CN103948645A - Application of freezing technology in drying of phylloporia ribis sporocarp - Google Patents
Application of freezing technology in drying of phylloporia ribis sporocarp Download PDFInfo
- Publication number
- CN103948645A CN103948645A CN201410204769.5A CN201410204769A CN103948645A CN 103948645 A CN103948645 A CN 103948645A CN 201410204769 A CN201410204769 A CN 201410204769A CN 103948645 A CN103948645 A CN 103948645A
- Authority
- CN
- China
- Prior art keywords
- dry
- freezing
- application
- drying
- sporocarp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to application of the freezing technology in drying of phylloporia ribis sporocarp. According to the preparation, fresh phylloporia ribis sporocarp is picked and then treated by freezing, piling for 2 to 5 days and drying; the prepared phylloporia ribis sporocarp has the advantage that the contents of active ingredients, namely, sterols and polysaccharides, are far more than those obtained by the drying method as recorded in Shandong Chinese Materia Medica Standards.
Description
Invention field
The present invention relates to medicine method for making, the particularly application of Refrigeration Technique in Jin Zhi is dry, belongs to medical technical field.
Background technology
Traditional Chinese medicine drying has very long history in China, the Chinese herbal medicine of drying can keep certain medicinal ingredient and be difficult for putrid and deteriorated, the dry important measures as guaranteeing Chinese herbal medicine quality, it is a requisite technical process in Chinese herbal medicine processing, it is in close relations that dry and Chinese medicine are produced, and dry quality will directly affect the quality of product.
Jin Zhi is the dry sporophore of the Hymenochaetaceae of caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb basal part of stem parasitism lobate layer Pseudomonas fungus currant leaf pore fungi [Phylloporia ribis (Schumach.:Fr.) Ryvarden].There is heat-clearing and toxic substances removing, detumescence sore-throat relieving, antiinflammatory, antiviral, suppresses the effect of tumor.Jin Zhi is with a long history Medicinal, is usually used in treating pharyngitis, laryngitis, and tonsillitis, oral inflammation, cancer, diabetes, antibacterial and viral infection and ulcer etc., clinical efficacy is definite.
Jin Zhi records the Chinese crude drug standard > > in < < Shandong Province, and the drying means of gathering is that summer, Qiu Erji gather, and removes impurity, dries in the shade or 60-70 ℃ of oven dry.We study and find to dry in the shade or 60-70 ℃ of oven dry after golden sesame is gathered, and effective ingredient sterols and polysaccharide content are low.
Summary of the invention
The object of this invention is to provide the dry new method of a kind of golden sesame, the golden sesame that the method is dry, the drying means that main effective ingredient sterols and polysaccharide content are recorded far above < < Shandong Province Chinese crude drug standard > >.
The present invention is achieved in that
The application of Refrigeration Technique in Jin Zhi is dry, is characterized in that: get the golden sesame of newly gathering, and freezing, the 2-5 days that banks up is dry.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: freezing is to be refrigerated to freeze.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: freezing is to be refrigerated to-5 ℃ to freeze below.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: dry is that heap postpone is dried or dries or dries.
Of the present inventionly being refrigerated to subzero certain ℃, is to be refrigerated to and to freeze at this subzero certain ℃.
So far completed the present invention, the golden sesame of preparing by drying means of the present invention, the drying means that main effective ingredient sterols and polysaccharide content are recorded far above < < Shandong Province Chinese crude drug standard > >.
Below by test example, further illustrate usefulness of the present invention, test example is intended to further illustrate usefulness of the present invention, but not limitation of the present invention.
By with a collection of golden sesame of newly gathering, process by the following method.
1) dry: shady and cool ventilation place, spread out and dry;
2) dry: 60 ℃ of following oven dry;
3) the freezing oven dry of banking up: be refrigerated to-5 ℃ to freezing, bank up 3 days at dark and damp place, 60 ℃ of following oven dry.
One, the dry golden sesame sterols content comparison of distinct methods
1, instrument and material
Instrument: Agilentl 100 high performance liquid chromatographs, G1315A/B (DAD UV-detector); Medicine: ergosterol reference substance, methanol, ultra-pure water, other reagent are analytical pure.
2, method
Chromatographic condition chromatographic column: Zorbax eclips XDB C8 (150mm * 4.6mm); Mobile phase: methanol; Flow velocity: 1.0 mL/ min; Detect wavelength: 282nm; Column temperature: 30 ℃; Sample size: 20 μ L.Under these conditions, inject sample solution, theoretical cam curve is greater than 10000 in ergosterol.
The preparation of reference substance solution: it is appropriate that precision takes ergosterol reference substance, is mixed with the solution of 0.3mg/mL with methanol, 4 ℃ of cold preservations are standby.
The preparation of need testing solution: get the about 0.5g of each sample powder (crossing sieve No. three), accurately weighed, be placed in tool plug triangular flask, add methanol 40mL, weighed weight, ultrasonic (400W, 40kHz) 1h, place room temperature, weigh, add methanol to former weight, get supernatant and cross 0.45 μ m filter membrane, obtain need testing solution, 4 ℃ of cold preservations are standby.
Sample determination: the accurate need testing solution 20 μ m that draw, injection liquid chromatography, records peak area value, calculates content by dry product.
3, result the results are shown in Table 1.
Table 1 distinct methods is dried golden sesame sterols content (%)
| Drying means | Dry | Dry | The freezing oven dry of banking up |
| Content (%) | 0.11 | 0.12 | 0.42 |
By table 1, found out, Jin Zhi " freezing heap postpone is dry ", sterols content is apparently higher than " drying " and " oven dry ", and known the inventive method has advance.
Two, the dry golden sesame polyoses content comparison of distinct methods
1, instrument and material
Instrument: ultraviolet-uisible spectrophotometer, electronics typing balance, electric-heated thermostatic water bath.
Material: phenol, sulphuric acid, glucose, ethanol.
2. method and result
The preparation of glucose standard solution: precision takes anhydrous glucose 100 mg that are dried to constant weight, puts in 100mL volumetric flask, is diluted with water to scale, shakes up, and obtains.
The preparation of need testing solution: each sample powder (crossing sieve No. three) approximately 0.2 g, accurately weighed, 80% ethanol 100mL refluxes and carries 1h respectively, filters, 80% washing with alcohol for powder (10mL * 3), to remove the interference compositions such as monosaccharide disaccharidase, oligosaccharide.Powder is placed in flask together with filter paper, with 100mL water heating extraction 1 h, filters, and hot wash for mycopowder (10 ml * 3), washing liquid is incorporated to filtrate, and filtrate is moved in 250 volumetric flasks, is diluted to scale, standby.
The selection of maximum absorption wavelength: first use blank solution baseline balance, the accurate 0.6mL glucose standard solution of drawing is placed in 10mL tool plug test tube again, add respectively water and mend to 2.0mL, then each precision adds 5% phenol solution 1mL, shake up, drip rapidly concentrated sulphuric acid 5.0mL, shake up, in 70 ℃ of water-baths, heat 25 min, adopt psychrolusia cooling, from 200-700nm wavelength, carry out full wavelength scanner, trying to achieve maximum absorption wavelength is 490nm.
The mensuration of polysaccharide: the accurate need testing solution 1mL that draws each sample is placed in l0 mL tool plug test tube, adding distil water 1mL, add 5% phenol 1mL, mix, drip rapidly concentrated sulphuric acid 5mL, at once shake up, in 70 ℃ of water-baths, heat 25min, after employing psychrolusia is cooling, in 490nm place colorimetric, survey light absorption value.Press dry product and calculate content.
3, result the results are shown in Table 2.
Table 2 distinct methods is dried golden sesame polyoses content (%)
| Drying means | Dry | Dry | The freezing oven dry of banking up |
| Content (%) | 4.35 | 4.34 | 8.38 |
By table 2, found out, Jin Zhi " heap postpone is dry ", polyoses content is apparently higher than " drying " and " oven dry ", and known the inventive method has advance.
The specific embodiment
The application of Refrigeration Technique in Jin Zhi is dry, is characterized in that: get the golden sesame of newly gathering, and freezing, the 2-5 days that banks up is dry.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: freezing is to be refrigerated to freeze.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: freezing is to be refrigerated to-5 ℃ to freeze below.
The application of Refrigeration Technique of the present invention in Jin Zhi is dry, is characterized in that: freezing rear dry be dry or dry or dry after freezing.
embodiment 1
Get the golden sesame of newly gathering, put in freeze dryer, be refrigerated to-5 ℃ to freezing, at dark and damp place, bank up 2 days, dry.
embodiment 2
Get the golden sesame of newly gathering, put in freeze dryer, be refrigerated to-10 ℃, bank up in the cool 3 days, dry.
embodiment 3
Get the golden sesame of newly gathering, put in freeze dryer, be refrigerated to-20 ℃, indoor, bank up 4 days, dry.
embodiment 4
Get the golden sesame of newly gathering, put in freeze dryer, be refrigerated to-32 ℃ to freezing, outdoor, bank up 3 days, dry.
embodiment 6
Get the golden sesame of newly gathering, put in freeze dryer, be refrigerated to-15 ℃, bank up in the cool 5 days, dry.
Claims (4)
1. the application of Refrigeration Technique in Jin Zhi is dry, is characterized in that: get the golden sesame of newly gathering, and freezing, the 2-5 days that banks up is dry.
2. the application in Jin Zhi is dry according to the Refrigeration Technique of claim 1, is characterized in that: freezing is to be refrigerated to freeze.
3. the application in Jin Zhi is dry according to the Refrigeration Technique of claim 1, is characterized in that: freezing is to be refrigerated to below-5 ℃.
4. the application in Jin Zhi is dry according to the Refrigeration Technique of claim 1, is characterized in that: dry is that heap postpone is dried or dries or dries.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410204769.5A CN103948645A (en) | 2014-05-15 | 2014-05-15 | Application of freezing technology in drying of phylloporia ribis sporocarp |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410204769.5A CN103948645A (en) | 2014-05-15 | 2014-05-15 | Application of freezing technology in drying of phylloporia ribis sporocarp |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103948645A true CN103948645A (en) | 2014-07-30 |
Family
ID=51326087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410204769.5A Pending CN103948645A (en) | 2014-05-15 | 2014-05-15 | Application of freezing technology in drying of phylloporia ribis sporocarp |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103948645A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104154719A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Drying method of Eucommia ulmoides |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904489A (en) * | 2010-03-08 | 2010-12-08 | 廉士文 | Preparation method and application of phylloporia ribis ryvarden series preparations |
| CN103055022A (en) * | 2013-01-10 | 2013-04-24 | 济南康众医药科技开发有限公司 | Method for processing rehmannia and application for rehmannia in preparation for medicine |
-
2014
- 2014-05-15 CN CN201410204769.5A patent/CN103948645A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904489A (en) * | 2010-03-08 | 2010-12-08 | 廉士文 | Preparation method and application of phylloporia ribis ryvarden series preparations |
| CN103055022A (en) * | 2013-01-10 | 2013-04-24 | 济南康众医药科技开发有限公司 | Method for processing rehmannia and application for rehmannia in preparation for medicine |
Non-Patent Citations (2)
| Title |
|---|
| 刘文彬等: "《灵芝育种栽培与加工技术》", 31 May 2000, 上海科学普及出版社 * |
| 刘波: "《中国药用真菌》", 30 April 1974, 山西人民出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104154719A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Drying method of Eucommia ulmoides |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103968647B (en) | The drying means of a kind of gold sesame | |
| CN103027953B (en) | Extractive containing total meroterpenoid of psidium guajave dialdehyde, and preparation method and application thereof | |
| CN103948642A (en) | Application of refrigeration technique in phellinus igniarius drying | |
| CN103948638A (en) | Drying method of medical fungi | |
| CN103948652A (en) | Method for drying lucid ganoderma | |
| CN102119992B (en) | Pharmaceutical preparation prepared from fresh motherwort and fresh aloe and preparation method thereof | |
| CN108272858B (en) | Method for improving quality of selfheal medicinal material | |
| CN102012405B (en) | Detection method for flavonoids compounds in cotton rose general flavone | |
| CN110585383A (en) | Antifungal compound extract, preparation and preparation method thereof | |
| CN104800481A (en) | Preparation method and application of essential oil inclusion compound | |
| CN109010504A (en) | A kind of extracting method of lycium ruthenicum general flavone | |
| Rohmah et al. | Optimization of Extraction of Bioactive Compound from Pegagan Leaves Using Ethanol Solvent With Microwave-Assisted Extraction Method (MAE) | |
| Direkvand-Moghadam et al. | Extraction and measurement of the Quercetin flavonoid of Prosopis farcta in Khouzestan climatic condition | |
| CN104127506B (en) | A kind of production and processing method that can improve desertliving cistanche sheet quality | |
| CN103230434B (en) | Manufacturing process of leonurus | |
| CN103948645A (en) | Application of freezing technology in drying of phylloporia ribis sporocarp | |
| CN103948649A (en) | Method for drying lonicera japonica thumb | |
| CN102688282B (en) | Preparation method of honey-fried liquorice | |
| CN104367622A (en) | Method for extracting alkaloids from herba leonuri | |
| CN102846719B (en) | Method for processing of Green Fructus forsythiae in producing area | |
| CN103565951A (en) | Method for cutting fresh moutan bark decoction pieces | |
| CN102670634A (en) | C-glycosylflavones composition, preparation method and application thereof | |
| CN103948641A (en) | Drying method of Cordyceps | |
| CN103099856A (en) | White paeony root processed product and preparation method thereof | |
| CN103977037A (en) | Phellinus drying method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140730 |