CN103796639B - 阳离子水包油乳液 - Google Patents
阳离子水包油乳液 Download PDFInfo
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- CN103796639B CN103796639B CN201280033539.6A CN201280033539A CN103796639B CN 103796639 B CN103796639 B CN 103796639B CN 201280033539 A CN201280033539 A CN 201280033539A CN 103796639 B CN103796639 B CN 103796639B
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Virology (AREA)
- Microbiology (AREA)
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- Mycology (AREA)
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- Organic Chemistry (AREA)
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- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
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- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161505109P | 2011-07-06 | 2011-07-06 | |
| US61/505,109 | 2011-07-06 | ||
| US201161545936P | 2011-10-11 | 2011-10-11 | |
| US61/545,936 | 2011-10-11 | ||
| US201261585641P | 2012-01-11 | 2012-01-11 | |
| US61/585,641 | 2012-01-11 | ||
| PCT/US2012/045845 WO2013006837A1 (en) | 2011-07-06 | 2012-07-06 | Cationic oil-in-water emulsions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103796639A CN103796639A (zh) | 2014-05-14 |
| CN103796639B true CN103796639B (zh) | 2017-05-31 |
Family
ID=46604537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280033539.6A Active CN103796639B (zh) | 2011-07-06 | 2012-07-06 | 阳离子水包油乳液 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9636410B2 (enExample) |
| EP (2) | EP3456316A1 (enExample) |
| JP (2) | JP6120839B2 (enExample) |
| CN (1) | CN103796639B (enExample) |
| AU (2) | AU2012280904B2 (enExample) |
| BR (1) | BR112014000235A8 (enExample) |
| CA (1) | CA2840965C (enExample) |
| ES (1) | ES2702318T3 (enExample) |
| MX (1) | MX350258B (enExample) |
| RU (1) | RU2649133C2 (enExample) |
| SG (1) | SG10201605500TA (enExample) |
| WO (1) | WO2013006837A1 (enExample) |
Families Citing this family (129)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2646669T3 (es) | 2010-07-06 | 2017-12-14 | Glaxosmithkline Biologicals Sa | Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN |
| HUE026646T2 (en) | 2010-07-06 | 2016-07-28 | Glaxosmithkline Biologicals Sa | Preferred liposomes containing lipids of PKA value for delivery of RNA |
| ES2586580T3 (es) | 2010-07-06 | 2016-10-17 | Glaxosmithkline Biologicals Sa | Inmunización de mamíferos grandes con dosis bajas de ARN |
| US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| DK4226941T3 (da) | 2010-08-31 | 2024-12-02 | Glaxosmithkline Biologicals Sa | Pegylerede liposomer til levering af immunogen-kodende rna |
| CA2821992A1 (en) | 2010-10-01 | 2012-04-05 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| KR102266691B1 (ko) | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
| DE12722942T1 (de) | 2011-03-31 | 2021-09-30 | Modernatx, Inc. | Freisetzung und formulierung von manipulierten nukleinsäuren |
| JP6184945B2 (ja) | 2011-06-08 | 2017-08-23 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | mRNA送達のための脂質ナノ粒子組成物および方法 |
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| MX350258B (es) | 2017-08-31 |
| JP2014522841A (ja) | 2014-09-08 |
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| AU2012280904A1 (en) | 2013-05-09 |
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| US20140220083A1 (en) | 2014-08-07 |
| US9636410B2 (en) | 2017-05-02 |
| ES2702318T3 (es) | 2019-02-28 |
| RU2649133C2 (ru) | 2018-03-29 |
| AU2012280904B2 (en) | 2017-02-23 |
| EP2729124B1 (en) | 2018-10-24 |
| EP2729124A1 (en) | 2014-05-14 |
| JP6120839B2 (ja) | 2017-04-26 |
| US20190091329A1 (en) | 2019-03-28 |
| BR112014000235A8 (pt) | 2018-03-06 |
| CA2840965C (en) | 2021-03-02 |
| JP2016210792A (ja) | 2016-12-15 |
| CN103796639A (zh) | 2014-05-14 |
| US11167028B2 (en) | 2021-11-09 |
| EP3456316A1 (en) | 2019-03-20 |
| WO2013006837A1 (en) | 2013-01-10 |
| CA2840965A1 (en) | 2013-01-10 |
| US10183074B2 (en) | 2019-01-22 |
| BR112014000235A2 (pt) | 2017-02-14 |
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