CN103735839A - Traditional Chinese medicine external application agent for treating diabetic foot - Google Patents
Traditional Chinese medicine external application agent for treating diabetic foot Download PDFInfo
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- CN103735839A CN103735839A CN201410020375.4A CN201410020375A CN103735839A CN 103735839 A CN103735839 A CN 103735839A CN 201410020375 A CN201410020375 A CN 201410020375A CN 103735839 A CN103735839 A CN 103735839A
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Abstract
The invention discloses a traditional Chinese medicine external application agent for treating diabetic foot. The diabetic foot belongs to the scope of gangrene of finger or toe of the traditional Chinese medicine. The basic pathogenesis of the diabetic foot includes vital energy deficiency, collaterals obstructed with extravasated blood in local tissue, accumulated water-dampness, and easy invasion of exogenous evil. The traditional Chinese medicine external application agent is prepared from Chinese herbs Japanese angelica tree root bark, polygonatum kingianum, smilax riparia, pottsia root, elecampane, salix hypoleuca, vetch and wahlenbergia marginata through the steps of grinding the raw materials into powder and blending the powder with normal saline into a paste; the traditional Chinese medicine external application agent is applied to the wounds. Clinical observation indicates that the total effective rate of the traditional Chinese medicine external application agent reaches 93.3%, and is obviously superior to 74.7% of the control group, therefore, the traditional Chinese medicine external application agent is obvious in curative effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of external application of Chinese medicine agent for the treatment of diabetic foot.
Diabetic foot (DiabeticFoot, DF) is infection, ulcer, the gangrene at the following position of diabetes (DiabeticM eHitus, DM) patient's ankle joint, is one of diabetes important complication.Unanimously think at present, neural and vascular lesion is the pathogenesis basis of glycosuria foot.Because long-term lower limb vascular and microcirculatory pathological changes, make sclerosis of blood vessels, narrow, affect blood supply, and neuropathy can make the pedal skin threshold of feelings rise, plantar pressure bearing position change etc.Diabetes merge acromelic gangrene and are difficult to cure.For many years, the acromelic gangrene limbs to serious, often adopt surgery amputation, make patient cause permanent disbility.Family and society are brought to very big burden.Inventor utilizes Diabetes Mellitus Treated With Traditional Chinese Medicine foot in clinical practice for many years, has obtained good curative effect.
Summary of the invention
The object of this invention is to provide a kind of external application of Chinese medicine agent for the treatment of diabetic foot.It is abnormal that primary disease belongs to motherland's medical science " necrosis " model.Its basic pathogenesis is that healthy energy is deficient, local organization congestion resistance network, and water is wet to be gathered, and is subject to outer Guo and takes advantage of.
The object of the invention is to be achieved through the following technical solutions.The external application of Chinese medicine agent of this treatment diabetic foot is comprised of the Chinese medicine of following weight portion: Cortex Araliae Elatae Radicis 15-30 part, Rhizoma Polygonati 9-15 part, Radix et Rhizoma Smilacis Ripariae 9-18 part, Radix Pottsiae Laxiflorae 7-15 part, Radix cocculi trilobi 9-21 part, Radix Salicis Hypoleucae 15-25 part, Radix seu Folium Viciae Unijugae 5-12 part, Herba Wahlenbergiae 6-15 part.
Preferably, the external application of Chinese medicine agent of this treatment diabetic foot is comprised of the Chinese medicine of following weight portion: 22 parts of Cortex Araliae Elatae Radiciss, 12 parts of Rhizoma Polygonatis, 15 parts of Radix et Rhizoma Smilacis Ripariae, 11 parts of Radix Pottsiae Laxifloraes, 15 parts of Radix cocculi trilobis, 20 parts of Radix Salicis Hypoleucae, 8 parts of Radix seu Folium Viciae Unijugaes, 10 parts of Herba Wahlenbergiaes.
Preparation method: above Chinese medicine is ground to form to powdery, then reconcile into pasty state with normal saline.
In side: Rhizoma Polygonati invigorating the spleen and replenishing QI, profit cardiopulmonary, bone and muscle strengthening; Cortex Araliae Elatae Radicis invigorating QI and tranquilization, essence strengthening and the kidney invigorating, dispelling, collateral-activating; Radix et Rhizoma Smilacis Ripariae QI invigorating, relaxing muscles and tendons and activating QI and blood in the collateral, invigorate blood circulation; Radix Pottsiae Laxiflorae blood circulation, expelling wind and removing dampness; Radix cocculi trilobi wind-damp dispelling, removing toxic substances, detumescencing diuresis, pain relieving; Radix Salicis Hypoleucae expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling; Radix seu Folium Viciae Unijugae tonify deficiency; Herba Wahlenbergiae tonify deficiency, induce sweat.
Clinical data
1, the routine patient of physical data 300 all carrys out in February, 2000 to 2007 year outpatient service in the November inpatient of self-institute.Be divided at random each 150 examples for the treatment of group and matched group.Treatment group man 100 examples, female's 50 examples; 32～79 years old age, average 63.1 years old; The course of disease 6 days to 20 months, average 5 months.Matched group man 80 examples, female's 70 examples; 29～80 years old age, average 68.8 years old; The course of disease 9 days to 18 months, average 8 months.Induced factor: scald 50 examples, wound, extruding 30 examples; Paronychia 25 examples, electricity wound 18 examples, tinea pedis 30 examples, without obvious inducement 147 examples; Ulcer spot: toes 190 examples, vola 50 examples, heel 60 examples.Be the ulcer at the following position of ankle joint, ulcer area is (1.5～11) cmX (1.5～11) cn
2too little not etc., the degree of depth by deep fascia to sclerotin.Get rid of the foot symptom that Other diseases causes; 1～12 month treatment time, average 7 months.
2, Therapeutic Method treatment group takes Cortex Araliae Elatae Radicis 22g, Rhizoma Polygonati 12g, Radix et Rhizoma Smilacis Ripariae 15g, Radix Pottsiae Laxiflorae 11g, Radix cocculi trilobi 15g, Radix Salicis Hypoleucae 20g, Radix seu Folium Viciae Unijugae 8g, Herba Wahlenbergiae 10g.By above Chinese medicine mixed grinding powdering, and reconcile into pasty state with normal saline, spread on wound surface.With sterile gauze, wrap up.Matched group soaks sliver with 1 ‰ ethacridines and spreads on wound surface.Change dressings 1 two groups of equal every days, and 30d is a course for the treatment of, statistical result after two courses for the treatment of.
3, criterion of therapeutical effect recovery from illness: wound surface is entirely new skin and covers, heals; Effective: the above area of wound healing 1/2; Effective: wound surface area healing 1/4～1/2; Invalid: wound surface area healing less than 1/4 or expansion.
4, therapeutic outcome treatment group and treatment of control group after two courses for the treatment of Comparison of therapeutic in Table 1.
Table 1 treatment group and matched group Comparison of therapeutic
Note: compare P<0.01 with matched group.
Two groups of relatively healing rate, total effective rates for the treatment of groups, be obviously better than healing rate, the total effective rate of matched group, has comparability.(P<0.05)。
The specific embodiment
Embodiment mono-: take Cortex Araliae Elatae Radicis 22g, Rhizoma Polygonati 12g, Radix et Rhizoma Smilacis Ripariae 15g, Radix Pottsiae Laxiflorae 11g, Radix cocculi trilobi 15g, Radix Salicis Hypoleucae 20g, Radix seu Folium Viciae Unijugae 8g, Herba Wahlenbergiae 10g, above Chinese medicine is ground to form to powdery, with normal saline, reconcile into pasty state again, spread on wound surface, with sterile gauze, wrap up.
Embodiment bis-: take Cortex Araliae Elatae Radicis 30g, Rhizoma Polygonati 9g, Radix et Rhizoma Smilacis Ripariae 9g, Radix Pottsiae Laxiflorae 15g, Radix cocculi trilobi 9g, Radix Salicis Hypoleucae 15g, Radix seu Folium Viciae Unijugae 12g, Herba Wahlenbergiae 6g, above Chinese medicine is ground to form to powdery, with normal saline, reconcile into pasty state again, spread on wound surface, with sterile gauze, wrap up.
Embodiment tri-: take Cortex Araliae Elatae Radicis 15g, Rhizoma Polygonati 15g, Radix et Rhizoma Smilacis Ripariae 18g, Radix Pottsiae Laxiflorae 7g, Radix cocculi trilobi 21g, Radix Salicis Hypoleucae 25g, Radix seu Folium Viciae Unijugae 5g, Herba Wahlenbergiae 15g, above Chinese medicine is ground to form to powdery, with normal saline, reconcile into pasty state again, spread on wound surface, with sterile gauze, wrap up.
Claims (2)
1. treat an external application of Chinese medicine agent for diabetic foot, it is characterized in that this external application of Chinese medicine agent is comprised of the Chinese medicine of following weight portion: Cortex Araliae Elatae Radicis 15-30 part, Rhizoma Polygonati 9-15 part, Radix et Rhizoma Smilacis Ripariae 9-18 part, Radix Pottsiae Laxiflorae 7-15 part, Radix cocculi trilobi 9-21 part, Radix Salicis Hypoleucae 15-25 part, Radix seu Folium Viciae Unijugae 5-12 part, Herba Wahlenbergiae 6-15 part.
2. a kind of external application of Chinese medicine agent for the treatment of diabetic foot according to claim 1, is characterized in that this external application of Chinese medicine agent is comprised of the Chinese medicine of following weight portion: 22 parts of Cortex Araliae Elatae Radiciss, 12 parts of Rhizoma Polygonatis, 15 parts of Radix et Rhizoma Smilacis Ripariae, 11 parts of Radix Pottsiae Laxifloraes, 15 parts of Radix cocculi trilobis, 20 parts of Radix Salicis Hypoleucae, 8 parts of Radix seu Folium Viciae Unijugaes, 10 parts of Herba Wahlenbergiaes.
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| CN201410020375.4A CN103735839B (en) | 2014-01-09 | 2014-01-09 | A kind of external traditional Chinese medicinal application for the treatment of diabetic foot |
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| CN201410020375.4A CN103735839B (en) | 2014-01-09 | 2014-01-09 | A kind of external traditional Chinese medicinal application for the treatment of diabetic foot |
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| CN103735839A true CN103735839A (en) | 2014-04-23 |
| CN103735839B CN103735839B (en) | 2016-04-06 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977216A (en) * | 2014-05-17 | 2014-08-13 | 魏本正 | Traditional Chinese medicinal preparation for treating irradiated brain stem type myeloen cephalospinal disease |
| CN105920281A (en) * | 2016-06-20 | 2016-09-07 | 宋梅 | Traditional Chinese medicine for treating blood stasis vessel obstruction syndrome diabetic foot and preparation method thereof |
| CN107469001A (en) * | 2017-08-29 | 2017-12-15 | 肖棚元 | A kind of Chinese medicine for treating the gangrene of finger or toe |
Citations (5)
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| CN1343502A (en) * | 2000-09-18 | 2002-04-10 | 武邵 | Ulcer medicine for treating subcutaneous ulcer |
| CN1463709A (en) * | 2002-06-05 | 2003-12-31 | 刘侠 | Yuzu capsule |
| CN101850049A (en) * | 2009-10-16 | 2010-10-06 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic foot |
| CN101954024A (en) * | 2010-09-29 | 2011-01-26 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicament for treating diabetic foot |
| CN102274447A (en) * | 2011-08-27 | 2011-12-14 | 赵国辉 | Medicinal composition for treating diabetes |
-
2014
- 2014-01-09 CN CN201410020375.4A patent/CN103735839B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343502A (en) * | 2000-09-18 | 2002-04-10 | 武邵 | Ulcer medicine for treating subcutaneous ulcer |
| CN1463709A (en) * | 2002-06-05 | 2003-12-31 | 刘侠 | Yuzu capsule |
| CN101850049A (en) * | 2009-10-16 | 2010-10-06 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic foot |
| CN101954024A (en) * | 2010-09-29 | 2011-01-26 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicament for treating diabetic foot |
| CN102274447A (en) * | 2011-08-27 | 2011-12-14 | 赵国辉 | Medicinal composition for treating diabetes |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977216A (en) * | 2014-05-17 | 2014-08-13 | 魏本正 | Traditional Chinese medicinal preparation for treating irradiated brain stem type myeloen cephalospinal disease |
| CN105920281A (en) * | 2016-06-20 | 2016-09-07 | 宋梅 | Traditional Chinese medicine for treating blood stasis vessel obstruction syndrome diabetic foot and preparation method thereof |
| CN107469001A (en) * | 2017-08-29 | 2017-12-15 | 肖棚元 | A kind of Chinese medicine for treating the gangrene of finger or toe |
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| CN103735839B (en) | 2016-04-06 |
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Effective date of registration: 20161115 Address after: 271016 the Great Wall Road, Shandong, Tai'an, No. 619 Patentee after: Taishan Hospital Address before: 271016 middle of the Great Wall Road, Shandong, Tai'an Province, Taishan Medical University Patentee before: Xiao Yuliang |
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