CN103893040A

CN103893040A - Novel medicinal beauty mask

Info

Publication number: CN103893040A
Application number: CN201210579117.0A
Authority: CN
Inventors: 杨雪
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-12-27
Filing date: 2012-12-27
Publication date: 2014-07-02

Abstract

The invention discloses a novel medicinal beauty mask. The medicinal beauty mask comprises an essential component for the mask--zedoary oil and further includes fish collagen, an epidermal growth factor, medicinal water and aqueous non-woven fabric mask paper which can be cooperatively used with zedoary oil for preparation of the medicinal beauty mask. The medicinal beauty mask is used for repairing wounds and removing wrinkles after skin operation and for daily face prevention and skin wrinkles removal.

Description

A kind of newtype drug beauty mask

Technical field

The invention belongs to medical technical field, relate to a kind of newtype drug beauty mask.

Background technology

Just in France, quintessence oil antibiotic property is studied as far back as Chamberland in 1887.Nineteen thirties, Frenchman Rene-MauriceGattefosse has proposed aromatotherapy (Aromatherapic) word, refers to natural essential oil for anti-infective therapy aspect.Now, the ability of quintessence oil inhibition pathogenic bacteria has become irrefutable fact.

Oleum Curcumae is the natural essential oil extracting from zingiberaceous plant Rhizoma Curcumae, RADIX CURCUMAE, Guangxi zedoary, and its main component is multiple sesquiterpenoids, contains 20 Multiple components [1] such as curcumenol, curzerenone, curdione, cupreol.Modern study proves, Oleum Curcumae has multiple pharmacological effect:

Antitumaous effect Oleum Curcumae is verified more reliable antitumaous effect, and its active component is curcumenol, beta-elemene, curdione etc.Oleum Curcumae instrument for cancers is made as it and can strengthens the immunogenicity of oncocyte, thereby brings out or promote the immunological rejection to tumor, outside special beta-elemene decapacitation direct killing tumor cell, still can induce the biological characteristics of its apoptosis and inverse cancer cell.

Antiinflammatory action Rhizoma Curcumae volatile oil can suppress various pathogens growth, and 1% Oleum Curcumae has inhibitory action to animal acetic acid peritonitis, and mice local edema, inflammation and rat granuloma born of the same parents are had to obvious therapeutical effect.

One of antipathogen Oleum Curcumae effective ingredient curcumenol can suppress golden yellow grape coccus, beta hemolytic streptococcus, escherichia coli, Bacillus typhi growth in test tube, infected by influenza A1, A3 type can directly go out Portugal live, RSU is had to direct repression, still can have inhibitory action to rubella, chickenpox virus.

Immune system effect Bian Changwu etc. are to mouse peritoneal injection Oleum Curcumae concentrated solution, and taking normal saline as contrast, result experimental group mouse thymus, spleen weight, lymphocyte absolute value, macrophage phagocytic function, lysozyme activity, serum antibody titer, Ea and Eb garland formation rate, all higher than matched group, show that Oleum Curcumae has immunological enhancement to mice.

In Oleum Curcumae, have the aromatic of various antibacterial, antiviral, antifungal and parasiticide effect, virus is extremely sensitive to the aromatic molecules material of natural essential oil.The most interesting fact that basic research and clinical trial disclose: accepting in natural essential oil therapeutic process, patient's normal cell seems to obtain a kind of resistance to virus infiltration.

Fish collagen is micromolecule small peptide collagen protein, the coarse groove of effectively releiving, desalination microgroove, and skin presents unprecedented compacting.

The active polypeptide that epidermal growth factor (Epidermal growth factor, EGF) is made up of 53 aminoacid, is a kind of important somatomedin of human endocrine, exchanges ganglion cell's growth, propagation and differentiation and plays an important role.The EGF of denier can promote division and the growth of Skin Cell strongly, promotes metabolism, the slowing down skin aging of application on human skin, even makes aging skin again recover elasticity and gloss.In addition, EGF can also irritate some macromole of extracellular (as hyaluronic acid and glycoprotein etc.) thus synthetic and secretion nutrition skin care.

The object of the invention is to provide " a kind of newtype drug beauty mask ", natural extract Oleum Curcumae and fish collagen, epidermal growth factor are organically combined, combine medicinal water and aqueous non-woven fabric face paper, be prepared into a kind of newtype drug beauty mask.

" a kind of newtype drug beauty mask " is that, antiinflammatory antibacterial using having first, the anticancer and natural extract Oleum Curcumae that improves body immunity effect are as main effective ingredient, and have antibacterial and transdermal effect concurrently, successfully replace conventional cosmetics and used chemical transdermal agent, antiseptic, the newtype drug beauty mask being prepared from.Avoid use chemicals easily to produce skin irritation and toxic and side effects; The skin osmosis of Oleum Curcumae, can promote to improve the metabolism of Skin Cell skin microcirculation, thereby make QI and blood unobstructed, makes the ruddy consistent lubricant of whitening skin, being rich in nutrition.

Summary of the invention

The necessary component that " a kind of newtype drug beauty mask " of the present invention comprises is Oleum Curcumae; Also relate in addition fish collagen, hEGF, medicinal water and the aqueous non-woven fabric face paper that can prepare with Oleum Curcumae combination this drug cosmetics facial film.

According to " a kind of newtype drug beauty mask " claimed in claim 1, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.01～0.2 % by weight containing Oleum Curcumae, be preferably 0.05 % by weight.

According to " a kind of newtype drug beauty mask " described in claim 1～2, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.05～0.25 % by weight containing fish collagen; Be preferably 0.15 % by weight.

According to " a kind of newtype drug beauty mask " described in claim 1～3, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.00001～0.002 % by weight containing hEGF, be preferably 0.00005～0.0005 % by weight.

A preparation method for newtype drug beauty mask, it comprises:

A. aqueous non-woven fabric face paper, plastic-aluminum mask packaging bag after folding are respectively charged in plastic bag, after ethylene oxide sterilizing, are placed on cleaning, ventilation ventilates more than 15 days, for subsequent use.

B. press the weighing scale (except face paper and packaging bag weight) of final products, the fish collagen of 0.05～0.25 % by weight is added in approximately 50% medicinal water, be uniformly dissolved and heated and boiled 30 minutes, make solution (1);

C. the weighing scale (except face paper and packaging bag weight) of pressing final products, adds the Oleum Curcumae of 0.01～0.2 % by weight in solution (1) and is uniformly dissolved through the membrane filtration of 0.22 micron, makes solution (2);

D. press the weighing scale (except face paper and packaging bag weight) of final products, by the hEGF of 0.00001～0.002 % by weight through appropriate medicinal water dissolution, the membrane filtration of 0.22 micron adds in solution (2) and is uniformly dissolved again, add medicinal water to recipe quantity, mix, make solution (3);

E. under environment purification, get respectively sterilized aqueous face paper, plastic-aluminum mask packaging bag, in each plastic-aluminum mask packaging bag, add an aqueous face paper; The solution (3) that measures again 25ml, adds in the aluminium plastic packaging bag that face paper is housed, with the sealing of plastic-aluminum heat-sealing machine, makes " a kind of newtype drug beauty mask ".For repairing wound after epidermis operation, dispelling wrinkle; Prevent and dispel wrinkle of skin for daily face.

Advantage of the present invention:

" a kind of newtype drug beauty mask " is that, antiinflammatory antibacterial using having first, the anticancer and natural extract Oleum Curcumae that improves body immunity effect are as main effective ingredient, and have antibacterial and transdermal effect concurrently, successfully replace conventional cosmetics and used chemical transdermal agent, antiseptic, the newtype drug beauty mask being prepared from.Avoid use chemicals easily to produce skin irritation and toxic and side effects.

The skin osmosis of Oleum Curcumae, can promote to improve the metabolism of Skin Cell skin microcirculation, thereby make QI and blood unobstructed, makes the ruddy consistent lubricant of whitening skin, being rich in nutrition.

In addition, auxiliary element somatomedin, under the osmosis of Oleum Curcumae promotes, accelerates to promote propagation, the differentiation of epidermis cell, accelerates the generation of new cell.The quick keratinization of senile cell is come off, rupture, collagen fiber and the elastic fiber of degeneration are repaired, and skin elasticity increases, and wrinkle calms down gradually, disappears;

Fish collagen is micromolecule small peptide collagen protein, the required collagen protein nutrient substance of energy effective supply skin, and the coarse groove of releiving, desalination microgroove, skin presents unprecedented compacting.

Embodiment is used for further illustrating the present invention below, it should be understood that the only non-limiting scope of the present invention for explanation of the following example.

Detailed description of the invention

Embodiment mono-: prepare newtype drug beauty mask

(1) dosage of every each prescription composition of newtype drug beauty mask is as shown in table 1

Table 1

(2) a kind of preparation method of newtype drug beauty mask

A. aqueous non-woven fabric face paper, plastic-aluminum facial film packaging is entered respectively in plastic bag, after ethylene oxide sterilizing, be placed on cleaning, ventilation ventilates more than 15 days, for subsequent use.

B. take respectively fish collagen by the amount of each prescription, add in approximately 50% medicinal water, be uniformly dissolved and heated and boiled 30 minutes, make solution (1);

C. take respectively Oleum Curcumae by the amount of each prescription, add in solution (1) and be uniformly dissolved through the membrane filtration of 0.22 micron, make solution (2);

D. take respectively hEGF by the amount of each prescription, through appropriate medicinal water dissolution, then the membrane filtration of 0.22 micron adds in solution (2) and is uniformly dissolved, and adds medicinal water to prescription amount, mixes, and makes solution (3);

E. under environment purification, get respectively sterilized aqueous non-woven fabric face paper, plastic-aluminum mask packaging bag, in each packaging bag, add a face paper having folded; The solution (3) that measures again 30ml, adds in the aluminium plastic packaging bag that face paper is housed, with the sealing of plastic-aluminum heat-sealing machine, makes " a kind of newtype drug beauty mask ".

Embodiment 2: Pharmacodynamic test

Sample: in the embodiment of the present invention one:

No. 1 facial film of newtype drug beauty mask of preparing with prescription one

No. 4 facial films of newtype drug beauty mask of preparing with prescription four

Positive control: the crease-resistant lifting facial film of epidermal growth factor medical science Korea S Dr.G LUXURY is produced

Instrument: mirror holder type operating magnifier (JX5391039, Suzhou Jiemei Medical Devices Co., Ltd)

Numeral shows slide gauge (GUANGLU)

Method one: choose epidermis post-operative recovery patient 12 people, be divided at random 2 groups, every group of 6 people, swell (cicatrix is the most serious) with micrometering operation cicatrix respectively for one month after surgery, test one group and use No. 1 facial film, contrasting one group uses commercially available Korea S to produce " the crease-resistant lifting facial film of epidermal growth factor medical science ", one of morning every day, late each face mask film, maintenance 30 minutes, after postoperative six months, measure respectively again cicatrix recovery extent, carry out statistical procedures.

Evaluation criterion

To test respectively one group and after one month after surgery, after postoperative June, with its canthus cicatrix protuberance of micrometering, carry out statistical procedures, to evaluate its cicatrix recovery extent with positive control battery of tests person.

Experimental result

Test one group with one group of positive control when the test six month, with micrometering method, cicatrix protuberance in canthus is measured, and is evaluated its cicatrix recovery extent.

Result: test one group of patient canthus cicatrix and obviously alleviate (P < 0.01) before, one group of patient's cicatrix of positive control slightly alleviates (P < 0.05) before, No. 1 facial film and the comparison of positive control facial film, go scar effect there were significant differences justice (P < 0.01);

Table 2 canthus cicatrix protuberance degree

T inspection P < 0.01

Method two: choose women 12 people about 45-55 year, be divided at random 2 groups, every group of 6 people.Before on-test respectively with micrometering canthus wrinkle protuberance degree, test two groups and use No. 4 facial films, contrasting two groups uses commercially available Korea S to produce " the crease-resistant lifting facial film of epidermal growth factor medical science ", one of application at dusk every day, maintenance 30 minutes, recovered after one month, then swelled with micrometering canthus wrinkle respectively, statistics wrinkle protuberance degree changes, and carries out statistical procedures.

Evaluation criterion

To test respectively two groups with two groups of experimenters of positive control before experiment and test after month, use its canthus wrinkle of micrometering protuberance data, carry out statistical procedures, alleviate degree to evaluate its wrinkle.

Experimental result

Test two groups with two groups of positive controls when the test January, with micrometering device, canthus wrinkle protuberance degree is measured, alleviate situation to evaluate its wrinkle.

Result: test two groups of patient's canthus wrinkle and before alleviate (P < 0.01), two groups of patient's wrinkles of positive control are tested front nothing and are obviously changed (P > 0.05), No. 4 samples and positive control comparison, go scar effect to have significant difference (P < 0.01);

Table 3 canthus recovery situation in postoperative March

T inspection P < 0.01.

Claims

1. the necessary component that " a kind of newtype drug beauty mask " of the present invention comprises is Oleum Curcumae; Also relate in addition fish collagen, epidermal growth factor, medicinal water and the aqueous non-woven fabric face paper that can prepare with Oleum Curcumae combination this drug cosmetics facial film.

2. according to " a kind of newtype drug beauty mask " claimed in claim 1, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.01～0.2 % by weight containing Oleum Curcumae, be preferably 0.05 % by weight.

3. according to " a kind of newtype drug beauty mask " described in claim 1～2, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.05～0.25 % by weight containing fish collagen; Be preferably 0.15 % by weight.

4. according to " a kind of newtype drug beauty mask " described in claim 1～3, according to the weighing scale of finished product (except face paper and packaging bag weight), be generally 0.00001～0.002 % by weight containing epidermal growth factor, be preferably 0.00005～0.0005 % by weight.

5. according to " a kind of newtype drug beauty mask " described in claim 1～4, for repairing wound after epidermis operation, dispelling wrinkle; Prevent and dispel wrinkle of skin for daily face.