CN103800447B - The antipyretic granule of fragrant a kind of reed mentioned in ancient books - Google Patents
The antipyretic granule of fragrant a kind of reed mentioned in ancient books Download PDFInfo
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- CN103800447B CN103800447B CN201310388089.9A CN201310388089A CN103800447B CN 103800447 B CN103800447 B CN 103800447B CN 201310388089 A CN201310388089 A CN 201310388089A CN 103800447 B CN103800447 B CN 103800447B
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Abstract
The antipyretic granule of a kind of fragrant a kind of reed mentioned in ancient books relates to a kind of pharmaceutical composition, particularly a kind of botanical medicine compositions of pure natural, and the present invention is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g.The present invention is directed to the Chinese patent medicine that there is not yet the heating for the treatment of summer-heat damp cold at present on the market, foundation for many years clinical empirical summary goes out to treat fragrant a kind of reed mentioned in ancient books soup of summer-heat damp cold heating, for avoiding the deficiency of decoction, the curative effect advantage of better performance former side's treatment summer-heat damp cold heating, this project adopts modern pharmaceutical technology, be determined curative effect by the transformation of the way of former side's decoction, take easy to carry, the good child of mouthfeel is happy to the antipyretic granule of fragrant a kind of reed mentioned in ancient books taken.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly a kind of botanical medicine compositions of pure natural.
Background technology
Flu is the acute respiratory disease of harm humans health, and each age group all can occur throughout the year, common with summer and autumn morbidity.Annual about 1 ~ 3 time of adult, child 2 ~ 7 times.Especially be common with summer-wet type common cold.Children's's the spleen tending to insufficiency usually, lungs are tender and lovely, summer and autumn, hot climate, and rainy humidity, more easily suffers from summer-heat damp cold.There is high heat during morbidity, performance that dizzy headache, extremities aching pain, vomiting sleepy, uncomfortable in chest, the heat-damp in summer such as uncomfortable of defecating are trouble.High heat not only can increase the weight of cardiopulmonary burden, and the infant high heat of less than 3 years old also may cause hyperpyrexia convulsion
［ 1 ］, therefore for this kind of flu infant, control with clearing away summer-heat heat, damp eliminating is evil, making body temperature be down to normal is fast the task of top priority.
Modern medicine is thought, causes the factor of upper respiratory tract infection, based on virus, accounts for primary infection more than 85%
［ 3 ］, in developing country, when virus causes upper respiratory tract infection, very easily merge bacteriological infection.Primary disease prevalence is high, in month occurred frequently, can reach 8% ~ 30%.Current upper respiratory tract infection western medical treatment mainly adopts general treatment, etiological treatment combines with symptomatic treatment, and antibiotic is only effective to antibacterial, invalid to virus.The drug resistance of antiviral drugs and serious side effects limit its application clinically, and therefore the treatment of viral influenza is the same with other viral diseases, does not also have specific Drug therapy.Simple antipyretic-antalgic is all not good to summer-heat damp cold (being similar to common cold of gastrointestinal type) curative effect, and heat is moved back and multiple liter often, and the touching difficulty of the course of disease more.Although developed now the vaccine of upper respiratory infection, because antigen constantly makes a variation, novel continuous generation, other strain of different shaped can be simultaneously popular in crowd, and therefore vaccine can only for certain several specific virus, and the scope of application is little.Interferon also can improve local respiratory tract immunity function, but has certain side effect, and expensive, not easily promotes the use of.
A large amount of research data confirms: treatment by Chinese herbs upper respiratory tract infection has unique advantage, can effective cure diseases, reduces antibiotic on the impact of probiotic bacteria while kill bacteria, adjustment systemic immune system, enhancing human body immunity power
［ 7 ］.But conventional dosage forms takes inconvenience, drug dose is large, is also not easily accepted by children's, has had a strong impact on the performance of important advantages.Therefore, develop taking convenience, new product of Chinese medicine that is safe and effective, treatment cold, fever has important medical value and realistic meaning.
Summary of the invention
Object of the present invention is intended to the defect overcoming prior art, provide a kind of be used for the treatment of summer-heat damp cold heating and determined curative effect, take easy to carry, the good child of mouthfeel is happy to the antipyretic granule of fragrant a kind of reed mentioned in ancient books taken.
The antipyretic granule of fragrant a kind of reed mentioned in ancient books of the present invention, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g.
The described antipyretic granule of fragrant a kind of reed mentioned in ancient books, plus-minus: head general pain folder is cold, adds Ramulus Cinnamomi, Radix Puerariae; Head general pain very, adds the Radix Angelicae Dahuricae, Rhizoma Et Radix Notopterygii; Cough adds Radix Peucedani, Rhizoma Cynanchi Stauntonii; Nausea and vomiting adds Rhizoma Pinelliae Preparata; Dyspepsia adds Massa Medicata Fermentata; Body of the tongue thick fur is greasy adds Semen Raphani.
The described antipyretic granule of fragrant a kind of reed mentioned in ancient books, Radix Bupleuri, Herba Pogostemonis, Fructus Forsythiae steam reflux, extract, volatile oil, remaining medicinal residues and all the other four Chinese medicines decoct jointly makes dried cream powder end, then is prepared from inclusion essential oil.The ratio of volatile oil/beta-schardinger dextrin-is 1:8-12, and enclose temperature is 30-50 DEG C, and the enclose time is 40-80min.
The described antipyretic granule of fragrant a kind of reed mentioned in ancient books, can also be prepared as the dosage form such as oral liquid, ball, loose, drop pill, capsule according to actual needs.
In the present invention, Herba Pogostemonis, Radix Bupleuri are monarch drug.Radix Bupleuri bitter in the mouth is pungent, cold nature, deliver and in, yang invigorating of bringing down a fever; Herba Pogostemonis acrid in the mouth, slightly warm in nature, eliminating turbid pathogen with aromatics, deliver expelling summer-heat, the two compatibility tool relieving the exterior syndrome is brought down a fever the merit of removing dampness, makes the heresy of heat-damp in summer thoroughly reach hinge and separates in flesh table; The special lung heat clearing sthenia gastropyrexia of Gypsum Fibrosum, damp and hot in the clear eliminating the pathogens from the lung of Radix Scutellariae, Fructus Forsythiae, Folium Isatidis heat-clearing and toxic substances removing; Herba Artemisiae Annuae has heat-clearing and toxic substances removing, removes the effects such as steaming, preventing the attack (or recurrence) of malaria is ministerial drug.All medicines share, the merit of expelling pathogenic factors from the exterior heat clearing away, dispelling phlegm and relieving sore-throat, the removing dampness that helps digestion.Its function cures mainly: expelling pathogenic factors from the exterior heat clearing away, dispelling phlegm and relieving sore-throat, help digestion removing dampness.Heating, pharyngalgia, cough, greasy fur etc. are seen for summer-heat damp cold card.
The present invention is directed to the Chinese patent medicine that there is not yet the heating for the treatment of summer-heat damp cold at present on the market, foundation for many years clinical empirical summary goes out to treat fragrant a kind of reed mentioned in ancient books soup of summer-heat damp cold heating, for avoiding the deficiency of decoction, the curative effect advantage of better performance former side's treatment summer-heat damp cold heating, this project adopts modern pharmaceutical technology, be determined curative effect by the transformation of the way of former side's decoction, take easy to carry, the good child of mouthfeel is happy to the antipyretic granule of fragrant a kind of reed mentioned in ancient books taken.
Clinical effectiveness of the present invention:
One, patient data
Compile in October, the 2008 ~ 2011 year routine case of out-patient department of Yunnan University of Traditional Chinese Medicine 120 in October, wherein man 65 example, female 55 example; 0.5 ~ 4 years old 46 age example; 5 ~ 12 years old 40 examples; >=13 years old 34 examples.The course of disease 1 ~ 3 day, disease sees heating, and body temperature is at 38 DEG C ~ 41 DEG C, and within 24 hours, body temperature fluctuation is no more than 1C, no relieving of symptom after perspiration, and asthenia drowsiness is uncomfortable in chest, nausea and vomiting, indigestion and loss of appetite, yellowish urine, and the dizzy nose heave acroesthesia of Annual wool yield private prosecution, red tongue yellow and greasy fur, soft and rapid pulse, fingerprint purple is stagnant.Be divided into matched group and treatment group at random, often organize 60 examples, two groups of data there was no significant differences.
Two, Therapeutic Method
Matched group oral bavin osmanthus granule, every day three times, 0.5 ~ 1 years old each 1/4 bag; 2 ~ 4 years old each 1/3 bag, 5 ~ 10 years old each 1/2 bag; >=11 years old each 1 bag, the antipyretic soup decoction of the fragrant a kind of reed mentioned in ancient books for the treatment of group, every day three times, a 20 ~ 100ml; Herba Pogostemonis lOg, Radix Scutellariae 6 ~ lOg; Fructus Forsythiae 5 ~ lOg, Herba Artemisiae Annuae 5 ~ lOg, Folium Isatidis 5 ~ lOg, Gypsum Fibrosum 10 ~ 20g; Radix Bupleuri 5 ~ lOg.
Three, Fang Yi analyzes
The purport of fragrant a kind of reed mentioned in ancient books antipyretic granule honor YE Tian shi " dissipating the wind outward to separate it from the heat, eliminating dampness by diuresis to separate it from pathogenic heat ", clear a surname, thinization, expelling pathogenic factors from the exterior, all methods of removing toxic substances executing, with Herba Pogostemonis, Radix Scutellariae for monarch.Herba Pogostemonis acrid in the mouth, slightly warm in nature, the flesh natural fibre line of meat, thoroughly hair key can be opened, separate pathogenic summer-heat, fast taste, removing dampness are turbid, ward off dirty evil; Radix Scutellariae bitter in the mouth is cold in nature, clearing away heat-fire dampness, the merit of the two compatibility tool expelling pathogenic factors from the exterior clearing away heat and eliminating dampness.Herba Artemisiae Annuae bitter in the mouth gas is cold and fragrant, and hardship can expel the heat-evil, and coldly can bring down a fever, and especially can rush down the fire of summer-heat, fragrance enters spleen, does not violate gastric qi with it; Folium Isatidis both clearing heat in QI system divides excess-heat, separates noxious heat in the blood system again; Gypsum Fibrosum clearing away lung-heat, rush down stomach-fire, except damp and hot, the gas that drives away summer heat, loose hot and suffocating; Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; All medicines are ministerial drug altogether, with principal drug assistance expelling pathogenic factors from the exterior heat extraction.Radix Bupleuri body constitution is gently clear, and abnormal smells from the patient is all thin, full of fragrance, and the main liter of property falls apart, can and few sun, remove stagnant heat, loose pathogen, thoroughly flesh table, making the heresy of heat-damp in summer thoroughly reach hinge and separate in flesh table, is adjuvant.All medicines share, and play that expelling pathogenic factors from the exterior expels the heat-evil, the merit of removing dampness removing toxic substances altogether, make wet reducing phlegm and internal heat move back then sick spontaneous recovery.
Four, attending effectiveness
Expelling pathogenic factors from the exterior heat clearing away, dispelling phlegm and relieving sore-throat, help digestion removing dampness.Heating, pharyngalgia, cough, greasy fur etc. are seen for summer-heat damp cold card.
Five, criterion of therapeutical effect is effective
After taking medicine 1, body temperature is down to normally, without bounce-back; Effective: after taking medicine 1, body temperature gradually falls, and all diseases alleviate; Invalid: after taking medicine 1 day, body temperature is not down to normally.
Six, result
Effective 45 examples for the treatment of group, effective 14 examples, invalid 1 example, total effective rate is 97%, effective 12 examples of matched group, and effective 20 examples, invalid 28 examples, total effective rate is 53.33%.
Seven, invention good effect
Fragrant a kind of reed mentioned in ancient books soup or the antipyretic granule of fragrant a kind of reed mentioned in ancient books, have the merit of expelling pathogenic factors from the exterior heat clearing away, dispelling phlegm and relieving sore-throat, the removing dampness that helps digestion, and have the advantage fast, short treating period, medical expense are low of bringing down a fever.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further, but be not limited to embodiment.
Embodiment 1
The antipyretic granule of a kind of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g.Radix Bupleuri, Herba Pogostemonis, Fructus Forsythiae steam reflux, extract, volatile oil, remaining medicinal residues and all the other four Chinese medicines decoct jointly makes dried cream powder end, then is prepared from inclusion essential oil, and the ratio of volatile oil/beta-schardinger dextrin-is 1:10, enclose temperature is 40 DEG C, and the enclose time is 60min.
Embodiment 2
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Ramulus Cinnamomi 5-15g, Radix Puerariae 5-15g.All the other are with embodiment 1.
Embodiment 3
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Radix Angelicae Dahuricae 5-15g, Rhizoma Et Radix Notopterygii 5-15g.All the other are with embodiment 1.
Embodiment 4
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Radix Peucedani 5-15g, Rhizoma Cynanchi Stauntonii 5-15g.All the other are with embodiment 1.
Embodiment 5
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Rhizoma Pinelliae Preparata 5-15g.All the other are with embodiment 1.
Embodiment 6
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Massa Medicata Fermentata 5-15g.All the other are with embodiment 1.
Embodiment 7
The antipyretic granule of fragrant a kind of reed mentioned in ancient books, is made up of the medicine of following weight portion: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Semen Raphani 5-15g.All the other are with embodiment 1.
Claims (1)
1. the antipyretic granule of fragrant a kind of reed mentioned in ancient books, is characterized in that, crude drug is made up of the medicine of following weight: Herba Pogostemonis 5-15g, Radix Scutellariae 5-15g, Fructus Forsythiae 5-15g, Folium Isatidis 5-15g, Gypsum Fibrosum 10-20g, Herba Artemisiae Annuae 10-20g, Radix Bupleuri 5-15g, Radix Peucedani 5-15g, Rhizoma Cynanchi Stauntonii 5-15g.
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| CN104367941A (en) * | 2014-11-03 | 2015-02-25 | 山东瑞康生命科技有限公司 | Preparation method of traditional Chinese medicinal preparation for treating singapore hemorrhagic fever |
| CN104689029A (en) * | 2014-11-28 | 2015-06-10 | 严淇 | Traditional Chinese medicine composition for treating exogenous high fever and preparation method thereof |
| CN104825972B (en) * | 2015-05-25 | 2018-07-27 | 辽宁阔安生物科技有限公司 | A kind of vinegar leaching Chinese herbal ultra-fine powder preparation of prevention farm animal and bird plague |
| CN107362301B (en) * | 2017-08-25 | 2021-06-25 | 云南中医药大学 | Xiangling appetizing granules |
| CN111617227A (en) * | 2020-07-17 | 2020-09-04 | 汉方泰药生物科技(宁波)有限公司 | Traditional Chinese medicine for treating pestilence qi infection |
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Non-Patent Citations (3)
| Title |
|---|
| 小儿发热治验撷要;王进进等;《中华中医药杂志》;20130430;第28卷(第4期);994-996 * |
| 柴藿颗粒制备工艺和药效学筛选工艺的研究;阳敬;《中国优秀硕士学位论文全文数据库 工程科技I辑》;20130715(第07期);B016-200 * |
| 熊磊教授治疗小儿发热常用药对介绍;赵毅涛等;《云南中医学院学报》;20051231;第28卷(第4期);48-50 * |
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Address after: 650000 Guanshang Town, Kunming City, Yunnan Province Patentee after: Yunnan University of Traditional Chinese Medicine Address before: 650000 Guanshang Town, Kunming City, Yunnan Province Patentee before: YUNNAN University OF TRADITIONAL CHINESE MEDICINE |