CN103857790B - 从aav制剂中去除污染病毒 - Google Patents

从aav制剂中去除污染病毒 Download PDF

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Publication number
CN103857790B
CN103857790B CN201280049899.5A CN201280049899A CN103857790B CN 103857790 B CN103857790 B CN 103857790B CN 201280049899 A CN201280049899 A CN 201280049899A CN 103857790 B CN103857790 B CN 103857790B
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sample
virus
baculovirus
aav
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CN103857790A (zh
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W·T·J·M·C·赫尔门斯
J·P·史密斯
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Uniqure IP BV
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    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
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    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
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    • B01D2311/2623—Ion-Exchange
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    • B01D—SEPARATION
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CN201280049899.5A 2011-09-08 2012-09-07 从aav制剂中去除污染病毒 Expired - Fee Related CN103857790B (zh)

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US201161532176P 2011-09-08 2011-09-08
US61/532,176 2011-09-08
EP11180594.1 2011-09-08
EP11180594 2011-09-08
PCT/NL2012/050619 WO2013036118A1 (en) 2011-09-08 2012-09-07 Removal of contaminating viruses from aav preparations

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EP (3) EP3425044A1 (enExample)
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