CN103933401B - Wheat tiller extract purposes in preparing oral bacteriostasis medicine - Google Patents
Wheat tiller extract purposes in preparing oral bacteriostasis medicine Download PDFInfo
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- CN103933401B CN103933401B CN201410180432.5A CN201410180432A CN103933401B CN 103933401 B CN103933401 B CN 103933401B CN 201410180432 A CN201410180432 A CN 201410180432A CN 103933401 B CN103933401 B CN 103933401B
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- medicine
- wheat tiller
- wheat
- preparing oral
- ethanol
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Abstract
The present invention relates to wheat tiller extract purposes in preparing oral bacteriostasis medicine.The present invention is by studying wheat tiller extract, it was found that it can have certain bacteria resistance function, and this medicinal material can be furtherd investigate to develop new medicine by this prompting.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to wheat tiller extract and press down in preparation oral cavity
Purposes in bacterium medicine.
Background technology
Human oral cavity is contained within various bacteria, has hundreds of kind more than according to the literature.Wherein cause a disease
Bacterium has again tens kinds more than, bloodthirsty unwrapping wire association bacillus Actinobacillus
Actinomycetemicomtans ATCC43717 is one of modal pathogenic bacteria.It is right to study
The treatment for mouth disease that prevents and treats in pathogenic bacteria has very important realistic meaning.
Summary of the invention
It is an object of the invention to provide wheat tiller extract use in preparing oral bacteriostasis medicine
On the way.
In order to realize the purpose of the present invention, the present invention provides wheat tiller extract to press down in preparation oral cavity
Purposes in bacterium medicine, described antibacterial referring to suppresses bloodthirsty unwrapping wire association bacillus Actinobacillus
actinomycetemicomtans ATCC43717。
Preferably, described medicine can make tablet, dispersible tablet, disintegrated tablet, rapidly dissolving tablet, intestines
Molten, gargle or spray.
Inventor is surprised to find that wheat tiller has certain bacteriostasis, in order to this is better described
Invention, is introduced wheat tiller below:
Wheat tiller
Medicinal material Ji Yuan: for the germination caryopsis of grass naked barley.
Latin plant animal mineral name: Hordeum vulgare L.var.nudum Hook.f.
Nature and flavor are salty, warm；
This medicine described in prior art help digestion and in, staple food amasss turgor；Poor appetite；Vomiting is let out
Rush down, do not find its record at antibacterial aspect through retrieval.
The present invention is by studying wheat tiller extract, it was found that it can have certain and press down
Bacterium function, this medicinal material can be furtherd investigate to develop new medicine by this prompting.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that the reality of the present invention
Executing example is for illustrating rather than limitation of the present invention.Essence pair according to the present invention
The simple modifications that the present invention is carried out broadly falls into the scope of protection of present invention.Unless otherwise saying
Bright, otherwise the percentage in the present invention is percetage by weight.
The preparation of embodiment 1 wheat tiller extract
Take wheat tiller 100 grams, add the 70 volume % ethanol waters of 3 liters, at 50 DEG C
It is heated to reflux 6 hours, drying under reduced pressure, flings to ethanol, then will fling to the aqueous solution after ethanol
It is concentrated into relative density 1.20 at 50 DEG C, places 24 hours at 80 DEG C in an oven, pulverize,
It is weighed as 12.6 grams.
Experimental example bacteriostatic test
Filter paper enzyme classical in this area is used to carry out bacteriostatic test, wherein:
1. material
1.1 for examination bacterial classification
Bloodthirsty unwrapping wire association bacillus Actinobacillus actinomycetemicomtans ATCC
43717 are purchased from Central Plains, Beijing company.
1.2 nutrient solution
Nutrient agar and nutrient broth, purchased from Chen Yu experimental facilities Co., Ltd of BeiJing ZhongKe.
1.3 test method
By bloodthirsty unwrapping wire association bacillus Actinobacillus actinomycetemicomtans ATCC
43717 are inoculated in agar plate nutrient solution plane, uniformly gather during inoculation.Take wheat tiller 100
Gram, add the 70 volume % ethanol waters of 3 liters, be heated to reflux at 50 DEG C 6 hours,
Drying under reduced pressure, flings to ethanol, and the aqueous solution after then flinging to ethanol is concentrated into 500 milliliters.
Tweezer aseptic circular filter paper sheet, the aqueous solution after sprinkling concentration, to complete wetting, is attached to inoculate
In the agar plate nutrient solution plane of bacterium.Agar plate is placed in the incubator of 37 DEG C,
Incubation 4 hours.Measure the diameter of antibacterial ring.Measure and average for 3 times.
1.4 result
Bloodthirsty unwrapping wire association bacillus Actinobacillus actinomycetemicomtans ATCC
The average diameter of the antibacterial ring of 43717 is 15.98mm, shows that wheat tiller extract has excellence
Fungistatic effect.
Claims (1)
1. wheat tiller extract purposes in preparing oral bacteriostasis medicine, it is characterised in that institute
State antibacterial referring to and suppress bloodthirsty unwrapping wire association bacillus Actinobacillus
Actinomycetemicomtans ATCC 43717, described wheat tiller extract is by following side
Method is made: take wheat tiller 100 grams, adds the 70 volume % ethanol waters of 3 liters, at 50 DEG C
Under be heated to reflux 6 hours, drying under reduced pressure, fling to ethanol, then water-soluble by fling to after ethanol
Liquid is concentrated into 500 milliliters.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410180432.5A CN103933401B (en) | 2014-04-30 | 2014-04-30 | Wheat tiller extract purposes in preparing oral bacteriostasis medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410180432.5A CN103933401B (en) | 2014-04-30 | 2014-04-30 | Wheat tiller extract purposes in preparing oral bacteriostasis medicine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103933401A CN103933401A (en) | 2014-07-23 |
| CN103933401B true CN103933401B (en) | 2016-08-24 |
Family
ID=51181456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410180432.5A Expired - Fee Related CN103933401B (en) | 2014-04-30 | 2014-04-30 | Wheat tiller extract purposes in preparing oral bacteriostasis medicine |
Country Status (1)
| Country | Link |
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| CN (1) | CN103933401B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1345599A (en) * | 2000-09-28 | 2002-04-24 | 国家医药管理局上海医药工业研究院 | Oral cavity bacteriostatic composition containing extract of Chinese herb lotus leaf |
| CN102670458A (en) * | 2012-06-06 | 2012-09-19 | 广州中汉口腔用品有限公司 | Oral care solution and preparation process thereof |
-
2014
- 2014-04-30 CN CN201410180432.5A patent/CN103933401B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1345599A (en) * | 2000-09-28 | 2002-04-24 | 国家医药管理局上海医药工业研究院 | Oral cavity bacteriostatic composition containing extract of Chinese herb lotus leaf |
| CN102670458A (en) * | 2012-06-06 | 2012-09-19 | 广州中汉口腔用品有限公司 | Oral care solution and preparation process thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103933401A (en) | 2014-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Guangde Inventor before: Ma Yi |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160420 Address after: No. 44 Jining road 272100 Shandong provincial Stomatological Hospital of the Communist Youth League in Rencheng District of Jining City Applicant after: Zhang Guangde Address before: No. 44 Jining road 272100 Shandong provincial Stomatological Hospital of the Communist Youth League in Rencheng District of Jining City Applicant before: Ma Yi |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160824 Termination date: 20170430 |
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| CF01 | Termination of patent right due to non-payment of annual fee |