CN103890586B - 肺癌生物标记及其用途 - Google Patents

肺癌生物标记及其用途 Download PDF

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Publication number
CN103890586B
CN103890586B CN201180074349.4A CN201180074349A CN103890586B CN 103890586 B CN103890586 B CN 103890586B CN 201180074349 A CN201180074349 A CN 201180074349A CN 103890586 B CN103890586 B CN 103890586B
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China
Prior art keywords
biomarker
individual
biomarkers
nsclc
cancer
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CN201180074349.4A
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Chinese (zh)
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CN103890586A (zh
Inventor
M·里尔-米恩
A·A·E·斯图尔特
R·M·奥斯特罗夫
S·A·威廉斯
E·N·布罗迪
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Private Placement Protein Body Operation Co ltd
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Somalogic Inc
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Priority to CN201610457386.8A priority Critical patent/CN106168624B/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201180074349.4A 2011-10-24 2011-10-24 肺癌生物标记及其用途 Active CN103890586B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610457386.8A CN106168624B (zh) 2011-10-24 2011-10-24 肺癌生物标记及其用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/057499 WO2013062515A2 (en) 2011-10-24 2011-10-24 Lung cancer biomarkers and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610457386.8A Division CN106168624B (zh) 2011-10-24 2011-10-24 肺癌生物标记及其用途

Publications (2)

Publication Number Publication Date
CN103890586A CN103890586A (zh) 2014-06-25
CN103890586B true CN103890586B (zh) 2016-06-29

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ID=48168748

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CN201180074349.4A Active CN103890586B (zh) 2011-10-24 2011-10-24 肺癌生物标记及其用途
CN201610457386.8A Active CN106168624B (zh) 2011-10-24 2011-10-24 肺癌生物标记及其用途

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Country Status (15)

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EP (1) EP2771692B1 (https=)
JP (1) JP5986638B2 (https=)
KR (1) KR101921945B1 (https=)
CN (2) CN103890586B (https=)
AU (1) AU2011378427B8 (https=)
BR (1) BR112014006432B8 (https=)
CA (3) CA3064363C (https=)
ES (1) ES2674318T3 (https=)
IL (2) IL231426A (https=)
IN (1) IN2014CN01787A (https=)
MX (1) MX355416B (https=)
NZ (1) NZ621733A (https=)
SG (1) SG11201400375SA (https=)
WO (1) WO2013062515A2 (https=)
ZA (1) ZA201401476B (https=)

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CN112029826B (zh) 2014-07-30 2025-03-14 哈佛学院院长及董事 用于测定核酸的系统和方法
CN104263723B (zh) * 2014-09-15 2017-06-06 南京医科大学 一种与原发性肺癌辅助诊断相关的低频高外显性遗传标志物及其应用
WO2016094330A2 (en) * 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
JP6857185B2 (ja) * 2015-09-11 2021-04-14 アプタマー サイエンス インコーポレイテッドＡｐｔａｍｅｒ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法
EP3372686B1 (en) * 2015-11-05 2020-05-20 BGI Shenzhen Biomarker for detection of lung adenocarcinoma and use thereof
EP4339288A3 (en) * 2016-03-18 2024-06-05 Caris Science, Inc. Oligonucleotide probes and uses thereof
KR101853118B1 (ko) * 2016-09-02 2018-04-30 주식회사 바이오인프라생명과학 피험체의 폐암 진단을 위한 복합 바이오마커군, 이를 이용하는 폐암 진단용 키트, 복합 바이오마커군의 정보를 이용하는 방법 및 이를 수행하는 컴퓨팅 시스템
CN116732143A (zh) * 2016-11-08 2023-09-12 哈佛学院院长及董事 基质印迹和清除
JP7128196B2 (ja) * 2017-03-01 2022-08-30 エフ．ホフマン－ラ ロシュ アーゲー 検体の存在に関する生体サンプルの分類のためのシステムおよび方法
WO2018218150A1 (en) 2017-05-26 2018-11-29 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
CN109116023B (zh) * 2018-06-14 2021-06-04 郑州大学第一附属医院 一种肺癌标志物抗-mmp12自身抗体及其应用
CN109470859A (zh) * 2018-11-04 2019-03-15 华东医院 一种外泌体蛋白作为鉴别肺结节良恶性标志物及其应用
CA3122569A1 (en) 2018-12-13 2020-06-18 President And Fellows Of Harvard College Amplification methods and systems for merfish and other applications
EP3671210A1 (en) * 2018-12-21 2020-06-24 Biosystems International KFT Lung cancer protein epitomic biomarkers
US20220341939A1 (en) * 2019-02-15 2022-10-27 Biodesix, Inc. Predictive test for identification of early stage nsclc stage patients at high risk of recurrence after surgery
CN110473167B (zh) * 2019-07-09 2022-06-17 哈尔滨工程大学 一种基于深度学习的尿沉渣图像识别系统及方法
CN112892619B (zh) * 2019-12-04 2022-07-15 香港城市大学深圳研究院 弧形边缘截面的pdms母模、微流控阀和芯片及其制备
WO2022103843A1 (en) * 2020-11-11 2022-05-19 George Mason Research Foundation, Inc. Laser capture microdissection visualization chemistry
KR102613772B1 (ko) * 2021-02-02 2023-12-14 제노마인(주) 폐암 혈액 바이오마커의 검출 방법 및 키트
WO2025144995A1 (en) * 2023-12-29 2025-07-03 Novelna Inc. Lung cancer detection proteins and methods of use thereof

Citations (3)

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WO2006016697A1 (en) * 2004-08-10 2006-02-16 Oncotherapy Science, Inc. Non-small cell lung cancer-related gene, anln, and its interactions with rhoa
CN101283106A (zh) * 2005-07-27 2008-10-08 肿瘤疗法科学股份有限公司 小细胞肺癌的诊断方法
CN102084253A (zh) * 2008-02-22 2011-06-01 穆比奥产品有限公司 小细胞肺癌生物标记物组

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US6335170B1 (en) * 1999-02-22 2002-01-01 Torben F. Orntoft Gene expression in bladder tumors
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
EP1937837A2 (en) 2005-07-29 2008-07-02 Siemens Healthcare Diagnostics Inc. Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies
US8445198B2 (en) * 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8014957B2 (en) * 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
WO2008046911A2 (en) * 2006-10-20 2008-04-24 Exiqon A/S Novel human micrornas associated with cancer
CA3152591C (en) * 2008-09-09 2023-08-29 Somalogic Operating Co., Inc. Lung cancer biomarkers and uses thereof
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
WO2010056374A2 (en) 2008-11-17 2010-05-20 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
CA2745961A1 (en) * 2008-12-04 2010-06-10 The Regents Of The University Of California Materials and methods for determining diagnosis and prognosis of prostate cancer
US9624547B2 (en) * 2010-02-10 2017-04-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2006016697A1 (en) * 2004-08-10 2006-02-16 Oncotherapy Science, Inc. Non-small cell lung cancer-related gene, anln, and its interactions with rhoa
CN101283106A (zh) * 2005-07-27 2008-10-08 肿瘤疗法科学股份有限公司 小细胞肺癌的诊断方法
CN102084253A (zh) * 2008-02-22 2011-06-01 穆比奥产品有限公司 小细胞肺癌生物标记物组

Also Published As

Publication number Publication date
BR112014006432B8 (pt) 2022-10-25
NZ621733A (en) 2015-05-29
IL231426A0 (en) 2014-04-30
EP2771692A2 (en) 2014-09-03
CA3006793A1 (en) 2013-05-02
IL231426A (en) 2017-06-29
EP2771692A4 (en) 2015-08-26
JP2015501154A (ja) 2015-01-15
IL252163A0 (en) 2017-07-31
CA2847188C (en) 2020-02-18
ES2674318T3 (es) 2018-06-28
ZA201401476B (en) 2016-06-29
IN2014CN01787A (https=) 2015-05-29
BR112014006432A2 (pt) 2017-04-04
WO2013062515A2 (en) 2013-05-02
MX2014004860A (es) 2014-05-27
CA2847188A1 (en) 2013-05-02
AU2011378427B2 (en) 2015-07-16
CN106168624B (zh) 2018-03-13
CN103890586A (zh) 2014-06-25
CA3064363C (en) 2022-05-17
CA3006793C (en) 2020-02-18
WO2013062515A3 (en) 2014-04-17
CA3064363A1 (en) 2013-05-02
AU2011378427A8 (en) 2015-08-27
CN106168624A (zh) 2016-11-30
MX355416B (es) 2018-04-18
EP2771692B1 (en) 2018-04-18
BR112014006432B1 (pt) 2021-04-06
AU2011378427A1 (en) 2013-05-16
KR101921945B1 (ko) 2018-11-26
KR20140082840A (ko) 2014-07-02
SG11201400375SA (en) 2014-04-28
AU2011378427B8 (en) 2015-08-27
JP5986638B2 (ja) 2016-09-06

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Address after: Colorado, USA

Patentee after: Private placement protein body Operation Co.,Ltd.

Address before: Colorado, USA

Patentee before: SOMALOGIC, Inc.