CN103919996A - Traditional Chinese medicine for treating arteriosclerosis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating arteriosclerosis, which consists of the following components in parts by weight: 10-20 parts of radix rehmanniae, 10-15 parts of cornelian cherry, 10-15 parts of Polygonatum Canaliculatum, 15-30 parts of Astragalus root, 6-10 parts of red ginseng, 6-10 parts of carrageenin, 9-12 parts of radix asparagi, 10-20 parts of radix ophiopogonis, 15-30 parts of radix salviae miltiorrhizae, 10-15 parts of earthworm, 6-10 parts of leech, 15-30 parts of fried hawthorn, 10-12 parts of notoginseng, 10-15 parts of semen ginkgo, 3-10 parts of vinegar-processed rhubarb, 15-30 parts of dodder, 12-15 parts of medlar, 10-12 parts of radix achyranthis bidentatae, 15-30 parts of kudzu root, 10-15 parts of black small horse, 6-10 parts of tortoise plastron, 10-15 parts of epimedium, 10-12 parts of evening primrose, 12-30 parts of glossy privet fruit, 12-30 parts of Eclipta alba, 10-30 parts of Atractylis ovata, 12-30 parts of Yunnan poria, 12-30 parts of rhizoma alismatis and 6-10 parts of liquorice. According to the traditional Chinese medicine theory, the components are scientifically matched and supplement each other, so that the traditional Chinese medicine has the characteristics of tonifying the kidneys replenishing vitality, promoting blood circulation and nourishing meridian vessels.

Description

A kind ofly treat arteriosclerotic Chinese medicine

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of arteriosclerotic Chinese medicine for the treatment of.

Background technology

Arteriosclerosis is a kind of non-inflammation pathological changes of tremulous pulse, is that ductus arteriosus wall thickens, hardening, follows the string and the narrow and small degeneration of tube chamber and the general name of proliferative lesion, common are atherosclerosis, monckeberg's arteriosclerosis, arteriolosclerosis.Atherosclerosis is type common in arteriosclerosis, is the Etiological of myocardial infarction and cerebral infarction.

Arterioscleroticly generally show as mental and flag, palpation body surface artery is as temporo tremulous pulse, radial artery, and brachial arteryes etc. can be found to broaden, elongated, anfractuosity and hardening.Atherosclerosis of aorta is most of without specific symptom; Coronary atherosclerosis can cause angina pectoris, myocardial infarction and myocardial fibrosis etc.; Cerebral atherosclerosis cerebral ischemia can cause dizzy, headache and the symptom such as faintnesss, cerebral artery thrombosis formation or break and cause cerebrovascular accident when hemorrhage, there is headache, dizzy, vomiting, consciousness is lost suddenly, limbs, paralysis, the performances such as hemianopsia or aphasia, during brain atrophy, cause dementia, spiritedness is abnormal, carries on, and intelligence and hypomnesis are down to symptoms such as personality change completely; It is actually rare clinically that renal artery is atherosis, can cause intractable hypertension; Superior mesenteric atherosclerosis may cause dyspepsia, intestinal hypotension, and the symptoms such as constipation and stomachache, during thrombosis, have tormina, and abdominal distention and heating, when intestinal wall is downright bad, can causes and have blood in stool, the symptoms such as paralytic ileus and shock; Meeting that artery of extremity is atherosis causes that lower limb send out cool, numbness and intermittent claudication.

Atherosclerotic pathological change is mainly involved large-scale elastic-type tremulous pulse (as aorta) and the medium-sized elastic-type tremulous pulse of systemic circulatory system and (with coronary artery and cerebral arteries, is suffered from most, each tremulous pulse of limbs, renal artery and Mesenteric artery take second place, splenic artery also can be got involved), and pulmonary circulation tremulous pulse is seldom got involved; pathological changes distributes and mostly to be several tissues and organ is got involved simultaneously; but sometimes also can concentrate on the tremulous pulse of a certain organ; other tremulous pulsies are normal, occur that the earliest the position of pathological changes is many at vessel branch places such as AoPW and intercostal arteries openings; These position blood pressures are higher, and the impulsive force that tube wall bears blood flow is larger, thereby pathological changes is also more obvious.

Normal arterial wall is by inwall, three layers of formation of middle film and adventitia, and while there is atherosclerosis, there is lipid striped in arterial wall, the variation of fibrous plaque and compound pathological changes three types.Lipid stripe disease becomes early stage pathological changes, be common in adolescence, be confined to endarterium, present the yellow fat point of several mm in sizes or the yellow fat striped that length can reach several centimetres, it is characterized in that the macrophage of inner membrance and minority smooth muscle cell are kitchen range and gather, inside and outside cell, have lipidosis, lipid components is mainly cholesterol and cholesteryl ester, also has phospholipid and triglyceride etc., because lipid striped belongs to smooth or only slightly exceeds the pathological changes of inner membrance, therefore do not make the obstruction of artery of getting involved, do not cause clinical symptoms, its importance is that it likely develops into speckle, fibrous plaque pathological changes has distinctive pathological changes most for carrying out property atherosclerosis, generally be faint yellow, slightly swell and charge in lumen of artery or around the opening part of vessel branch, cause luminal stenosis, this kind of pathological changes is mainly by the connective tissue of neointimal hyperplasia and the smooth muscle cell that contains lipid, macrophage forms, lipid is mainly cholesterol and cholesteryl ester, in lipid deposits, be mixed with cell debris and cholesterol crystal, when speckle volume increases, to film expansion in tube wall, can destroy the muscle fiber of tube wall and elastic fibers and replace the new capillary vessel of connective tissue and hypertrophy, after lipidosis is more, its central basilar part is often because of malnutrition generation degeneration, necrosis and disintegrate, these disintegrate things and lipid are mixed to form medicated porridge sample material, to be atheromatous plaque or medicated porridge sample tumor, it is hemorrhage that complex disease becomes fibrous plaque generation, necrosis, and ulcer, calcification, atheromatous plaque can form so-called medicated porridge sample ulcer because of intimal surface ulceration, after ulceration, medicated porridge sample material enters blood flow becomes embolus, and ulceration place can cause bleeding, and ulcer rough surface easily produces thrombosis.

Primary disease pathological change is made slow progress, and after significantly pathological changes is more common in the prime of life, but significantly symptom is many, in the geratic period, just occurs.

For arteriosclerotic treatment, take Drug therapy as main at present, is secondly operative treatment.Drug therapy mainly be take reduction cholesterolemia, reduction blood triglyceride as main, and often having medicine is simvastatin 10～40mg, every day 1～2 time.Or fibrate ciprofibrate, once a day, each 50～100mg, reduces tissue cholesterol deposition, reduces Adherence of Platelet, increases fibrinolytic activity and lowers fibrinogen concentration, thereby having the effect that suppresses blood clotting.But adjustment hypolipidemic medicine needs long-term taking more.Operative treatment is mainly to narrow or occluding vascular, particularly coronary artery, aorta, and renal artery and artery of extremity are implemented logical again, rebuild or bypass graft, or through chamber blood vessel, change the interventional therapies such as the postoperative placing rack of shape.The current modern medicine of primary disease there is no miracle cure.

Summary of the invention

The object of the invention is to improve the deficiency of prior art and provide a kind of according to tcm theory, science arrange in pairs or groups, complement each other, the arteriosclerotic Chinese medicine for the treatment of of the kidney invigorating benefit unit, the flourish arteries and veins of invigorating blood circulation.

The object of the present invention is achieved like this, a kind ofly treat arteriosclerotic Chinese medicine, by weight portion, to be the Radix Rehmanniae of 10-20 part, the Fructus Corni of 10-15 part, the Rhizoma Polygonati of 10-15 part, the Radix Astragali of 15-30 part, the Radix Ginseng Rubra of 6-10 part, the Colla cornus cervi of 6-10 part, the Radix Asparagi of 9-12 part, the Radix Ophiopogonis of 10-20 part, the Radix Salviae Miltiorrhizae of 15-30 part, the Pheretima of 10-15 part, the Hirudo of 6-10 part, the Fructus Crataegi (parched) of 15-30 part, the Radix Notoginseng of 10-12 part, the Semen Ginkgo core of 10-15 part, the miserable scholar of 3-10 part is yellow, the Semen Cuscutae of 15-30 part, the Fructus Lycii of 12-15 part, the Radix Achyranthis Bidentatae of 10-12 part, the Radix Puerariae of 15-30 part, the Formica fusca of 10-15 part, the Carapax et Plastrum Testudinis of 6-10 part, 10-15 part Herba Epimedii, the moon of 10-12 part is shown in son, the Fructus Ligustri Lucidi of 12-30 part, the Herba Ecliptae of 12-30 part, the Rhizoma Atractylodis Macrocephalae of 10-30 part, the Poria of 12-30 part, the Rhizoma Alismatis of 12-30 part, the Radix Glycyrrhizae of 6-10 part forms.

The pharmacology that the present invention treats arteriosclerosis prescription is that to take the basic theories of Chinese Chinese Traditional Medicine be basis, the kidney invigorating benefit unit, the flourish arteries and veins of invigorating blood circulation, remedying defects and rectifying errors, complements each other.

The Radix Rehmanniae: cold in nature, sweet in the mouth, hardship.GUIXIN, liver, kidney channel.Function clearing away heat and cooling blood, promote the production of body fluid and moisturize.Enter blood system, can clearing heat in YING system the heat of blood system and cooling blood for hemostasis; Radix Rehmanniae quality is moistened the yin nourishing of many liquid energy, and sweet in the mouth is cold in nature can promote the production of body fluid, and has the nourishing YIN to relieve dryness effect of promoting the production of body fluid.

Fructus Corni: slightly warm in nature, sour in the mouth, puckery; Return liver, kidney channel.The effect that has liver and kidney tonifying, essence astringing and desertion stemming.Be usually used in vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst etc.

Rhizoma Polygonati: property is flat, sweet in the mouth; Return lung, spleen, kidney channel.The effect that has nourishing kidney lung moistening, invigorating the spleen and replenishing QI.

The Radix Astragali: slightly warm in nature, sweet in the mouth; Return lung, spleen, liver, kidney channel.There is the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be usually used in treating that the deficiency of vital energy is weak, the metrorrhagia of having blood in stool, carbuncle are difficult bursts etc.Modern pharmacological research thinks that the Radix Astragali has cardiotonic, can make heart contraction amplitude increase, and output increases, more obvious to the effect of poisoning or tired failure heart.Also can directly expand peripheral blood vessel, reduce Peripheral resistance, play the effect of blood pressure lowering.

Radix Ginseng Rubra: warm in nature, sweet in the mouth, micro-hardship; Return spleen, lung, heart channel.Tool strongly invigorating primordial QI, multiple arteries and veins take off admittedly, the merit of nourishing qi to stop.Be used for weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis, heart failure, cardiogenic shock etc.Modern pharmacological research thinks, Radix Ginseng Rubra has excitation to central nervous system, and cardiac muscle and blood vessel are had to direct effect, and amyocardia is also had some improvement.

Colla cornus cervi: warm in nature, sweet in the mouth, salty; Return liver, kidney channel.The effect that has temperature compensation Liver and kidney, beneficial intensive culture blood.Be usually used in that sexual impotence spermatorrhea, the acid of waist knee joint are cold, asthenia is won thin, metrostaxis etc.

Radix Asparagi: cold in nature, sweet in the mouth, micro-hardship; Return liver, lung, kidney channel.The effect that has tranquilizing by nourishing the heart, nourishing kidney lung moistening, loosening bowel to relieve constipation, blood pressure lowering.

Radix Ophiopogonis: cold nature, sweet, micro-hardship; GUIXIN, lung, stomach warp.The effect that has YIN nourishing and the production of body fluid promoting, lung moistening to clear away heart-fire.Be used for that cough due to yin deficiency, interior-heat are quenched one's thirst, vexed insomnia, dryness of the intestine constipation etc.

Radix Salviae Miltiorrhizae: slightly warm in nature, bitter in the mouth; GUIXIN, Liver Channel.The effect that has promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.Modern study thinks that Radix Salviae Miltiorrhizae is obvious to Cardiovascular System, can strengthen myocardial contraction, improve cardiac function; Coronary artery dilating, increases myocardial flow; Expansion peripheral blood vessel, declines blood flow increase, cerebral blood flow; Improve plasmin activity; Extend, clotting time; Anticoagulant, reduces blood viscosity, and antithrombotic forms; The reparation and the regeneration that promote tissue, have inhibitory action to the fibroblast of hyperplasia.Protect the liver, blood fat reducing.

Pheretima: cold in nature, salty in the mouth; Return liver,spleen,kidney warp.The effect that has heat clearing away spasmolytic, suppressing the hyperactive liver to relieve the wind syndrome, dredge the meridian passage, the diuresis of relievining asthma.Cure mainly that calentura is manic, infantile convulsion tic, apoplectic hemiplegia, cough due to lung-heat etc.

Hirudo: property is flat, salty in the mouth, hardship; Return Liver Channel.The effect of have removing blood stasis, removing blood stasis, stimulating the menstrual flow.Be usually used in lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.Modern pharmacological research thinks, Hirudo contains hirudin, can delay and hinder blood coagulation, thereby have blood coagulation resisting function.There is the effects such as treatment apoplexy, hypertension, the clear stasis of blood, amenorrhea, traumatic injury.

Fructus Crataegi (parched): slightly warm in nature, sour in the mouth, sweet.Return spleen, stomach, Liver Channel.The function with promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Be usually used in hyperlipemia, hypertension, coronary heart disease.

Radix Notoginseng: warm in nature, sweet in the mouth, micro-hardship; Return liver, stomach, large intestine channel.There is dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.< < jade is seized medicine solution > > cloud: " Radix Notoginseng and battalion hemostasis, the clots absorbing of promoting blood circulation, clots absorbing blood and hold back fresh blood.”

Semen Ginkgo core: property is flat, sweet in the mouth, hardship, puckery; Effect astringing lung QI for relieving asthma, leukorrhagia stopping are turbid, urine reducing.Modern pharmacological research thinks, Semen Ginkgo core have defying age, antibacterial, improve cardiovascular function, expelling phlegm for arresting cough, antianaphylactic effect.

Miserable scholar is yellow: cold in nature, bitter in the mouth; Return spleen, stomach, large intestine, liver, pericardium channel.The effect that has stasis removing, blood circulation promoting and blood stasis dispelling, promoting the function of the gallbladder to alleviate jaundice.

Semen Cuscutae: property is flat, acrid-sweet flavor; Return through liver, kidney channel.Tool invigorating the liver and kidney, beneficial marrow, the effect of improving eyesight.For the kidney invigorating reducing urination, stop the common medicine of seminal emission.This moral character is soft and moist, flat invigorating the liver and kidney and not dry.

Fructus Lycii: property is flat, sweet in the mouth; Return liver, kidney channel.The effect with replenishing YIN and blood, nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be usually used in treating that Liver and kidney is deficient, the disease such as the soreness of the waist and knees due to asthenia of essence and blood, dizziness, tinnitus, seminal emission, to deficiency of the liver and kindey, essence and blood can not on the disease curative effect such as dim-sighted, the visual deterioration of the eyes that helps due to the order especially good.Modern pharmacological research shows, Fructus Lycii contains the compositions such as carotene, betanin, vitamin A, vitamin B1, vitamin B2, vitamin C and calcium, phosphorus, ferrum, have strengthen leukocyte active, suppress fat in hepatocyte deposition, promote hepatocyte new life's effect, also can blood pressure lowering, blood sugar lowering, blood fat reducing.

Radix Achyranthis Bidentatae: cool in nature, sweet in the mouth, micro-acid; GUIXIN, liver, large intestine channel.The effect that has promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.

Radix Puerariae: cool in nature, sweet in the mouth; Tool expelling pathogenic factors from muscles is delivered the effect of yang invigorating, resolving heat and reducing pathogenic fire toxin expelling.Modern medicine study shows, the isoflavonoid puerarin in Radix Puerariae is effective to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.Myocardial ischemia can effectively be prevented and treated, myocardial infarction, arrhythmia, hypertension, arteriosclerosis etc.Radix Puerariae in Radix Puerariae have obvious hypoglycemic activity, and the contained flavone compound of Radix Puerariae has effect for reducing blood fat, can reduce serum cholesterol, reduces oily three esters, and to treatment hyperglycemia, hyperlipidemia disease, has significant curative effect.And learning memory disorder is had to obvious therapeutical effect.

Formica fusca: property is flat, salty in the mouth, acid; Return liver, kidney channel.The effect that has the kidney invigorating and essence nourishing, dredge the meridian passage, removing toxic substances and promoting subsidence of swelling.Cure mainly suffer from a deficiency of the kidney dizzy tinnitus, insomnia and dreamful sleep, impotence and seminal emission, rheumatic arthralgia, apoplectic hemiplegia, numb hand and foot etc.

Carapax et Plastrum Testudinis:: property is flat, and salty in the mouth is sweet; Return liver, kidney channel.The merit that has nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone.Cure mainly deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, hematemesis and epistaxis, bleeding not during menses, the lumbago atrophic debility of bones etc.

Herba Epimedii: warm in nature, acrid in the mouth, sweet; Return liver, kidney channel.The effect of tool kidney invigorating and YANG supporting, expelling wind and removing dampness, strengthening the tendons and bones.Be used for that impotence and seminal emission, cold caused by deficiency are sterile, frequent micturition incontinence, dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.

The moon is shown in son: property is flat, bitter in the mouth, tepor; Have promoting blood circulation to remove obstruction in the collateral, the suppressing the hyperactive liver that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., detumescence sore effect.Cure mainly apoplectic hemiplegia, stirring-up of pathogenic wind in the interior resulting from deficiency etc.Modern medicine study thinks, month sees that son has blood fat reducing and arteriosclerosis effect, and anti-fatty liver, antiarrhythmic effect.

Fructus Ligustri Lucidi: cool in nature, sweet in the mouth, hardship; Return liver, kidney channel.The merit with nourishing the liver and kidney, black hair improving eyesight.Cure mainly the diseases such as the hepatic and renal YIN deficiency, the head are giddy, Hiccough and deaf, early whitening of hair, soreness of the waist and knees.

Herba Ecliptae: cool in nature, sweet in the mouth, acid; Return kidney, liver, stomach, intestine and small intestine warp.The effect that has cooling blood for hemostasis, the kidney invigorating tonifying YIN.Conventional control the blood disorders such as haematemesis, hemoptysis, and early whitening of beard and hair, leukorrhagia, pudendum pruritus due to damp pathogen.Modern pharmacological research is thought, effective to cardiovascular system diseases coronary heart diseases and angina pectoris.

The Rhizoma Atractylodis Macrocephalae: warm in nature, bitter in the mouth, sweet; Return spleen, stomach warp.Function invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.Be used for that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement etc.

Poria: property is flat, sweet in the mouth, light; GUIXIN, lung, spleen, kidney channel.The function with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study is thought, Poria energy enhancing human body immunity function, and the pachyman composition that it contains, has obvious antitumor and protects the liver dirty effect.

Rhizoma Alismatis: cold in nature, sweet in the mouth, light; Return kidney, urinary bladder channel.Tool promoting diuresis to eliminate damp pathogen, treating stranguria merit expels the heat-evil.Be used for dysuria, the puckery pain of pyretic stranguria, edema distension, have loose bowels, dizziness due to fluid-retention, seminal emission etc.

Radix Glycyrrhizae: property is flat, sweet in the mouth; GUIXIN, spleen, lung, stomach warp.The merit that has eliminating fire and detoxication, relieving spasm to stop pain; Also be good at being in harmonious proportion the property of medicine, separate the poison of hundred medicines.

Prescription pharmacology of the present invention is: the Radix Rehmanniae, Fructus Corni, Rhizoma Polygonati liver and kidney tonifying, nourishing YIN to relieve dryness; The Radix Astragali, Radix Ginseng Rubra, Radix Puerariae invigorating middle warmer yang invigorating QI invigorating are to help blood; Colla cornus cervi temperature compensation Liver and kidney, beneficial intensive culture blood; Radix Asparagi, Radix Ophiopogonis tranquilizing by nourishing the heart, nourishing kidney blood pressure lowering; Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling; Pheretima, Formica fusca, the moon are shown in sub-the kidney invigorating and essence nourishing, dredge the meridian passage; Semen Cuscutae, Fructus Lycii invigorating the liver and kidney, beneficial marrow, replenishing YIN and blood; Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone; Herba Epimedii kidney invigorating and YANG supporting, the flourish arteries and veins of strong muscle; Fructus Ligustri Lucidi, Herba Ecliptae invigorating the liver and kidney, foster Kidney-Yin; Poria, the Rhizoma Atractylodis Macrocephalae, invigorating the spleen and benefiting QI dampness are allayed excitement; Rhizoma Alismatis eliminating dampness by diuresis expels the heat-evil; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.

The present invention is made by the traditional Chinese herbal medicine of China, according to arteriosclerotic pathological characteristic, develops.Arteriosclerotic feature, be exactly that life in healthy energy virtual loss, the expectorant stasis of blood, blood vessels lose and support, show as vexed, uncomfortable in chest pained, the high-fat adiposity of dizziness and tinnitus, insomnia and dreamful sleep, cardiopalmus, flushing stasis, hyperhidrosis night sweat, or blood stickyly increases, vascular plaque, apoplexy cerebral palsy, myocardial infarction and other blood vessels infraction card.Prescription of the present invention is to tackle the problem at its root to the effect of this disease, and tonifying kidney replenishing essence, supplementing QI and nourishing YIN soft pulse, blood circulation promoting and blood stasis dispelling reduce phlegm.Two Zhou Weiyi courses for the treatment of, take effect a general course for the treatment of, and three courses for the treatment of are visible obviously improves, six the course for the treatment of function substantially recover or fully recover.

The present invention is oral medicine, has no side effect, and for many years, patient, without any untoward reaction, follow the tracks of blood test normal, and curative effect does not rebound in medication.

The animal toxicology experiment summary of Chinese medicine of the present invention: object is for observing the acute and long term toxicity effect of rat this prescription for oral administration.Method: having SD rat is study subject, take 4 dosage (40,20,10,5ml/kg), give decoction 540 days for oral administration continuously, observe behind growth promoter, blood, blood biochemical and drug withdrawal 30-180 days of administration rat in the time of 30-240 days, rat body weight, food ration, activity, peripheral hemogram, important organ coefficient are all normal.Biochemical analysis index: each administration group is with blank group contrast, albumin reduces (P > 0.05), total protein and creatinine raise (P > 0.05), alkali phosphatase (ALP) rising (P > 0.05).Conclusions chronic toxicological experiment represents: in this prescription medication process for oral administration, the observation of indices reaction, has no obvious toxic-side effects.Comprehensively think: this prescription is under prescribed dose, and application is safe and reliable.

Prescription of the present invention, no matter multiple patient, two Zhou Mingxian of medication take effect.Clinical symptoms obviously alleviates, and realizes re-set target general 6 courses for the treatment of.

Adopt Chinese medicine clinical practice of the present invention to treat 200 routine patients, treatment group 200 examples, with the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of this prescription, every day potion, decocting 100-150ml, is divided into two parts, sooner or later each portion is taken.Matched group 200 examples, adopt modern clinic conventional therapy, give simvastatin 10～40mg, and twice of every day is oral, and be a course for the treatment of January.No matter total effective rate and obvious effective rate, treatment group is compared with matched group, significant difference.Learn by statistics unity and coherence in writing and process P < 0.05; Total effective rate treatment group is 98%, and matched group is 82%; Obvious effective rate treatment group is 81%, and matched group is 61%.Following table is the therapeutic evaluation after treatment group and treatment of control group:

The dead total effective rate of the effective enabledisable of group number of cases

Treatment group 200 162 34 60 98%

Matched group 200 122 42 38 0 82%

P＜0.05。

The specific embodiment

Below in conjunction with embodiment, the present invention is described in further detail.

Embodiment 1, treat an arteriosclerotic Chinese medicine, by yellow 6 grams of 10 grams, the Radix Rehmanniae, 10 grams of Fructus Corni, 10 grams of Rhizoma Polygonatis, 20 grams of the Radixs Astragali, 6 grams of Radix Ginseng Rubra, 6 grams of Colla cornus cervis, 9 grams of Radix Asparagis, 9 grams of Radix Ophiopogonis, 20 grams of Radix Salviae Miltiorrhizaes, 6 grams of Pheretimas, 6 grams of Hirudos, 30 grams of Fructus Crataegi (parched), 10 grams of Radix Notoginseng, 10 grams of Semen Ginkgo core, miserable scholar, 10 grams of Semen Cuscutae, 10 grams of Fructus Lycii, 6 grams of Radix Achyranthis Bidentataes, 10 grams of Radix Puerariaes, 9 grams of Formica fusca, 6 grams of Carapax et Plastrum Testudiniss, Herba Epimedii 12 gram, months, see that 9 grams of 10 grams of sons, 10 grams of Fructus Ligustri Lucidi, 10 grams of Herba Ecliptaes, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Poria, 9 grams of Rhizoma Alismatis, Radix Glycyrrhizae form.

Embodiment 2, treat an arteriosclerotic Chinese medicine, by yellow 6 grams of 12 grams, the Radix Rehmanniae, 10 grams of Fructus Corni, 10 grams of Rhizoma Polygonatis, 20 grams of the Radixs Astragali, 6 grams of Radix Ginseng Rubra, 6 grams of Colla cornus cervis, 10 grams of Radix Asparagis, 10 grams of Radix Ophiopogonis, 20 grams of Radix Salviae Miltiorrhizaes, 10 grams of Pheretimas, 9 grams of Hirudos, 30 grams of Fructus Crataegi (parched), 10 grams of Radix Notoginseng, 10 grams of Semen Ginkgo core, miserable scholar, 15 grams of Semen Cuscutae, 15 grams of Fructus Lycii, 6 grams of Radix Achyranthis Bidentataes, 12 grams of Radix Puerariaes, 9 grams of Formica fusca, 7 grams of Carapax et Plastrum Testudiniss, Herba Epimedii 12 gram, months, see that 10 grams of 10 grams of sons, 12 grams of Fructus Ligustri Lucidi, 12 grams of Herba Ecliptaes, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 12 grams of Poria, 9 grams of Rhizoma Alismatis, Radix Glycyrrhizae form.

Embodiment 3: a kind ofly treat arteriosclerotic Chinese medicine, by 12 grams, the Radix Rehmanniae, 10 grams of Fructus Corni, 15 grams of Rhizoma Polygonatis, 30 grams of the Radixs Astragali, 6 grams of Radix Ginseng Rubra, 10 grams of Colla cornus cervis, 9 grams of Radix Asparagis, 9 grams of Radix Ophiopogonis, 30 grams of Radix Salviae Miltiorrhizaes, 10 grams of Pheretimas, 6 grams of Hirudos, 30 grams of Fructus Crataegi (parched), 10 grams of Radix Notoginseng, 10 grams of Semen Ginkgo core, yellow 6 grams of miserable scholar, 15 grams of Semen Cuscutae, 15 grams of Fructus Lycii, 6 grams of Radix Achyranthis Bidentataes, 12 grams of Radix Puerariaes, 10 grams of Formica fusca, 8 grams of Carapax et Plastrum Testudiniss, Herba Epimedii 10 gram, months, see that 10 grams of 12 grams of sons, 30 grams of Fructus Ligustri Lucidi, 30 grams of Herba Ecliptaes, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Poria, 10 grams of Rhizoma Alismatis, Radix Glycyrrhizae form.

Embodiment 4: a kind ofly treat arteriosclerotic Chinese medicine, by 12 grams, the Radix Rehmanniae, 12 grams of Fructus Corni, 15 grams of Rhizoma Polygonatis, 20 grams of the Radixs Astragali, 6 grams of Radix Ginseng Rubra, 9 grams of Colla cornus cervis, 12 grams of Radix Asparagis, 12 grams of Radix Ophiopogonis, 15 grams of Radix Salviae Miltiorrhizaes, 9 grams of Pheretimas, 6 grams of Hirudos, 30 grams of Fructus Crataegi (parched), 10 grams of Radix Notoginseng, 10 grams of Semen Ginkgo core, yellow 6 grams of miserable scholar, 12 grams of Semen Cuscutae, 12 grams of Fructus Lycii, 9 grams of Radix Achyranthis Bidentataes, 12 grams of Radix Puerariaes, 10 grams of Formica fusca, 9 grams of Carapax et Plastrum Testudiniss, Herba Epimedii 12 gram, months, see that 6 grams of 12 grams of sons, 20 grams of Fructus Ligustri Lucidi, 20 grams of Herba Ecliptaes, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 12 grams of Poria, 12 grams of Rhizoma Alismatis, Radix Glycyrrhizae form.

Embodiment 5: a kind ofly treat arteriosclerotic Chinese medicine, by 12 grams, the Radix Rehmanniae, 15 grams of Fructus Corni, 12 grams of Rhizoma Polygonatis, 20 grams of the Radixs Astragali, 10 grams of Radix Ginseng Rubra, 6 grams of Colla cornus cervis, 12 grams of Radix Asparagis, 12 grams of Radix Ophiopogonis, 15 grams of Radix Salviae Miltiorrhizaes, 10 grams of Pheretimas, 15 grams of Semen Cuscutae, 15 grams of Fructus Lycii, 10 grams of Radix Achyranthis Bidentataes, 12 grams of Radix Puerariaes, 10 grams of Formica fusca, 10 grams of Carapax et Plastrum Testudiniss, 10 grams of Hirudos, 30 grams of Fructus Crataegi (parched), 10 grams of Radix Notoginseng, 10 grams of Semen Ginkgo core, yellow 6 grams of miserable scholar, 12 grams of Herba Epimedii, the moon is shown in 12 grams of sons, 30 grams of Fructus Ligustri Lucidi, 30 grams of Herba Ecliptaes, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Poria, 10 grams of Rhizoma Alismatis, 10 grams of compositions of Radix Glycyrrhizae.

Embodiment 6, a kind ofly treat arteriosclerotic Chinese medicine, the Radix Rehmanniae by 10 grams, the Fructus Corni of 15 grams, the Rhizoma Polygonati of 10 grams, the Radix Astragali of 30 grams, the Radix Ginseng Rubra of 6 grams, the Colla cornus cervi of 10 grams, the Radix Asparagi of 9 grams, the Radix Ophiopogonis of 20 grams, the Radix Salviae Miltiorrhizae of 15 grams, the Pheretima of 15 grams, the Hirudo of 6 grams, the Fructus Crataegi (parched) of 30 grams, the Radix Notoginseng of 10 grams, the Semen Ginkgo core of 15 grams, the miserable scholar of 3 grams is yellow, the Semen Cuscutae of 30 grams, the Fructus Lycii of 12 grams, the Radix Achyranthis Bidentatae of 12 grams, the Radix Puerariae of 15 grams, the Formica fusca of 15 grams, the Carapax et Plastrum Testudinis of 6 grams, 15 grams of Herba Epimedii, the moon of 10 grams is shown in son, the Fructus Ligustri Lucidi of 30 grams, the Herba Ecliptae of 12 grams, the Rhizoma Atractylodis Macrocephalae of 30 grams, the Poria of 12 grams, the Rhizoma Alismatis of 30 grams, the Radix Glycyrrhizae of 6 grams forms.

Embodiment 7, a kind ofly treat arteriosclerotic Chinese medicine, the Radix Rehmanniae by 20 grams, the Fructus Corni of 10 grams, the Rhizoma Polygonati of 15 grams, the Radix Astragali of 15 grams, the Radix Ginseng Rubra of 10 grams, the Colla cornus cervi of 6 grams, the Radix Asparagi of 12 grams, the Radix Ophiopogonis of 10 grams, the Radix Salviae Miltiorrhizae of 30 grams, the Pheretima of 10 grams, the Hirudo of 10 grams, the Fructus Crataegi (parched) of 15 grams, the Radix Notoginseng of 12 grams, the Semen Ginkgo core of 10 grams, the miserable scholar of 10 grams is yellow, the Semen Cuscutae of 15 grams, the Fructus Lycii of 15 grams, the Radix Achyranthis Bidentatae of 10 grams, the Radix Puerariae of 30 grams, the Formica fusca of 10 grams, the Carapax et Plastrum Testudinis of 10 grams, 10 grams of Herba Epimedii, the moon of 12 grams is shown in son, the Fructus Ligustri Lucidi of 12 grams, the Herba Ecliptae of 30 grams, the Rhizoma Atractylodis Macrocephalae of 10 grams, the Poria of 30 grams, the Rhizoma Alismatis of 12 grams, the Radix Glycyrrhizae of 10 grams forms.

concrete case:

Patient turns round and look at certain, male, 53 years old.Over nearly 2 or three years, often feel dizzy, hypomnesis, on the unexpected obnubilation of successively twice appearance, two, turn over over the past half year, tic of the limbs companion tongue bites, and shows effect about 3～5 minutes, feels extremities aching pain, tired, loss of appetite after outbreak at every turn.Previously without similar outbreak.Check: blood pressure 140/98mmHg.Optical fundus is clear depending on nipple boundary, arteria retina thin, luminous reflectance strengthens, arteriovenous is slightly intersected impression.Nervous system is without other positive signs.Head X-ray anterioposterior and lateral film is normal.Cholesterolemia 6.46mmol/L.Triglyceride 2.85mmol/L, head ultrasonography center line ripple has no displacement, brain CT examination is normal, EEG (electrocardiogram) examination normal, rheoencephalogram inspection prompting blood vessel elasticity degree lowers.Diagnosis: cerebral arteriosclerosis.Use giddy course for the treatment of of this decoction for the treatment obviously to alleviate, treat two the course for the treatment of symptom substantially disappear, follow up a case by regular visits to 2 years not recurrence.

Patient Zhang, male, 50 years old.Break out vertigo more than 2 years, feel suddenly to turn dark before one's eyes during outbreak, self feel float and incline and fall sense, several seconds time, to several minutes, can recover normal after flat crouching.Each outbreak is all being sat the WA outbreak that stands long afterwards or sleep, during outbreak, have nauseating, without vomiting.Previously there is hypotension medical history.After being admitted to hospital, check: blood pressure 90/60mmHg.It is clear that nystagmus is negative, nipple boundary is looked on optical fundus.Arteria retina is thin, reflected light strengthens, arteriovenous is intersected slight impression.Neurologic check other without positive sign.C spine ap & lat sheet shows slight degeneration, cholesterolemia 7.24mmol/L, and brain CT examination is normal, Electrocardioscopy is normal.Diagnosis: cerebral arteriosclerosis.Use two of this decoction for the treatment symptom course for the treatment of substantially to disappear, follow up a case by regular visits to not recurrence in 2 years.

Claims (1)

1. treat arteriosclerotic Chinese medicine for one kind, it is characterized in that by weight portion being the Radix Rehmanniae of 10-20 part, the Fructus Corni of 10-15 part, the Rhizoma Polygonati of 10-15 part, the Radix Astragali of 15-30 part, the Radix Ginseng Rubra of 6-10 part, the Colla cornus cervi of 6-10 part, the Radix Asparagi of 9-12 part, the Radix Ophiopogonis of 10-20 part, the Radix Salviae Miltiorrhizae of 15-30 part, the Pheretima of 10-15 part, the Hirudo of 6-10 part, the Fructus Crataegi (parched) of 15-30 part, the Radix Notoginseng of 10-12 part, the Semen Ginkgo core of 10-15 part, the miserable scholar of 3-10 part is yellow, the Semen Cuscutae of 15-30 part, the Fructus Lycii of 12-15 part, the Radix Achyranthis Bidentatae of 10-12 part, the Radix Puerariae of 15-30 part, the Formica fusca of 10-15 part, the Carapax et Plastrum Testudinis of 6-10 part, 10-15 part Herba Epimedii, the moon of 10-12 part is shown in son, the Fructus Ligustri Lucidi of 12-30 part, the Herba Ecliptae of 12-30 part, the Rhizoma Atractylodis Macrocephalae of 10-30 part, the Poria of 12-30 part, the Rhizoma Alismatis of 12-30 part, the Radix Glycyrrhizae of 6-10 part forms.