CN103830413A - Medicine used for treating dyspepsia, and preparation method thereof - Google Patents

Medicine used for treating dyspepsia, and preparation method thereof Download PDF

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Publication number
CN103830413A
CN103830413A CN201210474192.0A CN201210474192A CN103830413A CN 103830413 A CN103830413 A CN 103830413A CN 201210474192 A CN201210474192 A CN 201210474192A CN 103830413 A CN103830413 A CN 103830413A
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medicine
preparation
dyspeptic
prepared
parts
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CN201210474192.0A
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沈锋艳
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Abstract

The invention discloses a medicine used for treating dyspepsia, and a preparation method thereof. The medicine is mainly made from hawthorn, rhizoma atractylodis macrocephalae, radix aucklandiae, and herba houttuyniae; is capable of invigorating spleen and promoting digestion; possesses exact curative effects on dyspepsia; is safe and convenient; possesses no toxic or side effect; is convenient for consumption and carrying; and is easy for patients to accept.

Description

Treat dyspeptic medicine and preparation method thereof
Invention field:
The present invention relates to one and treat dyspeptic medicine and preparation method thereof, belong to the field of medicine technology.
Technical background:
Insufficiency of the spleen food stagnation, dyspepsia are a kind of common, multiple gastroenteropathys.People need to obtain needed various nutrition and energy by diet, digestion, absorption every day, safeguard self health.The food that normal person's moisture content is many just can digest and be over about 2 hour, the greasy food with hard just can digest and be over for general about 4 hours, the chances are 4 hours for the emptying time of stomach, if but gastric motility disorder, food can not normal stool, not only make patient produce upper abdominal pain, the symptom such as full, abdominal distention, belch early, more can make patient's malnutrition, affect patient's physical and mental health.Dyspepsia is mainly divided into functional dyspepsia and Organic dyspepsia.Cause that dyspeptic reason is a lot, comprise the chronic inflammatory disease at harmonization of the stomach duodenum position, make the normal creepage of gastrointestinal functions functional disorder of esophagus, Stomach duodenum.Patient's spirit unhappiness, long-term depressed or be subject to suddenly fierce stimulation etc. and all can cause.Gastroparesis is by due to diabetes, constitutional anorexia nervosa and gastrectomy.The cause of disease of functional dyspepsia and pathogenesis are still not exclusively clear, most scholars think that this disease is due to many factors, now generally acknowledged that its main pathogenesis is that gastrointestinal motility obstacle, gastric acid secretion are abnormal, internal organs perception allergy, and the effect of psychologic factors, dietary factor, helicobacter pylori infections and gut hormone etc. is still in exploration.The selection of functional dyspepsia Therapeutic Method is experimental, and there is no a kind of method or medicine has sure curative effect to all patients, also lacks objective reliable curative effect determinate standard.Doctor trained in Western medicine generally adopts and promotes the problems such as symptomatic treatment is carried out in the measure such as nurse of digestive tract power, gastric acid inhibitory, protection gastric mucosa, anti-helicobacter pylori, antidepressant and psychology, and effect is not ideal enough, and exists cost higher, and side effect is obvious.Chinese traditional treatment dyspepsia has obtained certain effect, the traditional Chinese medical science thinks that its disease is at stomach, relate to liver spleen, pathogenesis is mainly weakness of the spleen and stomach, disorder of QI movement, stomach-QI being unable to descend normally, so in the time for the treatment of functional dyspepsia, note invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, must rise temper, and gastric qi must be fallen, irritability must be relaxed, and disease must be controlled.Although scholars have carried out a large amount of research to dyspeptic treatment, but still lack at present determined curative effect, medicine or therapy that toxic and side effects is little, therefore, a kind of determined curative effect, toxic and side effects are little, and product that can quick solution dyspepsia problem be patient in the urgent need to.
Summary of the invention:
Technical problem to be solved by this invention is to provide one to treat dyspeptic medicine and preparation method thereof.Described medicine has effect of strengthening the spleen to promote digestion, has definite curative effect for treatment dyspepsia.
For solving above technical problem, the present invention by the following technical solutions:
One is treated dyspeptic medicine, and described medicine calculates according to composition by weight, is prepared from by Fructus Crataegi 10-20 part, Rhizoma Atractylodis Macrocephalae 2-10 part, Radix Aucklandiae 2-10 part, Herba Houttuyniae 2-10 part and adjuvant.
The dyspeptic medicine of aforementioned therapies, calculates according to composition by weight, is prepared from by 12 parts of Fructus Crataegis, 6 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of the Radix Aucklandiae, 6 parts of Herba Houttuyniae and adjuvant.
The preparation method of the dyspeptic medicine of aforementioned therapies is: by the prescription side of taking Chinese medicine, add conventional adjuvant, be prepared into conventional medicine preparation according to conventional method.
Described pharmaceutical preparation is capsule.
Described capsule is prepared like this: above-mentioned 4 taste medicines, and beat powder and cross 80 mesh sieves, soak 3 hours, decoct 2 times, each 1 hour, add for the first time 8 times of water gagings, add for the second time 6 times of water gagings, filter merging filtrate, get the filtrate thick paste that relative density is 1.35~1.38 while being concentrated into 80 DEG C ,-0.08Mpa, 70 DEG C of drying under reduced pressure, pulverized 40 mesh sieves, add the starch of the amount of making 10%, mix, incapsulate, to obtain final product.
The present invention is made up of Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae and Herba Houttuyniae.Wherein, Fructus Crataegi is the dry mature fruit of rosaceous plant Fructus Crataegi, Fructus Pyri Pashiae and Crataegi cuneatae; slightly warm in nature, sour in the mouth, sweet; there is promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, change the functions such as turbid blood fat reducing; for meat stagnation, epigastric distending pain, dysentery stomachache etc.; in Fructus Crataegi, contain the various active compositions such as ursolic acid, flavonoid, saponin, saccharide, organic acid, pigment, modern study proves that Fructus Crataegi has the effects such as protection brain, heart, liver, enhancing immunity, antitumor.The Rhizoma Atractylodis Macrocephalae is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae, warm in nature, sweet in the mouth, hardship, there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, for insufficiency of the spleen lack of appetite, phlegm retention vertigo and palpitation, spontaneous perspiration etc., in the Rhizoma Atractylodis Macrocephalae, contain volatile ingredient, lactone composition, glycoside, polysaccharide composition and aminoacid etc., modern study proves that the lactone material in the Rhizoma Atractylodis Macrocephalae has the function of invigorating the spleen and benefiting QI, adjusting gastrointestinal motility.The Radix Aucklandiae is the dry root of the feverfew Radix Aucklandiae, warm in nature, acrid in the mouth, hardship, there are promoting the circulation of QI to relieve pain, the effects such as strengthening the spleen to promote digestion, for heavy after the breast side of body, abdominal distention, dysentery, food stagnation does not disappear, anorexia etc., in the Radix Aucklandiae, contain terpenoid, alkaloid, anthraquinone, flavone etc., modern study proves that the Radix Aucklandiae has the merit of function of gallbladder promoting, stomach motility enhancing, anti-gastric-ulcer.Herba Houttuyniae be the fresh herb of saururaceae plant houttuynia cordata or dry aerial parts it.Cold in nature, acrid in the mouth, there is effect of heat-clearing and toxic substances removing, swollen clearly evacuation of pus, inducing diuresis for treating stranguria syndrome, be mainly used in that swollen carbuncle is suppurated, expectorant dyspnea of heat type is coughed, hematodiarrhoea pyretic stranguria, carbuncle sore tumefacting virus etc., Herba Houttuyniae contains Multiple components, as volatile oil, afzelin, hyperin and cordarine etc., modern study proves that Herba Houttuyniae has the effects such as antibacterial, antiviral, antiinflammatory, enhancing immunity.
The present invention is said medicine prescription, in side taking Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Radix Aucklandiae invigorating the spleen and benefiting QI, help digestion etc. as main body, the merit of Herba Houttuyniae heat-clearing and toxic substances removing in addition, all medicines are aided each other, play altogether effect of strengthening the spleen to promote digestion, have definite curative effect for treatment dyspepsia.
Clinical brief summary of the present invention is as follows:
1, clinical data: Cure for insomnia 80 examples, male 45 examples in 80 examples, female's 35 examples.The oldest 35-73 year, average 46.5 years old, average 4.0 months of the course of disease.
2, clinical symptoms---show as upper abdominal pain, early full, abdominal distention, belch, diarrhoea, constipation etc., many patients are simultaneously with insomnia, anxiety, depression, headache, the mental symptom such as absent minded.
3, Therapeutic Method: every day 3 times, each 2-3 grain, 1 week is 1 course for the treatment of.
4, therapeutic effect: in 80 examples, recovery from illness 27 examples, effective 35 examples, effective 11 examples, invalid 7 examples.
5,---clinical symptoms disappears completely, effective and effective---clinical symptoms has clear improvement, invalid---, and clinical symptoms has no improvement to treatment standard: recovery from illness.
6, total effective rate is: 91%.
Compared with the prior art, that medicine of the present invention has is evident in efficacy, result of use good, safe ready, the feature having no side effect, and take, carry more convenient, reach goal of the invention.
Further illustrate by the following examples the present invention, but not as limitation of the present invention.
Detailed description of the invention:
Embodiment 1
Prescription: Fructus Crataegi 12g, Rhizoma Atractylodis Macrocephalae 6g, Radix Aucklandiae 6g, Herba Houttuyniae 6g.
Technique: above-mentioned 4 taste medicines, beat powder and cross 80 mesh sieves, soak 3 hours, decoct 2 times, each 1 hour, add for the first time 8 times of water gagings, add for the second time 6 times of water gagings, filter merging filtrate, get the filtrate thick paste that relative density is 1.35~1.38 while being concentrated into 80 DEG C ,-0.08Mpa, 70 DEG C of drying under reduced pressure, pulverized 40 mesh sieves, add the starch of the amount of making 10%, mix, incapsulate, to obtain final product.
Usage and dosage: oral, every day 3 times, each 2-3 grain.

Claims (5)

1. the dyspeptic medicine for the treatment of, is characterized in that: described medicine calculates according to composition by weight, is prepared from by Fructus Crataegi 10-20 part, Rhizoma Atractylodis Macrocephalae 2-10 part, Radix Aucklandiae 2-10 part, Herba Houttuyniae 2-10 part and adjuvant.
2. treat as claimed in claim 1 dyspeptic medicine, it is characterized in that: described medicine calculates according to composition by weight, be prepared from by 12 parts of Fructus Crataegis, 6 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of the Radix Aucklandiae, 6 parts of Herba Houttuyniae and adjuvant.
3. the preparation method for the treatment of as claimed in claim 1 or 2 dyspeptic medicine, is characterized in that: by the prescription side of taking Chinese medicine, add conventional adjuvant, be prepared into conventional medicine preparation according to conventional method.
4. the preparation method for the treatment of as claimed in claim 3 dyspeptic medicine, is characterized in that: described pharmaceutical preparation is capsule.
5. treat as claimed in claim 4 the preparation method of dyspeptic medicine, it is characterized in that: described capsule is prepared like this: above-mentioned 4 taste medicines, beat powder and cross 80 mesh sieves, soak 3 hours, decoct 2 times, each 1 hour, add for the first time 8 times of water gagings, add for the second time 6 times of water gagings, filter, merging filtrate, gets the filtrate thick paste that relative density is 1.35~1.38 while being concentrated into 80 DEG C,-0.08Mpa, 70 DEG C of drying under reduced pressure, pulverized 40 mesh sieves, added the starch of the amount of making 10%, mixed, incapsulate, to obtain final product.
CN201210474192.0A 2012-11-20 2012-11-20 Medicine used for treating dyspepsia, and preparation method thereof Pending CN103830413A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643570A (en) * 2020-06-08 2020-09-11 石家庄市金元康牧药业有限公司 Pharmaceutical composition for treating proventriculitis of poultry and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008015430U1 (en) * 2008-11-20 2009-12-24 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Composition for the treatment of indigestion
CN102166267A (en) * 2011-04-22 2011-08-31 常洋 Traditional Chinese medicine composition used for improving appetite and promoting digestion and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008015430U1 (en) * 2008-11-20 2009-12-24 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Composition for the treatment of indigestion
CN102166267A (en) * 2011-04-22 2011-08-31 常洋 Traditional Chinese medicine composition used for improving appetite and promoting digestion and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643570A (en) * 2020-06-08 2020-09-11 石家庄市金元康牧药业有限公司 Pharmaceutical composition for treating proventriculitis of poultry and preparation method thereof

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Application publication date: 20140604

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