CN103990057A - Drug for treating rheumatoid bone diseases and preparation method thereof - Google Patents

Abstract

The invention discloses a drug for treating rheumatoid bone diseases. The drug is prepared by steps of mixing the following raw materials in parts by weight: 15-20 parts of angelica sinensis, 8-10 parts of panax notoginseng, 12-15 parts of pawpaw, 12-15 parts of cortex acanthopanacis, 12-15vrhizoma drynariae, 20-30 parts of achyranthes bidentata, 12-15 parts of flos carthami, 10-15 parts of ligusticum wallichii, 25-30 parts of salviae miltiorrhizae, 15-20 parts of radix clematidis, 6-10 parts of amomum, 20-25 parts of coix seeds, 10-15 parts of honey-fried licorice root and 1-4 parts of fried centipede; and finally crushing and grinding into powder. The drug disclosed by the invention can take effect quickly, has the advantages of good effect, high recovery rate and no side effects. The invention also discloses preparation of the drug for treating rheumatoid bone diseases.

Description

A kind of medicine for the treatment of rheumatic osteopathia and preparation method thereof

Technical field

The present invention relates to field of traditional Chinese, specifically refer to a kind of medicine for the treatment of rheumatic osteopathia and preparation method thereof.

Background technology

Its pathogenesis of rheumatic osteopathia is mainly that QI and blood numbness resistance is obstructed, and lose due to moisten and support in muscle arteries and veins joint.Cause the bad disease causing of nutrition supply that comprises flesh, ligament, synovial bursa, fascia.Arthropathy, is outbreak and alleviates the chronic course of disease alternately outward still with swelling and moving obstacle apart from pain, is a kind of commonly encountered diseases, frequently-occurring disease, and damage yang-energy, invades internal organs, very large to human health damage; The Chinese and western drugs for the treatment of rheumatic osteopathia is more at present, but exists curative effect slower, needs certain hour, and the side effect that western medicine hormones, analgesic bring, has increased the weight of the human body extent of damage, or therapeutic effect is not good, and is difficult to the defect of radical cure.

Summary of the invention

The object of the invention is to provide in order to overcome the deficiency of prior art a kind of rapid-action, effective, cure rate is high, the medicine of the treatment rheumatic osteopathia that has no side effect.

The present invention also provides a kind of preparation method of this medicine simultaneously.

The technical scheme providing is for achieving the above object:

Treat a medicine for rheumatic osteopathia, by following raw materials according, mix by weight rear pulverizing pulverize and form:

Radix Angelicae Sinensis 15-20, Radix Notoginseng 8-10, Fructus Chaenomelis 12-15, Cortex Acanthopancis 12-15, Rhizoma Drynariae 12-15, Radix Achyranthis Bidentatae 20-30, Flos Carthami 12-15, Rhizoma Chuanxiong 10-15, Radix Salviae Miltiorrhizae 25-30, Radix Clematidis 15-20, Fructus Amomi 6-10, Semen Coicis 20-25, Radix Glycyrrhizae Preparata 10-15, Scolopendra (processed) 1-4.

Preferred: Radix Angelicae Sinensis 15, Radix Notoginseng 8, Fructus Chaenomelis 12, Cortex Acanthopancis 12, Rhizoma Drynariae 12, Radix Achyranthis Bidentatae 20, Flos Carthami 12, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 25, Radix Clematidis 15, Fructus Amomi 6, Semen Coicis 20, Radix Glycyrrhizae Preparata 10, Scolopendra (processed) 4.

A preparation method for the treatment of the medicine of rheumatic osteopathia, consists of the following step:

A, powder process: get by weight Radix Angelicae Sinensis, Radix Notoginseng, Fructus Chaenomelis, Cortex Acanthopancis, Rhizoma Drynariae, Radix Achyranthis Bidentatae, Flos Carthami, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Clematidis, Fructus Amomi, Semen Coicis, Radix Glycyrrhizae Preparata, Scolopendra (processed), pulverizing after mixing, porphyrize powder, stand-by;

B, preparation: above-mentioned fine powder is stirred, incapsulate.

Rheumatic osteopathia is to take limbs joint pain, miserable, numb, emphatically and the moving obstacle disease that is cardinal symptom because of what the damp and hot heresy that is affected by the cold caused.There is clinically feature gradual or that repeatedly show effect.Human necks, shoulders waist lower limb and other joints, limbs pain, numbness, swelling and other malaise symptoms; It comprises: scapulohumeral periarthritis, osteomyelitis, cervical spondylosis, gonarthritis, hyperosteogeny, femur head necrosis, sjogren syndrome, prolapse of lumbar intervertebral disc, rheumatoid arthritis.

Its pathogenic factor: antibacterial, virus, heredity, gonadal hormone etc. are main cause.Normal take the risk factor that cold, humidity, fatigue, malnutrition, wound, Nervous and Mental Factors etc. are primary disease.Wherein, part is to cause that due to external force damage and microorganism invasion bacterial inflammation causes, and is more caused by aseptic inflammation." aseptic inflammation " is that the position of human body generation body disorder disease and obstinate pain does not have antibacterial to infect, and there is no the inflammation of source of disease bacterium, thereby antibiotic therapy is invalid.Aseptic inflammation is common in the diseases such as hyperosteogeny, prolapse of lumbar intervertebral disc, cervical spondylosis, scapulohumeral periarthritis, spinal canal stenosis, psoas muscle pain, numbness.

Main clinic symptoms-the pain of rheumatic osteopathia, numbness, swelling etc., its root is just that aseptic inflammation is to the stimulation of diseased region soft tissue and damage, the chemical irritation that aseptic inflammation causes acts in canalis spinalis or the outer teleneuron of canalis spinalis, stimulate body to produce antibody, there is immunopathogenesis damage and cause a disease, causing pain; Doctor trained in Western medicine adds hormone with antibiotic has certain therapeutical effect to " bacterial inflammation ", and hormonal dependent and the side effect bringing are difficult to avoid, and cure the symptoms, not the disease; To the aseptic inflammation antibiotic of rheumatic osteopathia but without any effect.Chinese and western medicine never has good medicine and way to the treatment of aseptic inflammation at present, Here it is at present Chinese and western medicine to rheumatic osteopathia-particularly hyperosteogeny, rheumatism, rheumatoid, intervertebral disk hernia, gout, femur head necrosis, ankylosing spondylitis, synovitis etc. often unsatisfactory curative effect, the basic reason that is difficult to radical cure.

The traditional Chinese medical science has a well-known saying---and " control wind and first control blood, blood wind is from going out ".Meridians dredging, blood circulation promoting and blood stasis dispelling, improves whole body and local microcirculation, is the key point of eliminating aseptic inflammation.Medicine of the present invention, take theory of Chinese medical science as basis, from the comprehensive adjustment of the enterprising pedestrian's body of disease root.To reconcile better the immunologic function of whole human body from pathogenic factors, adjust the reaction of whole human body.In changing before, the drawback of western medical treatment rheumatism; Make it bring into play better curative effect.For the cause of disease, the maximum feature of medicine of the present invention: its formula is unique, novel, drug dose preparation is unique, reasonable; Drug dose reasonably combined, has strengthened the synergism between medicine, has increased technology content, in treatment rheumatic osteopathia field, occupies technical advantage; Safely, efficient, thorough treatment is sharpest edges.Oral medicine of the present invention, accordingly disease and select medicine.Reach strengthening the body resistance, expelling wind and removing dampness, cold expelling relieve the pain, meridians dredging, the effect of blood circulation promoting and blood stasis dispelling; Radix Angelicae Sinensis in medicine, Radix Glycyrrhizae, Fructus Chaenomelis, Fructus Amomi, Semen Coicis have that invigorating middle warmer is gentle, spleen reinforcing is nourished blood, QI invigorating removing dampness, the but effect of phlegm and relieving cough; Add again Flos Carthami, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, pseudo-ginseng blood-circulation-invigovating dredging collateral, stasis-dispelling and pain-killing, blood-activating and qi-promoting, subduing swelling and relieving pain; The effect of additional Radix Clematidis, Cortex Acanthopancis, Rhizoma Drynariae expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, the kidney invigorating bone strengthening, the pain relieving of curing the wound; The effect that adds again Radix Achyranthis Bidentatae, Scolopendra anti-inflammatory and antalgic, the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, makes the efficacy of a drug focus of going directly, and plays treating both the principal and secondary aspects of a disease, gets instant result, disease alleviates rapidly.This Drug therapy feature is: acts on rapid, rapid-action, patient and easily accepts, and evident in efficacy, cure rate high.And stable curative effect, is difficult for recurrence, has no side effect, and raw material easily obtains.Can reach strengthening the body resistance completely, get rid of evils dehumidifying, effect of dissolving stasis and relieving pain.

In a word, medicine of the present invention, is the comprehensive adjustment from the enterprising pedestrian's body of morbidity root of rheumatic osteopathia.To reconcile better the immunologic function of whole human body from pathogenic factors, adjust the reaction of whole human body.Should expelling wind and cold dampness, blood circulation promoting and blood stasis dispelling again, dredge the meridian passage, pain relieving, antiinflammatory, subsides a swelling, fills blood, and reaches the effect for the treatment of both the principal and secondary aspects of a disease; Treatment is because wind-cold damp pathogen invasion causes energy and blood of human body obstructed, various rheumatic osteopathia due to meridians are obstructed, comprise that scapulohumeral periarthritis, osteomyelitis, cervical spondylosis, gonarthritis, hyperosteogeny, femur head necrosis, sjogren syndrome, prolapse of lumbar intervertebral disc, the various symptoms of rheumatoid arthritis all have unique therapeutic effect; The diseases such as fracture, muscle and tendon injury are also had to good therapeutic effect, and cure rate is high.

Treatment rheumatic osteopathia drug use method of the present invention: medicine is packed into " 1 " number capsule, each oral 2 sooner or later.

Below by clinical observation on the therapeutic effect, test and further set forth beneficial effect of the present invention.

This clinical trial 200 examples, meet the rheumatic osteopathia patient of tcm diagnosis standard, all derive from patient medical history, wherein routine women's 140 examples of male 60; Age 25-40 year 40 examples, age 41-84 year 160 examples;

Therapeutic Method: each 2 1.0 grams of oral medicines of the present invention, every day 2 times, first quarter moon is a course for the treatment of, altogether 2-3 the course for the treatment of.

Curative effect determinate standard: the symptom change degree of take is curative effect determinate standard.

Observed result: this clinical observation 172 examples, clinical cure 49 examples (28.49%), effective 84 examples (48.83%), 33 examples (19.18%) that take a turn for the better, total effective rate 96.5%.All case histories all have no adverse reaction.To clinical cure personnel random inspection 20 people, follow up a case by regular visits to and within 2 years, have no recurrence.

Refer to 4 row model cases:

Case history 1: so-and-so Nan54Sui people from Dunhua City of king, this patient suffered from rheumatism in 2011 and has no improvement through many hospitalizes, in March, 2012,24Lai Wo institute seeks medical advice, and haves a medical check-up: chronic facies, and coolness of extremities, fear of cold, numbness, waist lower limb ache pain are according to sign inspection and lab testing RF396IU/ml, ESR93mm/h, ASO200 unit, WBC5.0 * 109/L, is diagnosed as rheumatoid acute active stage, oral medicine the 3rd day, symptom is alleviated gradually.Transference cure after one course for the treatment of, continues oral this medicine to second course for the treatment of, to consolidate curative effect, now returns to one's perfect health, and emotion is optimistic.

Case 2: Zhang, female 65 years old, in Dunhua City, occupation: workman.In on February 5th, 2010 because of whole body arthralgia companion moving obstacle to our hospital; Main suit is because of the flu of catching a cold of doing manual work of going out the year before; Have a medical check-up: extremities joint symmetrical swelling, limitation of activity, is interrupted and takes containing hormone drug half a year, occurs Ku Xinshi face.Withdrawing rear pain increases the weight of, finger-joint distortion, the atrophy of limb muscle severe, both hands near-end articulations digitorum manus, two wrist, two knee joint, two ankle and toe joint severe swelling companion limitation of activity, difficulty is bent and stretched in duplex joint, chemical examination: rheumatoid factor 1362IU/ml, erythrocyte sedimentation rate 77mm/h, anti-" O " 400U, routine blood test: leukocyte 9.9 * 109/L, erythrocyte 4.36 * 1012/L, hemoglobin 121g/L.Diagnosis: rheumatoid disease, symptom improvement after oral medicine of the present invention a week, sour swollen symptom alleviates, and serve on 2 courses for the treatment of of this medicine, clinical cure, activity freely, can normally do manual work.

So-and-so sub-village of city's South Platform, Nv33Sui Dunhua City of case 3 kings, because praising weight, pull, go the film making of city hospital, outstanding through x ray examination 4-5 lumbar vertebra, on January 27th, 2013 out of admiration for a famous person Lai Wo institute seek medical advice, have a medical check-up: lumbago and skelalgia is serious, involve sciatica, stand up, cough aggravation while sucking, lumbar vertebra limitation of activity, diagnosis: prolapse of lumbar intervertebral disc.The reset of simultaneously massaging of oral medicine, remission on the same day, movable voluntarily, oral drugs one week, clinical cure.

Within 50 years old, before 4 years, without inducement, there is both hands articulations digitorum manus symmetrical swelling companion pain in so-and-so female of case 4 pipes; then extremities joint pain; both hands are clenched fist limited; double knee joint severe swelling companion difficulty in walking; medical certain hospital diagnosis " rheumatoid arthritis "; not good through therapeutic effect, medical my x of institute ray examination shows that edge, joint has bony spur formation, joint space to narrow down, diagnosis: osteoarthritis; 2 courses for the treatment of of oral this invention medicine, joint transference cure, laboratory indexes is normal.Follow up a case by regular visits to so far, joint is asymptomatic, clinical cure.

The specific embodiment

Embodiment 1

Treat a medicine for rheumatic osteopathia, by following traditional Chinese medicine raw by weight unit " gram " form:

Radix Angelicae Sinensis 15 Radix Notoginseng 8 Fructus Chaenomelis 12 Cortex Acanthopancis 12 Rhizoma Drynariae 12 Radix Achyranthis Bidentatae 20 Flos Carthami 12 Rhizoma Chuanxiong 10 Radix Salviae Miltiorrhizae 25 Radix Clematidis 15 Fructus Amomi 6 Semen Coicis 20 Radix Glycyrrhizae Preparata 10 Scolopendra (processed) 4;

Preparation method:

A, powder process: by Radix Angelicae Sinensis, Radix Notoginseng, Fructus Chaenomelis, Cortex Acanthopancis, Rhizoma Drynariae, Radix Achyranthis Bidentatae, Flos Carthami, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Clematidis, Fructus Amomi, Semen Coicis, Radix Glycyrrhizae Preparata, Scolopendra (processed), pulverizing after mixing, porphyrize powder, stand-by;

B, preparation: above-mentioned fine powder is stirred, pack " 1 " capsule into.

Embodiment 2

Radix Angelicae Sinensis 20 Radix Notoginseng 10 Fructus Chaenomelis 15 Cortex Acanthopancis 15 Rhizoma Drynariae 15 Radix Achyranthis Bidentatae 30 Flos Carthami 15 Rhizoma Chuanxiong 15 Radix Salviae Miltiorrhizae 30 Radix Clematidis 20 Fructus Amomi 10 Semen Coicis 25 Radix Glycyrrhizae Preparata 15 Scolopendra (processed) 4;

The same EXAMPLE l of its preparation method.

Embodiment 3

Radix Angelicae Sinensis 20 Radix Notoginseng 8 Fructus Chaenomelis 15 Cortex Acanthopancis 15 Rhizoma Drynariae 12 Radix Achyranthis Bidentatae 20 Flos Carthami 15 Rhizoma Chuanxiong 15 Radix Salviae Miltiorrhizae 30 Radix Clematidis 20 Fructus Amomi 10 Semen Coicis 20 Radix Glycyrrhizae Preparata 10 Scolopendra (processed) 1;

The same EXAMPLE l of its preparation method.

The detailed description of the above-mentioned illustrated example of the present invention, but the invention is not restricted to above-mentioned institute implementation method, in scope in right described in interpellation book technical scheme, by some modifications, can implement different implementation methods, and this modification should belong to scope of the present invention.

Claims (3)

1. treat a medicine for rheumatic osteopathia, by following raw materials according, mix by weight rear pulverizing pulverize and form:

Radix Angelicae Sinensis 15-20, Radix Notoginseng 8-10, Fructus Chaenomelis 12-15, Cortex Acanthopancis 12-15, Rhizoma Drynariae 12-15, Radix Achyranthis Bidentatae 20-30, Flos Carthami 12-15, Rhizoma Chuanxiong 10-15, Radix Salviae Miltiorrhizae 25-30, Radix Clematidis 15-20, Fructus Amomi 6-10, Semen Coicis 20-25, Radix Glycyrrhizae Preparata 10-15, Scolopendra (processed) 1-4.

2. a kind of medicine for the treatment of rheumatic osteopathia according to claim 1, mixes by weight rear pulverizing pulverize by following raw materials according and forms:

Radix Angelicae Sinensis 15, Radix Notoginseng 8, Fructus Chaenomelis 12, Cortex Acanthopancis 12, Rhizoma Drynariae 12, Radix Achyranthis Bidentatae 20, Flos Carthami 12, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 25, Radix Clematidis 15, Fructus Amomi 6, Semen Coicis 20, Radix Glycyrrhizae Preparata 10, Scolopendra (processed) 4.

3. a kind of preparation method for the treatment of the medicine of rheumatic osteopathia according to claim 1, consists of the following step:

A, powder process: get by weight Radix Angelicae Sinensis, Radix Notoginseng, Fructus Chaenomelis, Cortex Acanthopancis, Rhizoma Drynariae, Radix Achyranthis Bidentatae, Flos Carthami, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Clematidis, Fructus Amomi, Semen Coicis, Radix Glycyrrhizae Preparata, Scolopendra (processed), pulverizing after mixing, porphyrize powder, stand-by;

B, preparation: above-mentioned fine powder is stirred, incapsulate .