CN103750302A - Lycium chinense alcohol extract as well as preparation method and application thereof - Google Patents
Lycium chinense alcohol extract as well as preparation method and application thereof Download PDFInfo
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- 239000000284 extract Substances 0.000 title claims abstract description 61
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title claims abstract description 28
- 235000015468 Lycium chinense Nutrition 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 244000241872 Lycium chinense Species 0.000 title abstract description 5
- 238000000605 extraction Methods 0.000 title description 10
- 239000007788 liquid Substances 0.000 claims abstract description 26
- 238000004821 distillation Methods 0.000 claims abstract description 15
- 239000007787 solid Substances 0.000 claims abstract description 8
- 239000002775 capsule Substances 0.000 claims abstract description 5
- 239000000084 colloidal system Substances 0.000 claims abstract description 5
- 244000241838 Lycium barbarum Species 0.000 claims description 64
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 64
- 235000013399 edible fruits Nutrition 0.000 claims description 15
- 238000000926 separation method Methods 0.000 claims description 8
- 239000006228 supernatant Substances 0.000 claims description 7
- 239000002002 slurry Substances 0.000 claims description 6
- 235000011869 dried fruits Nutrition 0.000 claims description 3
- 230000035800 maturation Effects 0.000 claims description 2
- 235000020357 syrup Nutrition 0.000 claims description 2
- 239000006188 syrup Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 17
- 238000001035 drying Methods 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000000227 grinding Methods 0.000 abstract description 2
- 238000009776 industrial production Methods 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 239000000047 product Substances 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 11
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 239000002994 raw material Substances 0.000 description 8
- 239000008187 granular material Substances 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000011347 resin Substances 0.000 description 4
- 229920005989 resin Polymers 0.000 description 4
- 229920001353 Dextrin Polymers 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 235000008504 concentrate Nutrition 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 235000019425 dextrin Nutrition 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 238000003809 water extraction Methods 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 235000017784 Mespilus germanica Nutrition 0.000 description 2
- 244000182216 Mimusops elengi Species 0.000 description 2
- 235000000560 Mimusops elengi Nutrition 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 235000007837 Vangueria infausta Nutrition 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
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- 235000013376 functional food Nutrition 0.000 description 2
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- 238000001556 precipitation Methods 0.000 description 2
- 238000001223 reverse osmosis Methods 0.000 description 2
- 239000007901 soft capsule Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 229960004793 sucrose Drugs 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241001106041 Lycium Species 0.000 description 1
- 241000169546 Lycium ruthenicum Species 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 244000126002 Ziziphus vulgaris Species 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 235000020374 simple syrup Nutrition 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a lycium chinense alcohol extract as well as a preparation method and an application of the extract. According to the scheme, the extract is prepared by washing lycium chinense, drying naturally, grinding into pulp by using a colloid mill, and uniformly mixing with 40-100% ethanol, wherein the mixing weight ratio is 1:(10-20); extracting for 6-360 hours at 18-80 DEG C, separating solid from liquid, collecting the clear liquid, distilling for 1 hour at 55 DEG C under normal pressure, and further distilling and concentrating for 1.5-4 hours under the vacuum degree of 0.01-0.1Mpa and the distillation temperature of 20-70 DEG C. To conveniently have the extract, the extract can be further machined into grains, tablets, capsules and oral liquids. The method is simple and convenient to operate, low in cost, free of pollution and beneficial for industrial production.
Description
Technical field
The invention belongs to Chinese wolfberry fruit and extract manufacture field, be specifically related to a kind of matrimony vine alcohol-extracted extract and preparation method thereof and application.
Background technology
Matrimony vine taste is sweet and refreshing, nutritious, China is medicinal and edible with a long history to matrimony vine, as edible dry fruit, herbal cuisine and the dish of mainly containing of nutritious tonifying, be developed in recent years the product supply markets such as beverage, drinks, drying dried nuts, wolfberry fruit powder, medlar preserved fruit, met to some extent the part demand in market, but, as a kind of have in the life that the matrimony vine of high nutritive value and health-care efficacy is also far from being dissolved into ordinary citizen very much go, matrimony vine can't be widely used and more people is benefited.Along with the raising of people's living standard, pursue health, the hope of improving the quality of living is constantly brought forth new ideas health products trade, manufactures the more useful product with nutritve function to meet people's demand.Matrimony vine, as a kind of tonic Chinese herbal medicine that has long history in China, is constantly developed to different useful formulation products in recent years, and the mode of nourishing with different, has met the part market demand.Along with scientific and technological progress, the beneficiating ingredient of scientific research personnel from matrimony vine started with, and extracts respectively, and making matrimony vine is not only a kind of organic mixture, but from some distinctive composition Zhongmou County, ask its special efficacy, as LBP-X is extensively applied.
Due to diversity and the complexity that matrimony vine contains composition, a lot of single components are also difficult to effectively extracted or utilize.In prior art, take wolfberry fruit extract as the effective raw material application of some goods still for generally, for the active ingredient of matrimony vine is fully used, it is that a kind of technique is simple, production cost is low that its extract does not still lose, the reliable effective ways of effect.
In existing disclosed technology, as Chinese patent CN102924617A discloses " wolfberry fruit extract and preparation method thereof ", the method for this invention is to take Chinese wolfberry fruit as raw material, add water, then matrimony vine and aqueous mixtures are pulverized, obtain solid mixture slurries, slurries are concentrated with ultrafilter, obtain concentrate, in concentrate, add the ethanol of volumetric concentration 40-60%, standing, filter, in filtrate, add the ethanol of volumetric concentration 70-80%, staticly settle thing, dry, obtain dry thing.To be dried thing, then water dissolving, the solution that is greater than 10000 by ultrafiltration molecular cut off, concentrated, concentrate is adsorbed in non-polar macroporous resin, and the toluene wash-out that is 60-70% by concentration reclaims toluene, after being dried, concentrating, obtains wolfberry fruit extract.Therefrom can find out that this invention is through non-polar macroporous resin, to adsorb with water extract-alcohol precipitation again, then obtains product with toluene wash-out.Chinese patent CN102988605A is adopt " method of SCF-CO 2 wolfberry fruit extract ", in the lycium plant extract of the method extraction of this technology, is mainly LBP-X, and the content of its LBP-X reaches 17%.Chinese patent CN103044569A discloses " wolfberry fruit extract that contains matrimony vine acid and preparation method thereof ", matrimony vine acid and 2%-20% LBP-X that this technical scheme shows to contain 1%-10% in described wolfberry fruit extract, its preparation method comprise by matrimony vine raw material with reverse osmosis water wash away floating dust, reverse osmosis water lixiviate or heating extraction, filtration, the absorption of ion-exchange fibre post, wash-out, ultrafiltration, concentrated, sterilizing, spraying is dried and obtains product.It is jujube medlar medicinal extract that Chinese patent CN1101240A discloses what in " bean instant drink and production method thereof ", select, the preparation of this medicinal extract is date 4kg, the matrimony vine 1kg that takes free from insect pests, add approximately 3 times of amounts of water and be heated to 90 ℃-100 ℃, extract 2 hours, filter, filter filter residue, then extracting in water 1 hour, and three filtrates.Be condensed into the mixing medicinal extract (the 5th page of the 3rd section of 1-5 is capable for description) of same inventory weight ratio 1:1.Chinese patent CN102240035A discloses " a kind of preparation method of wolfberry extract health-care granules ", its technical scheme is after matrimony vine ultramicro grinding, to carry out supercritical carbon dioxide extracting, obtain liquid extract and solid-state extract remainder, then the water-soluble extraction of solid-state extract remainder is obtained to water-soluble extract, water-soluble extract by above-mentioned gained liquid extract and after concentrating mixes, add sucrose, dextrin, drying and crushing, is wolfberry extract health-care granules after adopting dry method granulation processes to granulate after sieving.Chinese patent CN101991709A discloses " method for preparing antioxidant lycium ruthenicum extract ", this invention lixiviate, high-pressure homogeneous, film is separated and macroreticular resin is separated, dry, obtain anti-oxidant black fruit lyceum extract.
From above-mentioned existing published technical scheme, can find out that prepared wolfberry fruit extract adopts water extraction, concentrated mostly; Water extraction, separation, resin adsorption, concentrated; Water extraction, alcohol precipitation, the technique such as concentrated, its complex process, time-consuming, production cost is high, is difficult to obtain cheap product to satisfy the demands of consumers.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of matrimony vine alcohol-extracted extract is provided, use it for food and functional food, the active ingredient of matrimony vine is fully extracted, and use is applied even more extensively in food and functional food, make this product with nourishing effect of matrimony vine obtain more multiextent application, meet the demand of people's cuisines health.
Another object of the present invention is to provide a kind of method of preparing described matrimony vine alcohol-extracted extract.
The present invention also aims to provide a kind of described matrimony vine alcohol-extracted extract as the application in food and nutriment.
Except as otherwise noted, percentage of the present invention is percetage by weight.
Object of the present invention is achieved by the following technical programs:
A matrimony vine alcohol-extracted extract, is made by following method: matrimony vine is cleaned, drained, adopt colloid mill to wear into slurry and mix with the ethanol of concentration 40-100%, mixed weight is than being 1:10-20; Under 18-80 ℃ of condition, extract 6-360h; Separation of Solid and Liquid, collects supernatant liquid; First air-distillation 1h under 55 ℃ of conditions, is then that 0.01-0.1Mpa, vapo(u)rizing temperature are distillation and concentration 1.5-4h under 20-70 ℃ of condition in vacuum, obtains required medicinal extract.
The invention provides a kind of method of preparing matrimony vine alcohol-extracted extract, the method comprises following sequential steps:
(1) matrimony vine is cleaned, drained, with colloid mill, wear into slurry;
(2) ethanol that is 40-100% by wolfberry fruit syrup with concentration mixes, and mixed weight is than being 1:10-20;
(3) under 18-80 ℃ of condition, extract 6-360h;
(4) Separation of Solid and Liquid, collects supernatant liquid;
(5) the air-distillation 1h at 55 ℃ of elder generation, is then that 0.01-0.1Mpa, vapo(u)rizing temperature are distillation and concentration 1.5-4h under 20-70 ℃ of condition in vacuum, obtains required medicinal extract.
Wherein said matrimony vine is fresh fructus lycii or the market dried fruit of lycium barbarum on sale after maturation.
Matrimony vine alcohol-extracted extract of the present invention, for edible convenience and needs, can also add pharmacy and/or food processing acceptable auxiliary agent to be further processed into the formulations for oral administration such as granule, tablet, capsule and oral liquid.
Beneficial effect of the present invention
1, alcohol extracting can fully be extracted the organic principle in matrimony vine, larger fragrance matter, the volatile oil component of matrimony vine Semi-polarity fully extracted simultaneously, beneficiating ingredient in matrimony vine is extracted to greatest extent, can make product obtain useful result of use, and improve products taste.
2, the composition in alcohol extracting process, matrimony vine being contained has reduced coarse hard material in matrimony vine after extracting, and its product is fine and smooth, granularity is little, is more conducive to absorption and the application of human body.
3, due to alcohol extracting matrimony vine medicinal extract, active ingredient is concentrated, use amount reduces, and gives off a strong fragrance.
4, ethanol can fully extract organic principle in matrimony vine, and particularly liposoluble constituent and fragrance matter are fully extracted, and makes the health-care efficacy of its medicinal extract be guaranteed and promote, and solvent can recycle and reuse, and process of producing product does not exist solvent contamination.
5, the present invention be advantageous in that, prepare yield of extract high, for expanding the exploitation of matrimony vine, provide new method and approach.
6, production technology of the present invention is simple, easy and simple to handle, production cost is low, and suitability for industrialized is produced.
The specific embodiment
Below in conjunction with embodiment and Application Example, the present invention is described in further detail, but they are not limitation of the invention.
Embodiment 1
Take 10 kilograms of well-done new fresh fructus lyciis, with pure water, clean and drain away the water, put into beater and break into homogenate, pack extractor into, adding 100L concentration is 95% ethanol, under 50 ℃ of conditions, uniform stirring adds heat soaking extraction 120h, with 300 order industrial filter cloths, carry out Separation of Solid and Liquid, collect supernatant liquid, the liquid obtaining is first at 55 ℃ of air-distillation 1h, then in vacuum, be that 0.05Mpa, vapo(u)rizing temperature are distillation and concentration 3h under 35 ℃ of conditions, obtain 5200 grams of medicinal extract.
Embodiment 2
Take 10 kilograms of well-done new fresh fructus lyciis, with pure water, clean and drain away the water, put into beater and break into homogenate, pack extractor into, adding 150L concentration is 55% ethanol, under 70 ℃ of conditions, uniform stirring adds heat soaking extraction 6h, with 300 order industrial filter cloths, carry out Separation of Solid and Liquid, collect supernatant liquid, the liquid obtaining is first at 55 ℃ of air-distillation 1h, then in vacuum, be that 0.1Mpa, vapo(u)rizing temperature are distillation and concentration 1.5h under 70 ℃ of conditions, obtain 5050 grams of medicinal extract.
Embodiment 3
Take 10 kilograms of dried fruit of lycium barbarum, with pure water, clean and drain away the water, put into beater and break into homogenate, pack extractor into, adding 200L concentration is 40% ethanol, under 18 ℃ of conditions, uniform stirring adds heat soaking extraction 360h, with 300 order industrial filter cloths, carry out Separation of Solid and Liquid, collect supernatant liquid, the liquid obtaining is first at 55 ℃ of air-distillation 1h, then in vacuum, be that 0.01Mpa, vapo(u)rizing temperature are distillation and concentration 4h under 20 ℃ of conditions, obtain 6850 grams of medicinal extract.
Embodiment 4: the preparation of tablet
With following raw materials according, by the production method of general tablet, produce every consumption:
Matrimony vine alcohol-extracted extract 200mg, sweet mellow wine 705.8mg, sugar 260mg, methylcellulose 18mg, saccharin sodium 0.6mg, matrimony vine essence 3.6mg, dolomol 12mg.
Embodiment 5: the preparation of soft capsule
With following raw materials according, by the production method of general soft capsule, produce every consumption:
Matrimony vine alcohol-extracted extract 100mg, vitamin E 25mg, Tea Polyphenols 25mg, Oleum Citri Reticulatae 30mg, corn oil 170mg.
Embodiment 6: the preparation of capsule
With following raw materials according, by the production method of general capsule, produce every consumption:
Matrimony vine alcohol-extracted extract 150mg, microcrystalline cellulose 50mg, dextrin 50mg, sodium carboxymethylcellulose 6mg, starch 244mg.
Embodiment 7: the preparation of granule
With following raw materials according, by the production method of general granule, produce every gram of consumption:
Matrimony vine alcohol-extracted extract 20mg, dextrin 300mg, cane sugar powder 680mg.
The preparation of embodiment 8 oral liquids
With following raw materials according, by the production method of general oral liquid, produce every 100 grams of consumptions: matrimony vine alcohol-extracted extract 0.5g, simple syrup 20g, Sodium Benzoate 0.1g, propane diols 3g, matrimony vine essence 0.3g, distilled water 76.1g.
Claims (4)
1. a matrimony vine alcohol-extracted extract, is characterized in that matrimony vine to clean, drain, and adopts colloid mill to wear into slurry and mixes with the ethanol of concentration 40-100%, and mixed weight is than being 1:10-20; Under 18-80 ℃ of condition, extract 6-360h; Separation of Solid and Liquid, collects supernatant liquid; First air-distillation 1h under 55 ℃ of conditions, is then that 0.01-0.1Mpa, vapo(u)rizing temperature are distillation and concentration 1.5-4h under 20-70 ℃ of condition in vacuum, obtains required medicinal extract.
2. a matrimony vine alcohol-extracted extract as claimed in claim 1, is characterized in that described matrimony vine is fresh fructus lycii after maturation or commercially available dried fruit of lycium barbarum.
3. a preparation method for matrimony vine alcohol-extracted extract as claimed in claim 1, is characterized in that comprising following sequential steps:
(1) matrimony vine is cleaned, drained, with colloid mill, wear into slurry;
(2) ethanol that is 40-100% by wolfberry fruit syrup with concentration mixes, and mixed weight is than being 1:10-20;
(3) under 18-80 ℃ of condition, extract 6-360h;
(4) Separation of Solid and Liquid, collects supernatant liquid;
(5) the air-distillation 1h at 55 ℃ of elder generation, is then that 0.01-0.1Mpa, vapo(u)rizing temperature are distillation and concentration 1.5-4h under 20-70 ℃ of condition in vacuum, obtains required medicinal extract.
4. preparation method according to claim 2, is characterized in that: can also further be processed into particle, tablet, capsule and oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310742533.2A CN103750302A (en) | 2013-12-30 | 2013-12-30 | Lycium chinense alcohol extract as well as preparation method and application thereof |
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| CN201310742533.2A CN103750302A (en) | 2013-12-30 | 2013-12-30 | Lycium chinense alcohol extract as well as preparation method and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106281905A (en) * | 2016-11-10 | 2017-01-04 | 湄潭县京贵茶树花产业发展有限公司 | Flos Camelliae sinensis health promoting wine preparation method |
| CN106387564A (en) * | 2016-08-30 | 2017-02-15 | 宁夏沃福百瑞枸杞产业股份有限公司 | Preparation method of dried Chinese wolfberry fruit concentration pulp |
| CN108813022A (en) * | 2018-08-01 | 2018-11-16 | 上海应用技术大学 | A kind of rose tea and preparation method thereof with reduction postprandial blood sugar function |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1620915A (en) * | 2005-01-04 | 2005-06-01 | 白栓锁 | Wolfberry fruit extraction method and food produced by same |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1620915A (en) * | 2005-01-04 | 2005-06-01 | 白栓锁 | Wolfberry fruit extraction method and food produced by same |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106387564A (en) * | 2016-08-30 | 2017-02-15 | 宁夏沃福百瑞枸杞产业股份有限公司 | Preparation method of dried Chinese wolfberry fruit concentration pulp |
| CN106281905A (en) * | 2016-11-10 | 2017-01-04 | 湄潭县京贵茶树花产业发展有限公司 | Flos Camelliae sinensis health promoting wine preparation method |
| CN108813022A (en) * | 2018-08-01 | 2018-11-16 | 上海应用技术大学 | A kind of rose tea and preparation method thereof with reduction postprandial blood sugar function |
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Application publication date: 20140430 |