CN103816483A - Drug for treating middle-advanced stage esophagus cancer and preparation method thereof - Google Patents
Drug for treating middle-advanced stage esophagus cancer and preparation method thereof Download PDFInfo
- Publication number
- CN103816483A CN103816483A CN201410079854.3A CN201410079854A CN103816483A CN 103816483 A CN103816483 A CN 103816483A CN 201410079854 A CN201410079854 A CN 201410079854A CN 103816483 A CN103816483 A CN 103816483A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- rhizoma
- fructus
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a drug for treating middle-advanced stage esophagus cancer, which comprises the following components in parts by weight: 20-30 parts of codonopsis pilosula, 10-15 parts of rhizoma atractylodis macrocephalae, 10-15 parts of orange peel, 20-30 parts of semen coicis, 20-30 parts of Chinese yam, 5-10 parts of liquorice, 10-15 parts of mangnolia officinalis, 10-15 parts of fructus aurantii, 10-15 parts of radix curcumae, 5-10 parts of bulbus fritillariae cirrhosae, 10-15 parts of allium macrostemon, 10-15 parts of fructus trichosanthis, 20-30 parts of radix paeoniae alba, 10-15 parts of agilawood, 10-15 parts of fingered citron, 10-15 parts of arisaema consanguineum schott, 10-15 parts of radix scrophulariae, 10-15 parts of pericarpium citri reticulatae, 10-15 parts of pinellia ternate, 5-10 parts of fructus amomi, 10-15 parts of inula flower, 10-15 parts of ruddle, 10-15 parts of lotus petiole, 5-10 parts of coptis chinensis, 10-15 parts of radix aucklandiae, 10-15 parts of radix aucklandiae, 10-15 parts of adenophora stricta, 20-30 parts of rehmannia glutinosa, 10-20 parts of ophiopogon japonicas, 10-20 parts of angelica sinensis, 10-15 parts of lalang grass rhizome, 20-30 parts of oldenlandia diffusa, 20-30 parts of sculellaria barbata, 1-5 parts of centipede, 5-10 parts of buthus martensi kirsch, 10-20 parts of salvia miltiorrhiza, 10-15 parts of fructus forsythia, 10-20 parts of manyleaf paris rhizome, 10-15 parts of peach kernel, 10-15 parts of flos carthami, 10-15 parts of frankincense and 10-15 parts of myrrh. The drug can achieve the purposes of regulating qi-flowing and eliminating phlegm for removing stasis, nourishing yin and engendering liquid for removing stasis, and promoting blood circulation to remove blood stasis; the effective rate can reach 66%.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of the esophageal carcinoma, specifically, relate to a kind of medicine for the treatment of advanced esophageal carcinoma and preparation method thereof, belong to Chinese medicine technical field.
Background technology
The whole world approximately has 220,000 people to die from the esophageal carcinoma every year, China is Esophageal Cancer in High Risk Areas, because being only second to gastric cancer (accounting for 22.8%), death from esophageal carcinoma person (accounting for 22.4%) occupies second, age of onset is many more than 40 years old, men and women's PMR 1.3～2.7:1, but a 40 years old in recent years following patient has growth trend.The generation of the esophageal carcinoma and nitrosamine chronic stimulation, inflammation and wound, the micronutrient levels in inherited genetic factors and drinking-water, grain and vegetable is relevant.
The middle and advanced stage symptom main manifestations of the esophageal carcinoma can cause hoarseness for carrying out property acataposis, regurgitation of food, when cancerous protuberance compressing recurrent laryngeal nerve; Invade phrenic nerves and can cause singultus or diaphragmatic paralysis; When tumors invading and adjacent organs and while there is perforation, can there is esophagobronchial fistula, mediastinal abscess, pneumonia, pulmonary abscess and aorta and wear out massive hemorrhage and cause death.
Mainly contain palliative operation excision, local radiotherapy, chemotherapy, the combination of Chinese and Western medicine for the Therapeutic Method of advanced esophageal carcinoma clinically, wherein chemotherapy is one of primary treatment method of late esophagus cancer, but it exists the deficiencies such as poor selectivity, effective dose and toxic dose approach very much, toxic and side effects is serious, often makes patient be difficult to accept maybe can not adhere to the whole course for the treatment of.Radiotherapy also exists obvious side reaction, as radiation esophagitis, bring out tracheo esophageal fistula, bone marrow depression etc. and make many patients have to interrupt radiotherapy.
At present, also occurred clinically the Chinese medicine of multiple treatment advanced esophageal carcinoma, though obtained certain curative effect, effect is not ideal.
Summary of the invention
The technical problem to be solved in the present invention is for above deficiency, a kind of medicine for the treatment of advanced esophageal carcinoma is provided, has overcome the side effect of prior art Chinese medicine and western medicine larger, and the undesirable defect of effect, adopt described Drug therapy advanced esophageal carcinoma, therapeutic effect is obvious.Chemotherapy, radiotherapy side effect can be alleviated preferably, to increasing leukocytic quantity, strengthen immunologic function and all have good effect, and life in patients, extending life can be improved.
Another object of the present invention is to provide a kind of preparation method for the treatment of advanced esophageal carcinoma medicine.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: a kind of medicine for the treatment of advanced esophageal carcinoma, is characterized in that: the active ingredient of described medicine comprises by weight: Radix Codonopsis 20-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Pericarpium Citri tangerinae 10-15 part, Semen Coicis 20-30 part, Rhizoma Dioscoreae 20-30 part, Radix Glycyrrhizae 5-10 part, Cortex Magnoliae Officinalis 10-15 part, Fructus Aurantii 10-15 part, Radix Curcumae 10-15 part, Bulbus Fritillariae Cirrhosae 5-10 part, Bulbus Allii Macrostemonis 10-15 part, Fructus Trichosanthis 10-15 part, Radix Paeoniae Alba 20-30 part, Lignum Aquilariae Resinatum 10-15 part, Fructus Citri Sarcodactylis 10-15 part, Rhizoma Arisaematis 10-15 part, Radix Scrophulariae 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Rhizoma Pinelliae 10-15 part, Fructus Amomi 5-10 part, Flos Inulae 10-15 part, Haematitum 10-15 part, Petiolus nelumbinis 10-15 part, Rhizoma Coptidis 5-10 part, Radix Aucklandiae 10-15 part, Radix Pseudostellariae 10-15 part, Radix Adenophorae (Radix Glehniae) 10-15 part, Radix Rehmanniae 20-30 part, Radix Ophiopogonis 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Imperatae 10-15 part, Herba Hedyotidis Diffusae 20-30 part, Herba Scutellariae Barbatae 20-30 part, Scolopendra 1-5 part, Scorpio 5-10 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Forsythiae 10-15 part, Rhizoma Paridis 10-20 part, Semen Persicae 10-15 part, Flos Carthami 10-15 part, Olibanum 10-15 part and Myrrha 10-15 part.
A kind of prioritization scheme, the active ingredient of described medicine comprises by weight: Radix Codonopsis 15-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Pericarpium Citri tangerinae 15-20 part, Semen Coicis 15-25 part, Rhizoma Dioscoreae 15-25 part, Radix Glycyrrhizae 6-12 part, Cortex Magnoliae Officinalis 15-20 part, Fructus Aurantii 15-20 part, Radix Curcumae 15-20 part, Bulbus Fritillariae Cirrhosae 6-12 part, Bulbus Allii Macrostemonis 15-20 part, Fructus Trichosanthis 15-20 part, Radix Paeoniae Alba 15-25 part, Lignum Aquilariae Resinatum 15-20 part, Fructus Citri Sarcodactylis 15-20 part, Rhizoma Arisaematis 15-20 part, Radix Scrophulariae 15-20 part, Pericarpium Citri Reticulatae 15-20 part, Rhizoma Pinelliae 15-20 part, Fructus Amomi 6-12 part, Flos Inulae 15-20 part, Haematitum 15-20 part, Petiolus nelumbinis 15-20 part, Rhizoma Coptidis 6-12 part, Radix Aucklandiae 15-20 part, Radix Pseudostellariae 15-20 part, Radix Adenophorae (Radix Glehniae) 15-20 part, Radix Rehmanniae 15-25 part, Radix Ophiopogonis 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Imperatae 15-20 part, Herba Hedyotidis Diffusae 15-25 part, Herba Scutellariae Barbatae 15-25 part, Scolopendra 3-9 part, Scorpio 6-12 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Forsythiae 15-20 part, Rhizoma Paridis 10-20 part, Semen Persicae 15-20 part, Flos Carthami 15-20 part, Olibanum 15-20 part and Myrrha 15-20 part.
Further, the active ingredient of described medicine comprises by weight: 30 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Pericarpium Citri tangerinaes, 24 parts of Semen Coiciss, 24 parts of Rhizoma Dioscoreaes, 6 parts, Radix Glycyrrhizae, 10 parts of Cortex Magnoliae Officinalis, 13 parts of Fructus Aurantiis, 10 parts of Radix Curcumaes, 6 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Bulbus Allii Macrostemonis, 10 parts of Fructus Trichosanthis, 30 parts of the Radix Paeoniae Albas, 10 parts of Lignum Aquilariae Resinatum, 10 parts of Fructus Citri Sarcodactylis, 10 parts of Rhizoma Arisaematiss, 15 parts of Radix Scrophulariaes, 13 parts of Pericarpium Citri Reticulataes, 10 parts of the Rhizoma Pinelliaes, 6 parts of Fructus Amomis, 15 parts of Flos Inulae, 10 parts of Haematitums, 15 parts of Petiolus nelumbiniss, 10 parts of Rhizoma Coptidis, 10 parts of the Radix Aucklandiae, 15 parts of Radix Pseudostellariaes, 15 parts of Radix Adenophorae (Radix Glehniae), 24 parts, the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 20 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Imperataes, 30 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Scutellariae Barbataes, 6 parts of Scolopendras, 6 parts of Scorpios, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Forsythiaes, 20 parts of Rhizoma Paridis, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 10 parts of 10 parts of Olibanums and Myrrhas.
Based on described medicine, the preparation method of described medicine comprises the following steps:
A, take respectively each raw material according to weight portion;
B, Radix Aucklandiae (roasted): get undried Radix Aucklandiae sheet, in iron wire plaque, use one deck toilet paper, one deck Radix Aucklandiae sheet, several layers of interval tilings, put in the other or drying chamber of stove fire, dry to simmer to contained volatile oil in the Radix Aucklandiae to ooze to paper, take out, for subsequent use;
C, Olibanum (processed): get the Olibanum of choosing clean, put in pot and fry and slightly see melting point to surface with slow fire, be slightly yellow, taking-up cools; Or fry while dissolving to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, for subsequent use;
D, Myrrha (processed): get the Myrrha of choosing clean put pot in slow fire fry slightly see melting point to surface, taking-up cools; Or fry slightly see fusing during to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, for subsequent use;
E, Rhizoma Atractylodis Macrocephalae (parched): processed with honey wheat bran is sprinkled in heat pot, adds Rhizoma Atractylodis Macrocephalae sheet in the time smoldering, fry to coke yellow, effusion burnt odor gas, take out, sieve removes processed with honey wheat bran, for subsequent use;
F, Radix Paeoniae Alba (processed with vinegar): get Radix Paeoniae Alba sheet, mix thoroughly with rice vinegar, in slightly vexed rearmounted pot, by slow fire heating, fried dry, taking-up cools, for subsequent use;
G, Fructus Aurantii (parched): Fructus Aurantii is removed flesh, core, clean, and slightly soaks, and pulls out, softens, and can pinch doubling as degree take hands, and section, dries; Get wheat bran and be spread in heat pot, when the yellow skin of waiting is smoldered, add Fructus Aurantii sheet, fry to faint yellow, take out, sieve removes wheat bran, cools, for subsequent use;
H, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): get fresh ginger and squeeze out juice, residue adds clear water and repeatedly squeezes 2～3 times, for subsequent use after filtering; The Rhizoma Pinelliae and fresh ginger juice are mixed to exhaustion, added in the rearmounted cylinder of Alumen powder and salt down 3～4 days, then clear water is slowly poured in cylinder, continue to soak 3～4 days, take the slightly spicy sense of mouthfeel as degree, then pull out, wash most Alumen powder, dry in the air to sixty percent dry chip drying again, for subsequent use;
I, remaining raw material and Radix Aucklandiae (roasted), Olibanum (processed), Myrrha (processed), Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (processed with vinegar), Fructus Aurantii (parched), Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are mixed to get to the medicine for the treatment of advanced esophageal carcinoma.
Further, in step c, the weight ratio of Olibanum and rice vinegar is 50:3.
Further, in steps d, the weight ratio of Myrrha and rice vinegar is 50:3.
Further, in step e, the weight ratio of the Rhizoma Atractylodis Macrocephalae and processed with honey wheat bran is 10:1.
Further, in step f, the weight ratio of Radix Paeoniae Alba sheet and rice vinegar is 20:3.
Further, in step g, the weight ratio of Fructus Aurantii and wheat bran is 10:1.
Further, in step h, the weight ratio of the Rhizoma Pinelliae, Rhizoma Zingiberis Recens and Alumen is 20:5:3.
The pharmacology of above medicine is:
Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri tangerinae, Semen Coicis, Rhizoma Dioscoreae, Radix Glycyrrhizae have effect of reinforcing spleen and kidney, can improve immunity, enhancing body anti-cancer ability; Cortex Magnoliae Officinalis, Fructus Aurantii, Radix Curcumae, Bulbus Fritillariae Cirrhosae, Bulbus Allii Macrostemonis, Fructus Trichosanthis, the Radix Paeoniae Alba, Lignum Aquilariae Resinatum, Fructus Citri Sarcodactylis, Rhizoma Arisaematis, Radix Scrophulariae have effect of regulating the flow of QI to alleviate depression, dissipating phlegm and resolving masses, can be by activating QI to eliminate phlegm with antitumor; Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Fructus Amomi, Flos Inulae, Haematitum, Petiolus nelumbinis, Rhizoma Coptidis, the Radix Aucklandiae have effect of invigorating the spleen and regulating the stomach, stopping nausea and vomiting by lowering the adverse flow of QI, can appetite strengthening, alleviate chemotherapy, radiotherapy side effect; Radix Pseudostellariae, Radix Adenophorae (Radix Glehniae), the Radix Rehmanniae, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Imperatae have Yin-nourishing and body fluid promoting, effect of the eliminating stagnation that expels the heat-evil, can expel the heat-evil with antitumor by Yin-nourishing and body fluid promoting; Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Scolopendra, Scorpio, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Rhizoma Paridis, Semen Persicae, Flos Carthami, Olibanum, Myrrha have effect of heat-clearing and toxic substances removing, broken knot clots absorbing, can be by blood circulation promoting and blood stasis dispelling with antitumor.Make eventually it jointly reach resolving and invigoration therapies being applied simultaneously, blood stasis-eliminating and stagnation-dissipating and not hinder healthy energy, alleviate the object of chemotherapy, radiotherapy side effect simultaneously.
The present invention adopts above technical scheme, above interaction between component, advanced esophagus cancer patients is had to obvious blood stasis-eliminating and stagnation-dissipating effect, can reach the object of activating QI to eliminate phlegm eliminating stagnation, Yin-nourishing and body fluid promoting eliminating stagnation, blood circulation promoting and blood stasis dispelling eliminating stagnation simultaneously, chemotherapy, radiotherapy side effect be can alleviate preferably, to increasing leukocytic quantity, strengthen immunologic function and all have good effect, thereby quality of life of patients, extending life improved, through test, effective percentage can reach 66%.
Below in conjunction with the specific embodiment to technical scheme further instruction of the present invention.
The specific embodiment
Embodiment 1, a kind of medicine for the treatment of advanced esophageal carcinoma, the active ingredient of medicine comprises by weight: 15 parts of Radix Codonopsis, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Pericarpium Citri tangerinaes, 15 parts of Semen Coiciss, 25 parts of Rhizoma Dioscoreaes, 6 parts, Radix Glycyrrhizae, 15 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Aurantiis, 20 parts of Radix Curcumaes, 12 parts of Bulbus Fritillariae Cirrhosaes, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Fructus Trichosanthis, 15 parts of the Radix Paeoniae Albas, 20 parts of Lignum Aquilariae Resinatum, 20 parts of Fructus Citri Sarcodactylis, 20 parts of Rhizoma Arisaematiss, 15 parts of Radix Scrophulariaes, 15 parts of Pericarpium Citri Reticulataes, 20 parts of the Rhizoma Pinelliaes, 6 parts of Fructus Amomis, 15 parts of Flos Inulae, 15 parts of Haematitums, 15 parts of Petiolus nelumbiniss, 6 parts of Rhizoma Coptidis, 20 parts of the Radix Aucklandiae, 20 parts of Radix Pseudostellariaes, 20 parts of Radix Adenophorae (Radix Glehniae), 15 parts, the Radix Rehmanniae, 10 parts of Radix Ophiopogonis, 10 parts of Radix Angelicae Sinensis, 20 parts of Rhizoma Imperataes, 25 parts of Herba Hedyotidis Diffusaes, 25 parts of Herba Scutellariae Barbataes, 9 parts of Scolopendras, 6 parts of Scorpios, 10 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Forsythiaes, 10 parts of Rhizoma Paridis, 15 parts, Semen Persicae, 20 parts, Flos Carthami, 20 parts of Olibanums, 15 parts of Myrrhas.
Embodiment 2, a kind of medicine for the treatment of advanced esophageal carcinoma, the active ingredient of medicine comprises by weight: 25 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Pericarpium Citri tangerinaes, 25 parts of Semen Coiciss, 15 parts of Rhizoma Dioscoreaes, 12 parts, Radix Glycyrrhizae, 20 parts of Cortex Magnoliae Officinalis, 20 parts of Fructus Aurantiis, 15 parts of Radix Curcumaes, 6 parts of Bulbus Fritillariae Cirrhosaes, 20 parts of Bulbus Allii Macrostemonis, 20 parts of Fructus Trichosanthis, 25 parts of the Radix Paeoniae Albas, 15 parts of Lignum Aquilariae Resinatum, 15 parts of Fructus Citri Sarcodactylis, 15 parts of Rhizoma Arisaematiss, 20 parts of Radix Scrophulariaes, 20 parts of Pericarpium Citri Reticulataes, 15 parts of the Rhizoma Pinelliaes, 12 parts of Fructus Amomis, 20 parts of Flos Inulae, 20 parts of Haematitums, 20 parts of Petiolus nelumbiniss, 12 parts of Rhizoma Coptidis, 15 parts of the Radix Aucklandiae, 15 parts of Radix Pseudostellariaes, 15 parts of Radix Adenophorae (Radix Glehniae), 25 parts, the Radix Rehmanniae, 20 parts of Radix Ophiopogonis, 20 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Imperataes, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Herba Scutellariae Barbataes, 3 parts of Scolopendras, 12 parts of Scorpios, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Fructus Forsythiaes, 20 parts of Rhizoma Paridis, 15 parts, Semen Persicae, 15 parts, Flos Carthami, 15 parts of Olibanums, 20 parts of Myrrhas.
Embodiment 3, a kind of medicine for the treatment of advanced esophageal carcinoma, the active ingredient of medicine comprises by weight: 24 parts of Radix Codonopsis, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Pericarpium Citri tangerinaes, 15 parts of Semen Coiciss, 15 parts of Rhizoma Dioscoreaes, 4 parts, Radix Glycyrrhizae, 13 parts of Cortex Magnoliae Officinalis, 10 parts of Fructus Aurantiis, 13 parts of Radix Curcumaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 13 parts of Bulbus Allii Macrostemonis, 13 parts of Fructus Trichosanthis, 15 parts of the Radix Paeoniae Albas, 13 parts of Lignum Aquilariae Resinatum, 13 parts of Fructus Citri Sarcodactylis, 13 parts of Rhizoma Arisaematiss, 10 parts of Radix Scrophulariaes, 10 parts of Pericarpium Citri Reticulataes, 13 parts of the Rhizoma Pinelliaes, 4 parts of Fructus Amomis, 10 parts of Flos Inulae, 15 parts of Haematitums, 10 parts of Petiolus nelumbiniss, 13 parts of Rhizoma Coptidis, 13 parts of the Radix Aucklandiae, 10 parts of Radix Pseudostellariaes, 10 parts of Radix Adenophorae (Radix Glehniae), 20 parts, the Radix Rehmanniae, 10 parts of Radix Ophiopogonis, 15 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Imperataes, 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 3 parts of Scolopendras, 3 parts of Scorpios, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Forsythiaes, 15 parts of Rhizoma Paridis, 12 parts, Semen Persicae, 12 parts, Flos Carthami, 12 parts of Olibanums, 12 parts of Myrrhas.
Embodiment 4, a kind of medicine for the treatment of advanced esophageal carcinoma, the active ingredient of medicine comprises by weight: 30 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Pericarpium Citri tangerinaes, 24 parts of Semen Coiciss, 24 parts of Rhizoma Dioscoreaes, 6 parts, Radix Glycyrrhizae, 10 parts of Cortex Magnoliae Officinalis, 13 parts of Fructus Aurantiis, 10 parts of Radix Curcumaes, 6 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Bulbus Allii Macrostemonis, 10 parts of Fructus Trichosanthis, 30 parts of the Radix Paeoniae Albas, 10 parts of Lignum Aquilariae Resinatum, 10 parts of Fructus Citri Sarcodactylis, 10 parts of Rhizoma Arisaematiss, 15 parts of Radix Scrophulariaes, 13 parts of Pericarpium Citri Reticulataes, 10 parts of the Rhizoma Pinelliaes, 6 parts of Fructus Amomis, 15 parts of Flos Inulae, 10 parts of Haematitums, 15 parts of Petiolus nelumbiniss, 10 parts of Rhizoma Coptidis, 10 parts of the Radix Aucklandiae, 15 parts of Radix Pseudostellariaes, 15 parts of Radix Adenophorae (Radix Glehniae), 24 parts, the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 20 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Imperataes, 30 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Scutellariae Barbataes, 6 parts of Scolopendras, 6 parts of Scorpios, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Forsythiaes, 20 parts of Rhizoma Paridis, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 10 parts of Olibanums, 10 parts of Myrrhas.
Embodiment 5, a kind of medicine for the treatment of advanced esophageal carcinoma, the active ingredient of medicine comprises by weight: 20 parts of Radix Codonopsis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Pericarpium Citri tangerinaes, 20 parts of Semen Coiciss, 20 parts of Rhizoma Dioscoreaes, 8 parts, Radix Glycyrrhizae, 15 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Aurantiis, 15 parts of Radix Curcumaes, 8 parts of Bulbus Fritillariae Cirrhosaes, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Fructus Trichosanthis, 20 parts of the Radix Paeoniae Albas, 15 parts of Lignum Aquilariae Resinatum, 15 parts of Fructus Citri Sarcodactylis, 15 parts of Rhizoma Arisaematiss, 20 parts of Radix Scrophulariaes, 15 parts of Pericarpium Citri Reticulataes, 13 parts of the Rhizoma Pinelliaes, 8 parts of Fructus Amomis, 13 parts of Flos Inulae, 13 parts of Haematitums, 13 parts of Petiolus nelumbiniss, 15 parts of Rhizoma Coptidis, 15 parts of the Radix Aucklandiae, 18 parts of Radix Pseudostellariaes, 20 parts of Radix Adenophorae (Radix Glehniae), 18 parts, the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 24 parts of Radix Angelicae Sinensis, 20 parts of Rhizoma Imperataes, 25 parts of Herba Hedyotidis Diffusaes, 25 parts of Herba Scutellariae Barbataes, 8 parts of Scolopendras, 8 parts of Scorpios, 10 parts of Radix Salviae Miltiorrhizaes, 18 parts of Fructus Forsythiaes, 10 parts of Rhizoma Paridis, 15 parts, Semen Persicae, 15 parts, Flos Carthami, 15 parts of Olibanums, 15 parts of Myrrhas.
The medicine of above five embodiment is prepared according to following steps respectively:
A, take respectively each raw material according to weight portion;
B, Radix Aucklandiae (roasted): get undried Radix Aucklandiae sheet, in iron wire plaque, use one deck toilet paper, one deck Radix Aucklandiae sheet, several layers of interval tilings, put in the other or drying chamber of stove fire, dry to simmer to contained volatile oil in the Radix Aucklandiae to ooze to paper, take out;
C, Olibanum (processed): get the Olibanum of choosing clean, put in pot and fry and slightly see melting point to surface with slow fire, be slightly yellow, taking-up cools; Or fry while dissolving to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, (100 jin of every Olibanums, with 6 jin of rice vinegars);
D, Myrrha (processed): get the Myrrha of choosing clean put pot in slow fire fry slightly see melting point to surface, taking-up cools.Or fry slightly see fusing during to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, (every 100 jin of Myrrha, with 6 jin of rice vinegars);
E, Rhizoma Atractylodis Macrocephalae (parched): processed with honey wheat bran is sprinkled in heat pot, adds Rhizoma Atractylodis Macrocephalae sheet in the time smoldering, fry to coke yellow, effusion burnt odor gas, take out, sieve removes processed with honey wheat bran, (every 100 jin of the Rhizoma Atractylodis Macrocephalae, 10 jin, processed with honey wheat bran).
F, Radix Paeoniae Alba (processed with vinegar): get Radix Paeoniae Alba sheet, mix thoroughly with rice vinegar, in slightly vexed rearmounted pot, by slow fire heating, fried dry, taking-up cools, (every 100 jin of Radix Paeoniae Alba sheet, with 15 jin of rice vinegars).
G, Fructus Aurantii (parched): Fructus Aurantii is removed flesh, core, clean, and slightly soaks, and pulls out, softens, and can pinch doubling as degree take hands, and section, dries; Get wheat bran and be spread in heat pot, when the yellow skin of waiting is smoldered, add Fructus Aurantii sheet, fry to faint yellow, take out, sieve removes wheat bran, cools (every 100 jin of Fructus Aurantii, with 10 jin, wheat bran).
H, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): get fresh ginger and wash most silt, mash into mud shape, squeeze out juice, residue adds proper amount of clear water and repeatedly squeezes 2～3 times, for subsequent use after filtering.By Rhizoma Pinelliae size separately, choose decontamination, clean.Getting fresh ginger juice mixes to exhaustion; Add Alumen powder again, put in cylinder and salt down 3～4 days, clear water is slowly poured in cylinder, note Alumen powder not being poured to cylinder bottom, the water yield was advisable to soak 3～4 cun of the Rhizoma Pinelliaes.Continue to soak 3～4 days (not changing water), take a sample to check, take the slightly spicy sense of mouthfeel as degree; If any stronger numb taste, continue to soak; Then pull out, wash most Alumen powder, dry in the air to sixty percent dry chip drying again, for subsequent use; (every 100 jin of the Rhizoma Pinelliae, 20 jin, Rhizoma Zingiberis Recens, 15 jin of Alumens).
I, remaining raw material and Radix Aucklandiae (roasted), Olibanum (processed), Myrrha (processed), Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (processed with vinegar), Fructus Aurantii (parched), Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are mixed, must treat the medicine of advanced esophageal carcinoma.
The using method for the treatment of advanced esophageal carcinoma medicine is:
A, described raw material is placed in to marmite soaks decocting after 30-60 minute, change warm fire and continue to decoct 20-30 minute after boiling, medicine juice 150-200 milliliter removes slag to obtain;
Then medicinal residues are placed in again to marmite and soak decocting after 20 minutes, change warm fire and continue to decoct 20-30 minute after boiling, medicine juice 150-200 milliliter removes slag to obtain;
After being mixed, twice gained medicine juice must treat the medicine of advanced esophageal carcinoma.
B, a 150-200 milliliter, point early, late secondary, before the meal half an hour decoction being taken warmly.
Above five embodiment gained medicines are used for the treatment of to the test of advanced esophageal carcinoma, use efficacy assessment standard to be:
Effective: tumor disappears completely, esophagus the smooth of the edge, barium agent is by smooth, but tube wall can slightly show tetanic, and tube chamber is without narrow or slightly aobvious narrow, and mucosa substantially recovers normal or increases thick.
Take a turn for the better: pathological changes is most of to disappear, without significantly distortion or angulation, ulcer undirected chamber outside, barium agent is passed through still smooth, and it is smooth that edge is owed, and has little filling defect and/or little niche, though or edge smooth, but tube chamber has obvious stenosis.
Stablize or worsen: pathological changes has residual or do not see that pathological changes takes an evident turn for the better, and still has obvious filling defect and niche or narrow increasing the weight of.
The 180 routine advanced esophagus cancer patients that seek medical advice year October in July, 2009 to 2013, patient's disease meets " Internal Medicine-Oncology " the 3rd edition late esophagus cancer diagnostic criteria.180 examples are all esophageal squamous cell carcinoma through proved by pathology.Man's 67 examples, female's 113 examples, age 40-80 year, the course of disease 1 month to 3 years.
5 test group are set altogether, and each test group random assortment patient treats.Test group 1 is used radiotherapy or the chemotherapy Drug therapy of Application Example 1 gained simultaneously, test group 2 is used radiotherapy or the chemotherapy Drug therapy of Application Example 2 gained simultaneously, test group 3 is used radiotherapy or the chemotherapy Drug therapy of Application Example 3 gained simultaneously, test group 4 is used radiotherapy or the chemotherapy Drug therapy of Application Example 4 gained simultaneously, test group 5 is used radiotherapy or chemotherapy to apply the Drug therapy of the embodiment of the present invention 5 gained simultaneously, if 30 examples are matched group, matched group adopts the method treatment of chemotherapy or radiotherapy, total effective rate 50%.
The result that obtains of test is as following table:
Find out from above data, the medicine of the treatment advanced esophageal carcinoma that gained of the present invention adopts, total effective rate reaches more than 56.6%, and without obvious toxic-side effects, in above embodiment, embodiment 4 is preferred plan.
Unless stated otherwise, the degree relating to is mass percentage content.
Finally it should be noted that: the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a medicine for the treatment of advanced esophageal carcinoma, is characterized in that: the active ingredient of described medicine comprises by weight: Radix Codonopsis 20-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Pericarpium Citri tangerinae 10-15 part, Semen Coicis 20-30 part, Rhizoma Dioscoreae 20-30 part, Radix Glycyrrhizae 5-10 part, Cortex Magnoliae Officinalis 10-15 part, Fructus Aurantii 10-15 part, Radix Curcumae 10-15 part, Bulbus Fritillariae Cirrhosae 5-10 part, Bulbus Allii Macrostemonis 10-15 part, Fructus Trichosanthis 10-15 part, Radix Paeoniae Alba 20-30 part, Lignum Aquilariae Resinatum 10-15 part, Fructus Citri Sarcodactylis 10-15 part, Rhizoma Arisaematis 10-15 part, Radix Scrophulariae 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Rhizoma Pinelliae 10-15 part, Fructus Amomi 5-10 part, Flos Inulae 10-15 part, Haematitum 10-15 part, Petiolus nelumbinis 10-15 part, Rhizoma Coptidis 5-10 part, Radix Aucklandiae 10-15 part, Radix Pseudostellariae 10-15 part, Radix Adenophorae (Radix Glehniae) 10-15 part, Radix Rehmanniae 20-30 part, Radix Ophiopogonis 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Imperatae 10-15 part, Herba Hedyotidis Diffusae 20-30 part, Herba Scutellariae Barbatae 20-30 part, Scolopendra 1-5 part, Scorpio 5-10 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Forsythiae 10-15 part, Rhizoma Paridis 10-20 part, Semen Persicae 10-15 part, Flos Carthami 10-15 part, Olibanum 10-15 part and Myrrha 10-15 part.
2. a kind of medicine for the treatment of advanced esophageal carcinoma as claimed in claim 1, is characterized in that: the active ingredient of described medicine comprises by weight: Radix Codonopsis 15-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Pericarpium Citri tangerinae 15-20 part, Semen Coicis 15-25 part, Rhizoma Dioscoreae 15-25 part, Radix Glycyrrhizae 6-12 part, Cortex Magnoliae Officinalis 15-20 part, Fructus Aurantii 15-20 part, Radix Curcumae 15-20 part, Bulbus Fritillariae Cirrhosae 6-12 part, Bulbus Allii Macrostemonis 15-20 part, Fructus Trichosanthis 15-20 part, Radix Paeoniae Alba 15-25 part, Lignum Aquilariae Resinatum 15-20 part, Fructus Citri Sarcodactylis 15-20 part, Rhizoma Arisaematis 15-20 part, Radix Scrophulariae 15-20 part, Pericarpium Citri Reticulatae 15-20 part, Rhizoma Pinelliae 15-20 part, Fructus Amomi 6-12 part, Flos Inulae 15-20 part, Haematitum 15-20 part, Petiolus nelumbinis 15-20 part, Rhizoma Coptidis 6-12 part, Radix Aucklandiae 15-20 part, Radix Pseudostellariae 15-20 part, Radix Adenophorae (Radix Glehniae) 15-20 part, Radix Rehmanniae 15-25 part, Radix Ophiopogonis 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Imperatae 15-20 part, Herba Hedyotidis Diffusae 15-25 part, Herba Scutellariae Barbatae 15-25 part, Scolopendra 3-9 part, Scorpio 6-12 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Forsythiae 15-20 part, Rhizoma Paridis 10-20 part, Semen Persicae 15-20 part, Flos Carthami 15-20 part, Olibanum 15-20 part and Myrrha 15-20 part.
3. a kind of medicine for the treatment of advanced esophageal carcinoma as claimed in claim 1, it is characterized in that: the active ingredient of described medicine comprises by weight: 30 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Pericarpium Citri tangerinaes, 24 parts of Semen Coiciss, 24 parts of Rhizoma Dioscoreaes, 6 parts, Radix Glycyrrhizae, 10 parts of Cortex Magnoliae Officinalis, 13 parts of Fructus Aurantiis, 10 parts of Radix Curcumaes, 6 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Bulbus Allii Macrostemonis, 10 parts of Fructus Trichosanthis, 30 parts of the Radix Paeoniae Albas, 10 parts of Lignum Aquilariae Resinatum, 10 parts of Fructus Citri Sarcodactylis, 10 parts of Rhizoma Arisaematiss, 15 parts of Radix Scrophulariaes, 13 parts of Pericarpium Citri Reticulataes, 10 parts of the Rhizoma Pinelliaes, 6 parts of Fructus Amomis, 15 parts of Flos Inulae, 10 parts of Haematitums, 15 parts of Petiolus nelumbiniss, 10 parts of Rhizoma Coptidis, 10 parts of the Radix Aucklandiae, 15 parts of Radix Pseudostellariaes, 15 parts of Radix Adenophorae (Radix Glehniae), 24 parts, the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 20 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Imperataes, 30 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Scutellariae Barbataes, 6 parts of Scolopendras, 6 parts of Scorpios, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Forsythiaes, 20 parts of Rhizoma Paridis, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 10 parts of 10 parts of Olibanums and Myrrhas.
4. the preparation method of medicine as described in claim 1,2 or 3, is characterized in that: the preparation method of described medicine comprises the following steps:
A, take respectively each raw material according to weight portion;
B, Radix Aucklandiae (roasted): get undried Radix Aucklandiae sheet, in iron wire plaque, use one deck toilet paper, one deck Radix Aucklandiae sheet, several layers of interval tilings, put in the other or drying chamber of stove fire, dry to simmer to contained volatile oil in the Radix Aucklandiae to ooze to paper, take out, for subsequent use;
C, Olibanum (processed): get the Olibanum of choosing clean, put in pot and fry and slightly see melting point to surface with slow fire, be slightly yellow, taking-up cools; Or fry while dissolving to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, for subsequent use;
D, Myrrha (processed): get the Myrrha of choosing clean put pot in slow fire fry slightly see melting point to surface, taking-up cools;
Or fry slightly see fusing during to surface, spray rice vinegar, continue stir-fry saturating to outer bright light, taking-up cools, for subsequent use;
E, Rhizoma Atractylodis Macrocephalae (parched): processed with honey wheat bran is sprinkled in heat pot, adds Rhizoma Atractylodis Macrocephalae sheet in the time smoldering, fry to coke yellow, effusion burnt odor gas, take out, sieve removes processed with honey wheat bran, for subsequent use;
F, Radix Paeoniae Alba (processed with vinegar): get Radix Paeoniae Alba sheet, mix thoroughly with rice vinegar, in slightly vexed rearmounted pot, by slow fire heating, fried dry, taking-up cools, for subsequent use;
G, Fructus Aurantii (parched): Fructus Aurantii is removed flesh, core, clean, and slightly soaks, and pulls out, softens, and can pinch doubling as degree take hands, and section, dries; Get wheat bran and be spread in heat pot, when the yellow skin of waiting is smoldered, add Fructus Aurantii sheet, fry to faint yellow, take out, sieve removes wheat bran, cools, for subsequent use;
H, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens): get fresh ginger and squeeze out juice, residue adds clear water and repeatedly squeezes 2～3 times, for subsequent use after filtering; The Rhizoma Pinelliae and fresh ginger juice are mixed to exhaustion, added in the rearmounted cylinder of Alumen powder and salt down 3～4 days, then clear water is slowly poured in cylinder, continue to soak 3～4 days, take the slightly spicy sense of mouthfeel as degree, then pull out, wash most Alumen powder, dry in the air to sixty percent dry chip drying again, for subsequent use;
I, remaining raw material and Radix Aucklandiae (roasted), Olibanum (processed), Myrrha (processed), Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (processed with vinegar), Fructus Aurantii (parched), Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are mixed to get to the medicine for the treatment of advanced esophageal carcinoma.
5. the preparation method of medicine as claimed in claim 4, is characterized in that:
In step c, the weight ratio of Olibanum and rice vinegar is 50:3.
6. the preparation method of medicine as claimed in claim 4, is characterized in that:
In steps d, the weight ratio of Myrrha and rice vinegar is 50:3.
7. the preparation method of medicine as claimed in claim 4, is characterized in that:
In step e, the weight ratio of the Rhizoma Atractylodis Macrocephalae and processed with honey wheat bran is 10:1.
8. the preparation method of medicine as claimed in claim 4, is characterized in that:
In step f, the weight ratio of Radix Paeoniae Alba sheet and rice vinegar is 20:3.
9. the preparation method of medicine as claimed in claim 4, is characterized in that:
In step g, the weight ratio of Fructus Aurantii and wheat bran is 10:1.
10. the preparation method of medicine as claimed in claim 4, is characterized in that:
In step h, the weight ratio of the Rhizoma Pinelliae, Rhizoma Zingiberis Recens and Alumen is 20:5:3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410079854.3A CN103816483B (en) | 2014-03-06 | 2014-03-06 | A kind of medicine treating advanced esophageal carcinoma and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410079854.3A CN103816483B (en) | 2014-03-06 | 2014-03-06 | A kind of medicine treating advanced esophageal carcinoma and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103816483A true CN103816483A (en) | 2014-05-28 |
| CN103816483B CN103816483B (en) | 2016-08-24 |
Family
ID=50751963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410079854.3A Active CN103816483B (en) | 2014-03-06 | 2014-03-06 | A kind of medicine treating advanced esophageal carcinoma and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103816483B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189780A (en) * | 2014-09-23 | 2014-12-10 | 李玉富 | Traditional Chinese medicine for treating esophagus cancer |
| CN104489686A (en) * | 2015-01-08 | 2015-04-08 | 李宏 | Health herbal cuisine with synergism for chemotherapy and preparation of health herbal cuisine |
| CN104606581A (en) * | 2015-01-08 | 2015-05-13 | 李宏 | Traditional Chinese medicine diet for reducing side effects of chemotherapy and preparation method |
| CN109045267A (en) * | 2018-10-30 | 2018-12-21 | 冯光成 | It is a kind of for treating the Chinese prescription of cancer of the esophagus |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773659A (en) * | 2010-04-07 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating esophageal cancer and preparation method thereof |
| CN102940842A (en) * | 2012-10-01 | 2013-02-27 | 喻可安 | Anti-esophageal cancer drug |
| CN103520633A (en) * | 2013-09-06 | 2014-01-22 | 盛翔 | Processing method of anticancer blood-circulation activating and mass disintegrating ointment |
-
2014
- 2014-03-06 CN CN201410079854.3A patent/CN103816483B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773659A (en) * | 2010-04-07 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating esophageal cancer and preparation method thereof |
| CN102940842A (en) * | 2012-10-01 | 2013-02-27 | 喻可安 | Anti-esophageal cancer drug |
| CN103520633A (en) * | 2013-09-06 | 2014-01-22 | 盛翔 | Processing method of anticancer blood-circulation activating and mass disintegrating ointment |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189780A (en) * | 2014-09-23 | 2014-12-10 | 李玉富 | Traditional Chinese medicine for treating esophagus cancer |
| CN104489686A (en) * | 2015-01-08 | 2015-04-08 | 李宏 | Health herbal cuisine with synergism for chemotherapy and preparation of health herbal cuisine |
| CN104606581A (en) * | 2015-01-08 | 2015-05-13 | 李宏 | Traditional Chinese medicine diet for reducing side effects of chemotherapy and preparation method |
| CN109045267A (en) * | 2018-10-30 | 2018-12-21 | 冯光成 | It is a kind of for treating the Chinese prescription of cancer of the esophagus |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103816483B (en) | 2016-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102847064B (en) | Chinese herbal medicine used for inhibition of malignant tumor metastasis | |
| CN103768398B (en) | Traditional Chinese medicine composition for treating advanced lung tumors | |
| CN103816483B (en) | A kind of medicine treating advanced esophageal carcinoma and preparation method thereof | |
| CN104771707A (en) | Traditional Chinese medicine composition for treating chronic gastritis | |
| CN103536852A (en) | Pharmaceutical composition for treating mental disease and use thereof | |
| CN103768542A (en) | Medicine for treating ascites due to liver cancer and preparation method thereof | |
| CN104523873A (en) | Pharmaceutical composition for treating gout | |
| CN104107408A (en) | Traditional Chinese medicinal composition for treating gastric diseases | |
| CN1730089A (en) | Chinese traditional medicine with hemorrhoid resolving, poison expelling and stagnation expelling functions | |
| CN106266972A (en) | A kind of Chinese medicine formula treating pulmonary carcinoma | |
| CN104771706A (en) | Traditional Chinese medicine composition for treating chronic urticaria | |
| CN104758676A (en) | Medicine for treating damp-heat in resistance-type epigastric pain | |
| CN104623544A (en) | Traditional Chinese medicine preparation capable of tonifying spleen and eliminating dampness for treating moderate fatty liver and preparation method of traditional Chinese medicine preparation | |
| CN107714905A (en) | A kind of Chinese medicine composition of clearing heat and removing internal heat | |
| CN105663551A (en) | Traditional Chinese medicine preparation for patient suffering from pancreatic cancer to take after operation as well as preparation method | |
| CN101172156A (en) | Traditional Chinese medicine for treating enteron tumour and method for preparing the same | |
| CN104998212A (en) | Medicament for treating cervical cancer and preparation method thereof | |
| CN1879824A (en) | A medicinal liquor for treating damp-heat accumulation type liver cirrhosis and method for preparing same | |
| CN105521223A (en) | Traditional Chinese medicinal preparation for realizing adjuvant therapy on pancreatic cancer and preparation method of traditional Chinese medicinal preparation | |
| CN105617197A (en) | Traditional Chinese medicine composition for treating chronic renal failure of dogs as well as preparation method and application of traditional Chinese medicine composition | |
| CN104274781B (en) | It is a kind of to treat because of Chinese medicine preparation that liver cancer cause is off one's feed and preparation method thereof | |
| CN103272198A (en) | Traditional Chinese medicinal composition for treating radiographic vomit | |
| CN104644842A (en) | Preparation method of concentrated foot soaking liquid | |
| CN118286374A (en) | A medicinal ointment for treating qi deficiency and blood stasis, and its preparation method | |
| CN115779023A (en) | Traditional Chinese medicine composition for treating stomachache and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Yingli Inventor after: Lv Yanli Inventor before: Wang Yingli Inventor before: Sun Yu |
|
| COR | Change of bibliographic data | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |