳米乳给药系统的应用", 《广东农业科学》 * |
谢霞 等: "LY294002对SGC7901/VCR细胞VCR耐药逆转作用的研究", 《重庆医学》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111514317A (zh) * | 2020-04-09 | 2020-08-11 | 温州医科大学附属第一医院 | 一种淋巴系统双模态成像造影剂 |
CN111514317B (zh) * | 2020-04-09 | 2022-08-19 | 温州医科大学附属第一医院 | 一种淋巴系统双模态成像造影剂 |
Also Published As
Publication number | Publication date |
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WO2013097266A1 (zh) | 2013-07-04 |
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Application publication date: 20140827 |