Summary of the invention
The object of this invention is to provide a kind of external application of Chinese medicine agent for the treatment of facial dermatitis.The traditional Chinese medical science thinks that primary disease is due to innate deficiency, and fur space between skin and muscles is not solid, and multiple sense poison is evil, and fall ill scorchingly hot accumulateing in skin.Treatment should be with clearing away heat-damp and promoting diuresis, and removing pathogenic heat from blood and toxic substance from the body is main.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine external agent of this treatment facial dermatitis is made up of the Chinese medicine of following weight portion: Flos Hibisci Mutabilis 6-9 part, Herba Centellae 3-9 part, Herba Odontitis Serotinae 30-60 part, Radix Fici Angustipoliae 9-15 part, Herba Eragrostidis tenellae 15-30 part, Delphinium brunonianum Royle 9-15 part, Herba Adianti Flabellulati 6-15 part, Herba Sidae Rhombifoliae 5-15 part.
Preferred: 7.5 parts of Flos Hibisci Mutabiliss, 6 parts of Herba Centellaes, 45 parts of Herba Odontitis Serotinae, 12 parts of Radix Fici Angustipoliae, 22.5 parts of Herba Eragrostidis tenellae, 12 parts of Delphinium brunonianum Royle, 10.5 parts of Herba Adianti Flabellulatis, 10 parts of Herba Sidae Rhombifoliaes.
Preparation method: above medicine is added to appropriate Cera Flava, Oleum sesami, be boiled into cream.
In side: Flos Hibisci Mutabilis: clearing away heat and cooling blood, removing toxic substances, detumescence; Herba Centellae: heat clearing and damp drying, removing toxic substances, detumescence; Herba Odontitis Serotinae: heat clearing and damp drying, cooling blood and relieving pain; Radix Fici Angustipoliae: heat-clearing and toxic substances removing, expelling wind and removing dampness; Herba Eragrostidis tenellae: clearing away heat and cooling blood; Delphinium brunonianum Royle: removing heat from blood, removing toxic substances, dispelling wind for relieving itching; Herba Adianti Flabellulati: clearing away heat-damp and promoting diuresis, dissipating blood stasis for subsidence of swelling; Herba Sidae Rhombifoliae: clearing away heat-damp and promoting diuresis, the evacuation of pus of invigorating blood circulation.
Clinical data
1. the routine patient of physical data 62 all carrys out the outpatient service of self-section, divides at random 2 groups. and be treatment group and matched group.Treatment group 31 examples, wherein male's 8 examples, women's 23 examples; Age 17-65 year, 34.1 years old mean age; Wherein cosmetic dermatitis 15 examples (having obvious cosmetics contact history), contact dermatitis 6 examples, seborrheic dermatitis 5 examples, steroid-dependent dermatitis 5 examples; The shortest 2h of sick time, the longest 2 years.Matched group 31 examples, wherein male's 7 examples, women's 24 examples; Age 16-61 year, 32.2 years old mean age; Wherein cosmetic dermatitis 13 examples, contact dermatitis 7 examples, seborrheic dermatitis 4 examples, steroid-dependent dermatitis 7 examples; The square 1.5h of sick time, the longest 2 years.62 routine patients all meet clinical criteria.
Not inclusion criteria: 1. test is taken or external steroid hormones for first 1 week; 2. suffering from other may affect experimental observation skin of face patient, as psoriasis, erythema multiforme etc.
2. Therapeutic Method treatment group patient external application external application of Chinese medicine agent of the present invention, take Flos Hibisci Mutabilis 7.5g, Herba Centellae 6g, Herba Odontitis Serotinae 45g, Radix Fici Angustipoliae 12g, Herba Eragrostidis tenellae 22.5g, Delphinium brunonianum Royle 12g, Herba Adianti Flabellulati 10.5g, Herba Sidae Rhombifoliae 10g, add appropriate Cera Flava, Oleum sesami, be boiled into cream, when treatment, first with the clean skin of face of normal saline, again by the very thin Rhizoma Coptidis extractum facial skin lesion position that is coated in, then with the cold spray machine of anion to the affected part 20rain that sprays, wipe gently facial moisture and ointment away, every day 2 times with sterile gauze.Matched group: be coated in skin lesion place with Calamine Lotion, every day 2 times, treatment group and matched group be oral chlorphenamine 4mg all, every day 3 times.It within 2 weeks, is a course for the treatment of.
3. criterion of therapeutical effect was used in conjunction after 1 course for the treatment of, and flush, dry desquamation, pigment, acneform eruptions and pruritus sense of discomfort are evaluated.Recovery from illness: skin lesion is disappeared completely, and subjective symptoms disappears completely.Effective: the skin lesion > 70% that disappears.Subjective symptoms disappears completely.Effective: skin lesion disappears 30%~70%.Subjective symptoms alleviates.Invalid: the skin lesion < 30% that disappears, subjective symptoms is not improved.
4. the rear curative effect of two groups of treatments of therapeutic outcome is relatively in table 1.
Curative effect comparison after table 1 liang group treatment
Effectively (%) invalid (%) total effective rate (%) of the total number of cases recovery from illness of group (%) effective (%) |
Treatment group 3115 (48.39) 11 (35.48) 3 (9.68) 2 (6.45) 29 (93.55) |
Matched group 312 (6.45) 5 (16.13) 11 (35.48) 13 (41.94) 18 (58.06) |
Two groups of comparison treatment group cure rates, total effective rates are obviously better than matched group cure rate, total effective rate, have significant difference (P < 0.05).
The specific embodiment
Embodiment mono-: take Flos Hibisci Mutabilis 7.5g, Herba Centellae 6g, Herba Odontitis Serotinae 45g, Radix Fici Angustipoliae 12g, Herba Eragrostidis tenellae 22.5g, Delphinium brunonianum Royle 12g, Herba Adianti Flabellulati 10.5g, Herba Sidae Rhombifoliae 10g, get corresponding equal portions said medicine and add appropriate Cera Flava, Oleum sesami, be boiled into cream.
Embodiment bis-: take Flos Hibisci Mutabilis 6g, Herba Centellae 3g, Herba Odontitis Serotinae 30g, Radix Fici Angustipoliae 9g, Herba Eragrostidis tenellae 15g, Delphinium brunonianum Royle 9g, Herba Adianti Flabellulati 6g, Herba Sidae Rhombifoliae 5g, get corresponding equal portions said medicine and add appropriate Cera Flava, Oleum sesami, be boiled into cream.
Embodiment tri-: take Flos Hibisci Mutabilis 9g, Herba Centellae 9g, Herba Odontitis Serotinae 60g, Radix Fici Angustipoliae 15g, Herba Eragrostidis tenellae 30g, Delphinium brunonianum Royle 15g, Herba Adianti Flabellulati 15g, Herba Sidae Rhombifoliae 15g, get corresponding equal portions said medicine and add appropriate Cera Flava, Oleum sesami, be boiled into cream.