CN103989682B - 使用centhaquin的治疗法 - Google Patents
使用centhaquin的治疗法 Download PDFInfo
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- CN103989682B CN103989682B CN201410085543.8A CN201410085543A CN103989682B CN 103989682 B CN103989682 B CN 103989682B CN 201410085543 A CN201410085543 A CN 201410085543A CN 103989682 B CN103989682 B CN 103989682B
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- centhaquin
- clonidine
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
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- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
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| US17425709P | 2009-04-30 | 2009-04-30 | |
| US61/174257 | 2009-04-30 | ||
| CN201080029672.5A CN102458399B (zh) | 2009-04-30 | 2010-04-29 | centhaquin的新制药用途 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201080029672.5A Division CN102458399B (zh) | 2009-04-30 | 2010-04-29 | centhaquin的新制药用途 |
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| CN103989682A CN103989682A (zh) | 2014-08-20 |
| CN103989682B true CN103989682B (zh) | 2016-03-30 |
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| CN201410085543.8A Active CN103989682B (zh) | 2009-04-30 | 2010-04-29 | 使用centhaquin的治疗法 |
| CN201080029672.5A Active CN102458399B (zh) | 2009-04-30 | 2010-04-29 | centhaquin的新制药用途 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201080029672.5A Active CN102458399B (zh) | 2009-04-30 | 2010-04-29 | centhaquin的新制药用途 |
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| ES (1) | ES2614813T3 (https=) |
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| AU2010241564B2 (en) | 2009-04-30 | 2014-07-31 | Midwestern University | Novel therapeutic treatments using centhaquin |
| CN110354267A (zh) * | 2012-08-31 | 2019-10-22 | 法尔麦兹公司 | 用于低血压复苏的方法和组合物 |
| WO2016061583A1 (en) * | 2014-10-17 | 2016-04-21 | University Of Virginia Patent Foundation | Compositions and methods for treating pituitary tumors |
| BR112020022395A2 (pt) * | 2018-05-03 | 2021-04-13 | Midwestern University | Alterações em receptores de endotelina em seguida a hemorragia e ressuscitação por centaquina |
| WO2022240964A1 (en) * | 2021-05-11 | 2022-11-17 | Pharmazz, Inc. | Pharmaceutical composition and method for treatment of acute respiratory distress syndrome (ards) in corona virus disease (covid-19) |
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| DE2421382A1 (de) | 1974-05-03 | 1975-11-20 | Council Scient Ind Res | 1-substituierte 4-(beta-2-chinolylaethyl)- piperazine und deren 1,2,3,4-tetrahydrochinolinanaloge |
| JPS604186B2 (ja) | 1974-05-13 | 1985-02-01 | カウンシル、オブ、サイエンテイフイツク、アンド、インダストリアルリサーチ | １―ｍ―トリル―４―（Ｂ―２―キノリエチル）―ピペラジンの製造法 |
| US3983121A (en) | 1974-07-01 | 1976-09-28 | Council Of Scientific And Industrial Research | 1-Substituted 4-(β-2-quinolylethyl)piperazines and 1,2,3,4-tetrahydroquinolyl-ethyl analogues thereof |
| DE2557784C2 (de) * | 1975-12-22 | 1986-04-17 | Hoechst Ag, 6230 Frankfurt | Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate |
| US4761417A (en) * | 1982-05-14 | 1988-08-02 | Maroko Peter R | Compounds, compositions and method of treatments for improving circulatory performance |
| CA1217141A (en) | 1983-04-26 | 1987-01-27 | Frank J. Macri | Norepinephrine potentiated compositions and method of use |
| US5055470A (en) | 1989-06-01 | 1991-10-08 | Bristol-Myers Squibb Co. | Method of treatment of ischemia in brain |
| US5922681A (en) | 1992-09-14 | 1999-07-13 | Warner-Lambert Company | Endothelin antagonists |
| US20040063719A1 (en) * | 1998-08-26 | 2004-04-01 | Queen's University At Kingston | Combination therapy using antihypertensive agents and endothelin antagonists |
| US6545048B1 (en) | 1999-06-29 | 2003-04-08 | California Institute Of Technology | Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity |
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| SE0004455D0 (sv) | 2000-12-01 | 2000-12-01 | Milos Pekny | Method for neuron regeneration in the central nervous system |
| WO2002049630A2 (en) | 2000-12-21 | 2002-06-27 | Bristol-Myers Squibb Company | Method for preventing or treating pain by administering an endothelin antagonist |
| US20030232787A1 (en) | 2001-05-08 | 2003-12-18 | Dooley David James | Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic |
| WO2003009805A2 (en) | 2001-07-23 | 2003-02-06 | Brigham And Women's Hospital, Inc. | Analgesic methods using endothelin receptor ligands |
| US7030082B2 (en) | 2001-09-07 | 2006-04-18 | Nobex Corporation | Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith |
| US7973064B2 (en) * | 2001-11-27 | 2011-07-05 | The Board Of Trustees Of The University Of Illinois | Method and composition for potentiating an opiate analgesic |
| US7351692B2 (en) * | 2002-06-19 | 2008-04-01 | The Board Of Trustees Of The University Of Illinois | Method and composition for potentiating the antipyretic action of a nonopioid analgesic |
| CA2502848C (en) | 2002-10-24 | 2012-10-02 | The Board Of Trustees Of The University Of Illinois | Use of irl-1620 and paclitaxel for preventing and treating breast tumors |
| GB0226931D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
| DK1583541T3 (da) | 2002-11-20 | 2011-04-11 | Neuronova Ab | Forbindelser og fremgangsmåder til at øge neurogenese |
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| JP2009506119A (ja) | 2005-08-31 | 2009-02-12 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 選択的アンドロゲン受容体モジュレーターを用いる腎疾患、熱傷、創傷および脊髄損傷の処置 |
| US9829494B2 (en) | 2005-12-01 | 2017-11-28 | Adrenomed Ag | Methods of treatment using ADM antibodies |
| AU2007230887A1 (en) | 2006-03-23 | 2007-10-04 | Amylin Pharmaceuticals, Inc. | Endothelin and endothelin receptor agonists in the treatment of metabolic diseases |
| PL2182977T4 (pl) | 2007-08-21 | 2017-01-31 | Midwestern University | Kompozycje do leczenia udaru lub incydentów mózgowo-naczyniowych za pomocą agonisty receptora endoteliny B |
| US20100189802A1 (en) | 2007-08-21 | 2010-07-29 | Scott And White Memorial Hospital And Scott, Sherwood, And Brindley Foundation | Method for treatment of vascular hyperpermeability |
| CN101374259B (zh) | 2007-08-22 | 2012-08-08 | 华为技术有限公司 | 实现多媒体彩铃和多媒体彩像业务的方法和装置 |
| EP2165706A1 (en) | 2008-09-18 | 2010-03-24 | BioAlliance Pharma | Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers. |
| BRPI1013904A2 (pt) | 2009-04-30 | 2016-07-19 | Univ Midwestern | método e composição para tratar cetoacidose diabética |
| AU2010241564B2 (en) | 2009-04-30 | 2014-07-31 | Midwestern University | Novel therapeutic treatments using centhaquin |
| US8518969B2 (en) | 2010-06-17 | 2013-08-27 | Janssen Pharmaceutica Nv | Cyclohexyl-azetidinyl antagonists of CCR2 |
| KR101418941B1 (ko) | 2011-04-04 | 2014-07-15 | 서울대학교병원 | 엔도텔린을 유효성분으로 함유하는 허혈성질환 치료용 조성물 |
| CN110354267A (zh) | 2012-08-31 | 2019-10-22 | 法尔麦兹公司 | 用于低血压复苏的方法和组合物 |
| WO2015006324A2 (en) | 2013-07-08 | 2015-01-15 | Midwesterern University | Compositions and methods for treating neuropsychiatric disorders using an endothelin-b receptor agonist |
| BR112020022395A2 (pt) | 2018-05-03 | 2021-04-13 | Midwestern University | Alterações em receptores de endotelina em seguida a hemorragia e ressuscitação por centaquina |
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| JP5727642B2 (ja) | 2015-06-03 |
| BRPI1013903B1 (pt) | 2020-03-03 |
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| US20180085461A1 (en) | 2018-03-29 |
| CA2759791C (en) | 2018-04-10 |
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| CN103989682A (zh) | 2014-08-20 |
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| AU2010241564A1 (en) | 2011-11-17 |
| EP2424529A2 (en) | 2012-03-07 |
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| PL2424529T3 (pl) | 2017-06-30 |
| ES2614813T3 (es) | 2017-06-02 |
| EP2424529A4 (en) | 2012-11-28 |
| AU2010241564B2 (en) | 2014-07-31 |
| JP2012525422A (ja) | 2012-10-22 |
| WO2010127096A3 (en) | 2011-03-24 |
| BRPI1013903A2 (pt) | 2016-07-19 |
| EP2424529B1 (en) | 2016-12-28 |
| US20120083447A1 (en) | 2012-04-05 |
| US10828368B2 (en) | 2020-11-10 |
| CA2759791A1 (en) | 2010-11-04 |
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