CN104586928B - Treat the Chinese medicine of hypertension, hyperglycemia - Google Patents
Treat the Chinese medicine of hypertension, hyperglycemia Download PDFInfo
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- CN104586928B CN104586928B CN201410834398.9A CN201410834398A CN104586928B CN 104586928 B CN104586928 B CN 104586928B CN 201410834398 A CN201410834398 A CN 201410834398A CN 104586928 B CN104586928 B CN 104586928B
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Abstract
The invention discloses a kind of Chinese medicines for treating hypertension, hyperglycemia, belong to Chinese medicine；It is intended to provide that a kind of short treating period, quick, cure rate is high, convenient to take, the Chinese medicine for treating hypertension, hyperglycemia.It is mixed after being pulverized by the material medicine of following weight point：Earthworm 45~55, Cordyceps militaris 80~100, Radix Notoginseng 60~75, pueraria lobata 20~30, centipede 10~15, lycopodium calvatum 40~50.Flavour of a drug of the present invention are few, compatibility is simple, convenient to take, and total effective rate is up to 98.3%, obvious effective rate up to 89%；It is a kind of Chinese medicine for treating hypertension, hyperglycemia.
Description
Technical field
The present invention relates to a kind of Chinese medicine more particularly to a kind of Chinese medicines for treating hypertension, hyperglycemia.
Background technology
Hypertension, hyperglycemia, hyperlipidemia simultaneously claim " three high ", actually three kinds of illnesss, also have one individually to highlight or two, three
Combined into patient.Currently, " three high " has become the frequently-occurring disease for the human health that causes harm, common disease, it is that modern society generally acknowledges chronic disease, needs
Lifelong medication.
High blood pressure is the Important cause of disease of a variety of Cardial or cerebral vascular diseases, characterized by arterial pressure increases.High blood pressure meeting
Cause the functional failure of the important liver device such as the heart, brain, kidney；It is the first killer for threatening human health.Currently, western medicine hypertension
Not only side effect and dependence are big, need to take for a long time；And decompression is unstable, cannot dispel old complaint, once it is discontinued, blood pressure meeting
It increases at once.
With the variation and improvement of living standard of living environment and structure, diabetes are in ascendant trend year by year；It has become
For chronic disease most.Diabetic complication is more, and illness is accumulated in the course of time, can cause multiple organ diseases.In industrialized country, diabetes are
As the third-largest death factors, it is only second to heart disease and cancer.Doctor trained in Western medicine diagnoses clinical manifestation with hyperglycemia, high glucose in urine, hyperlipidemia
It is characterized, referred to as diabetes, and its cause of disease is belonged into dyssecretosis, insulin deficit.But why insulin lacks,
How dyssecretosis, thin portion mechanism are then negligent of debate.It is treated multi-purpose filling insulin and takes the changes such as yellow ureide derivative, biguanides
Learn synthetic drug.Although control effect is obvious, cannot eradicate；And cannot be effectively prevented complication growth,
Sprawling and deterioration, side effect harm are larger.In addition, insulin needs to be subcutaneously injected, not only patient is used for a long time and agonizes, but also
Easy to produce tolerance；It is more to take biguanides toxicity；Use more yellow sulfonylurea effect preferable at present,
But often there are the adverse reactions such as abdominal discomfort, loss of appetite, nausea, abdominal pain, diarrhea after using, small number of patients occur jaundice and
Hepar damnification.
How relevant the " three high " disease cause of disease, the interpretation of the cause, onset and process of an illness be, intricate, though there are concern and research in medical circles more, there is no and effectively controls
Treatment method.Thus Chinese patent literature disclose application No. is " 200410073874.6 ", it is entitled " treatment hypertension, hyperlipemia
The Chinese medicine of hyperglycemia ", with application No. is " 201310453742.5 ", the entitled " combinations for the treatment of hypertension
Two patent documents of drug ", that there are flavour of a drug is more for above-mentioned two patent application, compatibility is complicated, takes the defects of trouble.
Invention content
In view of the above defects of the prior art, the present invention is intended to provide a kind of short treating period, quick, cure rate
The Chinese medicine for the treatment of hypertension, hyperglycemia high, convenient to take.
To achieve the goals above, the present invention mixes after being pulverized by the material medicine of following weight point：Earthworm 45~
55, Cordyceps militaris 80~100, Radix Notoginseng 60~75, pueraria lobata 20~30, centipede 10~15, lycopodium calvatum 40~50.
The preferred technical solution of the present invention is：Earthworm 50, Cordyceps militaris 85~95, Radix Notoginseng 65~70, pueraria lobata 25, centipede 13,
Lycopodium calvatum 45.
The present invention best-of-breed technology scheme be：Earthworm 50, Cordyceps militaris 90, Radix Notoginseng 67, pueraria lobata 25, centipede 13, lycopodium calvatum 45.
In the above-mentioned technical solutions, earthworm (Geosaurus) is Annelida Ju Yin sections animal Pheretima aspergillum
Pheretimaas pergilum (E Perrier), popular Pheretimatschiliensis P vulgarisChen, power simulation P
The hirudo leech of guillelmi (Michaelsen) or comb the region between the heart and the diaphragm hair earthworm P pectiniferaMichaelsen.Earthworm ceases with heat-clearing
The effect of wind, arresting convulsion, dredging collateral are relievingd asthma, sharp arteries and veins；There are blood pressure lowering, thrombus dissolving, antiarrhythmic effect, can be used for cerebral thrombus, brain
Infraction, coronary heart disease, apoplexy, joint paralysis, extremity numbness, hemiplegia, the illnesss such as vascular hypertension.
Cordyceps militaris also known as northern Chinese caterpillar Fungus.The multiple biological activities such as cordycepic acid, cordycepin, Cordyceps sinensis polysaccharide and SOD therein
The medical value of substance is the most notable.Cordycepic acid (mannitol) can significantly decrease cranium pressure, promote body metabolism, can make
Cerebral hemorrhage and cerebral thrombosis disease are eased；Cordycepin is a kind of nucleosides material with antibacterial activity, to core polyadenosine
Sour polymerase has very strong inhibiting effect, can inhibit the growth of cancer cell, and plays the role of hypoglycemic；Cordyceps sinensis polysaccharide can promote to drench
Bar cell transformation, improves the antibody content of serum IgG and the immune function of body, can enhance the energy of body itself anticancer suppression cancer
Power；SOD can eliminate superoxide radical in body, have the function of anti-aging, anticancer suppression cancer.The chemical composition of Cordyceps militaris is substantially
It is identical as cordyceps sinensis.Cordyceps sinensis has low serum lipids, promotes the heart, cerebral tissue function, anti-inflammatory, cough-relieving apophlegmatic, calmness, spasmolysis
Etc. multiple functions.Chinese medicine thinks that cordyceps sinensis enters lung kidney two warp, can tonifying lung is cloudy and kidney-replenishing, stop with Gan Pingbao lungs, kidney-nourishing
Blood, resolving sputum overstrain cough, secret lean gas, specially mend gate of vitality and other effects, cure mainly kidney deficiency, consumptive disease hemoptysis, impotence and seminal emission, neurasthenia, robber
The all diseases of sweat spontaneous perspiration, lumbocrural pain, chronic cough and asthma, pulmonary tuberculosis, anaemia；It is the Chinese medicine that can uniquely balance, adjust negative and positive simultaneously.
Radix Notoginseng, sweet slight bitter, temperature；Enter liver, stomach, large intestine channel.With hemostasis, the stasis of blood is dissipated, the effect of detumescence, analgesic therapy, cure mainly spitting of blood,
It spits blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.Modern science proves that Radix Notoginseng can increase coronal dynamic
Arteries and veins blood flow, reducing heart rate reduce myocardial oxygen consumption；And fight the blood pressure raising caused by pituitrin, coronary artery
Contraction has effect.Therefore Radix Notoginseng is widely used in hemostasis, antithrombotic, promotes hematopoiesis, expand blood vessel, blood pressure lowering, resist myocardial ischemia, anti-brain
Ischemic, anti-arrhythmia, antiatherosclerosis, analgesia etc. etc..
Pueraria lobata is the dry root of legume pueraria lobata.Nature and flavor are sweet, pungent, cool；Channel tropism attaches to the lung and stomach meridians.There is expelling pathogenic factors from muscles and skin to bring down a fever, thoroughly
Rash promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie；It is usually used in exterior syndrome fever, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst,
Heat is purged heat dysentery, splenasthenic diarrhea.Pueraria lobata water decoction, alcohol medicinal extract, general flavone and Puerarin have the work of apparent expansion coronary vasodilator
With, can make hat blood flow increase, vascular resistence reduce.Pueraria lobata can be obviously reduced myocardial infarct size, it is considered to be a kind of β-kidney
Upper parathyrine receptor blocker.Pueraria Flavonid and Puerarin energy reducing heart rate reduce heart total peripheral resistance, reduce myocardial oxygen consumption
Amount；Improve myocardium working efficiency.Puerarin can also significantly reduce the generation of myocardial lactate caused by ischemic, improve infarcted myocardium
Metabolism.Effect of the pueraria lobata to blood pressure and peripheral blood vessel：The total Pueraria lobota ketone of pueraria lobata and Puerarin can make plasma renin activity and vasotonia
Element significantly reduces, and blood pressure declines Puerarins and improves significantly to microcirculation disorder, is mainly shown as and increases capilary fortune
The dynamic micro- blood flow of amplitude and raising part；Pueraria Flavonid has the function of apparent expansion of cerebral vascular, improve brain microcirculation and
Peripheral circulation is it is reported that Puerarin can also improve the arrested state of retinal vessel end slightly unit, to improve visual function.Pueraria lobota
Root element can act on adrenolytic blood glucose increasing, have certain hypoglycemic ability.
Centipede, property and flavor of peppery and warm are toxic；Return liver warp.With Inflammation Zhijing, dispersing pathogen accumulation, remove obstruction in channels to relieve pain the effect of.Cure mainly convulsion
Contraction twitch, sore swollen toxin, the diseases such as scrofula tuberculosis, rheumatoid arthritis stubborn, intractable headache.Be clinically used for treatment coronary heart disease, cerebrovascular disease,
Peripheral neuropathy.Centipede, which has, to be adjusted lipid metaboli, improves hemorheology, reduces blood fat；Adjust radical metabolism, enhancing
Myocardium oxidation resistance protects cardiac muscle to be acted on from lipid peroxidation injury；Can also by inhibit vascular endothelial cell growth because
The c-myc gene expressions of sub- VEGF and vascular smooth muscle cells adjust DNA and protein metabolism, inhibit endothelial cell and blood vessel flat
The proliferation of sliding myocyte；By adjusting the balance of NO/ET and the expression of related gene i Juans Nos, ET-lmRNA, blood vessel is protected
Endothelial cell increases coronary blood flow from damage to effectively prevent the formation of atherosclerosis, improves myocardial ischemia.
Result of study shows that centipede has good antiatherosclerosis and prevention myocardial ischemia effect.
Lycopodium calvatum is the alias of the herb of lycopod, is called lycopod, lion grass, riparian greenbrier root and rhizome, big suitable muscle rattan, smallflower magnoliavine root, the tuber of stemona
It stretches muscle, water shakes bamboo, Chinese alpine rush, oxtail and stretches muscle, oxtail section, oxtail volume, water polo flower, great Ye and stretch muscle, wide muscle grass, whiteback greenbrier rhizome, stretch muscle
Spirit etc.；It is bitter in taste, pungent, warm, enter Liver Channel.There is the effect of expelling wind and clearing away cold, dehumidification swelling, relaxing tendons and activating collaterals, cures mainly wind-cold-dampness arthralgia, tendon and vessel
The diseases such as carbuncle, bruises and spasms are ached in contraction.Modern study proves that with cooling, hypotensive activity, by this product flooding agent to experiment
Rabbit has cooling effect.30 mgs/kg of intravenous injection lycopodines can make anesthetized cat, rabbit blood pressure rapid drawdown, toxic dose that can increase
Animal breath amplitude and reduce frequency.
Inventor thinks that hypertension and hyperglycemia substance and people's Diet lifestyle, living environment quality have close pass
System：Although each disease is different for hypertension, hyperglycemia, and Chang Xiangwei companions, reciprocal causation actually refers to its cause of disease, be social progress,
After being well off, people's lives structure and mode do not obtain the adjustment of health, and body loses exercises, eat then must it is sweet its
Taste, wine must then use up that its is emerging, or because of emotional discomfort, or because ferritic wins void, paddy essence is difficult to take the photograph use, and internal organs are difficult to support, in addition exopathogen
Inside invade, the then each portion's void of accumulating in the course of time more very；And cause Chen Jixin to dry up, deep delay blood system, and have heat it is dry in invade detoxification, the stasis of blood then at
Product, then heart be unequal to that it is tired, and kidney water is difficult defeated cloth, more involves spleen, lung, leads to this disease.Therefore it has been recognised by the inventors that though this disease has
Three it is high it is not, it is deep mixed, as long as carrying its guiding principle and taking its neck, the benefits of side's comprehensive improvement can be received.It is treated also must be with promoting blood circulation and removing blood stasis, clear
Heat, which is moisturized, controls its mark, with positive blood source this, dispel the heavy burden of lungs, release that the dirty disease of the heart, liver two is tired, and exterior syndrome can be removed, then there are no
It is concurrent to spread；After with strong kidney and strengthening spleen, tonifying yin with it is solid its, paddy essence is absorbed, and nephrons is able to strong, and primordial essence is sufficient and basic
It is strong, it can use the work(of the comprehensive conditioning of each internal organs naturally, consolidated at all, also the anxiety without recurrence again.
Compared with the prior art, the present invention is by adopting the above-described technical solution, using earthworm, Cordyceps militaris, centipede as main ingredient,
It is aided with Radix Notoginseng, pueraria lobata, lycopodium calvatum；Using the synergistic effect of all medicines, by disperse blood stasis and dredge collateral, improve cycle, to realize elimination body
Interior siltation, adjustment human body balance, make human body functional recovery to good physiological status.Short treating period of the present invention, curative effect be fast, cure rate
It is high, flavour of a drug are few, it is convenient to take, have no toxic side effect, total effective rate is up to 98.3%, and obvious effective rate is up to 89%.
Instructions of taking：Three times per day, it every time 6 grams, takes warm water and swallows within one hour after meal；15 days as one therapeutic course, a course for the treatment of are shown in
Effect, the recovery from illness of three courses for the treatment of；It is better if garlic can be smashed to pieces to soaked take.
It is the model case treated using the present invention below：
Shen so-and-so, man 53 years old suffers from hypertension, hyperglycemia for many years, and long-term dizzy, blood glucose is up to 13.3；Take this
Blood pressure restores normal after one course for the treatment of of invention drug, and blood glucose is reduced to 8.9, and blood glucose is steadily maintained at 7.0 after one and half courses for the treatment of.
Zhang, female 48 years old, suffer from hypertension, hyperglycemia 3 years, long-term dim eyesight, limbs pain；Take drug blood of the present invention
Sugared normal, blood pressure reduces, and limbs pain is eliminated, so far without recurrence.
Chen, man 73 years old, suffer from hypertension burst cerebral hemorrhage and sustain life by oxygen after hospitalize is invalid；Clothes
With this medicine drug Survive the perils of life of the present invention, rehabilitation so far, without recurrence.
Zeng, 68 years old, because of hypertension burst cerebral infarction；It feels dizzy before medication, right side of body is unable to stir any more；Take this medicine sheet
Invention drug three days, right side of body can activity, walk with can descending after a week, rehabilitation so far, without recurrence.
Specific implementation mode
With reference to specific embodiment, the invention will be further described：
Embodiment 1, by 45 grams of earthworm, 100 grams of Cordyceps militaris, 60 grams of Radix Notoginseng, 30 grams of pueraria lobata, 10 grams of centipede, 50 grams of lycopodium calvatum
After pulverizing respectively uniformly.
Embodiment 2, each step is the same as embodiment 1；Wherein, earthworm is 55 grams, Cordyceps militaris is 80 grams, Radix Notoginseng is 75 grams, pueraria lobata
For 20 grams, centipede be 15 grams, lycopodium calvatum is 40 grams.
Embodiment 3, each step is the same as embodiment 1；Wherein, earthworm is 50 grams, Cordyceps militaris is 85 grams, Radix Notoginseng is 70 grams, pueraria lobata
For 25 grams, centipede be 13 grams, lycopodium calvatum is 45 grams.
Embodiment 4, each step is the same as embodiment 1；Wherein, earthworm is 50 grams, Cordyceps militaris is 95 grams, Radix Notoginseng is 65 grams, pueraria lobata
For 25 grams, centipede be 13 grams, lycopodium calvatum is 45 grams.
Embodiment 5, each step is the same as embodiment 1；Wherein, earthworm is 50 grams, Cordyceps militaris is 90 grams, Radix Notoginseng is 67 grams, pueraria lobata
For 25 grams, centipede be 13 grams, lycopodium calvatum is 45 grams.
Claims (3)
1. a kind of Chinese medicine for treating hypertension, hyperglycemia, it is characterised in that mixed after being pulverized by the material medicine of following parts by weight
It forms：Earthworm 45~55, Cordyceps militaris 80~100, Radix Notoginseng 60~75, pueraria lobata 20~30, centipede 10~15, lycopodium calvatum 40~50.
2. the Chinese medicine for the treatment of hypertension according to claim 1, hyperglycemia, it is characterised in that：Earthworm 50, Cordyceps militaris 85~
95, Radix Notoginseng 65~70, pueraria lobata 25, centipede 13, lycopodium calvatum 45.
3. the Chinese medicine for the treatment of hypertension according to claim 1, hyperglycemia, it is characterised in that：Earthworm 50, Cordyceps militaris 90,
Radix Notoginseng 67, pueraria lobata 25, centipede 13, lycopodium calvatum 45.
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| CN1839934A (en) * | 2006-01-14 | 2006-10-04 | 青岛浩普医药研究有限公司 | Chinese traditional medicine and its preparation method and use |
| CN103446384A (en) * | 2013-08-14 | 2013-12-18 | 马靖已 | Traditional Chinese medicine composition for decreasing blood sugar |
| CN103735880A (en) * | 2014-01-25 | 2014-04-23 | 常正 | Traditional Chinese medicine for treating hypertension and hyperglycemia and preparation method thereof |
| CN103948663A (en) * | 2014-05-15 | 2014-07-30 | 沈文才 | Traditional Chinese medicine composition as well as preparation method and application thereof |
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2014
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1839934A (en) * | 2006-01-14 | 2006-10-04 | 青岛浩普医药研究有限公司 | Chinese traditional medicine and its preparation method and use |
| CN103446384A (en) * | 2013-08-14 | 2013-12-18 | 马靖已 | Traditional Chinese medicine composition for decreasing blood sugar |
| CN103735880A (en) * | 2014-01-25 | 2014-04-23 | 常正 | Traditional Chinese medicine for treating hypertension and hyperglycemia and preparation method thereof |
| CN103948663A (en) * | 2014-05-15 | 2014-07-30 | 沈文才 | Traditional Chinese medicine composition as well as preparation method and application thereof |
Non-Patent Citations (2)
| Title |
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| "降压散治疗原发性高血压并高脂血症的临床观察";李绍鸿等;《云南中医学院学报》;19990320;第22卷(第1期);第33-34页 * |
| "高血压合并糖调节受损中医认识及研究进展";李譞等;《中国中西医结合杂志》;20110820;第31卷(第8期);第1146-1148页 * |
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