CN103846113B - Full-automatic shifting liquid instrument and its purposes - Google Patents
Full-automatic shifting liquid instrument and its purposes Download PDFInfo
- Publication number
- CN103846113B CN103846113B CN201410104387.5A CN201410104387A CN103846113B CN 103846113 B CN103846113 B CN 103846113B CN 201410104387 A CN201410104387 A CN 201410104387A CN 103846113 B CN103846113 B CN 103846113B
- Authority
- CN
- China
- Prior art keywords
- line slideway
- mobile
- pipetting
- liquor removing
- mobile bar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Sampling And Sample Adjustment (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Abstract
The invention provides a kind of liquor removing workstation, it includes pipetting device support and several pipetting device, and wherein pipetting device includes mobile foundation, is assemblied in the mobile bar of described mobile foundation movably；Mobile bar drive mechanism；The gear that can rotate around vertical direction；Line slideway fixes seat；And it is arranged on the pipetting head of mobile bar lower end.Present invention also offers aforementioned pipetting device.Present invention also offers described liquor removing workstation in the purposes implementing the aspects such as liquid sample-adding, liquid transfer.The pipetting device of the liquor removing workstation of the present invention can carry out horizontal or vertical movement independently, and avoid or greatly reduce the operation being lubricated it, it is to avoid pollutes.
Description
Technical field
The present invention relates to automatic fluid processing equipment.More specifically, the present invention relates to a kind of full-automatic move liquid instrument and its
In pipetting device, and implementing the purposes of the aspects such as liquid sample-adding, liquid transfer.
Background technology
Along with developing rapidly of Life Sci-Tech, faced by the research work of biochemical laboratory is increasingly complex research
Object and growing number of sample size, traditional manual mode of operation can not meet institute in high flux sample handling processes
High efficiency, accuracy and the safety required, in experimental implementation flow process, become must for part or the automatic operating of overall process
So trend.
Fully automatic liquid processing workstation is by automation mechanized operation and the ingenious biological medicine merged of liquid handling
Laboratory automation platform, can realize the automatic sample of sample, reagent distribution, ultramicron move liquid and with liquid handling phase
The vibration closed, the operation such as hatch.Can be widely applied to nucleic acid purification, gene protein order-checking, clone's rapid screening, cell training
Support, biochip sample such as prepares at the field.
Pipetting device is one of core institution of fully automatic liquid processing workstation, is used for realizing liquid and holds at normal fluid
Carry between device, extract, the action such as transfer.In the use of modern fully automatic liquid processing workstation, the most frequently used titer
Body container is the normal fluid containers such as such as 8 orifice plates, 96 orifice plates.Wherein, the normal fluid containers such as 96 orifice plates that laboratory is conventional
The minimum 9mm of adjacent holes spacing, volume about 0.5ml, 8 holes of single-row distribution.Therefore, automated fluid processing workstation, particularly
Pipetting device therein, needs in the least spatial dimension, realizes multiple in high precision and with high reproducibility, and such as eight are moved liquid
Shifting while passage or respectively is surged work.
The automated fluid processing workstation of prior art and pipetting device exist that mechanism wear is big, noise big, motion is flat
Stability is the highest, and the requirement on machining accuracy of mobile foundation chute is higher, and assembling process debugging is numerous and diverse, the defect that workload is big, and
Daily operation and maintenance are loaded down with trivial details, and easily produce pollution and the problem of corrosion in instrument internal.
Summary of the invention
The invention provides a kind of novel Automatic Workstation, overcome pipetting device in prior art and wear and tear greatly, fill
The problem that auxiliary tone examination is numerous and diverse and mechanism's overall operation flatness is poor, and it is simple to provide maintenance, does not produce the inside of pollution
Environment.
The invention provides a kind of liquor removing workstation, including:
(a) pipetting device support；
(b) several pipetting device, wherein, described pipetting device has:
Mobile foundation；
Being assemblied in the mobile bar of described mobile foundation movably, described mobile bar can do the most described shifting in vertical direction
The movement of moving base；
Mobile bar drive mechanism, including the screw mandrel be arrangeding in parallel with described mobile bar and the drive mechanism of described screw mandrel,
Described screw mandrel is connected by drive connection part and described mobile bar are fixing；
The gear being assemblied on mobile foundation and the drive mechanism of described gear, described gear can turn around vertical direction
Dynamic；
The line slideway being fixed on mobile foundation fixes seat；And it is arranged on the pipetting head of mobile bar lower end；
C () is horizontally disposed, the tooth bar with the gear of described pipetting device forms gear pair, during pinion rotation, drives
Dynamic mobile foundation moves horizontally along tooth bar；And
D () is horizontally disposed, the line slideway parallel with described tooth bar, the slide block of described line slideway and described shifting
The line slideway of liquid mechanism is fixed seat and is connected and fixing, and thus mobile foundation can be with the rail of the slide block of line slideway linearly guide rail
Road carries out the movement of horizontal direction.
In the pipetting device of the above-mentioned liquor removing workstation of the present invention, described line slideway fixes seat can be with line slideway
Slide block connects and fixing.Described line slideway can be horizontally disposed, parallel with aforementioned rack.The slide block of described line slideway
Fixing seat to be connected and fixing with described line slideway, thus line slideway is fixed seat and fixes seat with line slideway and be connected and consolidate
Fixed mobile foundation can carry out the movement of horizontal direction with the slide block of line slideway along the track of sliding catheter.
Seat is fixed at the one aspect of the present invention, the gear of described liquor removing workstation and tooth bar, and line slideway
Make when pinion rotation with the position set-up mode of line slideway, the movement driving the slide block with line slideway fixing can be realized
Pedestal moves horizontally along the slide rail direction of tooth bar and line slideway.Such as, gear and line slideway are fixed seat and are arranged on frame
The same side, corresponding tooth bar parallel juxtaposition upper and lower with line slideway.
In the one aspect of the present invention, described line slideway is fixed seat and is had the surface phase of the slide block with line slideway
With or the square surface of analogous shape and size.Such as, described line slideway fixes the height H1 of seat more than 25mm, the most greatly
In 30mm.Described line slideway fixes line slideway that seat can coordinate or use for having slide block width w more than 25mm, the most greatly
Line slideway in 30mm.
In the one aspect of the present invention, it is solid by line slideway that line slideway described in described pipetting device fixes seat
Determine block to be connected with mobile foundation.Described line slideway fixed block and above-mentioned mobile foundation can integrally castings or by modes such as screw threads
It is fixed on mobile foundation.Described line slideway fixed block is used for fixing two described line slideways and fixes seat.Generally, described directly
Line guide rail fixed block has line slideway and fixes the same or analogous width of seat (being often referred to the length of horizontal direction) and the lowest
Height (being often referred to the length of vertical direction) in twice.Such as, the height H2 of described line slideway fixed block is more than or equal to
50mm, preferably greater than or equal to 60mm.
In the one aspect of the present invention, the mobile foundation of described pipetting device has the housing of tetragon, its four
While be respectively upper beam, underbeam and two frames.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, mobile bar fills movably
It is assigned in described mobile foundation one side frame.
In the one aspect of the present invention, for assembling mobile bar described in the pipetting device of described liquor removing workstation
Frame has groove, and described slot opening is to the inner side of mobile foundation, and described mobile bar is movably mounted in described groove,
A part for mobile bar is in outside groove, i.e. highlights left frame inner surface, and this ledge moving bar can be used for mobile
The drive connection part of bar drive mechanism is fixedly connected.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, mobile bar is by being arranged on
The mobile bar sliding sleeve of frame is movably mounted in the frame on described mobile foundation, wherein said mobile bar sliding sleeve and frame
Fixing connection, described mobile bar can move in mobile bar sliding sleeve.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, mobile bar sliding sleeve is high score
Sliding sleeve prepared by sub-polymeric material.Such as easy Gus (Igus) companySeries, asDeng.These
Part prepared by polymeric material has the characteristic exempting to lubricate (self-lubricating), and has excellent soda acid resistance, shock-absorbing performance
Good, it is not necessary to seal or oil-scraping ring, convenient installation and replacement.Preferably, mobile bar sliding sleeve described in the pipetting device of the present invention is not
For metallic material parts.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, mobile bar is hollow pipe
Groove.Can be used in hollow grooved tube electric wire being installed or moving fluid catheter.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, the drive mechanism of screw mandrel is
The driving motor of described screw mandrel.Described screw mandrel is driven by driving motor.Preferably, described driving motor is servo electricity
Machine.
In the one aspect of the present invention, described screw mandrel is fixing with mobile bar even by feed screw nut and drive connection part
Connect.Such as, feed screw nut's spinning is on screw mandrel, and one end of drive connection part is fixing with mobile bar to be connected, and the other end is fixed on institute
State outside feed screw nut.Preferably, wherein said feed screw nut prepares for high molecular polymer.Choosing, the shifting liquid machine of the present invention
Feed screw nut described in structure is not metallic material parts.
In the one aspect of the present invention, described in the pipetting device of described liquor removing workstation, pipetting head has spacing
Block, and pipet stand, be connected to the conduit below pipet stand, and described conduit can connect removable liquid transfer gun head.At this
The wherein another aspect of invention, is provided with de-pipe box cylinder on conduit described in described pipetting device.In the present invention the most again
One aspect, described pipetting head has level sensor.
In the one aspect of the present invention, described liquor removing workstation also includes horizontally disposed, with described gear
Form the tooth bar of gear pair, during pinion rotation, drive mobile foundation to move horizontally along tooth bar.
In the one aspect of the present invention, described liquor removing workstation also includes horizontally disposed, with described tooth bar
Parallel line slideway, the slide block of described line slideway is fixed seat and is connected and fixes, thus mobile foundation with described line slideway
The movement of horizontal direction can be carried out with the track of the slide block of line slideway linearly guide rail.In the one aspect of the present invention,
Described mobile foundation is to fix seat (may also include line slideway fixed bit) by line slideway to be connected with the slide block of line slideway
With fixing.
In the one aspect of the present invention, wherein said gear and line slideway are fixed the position set-up mode of seat and are made
During proper pinion rotation, mobile foundation is driven to move horizontally along the slide rail direction of tooth bar and line slideway.Mobile foundation is to pass through
Line slideway is fixed seat (may also include line slideway fixed bit) and is connected with the slide block of line slideway and fixing.Such as, gear with
And line slideway fixes seat and is disposed therein the same side of a frame, corresponding tooth bar parallel juxtaposition upper and lower with line slideway.
In the one aspect of the present invention, described in described pipetting device, pipetting head has limited block, and pipet
Frame, is connected to the conduit below pipet stand, and described conduit can connect replaceable liquid transfer gun head.The present invention wherein another
Aspect, described conduit is provided with de-pipe box cylinder.In the wherein another aspect of the present invention, wherein said pipetting head has liquid level
Detector.Described level sensor may be provided at below pipet stand.
In the one aspect of the present invention, described liquor removing workstation has several (such as four or eight) aforementioned shifting liquid
Mechanism, two or more in wherein said several pipetting devices assemble side by side, two or two of described assembling arranged side by side
The mobile bar of above pipetting device arranges point-blank, and two or more pipetting devices of described assembling arranged side by side
Gear and same tooth bar form gear pair.The wherein another aspect of the present invention, two or two of described assembling arranged side by side
In individual above pipetting device, the line slideway of the mobile foundation of two pipetting devices fixes two of seat and same line slideway
Slide block connects.Such as, fix seat by the line slideway on adjacent two mobile foundations and be separately fixed at the straight line of mobile foundation
Top half on guide rail fixed block or the latter half, two movements in several pipetting devices of the most described assembling arranged side by side
Pedestal can be connected with two slide blocks of same line slideway respectively.Described gear and tooth bar, and line slideway fix seat and
The position set-up mode of line slideway makes when pinion rotation, can realize the mobile base driving the slide block with line slideway fixing
Seat moves horizontally along the slide rail direction of tooth bar and line slideway.
In the one aspect of the present invention, described liquor removing workstation includes four or eight described pipetting devices.At bag
Including in the liquor removing workstation of eight described pipetting devices, described eight pipetting devices are divided into two groups be arranged in parallel, often group four
Pipetting device assembles side by side, and often the gear of four pipetting devices of group forms gear pair with same tooth bar.In the present invention wherein
Another aspect, in four pipetting devices of described often group, the line slideway of the mobile foundation of two pipetting devices fixes seat with same
Two slide blocks of individual line slideway connect.Such as, fix seat by the line slideway on adjacent two mobile foundations to fix respectively
Top half on the line slideway fixed block of mobile foundation or the latter half, four shifting liquid of the most described assembling arranged side by side
Two mobile foundations in mechanism can be connected with two slide blocks of same line slideway respectively.Described gear and tooth bar, and
Line slideway is fixed the position set-up mode of seat and line slideway and is made when pinion rotation, can realize driving and line slideway
The mobile foundation that slide block is fixed moves horizontally along the slide rail direction of tooth bar and line slideway.In the liquor removing workstation of the present invention,
The mobile bar of four pipetting devices of described often group arranges point-blank, interlocks with the mobile bar of another four pipetting devices of group
Arrange so that the liquid transfer gun head of eight described pipetting devices can arrange point-blank.
In the one aspect of the present invention, described liquor removing workstation also includes other detection device or container, such as, note
Penetrate pump, heating plate, agitator, microplate reader, PCR instrument, handgrip mechanism, and various receiving sample or the container of reagent, such as trace
Centrifuge tube, centrifuge tube, PCR microwell plate, deep-well plates, micro-porous filtration plate, pipe support etc..
In the one aspect of the present invention, additionally provide a kind of aforesaid pipetting device.In one of them of the present invention
Aspect, additionally provides a kind of multi-channeled transposition arrangement using described pipetting device, and described multi-channeled transposition arrangement is equipped with two
Individual, four or eight described pipetting devices.
The pipetting device of the present invention, device and instrument may be implemented in each pipetting device in running and carry out vertical or water independently
Flat movement, and integrally-built layout is more reasonable, space definitely, the difficulty of its assembling and setting and complexity
Property is the most greatly reduced.Additionally, the pipetting device of the present invention uses self-lubricating, non-maintaining macromolecule polymer material
The sliding sleeve of the preparation mobile bar for fixing and make it slide wherein, the slip in high molecular polymer sliding sleeve of the hollow square tube
Smooth-going, soft, noise is little, and avoid or reduces the operation being lubricated it, it is to avoid oils lubricator is to moving liquid
The pollution that operation is likely to cause.Additionally, what the pipetting device of the present invention used is used for realizing the motion of pipetting head vertical direction
Lead screw pair, with driven by servomotor leading screw, can overcome the defect that in prior art, mechanical vibration are big, unstable.And wherein silk
Thick stick nut takes gap-eliminating structure, can eliminate most of mechanical clearance of motion between feed screw nut and leading screw, can realize further
More accurate transmission, thus realize the pipetting that pipetting head is finer.Wherein, feed screw nut is alternatively polymeric material system
Standby, thus, drive the mechanism that moves of pipetting head vertical direction can avoid or reduce the operation that it is lubricated, it is to avoid oil
The pollution that pipetting is likely to cause by lipid lubricator.
Accompanying drawing explanation
Fig. 1 is local interior's installation drawing of the liquor removing workstation of the preferred embodiment of the present invention；
Fig. 2 is the axonometric chart of the pipetting device of the liquor removing workstation of the preferred embodiment of the present invention；
Fig. 3 is the sectional view of the pipetting device of the liquor removing workstation of the preferred embodiment of the present invention；
Fig. 4 is the subassembly schematic diagram of the pipetting device of the liquor removing workstation of the preferred embodiment of the present invention；
Fig. 5 is the schematic perspective view of another angle of part-structure of the liquor removing workstation of the preferred embodiment of the present invention.
In accompanying drawing, each labelling is respectively as follows:
1 mobile foundation
2 square tube sliding sleeves
201 square tube sliding sleeves are protruding
3 screw mandrel shaft couplings
4 screw mandrels
6 feed screw nuts
7 hollow square bars
8 gear couplings
9 chassis backplane
11 motor cabinets
12 gear drive motor
13 move bar drives motor
14 gear-bearings
15 gear shafts
16 gears
17 drive connection parts
18 top boards
19 base plates
21 upper beams
22 underbeams
23 left frames
231 left frame grooves
24 left frames
25 pipet stands
26 conduits
27 pipet stands
28 take off pipe box cylinder
30 liquid transfer gun heads
31 limited blocks
33 cablings walk pipe joint
34 line slideways fix seat
35 line slideway fixed blocks
36 circuit board box
40 line slideways
41 line slideway slide rails
42 straight-line guide rail slide blocks
43 tooth bars
Detailed description of the invention
For a better understanding and interpretation of the present invention, the present invention is described in further detail below with reference to accompanying drawings.
Fig. 1 is local interior's installation drawing of liquor removing workstation according to a preferred embodiment of the present invention.
The liquor removing workstation of the present invention typically has eight for implementing liquid sample-adding, the pipetting device 38 of liquid transfer.
Described eight pipetting devices are divided into two groups be arranged in parallel, and often four pipetting devices of group assemble side by side.Fig. 1 illustrates the shifting of the present invention
The interior section device schematic diagram of liquid work station, it includes the device of above-mentioned one group of four pipetting device assembled side by side.Described
Pipetting device has mobile foundation 1, and described mobile foundation has the housing of tetragon.Described pipetting device also has movably
Vertically-mounted mobile bar on a side frame of mobile foundation 7 and be arranged on this pipetting head 30 moving bar lower end.Described shifting
Lever can do moving up and down of the most described mobile foundation in vertical direction in described frame.Described mobile bar is driven to do phase
The drive mechanism moving up and down described mobile foundation includes being assemblied on described mobile foundation, parallel with described mobile bar
Screw mandrel 4.Pipetting head be sense for liquid, carry, the mechanism of the function such as absorption, generation can be moved up and down with described mobile bar
Move up and down, it is achieved process the function of the fluid sample being arranged in the vessel ware below pipetting head.
Described pipetting device also has the gear 16 that can rotate being assemblied in outside mobile foundation frame, institute around vertical direction
State gear and can form gear pair with horizontally disposed tooth bar 43, during pinion rotation, drive mobile foundation to move horizontally along tooth bar.Institute
State pipetting device also to have and be fixed on mobile foundation, for being attached with the slide block 42 of line slideway and fixing straight line is led
Seat fixed by rail, and thus mobile foundation can move horizontally along the realization of sliding of horizontally disposed line slideway 40.Gear 16 and tooth bar 43,
And line slideway fixes the position set-up mode of seat 34 and line slideway 40 and makes when gear 16 rotates, can realize driving with
The mobile foundation that the slide block of line slideway is fixed moves horizontally along the slide rail direction of tooth bar and line slideway.
The mobile bar of four pipetting devices of often group of the liquor removing workstation of the present invention arranges point-blank, with another group
The mobile bar of four pipetting devices is crisscross arranged so that the liquid transfer gun head of eight described pipetting devices can be arranged in straight line
On.
In preferred embodiment as described in Figure, the liquor removing workstation of the present invention often group four pipetting devices gear with
Same tooth bar formed gear pair, the line slideway on the most adjacent two mobile foundations fix seat 34 respectively with same straight line
Two slide blocks of guide rail connect, and the most often four pipetting devices of group and two line slideways connect.A described tooth bar and described
Article two, line slideway be arranged in parallel up and down.
The liquor removing workstation of the present invention also can have casing (not shown) and support the support of aforementioned pipetting device.Support can
Including for supporting and/or set up the pillar of pipetting device, crossbeam and backboard etc..As it is shown in figure 1, a described tooth bar 43 and institute
State two line slideways about 40 to be arranged in parallel, be fixed on backboard 9.Backboard 9 can be fixed on chassis sidewall or be fixed on frame
It is located on the crossbeam of internal body.
Fig. 2 is the schematic perspective view of pipetting device according to a preferred embodiment of the present invention.Fig. 3 is the one of the present invention
The internal view of the pipetting device of individual preferred embodiment.
As shown in Figures 2 and 3, this pipetting device has mobile foundation, and described mobile foundation has the housing of tetragon；Institute
State pipetting device and also there is the most vertically-mounted movement of (left frame 23 as shown) on a side frame of mobile foundation
Bar and be arranged on this pipetting head moving bar lower end, described mobile bar can do relatively described in vertical direction in described frame
Moving up and down of mobile foundation, pipetting head be sense for liquid, carry, the mechanism of the function such as absorption, can be with described mobile bar
Move up and down, it is achieved process the function of fluid sample being arranged in the vessel ware below pipetting head；Institute
State pipetting device and also have for driving described mobile bar to do the drive mechanism moved up and down of the most described mobile foundation, including
Being assemblied on described mobile foundation, the screw mandrel parallel with described mobile bar and the driving motor of described screw mandrel, described screw mandrel leads to
Connector of overdriving is fixing with described mobile bar to be connected；Described pipetting device also have be assemblied in outside mobile foundation frame can
The gear rotated around vertical direction and the drive mechanism of described gear, described gear can form gear with horizontally disposed tooth bar
Pair, during pinion rotation, drives mobile foundation to move horizontally along tooth bar；Described pipetting device also has and is fixed on mobile foundation,
Line slideway for being attached with the slide block of line slideway and fix fixes seat, and thus mobile foundation can be along horizontally disposed
Line slideway slip realization moves horizontally.
In the pipetting device of the preferred embodiment of the present invention shown in Fig. 2, described mobile foundation is cuboid parts, has
The housing of tetragon, its four limits are respectively upper beam 21, underbeam 22, left frame 23 and left frame 24.Described pedestal is generally by can
Alleviator weight and reduce liquid attachment the metal material such as material such as aluminium or rustless steel make.Described frame has necessarily
Thickness, to provide supporting function to motor, for accommodating the devices such as the circuit board box that controls the equipment such as motor, and may be used for
Accommodate and support aforementioned mobile bar.Such as, described frame can have and the motor width (diameter or rectangular of such as column type motor
The width etc. of build motor) similar thickness, or have more than the width of described mobile bar (such as cylindrical mobile bar straight
Footpath or square move the width etc. of bar) thickness.In the one aspect of the present invention, described frame has more than 0.5cm's
Thickness.Use the design with frame, the advantages such as component weight can be reduced.In other embodiments, mobile foundation also may be used
Not think the cuboid parts with hollow space.Now, the part on its four limits is also equal to the housing of aforementioned tetragon, i.e.
" upper beam, underbeam, left frame and left frame ".
In the diagram preferred embodiment of the present invention, left frame 23 is used for arranging and aforementioned does the most described shifting in described frame
The mobile bar 7 moved up and down of moving base.In diagram preferred embodiment, left frame 23 is hollow structure, described mobile bar 7
It is movably mounted in described left frame.In diagram preferred embodiment, left frame 23 has groove, described slot opening
To the inner side (i.e. in the face of the side of left frame) of mobile foundation, described mobile bar is movably mounted in described groove, mobile
A part for bar is in outside groove, i.e. highlights left frame inner surface, and this ledge moving bar can be used for moving with driving
The drive mechanism that bar moves up and down is fixedly connected.
As shown in Figures 2 and 3, for drive described mobile bar do in left frame the most described mobile foundation on move down
Dynamic drive mechanism includes being assemblied on described mobile foundation, driving of the screw mandrel 4 parallel with described mobile bar and described screw mandrel
Galvanic electricity machine 13.Preferably, described driving motor 13 is servomotor.Described driving motor 13 is connected with screw mandrel 4 by shaft coupling 3
And transmission.The two ends up and down of described screw mandrel are limited between the upper beam of mobile foundation and underbeam by bearing.Driving motor 13 can
It is arranged on the top of described screw mandrel.In diagram the preferred embodiments of the present invention, the upper beam of described mobile foundation has groove,
Wherein can accommodate shaft coupling 3, additionally be provided above top board 18 at upper beam, described driving motor 13 vertical rack is located at described top board 18
Top.Described top board can have length and width same or analogous with upper beam.Described top board also can have the length big compared with upper beam
Degree, except can be used for setting up described driving motor 13, it may also be used for sets up and accommodates the circuit board box of the equipment such as control motor (such as figure
Circuit board box 29 in 1) etc. device.This design can be greatly saved the automatic moving liquid instrument of the pipetting device using the present invention
Inner space, it is simple to electric wire, move fluid catheter erection.
Described screw mandrel 4 is connected by feed screw nut 6 and drive connection part 17 are fixing with mobile bar 7.Wherein, feed screw nut 6 spinning
On screw mandrel, one end of drive connection part 17 is connected by the modes such as screw are fixing with mobile bar 7, and the other end can be by spinning mode
It is fixed on outside feed screw nut 6.When screw mandrel rotates under driving motor 13 to drive, drive connection part 17 can be at mobile foundation
Depth of beam up and down in the range of move up and down, thus drive mobile bar to move up and down.In the one aspect of the present invention, institute
State feed screw nut and can take gap-eliminating structure, eliminate most of mechanical clearance of motion between feed screw nut and leading screw.At its of the present invention
In an aspect, described feed screw nut use macromolecule polymer material prepare.Such as easy Gus (Igus) company
Series, as WithDeng.
Part prepared by these polymeric materials has the characteristic exempting to lubricate (self-lubricating), and has excellent soda acid resistance, shock-absorbing
Performance is good, it is not necessary to seal or oil-scraping ring, convenient installation and replacement.
The shown mobile bar of the pipetting device of the present invention the most vertically (i.e. parallel with frame direction) is solid
It is scheduled on mobile foundation.Preferably, shown mobile bar is removably fixed in one of them frame of mobile foundation.Such as,
It is movably mounted in the frame on described mobile foundation by being arranged on the mobile bar sliding sleeve at the upper and lower two ends of frame, Qi Zhongsuo
Stating that mobile bar sliding sleeve and frame are fixing to be connected, described mobile bar can move in movement bar sliding sleeve.In the illustrated embodiment, described
Mobile bar is square pole 7, is removably affixed at the two ends up and down of mobile foundation with left frame 23 by square tube sliding sleeve 2.Fig. 4 is
Described square pole 7, square tube sliding sleeve 2 and the annexation schematic diagram of left frame 23.As shown in Figure 4, square tube sliding sleeve is fixed on the left side
The inside of frame 23 wherein one end (upper end such as illustrated, it also has same structure in lower end) is (such as by square tube sliding sleeve
On projection 201 coordinate with the groove 231 at left frame edge), square pole 7 is slidably fitted within square tube sliding sleeve 2.At this
Bright one aspect, described square tube sliding sleeve uses the polymeric material of self-lubricating to prepare.Such as easily Gus (Igus) company
'sSeries, asWithDeng.These polymeric materials have excellent soda acid resistance, and shock-absorbing performance is good, it is not necessary to seal or frizing
Ring, convenient installation and replacement.
In the illustrated embodiment, shown mobile bar is the square pole 7 of hollow.Described mobile bar uses hollow grooved tube, available
In installing electric wire or moving fluid catheter etc..Such as, can be used for cabling, be connected including with conduit, for the conveying of liquid and extracting
Catheter, and the electric wire that all parts and mechanism use, the cable of such as level sensor, the electric wire etc. of motor.Square
The top of bar 7, can arrange cabling and walk pipe joint 33.
The pipetting device of the present invention also have be arranged on mobile foundation (such as scuncheon or outside) can be around vertically
The gear 16(that direction rotates rotates the most in the horizontal plane).In the illustrated embodiment, described gear is provided in assembling described shifting
The outside of the opposite side frame of the frame of lever 7.Described gear can form gear pair with horizontally disposed tooth bar, is achieved in tooth
When wheel rotates, mobile foundation is driven to move horizontally along tooth bar.The rotation of gear is driven by gear drive motor 12.Gear drives electricity
Machine 12 may be provided at above gear, such as, be vertically set on the motor cabinet 11 being fixed on outside the frame of mobile foundation.Gear
Drive motor 12 by shaft coupling 8 to gear 16 transmission.Preferably, described gear drive motor is servomotor.
The pipetting device of the present invention also has and is fixed on mobile foundation, for being fixed with the slide block of line slideway
Line slideway fixes seat 34.In the one aspect of the present invention, described line slideway is fixed seat 34 and is fixed on mobile foundation limit
Frame (left frame 24 such as illustrated) outside.Line slideway fixes seat, and to have the surface of slide block with line slideway same or like
The square surface of size.In the one aspect of the present invention, described line slideway is fixed the height H1 of seat and is not less than
25mm, preferably not less than 30mm.The pipetting device of the present invention or use the automatic moving liquid instrument of described pipetting device to coordinate
Or the line slideway used is that the slide block with the slide block i.e. line slideway of width w(is in the direction vertical with the slide rail of line slideway
On length) not less than the line slideway of 25mm, preferably not less than 30mm.Use the line slideway with above-mentioned slide block width
And/or the line slideway of above-mentioned height fixes seat, substantially increase the stability that pipetting device of the present invention runs unexpectedly.
The described line slideway of the pipetting device of the present invention is fixed the slide block of seat and line slideway and can be fixed by modes such as screws,
Thus mobile foundation can linearly move by slide.At the pipetting device of the present invention or use the shifting of pipetting device of the present invention
In liquid instrument, line slideway is horizontally disposed with, and is achieved in mobile foundation and linearly moves horizontally in guide rail direction.
In the one aspect of the present invention, the pipetting device of the present invention has line slideway fixed block 35, described straight line
Guide rail is fixed seat 34 and can be connected with mobile foundation on described line slideway fixed block 35 by being fixed on.Described line slideway is solid
Determine block 35 and mobile foundation can integrally casting, or be fixed on mobile foundation by modes such as screws.A kind of enforcement wherein
In mode, line slideway fixed block 35 can be a part for frame.At the one aspect of the present invention, described line slideway
The height of fixed block fixes the height H2 of seat more than or equal to the line slideway of twice.Preferably, described line slideway fixed block
Height not less than 50mm, preferably not less than 60mm.Line slideway fixes seat 34 can be fixed on the upper of line slideway fixed block 35
Half part or the latter half.
In the pipetting device of the preferred embodiment of the present invention, in preferred embodiment the most shown in the drawings, can turn around vertical axis
Dynamic gear 16 and line slideway are fixed seat 34 and are arranged on the same outside of frame of mobile foundation, outside left frame as shown
Side.As shown in Fig. 1 or Fig. 5, form the tooth bar 43 of gear pair with gear 16 and fix the straight line that seat 34 is connected with line slideway and lead
Rail 40 can be arranged in parallel.Gear 16 and line slideway are fixed the position set-up mode of seat 34 and are made when gear 16 rotates, can
Realize driving the mobile foundation fixed with the slide block of line slideway to move horizontally along the slide rail direction of tooth bar and line slideway.Preferably
, gear 16 and line slideway are fixed seat 34 and are arranged on the same side of frame, corresponding tooth bar 43 and line slideway about 40
Parallel juxtaposition.Thus, the inner space of the automatic moving liquid instrument of the pipetting device using the present invention can be greatly saved.At other
In embodiment, gear 16 and line slideway fix seat 34 can also be arranged on other suitable position of mobile foundation, can
Realize driving the mobile foundation fixed with the slide block of line slideway to move horizontally along the slide rail direction of tooth bar and line slideway.
The pipetting device of the described preferred embodiment of the present invention also has the pipetting head being fixedly mounted on mobile bar 7 lower end.Move
Liquid head is the mechanism for functions such as liquid sensing, extractings, includes the parts realizing these functions.In the illustrated embodiment,
This pipetting head includes pipet stand 27, de-pipe box cylinder 28, conduit 26, limited block 31, liquid transfer gun head 30 and liquid level detector 25.Its
In, pipet stand 27 is used for setting up liquid level detector 25 and conduit 26, and conduit 26 is used for connecting liquid transfer gun head, limited block 31.De-
Pipe box cylinder 28 reaches, for realizing liquid transfer gun head and separating with conduit, the purpose automatically changed.Due to liquid transfer gun head and conduit
Combination closely, de-pipe box cylinder needs to realize liquid transfer gun head in the least distance range and separates with conduit.The present invention
The design of pipetting device pipetting head make de-pipe box cylinder can reach this purpose.Liquid level detector can be used for sensing pipetting head
Distance between liquid and liquid transfer gun head in the normal fluid container (such as 8 orifice plates, 96 orifice plates) of lower section, signal is fed back to from
Dynamic work station, and the most under program signal is fed back to the instrument of manipulation pipetting device.
The full-automatic liquor removing workstation of the present invention can assemble four or eight described pipetting devices.Described four or eight institutes
Stating pipetting device can independent horizontal or the movement of vertical direction, it is possible to synchronize occurred level or the movement of vertical direction, and adjacent
Two pipetting devices there is identical horizontal range change so that adjacent liquid transfer gun head occurs identical horizontal range to become
Change.
Fig. 5 is the three-dimensional signal of another angle of part-structure of the full-automatic liquor removing workstation of the preferred embodiment of the present invention
Figure.
The full-automatic liquor removing workstation of the present invention generally assembles four or eight described pipetting devices, and described eight are moved liquid machine
Structure is divided into parallel two group, and often four pipetting devices of group assemble side by side, and often the mobile bar of four pipetting devices of group is arranged in one
On straight line, the line slideway on the mobile foundation of adjacent two pipetting devices is fixed seat 34 and is separately fixed at line slideway fixed block
Top half on 35 or the latter half, the mobile foundation of two in the most same group of four pipetting devices can be respectively with same
Two slide blocks of one line slideway connect (fixing seat and line slideway fixed bit by line slideway), thus are greatly saved and adopt
Inner space with the automatic moving liquid instrument of the pipetting device of the present invention.The full-automatic liquor removing workstation of the present invention often organizes four
The mobile bar of individual pipetting device arranges point-blank, is crisscross arranged with the mobile bar of another four pipetting devices of group so that
The liquid transfer gun head of eight described pipetting devices can arrange point-blank.
The multi-channeled transposition arrangement of eight pipetting device formation can process the marks such as 8 orifice plates, 24 orifice plates, 96 orifice plates easily
Quasi-liquid container.The most each pipetting device can move up and down independently.
The invention described above liquor removing workstation can be used for sensing liquid, detect, draw and the operation such as discharge, thus real
The transfer of existing liquid.
Present invention also offers the pipetting device of the invention described above, multi-channeled transposition arrangement or full-automatic liquor removing workstation to use
In liquid being sensed, detect, draw and discharging, thus realize the purposes of the transfer of liquid.
In operation, the whole workflow of the liquor removing workstation of the invention described above preferred embodiment is as follows:
Carry out the absorption of liquid needing the normal fluid container (such as 8 orifice plates, 96 orifice plates) to below pipetting head or put
When going out action, pipetting device is made to move to above normal fluid container under program.Under liquid level detector sensing pipetting head
Distance between normal fluid liquid in containers and the liquid transfer gun head of side, feeds back to control system by signal, can be by mobile bar
Driving motor 13 to make screw mandrel rotate, screw mandrel makes vertical at mobile foundation left frame of mobile bar 7 by drive connection part 17
Do in hole and move vertically, thus realize moving up and down of fluid suction head.Need to carry out the shifting in horizontal direction when moving liquid-based seat
Time dynamic, gear drive motor 12 drives the rotation in gear 16 occurred level direction, thus drives mobile foundation by leading with straight line
The slide block of rail is fixed, and can linearly move horizontally by guide rail.
The design of the pipetting device of the present invention makes in using its liquor removing workstation that each pipetting device can be the most only
On the spot carrying out horizontal or vertical movement, there is no annexation from each other. such structure arranges and makes integrally-built cloth
Office is more reasonable, and definitely, difficulty and the complexity of its assembling and setting are the most greatly reduced space.Carry out
During the maintenance of pipetting device, only pipetting channel maintenance that wherein certain damages need to be changed, it is not necessary to relate to other passages
Dismounting.
Additionally, the liquor removing workstation of the present invention controls the parts many employings self-lubricating in the mechanism that pipetting head moves, exempts from
Prepared by the high molecular polymer safeguarded, it is to avoid or greatly reduce the operation being lubricated it, it is to avoid oils lubricator
The pollution that pipetting is likely to cause.
Although example embodiment and advantage thereof about the present invention are described in detail, it should be understood that without departing from the present invention
Spiritual and defined in the appended claims protection domain in the case of, these embodiments can be carried out various change, replacement
And amendment.For other examples, those of ordinary skill in the art is it should be readily appreciated that within keeping scope
Meanwhile, the order of processing step can change.
Additionally, the range of application of the present invention is not limited to the technique of specific embodiment described in description, mechanism, system
Make, material composition, means, method and step.From the disclosure, will be easily as those of ordinary skill in the art
Ground understands, for the technique having existed at present or will having developed later, mechanism, manufacture, material composition, means, method or
Step, wherein they perform the knot that the function that is substantially the same of corresponding embodiment or acquisition with present invention description are substantially the same
Really, they can be applied according to the present invention.Therefore, claims of the present invention are intended to these technique, mechanism, system
Make, material composition, means, method or step are included in its protection domain.
Claims (25)
1. a liquor removing workstation, including:
(a) pipetting device support；
(b) several pipetting device, wherein, described pipetting device has:
Mobile foundation (1),
Being assemblied in the mobile bar (7) of described mobile foundation (1) movably, described mobile bar can do relatively described in vertical direction
The movement of mobile foundation；
Mobile bar drive mechanism, including the screw mandrel (4) be arrangeding in parallel with described mobile bar (7) and the driving machine of described screw mandrel
Structure, described screw mandrel (4) is connected by drive connection part (17) and described mobile bar (7) are fixing；
The gear (16) being assemblied on mobile foundation (1) and the drive mechanism of described gear, described gear (16) can be around vertically
Direction rotates；
The line slideway being fixed on mobile foundation (1) fixes seat (34)；And
It is arranged on the pipetting head of mobile bar (7) lower end；
C () is horizontally disposed, with the tooth bar (43) that the gear (16) of described pipetting device forms gear pair, pinion rotation
Time, drive mobile foundation to move horizontally along tooth bar；And
D () is horizontally disposed, the line slideway parallel with described tooth bar, the slide block of described line slideway and described shifting liquid machine
The line slideway of structure is fixed seat (34) and is connected and fix, and thus mobile foundation can be with the rail of the slide block of line slideway linearly guide rail
Road carries out the movement of horizontal direction.
2. the liquor removing workstation described in claim 1, wherein said mobile foundation has the housing of tetragon, described mobile bar
(7) described mobile foundation (1) side frame it is assemblied in movably.
3. the liquor removing workstation described in claim 2, the wherein said frame for assembling mobile bar (7) has groove, described
Slot opening is to the inner side of mobile foundation, and described mobile bar is movably mounted in described groove, at a part for mobile bar
Outside groove, i.e. highlighting left frame inner surface, this ledge moving bar can be used for and the driving of mobile bar drive mechanism
Connector (17) is fixedly connected.
4. the liquor removing workstation described in claim 3, wherein said mobile bar can move by being arranged on the mobile bar sliding sleeve of frame
Being assemblied in the frame on described mobile foundation, wherein said mobile bar sliding sleeve is fixing with frame to be connected, described mobile bar dynamicly
Can move in mobile bar sliding sleeve.
5. the liquor removing workstation described in claim 4, wherein said mobile bar sliding sleeve is high molecular polymer sliding sleeve.
6. the liquor removing workstation described in claim 5, wherein said mobile bar is hollow grooved tube.
7. the liquor removing workstation described in claim 1, the drive mechanism of wherein said screw mandrel includes the driving motor of described screw mandrel.
8. the liquor removing workstation described in claim 7, the driving motor of wherein said screw mandrel is servomotor.
9. the liquor removing workstation described in claim 1, wherein said screw mandrel (4) passes through feed screw nut (6) and drive connection part
(17) fixing with mobile bar (7) be connected, wherein, feed screw nut (6) spinning on screw mandrel, one end of drive connection part (17) and shifting
Lever 7 is fixing to be connected, and the other end is fixed on described feed screw nut (6) outside.
10. the liquor removing workstation described in claim 9, wherein said feed screw nut is high molecular polymer feed screw nut.
Liquor removing workstation described in 11. claim 1, wherein said line slideway fixes seat (34) by line slideway fixed block
(35) it is connected with mobile foundation.
Liquor removing workstation described in 12. claim 1, wherein said line slideway fixes the height H1 of seat (34) more than 25mm.
Liquor removing workstation described in 13. claim 12, wherein said line slideway fixes the height H1 of seat (34) more than 30mm.
Liquor removing workstation described in 14. claim 11, the height H2 of wherein said line slideway fixed block is more than or equal to
50mm。
Liquor removing workstation described in 15. claim 14, the height H2 of wherein said line slideway fixed block is more than or equal to
60mm。
The liquor removing workstation of 16. claim 1, wherein said pipetting head has limited block, and pipet stand (25), is connected to
Conduit (26) below pipet stand, described conduit can connect removable liquid transfer gun head (30).
The liquor removing workstation of 17. claim 16, wherein said conduit is provided with de-pipe box cylinder (28).
The liquor removing workstation of 18. claim 16, wherein said pipetting head has level sensor.
Liquor removing workstation according to any one of 19. claim 1-18, two or two in wherein said several pipetting devices
Individual above assembling side by side, the mobile bar of two or more pipetting devices of described assembling arranged side by side arranges point-blank,
And the gear of two or more pipetting devices of described assembling arranged side by side forms gear pair with same tooth bar.
Liquor removing workstation described in 20. claim 19, in two or more pipetting devices of wherein said assembling arranged side by side
The line slideway of the mobile foundation of two pipetting devices is fixed seat (34) and is connected with two slide blocks of same line slideway.
Liquor removing workstation described in 21. claim 19, in two or more pipetting devices of wherein said assembling arranged side by side
The line slideway of the mobile foundation of adjacent two pipetting devices is fixed seat (34) and is separately fixed on its line slideway fixed block
Top half or the latter half.
Liquor removing workstation described in 22. claim 19, it includes four or eight described pipetting devices.
Liquor removing workstation described in 23. claim 22, it includes that eight described pipetting devices, described eight pipetting devices are divided into
Two groups be arranged in parallel, often four pipetting devices of group assemble side by side, often organize gear and the same rack-shaped of four pipetting devices
The line slideway of the mobile foundation of two pipetting devices in gear pair, and four pipetting devices of described often group is become to fix seat with same
Two slide blocks of one line slideway connect.
Liquor removing workstation described in 24. claim 23, the line slideway on the most adjacent two mobile foundations fixes seat (34)
It is separately fixed at the top half on line slideway fixed block (35) or the latter half.
Liquor removing workstation described in 25. claim 23, the most mobile bar of four pipetting devices of group is arranged in straight line
On, it is crisscross arranged with the mobile bar of another four pipetting devices of group so that the liquid transfer gun head of eight described pipetting devices can arrange
Point-blank.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410104387.5A CN103846113B (en) | 2013-11-06 | 2014-03-20 | Full-automatic shifting liquid instrument and its purposes |
| US15/034,373 US20160266162A1 (en) | 2013-11-06 | 2014-05-11 | Fully-automatic pipetting instrument and use thereof |
| PCT/CN2014/090402 WO2015067180A1 (en) | 2013-11-06 | 2014-11-05 | Fully-automatic pipetting instrument and use thereof |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013105445878 | 2013-11-06 | ||
| CN201310544587.8 | 2013-11-06 | ||
| CN201310544587.8A CN103551216A (en) | 2013-11-06 | 2013-11-06 | Full automatic liquid relief instrument and application thereof |
| CN201410104387.5A CN103846113B (en) | 2013-11-06 | 2014-03-20 | Full-automatic shifting liquid instrument and its purposes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103846113A CN103846113A (en) | 2014-06-11 |
| CN103846113B true CN103846113B (en) | 2016-08-31 |
Family
ID=50005669
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310544587.8A Pending CN103551216A (en) | 2013-11-06 | 2013-11-06 | Full automatic liquid relief instrument and application thereof |
| CN201410104387.5A Expired - Fee Related CN103846113B (en) | 2013-11-06 | 2014-03-20 | Full-automatic shifting liquid instrument and its purposes |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310544587.8A Pending CN103551216A (en) | 2013-11-06 | 2013-11-06 | Full automatic liquid relief instrument and application thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN103551216A (en) |
| HK (1) | HK1198962A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106350438A (en) * | 2016-10-27 | 2017-01-25 | 上海理工大学 | Device for improving flux of monoclonal selecting instrument |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160266162A1 (en) * | 2013-11-06 | 2016-09-15 | Degree Of Freedom Scientific Machine Co., Ltd. | Fully-automatic pipetting instrument and use thereof |
| CN103846114B (en) * | 2014-03-21 | 2016-08-31 | 北京自由度科学机器有限公司 | Full-automatic liquor removing workstation and its purposes |
| DE102014108688A1 (en) * | 2014-06-20 | 2015-12-24 | Hamilton Bonaduz Ag | Pipetting device with modular pipetting head |
| CN110361230B (en) * | 2018-04-09 | 2021-12-14 | 冷泉港生物科技股份有限公司 | Automatic liquid injection method and device for detecting monogenic genetic diseases |
| CN109142708B (en) * | 2018-09-02 | 2023-01-24 | 广州源起健康科技有限公司 | Full-automatic magnetic bead time-resolved fluorescence immunoassay appearance |
| CN110849701B (en) * | 2019-11-04 | 2023-02-28 | 山东见微生物科技有限公司 | Sample processing apparatus |
| WO2022021377A1 (en) * | 2020-07-31 | 2022-02-03 | 杭州九洋生物科技有限公司 | Pipette and pipetting method |
| CN112300911A (en) * | 2020-10-27 | 2021-02-02 | 广州和实生物技术有限公司 | Nucleic acid detector and nucleic acid detection method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5055263A (en) * | 1988-01-14 | 1991-10-08 | Cyberlab, Inc. | Automated pipetting system |
| CN101596469A (en) * | 2009-07-03 | 2009-12-09 | 烟台艾德康生物科技有限公司 | Multi-channel loading device |
| CN203170349U (en) * | 2013-01-15 | 2013-09-04 | 北京金麦格生物技术有限公司 | Liquid transferring mechanism |
| CN203173796U (en) * | 2013-01-15 | 2013-09-04 | 北京金麦格生物技术有限公司 | Liquid transferring device |
-
2013
- 2013-11-06 CN CN201310544587.8A patent/CN103551216A/en active Pending
-
2014
- 2014-03-20 CN CN201410104387.5A patent/CN103846113B/en not_active Expired - Fee Related
- 2014-12-09 HK HK14112362.9A patent/HK1198962A1/en not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5055263A (en) * | 1988-01-14 | 1991-10-08 | Cyberlab, Inc. | Automated pipetting system |
| CN101596469A (en) * | 2009-07-03 | 2009-12-09 | 烟台艾德康生物科技有限公司 | Multi-channel loading device |
| CN203170349U (en) * | 2013-01-15 | 2013-09-04 | 北京金麦格生物技术有限公司 | Liquid transferring mechanism |
| CN203173796U (en) * | 2013-01-15 | 2013-09-04 | 北京金麦格生物技术有限公司 | Liquid transferring device |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106350438A (en) * | 2016-10-27 | 2017-01-25 | 上海理工大学 | Device for improving flux of monoclonal selecting instrument |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1198962A1 (en) | 2015-07-24 |
| CN103551216A (en) | 2014-02-05 |
| CN103846113A (en) | 2014-06-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103846113B (en) | Full-automatic shifting liquid instrument and its purposes | |
| CN103846114B (en) | Full-automatic liquor removing workstation and its purposes | |
| CN103894249B (en) | For automatically moving pipetting device and its purposes of liquid instrument | |
| CN103861671A (en) | Full-automatic pipetting mechanism and instrument | |
| CN101975708B (en) | Weight loading ring-piece type corrosive wear tester | |
| CN203874790U (en) | Full-automatic pipetting workstation | |
| CN101975709B (en) | Bolt loading ring-block type corrosive wear testing machine | |
| CN101180544A (en) | High-speed automatic dispensing device with replaceable dispensing head and dispensing station | |
| CN203778091U (en) | Liquid transfer mechanism for fully-automatic liquid transfer instrument | |
| CN203778092U (en) | Full-automatic pipetting mechanism | |
| CN101982779A (en) | Automatic sampling mechanism of analytical instrument | |
| CN110007103A (en) | A kind of compact independence multichannel liquor removing workstation | |
| WO2015067180A1 (en) | Fully-automatic pipetting instrument and use thereof | |
| CN109262284A (en) | A kind of spherical tank boring device | |
| CN203170349U (en) | Liquid transferring mechanism | |
| CN207204137U (en) | A kind of spacing adjusting device | |
| CN106869920B (en) | The abrasion in-situ observation experimental rig of continuous pipe operation under dummy level well sand deposition | |
| CN203874789U (en) | Full-automatic liquid moving instrument | |
| CN108483385A (en) | A kind of extraction system | |
| CN108534817A (en) | Grating encoder reliability test | |
| CN218674492U (en) | Cable scrape abrasion resistance test device with double-guide bearing | |
| CN109706058A (en) | Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method | |
| CN209125470U (en) | A kind of micro- brill cylindrical grinding equipment | |
| CN115575591A (en) | Automatic detection system and method for chemical oxygen demand | |
| CN213854614U (en) | Detection apparatus for medical kit mould |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1198962 Country of ref document: HK |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20181128 Address after: 213000 Block B1, No. 9 Changyang Road, Changzhou West Taihu Science and Technology Industrial Park, Wujin District, Changzhou City, Jiangsu Province Patentee after: CHANGZHOU GENMAG BIOTECHNOLOGY CO., LTD. Address before: 100176 Fourth Floor 419, Block A, 18 West Ring South Road, Daxing District, Beijing Patentee before: BEIJING ZIYOUDU SCIENCE MACHINERY CO., LTD. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160831 Termination date: 20210320 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |