CN103976916B - Berberis julianae schneid extracting solution and preparation method and application thereof - Google Patents
Berberis julianae schneid extracting solution and preparation method and application thereof Download PDFInfo
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- CN103976916B CN103976916B CN201410239123.0A CN201410239123A CN103976916B CN 103976916 B CN103976916 B CN 103976916B CN 201410239123 A CN201410239123 A CN 201410239123A CN 103976916 B CN103976916 B CN 103976916B
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- barberry
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- 238000002360 preparation method Methods 0.000 title abstract description 14
- 241001407382 Berberis julianae Species 0.000 title abstract 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 30
- 239000000284 extract Substances 0.000 claims description 30
- 229940107588 barberry extract Drugs 0.000 claims description 28
- 239000006071 cream Substances 0.000 claims description 18
- 239000003755 preservative agent Substances 0.000 claims description 17
- 230000002335 preservative effect Effects 0.000 claims description 17
- 235000011187 glycerol Nutrition 0.000 claims description 15
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 12
- 229930182478 glucoside Natural products 0.000 claims description 10
- 150000008131 glucosides Chemical class 0.000 claims description 10
- 229960005323 phenoxyethanol Drugs 0.000 claims description 10
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical group OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 9
- 241001083847 Berberis Species 0.000 claims description 9
- 235000016068 Berberis vulgaris Nutrition 0.000 claims description 9
- 229940082500 cetostearyl alcohol Drugs 0.000 claims description 9
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 9
- 239000002562 thickening agent Substances 0.000 claims description 9
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 8
- 229920005573 silicon-containing polymer Polymers 0.000 claims description 8
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 7
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 7
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 7
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 7
- 239000003963 antioxidant agent Substances 0.000 claims description 6
- 239000003974 emollient agent Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- DWHIUNMOTRUVPG-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCO DWHIUNMOTRUVPG-UHFFFAOYSA-N 0.000 claims description 5
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 claims description 5
- 230000003078 antioxidant effect Effects 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 239000003995 emulsifying agent Substances 0.000 claims description 5
- 229940031674 laureth-7 Drugs 0.000 claims description 5
- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 claims description 5
- 229920002401 polyacrylamide Polymers 0.000 claims description 5
- 229920001285 xanthan gum Polymers 0.000 claims description 5
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical class [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 claims description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- 239000008367 deionised water Substances 0.000 claims description 4
- 229910021641 deionized water Inorganic materials 0.000 claims description 4
- 230000001804 emulsifying effect Effects 0.000 claims description 4
- 229960001295 tocopherol Drugs 0.000 claims description 4
- 229930003799 tocopherol Natural products 0.000 claims description 4
- 235000010384 tocopherol Nutrition 0.000 claims description 4
- 239000011732 tocopherol Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- -1 dimethyl siloxane Chemical class 0.000 claims description 3
- 125000002640 tocopherol group Chemical group 0.000 claims description 3
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 229940119170 jojoba wax Drugs 0.000 claims description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical group CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 2
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 23
- 208000002874 Acne Vulgaris Diseases 0.000 abstract description 19
- 206010000496 acne Diseases 0.000 abstract description 19
- 239000002537 cosmetic Substances 0.000 abstract description 19
- 230000000694 effects Effects 0.000 abstract description 10
- 230000001815 facial effect Effects 0.000 abstract description 10
- 230000028327 secretion Effects 0.000 abstract description 5
- 210000002374 sebum Anatomy 0.000 abstract description 4
- 238000003809 water extraction Methods 0.000 abstract description 4
- 241000894006 Bacteria Species 0.000 abstract description 2
- 206010020649 Hyperkeratosis Diseases 0.000 abstract description 2
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 208000001126 Keratosis Diseases 0.000 abstract description 2
- 210000004027 cell Anatomy 0.000 abstract description 2
- 230000019522 cellular metabolic process Effects 0.000 abstract description 2
- 230000003467 diminishing effect Effects 0.000 abstract description 2
- 210000003780 hair follicle Anatomy 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000008338 local blood flow Effects 0.000 abstract description 2
- 210000004927 skin cell Anatomy 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000000452 restraining effect Effects 0.000 abstract 1
- 210000001732 sebaceous gland Anatomy 0.000 abstract 1
- 239000000686 essence Substances 0.000 description 17
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 14
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 8
- 241000208690 Hamamelis Species 0.000 description 8
- 230000003110 anti-inflammatory effect Effects 0.000 description 8
- 238000000605 extraction Methods 0.000 description 8
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 7
- 229960000458 allantoin Drugs 0.000 description 7
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical group CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 230000035945 sensitivity Effects 0.000 description 6
- 229920001908 Hydrogenated starch hydrolysate Polymers 0.000 description 5
- 241000195493 Cryptophyta Species 0.000 description 4
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 4
- 239000002738 chelating agent Substances 0.000 description 4
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical class CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- 244000144927 Aloe barbadensis Species 0.000 description 3
- 235000002961 Aloe barbadensis Nutrition 0.000 description 3
- 229920002498 Beta-glucan Polymers 0.000 description 3
- 206010013786 Dry skin Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 3
- 229920002125 Sokalan® Polymers 0.000 description 3
- 235000011399 aloe vera Nutrition 0.000 description 3
- 229960001631 carbomer Drugs 0.000 description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 229920000193 polymethacrylate Polymers 0.000 description 3
- 230000005808 skin problem Effects 0.000 description 3
- 235000014676 Phragmites communis Nutrition 0.000 description 2
- 108010009736 Protein Hydrolysates Proteins 0.000 description 2
- 206010070834 Sensitisation Diseases 0.000 description 2
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N dimethylmethane Natural products CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000037336 dry skin Effects 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000001294 propane Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
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- 230000001954 sterilising effect Effects 0.000 description 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 description 1
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 description 1
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 1
- GAOFSPAZESJCOA-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1.OCCOC1=CC=CC=C1 GAOFSPAZESJCOA-UHFFFAOYSA-N 0.000 description 1
- 241000133570 Berberidaceae Species 0.000 description 1
- 241001407326 Berberis brachypoda Species 0.000 description 1
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- 206010012735 Diarrhoea Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
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- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- 229940036350 bisabolol Drugs 0.000 description 1
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
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- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention discloses a berberis julianae schneid extracting solution and a preparation method and application thereof. The berberis julianae schneid extracting solution prepared by means of water extraction has the remarkable effects of resisting bacteria, diminishing inflammation, regulating internal secretion, promoting skin cell metabolism and improving local blood circulation. With the characteristic, the berberis julianae schneid extracting solution has the effects of repairing injured cells, restraining sebum secretion, dredging facial hair follicle and sebaceous gland holes and protecting keratoderma. By applying the berberis julianae schneid extracting solution to cosmetics, the effects of remarkably repairing and protecting sensitive and acne skin are achieved.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of barberry extract solution and preparation method thereof and should
With.
Background technology
With the improvement of people ' s living standards, cosmetics have become necessary article in people's life.But
Quality requirement of the people but for cosmetics is very high, not only requires that effect is good, and requires to make without secondary
With.With the development of cosmetics industry, natural plant kind product due to using safety, action temperature and,
The advantages of effect is obvious and welcome.The plant containing active ingredient is obtained generally by corresponding processing to carry
Thing is taken, and is added in cosmetics.
Plant extracts in current cosmetics, is mostly carried using water extraction, alcohol extracting, ultrasonic wave extraction, microwave
The method such as take and extract gained, extraction process is complicated, by operations such as concentrate dryings, also to add preservative with
Make the shelf-life of extract more permanent.The drawbacks of so bringing, one is waste of resource, in extraction process,
Solution is concentrated, and typically only takes concentration fraction elite out, and most solutions are then thrown away.In fact this
Part solution still be able to can also be reused containing active component, and directly thrown away and resulted in resource
Waste.Another drawback is that addition preservative can no doubt make extract acquisition longer in extract
Shelf-life, but simultaneously also for skin tape carrys out sensitization source.
In addition, acne are a big skin problems of puzzle.Acne are a kind of common hair follicle sebums
Gland inflammatory dermatoses, are mainly in facial area.Because this disease is apt to occur in youth of both sexes, especially Oily
Person, the occurrence factor of acne is varied, but most direct factor is exactly skin sensitivity, clogging of pores.Hair
Hole is obstructed, and the grease of the inside cannot just be secreted, and add now skin sensitivity, cell damage and make skin
The immunity degradation of skin, barrier function is excessively weak, it is difficult to repair skin problem using effective skin care item,
Grease is cumulative, and skin problem is increasingly severe, just forms acne one by one.
Therefore, which kind of plant is selected, how simply, safely, effectively the plant extract is carried out, and will
Sensitive, acne and sore skin is protected in being applied to for its safety in cosmetics, is problem demanding prompt solution.
The content of the invention
Based on this, present invention aim at a kind of barberry extract solution of offer and its preparation method and application.
The concrete technical scheme for solving above-mentioned technical problem is as follows：
A kind of preparation method of barberry extract solution, comprises the following steps：
By barberry drying and crushing, installed with the 800-1000 mesh gauze bags for sterilizing, be placed in vacuum homogenized milk
Change in pot, by the weight of barberry, add the 8-12 times of deionized water measured, extracted in 90-100 DEG C, you can
Barberry extract solution is obtained.
Wherein in some embodiments, the time of the extraction is 20-50min.
Wherein in some embodiments, by barberry drying and crushing, with the 800-1000 mesh gauze bags for sterilizing
Install, be placed in vacuum emulsifying pot, after the completion of extraction, directly take out gauze bag, remaining solution
As barberry extract solution.Due to using vacuum emulsifying pot in the method, its can after the completion of extraction,
Directly other cosmetics are added, Cosmetic Manufacture is carried out, without with special plant extract
Equipment is extracted, and has saved cost；In addition, using the packed barberry powder of gauze, directly by gauze after having extracted
Bag takes out, and without filtering, simplifies extraction process, improves efficiency.
The above method is simple to operation, and Radix Berberidis extract can show use of withdrawing deposit, and is not required to add preservative, significantly
Reduce the sensitization source to skin.In cosmetic formulations, preservative is inherently added with, by extract of the present invention
Now carry and adding, it is to avoid because of placement produce spoilage problems.
Barberry extract solution obtained by the above method is being prepared with reparation and protection sensitivity, acne and sore skin
Application in the cosmetics of skin effect.
Wherein in some embodiments, the content of barberry extract solution is 58-95wt% in the cosmetics.
Wherein in some embodiments, the cosmetics are nourishing cream, essence or mask.
The present invention provides a kind of nourishing cream, and the nourishing cream includes the component of following weight percentage：
Emulsifying agent：3.5-6.3wt%,
Emollient：5-10wt%,
Antioxidant：0.2-0.8wt%,
NMF：5-15wt%,
Thickener：0.05-0.15wt%,
Preservative：0.3-0.7wt%,
Barberry extract solution obtained in above-mentioned preparation method：Surplus,
The emulsifying agent is cetostearyl alcohol/cetearyl glucoside, cetostearyl alcohol, stearine
/ PEG-100 stearates, polyacrylamide/C13-14 isoparaffins/laureth -7 or methyl
At least one in sesquistearate；
The emollient be ring five dimethyl silicone polymer/cyclohexasiloxane, dimethyl silicone polymer, octanoic acid/
At least one in Triglyceride DDD or hydrogenated jojoba oil；
The antioxidant is tocopherol or at least one being confused in the extract that changes；
The NMF is at least in propane diols, glycerine, Sodium Hyaluronate, FOS or sorbierite
Kind；
The thickener is at least one in xanthans or sodium carboxymethylcellulose；
The preservative is Phenoxyethanol/Sensiva SC50.
Wherein in some embodiments, the nourishing cream includes the component of following weight percentage：
Emulsifying agent：4.9-6.3wt%,
Emollient：6.4-7.6wt%,
Antioxidant：0.4-0.6wt%,
NMF：8-12.15wt%,
Thickener：0.09-0.11wt%,
Preservative：0.4-0.6wt%,
Barberry extract solution obtained in above-mentioned preparation method：Surplus,
The emulsifying agent is cetostearyl alcohol/cetearyl glucoside, cetostearyl alcohol, stearine
In/PEG-100 stearates or polyacrylamide/C13-14 isoparaffins/laureth -7 at least one
Kind；
The emollient be ring five dimethyl silicone polymer/cyclohexasiloxane, dimethyl silicone polymer or octanoic acid/
At least one in Triglyceride DDD；
The antioxidant is tocopherol；
The NMF is at least one in propane diols, glycerine, Sodium Hyaluronate or FOS；
The thickener is xanthans；
The preservative is Phenoxyethanol/Sensiva SC50.
Wherein in some embodiments, the nourishing cream includes the component of following weight percentage：
Cetostearyl alcohol/cetearyl glucoside：2.3-2.7wt%,
Cetostearyl alcohol：1-1.4wt%,
Stearine/PEG-100 stearates：1-1.4wt%,
Ring five dimethyl silicone polymer/cyclohexasiloxane：1.8-2.2wt%,
Dimethyl silicone polymer：1.8-2.2wt%,
Caprylic/capric triglyceride：2.8-3.2wt%,
Tocopherol：0.4-0.6wt%,
Propane diols：4-6wt%,
Glycerine：4-6wt%,
Xanthans：0.09-0.11wt%,
Sodium Hyaluronate：0.015-0.025wt%,
Polyacrylamide/C13-14 isoparaffins/laureth -7：0.6-0.8wt%,
Phenoxyethanol/Sensiva SC50：0.4-0.6wt%,
FOS：0.08-0.11wt%,
Above-mentioned barberry extract solution：Surplus.
The present invention also provides a kind of essence, and the essence includes the component of following weight percentage：
Chelating agent：0.01-0.1wt%,
NMF：5-18wt%,
Antiinflammatory：0.05-2.5wt%,
Preservative：0.3-0.66wt%,
Radix Berberidis extract obtained in above-mentioned preparation method：Surplus；
The chelating agent is at least one in EDTA- disodiums or Etidronic Acid；
The NMF is glycerine, propane diols, Fructus Hordei Germinatus oligose base glucosides/hydrogenated starch hydrolysate, Curacao reed
At least one in luxuriant growth leaf extract or PEG400；
The antiinflammatory is in allantoin, hamamelis extract, dipotassium glycyrrhizinate or pot marigold extract
At least one；
The preservative is Phenoxyethanol/Sensiva SC50.
Wherein in some embodiments, the essence includes the component of following weight percentage：
Chelating agent：0.01-0.025wt%,
NMF：10-15.5wt%,
Antiinflammatory：1.9-2.4wt%,
Preservative：0.54-0.66wt%,
Radix Berberidis extract obtained in above-mentioned preparation method：Surplus；
The chelating agent is EDTA- disodiums；
The NMF is glycerine, propane diols, Fructus Hordei Germinatus oligose base glucosides/hydrogenated starch hydrolysate or Curacao reed
At least one in luxuriant growth leaf extract；
The antiinflammatory is at least one in allantoin, hamamelis extract or dipotassium glycyrrhizinate；
The preservative is in Phenoxyethanol/Sensiva SC50.
Wherein in some embodiments, the essence includes the component of following weight percentage：
EDTA- disodiums：0.018-0.022wt%,
Glycerine：4-6wt%,
Propane diols：4-6wt%,
Allantoin：0.09-0.11wt%,
Methyl hydroxybenzoate：0.09-0.11wt%,
Hamamelis extract：1.8-2.2wt%,
Dipotassium glycyrrhizinate：0.045-0.055wt%,
Fructus Hordei Germinatus oligose base glucosides/hydrogenated starch hydrolysate：0.9-1.1wt%,
Aloe barbadensis Miller leaf extract：1.8-2.2wt%,
Phenoxyethanol/Sensiva SC50：0.45-0.55,
Above-mentioned barberry extract solution：Surplus.
The present invention also provides a kind of mask, and the mask includes the component of following weight percentage：
NMF：5-35wt%,
Thickener：0.05-0.3wt%,
Antiinflammatory：2.5-5.5wt%,
PH adjusting agent：0.04-0.08wt%,
Preservative：0.2-0.6wt%,
Above-mentioned Radix Berberidis extract：Surplus；
The NMF be glycerine, butanediol, propane diols, Sodium Hyaluronate, glycerine polymethacrylates/
At least one in propane diols, Ovshinsky marine algae extract, beta glucan or FOS；
The thickener is at least one in hydroxyethyl cellulose, Carbomer or xanthans；
The antiinflammatory is at least one in allantoin, hamamelis extract or bisabolol；
The pH adjusting agent is at least one in triethanolamine, potassium hydroxide or NaOH；
The preservative is at least in 1,2- hexylene glycols/pungent glycol or Phenoxyethanol/Sensiva SC50
Kind.
Wherein in some embodiments, the mask includes the component of following weight percentage：
NMF：21.5-32.3wt%,
Thickener：0.14-0.26wt%,
Antiinflammatory：3.1-5.5wt%,
PH adjusting agent：0.05-0.07wt%,
Preservative：0.4-0.6wt%,
Above-mentioned Radix Berberidis extract：Surplus；
The NMF be glycerine, butanediol, propane diols, Sodium Hyaluronate, glycerine polymethacrylates/
At least one in propane diols, Ovshinsky marine algae extract or beta glucan；
The thickener is at least one in hydroxyethyl cellulose or Carbomer；
The antiinflammatory is at least one in allantoin or hamamelis extract；
The pH adjusting agent is at least one in potassium hydroxide or NaOH；
The preservative is 1,2- hexylene glycols/pungent glycol.
Wherein in some embodiments, the mask includes the component of following weight percentage：
Glycerine：4-6wt%,
Butanediol：4-6wt%,
Propane diols：2-4wt%,
Hydroxyethyl cellulose：0.04-0.06wt%,
Sodium Hyaluronate：0.025-0.035wt%,
Carbomer：0.1-0.2wt%,
Allantoin：0.1-0.2wt%,
Beta glucan：0.8-1.2wt%,
Glycerine polymethacrylates/propane diols：7-9wt%,
Ovshinsky marine algae extract：4-6wt%,
Hamamelis extract：3-5wt%,
Potassium hydroxide：0.05-0.07wt%,
1,2- hexylene glycols/pungent glycol：0.4-0.6wt%,
Above-mentioned barberry extract solution：Surplus.
A kind of barberry extract solution of the present invention and its preparation method and application has advantages below and beneficial effect
Really：
The present invention is drawn in optimum process through the substantial amounts of experiment of inventor and research --- it is obtained under water extraction
Barberry extract solution, it has significant inhibiting bacteria and diminishing inflammation, regulation endocrine, promotes skin cell metabolism
And improve the effect of local blood circulation, this characteristic causes that barberry extract solution possesses reparation damaged cell,
Suppress sebum secretion, the effect of dredging facial follicles, sebum glandular orifice and protection keratoderma is answered
For having functions that significant reparation and protection sensitivity, acne and sore skin in cosmetics.
Specific embodiment
Barberry of the present invention is the root skin or stem that Berberidaceae plant pierces black pearl, berberis brachypoda Maxim, black stone pearl etc.
Skin, cold in nature, slight bitter is nontoxic, with heat-clearing；Eliminating dampness；The effect of purging intense heat and detonicating.《Traditional Chinese Medicine in Sichuan will》："
It is clearing heat and detoxicating, antiphlogistic antibacterial.Control hot eyes, dysentery characterized by blood in the stool, haematemesis internal lesion caused by overexertion, abscess of throat, diarrhoea, dentalgia, ear
Pained, traumatic injury is red and swollen.", barberry is obtained barberry extract solution by the present invention through water extraction, is used it for
Prepare with reparation and protection sensitivity, acne and sore cosmetics for skin.
Below with reference to specific embodiment, the present invention will be further described.
In following embodiments, the hamamelis extract purchased from Xi'an Sen Ran bioengineering Co., Ltd,
Aloe barbadensis Miller leaf extract is purchased from Tianfeng Biological Science ＆ Technology Co., Ltd., Xi'an, Ovshinsky marine algae extract purchased from west
An Ruiying bio tech ltd, the equal commercially available prod of other raw materials.
Used Components Name is international cosmetic raw material name (International in following examples
Nomenclature Cosmetic Ingredient, INCI) defined title, such as Phenoxyethanol/second
Base hexyl glycerine, ring five dimethyl silicone polymer/cyclohexasiloxane, stearine/PEG-100 are stearic
Acid esters, cetostearyl alcohol/cetearyl glucoside, caprylic/capric triglyceride, polyacrylamide/C13-14
Isoparaffin/laureth -7, Fructus Hordei Germinatus oligose base glucosides/hydrogenated starch hydrolysate, glycerine polymethyl
Acid esters/propane diols, 1,2- hexylene glycols/pungent glycol.
The nourishing cream of embodiment 1
Containing barberry extract solution in nourishing cream described in the present embodiment, the preparation method of the barberry extract solution,
Comprise the following steps：1 kilogram of barberry is cleaned, is dried, drying and crushing to 100 mesh, with what is sterilized
1000 mesh gauze bags are installed, and are placed in vacuum emulsifying pot, 12 kilograms of deionized water are added, in 100 DEG C
Extraction 50min, gauze bag is taken out, and remaining solution obtains final product barberry extract solution.
The component and content of the nourishing cream are shown in Table 1：
The component and content of the nourishing cream of table 1
The essence of embodiment 2
Containing barberry extract solution in essence described in the present embodiment, the preparation method of the barberry extract solution,
With reference to embodiment 1.
The component and content of the essence are shown in Table 2：
The component and content of the essence of table 2
The mask of embodiment 3
Containing barberry extract solution in mask described in the present embodiment, the preparation method of the barberry extract solution,
With reference to embodiment 1.
The component and content of the mask are shown in Table 3：
The component and content of the mask of table 3
The nourishing cream of comparative example 1
The component and content of the nourishing cream are shown in Table 4：
The component and content of the nourishing cream of table 4
The essence of comparative example 2
The component and content of the essence are shown in Table 5：
The component and content of the essence of table 5
| Composition | Percentage by weight (wt%) |
| Deionized water | Surplus |
| EDTA- disodiums | 0.02 |
| Glycerine | 5 |
| Butanediol | 5 |
| Allantoin | 0.1 |
| Methyl hydroxybenzoate | 0.1 |
| Hamamelis extract | 2 |
| Dipotassium glycyrrhizinate | 0.05 |
| Fructus Hordei Germinatus oligose base glucosides/hydrogenated starch hydrolysate | 1 |
| Aloe barbadensis Miller leaf extract | 2 |
| Phenoxyethanol/Sensiva SC50 | 0.5 |
| It is total | 100 |
The mask of comparative example 3
The component and content of the mask are shown in Table 6：
The component and content of the mask of table 6
The efficacy assessments of embodiment 4
First, experiment purpose
Reparation and protection sensitivity, powder by cosmetics obtained in comparative analysis evaluation the various embodiments described above
Pierce the effect of dark sore skin.
2nd, experimental technique
This experiment is divided into experimental group and control group, wherein, experimental group is divided into：Embodiment 1- nourishing cream, implementation
Example 2- essences, embodiment 3- facial masks；Control group be comparative example 1- nourishing cream, comparative example 2- essences,
It is comparative example 3- facial masks, a certain commercially available with repairing and protection is sensitive, acne and sore skin essence.
Collection is sensitive, 200 volunteers of acne and sore skin tried out above-mentioned each product after 28 days, observes result.
Wherein, the people of women 120, the people of male 80, max age 30 years old, minimal ages 15 years old, average age 22
Year.
Sensitive, the acne and sore skin shows as：Facial redness, acne and sore, acne print, skin are done
Dry, pore is thick or skin oil and fat is secreted.
3rd, experimental result
Result is referring to table 7.
The efficacy outcomes table of the experimental group of table 7 and control group
As known from Table 7：Each product of control group is comparative example 1- nourishing cream, comparative example 2- essences, comparative example
3- facial masks, a certain commercially available essence and each product embodiments 1- nourishing cream of experimental group, embodiment 2- essences,
Embodiment 3- facial masks are thick to facial redness, acne and sore, acne print, dry skin, pore or skin oil and fat
Secretion has different degrees of improvement, from experimental data as can be seen that in experimental group each product to it is facial red and swollen,
Acne and sore, acne print, dry skin, pore be thick or the improvement degree of skin oil and fat secretion is substantially than control
The improvement degree of each product is high in group, it follows that the cosmetics containing barberry extract solution have significantly
Reparation and protection is sensitive, effect of acne and sore skin.
Embodiment described above only expresses several embodiments of the invention, and its description is more specific and detailed,
But therefore can not be interpreted as the limitation to the scope of the claims of the present invention.It should be pointed out that for this area
Those of ordinary skill for, without departing from the inventive concept of the premise, can also make it is some deformation and
Improve, these belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be with appended
Claim is defined.
Claims (1)
1. a kind of nourishing cream, it is characterised in that the nourishing cream includes the component of following weight percentage:Breast
Agent:3.5-6.3wt%, emollient:5-10wt%, antioxidant:0.2-0.8wt%, NMF:5-15wt%, increases
Thick dose:0.05-0.15wt%, preservative:0.3-0.7wt%, barberry extract solution surplus；
The emulsifying agent is cetostearyl alcohol/cetearyl glucoside, cetostearyl alcohol, stearine
/ PEG-100 stearates, polyacrylamide/C13-14 isoparaffins/laureth -7 or methyl times
At least one in semi-solid fat acid esters；The emollient is ring five dimethyl silicone polymer/cyclohexasiloxane, gathers
At least one in dimethyl siloxane, caprylic/capric triglyceride or hydrogenated jojoba oil；It is described anti-oxidant
Agent is tocopherol；The NMF is in propane diols, glycerine, Sodium Hyaluronate, FOS or sorbierite
At least one；The thickener is at least one in xanthans or sodium carboxymethylcellulose；It is described anti-
Rotten agent is Phenoxyethanol/Sensiva SC50；
The barberry extract solution is prepared using following methods：By barberry drying and crushing, with what is sterilized
800-1000 mesh gauze bags are installed, and are placed in vacuum emulsifying pot, by the weight of barberry, add 8-12
The deionized water of amount, extracts in 90-100 DEG C again, you can barberry extract solution is obtained.
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| CN104170840B (en) * | 2014-09-06 | 2016-01-27 | 许伟琦 | A kind of sustained-release tree-peony transplantation rooting agent composition |
| CN105616221A (en) * | 2014-10-31 | 2016-06-01 | 沈阳市坤美惜美容用品有限公司 | Acne-removal cosmetic and preparation method thereof |
| CN105411964A (en) * | 2016-01-05 | 2016-03-23 | 广州千百度化妆品有限公司 | Traditional Chinese medicine composition and preparing method and application thereof |
| CN105434286A (en) * | 2016-01-05 | 2016-03-30 | 广州千百度化妆品有限公司 | Plant composition and preparation method and application thereof |
| CN105560864A (en) * | 2016-01-22 | 2016-05-11 | 顾志情 | Traditional Chinese medicine composition for treating acne and preparation method and application thereof |
| CN105662968A (en) * | 2016-03-02 | 2016-06-15 | 广州千百度化妆品有限公司 | Face cleanser for removing acne marks |
| CN105640843A (en) * | 2016-03-02 | 2016-06-08 | 广州千百度化妆品有限公司 | Traditional Chinese medicine composition capable of removing acne and application thereof |
| CN106726987A (en) * | 2016-12-28 | 2017-05-31 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of inhibiting bacteria and diminishing inflammation composition and its application |
| CN106667847A (en) * | 2017-02-22 | 2017-05-17 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Magnetic graphene composite material mask rich in hydrogen water |
| CN111617002A (en) * | 2020-06-24 | 2020-09-04 | 玮格沃德贸易有限公司 | Moisturizing, brightening and firming mask |
| CN112915119B (en) * | 2021-03-20 | 2022-05-03 | 杜锡萍 | Traditional Chinese medicine composition for treating acne, preparation method thereof and mask paste containing composition |
| CN114748376A (en) * | 2021-06-10 | 2022-07-15 | 广州富妆生物科技有限公司 | Moisturizing and high-moisture-retention moisturizing cream and preparation method thereof |
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