CN103860540A - 奥洛他定在治疗鼻子过敏或发炎状态的制剂制备中的用途 - Google Patents
奥洛他定在治疗鼻子过敏或发炎状态的制剂制备中的用途 Download PDFInfo
- Publication number
- CN103860540A CN103860540A CN201410053676.7A CN201410053676A CN103860540A CN 103860540 A CN103860540 A CN 103860540A CN 201410053676 A CN201410053676 A CN 201410053676A CN 103860540 A CN103860540 A CN 103860540A
- Authority
- CN
- China
- Prior art keywords
- mentioned
- preparation
- spraying
- olopatadine
- purposes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract 23
- JBIMVDZLSHOPLA-LSCVHKIXSA-N olopatadine Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 JBIMVDZLSHOPLA-LSCVHKIXSA-N 0.000 title claims abstract 14
- 229960004114 olopatadine Drugs 0.000 title claims abstract 14
- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract 5
- 208000026935 allergic disease Diseases 0.000 title claims abstract 5
- 230000007815 allergy Effects 0.000 title claims abstract 5
- 206010039083 rhinitis Diseases 0.000 title abstract 2
- 239000007921 spray Substances 0.000 claims abstract 10
- 238000005507 spraying Methods 0.000 claims 20
- 239000000443 aerosol Substances 0.000 claims 3
- 230000002757 inflammatory effect Effects 0.000 claims 3
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
- A61L9/04—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
- A61M11/007—Syringe-type or piston-type sprayers or atomisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63088604P | 2004-11-24 | 2004-11-24 | |
| US60/630,886 | 2004-11-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800402263A Division CN101065122A (zh) | 2004-11-24 | 2005-10-31 | 输送鼻孔喷雾剂的方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103860540A true CN103860540A (zh) | 2014-06-18 |
Family
ID=36498400
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800402263A Pending CN101065122A (zh) | 2004-11-24 | 2005-10-31 | 输送鼻孔喷雾剂的方法 |
| CN201410053676.7A Pending CN103860540A (zh) | 2004-11-24 | 2005-10-31 | 奥洛他定在治疗鼻子过敏或发炎状态的制剂制备中的用途 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800402263A Pending CN101065122A (zh) | 2004-11-24 | 2005-10-31 | 输送鼻孔喷雾剂的方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20060110328A1 (enExample) |
| EP (1) | EP1814538B1 (enExample) |
| JP (1) | JP5068172B2 (enExample) |
| KR (1) | KR101158603B1 (enExample) |
| CN (2) | CN101065122A (enExample) |
| AT (1) | ATE443516T1 (enExample) |
| AU (1) | AU2005309951B2 (enExample) |
| BR (1) | BRPI0518283A2 (enExample) |
| CA (1) | CA2586553C (enExample) |
| CY (1) | CY1110528T1 (enExample) |
| DE (1) | DE602005016833D1 (enExample) |
| DK (1) | DK1814538T3 (enExample) |
| ES (1) | ES2331619T3 (enExample) |
| MX (1) | MX2007005845A (enExample) |
| PL (1) | PL1814538T3 (enExample) |
| PT (1) | PT1814538E (enExample) |
| SI (1) | SI1814538T1 (enExample) |
| WO (1) | WO2006057769A2 (enExample) |
| ZA (1) | ZA200704139B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104063850B (zh) * | 2014-06-24 | 2017-02-01 | 广东互维科技有限公司 | 红眼修复方法 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6788460B2 (en) | 1998-04-15 | 2004-09-07 | Duke University | Projection screen apparatus |
| US6829087B2 (en) | 1998-04-15 | 2004-12-07 | Bright View Technologies, Inc. | Micro-lens array based light transmitting screen with tunable gain |
| US6816306B2 (en) | 1998-04-15 | 2004-11-09 | Bright View Technologies Inc. | Micro-lens array based light transmitting screen with high resolution and low imaging artifacts |
| US7977376B2 (en) * | 2001-06-27 | 2011-07-12 | Novartis Ag | Olopatadine formulations for topical nasal administration |
| BRPI0721255B8 (pt) | 2007-02-07 | 2021-05-25 | Alcon Pharmaceuticals Ltd | composições de olopatadina para administração nasal tópica |
| WO2011008923A2 (en) * | 2009-07-17 | 2011-01-20 | Alcon Research, Ltd. | Olopatadine nasal spray regimen for children |
| WO2011027322A1 (en) | 2009-09-03 | 2011-03-10 | Ranbaxy Laboratories Limited | Extended release dosage form containing olopatadine for oral administration |
| GB2485604A (en) * | 2010-11-22 | 2012-05-23 | Martin Chard | Device for marking a surface |
| US9937189B2 (en) * | 2013-09-13 | 2018-04-10 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| MY191380A (en) * | 2013-09-13 | 2022-06-21 | Glenmark Specialty Sa | Stabilized fixed dose drug composition having mometasone and olopatadine |
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| US10548907B2 (en) | 2013-10-04 | 2020-02-04 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10653661B2 (en) | 2013-10-04 | 2020-05-19 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10016443B2 (en) | 2013-10-04 | 2018-07-10 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| HK1215674A1 (zh) | 2013-10-04 | 2016-09-09 | Glenmark Pharmaceuticals Limited | 结合使用莫米松和奥洛他定治疗过敏性鼻炎 |
| US11679210B2 (en) | 2014-10-03 | 2023-06-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| CN107569454B (zh) * | 2017-09-29 | 2018-05-04 | 深圳大佛药业股份有限公司 | 一种盐酸奥洛他定鼻喷雾剂及其制备方法 |
| US12303635B2 (en) | 2018-04-16 | 2025-05-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| US11890409B1 (en) * | 2019-11-19 | 2024-02-06 | Saeed Rezakhany | Methods of curing early stages of, and preventing, upper respiratory infections and applicators therefor |
| USD969992S1 (en) * | 2020-12-23 | 2022-11-15 | Aptar France Sas | Device for nasal spray |
| JP2025506999A (ja) * | 2022-03-02 | 2025-03-13 | ヴィジャイ ドュッガル | 粘膜の保護および治療のための過酸化水素ベースの治療用スプレー仮出願への相互参照 本出願は、2022年3月に出願された米国仮出願第633109710号の利益を受けるものである。 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE555319A (enExample) * | 1956-03-21 | 1900-01-01 | ||
| GB8520662D0 (en) * | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) * | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| IE61488B1 (en) * | 1987-08-13 | 1994-11-02 | Glaxo Group Ltd | Indole derivatives |
| JPH0323237U (enExample) * | 1989-07-19 | 1991-03-11 | ||
| US5641805A (en) * | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| US5976573A (en) * | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
| FR2803612B1 (fr) * | 2000-01-12 | 2002-12-06 | Michel Jean Louis Mar Doustaly | Point d'eau sanitaire adaptable a une cuvette de wc |
| GB0014892D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| IT1317998B1 (it) * | 2000-06-26 | 2003-07-21 | Medical Internat Licensing N V | Valvola erogatrice per spray nasale. |
| TWI231759B (en) * | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
| WO2003024484A1 (fr) * | 2001-09-14 | 2003-03-27 | Ono Pharmaceutical Co., Ltd. | Medicaments pour traiter le prurit |
| WO2004043470A1 (en) * | 2002-11-12 | 2004-05-27 | Alcon, Inc. | The use of an anti-allergy agent and a steroid to treat allergic rhinitis |
| WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
-
2005
- 2005-10-31 US US11/263,240 patent/US20060110328A1/en not_active Abandoned
- 2005-10-31 JP JP2007543080A patent/JP5068172B2/ja not_active Expired - Lifetime
- 2005-10-31 DK DK05820776T patent/DK1814538T3/da active
- 2005-10-31 PT PT05820776T patent/PT1814538E/pt unknown
- 2005-10-31 WO PCT/US2005/039268 patent/WO2006057769A2/en not_active Ceased
- 2005-10-31 CA CA2586553A patent/CA2586553C/en not_active Expired - Lifetime
- 2005-10-31 CN CNA2005800402263A patent/CN101065122A/zh active Pending
- 2005-10-31 AU AU2005309951A patent/AU2005309951B2/en not_active Expired
- 2005-10-31 EP EP05820776A patent/EP1814538B1/en not_active Expired - Lifetime
- 2005-10-31 SI SI200530855T patent/SI1814538T1/sl unknown
- 2005-10-31 DE DE602005016833T patent/DE602005016833D1/de not_active Expired - Lifetime
- 2005-10-31 MX MX2007005845A patent/MX2007005845A/es active IP Right Grant
- 2005-10-31 KR KR1020077014446A patent/KR101158603B1/ko not_active Expired - Lifetime
- 2005-10-31 BR BRPI0518283-2A patent/BRPI0518283A2/pt not_active Application Discontinuation
- 2005-10-31 CN CN201410053676.7A patent/CN103860540A/zh active Pending
- 2005-10-31 ES ES05820776T patent/ES2331619T3/es not_active Expired - Lifetime
- 2005-10-31 PL PL05820776T patent/PL1814538T3/pl unknown
- 2005-10-31 AT AT05820776T patent/ATE443516T1/de active
- 2005-10-31 ZA ZA200704139A patent/ZA200704139B/xx unknown
-
2009
- 2009-11-03 CY CY20091101136T patent/CY1110528T1/el unknown
-
2013
- 2013-11-14 US US14/079,730 patent/US20140227326A1/en not_active Abandoned
-
2017
- 2017-03-03 US US15/448,834 patent/US20170172974A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104063850B (zh) * | 2014-06-24 | 2017-02-01 | 广东互维科技有限公司 | 红眼修复方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5068172B2 (ja) | 2012-11-07 |
| BRPI0518283A2 (pt) | 2008-11-11 |
| KR101158603B1 (ko) | 2012-07-09 |
| US20060110328A1 (en) | 2006-05-25 |
| CA2586553A1 (en) | 2006-06-01 |
| WO2006057769A2 (en) | 2006-06-01 |
| US20140227326A1 (en) | 2014-08-14 |
| SI1814538T1 (sl) | 2010-01-29 |
| AU2005309951A1 (en) | 2006-06-01 |
| DK1814538T3 (da) | 2009-11-02 |
| MX2007005845A (es) | 2007-07-04 |
| DE602005016833D1 (de) | 2009-11-05 |
| KR20070086638A (ko) | 2007-08-27 |
| JP2008521488A (ja) | 2008-06-26 |
| CN101065122A (zh) | 2007-10-31 |
| CY1110528T1 (el) | 2015-04-29 |
| US20170172974A1 (en) | 2017-06-22 |
| PT1814538E (pt) | 2009-11-10 |
| ZA200704139B (en) | 2008-10-29 |
| PL1814538T3 (pl) | 2010-02-26 |
| WO2006057769A3 (en) | 2006-08-31 |
| CA2586553C (en) | 2015-02-10 |
| EP1814538A2 (en) | 2007-08-08 |
| EP1814538B1 (en) | 2009-09-23 |
| EP1814538A4 (en) | 2007-11-07 |
| AU2005309951B2 (en) | 2011-07-07 |
| ES2331619T3 (es) | 2010-01-11 |
| ATE443516T1 (de) | 2009-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140618 |
|
| RJ01 | Rejection of invention patent application after publication |