CN103751648A - Product for patients with hyperplasia of mammary glands - Google Patents

Abstract

The invention relates to a product for patients with hyperplasia of mammary glands, belonging to the field of traditional Chinese medicines. The product is characterized in that the product is mainly prepared from the following raw materials in parts by weight: Gekko gecko 80-150 parts, radix asparagi 60-120 parts, Fritillaria thunbergii 60-120 parts, Prunella vulgaris 60-120 parts, Gleditsia sinensis spines 20-60 parts, seaweed 40-80 parts, Liquidambar formosana 40-80 parts, Vaccaria segetalis 40-60 parts, Pseudobulbus Cremastrae Seu Pleiones 30-80 parts, Bombyx Batryticatus 20-80 parts, Herba Erodii and/or Herba Geranii 20-80 parts, Buthus martensii 20-70 parts, Hordeum vulgare sprout 20-70 parts, and processed Radix Glycyrrhizae 2-70 parts. The product can effectively regulate hormone balance in body, effectively relieve mammary swelling and pain and eliminate nodule in breast, relieve pain of breasts during menstruation, and prevent breast cancer. Through therapeutic effect clinical observation of more than 3,000 cases in 10 years, the cure rate is 95%, and the effective rate is 98%. The product provided by the invention can be used for relieving symptoms of hyperplasia of mammary glands such as breast pain, swelling pain, hard lumps and lumps.

Description

Goods for cyclomastopathy patient

Technical field

The present invention relates to the field of Chinese medicines, particularly a kind of goods for cyclomastopathy patient.

Background technology

Cyclomastopathy class disease is with the performance of its Clinical symptoms, suitable with the disease such as the traditional Chinese medical science " nodules of the breast ", " newborn pestilence ", " nodule in the breast ".In < < Huatuo's Zhongzang classic > >, just had the record of " nodules of the breast " name of disease.Gradually detailed about the discussion of " nodules of the breast " in the period of Ming and Qing, the famous surgery scholar of Ming Dynasty Chen Shigong is described and is said: " nodules of the breast is nodule in the breast, and shape is as ball ovum, or pendant recast pain, or not bitterly, color of the leather is constant, the growth and decline with susceptible to anger of its core ... ".The Zou Yue of the Qing Dynasty < < surgery of writing is really annotated in > > book and is further pointed out: " nodules of the breast; ... young and impetuous; suffering from one, two year person can dissipate; if old weakness of QI; to suffer from and not controlling through several years persons, should temperance for food and drink, cease angry, multitudinous change of exempting from breast carcinoma." point out in < < Yangke Xinde Ji, Experience Gained in Treating External Diseases > >: " it is bright that husband's breast belongs to sun, there is core in Ruzhong, how do not blame sun bright and duty liver, with the bright stomach soil of sun, fear edema with the liver involved most, irritability is to some extent relaxed, and stomach is shown in the strongly fragrant of wood, lest next gram, volt is and bad-looking, and gas dare not relax; Depression of liver-QI, and swollen hard formation; Gastric qi dare not be relaxed, and the color of fear is existing.Do not ache not redly, just seeing that it fears also.Method for the treatment of needn't be controlled stomach, but treating the liver and swollen from disappearing.”

Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and newborn lobule degeneration structurally and the growth of carrying out property connective tissue, and its pathogenic factor is mainly due to endocrine hormone imbalance.Cyclomastopathy is the modal cystic hyperplasia of breast of women, and man also has generation.Distending pain of the breast and the multiple lump in breast periodically increasing the weight of of take is main clinical characters.This disease is comparatively common, and its sickness rate of domestic report is in 10% left and right, and is mainly in 30～50 years old women.This cause of disease is because of not yet clear and definite so far, mainly thinks endocrine dysfunction with human body at present, particularly relevant with women's ovarian dysfunction.The danger of cyclomastopathy class Disease canceration exceeds 1.4～2.5 times than healthy women, especially the cystic hyperplasia rate average out to 10% that cancerates.

Modern medicine mainly divides three major types for the therapy of cyclomastopathy class disease: western medicine therapy, tcm therapy and Operative total removal.Modern western medicine lacks effective therapy for this type of disease, Western medicine takes effect slowly, weak curative effect and side effect large, so western medicine therapy is not the conventional means that is used for the treatment of cyclomastopathy.Although Operative total removal therapy is the most effective, misery greatly, easily recurrence, breast is produced to infringement, can cause physical and psychological pressure to patient.Modern Chinese medicine is treated the Clinical Papers that this disease delivers the earliest and is seen 1958, with pin treated with moxibustion, obtains certain effect.Chinese traditional treatment method variation, has Drug therapy, acupuncture, external treatment, changes folk prescription proved recipe etc., this sick curative effect of Chinese traditional treatment, by the early days of foundation 65% rise to 90% current left and right, but complicated operation, use inconvenience and effect limited.

Have not yet to see fundamentally effectively cure cyclomastopathy, safety have no side effect, make simple, easy to use, cure rate is high, expense is low, Chinese prescription goods or the medicine of instant effect.

Summary of the invention

The object of the present invention is to provide a kind of goods for cyclomastopathy patient, this goods depressed liver-energy dispersing and QI regulating, pain relieving, blood circulation promoting and blood stasis dispelling, detumescence softening the hard mass, dissipating phlegm and resolving masses, effective mediation body internal hormone balance, thus play the effect of elimination distending pain of the breast and nodule in the breast tuberosity; These goods are treated distending pain of the breast during menstruation in addition simultaneously, and the effect of Breast Cancer Prevention.

For cyclomastopathy patient's goods, wherein said goods are made by the crude drug of following weight portion: Gekko Swinhonis 80-150 part, Radix Asparagi 60-120 part, Bulbus Fritillariae Thunbergii 60-120 part, Spica Prunellae 60-120 part, Spina Gleditsiae 20-60 part, Sargassum 40-80 part, Fructus Liquidambaris 40-80 part, Semen Vaccariae 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 30-80 part, Bombyx Batryticatus 20-80 part, Herba Erodii 20-80 part, Scorpio 20-70 part, Fructus Hordei Germinatus 20-70 part, Radix Glycyrrhizae Preparata 2-70 part.

The crude drug of described weight portion is: Gekko Swinhonis 80-130 part, Radix Asparagi 60-100 part, Bulbus Fritillariae Thunbergii 60-100 part, Spica Prunellae 60-100 part, Spina Gleditsiae 20-40 part, Sargassum 40-70 part, Fructus Liquidambaris 40-60 part, Semen Vaccariae 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 40-70 part, Bombyx Batryticatus 30-70 part, Herba Erodii 30-80 part, Scorpio 40-70 part, Fructus Hordei Germinatus 20-60 part, Radix Glycyrrhizae Preparata 30-70 part.

The crude drug of described weight portion is: 100 parts of Gekko Swinhoniss, 60 parts of Radix Asparagi, 80 parts of Bulbus Fritillariae Thunbergiis, 80 parts of Spica Prunellaes, 40 parts of Spina Gleditsiae, 40 parts of Sargassums, 40 parts of Fructus Liquidambaris, 40 parts of Semen Vaccariae, 60 parts of Pseudobulbus Cremastrae Seu Pleioness, 50 parts of Bombyx Batryticatus, 60 parts of Herba Erodiis, 50 parts of Scorpios, 40 parts of Fructus Hordei Germinatus, 5 parts of Radix Glycyrrhizae Preparata.

The purposes of described goods in the medicine of preparation treatment cyclomastopathy.

Treat a medicine for cyclomastopathy, its effective ingredient is described goods.

The dosage form of described medicine is pill.

Described pill is water pill.

The characteristic of goods of the present invention is: take Gekko Swinhonis as monarch, enter Liver Channel, kind softening hardness and resolving stasis, dispersing pathogen accumulation, conventional scrofula and the cancerous protuberance controlled.Radix Asparagi, Bulbus Fritillariae Thunbergii, Spica Prunellae are ministerial drug, have dissipating phlegm and resolving masses, the effect of the dissipating blood stasis that relieves inflammation or internal heat; Assistant is with Spina Gleditsiae, Sargassum, Fructus Liquidambaris, Semen Vaccariae, Pseudobulbus Cremastrae Seu Pleiones, Herba Erodii hard masses softening and resolving dredging collateral, Scorpio, Bombyx Batryticatus dredge the meridian passage, through sick institute, Fructus Hordei Germinatus belongs to food stagnation removing class medicine, enters Liver and kidney warp, to be dissipated as master, can help digestion and in, again can soothing the liverization stagnant, and have the merit of invigorating the spleen and regulating the stomach galactopoiesis.Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription, for we make medicine.All medicines share, and dispersing liver-energy is melted in the side of making, and adjust punching to appoint, dissipating blood stasis knot, and medicine is in a stove, and making to swell and ache disappears in invisible.Described goods have depressed liver-energy dispersing and QI regulating, pain relieving, blood circulation promoting and blood stasis dispelling, detumescence softening the hard mass, the drug effects such as dissipating phlegm and resolving masses.These goods are that pure Chinese medicinal preparation has no side effect, effective mediation body internal hormone balance, thus play the effect of eliminating distending pain of the breast and nodule in the breast tuberosity; These goods are treated distending pain of the breast during menstruation in addition simultaneously, and the effect of Breast Cancer Prevention.For distending pain of the breast, the cyclomastopathy row Disease that the scleroma that in breast, formation is differed in size is main manifestations, through clinical 10 years more than 3,000 routine patients' observation of curative effect, 1-5 course cure rate 95%, effective percentage 98%.

The crude drug that goods of the present invention adopt is described below:

Gekko Swinhonis: be dry all without web Gekko Swinhonis (Gekko swinhoana Gunther), Gekko japonicus (G.japonicum Doumeril et Bibron), Gekko Swinhonis (G.chinensis Gray) of Gekkonidae animal.Summer, two seasons of autumn catch, and catch rear execution, dry or dry.Property salty, cold.Mild toxicity.Return Liver Channel.There is expelling wind for relieving convulsion, the effect of detoxicating and resolving stagnation of pathogens, for paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula malignant boil.Goods of the present invention be take Gekko Swinhonis as monarch, enter Liver Channel, kind softening hardness and resolving stasis, dispersing pathogen accumulation, conventional scrofula and the cancerous protuberance controlled.

Radix Asparagi: Asparagus cochinchinensis (Lour.) Merr is Liliaceae, asparagus plant.Property sweet, bitter, cold.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Can be used for dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, diphtheria, fever due to yin deficiency, cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation, dysuria.And there is the free radical of removing and inhibition of lipid peroxidation, and blood sugar lowering, antibacterial, antitumor, the pharmacological actions such as relieving cough and expelling phlegm.

Bulbus Fritillariae Thunbergii: Fritillaria thunbergii Miq. is Liliaceae, Fritillaria Linn, perennial herb.The large hardship of taste, cold in nature.Start with lunar, few positive, bright, the moon of fainting of foot sun.There is removing heat-phlegm, the effect of powder detoxifcation.Cure mainly cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.

Spica Prunellae: Prunella vulgaris, Labiatae Herba lamii barbati subfamily Prunella.Spica Prunellae is cold in nature, sweet in the mouth, pungent, micro-hardship, there is the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, be applicable to lymphoid tuberculosis, goiter, acute mastitis, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery etc.Modern pharmacological research shows, Spica Prunellae has the effect reducing blood pressure, and can blood vessel dilating, and its contained rutin has antiinflammatory action, and can reduce vascular permeability, reduces fragility, reduces liver fat.Spica Prunellae resists the effect of cancerous cell in addition.

Spina Gleditsiae: GleditsiasinensisLam.[G.horridaWilld.], be the Spina jujubae of pulse family deciduous tree plant Gleditsia officinalis.This product nature and flavor are pungent, temperature.Return lung meridian, Liver Channel.The special detumescence and apocenosis of merit, tcm clinical practice all has good therapeutic effect for swollen ulcer drug, generally show as pus not Cheng Zheke disappear, formed pus person can make it speed and burst.Modern times Anticancer is studied and is shown, Spina Gleditsiae has anticancer tumor-suppression activity.

Sargassum: be the dry frond of Sargassaceae plant Sargassum (Sargassum pallidum (Turn.) C.Ag.) or Sargassum fusiforme (Harv.) Setch (Sargassum fusiforme (Harv.) Setch.).The former practises title compatibile, and the latter practises and claims lobule Sargassum.Summer, Qiu Erji fish, and remove impurity, clean, and dry.Bitter in the mouth, salty, cold in nature.Return liver, stomach, kidney channel.There is hard masses softening and resolving, expectorant, diuretic, the effect such as expel the heat-evil.Be used for the treatment of scrofula, goiter, gathers, edema, beriberi, painful and swollen testis, phlegm retention edema.

Fructus Liquidambaris: Fructus Lipuidambaris Liquidambar taiwaniana Hance, for the drying and ripening infructescence of Hamamelidaceae Plants Chinese sweet gum (Liquidambar formosana Hance), the root of this plant (Radix Liquidambaris), bark (Cortex Liquidambaris), resin (Resina Liquidambaris), leaf (Folium Liquidambaris) etc. are hyoscine also.Bitter in the mouth, property is flat.Return liver, kidney channel.There is dispelling, collateral-activating, the diuretic effect such as stimulate the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.

Semen Vaccariae: be the seed of pinkwort Vaccaria segetalis (Vaccaria segetalis (Neck.) Garcke.).Annual or biennial herb.Bitter in the mouth, property is flat.Return liver, stomach warp.Promoting blood circulation to restore menstrual flow, stimulating milk secretion detumescence.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.

Pseudobulbus Cremastrae Seu Pleiones: be the dry pseudobulb of pleione bulbocodioides (Rolfe) or Pleione yunnanensis (P.yunnansis Rolfe).Bulbus Lloydiae tibeticae, the contained colchicine of iphigenia indica and add the synthetic colchicine after liquor ammoniae dilutus, all have the antitumor action similar to vinblastine.Colchicine also has tranquilizing soporific synergism.In addition, this product still has cough-relieving, relievings asthma and analgesic effect.Bulb heat clearing away, removing toxic substances, detumescence.Wai Fu Carbuncle is swollen, snakebite.Nature and flavor: herb: bitter, micro-pungent, cool.Effectiveness: herb: dispersing swelling and dissipating binds, reduce phlegm, heat-clearing and toxic substances removing.Control carbuncle furuncle and phyma, laryngopharynx swelling and pain, sore throat ， Luo Scrofulaceum.

Bombyx Batryticatus: be Bombycidae insecticide silkworm (Bombyx mori L.) the lethal dry body of larva infection (or artificial vaccination) muscardine (Beauveria bassiana (Bals.) Vuill.) in 4～5 ages.Feeble QI raw meat, taste is micro-salty.Acrid in the mouth, salty, property is flat, returns liver, lung, stomach warp.There is expelling wind to relieve convulsion, the effect of dissipating phlegm and resolving masses, clinical being used for controlled tangible enclosed mass, as tuberosity, pharyngeal swelling pain, scrofula, wind skin ulcer urticaria, convulsion with spasms, submandibular lymph nodes is scorching, facial paralysis, skin pruritus etc.Relieve internal heat anticancer, for the long-pending poison of carcinoma.All get its logical loose energy.

Herba Erodii: Erodii Herba Geranii Herba, the dry aerial parts of WeiMang Niuer Seedling section plant Mang cattle Seedling, Herba Erodii or Carolina Cranesbill Herb.Dispel the wind, invigorate blood circulation, heat-clearing and toxic substances removing.Dispelling the wind and dampness pathogens pain, contracture is numb, carbuncle, traumatic injury, enteritis, dysentery.There is antibacterial, antiviral, antidiarrheal, blood coagulation, eliminate the phlegm, the pharmacological action such as anthelmintic, inhibition gastrointestinal motility, diuresis.

Scorpio: Scorpio, acrid in the mouth, property is flat; Poisonous.Return Liver Channel.The main medicinal ingredient of Scorpio is charybdotoxin (Buthotoxin), according to < < Compendium of Materia Medica > > and < < Chinese Pharmacopoeia > >, carry, Scorpio has " spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain " function; Cure mainly diseases such as " infantile convulsion, tic spasm, dermatosis, cardiovascular and cerebrovascular disease, inflammation, hepatitis B, tumors ".Conventional take that what be used as medicine is Scorpio.Also claim Ma Shi Scorpio, belong to the Buthidae (Buthidae) of Scorpionida.The medicinal elite of Scorpio is mainly scorpion venom, scorpion venom to nervous system, digestive system, cardio-cerebrovascular, cancer, dermatosis, etc. various diseases, and the very harmful various viruses of the mankind are all had to prevention and inhibitory action.

Fructus Hordei Germinatus: be grass, Fructus Hordei Vulgaris (H.vulgare) mature fruit is germinateed dry and obtained.Sweet in the mouth, property is flat.Return spleen, stomach warp.Effect: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Cure mainly: food stagnation does not disappear, abdominal distention, insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation.

Radix Glycyrrhizae Preparata: be the Preparation process product of Radix Glycyrrhizae (Glycyrriza Uralensis Fisch.G.Glabra L.).Method for making: get clean Radix Glycyrrhizae tabellae, according to processed with honey method, fry to yellow to buff, take out when tack-free, dry in the air cool.Sweet in the mouth, property is flat.GUIXIN, spleen, lung, stomach warp.Function and curing mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.

Those skilled in the art, can content according to the present invention obtain goods of the present invention, and using these goods as effective ingredient, add pharmaceutically acceptable auxiliary element, as disintegrating agent, lubricant, binding agent, excipient, suspending agent, slow releasing agent, flavoring agent etc., with conventional method of Chinese medicinal, be prepared into medicine or the food of various dosage forms, as pill, powder, tablet, capsule, oral liquid etc.These medicines all belong to same design of the present invention, therefore also in this request, protect.

In most of embodiment of the present invention, described goods are the medicine for cyclomastopathy class Disease, and dosage form is pill, is specially water pill.Those skilled in the art know the preparation method of water pill, be about to above-mentioned all or part of crude drug and be ground into superfine powder, with cold boiled water, medicine juice or other liquid, be bonding (moistening) agent, with general method for making, make pellet shapes pill, concrete grammar is shown in the preparation method in embodiment 1.Those skilled in the art can suitably adjust the water pill (as: general No. 4 balls of water, general No. 6 balls of water etc.) for preparing different size as required, it is little that water pill has volume, and surface compact is smooth, has both been convenient to swallow, be difficult for again the moisture absorption, be conducive to the advantages such as keeping storage.

In some embodiments of the invention, the instructions of taking of described water pill is: each oral water pill that is equivalent to 6g crude drug, every day 3 times, warm water delivery service, 1 month is a course for the treatment of.General patient takes the fruit that takes effect 1 course for the treatment of.Cure 1～3 course for the treatment of.

The specific embodiment

The preparation of No. 1.1 goods of embodiment

Raw material of Chinese medicine and weight portion thereof: 100 parts of Gekko Swinhoniss, 60 parts of Radix Asparagi, 80 parts of Bulbus Fritillariae Thunbergiis, 80 parts of Spica Prunellaes, 40 parts of Spina Gleditsiae, 40 parts of Sargassums, 40 parts of Fructus Liquidambaris, 40 parts of Semen Vaccariae, 60 parts of Pseudobulbus Cremastrae Seu Pleioness, 50 parts of Bombyx Batryticatus, 60 parts of Herba Erodiis, 50 parts of Scorpios, 40 parts of Fructus Hordei Germinatus, 5 parts of Radix Glycyrrhizae Preparata.Preparation method:

The processing of step 1. raw material is pulverized: each medicine in prescription processed to concoct after qualified on request and pulverizes, and mistake 100 mesh sieves, standby.

Step 2. molding: ball mould is the basis of agitation procedure molding.There are two kinds of methods of manual molding and mechanical molding.

(1) manual molding is at clean dry bamboo plaque 1/4 place, with brush, being stained with little water coating evenly makes plaque face moistening, spread a small amount of powder on wet plaque face, with the hands hold plaque, rotate bamboo plaque, make medicine all moistening, then under brushing gently in turn with brush (being to adjust down gently with brush point), rotate bamboo plaque, granule by moistening is moved to another side (dry plaque place), sprinkle a little fine powder, and shake bamboo plaque, make granule all be stained with equably medicated powder and shake to another place, a small amount of water in former painting water place again, bread granule being moved to painting water goes out to roll again, water is all stained with, go to again another dry place, sprinkle fine powder, rotate again bamboo plaque, make wet granular all roll on medicated powder, such repeatable operation like this repeatedly, until form compared with Wei Mi little garden grain (as size diameter is about 0.5-1mm), while not being stained with plaque, plaque mould, after choosing evenly, strengthen again molding.

(2) mechanical molding by medicated powder spreading in coating pan, under coating pan rotates, water is sprayed into, make medicated powder all become moistening granule, add again a small amount of fine powder, continue rolling certain hour, make granule solid, micro-close, the dusting of spraying water again, so repeatedly operate, rule ball mould, after screening, continue again molding, (or first appropriate water is inclined in pot, if appropriate medicated powder again, evenly spreading is in whole pot, then with brush, from rightabout, brush down gently, obtain loose block, with have gentle hands, gently rub, make large fragmentation continue repeatable operation and can become ball mould.

Step 3. strengthens molding: mould rotates bamboo plaque repeatedly after making, and alternately adds water and add powder, constantly rotates medicine plaque, whole basic acts be rubbing, knock over, hocket, to strengthen pill hardness and roundness, until pill strengthens molding gradually, till meeting the requirements.

Step 4. is selected ball: with suitable medicine sieve, by the even pill always of pill screening, too small pill is general large again, and suitable processing is done in excessive lopsided should separating.

Step 5. capping: the object of capping is to make pill surface compact, bright and clean, and color and luster is consistent.Conventional method has three kinds of dry powder capping, clear water capping and clean plasm cappings.

Step 6. is dry: because the watered pill water yield is larger, should be dried in time (60 degree are following).When dry, should heat up gradually, and constantly stir, in order to avoid produce male and female face.After dry, both obtained water pill.

The preparation of No. 2.2 goods of embodiment

Raw material of Chinese medicine and weight portion thereof: 80 parts of Gekko Swinhoniss, 60 parts of Radix Asparagi, 60 parts of Bulbus Fritillariae Thunbergiis, 60 parts of Spica Prunellaes, 20 parts of Spina Gleditsiae, 40 parts of Sargassums, 40 parts of Fructus Liquidambaris, 40 parts of Semen Vaccariae, 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 20 parts of Bombyx Batryticatus, 20 parts of Herba Erodiis, 20 parts of Scorpios, 20 parts of Fructus Hordei Germinatus, 2 parts of Radix Glycyrrhizae Preparata

Preparation method is with the preparation method in embodiment 1.

The preparation of No. 3.3 goods of embodiment

Raw material of Chinese medicine and weight portion thereof: 150 parts of Gekko Swinhoniss, 120 parts of Radix Asparagi, 120 parts of Bulbus Fritillariae Thunbergiis, 120 parts of Spica Prunellaes, 60 parts of Spina Gleditsiae, 80 parts of Sargassums, 80 parts of Fructus Liquidambaris, 60 parts of Semen Vaccariae, 80 parts of Pseudobulbus Cremastrae Seu Pleioness, 80 parts of Bombyx Batryticatus, 80 parts of Herba Erodiis, 70 parts of Scorpios, 70 parts of Fructus Hordei Germinatus, 70 parts of Radix Glycyrrhizae Preparata

Preparation method is with the preparation method in embodiment 1.

Take mode: each serving the water pill with being equivalent to 6g crude drug, every day 3 times, warm water delivery service.It within one month, is a course for the treatment of.

Clinical verification statistics

Within clinical 10 years, accept more than 3000 routine patients for medical treatment, 1-5 course cure rate 95%, effective percentage 98%.No. 1, No. 2, No. 3 goods do not have significant difference on clinical effectiveness.Therapeutic equivalence.

Criterion of therapeutical effect:

Cure: lump disappears, mastalgia disappears

Effective: mastalgia obviously alleviates or disappears, lump major diameter reduces more than 1/2nd.

Invalid: symptom is without change, and lump has no obviously and dwindles.

Model case 4 examples:

Wang, female, 35 years old, bilateral mastalgia, had lump 5 years, and mammography shows: severe is more chronic, massive, cyst type cyclomastopathy.Once took multi-medicament treatment, effect is undesirable.Take 10 days pain of No. 1 goods and disappear, continue to take 3 courses for the treatment of, lump disappears, and follows up a case by regular visits to not recurrence in 5 years.

Cao, female, 26 years old, often, in the moon premenstrual bimastism distending pain 5 years, mammography showed the tuberosity being dispersed in, average particulate diameter 3-6mm, a little higher than body of gland of density, is diagnosed as cyclomastopathy, once takes multi-medicament and alleviates, and after drug withdrawal, recurs.Take No. 2 goods and within 3 days, swell and ache and alleviate, serve on 2 months after distending pain tuberosity eliminate, follow up a case by regular visits to and within 2 years, have no recurrence.

Revive certain, female, 43 years old, when bilateral breast has lump 8 years angry, lump was bigger, the slight pain of companion, ultrasonic findings: in lobule and the large conduit of extralobular part and ductule epithelial proliferation, it is thick that the low echo of lactiferous ducts is irregular increasing, and maximum can reach 3-10mm.Diagnosis: bilateral breast ductal hyperplasia.Once taking multi-medicament fails to respond to any medical treatment.Take No. 1 goods 10 days, lump deliquescing, takes 1 course for the treatment of, and body of gland is homogeneous, rear consolidation 2 courses for the treatment of, and ultrasonic examination is normal, follows up a case by regular visits to not recurrence in 5 years.

Zhang, female, 34 years old, bilateral lump in breast 6 years, ultrasonic findings: irregular masses, in lump, be low echo, inhomogeneous.Diagnosis: bilateral breast adenoma hypertrophy, the heterodyne of taking medicine, the Duo Jia hospital of once going to a doctor, doctor advocates excision, and patient Zhang, for saving breast from damage, excises, take No. 3 goods 20 days, lump slightly disappears, and takes 3 courses for the treatment of, the attenuation of body of gland thickness, smooth, homogeneous, after continue again to take 2 courses for the treatment of, to consolidate curative effect, follow up a case by regular visits to not recurrence in 3 years.

Claims (7)

1. for cyclomastopathy patient's goods, described goods are made by the crude drug of following weight portion: Gekko Swinhonis 80-150 part, Radix Asparagi 60-120 part, Bulbus Fritillariae Thunbergii 60-120 part, Spica Prunellae 60-120 part, Spina Gleditsiae 20-60 part, Sargassum 40-80 part, Fructus Liquidambaris 40-80 part, Semen Vaccariae 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 30-80 part, Bombyx Batryticatus 20-80 part, Herba Erodii 20-80 part, Scorpio 20-70 part, Fructus Hordei Germinatus 20-70 part, Radix Glycyrrhizae Preparata 2-70 part.

2. goods according to claim 1, the crude drug of described weight portion is: Gekko Swinhonis 80-130 part, Radix Asparagi 60-100 part, Bulbus Fritillariae Thunbergii 60-100 part, Spica Prunellae 60-100 part, Spina Gleditsiae 20-40 part, Sargassum 40-70 part, Fructus Liquidambaris 40-60 part, Semen Vaccariae 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 40-70 part, Bombyx Batryticatus 30-70 part, Herba Erodii 30-80 part, Scorpio 40-70 part, Fructus Hordei Germinatus 20-60 part, Radix Glycyrrhizae Preparata 30-70 part.

3. goods according to claim 2, the crude drug of described weight portion is: 100 parts of Gekko Swinhoniss, 60 parts of Radix Asparagi, 80 parts of Bulbus Fritillariae Thunbergiis, 80 parts of Spica Prunellaes, 40 parts of Spina Gleditsiae, 40 parts of Sargassums, 40 parts of Fructus Liquidambaris, 40 parts of Semen Vaccariae, 60 parts of Pseudobulbus Cremastrae Seu Pleioness, 50 parts of Bombyx Batryticatus, 60 parts of Herba Erodiis, 50 parts of Scorpios, 40 parts of Fructus Hordei Germinatus, 5 parts of Radix Glycyrrhizae Preparata.

4. the purposes of the goods described in claim 1-3 any one in the medicine of preparation treatment cyclomastopathy.

5. treat a medicine for cyclomastopathy, its effective ingredient is the arbitrary described goods of claim 1～3.

6. medicine claimed in claim 5, its dosage form is pill.

7. medicine claimed in claim 6, described pill is water pill.