CN103948879A - Traditional Chinese medicinal particles for treating viral hepatitis and preparation method thereof - Google Patents
Traditional Chinese medicinal particles for treating viral hepatitis and preparation method thereof Download PDFInfo
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- CN103948879A CN103948879A CN201410221152.4A CN201410221152A CN103948879A CN 103948879 A CN103948879 A CN 103948879A CN 201410221152 A CN201410221152 A CN 201410221152A CN 103948879 A CN103948879 A CN 103948879A
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Abstract
The invention discloses traditional Chinese medicinal particles for treating viral hepatitis and a preparation method thereof. The traditional Chinese medicinal particles for treating the viral hepatitis are prepared from the following raw materials in parts by weight: 15-20 parts of codonopsis pilosula, 10-15 parts of corn stigma, 8-12 parts of poria cocos, 18-24 parts of microcos paniculata, 5-10 parts of madder, 10-15 parts of radix bupleuri, 16-22 parts of curcuma aromatica, 12-16 parts of white atractylodes rhizome, 10-15 parts of Chinese lobelia, 8-12 parts of oriental wormwood, 5-10 parts of rhizoma polygonatum, 10-15 parts of sweet potato leaves, 7-11 parts of shaddock peel, 14-18 parts of inula flower, 9-13 parts of lychee seed, 4-8 parts of rhizoma sparganic, 6-12 parts of curcuma zedoary, 10-15 parts of flos mume, 5-10 parts of pawpaw seed, 8-12 parts of dandelion, 15-20 parts of Chinese angelica and 12-18 parts of serrate rabdosia herb. The traditional Chinese medicinal particles disclosed by the invention have the effects of clearing heat, promoting diuresis, protecting liver, tonifying spleen, regulating vital energy, promoting appetite, activating blood and dissolving stasis, can quickly restore functions of the liver and has an obvious effect on treatment of the viral hepatitis, the total effective rate is more than 96%, curative ratio is more than 88%, treatment course is short, a treatment course is short, no adverse effect is produced, and toxic and side effects are not produced, so that the traditional Chinese medicinal particles disclosed by the invention are safe and reliable.
Description
Technical field
The present invention relates to a kind of Chinese medicinal granule and preparation method thereof, be specifically related to a kind of Chinese medicinal granule for the treatment of viral hepatitis and preparation method thereof.
Background technology
Viral hepatitis be caused by hepatitis virus taking inflammation for a long time with downright bad pathological changes as one group of main infectious disease, be legal Category B notifiable disease, have that infectiousness is strong, complicated, popular wide general, the sickness rate high in route of transmission.At present fixed have five types of A type, B-mode, the third type, fourth type and hepatitis E, clinical in to feel sick, vomit, to detest oil, weak, loss of appetite, hepatomegaly, abnormal liver function as main manifestations, can there is jaundice in some patients were, can also show as symptomless infection or self limiting inapparent infection, some patient also can show as chronic hepatitis or liver failure.The shortcomings such as although the Chinese medicine preparation of existing treatment viral hepatitis is of a great variety, and great majority exist uncertain therapeutic efficacy to cut, and cure rate is low.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of Chinese medicinal granule for the treatment of viral hepatitis and preparation method thereof is provided, this Chinese medicinal granule is evident in efficacy, short treating period, cure rate are high, has no adverse reaction.
The technical solution used in the present invention is as follows:
Treat a Chinese medicinal granule for viral hepatitis, made by the raw material of following weight portion: Radix Codonopsis 15-20, Stigma Maydis 10-15, Poria 8-12, Folium Microcoris paniculatae 18-24, Radix Rubiae 5-10, Radix Bupleuri 10-15, Radix Curcumae 16-22, Rhizoma Atractylodis Macrocephalae 12-16, Herba Lobeliae Chinensis 10-15, Herba Artemisiae Scopariae 8-12, Rhizoma Polygonati 5-10, Radix Pachyrhizi Erosi leaf 10-15, pomelo peel 7-11, Flos Inulae 14-18, Semen Litchi 9-13, Rhizoma Sparganii 4-8, Rhizoma Curcumae 6-12, Flos Pruni mume 10-15, Semen Fructus Chaenomelis 5-10, Herba Taraxaci 8-12, Radix Angelicae Sinensis 15-20, Herba Rabdosiae Lophanthoidis 12-18.
Preferably, treat a Chinese medicinal granule for viral hepatitis, made by the raw material of following weight portion: Radix Codonopsis 18, Stigma Maydis 10, Poria 10, Folium Microcoris paniculatae 22, Radix Rubiae 8, Radix Bupleuri 15, Radix Curcumae 18, the Rhizoma Atractylodis Macrocephalae 14, Herba Lobeliae Chinensis 12, Herba Artemisiae Scopariae 10, Rhizoma Polygonati 7, Radix Pachyrhizi Erosi leaf 12, pomelo peel 9, Flos Inulae 15, Semen Litchi 11, Rhizoma Sparganii 6, Rhizoma Curcumae 8, Flos Pruni mume 10, Semen Fructus Chaenomelis 8, Herba Taraxaci 10, Radix Angelicae Sinensis 18, Herba Rabdosiae Lophanthoidis 16.
The present invention treats the preparation method of the Chinese medicinal granule of viral hepatitis, comprises the following steps:
(1) get Radix Codonopsis, Poria, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, Semen Litchi, Semen Fructus Chaenomelis, Radix Angelicae Sinensis mix homogeneously, pulverize, cross 100-150 mesh sieve, stand-by;
(2) raw material mix homogeneously under remainder, adds 5-10 times of water gaging, and micro-boiling decocts 1-2h, filters, and filtering residue adds 4-8 times of water gaging again, and micro-boiling decocts 0.5-1h, filters, and merging filtrate, is concentrated into the thick paste that relative density is 1.32-1.36, stand-by;
(3) thick paste that powder step (1) being made and step (2) make stirs, and granulates, dry.
Stigma Maydis, Herba Lobeliae Chinensis, Herba Artemisiae Scopariae in above-mentioned side: inducing diuresis to remove edema, suppressing the hyperactive liver function of gallbladder promoting, heat-clearing and toxic substances removing; The Rhizoma Atractylodis Macrocephalae, Poria: invigorating spleen to remove dampness; Radix Bupleuri, Radix Curcumae, Semen Litchi: depressed liver-energy dispersing and QI regulating; Folium Microcoris paniculatae, pomelo peel, Radix Pachyrhizi Erosi leaf: circulation of qi promoting appetizing, the spleen invigorating of invigorating blood circulation, dyspepsia and intestinal stasis relieving; Radix Angelicae Sinensis, Radix Rubiae: promoting blood circulation and cooling blood; Herba Lobeliae Chinensis, Herba Taraxaci: inducing diuresis to remove edema, heat-clearing and toxic substances removing; Rhizoma Polygonati, Radix Codonopsis: boosting qi and nourishing yin, invigorating the spleen and benefiting QI; Flos Inulae: with suppressing the hyperactive liver and easing the stomach, stopping nausea and vomiting by lowering the adverse flow of QI; Herba Rabdosiae Lophanthoidis: clearing away heat-damp and promoting diuresis, jaundice eliminating damp eliminating; Rhizoma Sparganii, Rhizoma Curcumae: removing blood stasis, circulation of qi promoting removing food stagnancy; Flos Pruni mume: soothing liver-QI stomach function regulating, regulating the flow of Qi and the middle Jiao; Semen Fructus Chaenomelis: hepatoprotective, antiinflammatory are antibacterial.
Beneficial effect of the present invention:
The all medicines of Chinese medicinal granule of the present invention share has clearing away heat-damp and promoting diuresis, protect the liver spleen invigorating, the appetizing of regulating the flow of vital energy, the effects such as blood circulation promoting and blood stasis dispelling, quick-recovery liver function soon, have remarkable result for treatment viral hepatitis, total effective rate reaches more than 96%, and cure rate reaches more than 88%, and short treating period, have no adverse reaction, have no side effect, safe and reliable.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicinal granule for viral hepatitis, made by the raw material of following weight (g): Radix Codonopsis 15, Stigma Maydis 10, Poria 8, Folium Microcoris paniculatae 18, Radix Rubiae 5, Radix Bupleuri 10, Radix Curcumae 16, the Rhizoma Atractylodis Macrocephalae 12, Herba Lobeliae Chinensis 10, Herba Artemisiae Scopariae 8, Rhizoma Polygonati 5, Radix Pachyrhizi Erosi leaf 10, pomelo peel 7, Flos Inulae 14, Semen Litchi 9, Rhizoma Sparganii 4, Rhizoma Curcumae 6, Flos Pruni mume 10, Semen Fructus Chaenomelis 5, Herba Taraxaci 8, Radix Angelicae Sinensis 15, Herba Rabdosiae Lophanthoidis 12.
A preparation method for the treatment of the Chinese medicinal granule of viral hepatitis, comprises the following steps:
(1) get Radix Codonopsis, Poria, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, Semen Litchi, Semen Fructus Chaenomelis, Radix Angelicae Sinensis mix homogeneously, pulverize, cross 150 mesh sieves, stand-by;
(2) raw material mix homogeneously under remainder, adds 8 times of water gagings, and micro-boiling decocts 1.5h, filters, and filtering residue adds 6 times of water gagings again, and micro-boiling decocts 1h, filters, and merging filtrate, is concentrated into relative density and is 1.35 thick paste, stand-by;
(3) thick paste that powder step (1) being made and step (2) make stirs, and granulates, dry.
Embodiment 2
Treat a Chinese medicinal granule for viral hepatitis, made by the raw material of following weight (g): Radix Codonopsis 18, Stigma Maydis 10, Poria 10, Folium Microcoris paniculatae 22, Radix Rubiae 8, Radix Bupleuri 15, Radix Curcumae 18, the Rhizoma Atractylodis Macrocephalae 14, Herba Lobeliae Chinensis 12, Herba Artemisiae Scopariae 10, Rhizoma Polygonati 7, Radix Pachyrhizi Erosi leaf 12, pomelo peel 9, Flos Inulae 15, Semen Litchi 11, Rhizoma Sparganii 6, Rhizoma Curcumae 8, Flos Pruni mume 10, Semen Fructus Chaenomelis 8, Herba Taraxaci 10, Radix Angelicae Sinensis 18, Herba Rabdosiae Lophanthoidis 16.
Preparation method is with embodiment 1.
Embodiment 3
Treat a Chinese medicinal granule for viral hepatitis, made by the raw material of following weight (g): Radix Codonopsis 20, Stigma Maydis 15, Poria 12, Folium Microcoris paniculatae 24, Radix Rubiae 10, Radix Bupleuri 15, Radix Curcumae 22, the Rhizoma Atractylodis Macrocephalae 16, Herba Lobeliae Chinensis 15, Herba Artemisiae Scopariae 12, Rhizoma Polygonati 10, Radix Pachyrhizi Erosi leaf 15, pomelo peel 11, Flos Inulae 18, Semen Litchi 13, Rhizoma Sparganii 8, Rhizoma Curcumae 12, Flos Pruni mume 15, Semen Fructus Chaenomelis 10, Herba Taraxaci 12, Radix Angelicae Sinensis 20, Herba Rabdosiae Lophanthoidis 18.
Preparation method is with embodiment 1.
model case
Case 1: Zhang, man, 58 years old, first visit on April 30 in 2010.Main suit: yellow urine, continue to increase the weight of nearly surrounding.Patient finds yellow urine on April 4th, 2010.April 8 Nikkei examination in hospital abnormal liver function, serum T BIL99.3umol/L, ALT1770.4u/L, HBsAg (-); Give the intravenous drips such as diammonium glycyrrhizinate, motassium magnessium aspartate, Radix Salviae Miltiorrhizae, six-aminoacid, yellow urine is more and more heavier.29 daily inspections: HAVIgm (-), five indexes of hepatitis b inspection (-), HEVIgm (+), intends examining hepatitis E.Continue to rise according to the nearly surrounding jaundice of patient, but symptom of digestive tract is lighter, does not find again occupying lesion, with reference to every inspection.Tcm diagnosis: jaundice.Western medicine diagnose: viral hepatitis, penta type, acute silt gallbladder type.Control with heat-clearing and toxic substances removing removing heat from blood and promoting blood circulation.Fang Yong: from virusoid hepatitis side plus-minus, coordinate the intravenous drips such as motassium magnessium aspartate, QINGKAILING, potenlin, compound Salviae Miltiorrhizae, 3AA.Check on May 2: patient's jaundice continues rise (serum T BIL408.0umol/L), AFP (+).Check on May 6: patient's jaundice decline (serum T BIL257.0umol/L).Check on May 9: patient's jaundice continues decline (serum T BIL216.4umol/L).Check on May 13: patients serum TBIL84.6umol/L.May 14, patient left hospital, Chinese medicine 1 dose of continuous using every day after leaving hospital.Check on May 25: patients serum TBIL62.4umol/L.Check on June 12: patient's total bilirubin is recovered normal (TBIL13.6umol/L).JIUYUE check on the 19th: liver function is normal, and anti-HEVIgm is normal.Hepatitis E is cured.
Case 2: Korea Spro, female, 27 years old, first visit on October 11 in 2010.Main suit: appearance is all yellow, abdominal distention discomfort, detests greasyly, and heating is outstanding, and body is tired, anorexia, dark coloured urine Huang.Red tongue, the micro-Huang of greasy fur, rolling pulse.Show through examination in hospital liver function: glutamate pyruvate transaminase 438U/L, glutamic oxaloacetic transaminase, GOT 345U/L, bilirubin direct 85umol/L, total bilirubin 150umol/L.Doctor trained in Western medicine is examined as icterohepatitis, and the traditional Chinese medical science is examined as jaundice, and card belongs to YANG jaundice, controls with eliminating damp-heat.Fang Yong: add and subtract from virusoid hepatitis side.Take after 7 doses, check on October 18: appetite increases, and gastral cavity completely subtracts, still abdominal distention, hypochondriac pain, look into liver function: glutamate pyruvate transaminase: 256U/L, bilirubin direct: 55umol/L, total bilirubin 100umol/L, continues to take 7 doses, check on October 18: all diseases alleviate.Continue and take 5 doses again, order malaise symptoms disappears, and looks into liver function normal, recovery from illness.
Case 3: Liu so-and-so, man, 39 years old, first visit on July 11 in 2011, patient is onset before 1 month, nausea and vomiting, poor appetite lack of appetite, fatigue and weakness, is gradually shown in jaundice, before first quarter moon, remove hospital admission, liver function test is obviously abnormal on inspection: HBsAg (+), HBcAg (+), HBeAb (+), TBIL:86Umol/L, IBIL65Umol/L, ALT:165Utool/L, ALP:126Umol/L, GGT:78Umol/L.Western medicine diagnose is: acute type B viral hepatitis.The traditional Chinese medical science is examined as jaundice, because invading taste in epidemic disease caused by damp-heat pathogen poison, injures liver and gall, fills the air three warmers, controls with heat-clearing and toxic substances removing dampness removing jaundice eliminating, Fang Yong: from virusoid hepatitis side plus-minus, and coordinate doctor trained in Western medicine supporting treatment.Take after 8 doses, the state of an illness gets better every day, and jaundice is gradually moved back, receive food can, liver function test result is constantly improved.Continuous take 12 doses after malaise symptoms disappear, check liver function is normal, recovery from illness is left hospital.
Claims (3)
1. treat the Chinese medicinal granule of viral hepatitis for one kind, it is characterized in that, made by the raw material of following weight portion: Radix Codonopsis 15-20, Stigma Maydis 10-15, Poria 8-12, Folium Microcoris paniculatae 18-24, Radix Rubiae 5-10, Radix Bupleuri 10-15, Radix Curcumae 16-22, Rhizoma Atractylodis Macrocephalae 12-16, Herba Lobeliae Chinensis 10-15, Herba Artemisiae Scopariae 8-12, Rhizoma Polygonati 5-10, Radix Pachyrhizi Erosi leaf 10-15, pomelo peel 7-11, Flos Inulae 14-18, Semen Litchi 9-13, Rhizoma Sparganii 4-8, Rhizoma Curcumae 6-12, Flos Pruni mume 10-15, Semen Fructus Chaenomelis 5-10, Herba Taraxaci 8-12, Radix Angelicae Sinensis 15-20, Herba Rabdosiae Lophanthoidis 12-18.
2. a kind of Chinese medicinal granule for the treatment of viral hepatitis according to claim 1, it is characterized in that, made by the raw material of following weight portion: Radix Codonopsis 18, Stigma Maydis 10, Poria 10, Folium Microcoris paniculatae 22, Radix Rubiae 8, Radix Bupleuri 15, Radix Curcumae 18, the Rhizoma Atractylodis Macrocephalae 14, Herba Lobeliae Chinensis 12, Herba Artemisiae Scopariae 10, Rhizoma Polygonati 7, Radix Pachyrhizi Erosi leaf 12, pomelo peel 9, Flos Inulae 15, Semen Litchi 11, Rhizoma Sparganii 6, Rhizoma Curcumae 8, Flos Pruni mume 10, Semen Fructus Chaenomelis 8, Herba Taraxaci 10, Radix Angelicae Sinensis 18, Herba Rabdosiae Lophanthoidis 16.
3. the preparation method of the Chinese medicinal granule for the treatment of viral hepatitis as claimed in claim 1 or 2, is characterized in that comprising the following steps:
Get Radix Codonopsis, Poria, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Rhizoma Polygonati, Semen Litchi, Semen Fructus Chaenomelis, Radix Angelicae Sinensis mix homogeneously, pulverize, cross 100-150 mesh sieve, stand-by;
Raw material mix homogeneously under remainder, adds 5-10 times of water gaging, and micro-boiling decocts 1-2h, filters, and filtering residue adds 4-8 times of water gaging again, and micro-boiling decocts 0.5-1h, filters, and merging filtrate, is concentrated into the thick paste that relative density is 1.32-1.36, stand-by;
The thick paste that the powder that step (1) is made and step (2) make stirs, and granulates, dry.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106389655A (en) * | 2016-11-22 | 2017-02-15 | 广西大学 | Drug for treating HepatitisBHBeAg of HBV (hepatitis B virus) and preparation method of drug |
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Non-Patent Citations (1)
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| 吕文良: "《名老中医肝病治验录》", 31 March 2012 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106389655A (en) * | 2016-11-22 | 2017-02-15 | 广西大学 | Drug for treating HepatitisBHBeAg of HBV (hepatitis B virus) and preparation method of drug |
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Application publication date: 20140730 |