CN103977109B - Drug for treating paralytic ileus and promoting stomach and intestine function recovery after abdominal operation and preparation method thereof - Google Patents
Drug for treating paralytic ileus and promoting stomach and intestine function recovery after abdominal operation and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a drug for treating paralytic ileus and promoting stomach and intestine function recovery after an abdominal operation and a preparation method thereof. The drug is prepared from 20 parts by weight of radix astragali, 10 parts by weight of magnolia cortex, 10 parts by weight of bitter orange, 20 parts by weight of raw licorice root, 15 parts by weight of peach seed, 20 parts by weight of ligusticum wallichii, 25 parts by weight of honeysuckle flower and 25 parts by weight of dandelion. The drug is a claybank decoction and has a light traditional Chinese medicine fragrance. The preparation method comprises the following steps of a, weighing the above raw materials according to a formula, b, decocting the above eight medicines by water three times, for 2h each time, wherein in the first decoction process, the amount of used water is four times that of the medicines, and in the second and third decoction processes, the amount of used water is three times that of the medicines, merging the decoctions and carrying out filtration, and c, removing decoction residues, carrying out reduced-pressure condensation on the decoction, carrying out stirring, carrying out dissolution, cooling the solution, carrying out centrifugation, carrying out encapsulation, carrying out steam disinfection, carrying out packaging and carrying out warehousing. The drug can adjust a human stress state after an operation, can improve and keep stability of the inner environment, can promote stomach and intestine function recovery after an abdominal operation, is conducive to human body recovery after the operation and is safe and convenient in use.
Description
Technical field:
The present invention relates to a kind of treat paralytic ileus, promote abdominal post-operation restoration of gastrointestinal function medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Owing to damage, mechanical stimulus and the anesthesia of abdominal operation is to neural retardance, makes gastrointestinal function be suppressed by certain, cause early postoperation that enteroparalysis occurs.Gastrointestinal function recovery is slow to be caused organismic internal environment disorderly and induces various complication.Stomach in Patients intestinal function early recovery, takes food as early as possible, for improving body nutrition, increase Abwehrkraft des Koepers, promoting that wound healing, minimizing post-operative complication are highly beneficial.
Doctor trained in Western medicine there is no preferable Therapeutic Method to abdominal post-operation restoration of gastrointestinal function now, and only generally requires 3-5 days by clear-cutting forestland, therefore seeks effective tcm therapy and promotes that abdominal post-operation restoration of gastrointestinal function has positive clinical meaning.
TCM Therapy mainly has the methods such as oral Chinese medicine method, rectal perfusion dose regimen, applying Chinese medicine to the umbilicus, massage, acupoint treatment in recent years, all has certain effect.But consult reference materials according to me, there is not yet Same Chinese Herbal Medicine of the present invention the most both at home and abroad and application report at abdominal postoperative is administered orally.
Summary of the invention
It is an object of the invention to provide a kind of stress state that can adjust postoperative body, improve and keep a kind of of stablizing of interior environment, the beneficially rehabilitation of Post operation body to treat paralytic ileus, the medicine of promotion abdominal post-operation restoration of gastrointestinal function.Another object of the present invention is just to provide the preparation method of this medicine.
The technical scheme is that and be achieved in that: a kind for the treatment of paralytic ileus, promote the medicine of abdominal post-operation restoration of gastrointestinal function, it is made up of the crude drug of following weight proportioning: Radix Astragali 15-30 part Cortex Magnoliae Officinalis 5-15 part Fructus Aurantii 5-15 part Radix Glycyrrhizae 15-30 part Semen Persicae 10-30 part Rhizoma Chuanxiong 10-30 part Flos Lonicerae 20-30 part Herba Taraxaci 20-30 part.
A kind of treat paralytic ileus, promote abdominal post-operation restoration of gastrointestinal function medicine, the most each crude drug ratio range is: Radix Astragali 18-25 part Cortex Magnoliae Officinalis 6-12 part Fructus Aurantii 6-8 part Radix Glycyrrhizae 18-25 part Semen Persicae 13-25 part Rhizoma Chuanxiong 13-25 part Flos Lonicerae 23-28 part Herba Taraxaci 23-28 part.
A kind of treat paralytic ileus, promote abdominal post-operation restoration of gastrointestinal function medicine, the most each crude drug weight proportion is: 15 parts of Rhizoma Chuanxiongs of 20 parts of Semen Persicaes of 10 parts of Radix Glycyrrhizae of 10 parts of Fructus Aurantiis of 20 parts of Cortex Magnoliae Officinalis of the Radix Astragali, 25 parts of Herba Taraxacis of 20 portions of Flos Loniceraes 25 parts.
A kind of treat paralytic ileus, promote abdominal post-operation restoration of gastrointestinal function medicine, it is characterised in that described medicine is brown color decoction, slightly Chinese medicine fragrance.
The preparation method of a kind of medicine treating paralytic ileus, promotion abdominal post-operation restoration of gastrointestinal function, a. weighs each crude drug by recipe ratio；B. by above 8 herbal medicine soak by water three times, wherein: for the first time with 4 times amount water, second time and third time 3 times amount water, every time decoction 2 hours, collecting decoction, filtration；C. discard medicinal residues, by medicinal liquid concentrating under reduced pressure, stir, dissolve, cool down, be centrifuged, embedding, steam sterilization packaging warehouse-in.
It is an advantage of the current invention that: the stress state of postoperative body 1, can be adjusted, improve and keep stablizing of interior environment, promoting abdominal post-operation restoration of gastrointestinal function, the beneficially rehabilitation of Post operation body.2, applying reasonable, convenient, safety, meet surgical postoperative principle of medication, clinic is promoted the use of.
Patient's using effect witnesses
In July, 2012 in December ,-2012 we abdominal surgery gastrointestinal function recovery situation is observed, the Chinese drug-treated group using the Western medicine group of western medicine routine treatment, conventional therapy to add medicine decoction of the present invention is compared, result is in following table.
2 groups of postoperative borborygmus recover, aerofluxus and defecation time compare
Note: compare with Western medicine group, * P ＜ 0.01
Wherein witness 1: promote abdominal post-operation restoration of gastrointestinal function
Tan XX, female, 52 years old, people from Shaodong County, Hunan Province, identification card number: 43052419590916XXXX, telephone number: 1327220XXXX, rectal cancer patient, Post operation is administered orally the decoction that medicine of the present invention is made, passage of gas by anus two days later, anus defecation after four days, abdominal wound healing is good.
Witness 2: treatment paralytic ileus
Zhu XX, female, 62 years old, people from Longhui, Hunan Province,, there is abdominal distention, stomachache in identification card number: 43052219520312XXXX, telephone number: 1350842XXXX, and anus stops defecation aerofluxus, the decoction that oral medicine of the present invention is made, passage of gas by anus after a day, anus defecation after three days.
Witness 3: promote abdominal post-operation restoration of gastrointestinal function
X recklessly, female, 70 years old, Hunan Province Shaoyang City people, identification card number: 43052319430203XXXX, telephone number: 1521197XXXX, colorectal cancer patients, Post operation, the decoction that oral medicine of the present invention is made, passage of gas by anus after three days, anus defecation after four days, abdominal wound healing is good.
Witness 4: treatment paralytic ileus
Soviet Union XX, man, 63 years old, people from Shaoyang County, Hunan Province, identification card number: 43262119490912XXXX, telephone number: 1318729XXXX, intestinal obstruction patient, abdominal distention, stomachache occur, anus stops defecation aerofluxus, the decoction that oral medicine of the present invention is made, passage of gas by anus after a day, anus defecation after three days.
Witness 5: promote abdominal post-operation restoration of gastrointestinal function
Zhao X, female, 64 years old, people from Shaoyang County, Hunan Province, identification card number: 43262119490212XXXX, telephone number: 1357498XXXX, gastrointestinal stromal tumor patient, Post operation, the decoction that oral medicine of the present invention is made, passage of gas by anus after three days, anus defecation after four days.
Witness 6: promote abdominal post-operation restoration of gastrointestinal function
Wu XX, man, 32 years old, people from Shuyang County, Jiangsu Province, identification card number: 32082319810519XXXX, telephone number: 1351517XXXX, rupture of spleen patient, Post operation, the decoction that oral medicine of the present invention is made, passage of gas by anus after two days, anus defecation after three days.
Witness 7: promote abdominal post-operation restoration of gastrointestinal function
5 X, female, 49 years old, people from Xinshao County of Hunan Province, identification card number: 43052319640101XXXX, telephone number: 1357491XXXX, acute appendicitis localized peritonitis patient, Post operation, the decoction that oral medicine of the present invention is made, passage of gas by anus after three days, anus defecation after four days.
Accompanying drawing explanation
Fig. 1: present invention process general flow chart.
Detailed description of the invention
Weigh by following weight proportion and only expect:
A kind of treat paralytic ileus, promote abdominal post-operation restoration of gastrointestinal function medicine, the most each crude drug weight proportion is: 15 parts of Rhizoma Chuanxiongs of 20 parts of Semen Persicaes of 10 parts of Radix Glycyrrhizae of 10 parts of Fructus Aurantiis of 20 parts of Cortex Magnoliae Officinalis of the Radix Astragali, 25 parts of Herba Taraxacis of 20 portions of Flos Loniceraes 25 parts.The above-mentioned prepared slices of Chinese crude drugs all require standard according to Pharmacopoeia of the People's Republic of China version first in 2010.Medicine described in the present invention is brown color decoction, slightly Chinese medicine fragrance.
The process for preparing medicine of the present invention is, such as Fig. 1；A. each crude drug is weighed by recipe ratio；B. by above 8 herbal medicine soak by water three times, wherein: for the first time with 4 times amount water, second time and third time 3 times amount water, every time decoction 2 hours, collecting decoction, filtration；C. discard medicinal residues by medicinal liquid concentrating under reduced pressure, stir, dissolve, cool down, be centrifuged, embedding, steam sterilization, Drug Manufacturing Room be processed into 250ml/ bottled, every bottle of dose, packaging warehouse-in.
Claims (5)
1. treat paralytic ileus, the medicine of promotion abdominal post-operation restoration of gastrointestinal function for one kind, it is characterised in that: it is made up of the crude drug of following weight proportioning: Radix Astragali 15-30 part, Cortex Magnoliae Officinalis 5-15 part, Fructus Aurantii 5-15 part, Radix Glycyrrhizae 15-30 part, Semen Persicae 10-30 part, Rhizoma Chuanxiong 10-30 part, Flos Lonicerae 20-30 part, Herba Taraxaci 20-30 part.
Treatment paralytic ileus the most according to claim 1, the medicine of promotion abdominal post-operation restoration of gastrointestinal function, the most each crude drug ratio range is: Radix Astragali 18-25 part, Cortex Magnoliae Officinalis 6-8 part, Fructus Aurantii 6-12 part, Radix Glycyrrhizae 18-25 part, Semen Persicae 13-25 part, Rhizoma Chuanxiong 13-25 part, Flos Lonicerae 23-28 part, Herba Taraxaci 23-28 part.
Treatment paralytic ileus the most according to claim 1, the medicine of promotion abdominal post-operation restoration of gastrointestinal function, the most each crude drug weight proportion is: the Radix Astragali 20 parts, Cortex Magnoliae Officinalis 10 parts, Fructus Aurantii 10 parts, Radix Glycyrrhizae 20 parts, 15 parts of Semen Persicae, Rhizoma Chuanxiong 20 parts, Flos Lonicerae 25 parts, Herba Taraxaci 25 parts.
4. according to the treatment paralytic ileus described in claim 1 or 2 or 3, the medicine of promotion abdominal post-operation restoration of gastrointestinal function, it is characterised in that described medicine is brown color decoction, slightly Chinese medicine fragrance.
Treatment paralytic ileus the most according to claim 1, the preparation method of medicine of abdominal post-operation restoration of gastrointestinal function of promoting, it is characterised in that: a. weighs each crude drug by recipe ratio；B. by above 8 herbal medicine soak by water three times, wherein: for the first time with 4 times amount water, second time and third time 3 times amount water, every time decoction 2 hours, collecting decoction, filtration；C. discard medicinal residues by medicinal liquid concentrating under reduced pressure, stir, dissolve, cool down, be centrifuged, embedding, steam sterilization packaging warehouse-in.
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| CN201410158645.8A CN103977109B (en) | 2014-04-12 | 2014-04-12 | Drug for treating paralytic ileus and promoting stomach and intestine function recovery after abdominal operation and preparation method thereof |
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| CN101716298B (en) * | 2009-11-06 | 2011-08-10 | 李淑花 | Traditional Chinese medicine preparation for treating surgical intestinal adhesions |
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| 加味厚朴三物汤治疗腹部术后麻痹性肠梗阻36例分析;李慎贤等;《中国老年学杂志》;20070430;第27卷(第8期);第770-772页 * |
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Inventor after: Ai Xiaohui Inventor after: Fu Jiangtao Inventor after: Ning Haitao Inventor after: Huang Xiaoqing Inventor after: Lei Qingliang Inventor after: Xie Gang Inventor after: Shen Xiaoping Inventor after: Luo Bo Inventor after: Zeng Zemin Inventor after: Zhu Wenshuo Inventor after: Zhou Qunxiang Inventor after: Wang Hai Inventor before: Ai Xiaohui Inventor before: Li Xiaojian Inventor before: Zeng Zemin Inventor before: Yin Qingjuan Inventor before: Shen Xiaoping Inventor before: Jin Qingman Inventor before: Huang Xiaoqing |