CN103800874B - A kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance - Google Patents

A kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance Download PDF

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Publication number
CN103800874B
CN103800874B CN201410018966.8A CN201410018966A CN103800874B CN 103800874 B CN103800874 B CN 103800874B CN 201410018966 A CN201410018966 A CN 201410018966A CN 103800874 B CN103800874 B CN 103800874B
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China
Prior art keywords
pharmaceutical composition
fumigation treatment
parts
treatment apoplexy
apoplexy hemiplegia
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CN201410018966.8A
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Chinese (zh)
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CN103800874A (en
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李江
张茹
张云
许晓燕
胡春楠
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Affiliated Hospital of Medical College Qingdao University
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Affiliated Hospital of Medical College Qingdao University
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Abstract

The invention discloses a kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance, said composition is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 25-35 part, Flos Sophorae 25-35 part, Rhizoma Zingiberis 13-20 part, Spina Gleditsiae 13-20 part, Folium Artemisiae Argyi 13-20 part, Rhizoma Acori Graminei 6-10 part, Folium Mori 25-35 part, Pericarpium Citri Reticulatae Viride 25-35 part.Pharmaceutical composition of the present invention effective ingredient stripping after decocting forms medicine steam, during fumigation treatment, these active substance infiltrate suffering limb periarticular tissue by skin, can reach rapidly and eliminate limbs pain swelling, relieve muscle spasms, thus reach therapeutic purposes.

Description

A kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance
Technical field
The invention belongs to medical art, in particular to a kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance.
Background technology
Apoplexy disease is the disease that disability rate is the highest now, and Post stroke leaves over limbs disturbance, has become day by day serious social problem.Post stroke hemiplegia about has patient's existence spasm to a certain degree of 80% ~ 90%.In the process that hemiplegia is recovered, removing spasm is one of key problem, and how effectively suppressing spasm, bring out proper motion pattern, is the problem that current many scholars are inquiring into.Conventional western medicine untoward reaction is more, and long-term effect has to be determined, and surgery carries out that selectivity neureotomy treatment difficulty is large, technical requirement is high, costly, not easily promoted.
Summary of the invention
The object of the present invention is to provide a kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance.Said composition, as secret prescription handed down in the family from generation to generation, has good effect, advantage that recurrence rate after healing is low, determines that it is a kind of specific medicament for the treatment of apoplexy hemiplegia limbs disturbance after many decades clinical practice.
The object of the present invention is achieved like this:
A kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance, by weight, described pharmaceutical composition is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 25-35 part, Flos Sophorae 25-35 part, Rhizoma Zingiberis 13-20 part, Spina Gleditsiae 13-20 part, Folium Artemisiae Argyi 13-20 part, Rhizoma Acori Graminei 6-10 part, Folium Mori 25-35 part, Pericarpium Citri Reticulatae Viride 25-35 part.
Preferably, the pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance described above, by weight, it is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 28-32 part, Flos Sophorae 28-32 part, Rhizoma Zingiberis 15-18 part, Spina Gleditsiae 15-18 part, Folium Artemisiae Argyi 15-18 part, Rhizoma Acori Graminei 7-9 part, Folium Mori 28-32 part, Pericarpium Citri Reticulatae Viride 28-32 part.
In a most preferred embodiment of the present invention, the pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance described above, by weight, it is prepared from by the Chinese crude drug of following consumption: by Fructus Arctii 30 parts, 30 parts, Flos Sophorae, Rhizoma Zingiberis 16 parts, Spina Gleditsiae 16 parts, Folium Artemisiae Argyi 16 parts, Rhizoma Acori Graminei 8 parts, 30 parts, Folium Mori, 30 parts, Pericarpium Citri Reticulatae Viride.
Further preferably, the pharmaceutical composition of described fumigation treatment apoplexy hemiplegia limbs disturbance is powder.
The preparation method of the Chinese medicine preparation of fumigation treatment apoplexy hemiplegia limbs disturbance of the present invention comprises the steps: to take Fructus Arctii, Flos Sophorae, Rhizoma Zingiberis, Spina Gleditsiae, Folium Artemisiae Argyi, Rhizoma Acori Graminei, Folium Mori and Pericarpium Citri Reticulatae Viride by prescription, pulverizes after mixing, packaging.
According to Chinese medicine Historical Data Data About, pharmacologically active and the source of above-mentioned Chinese crude drug are as follows:
Fructus Arctii: the effect with dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling, cure mainly cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule not thoroughly, rubella pruritus, sore swollen toxin.Be selected from the dry mature fruit of feverfew Fructus Arctii ArctiumlappaL..
Flos Sophorae: cooling blood for hemostasis; Liver heat removing and eyesight improving.Main discharging fresh blood stool; Hemorrhoid hematochezia; Dysentery; Hematuria; Stranguria with blood; Metrorrhagia; Spit blood; Epistaxis; Liver-heat is had a headache; Conjunctival congestion and swelling pain; Carbuncle skin infection.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.
Rhizoma Zingiberis: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.Cure mainly coldness and pain in the epigastrium; Vomiting; Have loose bowels, YANG-depletion is fainted inverse; Cold fluid-retention is breathed with cough; Arthralgia due to cold-dampnes.Select the dry rhizome of zingiber ZingiberofficinaleRosc..
Spina Gleditsiae: invigorate blood circulation, dispels the wind.Be used for the treatment of swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.Select the dry Spina jujubae of leguminous plant Fructus Gleditsia GleditsiasinensisLam..
Folium Artemisiae Argyi: dispersing cold for relieving pain, warming the meridian for stopping bleeding.For few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spit blood, epistaxis, metrorrhagia through many, gestation hemorrhage; External treatment skin pruritus, decortication.Select the dried leaves of feverfew Chinese mugwort ArtemisiaargyiLevl.etVant..
Rhizoma Acori Graminei: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Derive from the rhizome of acorus gramineus araceae plant.
Folium Mori: there is dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, effect of cooling blood for hemostasis.Select the dried leaves of Moraceae Moraceae plant Mulberry MorusalbaL..
Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, removing food stagnancyization are stagnant.For costa sternales gastral cavity distending pain, acute mastitis, colic, stagnation of QI due to dyspepsia.Select the dry young fruit of rutaceae orange CitrusreticulataBlanco and variety thereof or the peel of immature fruit.
The pharmaceutical composition that the present invention relates to coordinates stifling, has medicine and the warm dual function of physics.Warm-heat effect can make Golgi tendon organ activation, suppresses gamma fiber activeness, thus makes that spasm is tetanic to be eased.The effective ingredient stripping after decocting of this prescription forms medicine steam, and during fumigation treatment, these active substance infiltrate suffering limb periarticular tissue by skin, can reach rapidly and eliminate limbs pain swelling, relieve muscle spasms, thus reach therapeutic purposes.Compare simple exercise therapy, the present invention adopts Chinese medicine fumigation can obviously improve stroke hemiplegia limbs disturbance, improves its motor function and functional independence.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Prescription: Fructus Arctii 3.0 kilograms, 3.0 kilograms, Flos Sophorae, Rhizoma Zingiberis 1.6 kilograms, Spina Gleditsiae 1.6 kilograms, Folium Artemisiae Argyi 1.6 kilograms, Rhizoma Acori Graminei 0.8 kilogram, 3.0 kilograms, Folium Mori, 3.0 kilograms, Pericarpium Citri Reticulatae Viride.
Preparation method: take Fructus Arctii, Flos Sophorae, Rhizoma Zingiberis, Spina Gleditsiae, Folium Artemisiae Argyi, Rhizoma Acori Graminei, Folium Mori and Pericarpium Citri Reticulatae Viride by prescription, pulverizes after mixing, by 200 grams every bag packagings.
Embodiment 2
Prescription: Fructus Arctii 3.5 kilograms, 3.5 kilograms, Flos Sophorae, Rhizoma Zingiberis 1.3 kilograms, Spina Gleditsiae 1.9 kilograms, Folium Artemisiae Argyi 1.8 kilograms, Rhizoma Acori Graminei 0.6 kilogram, 3.0 kilograms, Folium Mori, 2.8 kilograms, Pericarpium Citri Reticulatae Viride.
Preparation method: take Fructus Arctii, Flos Sophorae, Rhizoma Zingiberis, Spina Gleditsiae, Folium Artemisiae Argyi, Rhizoma Acori Graminei, Folium Mori and Pericarpium Citri Reticulatae Viride by prescription, pulverizes after mixing, by 200 grams every bag packagings.
Embodiment 3
Prescription: Fructus Arctii 2.6 kilograms, 3.5 kilograms, Flos Sophorae, Rhizoma Zingiberis 2.0 kilograms, Spina Gleditsiae 1.3 kilograms, Folium Artemisiae Argyi 1.6 kilograms, Rhizoma Acori Graminei 1.0 kilograms, 2.8 kilograms, Folium Mori, 3.2 kilograms, Pericarpium Citri Reticulatae Viride.
Preparation method: take Fructus Arctii, Flos Sophorae, Rhizoma Zingiberis, Spina Gleditsiae, Folium Artemisiae Argyi, Rhizoma Acori Graminei, Folium Mori and Pericarpium Citri Reticulatae Viride by prescription, pulverizes after mixing, by 200 grams every bag packagings.
Clinical practice example
Apoplexy hemiplegia spasm patient 38 example, make a definite diagnosis through CT or MRI, all there is hemiplegia and accompany upper limb biceps brachii m., lower limb quadriceps femoris muscular tension to raise, according to Ashworth grade scale, patient's muscular tension > 0 grade ,≤3 grades, vital signs stable, without obvious cognitive disorder, correctly can accept action command.Case exclusion standard: 1. previously have dyskinesia; 2. serious hypertension, coronary heart disease, pulmonary infection, renal dysfunction, severe diabetes is associated with; 3. severe mental disturbances; 4. dysnoesia; 5. have a delicate constitution; 6. malignant tumor.
All patients treat in herbal fumigation mode, concrete grammar is: Chinese powder medicine one prepared by Example 1 wraps, all medicines are soaked half an hour, then the special frying pan decoction generation Chinese medicine steam feeding treatment cabin that vapour treats instrument is put into, temperature adjustment in treatment cabin is reached 37 DEG C, patient is allowed to enter cabin, time 20min.Above-mentioned treatment every day 1 time 1 month is a course for the treatment of.
After a course of therapy terminates, upper limb is based on elbow joint, and lower limb are object of observation with knee joint, takes the criterion of therapeutical effect of judge spasm conventional in domestic clinical data.Effective: to reduce by 2 grades of muscular tension; Effective: to reduce by 1 grade of muscular tension; Take a turn for the better: reduce by half grade of muscular tension; Invalid: without improving.38 routine patients are result display after treatment: effective 15 examples of upper limb, effective 13 examples, and take a turn for the better 7 examples, invalid 3 examples, and total effective rate is 92.1%; Effective 17 examples of lower limb, effective 14 examples, take a turn for the better 6 examples, and invalid 1 example, total effective rate is 97.4%.Compare simple exercise therapy, the present invention adopts Chinese medicine fumigation can obviously improve stroke hemiplegia limb spasm, improves its motor function and functional independence.

Claims (4)

1. the pharmaceutical composition of a fumigation treatment apoplexy hemiplegia limbs disturbance, it is characterized in that: by weight, described pharmaceutical composition is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 25-35 part, Flos Sophorae 25-35 part, Rhizoma Zingiberis 13-20 part, Spina Gleditsiae 13-20 part, Folium Artemisiae Argyi 13-20 part, Rhizoma Acori Graminei 6-10 part, Folium Mori 25-35 part, Pericarpium Citri Reticulatae Viride 25-35 part.
2. the pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance according to claim 1, it is characterized in that: by weight, described pharmaceutical composition is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 28-32 part, Flos Sophorae 28-32 part, Rhizoma Zingiberis 15-18 part, Spina Gleditsiae 15-18 part, Folium Artemisiae Argyi 15-18 part, Rhizoma Acori Graminei 7-9 part, Folium Mori 28-32 part, Pericarpium Citri Reticulatae Viride 28-32 part.
3. the pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance according to claim 2, it is characterized in that: by weight, described pharmaceutical composition is prepared from by the Chinese crude drug of following consumption: Fructus Arctii 30 parts, 30 parts, Flos Sophorae, Rhizoma Zingiberis 16 parts, Spina Gleditsiae 16 parts, Folium Artemisiae Argyi 16 parts, Rhizoma Acori Graminei 8 parts, 30 parts, Folium Mori, 30 parts, Pericarpium Citri Reticulatae Viride.
4. the pharmaceutical composition of the fumigation treatment apoplexy hemiplegia limbs disturbance according to claim 1 or 2 or 3, is characterized in that: described pharmaceutical composition is powder.
CN201410018966.8A 2014-01-15 2014-01-15 A kind of pharmaceutical composition of fumigation treatment apoplexy hemiplegia limbs disturbance Expired - Fee Related CN103800874B (en)

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