CN104043003A - Liquid medicine for external use for treating dermatoses - Google Patents

Abstract

The invention provides a liquid traditional Chinese medicine. The liquid medicine is prepared by performing water-phase extraction on traditional Chinese medicinal materials such as solanum indicum, stigma croci, cortex phellodendri, rheum officinale, gleditsia sinensis thorns, radix stemonae and macleaya cordata. The liquid medicine is applied to topical treatment of red and swollen skin, erosion, eczema, psoriasis, acne, whelk, dermatophytosis and insect bites and stings, and has the advantages of quick curative effect and low toxic and side effects.

Description

One is treated dermopathic lotion

Technical field

The invention belongs to tcm field, relate to one and treat dermopathic lotion.

Background technology

Skin is the outermost protective tissue of human body, is also the organ of human body maximum, is mainly bearing the function of protecting health, perspire, feeling cold and hot and pressure.Skin covers whole body, and it makes the interior various tissues of body and organ avoid the invasion and attack of physical property, mechanicalness, chemical and pathogenic microorganism.Also its outermost layer in human body just, is subject to the impact of outside various biology, chemistry, physical action unavoidably, such as situations such as fungal infection, wound, allergy, poisoning, viral infection.The multiplex antibacterial-anti-inflammatory drug of this type of dermatosis of existing treatment, has aerosol (YUNNAN BAIYAO), unguentum (dexamethasone acetate) etc., and these medicines are used widely as nonprescription drugs.But these Drug therapy windows are narrow, such as YUNNAN BAIYAO is better for traumatism treatment effect, it mainly contains antibacterial and medical material blood circulation promoting and blood stasis dispelling, can promote local blood and flow, and the provisioning that has additional nutrients, promotes wound healing.Do not act on for fungus, courses of infection, mosquito bite.And common dermatologic dexamethasone acetate has antiinflammatory, antiallergic, Antishock function.But as adrenocortical hormone medicine, itself have multiple side effect, as immunosuppressant, resistance declines, easy infection; Tissue metabolism is vigorous, and wound is not easy to grow; Abnormal carbohydrate metabolism, occurs or diabetes is increased the weight of; Adrenal cortex function suppresses; Peptic ulcer; Seborrheic dermatitis etc.

China is Chinese Traditional Medicine big country, and various crude drugs are very abundant, that many Chinese medicine materials all have is antibacterial, antiviral, invigorate blood circulation, removing toxic substances, antiinflammatory, the harmless effect of low toxicity.The present invention is according to Chinese materia medica principle, and the Chinese crude drug that filters out specific drug effect is studied, processed, and is prepared into and is applicable to preparation used in everyday, for treating for skin disease.

Technology contents

The object of this invention is to provide one and treat red swelling of the skin, erosion, the external application Chinese medicine liquid medicine of the diseases such as eczema, tinea, acne, comedo, beriberi, mosquito bite.

Chinese medicine liquid medicine of the present invention is made up through effective component extracting of the Chinese crude drug of following kind:

Fructus Solani Khasiani, Stigma Croci, Cortex Phellodendri, Radix Et Rhizoma Rhei, Fructus Gleditsia acupuncture, the Radix Stemonae, Herba Macleayae Cordatae.

Chinese medicine liquid medicine of the present invention, its active component is made up after extracting of following weight portion Chinese crude drug:

12 parts of Fructus Solani Khasiani, 15 parts of Stigma Crocis, 20 parts of Cortex Phellodendris, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Fructus Gleditsia acupunctures, 13 parts of the Radixs Stemonae, 20 parts of Herba Macleayae Cordatae.

It is as follows that the present invention treats the pharmacologically active of the contained effective ingredient of dermopathic lotion:

Fructus Solani Khasiani, " Kunming conventional medical herbs among the people ": " micro-hardship, cold, slightly poisonous." enter the heart, liver, kidney three warps.Eliminating inflammation and expelling toxin, sedation-analgesia.Rheumatism treating, traumatic injury pain, nervous headache, stomachache, toothache, mastitis, parotitis.。

Stigma Croci, is a kind of famous and precious Chinese crude drug, has powerful physiologically active, and its stigma, has calmness, eliminates the phlegm as medicinal in Asia and Europe, spasmolysis, for the treatment of gastropathy, regulating menstruation, measles, heating, jaundice, hepatosplenomegaly etc.

Cortex Phellodendri, bitter in the mouth, cold in nature.Return kidney, bladder, large intestine channel.Heat clearing away.Dampness, pathogenic fire purging, removing toxic substances.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.

Radix Et Rhizoma Rhei, bitter in the mouth, cold in nature.Return spleen, stomach, large intestine, liver, pericardium channel.Attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.

Fructus Gleditsia acupuncture, searches wind, draws out pus by applying a plaster to the affected part, and detumescence, evacuation of pus.Control carbuncle, sore, leprosy, tinea skin ulcer, placenta retention." Amplification on Materia Medica addendum ": control carbuncle routed, can cause the place that bursts." detailed outline ": control carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing." book on Chinese herbal medicine is high former ": remove air slaking expectorant, counteracting toxic substances relieves internal heat.

The Radix Stemonae, sweet in the mouth, hardship, slightly warm in nature.Return lung meridian.Nourishing the lung to arrest cough; Parasite killing delousing.Main new chronic cough is coughed; Pulmonary tuberculosis; Pertussis; Enterobiasis; Body louse; Tinea scabies.For nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outward for head louse, body louse, enterobiasis, pudendum Pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough.

Herba Macleayae Cordatae, " Traditional Chinese Medicine in Sichuan will ": toil, temperature.Detumescence, removing toxic substances, parasite killing.Control furuncle of finger, abscess, acute tonsillitis, otitis media, trichomonal vaginitis, ulcer of the lower limb, scalds stubborn dermatitis." Jiangxi traditional herbal medicine ": control ecthyma, stubborn dermatitis, white baldhead, soaks in vinegar seven, eight with leaf, and the rotten deposited affected part of pestle, changes for one day one." Hunan medicine will ": the removing toxic substances of dispeling the wind, promoting the circulation of QI for relieving swelling, parasite killing.

The present invention treats dermopathic lotion, selected Chinese crude drug is not that simple effect is cumulative, to there is sufficient pharmacology's compatibility basis and actual clinical medication experience, formation has the clinical proved recipe of definite effect, active compound has antiinflammatory, parasite killing, sterilization, removing toxic substances, calmness, pain relieving, detumescence, heat clearing away, the effect of invigorating blood circulation of general character, and effect is complemented each other, and the property of medicine sets off mutually, mutually merge.

The present invention treats the lotion of multiple dermatosis, and advantage is: 1, treatment window is wide, regulates by system, and for various red swelling of the skin, erosion, eczema, tinea, acne, comedo, beriberi, mosquito bite all have better effects.2, crude drug source is convenient, and inexpensive, liquid medicine of the present invention is pure Chinese medicinal preparation, and toxic and side effects is little.

Clinical efficacy

1. sample information

Sample case is the multiple situation dermatosis patient of curing for many years.Age reckling 12 years old, the oldest person 76 years old.Patient is the red swelling of the skin, the erosion that are had in various degree, the symptoms such as eczema, tinea, acne, comedo, beriberi, mosquito bite.All use liquid medicine of the present invention to treat.

2. Therapeutic Method

Select Chinese medicine of the present invention, after allotment, in marmite, add 10 times of water gagings and decoct 40 minutes in proportion, cooling, elimination medicinal residues, Pharmaceutical bottling, does washing liquid and uses, and uses 20～30mL liquid medicine to clean affected part, every day 1～2 time, 5 days courses for the treatment of according to the state of an illness at every turn.

3. therapeutic outcome

Clinical treatment patient 157 examples, generally through 2～3 course of therapy, recovery from illness 114 examples, effective 16 examples, effective 14 examples, invalid 13 examples, total effective rate 91.7%.The intractable tinea that sick time is long, needs long period treatment.

4. model case

(1), Huang, man, 38 years old.Patient sends out eczema since in May, 2012, and two forearms were itched before this, plays the granular pimple of chestnut, then the granular pimple of chestnut is also played in left leg inner side, and pruritus is unbearable, and afternoon more so, the pimple of affected part gradually is all festered, and oozes out yellow liquid, and rear use external preparation for skin liquid medicine of the present invention is sprayed on affected part, every day twice, used after the course for the treatment of, had no new life's pimple, also without pruritus, then use after second course for the treatment of, various symptom recoveries from illness, follow up a case by regular visits to and have no recurrence half a year.

(2), thunder so-and-so, man, 18 years old.Start patient and in April, 2012 to send out a comedo, once used the oral and outer painting hormone medicine of several different methods, but effect not obvious, visible grain of rice shape size small pox spreads all over buccal and forehead, and whole face goes out Chuck Steak, and buccal portion small pox merges in flakes, color is red, there is wrist bleb tip, two courses for the treatment of of rear lasting use external preparation for skin liquid medicine of the present invention, fasting maror, skin of face situation is improved greatly, pus born of the same parents recovery from illness, complexion changed is light, and comedo disappears substantially.

(3), Liu so-and-so, female, 28 years old.Patient suffers from comedo existing more than ten years, and fat secretion is vigorous on the face, overgrows with the little pimple of pink colour, high height is low, rough and uneven in surface, have also with exanthema vesiculosum, after using a course for the treatment of of this external preparation for skin liquid medicine, situation is greatly improved, and small pox obviously flattens, and color is thin out, rear continuation was used after second course for the treatment of, red comedo all disappears, and it is smooth that skin becomes, and fat secretion on the face has also become normally.

(4) Lee so-and-so, man, 38 years old.Patient and in February, 2013 obtained beriberi, often scratched foot antipruritic, had become afterwards custom, After Hours one went home, and had taken off just scratching of footwear, after scratching, did not also wash one's hands, and also often between lower strand of scratching hip, caused the generation of tinea cruris.Femoribus internus has the activeness edge that adheres to squama of red projection as seen, has wrist bleb at edge, and pruritus is hard to bear.Through using external preparation for skin liquid medicine of the present invention to be sprayed on after the course for the treatment of of affected part, obviously visible wrist bleb is flat, and activeness edge disappears, and skin color is tending towards normally, and skin pruritus disappears, and daily routines are normal.

(5) Zhu, female, 28 years old.Patient obtained eczema in February, 2014, and little pimple in blocks appears in face and both thighs inner side, and pruritus is unbearable, then festers, and flows out yellow mucus, DeGrain after western medicine for oral administration, and state of an illness successional change, affected part forms ulcer, and pruritus is more so.Through using external preparation for skin liquid medicine of the present invention to be sprayed on after the course for the treatment of of affected part, ulcer obviously heals, and pruritus subtracts greatly, also no longer flows out yellow mucus.Then use after the course for the treatment of, ulcer surface is formed a scab comprehensively again, and pruritus is stopped, and skin smooth is cured substantially.

Specific embodiment

To clean and concoct 12 grams of rear Fructus Solani Khasiani, 15 grams of Stigma Crocis, 20 grams of Cortex Phellodendris, 10 grams of Radix Et Rhizoma Rhei, 10 grams of Fructus Gleditsia acupunctures, 13 grams of the Radixs Stemonae, 20 grams of Herba Macleayae Cordatae.Be placed in marmite, add 1.0kg water, first boil with high heat, after change into slow fire, continue to decoct 40 minutes.Cooling, elimination medicinal residues, medicinal liquid bottling, does washing liquid and uses, and uses 20～30mL liquid medicine to clean affected part, every day 1～2 time, 5 days courses for the treatment of according to the state of an illness at every turn.

Claims (1)

1. treatment red swelling of the skin, an erosion, the external application Chinese medicine liquid medicine of eczema, tinea, acne, comedo, beriberi, mosquito bite.This liquid medicine is made up after aqueous extraction of the Chinese crude drug of following part by weight:

12 parts of Fructus Solani Khasiani, 15 parts of Stigma Crocis, 20 parts of Cortex Phellodendris, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Fructus Gleditsia acupunctures, 13 parts of the Radixs Stemonae, 20 parts of Herba Macleayae Cordatae.