AU5068999A - Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier - Google Patents

Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier

Info

Publication number
AU5068999A
AU5068999A AU50689/99A AU5068999A AU5068999A AU 5068999 A AU5068999 A AU 5068999A AU 50689/99 A AU50689/99 A AU 50689/99A AU 5068999 A AU5068999 A AU 5068999A AU 5068999 A AU5068999 A AU 5068999A
Authority
AU
Australia
Prior art keywords
gene
lipid
drug carrier
emulsion
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU50689/99A
Inventor
Hesson Chung
Seo Young Jeong
Ick Chan Kwon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Advanced Institute of Science and Technology KAIST
Original Assignee
Korea Advanced Institute of Science and Technology KAIST
Korea Institute of Science and Technology KIST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Advanced Institute of Science and Technology KAIST, Korea Institute of Science and Technology KIST filed Critical Korea Advanced Institute of Science and Technology KAIST
Publication of AU5068999A publication Critical patent/AU5068999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU50689/99A 1998-07-31 1999-07-30 Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier Abandoned AU5068999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR19980031249 1998-07-31
KR9831249 1998-07-31
PCT/KR1999/000414 WO2000006120A1 (en) 1998-07-31 1999-07-30 Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier

Publications (1)

Publication Number Publication Date
AU5068999A true AU5068999A (en) 2000-02-21

Family

ID=19546046

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50689/99A Abandoned AU5068999A (en) 1998-07-31 1999-07-30 Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier

Country Status (5)

Country Link
EP (1) EP1100464A1 (en)
JP (1) JP2002521423A (en)
KR (1) KR100374482B1 (en)
AU (1) AU5068999A (en)
WO (1) WO2000006120A1 (en)

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DE60020677T2 (en) 1999-02-26 2006-05-04 Chiron Corp., Emeryville MICROEMULSIONS WITH ADSORBED MACROMOLECULES AND MICROPARTICLES
TR200103333T2 (en) * 1999-05-20 2002-04-22 Pharmasol Gmbh Auxiliary drug (SBA) that improves endurance and biological compatibility
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
AU5454801A (en) * 2000-04-20 2001-11-07 Univ British Columbia Methods of enhancing splp-mediated transfection using endosomal membrane destabilizers
JP2001300287A (en) * 2000-04-20 2001-10-30 Nof Corp Perfluorocarbon emulsifying preparation
US7189705B2 (en) 2000-04-20 2007-03-13 The University Of British Columbia Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
KR100618033B1 (en) * 2004-06-21 2006-08-30 에이엔에이치 케어연구소(주) Topical Composition Comprising Doxepin as an Active Ingredient for Curing Atopy
US20100260819A1 (en) 2005-08-11 2010-10-14 University Of Saskatchewan Reducing post-operative adhesion formation with intraperitoneal glutamine
US8530436B2 (en) * 2007-01-29 2013-09-10 Transderm, Inc. Methods and compositions for transdermal delivery of nucleotides
CA2578647A1 (en) * 2007-02-15 2008-08-15 University Of Saskatchewan Reducing post-operative adhesion formation with intraperitoneal glutamine
EP2306978A2 (en) 2008-06-06 2011-04-13 Mirna Therapeutics, Inc. Compositions for the in vivo delivery of rnai agents
GB0901857D0 (en) * 2009-02-05 2009-03-11 Nanoco Technologies Ltd Encapsulated nanoparticles
EA013570B1 (en) * 2009-02-24 2010-06-30 Ооо "Научно-Производственный Комплекс "Наносистема"" Pharmaceutical composition for treating tuberculosis and diseases mediated by helicobacter pylori based on solid lipid nanoparticles and a method for the treatment of tuberculosis
ES2351756B1 (en) 2009-07-28 2011-10-05 Universidad Del Pais Vasco LIPID NANOPARTICLES FOR GENE THERAPY.
CA3044884A1 (en) 2009-12-07 2011-06-16 Arbutus Biopharma Corporation Compositions for nucleic acid delivery
DE102010013064A1 (en) 2010-03-26 2011-12-15 Gabriele Blume Novel carrier system for the transport of active ingredients into the skin
CN103327963A (en) * 2010-07-06 2013-09-25 诺华股份有限公司 Cationic oil-in-water emulsions
ES2385080B1 (en) * 2010-12-21 2013-05-10 Universidad Del Pais Vasco-Euskal Herriko Unibertsitatea LIPID NANOPARTICLES FOR THE TREATMENT OF EYE DISEASES.
PL2717893T3 (en) 2011-06-08 2019-12-31 Translate Bio, Inc. Lipid nanoparticle compositions and methods for mrna delivery
CA2840965C (en) * 2011-07-06 2021-03-02 Novartis Ag Cationic oil-in-water emulsions
CN107596518B (en) 2012-02-29 2021-04-23 普马特里克斯营业公司 Inhalable dry powder
US9693936B2 (en) 2012-03-07 2017-07-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Dispersions in oil of Dead Sea nano sized material preparation and uses therof
CN102670484B (en) * 2012-05-30 2013-06-05 浙江大学 Mannose-modified solid lipid nanoparticle plural gel and preparation method thereof
BR102012015756A2 (en) * 2012-06-26 2014-12-02 Univ Fed De Ouro Preto Ufop PROCEDURE FOR OBTAINING HIGH CONCENTRATIONS OF THE CHEMICAL CONSTITUTE TRANS-PINOCARVILLE ACETATE FOR HYDRODESTILATION OF THE GRAVEOLEN AIR PARTIES AND OBTAINING NANOEMULSIONAL FORMULATIONS.
JP6357481B2 (en) * 2012-11-30 2018-07-11 インスメッド， インコーポレイテッド Prostacyclin compounds and methods of using prostacyclin compounds
US20140271923A1 (en) 2013-03-14 2014-09-18 Christopher Brian Reid Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions
US20140275261A1 (en) * 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
MX2020004912A (en) 2013-10-25 2021-05-21 Insmed Inc Prostacyclin compounds, compositions and methods of use thereof.
KR101671864B1 (en) * 2014-08-29 2016-11-04 세종대학교 산학협력단 Cationic emulsion containing iodized oil and use of the cationic emulsion for promoting gene delivery of virus vector
EA201790977A1 (en) 2014-11-05 2017-10-31 Селекта Байосайенсиз, Инк. METHODS AND COMPOSITIONS RELATED TO THE APPLICATION OF SURFACE-ACTIVE SUBSTANCES WITH A LOW INDICATOR OF HYDROPHILIC LIPOFILE BALANCE (HLB) WHEN OBTAINING SYNTHETIC NANOSOPHYSIC BALANCE WRITTING OTHERS, please, please use your address;
CA2967385C (en) 2014-11-18 2023-05-16 Insmed Incorporated Methods of manufacturing treprostinil and treprostinil derivative prodrugs
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
BR102017016440A2 (en) * 2017-07-31 2019-03-19 Universidade Federal Do Rio Grande Do Sul COMPOSITION FOR CENTRAL NERVOUS SYSTEM GENE THERAPY, OBTAINING AND USE PROCESS
CA3138530A1 (en) 2019-04-29 2020-11-05 Insmed Incorporated Dry powder compositions of treprostinil prodrugs and methods of use thereof
CN111281982B (en) * 2020-02-19 2023-11-17 深圳厚存纳米药业有限公司 Poloxamer and/or poloxamer and lipid combined compound
CA3174988A1 (en) 2020-03-11 2021-09-16 Selecta Biosciences, Inc. Methods and compositions related to synthetic nanocarriers
EP4056038A1 (en) * 2021-03-10 2022-09-14 Basf Se Microparticles containing active substances
CN113350521B (en) * 2021-04-08 2022-11-29 上海大学 LPD nano liposome and preparation method and application thereof
CN113877000B (en) * 2021-10-13 2023-01-24 科笛生物医药(无锡)有限公司 Microsphere composition for injection and application thereof
CN114657147B (en) * 2022-01-27 2023-12-01 安徽智飞龙科马生物制药有限公司 Protective agent for biological material and application thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0344314A (en) * 1989-07-13 1991-02-26 Nippon Petrochem Co Ltd Hair dyeing assistant for acid dye
DE4039063A1 (en) * 1990-12-07 1992-06-11 Wella Ag HAIR CURING IN THE FORM OF A MICROEMULSION
JPH06508555A (en) * 1991-06-27 1994-09-29 エモリイ・ユニバーシテイ Multiphase emulsion and manufacturing method
JPH06219940A (en) * 1993-01-27 1994-08-09 Shiseido Co Ltd Patch
AU4868396A (en) * 1995-02-22 1996-09-11 Bausch & Lomb Incorporated Skin care composition

Also Published As

Publication number Publication date
EP1100464A1 (en) 2001-05-23
JP2002521423A (en) 2002-07-16
KR20020033665A (en) 2002-05-07
KR100374482B1 (en) 2003-03-03
WO2000006120A1 (en) 2000-02-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase