CN103948663A - Traditional Chinese medicine composition as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine composition as well as preparation method and application thereof Download PDFInfo
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- CN103948663A CN103948663A CN201410205687.2A CN201410205687A CN103948663A CN 103948663 A CN103948663 A CN 103948663A CN 201410205687 A CN201410205687 A CN 201410205687A CN 103948663 A CN103948663 A CN 103948663A
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Abstract
The invention relates to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 160 to 170 parts of cordyceps militaris, 70 to 80 parts of lumbricus, 50 to 55 parts of flowers carthami, 30 to 40 parts of frankincense, 50 to 55 parts of centipede, and 50 to 60 parts of rhodiola rosea. The traditional Chinese medicine composition comprises cordyceps militaris, lumbricus, flowers carthami, frankincense, centipede, and rhodiola rosea; the active ingredients of the medicines above supplement each other and actively coordinate, so that the traditional Chinese medicine composition prepared thereby has small side effect, and can be used for treating hemiplegia, favoritism and other symptoms caused by cerebrovascular disease and stroke, and the treatment effect is great. The invention also provides a method for preparing the traditional Chinese medicine composition. The method is characterized in that all components are powdered and then uniformly mixed to obtain the traditional Chinese medicines. The preparation method is simple and easy to carry out; the prepared traditional Chinese medicine composition has good effects on treating hypertension, hyperlipidemia and cerebrovascular disease, and causes small side effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to a kind of Chinese medicine composition, preparation method and application thereof.
Background technology
At present, angiopathy is one of disease of serious harm human health, for example, hypertension, hyperlipidemia and cerebrovascular disease, its disability rate and mortality rate are higher.And the Chinese medicine of the treatment angiopathy existing at present just has relaxing muscles and tendons to promote blood circulation, the effect of active, the antithrombotic of promoting blood circulation, anticoagulant, activating blood circulation to dissipate blood stasis.
In Cordyceps militaris (L.) Link., contain the various bioactivators such as Cordyceps polysaccharide and SOD, its medical value is the most remarkable.Wherein, cordycepin is a kind of nucleosides material with antibacterial activity, and core poly A polymerase is had to very strong inhibitory action, in DNA transcript mRNA process, makes mRNA dysmaturity, the growth of anticancer, and have hypoglycemic effect; Cordyceps polysaccharide is a kind of galactomannan of height branch, and it can promote lymphocyte transformation, improves the antibody content of serum IgG and the immunologic function of body, the anticancer ability that presses down cancer of enhancing body self; SOD (superoxide dismutase) can eliminate superoxide radical in body, has defying age, the anticancer effect that presses down cancer; In addition, Cordyceps militaris (L.) Link. also contains abundant selenium (Se), this trace element by acknowledged be the trace element of needed by human, it is the active center of glutathione peroxidase, be connected to the form of selenocystein on the peptide chain of pheron, the normal permeability of the stability of Cell protection film, and the generation of immune stimulatory globulin and antibody, enhancing human body immunity and oxidation resistance; Low intracranial pressure can fall in cordycepic acid significantly, promotes body metabolism, thereby cerebral hemorrhage and cerebral thrombosis disease are eased; Streptokinase has good thrombolytic performance.Although Cordyceps militaris (L.) Link. has very important medical value,, in Chinese medicine composition of the prior art, Cordyceps militaris (L.) Link. is not used for the treatment of to cerebrovascular disease.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition, to solve the above problems.
A kind of Chinese medicine composition is provided in an embodiment of the present invention, has comprised: by weight, Cordyceps militaris (L.) Link. 160-170 part, Pheretima 70-80 part, Flos Carthami 50-55 part, Olibanum 30-40 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
Further, comprising: by weight, Cordyceps militaris (L.) Link. 165-168 part, Pheretima 73-76 part, Flos Carthami 52-55 part, Olibanum 34-38 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
Preferably, the each material in described Chinese medicine composition all adopt 20-30 DEG C dry to water content be below 10%.
Further, the each material in described Chinese medicine composition all adopt 22-26 DEG C dry to water content be below 10%.
Preferably, the dosage form of described Chinese medicine composition is pill or powder.
Preferably, described pill adopts the ethanol of 60-80% to carry out pill as binding agent.
The present invention also provides the preparation method of Chinese medicine composition, comprises the following steps:
Take the each material in described Chinese medicine composition;
Each material is processed into respectively Powdered, mix homogeneously.
The present invention also provides the application of Chinese medicine composition in preparation treatment hyperlipidemia and hypertension and cerebrovascular disease medicament.
The Chinese medicine composition that the embodiment of the present invention provides, by Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae composition, active component in these a few taste medical materials complements each other, there is positive synergism, its side effect of the Chinese medicine composition obtaining is little, can treat cerebrovascular disease, in wind-induced hemiplegia, the symptoms such as hemiplegia, effect good effect, the embodiment of the present invention also provides the method for preparing this Chinese medicine composition, preparation method is simple, the Chinese medicine composition obtaining is in hypertension, hyperlipidemia and cerebrovascular disease have good therapeutic effect, and side effect is little.
Detailed description of the invention
Below by specific embodiment, the present invention is described in further detail.
A kind of Chinese medicine composition is provided in an embodiment of the present invention, has comprised: by weight, Cordyceps militaris (L.) Link. 160-170 part, Pheretima 70-80 part, Flos Carthami 50-55 part, Olibanum 30-40 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
Further, comprising: by weight, Cordyceps militaris (L.) Link. 165-168 part, Pheretima 73-76 part, Flos Carthami 52-55 part, Olibanum 34-38 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae are common Chinese crude drug.Wherein, contain the various bioactivators such as Cordyceps polysaccharide, cordycepic acid, cordycepin and SOD in Cordyceps militaris (L.) Link., its medical value is the most remarkable; Pheretima has heat clearing away arresting convulsion, dredging collateral, relievings asthma, and the effects such as diuresis; Flos Carthami has promoting blood circulation to restore menstrual flow, and eliminating stasis to stop pain contributes to control amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, the skin infection curative effect that swells and ache; Olibanum has that analgesia, antiinflammatory are anticorrosion, the effect of eliminating stasis to stop pain and the eliminating carbuncle of invigorating blood circulation; Scolopendra have dispel the wind, the effect of arresting convulsion, counteracting toxic substances, eliminating stagnation; Radix Rhodiolae has the effects such as invigorating the spleen and benefiting QI, clearing away lung-heat to relieve cough and blood circulation promoting and blood stasis dispelling.The present invention is by these common Chinese crude drug proportionings, its active component of the Chinese medicine composition obtaining interacts, there is the Chinese medicine composition of extraordinary chemiluminescence, its side effect is little, pharmacodynamics test shows, Chinese medicine composition provided by the invention can treat cerebrovascular disease, in the symptom such as wind-induced hemiplegia, hemiplegia, and the disease such as hypertension, hyperlipemia, has good curative effect.
Preferably, the each material in described Chinese medicine composition all adopt 20-30 DEG C dry to water content be below 10%.Adopting the 20-30 DEG C of raw material by Chinese crude drug to dry, is to make the active substance of himself react away in order to prevent excess Temperature, carrys out the active substance in every kind of medical material of reservation as much as possible.Further, the each material in described Chinese medicine composition all adopt 22-26 DEG C dry to water content be below 10%.
Preferably, the dosage form of described Chinese medicine composition is pill or powder.Pill and powder taking convenience, and preparation is simple, and therapeutic effect is good.
Preferably, described pill adopts the ethanol of 60-80% to carry out pill as binding agent.Adopt the ethanol of 60-80% to prepare pill, both can, to the Chinese medicine composition sterilization obtaining, also have various compositions were better fused together, and between composition, interacted and reach better active effect, its composition of the pill obtaining better merges, and has better curative effect.
The present invention also provides the preparation method of Chinese medicine composition, comprises the following steps:
Take the each material in described Chinese medicine composition;
Each material is processed into respectively Powdered, mix homogeneously.
This preparation method is simple, and the whole medicinal ingredients in Chinese medicine composition are mixed, and the Chinese medicine composition obtaining has good therapeutic effect at hypertension, hyperlipidemia and cerebrovascular disease, and side effect is little.
The present invention also provides the application of Chinese medicine composition in preparation treatment hyperlipidemia and hypertension and cerebrovascular disease medicament.
The Chinese medicine composition that the embodiment of the present invention provides, formed by Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae, its side effect of the Chinese medicine composition obtaining is little, the symptoms such as the hemiplegia that can treat that cerebrovascular disease, apoplexy cause, hypertension and hyperlipidemia causes, hemiplegia, trick inconvenience, compared with the Chinese medicine composition of disclosed treatment hypertension, hyperlipemia in prior art and cerebrovascular aspect disease, Chinese medicine composition better efficacy provided by the invention, and side effect is little.
Preparation example 1
By Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae adopt 20 DEG C dry to water content be below 10%, by weight, take 50 parts of 160 parts of Cordyceps militaris (L.) Link., 70 parts of Pheretimas, 50 parts, Flos Carthami, 30 parts of Olibanums, 50 parts of Scolopendras and Radix Rhodiolaes, be processed into respectively Powdered, mix homogeneously, pack by the standard of every bag of 6g, obtain finished product.
Preparation example 2
By Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae adopt 22 DEG C dry to water content be below 10%, by weight, take 55 parts of 165 parts of Cordyceps militaris (L.) Link., 73 parts of Pheretimas, 52 parts, Flos Carthami, 304 parts of Olibanums, 52 parts of Scolopendras and Radix Rhodiolaes, be processed into respectively Powderedly, mix homogeneously, is processed into respectively Powdered, mix homogeneously, add 60% ethanol to make pill, encapsulate and get final product, specification: 6g.
Preparation example 3
By Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae adopt 26 DEG C dry to water content be below 10%, by weight, take 58 parts of 168 parts of Cordyceps militaris (L.) Link., 76 parts of Pheretimas, 55 parts, Flos Carthami, 38 parts of Olibanums, 55 parts of Scolopendras and Radix Rhodiolaes, be processed into respectively Powdered, mix homogeneously, add 70% ethanol to make pill, encapsulate and get final product, specification: 6g.
Preparation example 4
By Cordyceps militaris (L.) Link., Pheretima, Flos Carthami, Olibanum, Scolopendra and Radix Rhodiolae adopt 30 DEG C dry to water content be below 10%, by weight, take 60 parts of 170 parts of Cordyceps militaris (L.) Link., 80 parts of Pheretimas, 55 parts, Flos Carthami, 40 parts of Olibanums, 55 parts of Scolopendras and Radix Rhodiolaes, be processed into respectively Powderedly, mix homogeneously, is processed into respectively Powdered, mix homogeneously, add 80% ethanol to make pill, encapsulate and get final product, specification: 6g.
The Chinese medicine composition that above-mentioned preparation example 1 and preparation example 4 are obtained is respectively got 120 parts of medicines, 120 parts of Chinese medicine compositions (specification of every part is 6g) prepared by the embodiment 1 that is 200910102749.6 with reference to application number, distributing to patient takes, instructions of taking is: three times on the 1st (taking half an hour after meal), each serving with 6g, it it within 20 days, is a course for the treatment of.The patient who takes is the patient of hyperlipidemia, hypertension, cephalemia, cerebral hemorrhage, cerebral thrombosis, cerebral infarction symptom, wherein, patient is divided into Three Estate by ill degree by slight, moderate and severe medically, patient is taken to 1-2 the course for the treatment of of this Chinese medicine composition.
Effective: patient's symptom etc. is clearly better;
Take a turn for the better: the improvement such as patient's symptom;
Invalid: treatment is rear without any effect.
The therapeutic effect of preparation example 1:
The therapeutic effect of preparation example 4:
The therapeutic effect of Chinese medicine composition prepared by the embodiment 1 that is 200910102749.6 with reference to application number:
Above-mentioned comparative test result shows: the patient of contrast test takes the patent No. for 200910102749.6 medicines that provide, the total effective rate obtaining is all lower than 70%, and its total effective rate of Chinese medicine composition provided by the invention is all higher than 87.5%, therefore, Chinese medicine composition drug effect provided by the invention is remarkable, and therapeutic effect is good.
Concrete clinical example is:
Clinical example 1
The * * of Tang, man, 73 years old, be diagnosed as cerebral infarction, babble, half of paralysis, can't take care of oneself, and after taking 1 half course for the treatment of of this medicine, has said clearly, and one side of something is not paralysed, now freedom of movement.
Clinical example 2
Old * *, man, 72 years old, diagnosis cephalemia, the about 5.6-3.8cm of largest face, babble Chu, half of paralysis, is critically ill and goes home under hospital admission secondary, takes after 2 courses for the treatment of of this medicine, speaks clear, and one side of something is not paralysed, now returns to one's perfect health.
Clinical example 3
Liu * *, female, 74 years old, be diagnosed as cerebral thrombosis, babble Chu, half of paralysis, after hospital admission, the corners of the mouth is also crooked, and walking disorder takes after 2 courses for the treatment of of this medicine, and just, freedom of movement, now returns to one's perfect health mouth.
Clinical example 4
Grandson * *, female, 65 years old, suffer from hypertension more than ten years, long-term taking hypertension drug, took after 1 course for the treatment of of this medicine, and blood pressure is normal, substantially does not need to take hypertension drug.
Clinical example 5
Yang Yongfen, female, 40 years old, be diagnosed as cerebral hemorrhage, unbearably, difficulty in walking, took after 2 courses for the treatment of of this medicine in headache, and not bitterly, walking is freely for head.
In sum, Chinese medicine composition provided by the invention, is made up of common Chinese crude drug, preparation method is simple, and production cost is low, through clinical verification, the Chinese medicine composition side effect of preparation is little, and cure rate is high, and hypertension, hyperlipidemia and cerebrovascular disease are had to good therapeutic effect.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a Chinese medicine composition, is characterized in that, comprising: by weight, and Cordyceps militaris (L.) Link. 160-170 part, Pheretima 70-80 part, Flos Carthami 50-55 part, Olibanum 30-40 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
2. Chinese medicine composition according to claim 1, is characterized in that, comprising: by weight, and Cordyceps militaris (L.) Link. 165-168 part, Pheretima 73-76 part, Flos Carthami 52-55 part, Olibanum 34-38 part, Scolopendra 50-55 part and Radix Rhodiolae 50-60 part.
3. Chinese medicine composition according to claim 1 and 2, is characterized in that, the each material in described Chinese medicine composition all adopt 20-30 DEG C dry to water content be below 10%.
4. Chinese medicine composition according to claim 3, is characterized in that, the each material in described Chinese medicine composition all adopt 22-26 DEG C dry to water content be below 10%.
5. Chinese medicine composition according to claim 3, is characterized in that, the dosage form of described Chinese medicine composition is pill or powder.
6. Chinese medicine composition according to claim 5, is characterized in that, described pill adopts the ethanol of 60-80% to carry out pill as binding agent.
7. according to a preparation method for the Chinese medicine composition described in claim 1-6 any one, it is characterized in that, comprise the following steps:
Take the each material in described Chinese medicine composition;
Each material is processed into respectively Powdered, mix homogeneously.
8. the application of the Chinese medicine composition described in claim 1-6 any one in preparation treatment hyperlipidemia and hypertension drug.
9. the application of the Chinese medicine composition described in claim 1-6 any one in preparation treatment cerebrovascular disease medicament.
10. application according to claim 9, is characterized in that, described cerebrovascular disease comprises: cephalemia, cerebral hemorrhage, cerebral thrombosis, cerebral infarction.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104586928A (en) * | 2014-12-29 | 2015-05-06 | 长顺县文会虫草种植有限公司 | Traditional Chinese medicine for treating hypertension and hyperglycemia |
CN105853497A (en) * | 2016-06-20 | 2016-08-17 | 谭烈军 | Preparation method of medicine for treating hypertension, coronary heart disease and coronary artery atherosclerosis |
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CN1110153A (en) * | 1994-04-04 | 1995-10-18 | 赵步长 | Drug composition and medicated cap containing said drug composition for curing cerebrovascular disease and angiocardiopathy |
CN101480471A (en) * | 2009-01-24 | 2009-07-15 | 彭都 | Medicament for treating parkinson's disease and preparation method thereof |
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2014
- 2014-05-15 CN CN201410205687.2A patent/CN103948663B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1110153A (en) * | 1994-04-04 | 1995-10-18 | 赵步长 | Drug composition and medicated cap containing said drug composition for curing cerebrovascular disease and angiocardiopathy |
CN101480471A (en) * | 2009-01-24 | 2009-07-15 | 彭都 | Medicament for treating parkinson's disease and preparation method thereof |
Non-Patent Citations (1)
Title |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104586928A (en) * | 2014-12-29 | 2015-05-06 | 长顺县文会虫草种植有限公司 | Traditional Chinese medicine for treating hypertension and hyperglycemia |
CN104586928B (en) * | 2014-12-29 | 2018-10-23 | 长顺县文会虫草种植有限公司 | Treat the Chinese medicine of hypertension, hyperglycemia |
CN105853497A (en) * | 2016-06-20 | 2016-08-17 | 谭烈军 | Preparation method of medicine for treating hypertension, coronary heart disease and coronary artery atherosclerosis |
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