CN103893590A - Compound medicament for treating periodontitis - Google Patents
Compound medicament for treating periodontitis Download PDFInfo
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- CN103893590A CN103893590A CN201410106972.9A CN201410106972A CN103893590A CN 103893590 A CN103893590 A CN 103893590A CN 201410106972 A CN201410106972 A CN 201410106972A CN 103893590 A CN103893590 A CN 103893590A
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Abstract
The invention relates to medicinal preparations in the stomatological department, and in particular relates to a compound medicament for treating periodontitis. The compound medicament is prepared from the following components in parts by weight: 20-30 parts of cape jasmine fruit, 15-20 parts of honeysuckle, 8-15 parts of paris polyphylla, 6-12 parts of black nightshade, 5-10 parts of lophatherum gracile, 7-10 parts of fructus forsythiae, 8-12 parts of crotalaria sessiliflora, 5-10 parts of glossy privet fruit, 8-12 parts of Chinese mahonia, 6-10 parts of corydalis tuber and 1-3 parts of rhizoma anemarrhenae. The invention also relates to a preparation method of the compound medicament for treating periodontitis. The compound medicament for treating periodontitis is prepared by selecting eleven natural traditional Chinese medicinal materials, has small toxic and side effects, can be used for treating both symptoms and root causes, has exact curative effects, can be used for completely treating periodontitis, and prevents relapse.
Description
Technical field
The present invention relates to a kind of department of stomatology medicament, particularly a kind of compound medicine for the treatment of periodontitis.
Background technology
Periodontitis is a kind of commonly encountered diseases and frequently-occurring disease, is come to a conclusion as after cancer, cardiovascular and cerebrovascular disease by medical circle, threatens the third-largest killer of human body health, is also " the No.1 killer " of oral health.The clinical symptoms main manifestations of periodontitis is: red swelling of gingiva, hemorrhage, not only hemorrhage in the time brushing teeth, sometimes also can be hemorrhage in the time speaking or sting hard thing, occasionally also can have spontaneous hemorrhage, gingiva color is dark red, and most patients with periodontitis are all accompanied by the symptom of gingival atrophy, as treatment not in time there will be tooth loosening gradually, severe patient causes loss of tooth.Periodontitis is a kind of persistent ailment, under traditional treatment means, is difficult to cure completely, due to the constant recurrence of periodontitis, not only can cause becoming flexible, coming off of tooth, also has close associated with whole body health.Because cementopathia position exists a large amount of pathogenic bacterium, these antibacterials can produce endotoxin may cause the diseases such as arteriosclerosis, acute myocardial infarction, diabetes, and premature infant and low birth weight infant and mother to suffer from periodontitis relevant.At present, the medicament categories for the treatment of periodontitis is a lot, is mainly to play the Western medicine of antiinflammation as main, but most drug can only relief of symptoms, is difficult to eradicate, and Western medicine exists price higher, the shortcoming that side effect is larger.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect that how to overcome prior art, and a kind of compound medicine for the treatment of periodontitis is provided.
For solving the problems of the technologies described above, the compound medicine of this treatment periodontitis by following component according to shown in weight ratio scope prepare, 20～30 parts of Fructus Gardeniaes, 15～20 parts of Flos Loniceraes, 8～15 parts of Rhizoma Paridis, 6～12 parts of Herba Solani Nigris, 5～10 parts of Herba Lophatheris, 7～10 parts of Fructus Forsythiaes, 8～12 parts of Herba Crotalariae sessiliflorae, 5～10 parts of Fructus Ligustri Lucidi, 8～12 parts of Mahonia fortunei (Lindl.)Fedde, 6～10 parts of Rhizoma Corydalis, 1～3 part of the Rhizoma Anemarrhenae.
As optimum ratio scope, described compound medicine by following component according to shown in weight ratio scope prepare, 24～26 parts of Fructus Gardeniaes, 17～19 parts of Flos Loniceraes, 9～11 parts of Rhizoma Paridis, 8～10 parts of Herba Solani Nigris, 7～9 parts of Herba Lophatheris, 8～10 parts of Fructus Forsythiaes, 9～11 parts of Herba Crotalariae sessiliflorae, 7～9 parts of Fructus Ligustri Lucidi, 9～11 parts of Mahonia fortunei (Lindl.)Fedde, 8～10 parts of Rhizoma Corydalis, 1～3 part of the Rhizoma Anemarrhenae.
As optimum ratio, described compound medicine by following component according to shown in weight ratio prepare, 30 parts of Fructus Gardeniaes, 15 parts of Flos Loniceraes, 15 parts of Rhizoma Paridis, 6 parts of Herba Solani Nigris, 10 parts of Herba Lophatheris, 7 parts of Fructus Forsythiaes, 12 parts of Herba Crotalariae sessiliflorae, 5 parts of Fructus Ligustri Lucidi, 12 parts of Mahonia fortunei (Lindl.)Fedde, 6 parts of Rhizoma Corydalis, 3 parts of the Rhizoma Anemarrhenaes.
As optimum ratio, described compound medicine by following component according to shown in weight ratio prepare, 20 parts of Fructus Gardeniaes, 20 parts of Flos Loniceraes, 8 parts of Rhizoma Paridis, 12 parts of Herba Solani Nigris, 5 parts of Herba Lophatheris, 10 parts of Fructus Forsythiaes, 8 parts of Herba Crotalariae sessiliflorae, 10 parts of Fructus Ligustri Lucidi, 8 parts of Mahonia fortunei (Lindl.)Fedde, 10 parts of Rhizoma Corydalis, 1 part of the Rhizoma Anemarrhenae.
As further optimum ratio, described compound medicine by following component according to shown in weight ratio prepare, 26 parts of Fructus Gardeniaes, 17 parts of Flos Loniceraes, 11 parts of Rhizoma Paridis, 8 parts of Herba Solani Nigris, 9 parts of Herba Lophatheris, 8 parts of Fructus Forsythiaes, 11 parts of Herba Crotalariae sessiliflorae, 7 parts of Fructus Ligustri Lucidi, 11 parts of Mahonia fortunei (Lindl.)Fedde, 8 parts of Rhizoma Corydalis, 3 parts of the Rhizoma Anemarrhenaes.
As further optimum ratio, described compound medicine by following component according to shown in weight ratio prepare, 24 parts of Fructus Gardeniaes, 19 parts of Flos Loniceraes, 9 parts of Rhizoma Paridis, 10 parts of Herba Solani Nigris, 7 parts of Herba Lophatheris, 10 parts of Fructus Forsythiaes, 9 parts of Herba Crotalariae sessiliflorae, 9 parts of Fructus Ligustri Lucidi, 9 parts of Mahonia fortunei (Lindl.)Fedde, 10 parts of Rhizoma Corydalis, 1 part of the Rhizoma Anemarrhenae.
As best proportioning, described compound medicine by following component according to shown in weight ratio prepare, 25 parts of Fructus Gardeniaes, 18 parts of Flos Loniceraes, 10 parts of Rhizoma Paridis, 9 parts of Herba Solani Nigris, 8 parts of Herba Lophatheris, 9 parts of Fructus Forsythiaes, 10 parts of Herba Crotalariae sessiliflorae, 8 parts of Fructus Ligustri Lucidi, 10 parts of Mahonia fortunei (Lindl.)Fedde, 9 parts of Rhizoma Corydalis, 2 parts of the Rhizoma Anemarrhenaes.
Pharmacology analysis
Fructus Gardeniae: cold in nature, bitter in the mouth.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold in nature; Return lung, stomach, the heart, large intestine channel; Heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency are treated wind, control disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.
Rhizoma Paridis: hardship, be slightly cold, mild toxicity.Return Liver Channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion.
Herba Solani Nigri: bitter, micro-sweet, cold, mild toxicity.Heat-clearing and toxic substances removing, defying age.
Herba Lophatheri: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Clearing heat and relieving fidgetness, sterilization diuresis.
Fructus Forsythiae: hardship, is slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.
Herba Crotalariae sessiliflorae: light, flat.Nourishing YIN for benefiting the kidney, anti-inflammatory and anticancer.
Fructus Ligustri Lucidi: sweet, bitter, cold.Return liver, kidney channel.Nourishing the liver and kidney, strong tooth, improving eyesight, black hair.
Mahonia fortunei (Lindl.)Fedde: bitter, cold.Return kidney, bladder, large intestine channel.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity ward off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus;
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.。
The Rhizoma Anemarrhenae: bitter, sweet, cold.Return lung, stomach, kidney channel.Clearing away heat-fire, promotes the production of body fluid and moisturizes.
The preparation method of the compound medicine of this treatment periodontitis is: get above-mentioned each component according to above-mentioned arbitrary formula proportion, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medicinal liquid of this treatment periodontitis.
The compound medicine selected ten that the present invention is a kind of treats periodontitis natural traditional Chinese medicine simply, toxic and side effects is little, treating both the principal and secondary aspects of a disease, determined curative effect, can thoroughly cure periodontitis, and is difficult for recurrence.
Detailed description of the invention
Embodiment 1: measure above-mentioned each component according to the formula of Fructus Gardeniae 30g, Flos Lonicerae 15g, Rhizoma Paridis 15g, Herba Solani Nigri 6g, Herba Lophatheri 10g, Fructus Forsythiae 7g, Herba Crotalariae sessiliflorae 12g, Fructus Ligustri Lucidi 5g, Mahonia fortunei (Lindl.)Fedde 12g, Rhizoma Corydalis 6g, Rhizoma Anemarrhenae 3g, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medicinal liquid A of this treatment periodontitis.
Embodiment 2: measure above-mentioned each component according to the formula of Fructus Gardeniae 20g, Flos Lonicerae 20g, Rhizoma Paridis 8g, Herba Solani Nigri 12g, Herba Lophatheri 5g, Fructus Forsythiae 10g, Herba Crotalariae sessiliflorae 8g, Fructus Ligustri Lucidi 10g, Mahonia fortunei (Lindl.)Fedde 8g, Rhizoma Corydalis 10g, Rhizoma Anemarrhenae 1g, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medical liquid B of this treatment periodontitis.
Embodiment 3: measure above-mentioned each component according to the formula of Fructus Gardeniae 26g, Flos Lonicerae 17g, Rhizoma Paridis 11g, Herba Solani Nigri 8g, Herba Lophatheri 9g, Fructus Forsythiae 8g, Herba Crotalariae sessiliflorae 11g, Fructus Ligustri Lucidi 7g, Mahonia fortunei (Lindl.)Fedde 11g, Rhizoma Corydalis 8g, Rhizoma Anemarrhenae 3g, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medicinal liquid C of this treatment periodontitis.
Embodiment 4: measure above-mentioned each component according to the formula of Fructus Gardeniae 24g, Flos Lonicerae 19g, Rhizoma Paridis 9g, Herba Solani Nigri 10g, Herba Lophatheri 7g, Fructus Forsythiae 10g, Herba Crotalariae sessiliflorae 9g, Fructus Ligustri Lucidi 9g, Mahonia fortunei (Lindl.)Fedde 9g, Rhizoma Corydalis 10g, Rhizoma Anemarrhenae 1g, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medicinal liquid D of this treatment periodontitis.
Embodiment 5: measure above-mentioned each component according to the formula of Fructus Gardeniae 25g, Flos Lonicerae 18g, Rhizoma Paridis 10g, Herba Solani Nigri 9g, Herba Lophatheri 8g, Fructus Forsythiae 9g, Herba Crotalariae sessiliflorae 10g, Fructus Ligustri Lucidi 8g, Mahonia fortunei (Lindl.)Fedde 10g, Rhizoma Corydalis 9g, Rhizoma Anemarrhenae 2g, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, 12h boils medicine at 80～90 DEG C, cross leaching filtrate, obtain the compound recipe medicinal liquid E of this treatment periodontitis.
In above embodiment, embodiment 5 is most preferred embodiment.
Clinical data
The compound recipe medicinal liquid E of this treatment periodontitis that above-described embodiment 5 makes, through clinical 400 routine patient's checkings, 90 people's recoveries from illness, 8 people's symptoms are clearly better, and effective percentage 98.0% is below model case:
Model case:
Case 1: grandson, female, 54 years old, suffer from periodontitis more than 2 years, gingiva is often hemorrhage, stings thing unable, and lower front odontoseisis occasionally has dental bed swelling, suppurates, remission after oral administration " antibiotic medicine ".But can not cure prolonged and repeated outbreak always.After take medicine of the present invention after 5 days, dental bed swelling, the transference cure of suppurating, gingival hemorrhage phenomenon disappears substantially, takes medicine after 15 days, above-mentioned symptom disappears completely, stings thing strong.After half a year, follow up a case by regular visits to, the state of an illness does not recur.
Case 2: Lin, man, 42 years old, gingival hemorrhage when brushing teeth two months ago and stinging fruit, by the treatment of local clinic, the state of an illness is without improvement, and further deterioration, and the symptom of taking before medicine of the present invention is: the hyperemia of dental pattern gum, edema, bright and soft, lack flexibility, lower labial teeth place often has pus to overflow more than January.After take medicine of the present invention after 5 days, the congested and edema phenomenon of gingiva disappears substantially, takes medicine after 10 days, the state of an illness is fully recovered.
Case 3: Wang, female, 26 years old.Periodontitis pain 7 days, does not alleviate through taking anti-inflammation analgesic pain, and examine and see the lower-left red swelling of gingiva of grinding one's teeth in sleep, xerostomia happiness drink, dark coloured urine dry stool, tongue limit is slightly red, yellow and thin fur.After take medicine of the present invention after 2 days, red swelling of gingiva phenomenon disappears substantially, take medicine after 5 days, state of an illness recovery from illness.
Above-mentioned embodiment is intended to illustrate the present invention and can be professional and technical personnel in the field's realization or use; it will be apparent for those skilled in the art that above-mentioned embodiment is modified; therefore the present invention includes but be not limited to above-mentioned embodiment; any these claims or description of meeting described; meet and principle disclosed herein and novelty, the method for inventive features, technique, product, within all falling into protection scope of the present invention.
Claims (8)
1. treat the compound medicine of periodontitis for one kind, it is characterized in that: this compound medicine by following component according to shown in weight ratio scope prepare, 20～30 parts of Fructus Gardeniaes, 15～20 parts of Flos Loniceraes, 8～15 parts of Rhizoma Paridis, 6～12 parts of Herba Solani Nigris, 5～10 parts of Herba Lophatheris, 7～10 parts of Fructus Forsythiaes, 8～12 parts of Herba Crotalariae sessiliflorae, 5～10 parts of Fructus Ligustri Lucidi, 8～12 parts of Mahonia fortunei (Lindl.)Fedde, 6～10 parts of Rhizoma Corydalis, 1～3 part of the Rhizoma Anemarrhenae.
2. the compound medicine for the treatment of periodontitis according to claim 1, it is characterized in that: described compound medicine by following component according to shown in weight ratio scope prepare, 24～26 parts of Fructus Gardeniaes, 17～19 parts of Flos Loniceraes, 9～11 parts of Rhizoma Paridis, 8～10 parts of Herba Solani Nigris, 7～9 parts of Herba Lophatheris, 8～10 parts of Fructus Forsythiaes, 9～11 parts of Herba Crotalariae sessiliflorae, 7～9 parts of Fructus Ligustri Lucidi, 9～11 parts of Mahonia fortunei (Lindl.)Fedde, 8～10 parts of Rhizoma Corydalis, 1～3 part of the Rhizoma Anemarrhenae.
3. the compound medicine for the treatment of periodontitis according to claim 1, it is characterized in that: described compound medicine by following component according to shown in weight ratio prepare, 30 parts of Fructus Gardeniaes, 15 parts of Flos Loniceraes, 15 parts of Rhizoma Paridis, 6 parts of Herba Solani Nigris, 10 parts of Herba Lophatheris, 7 parts of Fructus Forsythiaes, 12 parts of Herba Crotalariae sessiliflorae, 5 parts of Fructus Ligustri Lucidi, 12 parts of Mahonia fortunei (Lindl.)Fedde, 6 parts of Rhizoma Corydalis, 3 parts of the Rhizoma Anemarrhenaes.
4. the compound medicine for the treatment of periodontitis according to claim 1, it is characterized in that: described compound medicine by following component according to shown in weight ratio prepare, 20 parts of Fructus Gardeniaes, 20 parts of Flos Loniceraes, 8 parts of Rhizoma Paridis, 12 parts of Herba Solani Nigris, 5 parts of Herba Lophatheris, 10 parts of Fructus Forsythiaes, 8 parts of Herba Crotalariae sessiliflorae, 10 parts of Fructus Ligustri Lucidi, 8 parts of Mahonia fortunei (Lindl.)Fedde, 10 parts of Rhizoma Corydalis, 1 part of the Rhizoma Anemarrhenae.
5. the compound medicine for the treatment of periodontitis according to claim 2, it is characterized in that: described compound medicine by following component according to shown in weight ratio prepare, 26 parts of Fructus Gardeniaes, 17 parts of Flos Loniceraes, 11 parts of Rhizoma Paridis, 8 parts of Herba Solani Nigris, 9 parts of Herba Lophatheris, 8 parts of Fructus Forsythiaes, 11 parts of Herba Crotalariae sessiliflorae, 7 parts of Fructus Ligustri Lucidi, 11 parts of Mahonia fortunei (Lindl.)Fedde, 8 parts of Rhizoma Corydalis, 3 parts of the Rhizoma Anemarrhenaes.
6. the compound medicine for the treatment of periodontitis according to claim 2, it is characterized in that: described compound medicine by following component according to shown in weight ratio prepare, 24 parts of Fructus Gardeniaes, 19 parts of Flos Loniceraes, 9 parts of Rhizoma Paridis, 10 parts of Herba Solani Nigris, 7 parts of Herba Lophatheris, 10 parts of Fructus Forsythiaes, 9 parts of Herba Crotalariae sessiliflorae, 9 parts of Fructus Ligustri Lucidi, 9 parts of Mahonia fortunei (Lindl.)Fedde, 10 parts of Rhizoma Corydalis, 1 part of the Rhizoma Anemarrhenae.
7. the compound medicine for the treatment of periodontitis according to claim 2, it is characterized in that: described compound medicine by following component according to shown in weight ratio prepare, 25 parts of Fructus Gardeniaes, 18 parts of Flos Loniceraes, 10 parts of Rhizoma Paridis, 9 parts of Herba Solani Nigris, 8 parts of Herba Lophatheris, 9 parts of Fructus Forsythiaes, 10 parts of Herba Crotalariae sessiliflorae, 8 parts of Fructus Ligustri Lucidi, 10 parts of Mahonia fortunei (Lindl.)Fedde, 9 parts of Rhizoma Corydalis, 2 parts of the Rhizoma Anemarrhenaes.
8. according to the compound medicine of the arbitrary described treatment periodontitis of claim 1 to 7, it is characterized in that: the preparation method of the compound medicine of described treatment periodontitis is: get above-mentioned each component according to above-mentioned arbitrary formula proportion, after being mixed, each component grinds, cross 200 mesh sieves, with the ratio of mass ratio 1:10 with described in deionized water dissolving, sieve mixture, the 12h that boils medicine at 80～90 DEG C, crosses leaching filtrate, obtains the medicinal liquid of this treatment periodontitis.
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| CN201410106972.9A CN103893590A (en) | 2014-03-21 | 2014-03-21 | Compound medicament for treating periodontitis |
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| CN201410106972.9A CN103893590A (en) | 2014-03-21 | 2014-03-21 | Compound medicament for treating periodontitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106236830A (en) * | 2016-08-30 | 2016-12-21 | 罗嘉辉 | A kind of Chinese medicine treating periodontitis |
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| CN102488849A (en) * | 2011-12-28 | 2012-06-13 | 张君 | Traditional Chinese medicine composition used for treating periodontitis |
| CN102727803A (en) * | 2012-07-20 | 2012-10-17 | 王忠亮 | Medicine for treating periodontitis |
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| CN101439164A (en) * | 2008-12-22 | 2009-05-27 | 徐新民 | Method for preparing Chinese medicine for treating sthenia fire type aphtha |
| CN102488849A (en) * | 2011-12-28 | 2012-06-13 | 张君 | Traditional Chinese medicine composition used for treating periodontitis |
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| CN106236830A (en) * | 2016-08-30 | 2016-12-21 | 罗嘉辉 | A kind of Chinese medicine treating periodontitis |
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